OOIR: Observatory of International Research

Papers

(The H4-Index of International Journal of Biological Sciences is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Crosstalk between PML and p53 in response to TGF-β1: A new mechanism of cardiac fibroblast activation	163
IFNAR(-/-) Mice Constitute a Suitable Animal Model for Epizootic Hemorrhagic Disease Virus Study and Vaccine Evaluation	146
PAK1 overexpression promotes myxofibrosarcoma angiogenesis through STAT5B-mediated CSF2 transactivation: clinical and therapeutic relevance of amplification and nuclear entry	145
Targeting Type I Interferon Induction and Signaling: How Zika Virus Escapes from Host Innate Immunity	133
Digging out MDIG from the mess of H3K9me3, OTX2 and MYC signaling in human cancers	102
Broadening horizons: the multifaceted functions of ferroptosis in kidney diseases	90
Tsp2 Facilitates Tumor-associated Fibroblasts Formation and Promotes Tumor Progression in Retroperitoneal Liposarcoma	90
Role Of YAP Signaling in Regulation of Programmed Cell Death and Drug Resistance in Cancer	89
Engineering neoantigen vaccines to improve cancer personalized immunotherapy	88
LncRNA-COX2 inhibits Fibroblast Activation and Epidural Fibrosis by Targeting EGR1	86
As a Novel Tumor Suppressor, LHPP Promotes Apoptosis by Inhibiting the PI3K/AKT Signaling Pathway in Oral Squamous Cell Carcinoma	79
The Essential Role of Angiogenesis in Adenosine 2A Receptor Deficiency-mediated Impairment of Wound Healing Involving c-Ski via the ERK/CREB Pathways	79
Inhibition of α4β1 Integrin Activity by Small Tellurium Compounds Regulates PD-L1 Expression and Enhances Antitumor Effects	77
Neutrophil extracellular traps trigger alveolar epithelial cell necroptosis through the cGAS-STING pathway during acute lung injury in mice	76
Enhancing mitophagy by ligustilide through BNIP3-LC3 interaction attenuates oxidative stress-induced neuronal apoptosis in spinal cord injury	74
FIBP interacts with transcription factor STAT3 to induce EME1 expression and drive radioresistance in lung adenocarcinoma	73
Targeting METTL3 enhances the chemosensitivity of non-small cell lung cancer cells by decreasing ABCC2 expression in an m⁶A-YTHDF1-dependent manner	70
Erratum for Ferroptosis-related Genes for Overall Survival Prediction in Patients with Colorectal Cancer can be Inhibited by Gallic acid	69
Neuraminidase 1 deficiency attenuates cardiac dysfunction, oxidative stress, fibrosis, inflammatory via AMPK-SIRT3 pathway in diabetic cardiomyopathy mice	67
Uncovering a Novel Functional Interaction Between Adult Hepatic Progenitor Cells, Inflammation and EGFR Signaling During Bile Acids-Induced Injury	64
The dysadherin/FAK axis promotes individual cell migration in colon cancer	64
A putative role for lactate in the crosstalk between chemokines and glycolysis in solid cancer	62
SMURF2 facilitates ubiquitin-mediated degradation of ID2 to attenuate lung cancer cell proliferation	59
Molecular mechanisms of pyroptosis and its role in anti-tumor immunity	59
Loss of DDRGK1 impairs IRE1α UFMylation in spondyloepiphyseal dysplasia	57

Dendropanoxide Alleviates Thioacetamide-induced Hepatic Fibrosis via Inhibition of ROS Production and Inflammation in BALB/_C Mice	57
Metformin induces cell cycle arrest, apoptosis and autophagy through ROS/JNK signaling pathway in human osteosarcoma: Erratum	56
Nicotinamide adenine dinucleotide kinase promotes lymph node metastasis of NSCLC via activating ID1 expression through BMP pathway	56
FBXO22 Suppresses Metastasis in Human Renal Cell Carcinoma via Inhibiting MMP-9-Mediated Migration and Invasion and VEGF-Mediated Angiogenesis	55
Crosstalk of ubiquitin system and non-coding RNA in fibrosis	54
S100A4 Is a Key Facilitator of Thoracic Aortic Dissection	53
Humoral and Cellular Immune Responses of COVID-19 vaccines against SARS-Cov-2 Omicron variant: a systemic review	53
NOP2-mediated 5-methylcytosine modification of APOL1 messenger RNA activates PI3K-Akt and facilitates clear cell renal cell carcinoma progression	52
Transcription Factor E2F4 Promote Proliferation, Migration, and Invasion of Gastric Cancer Cells by transcriptionally activating DSCC1	49
Antioxidant genes in cancer and metabolic diseases: Focusing on Nrf2, Sestrin, and heme oxygenase 1	48
Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells	47
Single-cell transcriptomics reveals zinc and copper ions homeostasis in epicardial adipose tissue of heart failure	46
Integrated pathological analysis to develop a Gal-9 based immune survival stratification to predict the outcome of lung large cell neuroendocrine carcinoma and its usefulness in immunotherapy	45
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients	44
Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis: Erratum	43
MKL-1 suppresses ferroptosis by activating system Xc- and increasing glutathione synthesis	43
Myeloid cell-expressed MNDA enhances M2 polarization to facilitate the metastasis of hepatocellular carcinoma	41
Tectorigenin targets PKACα to promote GLUT4 expression in skeletal muscle and improve insulin resistance in vitro and in vivo	41
BRD4 Inhibitor AZD5153 Suppresses the Proliferation of Colorectal Cancer Cells and Sensitizes the Anticancer Effect of PARP Inhibitor: Erratum	41