OOIR: Observatory of International Research

Papers

(The H4-Index of International Journal of Biological Sciences is 57. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
A putative role for lactate in the crosstalk between chemokines and glycolysis in solid cancer	308
Stem cells enhance their chondrogenic differentiation in hydrogels by mechanical tumbling	224
The dysadherin/FAK axis promotes individual cell migration in colon cancer	213
MKL-1 suppresses ferroptosis by activating system Xc- and increasing glutathione synthesis	208
Alleviation of mutant TDP-43-mediated neuropathology by inducible stem cells in monkeys	204
Crosstalk between arachidonic acid metabolism and glycolysis drives integrated metabolic-inflammatory reprogramming in macrophages	162
Mechanistic role of metal-responsive transcription factor-1 (MTF-1) in cadmium-induced prostate carcinogenesis	159
Targeting the HSP60/p53 Axis with Extracellular Vesicle-Delivered siRNA Reprograms Glycolysis in Prostate Cancer	157
Exosomes in Genitourinary Cancers: Emerging Mediators of Drug Resistance and Promising Biomarkers	149
Nlp-dependent ER-to-Golgi transport	134
GIPC1 Restrains the Progression and Chemoresistance of Colorectal Cancer by Regulating TTC7B/mTOR/NF-κB Axis	133
Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells	133
p53 and MYC-regulated squalene epoxidase as Achilles heel in colorectal cancer	113
Reconstruction of the Hepatic Microenvironment and Pathological Changes Underlying Type II Diabetes through Single-Cell RNA Sequencing	112
Excessive Kynurenine Metabolism Impairs Lysosomal acidification and Triggers mtDNA Release via the AHR/CISH/ATP6V1A Axis in Decidual Macrophages Associated with Unexplained Recurrent Pregnancy Loss	108
Dysregulated Ribosome Biogenesis Is a Targetable Vulnerability in Triple-Negative Breast Cancer: MRPS27 as a Key Mediator of the Stemness-inhibitory Effect of Lovastatin	108
Cancer-associated fibroblasts promote migration and invasion of non-small cell lung cancer cells via METTL3-mediated RAC3 m⁶A modification	105
SESN2 inhibits tubular exosome secretion and diabetic kidney disease progression by restoring the autophagy‒lysosome pathway	98
Gut Microbiota-Driven Pathways Linking Chronic Stress to Tumor Progression	94
Loss of DDRGK1 impairs IRE1α UFMylation in spondyloepiphyseal dysplasia	94
Antioxidant genes in cancer and metabolic diseases: Focusing on Nrf2, Sestrin, and heme oxygenase 1	93
ETV4 interacts with LOXL2 to induce epigenetic activation of NID1 during colorectal cancer progression	93
Macrophages in Focus: Key Drivers and Therapeutic Opportunities in Diabetic Kidney Disease	91
Comprehensive Histopathology Imaging in Pancreatic Biopsies: High Definition Infrared Imaging with Machine Learning Approach	89
Digging out MDIG from the mess of H3K9me3, OTX2 and MYC signaling in human cancers	88

A crosstalk between tumor cells and adipocytes facilitates tumor cell migration and invasion	80
Extracellular vesicles, the emerging mirrors of brain physiopathology	78
Pathogenesis and treatment strategies of sepsis-induced myocardial injury: modern and traditional medical perspectives	76
TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease via nitric oxide production	75
Inhibition of the HMGB1/RAGE axis protects against cisplatin-induced ototoxicity via suppression of inflammation and oxidative stress	73
Targeting Lysosomes for Enhanced Anti-Cancer Therapeutics and Immune Response	72
SDPR Inhibits TGF-β Induced Cancer Metastasis Through Fatty Acid Oxidation Regulation in Gastric Cancer	72
Interferon Regulatory Factor 4 Recruits Immature B Cells to Signal Tertiary Lymphoid Structure Immaturity and Progression of Clear Cell Renal Cell Carcinoma	71
Therapeutic Activation of PPARα Inhibits Transformed Follicular Lymphoma Tumorigenesis via the FOXM1 Signaling Pathway	71
The Cyclin-Dependent Kinase 8 Inhibitor E966-0530-45418 Attenuates Pulmonary Fibrosis In Vitro and In Vivo	70
Outer Membrane Vesicles Derived from Oral Bacteria Act as a Dagger in Host Immunity: Insight Tips from Local Diseases to Systemic Effects	70
Exosomes: a promising microenvironment modulator for spinal cord injury treatment	68
Piezo1-driven mechanotransduction regulates mitochondrial biogenesis by AMPK/SIRT1-mediated PGC-1α deacetylation to ameliorate bone loss in disuse osteoporosis	67
Novel Role of the SIRT1 in Endocrine and Metabolic Diseases	67
CD151 promotes Colorectal Cancer progression by a crosstalk involving CEACAM6, LGR5 and Wnt signaling via TGFβ1: Erratum	67
Altered Heme and Redox Homeostasis Underpin Late-onset Alzheimer's Disease	65
IL-38 Aggravates Atopic Dermatitis via Facilitating Migration of Langerhans cells	63
TBX21 inhibits colorectal cancer metastasis through ARHGAP29/GSK3β inhibitory signaling- and MYCT1/ZO-1 signaling-dependent manner	63
Comprehensive Analyses Reveal Effects on Tumor Immune Infiltration and Immunotherapy Response of APOBEC Mutagenesis and Its Molecular Mechanisms in Esophageal Squamous Cell Carcinoma	62
Ugonin P mitigates osteolytic bone metastasis by suppressing MDK via upregulating miR-223-3p expression	62
Orphan Nuclear Receptor NR4A1 Promotes Proliferation and Osteogenic Differentiation of Valvular Interstitial Cells through Activation of CCND2	62
NUF2 Drives Cholangiocarcinoma Progression and Migration via Inhibiting Autophagic Degradation of TFR1	62
PROX1-mediated epigenetic silencing of SIRT3 contributes to proliferation and glucose metabolism in colorectal cancer	60
Dual-specificity tyrosine-regulated kinase 4 modulates the STAT3-FOS signaling axis to inhibit hepatitis B virus replication via autophagy	60
PSMC6 regulation of ovarian cancer cisplatin resistance unravels a new mode for proteasome targeting	60
Polysaccharide isolated from Grifola frondosa eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T cells responses	60
Immunosenescence, Physical Exercise, and their Implications in Tumor Immunity and Immunotherapy	59
NLRX1 Drives Prostate Cancer Progression Through Activation of AKT and ERK Signaling Pathways	59
Oxidative stress promotes liver fibrosis by modulating the microRNA-144 and SIN3A-p38 pathways in hepatic stellate cells	58
Paris saponin VII reverses resistance to PARP inhibitors by regulating ovarian cancer tumor angiogenesis and glycolysis through the RORα/ECM1/VEGFR2 signaling axis	58
N-Acetylcysteine Alleviates Depressive-Like Behaviors in Adolescent EAAC1^-/- Mice and Early Life Stress Model Rats	58
Novel glycoprotein SBSPON suppressed bladder cancer through the AKT signal pathway by inhibiting HSPA5 membrane translocation	58
The Crosstalk between Autophagy and Nrf2 Signaling in Cancer: from Biology to Clinical Applications	57
Extracellular Vesicles in Mental Disorders: A State-of-art Review	57