OOIR: Observatory of International Research

Papers

(The median citation count of Reproductive Medicine and Biology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Oxidative stress and male infertility	87
The role of pituitary gonadotropins and intraovarian regulators in follicle development: A mini‐review	62
Assisted reproductive technology in Japan: A summary report for 2018 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology	37
Analysis of vaginal and endometrial microbiota communities in infertile women with a history of repeated implantation failure	36
Pre‐implantation genetic testing: Past, present, future	29
Pathophysiology of polycystic ovary syndrome revisited: Current understanding and perspectives regarding future research	28
How does the extent of fibrosis in adenomyosis lesions contribute to heavy menstrual bleeding?	24
Assisted reproductive technology in Japan: A summary report for 2020 by the ethics Committee of the Japan Society of obstetrics and gynecology	22
Hypoxia: Role of SIRT1 and the protective effect of resveratrol in ovarian function	20
Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology	20
Higher fibrotic content of endometriotic lesions is associated with diminished prostaglandin E2 signaling	19
Resveratrol enhanced mitochondrial recovery from cryopreservation‐induced damages in oocytes and embryos	16
A novel system based on artificial intelligence for predicting blastocyst viability and visualizing the explanation	16
Saturated fatty acids accelerate linear motility through mitochondrial ATP production in bull sperm	16
Changing prostaglandin E2 (PGE₂) signaling during lesional progression and exacerbation of endometriosis by inhibition of PGE₂ receptor EP2 and EP4	16
Mechanobiology of the female reproductive system	16
The prevalence of celiac disease in women with infertility—A systematic review with meta‐analysis	15
Exposure to cigarette smoke affects endometrial maturation including angiogenesis and decidualization	14
Histopathological evaluation of cesarean scar defect in women with cesarean scar syndrome	14
Ovarian tissue grafting: Lessons learnt from our experience with 55 grafts	14
Molecular basis of the morphogenesis of sperm head and tail in mice	14
Kisspeptin neurons as an integration center of reproductive regulation: Observation of reproductive function based on a new concept of reproductive regulatory nervous system	13
Effect of hypothyroidism and thyroid autoimmunity on the ovarian reserve: A systematic review and meta‐analysis	13
Clinical relevance of a newly developed endometrial receptivity test for patients with recurrent implantation failure in Japan	13
A controlled clinical trial comparing potent progestins, LNG‐IUS and dienogest, for the treatment of women with adenomyosis	13

Preimplantation genetic testing for aneuploidy and chromosomal structural rearrangement: A summary of a nationwide study by the Japan Society of Obstetrics and Gynecology	12
Prevalence, definition, and etiology of cesarean scar defect and treatment of cesarean scar disorder: A narrative review	12
Mitochondrial replacement by genome transfer in human oocytes: Efficacy, concerns, and legality	11
Assisted reproductive technique outcomes in patients with endometrioma undergoing sclerotherapy vs laparoscopic cystectomy: Prospective cross‐sectional study	11
A novel PCOS rat model and an evaluation of its reproductive, metabolic, and behavioral phenotypes	11
Occurrence of chronic endometritis in different types of human adenomyosis	11
A gene network of uterine luminal epithelium organizes mouse blastocyst implantation	11
Increased risk of obstetric complications in patients with adenomyosis: A narrative literature review	11
Effects of low energy availability on female reproductive function	10
Meta‐analysis of the embryo freezing transfer interval	10
Chromosomal copy number analysis of products of conception by conventional karyotyping and next‐generation sequencing	10
Transcriptomic profiling analysis of human endometrial stromal cells treated with autologous platelet‐rich plasma	10
Understanding the molecular mechanisms of macrophage polarization and metabolic reprogramming in endometriosis: A narrative review	10
The effect of repeated cryopreservation and thawing using cryotip on the clinical outcomes of embryos	10
Novel approaches to the management of recurrent pregnancy loss: The OPTIMUM (OPtimization of Thyroid function, Thrombophilia, Immunity, and Uterine Milieu) treatment strategy	10
Relationship between follicular size and developmental capacity of oocytes under controlled ovarian hyperstimulation in assisted reproductive technologies	10
Clinical outcome of intrauterine infusion of platelet‐rich plasma in patients with recurrent implantation failure	10
Three‐dimensional reconstruction of testis cords/seminiferous tubules	9
Single‐cell profiling of transcriptomic changes during in vitro maturation of human oocytes	9
3D reconstruction and histopathological analyses on murine corporal body	9
Loss of Axdnd1 causes sterility due to impaired spermatid differentiation in mice	9
An assessment of the efficacy and safety of dydrogesterone in women with ovarian endometrioma: An open‐label multicenter clinical study	9
Microbiome analysis in women with endometriosis: Does a microbiome exist in peritoneal fluid and ovarian cystic fluid?	9
Mosaic loss of the Y chromosome and men's health	9
Therapeutic effect of prolonged testosterone pretreatment in women with poor ovarian response: A randomized control trial	8
The impact of phthalate on reproductive function in women with endometriosis	8
CDX2 downregulation in mouse mural trophectoderm during peri‐implantation is heteronomous, dependent on the YAP‐TEAD pathway and controlled by estrogen‐induced factors	8
Fertility and sexual dysfunction in young male cancer survivors	8
Cumulative live birth rate according to the number of receiving governmental subsidies for assisted reproductive technology in Saitama Prefecture, Japan: A retrospective study using individual data fo	8
Endometrial polyps with increased plasma cells are associated with chronic endometritis in infertility patients: Hysteroscopic findings and post‐polypectomy pregnancy rates	8
Laser‐assisted hatching on clinical and neonatal outcomes in patients undergoing single vitrified Blastocyst transfer: A propensity score–matched study	8
Overview of single‐cell RNA sequencing analysis and its application to spermatogenesis research	8
Genetic counseling prior to assisted reproductive technology	8
Mitochondrial function of human embryo: Decline in their quality with maternal aging	8
The relationship of 4‐vinylcyclohexene diepoxide toxicity with cell death, oxidative stress, and gap junctions in female rat ovaries	7
A new deep‐learning model using YOLOv3 to support sperm selection during intracytoplasmic sperm injection procedure	7
Reorganization, specialization, and degradation of oocyte maternal components for early development	7
The Asian Society of Endometriosis and Adenomyosis guidelines for managing adenomyosis	7
The effects of differences in trophectoderm biopsy techniques and the number of cells collected for biopsy on next‐generation sequencing results	7
Impact of the one‐carbon metabolism on oocyte maturation, fertilization, embryo quality, and subsequent pregnancy	7
IVM of human immature oocytes for infertility treatment and fertility preservation	7
The impact of oocyte death on mouse primordial follicle formation and ovarian reserve	7
The possible effects of the Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 on the practice of fertility preservation in female cancer patients in Japan	6
A novel trophectoderm biopsy technique for all blastocyst stages	6
Corroborating evidence for aberrant expression of histone deacetylase 8 in endometriosis	6
Maca extracts and estrogen replacement therapy in ovariectomized rats exposed at high altitude	6
Effect of early rescue ICSI and split IVF‐ICSI in preventing low fertilization rate during the first ART cycle: A real‐world retrospective cohort study	6
Are tri‐pronuclear embryos that show two normal‐sized pronuclei and additional smaller pronuclei useful for embryo transfer?	6
Guidelines for Reproductive Medicine in Japan	6
Age‐dependent phenotypes of ovarian endometriomas	5

Efficacy of cyclic and extended regimens of ethinylestradiol 0.02 mg ‐levonorgestrel 0.09 mg for dysmenorrhea: A placebo‐controlled, double‐blind, randomized trial	5
Clinicopathological characteristics and imaging findings to identify adenomyosis‐related symptoms	5
Paracrine regulation of granulosa cell development in the antral follicles in mammals	5
Clinical efficacy of dual trigger with human chorionic gonadotropin and a gonadotropin‐releasing hormone agonist for women undergoing fertility preservation	5
Sex difference in anti‐sperm antibodies	5
IGF‐I and NGFβ enhance in vitro progressive motility and vitality of human spermatozoa	5
Improved developmental potential of mouse vitrified‐warmed oocytes achieved by culturing in recovery medium with glutathione ethyl ester (GSH‐OEt)	5
NDRG1 is expressed in human granulosa cells: An implicative role of NDRG1 in the ovary	5
Male advantage observed for in vitro fertilization mouse embryos exhibiting early cleavage	5
Sphingosine kinases negatively regulate the expression of matrix metalloproteases (MMP1 and MMP3) and their inhibitor TIMP3 genes via sphingosine 1‐phosphate in extravillous troph	5
Therapeutic efficacy of the optimization of thyroid function, thrombophilia, immunity and uterine milieu (OPTIMUM) treatment strategy on pregnancy outcomes after single euploid blastocyst t	5
Effects of post‐ovulatory aging on centromeric cohesin protection in murine MII oocytes	5
Indication of intravaginal insemination for infertility treatment in couples with sexual dysfunction	4
Influence of sperm cryopreservation on sperm motility and proAKAP4 concentration in mice	4
Adverse effect of lactobacilli‐depauperate cervicovaginal microbiota on pregnancy outcomes in women undergoing frozen–thawed embryo transfer	4
Genomic imprinting in human placentation	4
Usefulness of expanding the indications of early rescue intracytoplasmic sperm injection	4
The gonadotropins starting dose calculator, which can be adjusted the target number of oocytes and stimulation duration days to achieve individualized controlled ovarian stimulation in Japanese patien	4
Effects of aging and oviductal hormones on testes, epididymides, and sperm of hamster	4
Relation between semen oxidative reduction potential in initial semen examination and IVF outcomes	4
Therapeutic efficacy of gentle endometrial curettage on antibiotic‐resistant chronic endometritis in infertile women	4
Isolation and characterization of fetal nucleated red blood cells from maternal blood as a target for single cell sequencing‐based non‐invasive genetic testing	4
Usefulness of combined NGS and QF‐PCR analysis for product of conception karyotyping	4
Aneuploidy and sex concordance rate between cell‐free DNA analysis from spent culture media of preimplantation embryo and DNA from whole embryo with respect to different morpholo	4
TULP2 deletion mice exhibit abnormal outer dense fiber structure and male infertility	4
Genetic variants of G‐protein coupled receptors associated with pubertal disorders	4
How to improve the clinical outcome of round spermatid injection (ROSI) into the oocyte: Correction of epigenetic abnormalities	4
Status of online sperm donation and sperm bank in Japan	3
The expression of human testis‐specific actin capping protein predicts in vitro fertilization outcomes: A novel biomarker of sperm function for assisted reproductive technology	3
Exome‐based genome‐wide screening of rare variants associated with the risk of polycystic ovary syndrome	3
Differential expression of estrogen receptor subtypes in ovarian high‐grade serous carcinoma and clear cell carcinoma	3
The migration speed of nucleolar precursor bodies in pronuclei affects in vitro fertilization‐derived human embryo ploidy status and live birth	3
Pervasiveness of intronless genes expressed in haploid germ cell differentiation	3
Evaluation of NKp46 expression and cytokine production of decidual NK cells in women with recurrent pregnancy loss	3
Expression and co‐localization of RFRP‐3 and kisspeptin during breeding and non‐breeding season in the hypothalamus of male rhesus monkey (Macaca mulatta)	3
Analysis of clinical outcomes and meiotic segregation modes following preimplantation genetic testing for structural rearrangements using aCGH/NGS in couples with balanced chromo	3
Aberrant expression of histone deacetylase 8 in endometriosis and its potential as a therapeutic target	3
Therapeutic effects of an oral gonadotropin‐releasing hormone receptor antagonist, relugolix, on preventing premature ovulation in mild ovarian stimulation for IVF	3
Effect of transdermal estrogen dose regimen for endometrial preparation of frozen‐thawed embryo transfer on reproductive and obstetric outcomes	3
Prominin‐1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice	3
Follicular development during hormone replacement therapy in patients with premature ovarian insufficiency	3
A review of experimental techniques for erectile function researches and development of medical technology using animal erectile dysfunction models in sexual and reproductive medicine	3
Influence of a patient education and care program on women undergoing non‐assisted reproductive technology fertility treatment	3
The ratio of 2nd to 4th digit length and reproductive function of infertile male patients	3
Age‐ and endometrial microbiota‐related delay in development of endometrial receptivity	3
Establishment of mouse line showing inducible priapism‐like phenotypes	3
History and prospects of intracytoplasmic sperm injection (ICSI) and the development of golden hamster ICSI embryos	3
Are the body shape index, the body roundness index and waist‐to‐hip ratio better than BMI to predict recurrent pregnancy loss?	3
Sperm immobilization test and quantitative sperm immobilization test using frozen‐thawed sperm preparation applied with computer‐aided sperm analysis	3
Follicle development and its prediction in patients with primary ovarian insufficiency: Possible treatments and markers to maximize the ability to conceive with residual follicles	3
Expression of RSPH6A in the first wave of rat spermatogenesis and oxidative stress conditions: Attenuation by melatonin	2
Neurological development in 36‐month‐old children conceived via assisted reproductive technology: The Japan Environment and Children's Study	2
Assisted reproductive technology in Japan: A summary report for 2021 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology	2
Hormonal support in women with Asherman syndrome does not lead to better outcomes: A randomized trial	2
Short‐term efficacy and safety of early medical abortion in Japan: A multicenter prospective study	2
Chances of pregnancy after dropping out from infertility treatments: Evidence from a social survey in Japan	2
Improvement of oocyte quality through the SIRT signaling pathway	2
Creation, effects on embryo quality, and clinical outcomes of a new embryo culture medium with 31 optimized components derived from human oviduct fluid: A prospective multicenter randomized trial	2
Chromosomal analyses of human giant diploid oocytes by next‐generation sequencing	2
High concentration of dopamine treatment may induce acceleration of human sperm motility	2
Impact of abnormal karyotype on reproductive outcome in premature ovarian insufficiency	2
Fatty acid supplementation into warming solutions improves pregnancy outcomes after single vitrified‐warmed cleavage stage embryo transfers	2
Gonadotropin levels at the start of ovarian stimulation predict normal fertilization after hCG re‐trigger in GnRH antagonist cycles	2
Swim‐up method is superior to density gradient centrifugation for preserving sperm DNA integrity during sperm processing	2
Decrease in serum anti‐Müllerian hormone level per puncture with laparoscopic ovarian drilling using ultrasonically activated device	2
d‐Leucine protects oocytes from chronic psychological stress in mice	2
microRNAs associated with the quality of follicular fluids affect oocyte and early embryonic development	2
Time from trophectoderm biopsy to vitrification affects the developmental competence of biopsied blastocysts	2
Shallow artificial networks with morphokinetic time‐lapse parameters coupled to ART data allow to predict live birth	2
Effect of docosahexaenoic acid on in vitro growth of bovine oocytes	2
Embryos, cancers, and parasites: Potential applications to the study of reproductive biology in view of their similarity as biological phenomena	2
DNA damage in human sperm: The sperm chromosome assay	2