OOIR: Observatory of International Research

Papers

(The median citation count of Reproductive Medicine and Biology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Endocrine‐disrupting chemicals and male reproductive health	78
Oxidative stress and male infertility	70
The role of pituitary gonadotropins and intraovarian regulators in follicle development: A mini‐review	45
Assisted reproductive technology in Japan: A summary report for 2018 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology	35
Extra‐pelvic endometriosis: A review	32
Analysis of vaginal and endometrial microbiota communities in infertile women with a history of repeated implantation failure	29
Mesenchymal stem cells for restoring endometrial function: An infertility perspective	28
Genetic disorders and male infertility	27
Pre‐implantation genetic testing: Past, present, future	21
Resveratrol protects mitochondrial quantity by activating SIRT1/PGC‐1α expression during ovarian hypoxia	20
Intrauterine administration of platelet‐rich plasma improves embryo implantation by increasing the endometrial thickness in women with repeated implantation failure: A single‐arm self‐controlled trial	19
Hypoxia: Role of SIRT1 and the protective effect of resveratrol in ovarian function	17
How does the extent of fibrosis in adenomyosis lesions contribute to heavy menstrual bleeding?	16
Pathophysiology of polycystic ovary syndrome revisited: Current understanding and perspectives regarding future research	15
Higher fibrotic content of endometriotic lesions is associated with diminished prostaglandin E2 signaling	15
Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology	15
Evaluation of the effect of piezo‐intracytoplasmic sperm injection on the laboratory, clinical, and neonatal outcomes	14
Ovarian reserve after three‐step laparoscopic surgery for endometriomas utilizing dienogest: A pilot study	13
Saturated fatty acids accelerate linear motility through mitochondrial ATP production in bull sperm	13
The regulation of trophoblast invasion and decidual reaction by matrix metalloproteinase‐2, metalloproteinase‐7, and metalloproteinase‐9 expressions in the rat endometrium	12
Mitochondrial replacement by genome transfer in human oocytes: Efficacy, concerns, and legality	11
A novel PCOS rat model and an evaluation of its reproductive, metabolic, and behavioral phenotypes	11
The prevalence of celiac disease in women with infertility—A systematic review with meta‐analysis	11
Assisted reproductive technology in Japan: A summary report for 2020 by the ethics Committee of the Japan Society of obstetrics and gynecology	11
Mechanobiology of the female reproductive system	11

Histopathological evaluation of cesarean scar defect in women with cesarean scar syndrome	10
Clinical relevance of a newly developed endometrial receptivity test for patients with recurrent implantation failure in Japan	10
Assisted reproductive technique outcomes in patients with endometrioma undergoing sclerotherapy vs laparoscopic cystectomy: Prospective cross‐sectional study	10
Trophoblast lineage specification in the mammalian preimplantation embryo	10
Increased risk of obstetric complications in patients with adenomyosis: A narrative literature review	10
Changing prostaglandin E2 (PGE₂) signaling during lesional progression and exacerbation of endometriosis by inhibition of PGE₂ receptor EP2 and EP4	10
A gene network of uterine luminal epithelium organizes mouse blastocyst implantation	10
Effect of hypothyroidism and thyroid autoimmunity on the ovarian reserve: A systematic review and meta‐analysis	10
Novel approaches to the management of recurrent pregnancy loss: The OPTIMUM (OPtimization of Thyroid function, Thrombophilia, Immunity, and Uterine Milieu) treatment strategy	9
Unique features and emerging in vitro models of human placental development	9
Abundance of cell‐free mitochondrial DNA in spent culture medium associated with morphokinetics and blastocyst collapse of expanded blastocysts	9
Effects of low energy availability on female reproductive function	9
Meta‐analysis of the embryo freezing transfer interval	9
Ovarian tissue grafting: Lessons learnt from our experience with 55 grafts	9
Resveratrol enhanced mitochondrial recovery from cryopreservation‐induced damages in oocytes and embryos	9
Exposure to cigarette smoke affects endometrial maturation including angiogenesis and decidualization	9
Chromosomal copy number analysis of products of conception by conventional karyotyping and next‐generation sequencing	8
3D reconstruction and histopathological analyses on murine corporal body	8
A novel system based on artificial intelligence for predicting blastocyst viability and visualizing the explanation	8
Clinical outcome of intrauterine infusion of platelet‐rich plasma in patients with recurrent implantation failure	8
A controlled clinical trial comparing potent progestins, LNG‐IUS and dienogest, for the treatment of women with adenomyosis	8
Cumulative live birth rate according to the number of receiving governmental subsidies for assisted reproductive technology in Saitama Prefecture, Japan: A retrospective study using individual data fo	8
Kisspeptin neurons as an integration center of reproductive regulation: Observation of reproductive function based on a new concept of reproductive regulatory nervous system	8
Microbiome analysis in women with endometriosis: Does a microbiome exist in peritoneal fluid and ovarian cystic fluid?	7
Three‐dimensional reconstruction of testis cords/seminiferous tubules	7
Relationship between follicular size and developmental capacity of oocytes under controlled ovarian hyperstimulation in assisted reproductive technologies	7
Testicular volume in non‐obstructive azoospermia with a history of bilateral cryptorchidism may predict successful sperm retrieval by testicular sperm extraction	7
Endometrial polyps with increased plasma cells are associated with chronic endometritis in infertility patients: Hysteroscopic findings and post‐polypectomy pregnancy rates	7
Therapeutic effect of prolonged testosterone pretreatment in women with poor ovarian response: A randomized control trial	7
Genetic counseling prior to assisted reproductive technology	7
An assessment of the efficacy and safety of dydrogesterone in women with ovarian endometrioma: An open‐label multicenter clinical study	7
The effect of repeated cryopreservation and thawing using cryotip on the clinical outcomes of embryos	7
Development of an automated two pronuclei detection system on time‐lapse embryo images using deep learning techniques	7
Effects of estradiol on in vitro maturation of buffalo and goat oocytes	7
Single‐cell profiling of transcriptomic changes during in vitro maturation of human oocytes	7
Molecular basis of the morphogenesis of sperm head and tail in mice	7
Occurrence of chronic endometritis in different types of human adenomyosis	7
Effect of equilibration time on clinical and neonatal outcomes in human blastocysts vitrification	7
Predictive factors influencing pregnancy rate in frozen embryo transfer	6
Maca extracts and estrogen replacement therapy in ovariectomized rats exposed at high altitude	6
Improvement of early developmental competence of postovulatory‐aged oocytes using metaphase II spindle injection in mice	6
The impact of endometrial injury on reproductive outcomes: results of an updated meta‐analysis	6
The effects of differences in trophectoderm biopsy techniques and the number of cells collected for biopsy on next‐generation sequencing results	6
Laser‐assisted hatching on clinical and neonatal outcomes in patients undergoing single vitrified Blastocyst transfer: A propensity score–matched study	6
The impact of phthalate on reproductive function in women with endometriosis	6
Preimplantation genetic testing for aneuploidy and chromosomal structural rearrangement: A summary of a nationwide study by the Japan Society of Obstetrics and Gynecology	6
Effect of early rescue ICSI and split IVF‐ICSI in preventing low fertilization rate during the first ART cycle: A real‐world retrospective cohort study	6
Sphingosine kinases negatively regulate the expression of matrix metalloproteases (MMP1 and MMP3) and their inhibitor TIMP3 genes via sphingosine 1‐phosphate in extravillous troph	5
Fertility and sexual dysfunction in young male cancer survivors	5
The possible effects of the Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 on the practice of fertility preservation in female cancer patients in Japan	5

Cutting the ovarian surface improves the responsiveness to exogenous hormonal treatment in aged mice	5
Improved developmental potential of mouse vitrified‐warmed oocytes achieved by culturing in recovery medium with glutathione ethyl ester (GSH‐OEt)	5
Understanding the molecular mechanisms of macrophage polarization and metabolic reprogramming in endometriosis: A narrative review	5
Clinicopathological characteristics and imaging findings to identify adenomyosis‐related symptoms	5
Impact of subchorionic hematoma in early pregnancy on obstetric complications: A retrospective cohort study in women who had live births after frozen‐thawed embryo transfer	5
Relationship between nutrition and reproduction	5
Loss of Axdnd1 causes sterility due to impaired spermatid differentiation in mice	4
The impact of oocyte death on mouse primordial follicle formation and ovarian reserve	4
Absence of laws regarding sperm and oocyte donation in Japan and the impacts on donors, parents, and the people born as a result	4
Efficacy of cyclic and extended regimens of ethinylestradiol 0.02 mg ‐levonorgestrel 0.09 mg for dysmenorrhea: A placebo‐controlled, double‐blind, randomized trial	4
Reorganization, specialization, and degradation of oocyte maternal components for early development	4
Transcriptomic profiling analysis of human endometrial stromal cells treated with autologous platelet‐rich plasma	4
A new deep‐learning model using YOLOv3 to support sperm selection during intracytoplasmic sperm injection procedure	4
Mitochondrial function of human embryo: Decline in their quality with maternal aging	4
Usefulness of expanding the indications of early rescue intracytoplasmic sperm injection	4
Male advantage observed for in vitro fertilization mouse embryos exhibiting early cleavage	4
CDX2 downregulation in mouse mural trophectoderm during peri‐implantation is heteronomous, dependent on the YAP‐TEAD pathway and controlled by estrogen‐induced factors	4
pH variation impacts molecular pathways associated with somatic cell reprogramming and differentiation of pluripotent stem cells	4
NDRG1 is expressed in human granulosa cells: An implicative role of NDRG1 in the ovary	4
Mosaic loss of the Y chromosome and men's health	4
Relation between semen oxidative reduction potential in initial semen examination and IVF outcomes	4
A novel trophectoderm biopsy technique for all blastocyst stages	4
Isolation and characterization of fetal nucleated red blood cells from maternal blood as a target for single cell sequencing‐based non‐invasive genetic testing	4
Copy‐number analysis of Y‐linked loci in young men with non‐obstructive azoospermia: Implications for the rarity of early onset mosaic loss of chromosome Y	3
Sex difference in anti‐sperm antibodies	3
Age‐ and endometrial microbiota‐related delay in development of endometrial receptivity	3
Effects of aging and oviductal hormones on testes, epididymides, and sperm of hamster	3
Guidelines for Reproductive Medicine in Japan	3
Pervasiveness of intronless genes expressed in haploid germ cell differentiation	3
History and prospects of intracytoplasmic sperm injection (ICSI) and the development of golden hamster ICSI embryos	3
Risk factors of subclinical hypothyroidism and the potential contribution to miscarriage: A review	3
Analysis of clinical outcomes and meiotic segregation modes following preimplantation genetic testing for structural rearrangements using aCGH/NGS in couples with balanced chromo	3
Influence of sperm cryopreservation on sperm motility and proAKAP4 concentration in mice	3
Differential expression of estrogen receptor subtypes in ovarian high‐grade serous carcinoma and clear cell carcinoma	3
Impact of the one‐carbon metabolism on oocyte maturation, fertilization, embryo quality, and subsequent pregnancy	3
Follicular development during hormone replacement therapy in patients with premature ovarian insufficiency	3
Evaluation of NKp46 expression and cytokine production of decidual NK cells in women with recurrent pregnancy loss	3
Indication of intravaginal insemination for infertility treatment in couples with sexual dysfunction	3
IGF‐I and NGFβ enhance in vitro progressive motility and vitality of human spermatozoa	3
How to improve the clinical outcome of round spermatid injection (ROSI) into the oocyte: Correction of epigenetic abnormalities	3
Overview of single‐cell RNA sequencing analysis and its application to spermatogenesis research	3
Are tri‐pronuclear embryos that show two normal‐sized pronuclei and additional smaller pronuclei useful for embryo transfer?	2
The relationship of 4‐vinylcyclohexene diepoxide toxicity with cell death, oxidative stress, and gap junctions in female rat ovaries	2
Chromosomal analyses of human giant diploid oocytes by next‐generation sequencing	2
Effect of docosahexaenoic acid on in vitro growth of bovine oocytes	2
Chances of pregnancy after dropping out from infertility treatments: Evidence from a social survey in Japan	2
Embryos, cancers, and parasites: Potential applications to the study of reproductive biology in view of their similarity as biological phenomena	2
The ratio of 2nd to 4th digit length and reproductive function of infertile male patients	2
TULP2 deletion mice exhibit abnormal outer dense fiber structure and male infertility	2
Genomic imprinting in human placentation	2
Paracrine regulation of granulosa cell development in the antral follicles in mammals	2
Therapeutic efficacy of the optimization of thyroid function, thrombophilia, immunity and uterine milieu (OPTIMUM) treatment strategy on pregnancy outcomes after single euploid blastocyst t	2
Usefulness of combined NGS and QF‐PCR analysis for product of conception karyotyping	2
IVM of human immature oocytes for infertility treatment and fertility preservation	2
A review of experimental techniques for erectile function researches and development of medical technology using animal erectile dysfunction models in sexual and reproductive medicine	2
Age‐dependent phenotypes of ovarian endometriomas	2
The gonadotropins starting dose calculator, which can be adjusted the target number of oocytes and stimulation duration days to achieve individualized controlled ovarian stimulation in Japanese patien	2
The impact of parental unaffected allele combination on the diagnostic outcome in the preimplantation genetic testing for myotonic dystrophy type 1 in Japanese ancestry	2
Exome‐based genome‐wide screening of rare variants associated with the risk of polycystic ovary syndrome	2
Usefulness of modified Medium RD as a chemically defined medium for in vitro maturation of bovine oocytes	2
Genetic variants of G‐protein coupled receptors associated with pubertal disorders	2
Corroborating evidence for aberrant expression of histone deacetylase 8 in endometriosis	2
Clinical efficacy of dual trigger with human chorionic gonadotropin and a gonadotropin‐releasing hormone agonist for women undergoing fertility preservation	2
Are the body shape index, the body roundness index and waist‐to‐hip ratio better than BMI to predict recurrent pregnancy loss?	2
The Asian Society of Endometriosis and Adenomyosis guidelines for managing adenomyosis	2
Impact of abnormal karyotype on reproductive outcome in premature ovarian insufficiency	2
Sperm immobilization test and quantitative sperm immobilization test using frozen‐thawed sperm preparation applied with computer‐aided sperm analysis	2
Status of online sperm donation and sperm bank in Japan	2
Prevalence, definition, and etiology of cesarean scar defect and treatment of cesarean scar disorder: A narrative review	2
Adverse effect of lactobacilli‐depauperate cervicovaginal microbiota on pregnancy outcomes in women undergoing frozen–thawed embryo transfer	2
Therapeutic effects of an oral gonadotropin‐releasing hormone receptor antagonist, relugolix, on preventing premature ovulation in mild ovarian stimulation for IVF	2
DNA damage in human sperm: The sperm chromosome assay	2
Prominin‐1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice	2