OOIR: Observatory of International Research

Papers

(The H4-Index of International Journal of Biological Sciences is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells	218
mRNA vaccines for COVID-19: what, why and how	213
Regulation of exosome production and cargo sorting	210
Interaction between Aβ and Tau in the Pathogenesis of Alzheimer's Disease	192
Immunotherapy in colorectal cancer: current achievements and future perspective	171
Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer	148
Underlying the Mechanisms of Doxorubicin-Induced Acute Cardiotoxicity: Oxidative Stress and Cell Death	140
Dihydroartemisinin: A Potential Natural Anticancer Drug	122
Long COVID and its Management	122
Forsythoside A Mitigates Alzheimer's-like Pathology by Inhibiting Ferroptosis-mediated Neuroinflammation via Nrf2/GPX4 Axis Activation	121
Neutrophil extracellular traps mediate m⁶A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells	119
Current advances in the development of SARS-CoV-2 vaccines	113
GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential	113
Ferroptosis-Related Long Non-Coding RNA signature predicts the prognosis of Head and neck squamous cell carcinoma	107
VEGF/VEGFR-Targeted Therapy and Immunotherapy in Non-small Cell Lung Cancer: Targeting the Tumor Microenvironment	90
Tumor heterogeneity reshapes the tumor microenvironment to influence drug resistance	86
Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway	83
Artificial intelligence in the diagnosis of COVID-19: challenges and perspectives	81
The Landscape Of Alpha Fetoprotein In Hepatocellular Carcinoma: Where Are We?	79
Construction and applications of SARS-CoV-2 pseudoviruses: a mini review	78
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression	78
The role of ubiquitination and deubiquitination in tumor invasion and metastasis	77
Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages	77
The role of RNA m⁵C modification in cancer metastasis	77
Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy	76

The Impact of TRPV1 on Cancer Pathogenesis and Therapy: A Systematic Review	76
CD47/SIRPα pathway mediates cancer immune escape and immunotherapy	73
LncRNA H19: A novel oncogene in multiple cancers	72
Smad3 Signatures in Renal Inflammation and Fibrosis	70
Integrated Machine Learning and Bioinformatic Analyses Constructed a Novel Stemness-Related Classifier to Predict Prognosis and Immunotherapy Responses for Hepatocellular Carcinoma Patients	69
USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway	69
A Positive Feedback Loop between Inactive VHL-Triggered Histone Lactylation and PDGFRβ Signaling Drives Clear Cell Renal Cell Carcinoma Progression	69
Attitudes toward COVID-19 vaccines in Chinese college students	68
A combination therapy of Phages and Antibiotics: Two is better than one	67
Ferroptosis in Cancer Progression: Role of Noncoding RNAs	67
Berberine ameliorates DSS-induced intestinal mucosal barrier dysfunction through microbiota-dependence and Wnt/β-catenin pathway	66
Functional and Structural Diversity of Insect Glutathione S-transferases in Xenobiotic Adaptation	64
An Overview: The Diversified Role of Mitochondria in Cancer Metabolism	63
Application of radiomics and machine learning in head and neck cancers	62
HPV E6/E7 promotes aerobic glycolysis in cervical cancer by regulating IGF2BP2 to stabilize m⁶A-MYC expression	61
Understanding the Effects of Gut Microbiota Dysbiosis on Nonalcoholic Fatty Liver Disease and the Possible Probiotics Role: Recent Updates	61
Mitophagy alleviates cisplatin-induced renal tubular epithelial cell ferroptosis through ROS/HO-1/GPX4 axis	59
miR-223: An Effective Regulator of Immune Cell Differentiation and Inflammation	59
CAR-T Cell Therapy for Breast Cancer: From Basic Research to Clinical Application	57
Progress of Breast Cancer basic research in China	56
The role of CD4⁺FoxP3⁺ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment	56
LncRNA FAM83A-AS1 facilitates tumor proliferation and the migration via the HIF-1α/ glycolysis axis in lung adenocarcinoma	56
Enolase 1, a Moonlighting Protein, as a Potential Target for Cancer Treatment	55
Targeting Ferroptosis as a Novel Approach to Alleviate Aortic Dissection	55
A Multiple-Hit Hypothesis Involving Reactive Oxygen Species and Myeloperoxidase Explains Clinical Deterioration and Fatality in COVID-19	54
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination	53
Role of hydrogen sulfide donors in cancer development and progression	53
ALKBH5/MAP3K8 axis regulates PD-L1+ macrophage infiltration and promotes hepatocellular carcinoma progression	53