OOIR: Observatory of International Research

Papers

(The TQCC of Modern Rheumatology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Comparison between the BioPlex 2200 ANA Screen™ and a conventional method with respect to the detection of autoantibodies	87
The serum immunoglobulin G titres against Porphyromonas gingivalis as a predictor of clinical response to 1-year treatment with biological disease-modifying antirheumatic drugs in rheumatoid ar	38
Characteristics of patients presenting with concomitant carpal tunnel syndrome at the initial diagnosis with rheumatoid arthritis	29
Safety and effectiveness of sarilumab in Japanese patients with rheumatoid arthritis refractory to previous treatments: An interim analysis of a post-marketing surveillance	27
Changes in treatment adherence and behaviour during the COVID-19 pandemic in Japanese patients with rheumatoid arthritis: Results from cross-sectional study in the IORRA cohort	27
The effectiveness and safety of subcutaneous methotrexate injection in Japanese patients with rheumatoid arthritis in a real-world setting	26
Antiphospholipid antibody positivity and the thrombotic risk in Japanese patients with anti-neutrophil cytoplasmic antibody-associated vasculitis	26
1 mg/day or 10 mg/week? Folic acid supplementation with methotrexate in rheumatoid arthritis	25
Correction to: Long-term safety and efficacy of belimumab in Japanese patients with SLE: A 7-year open-label continuation study	24
Consideration of useful patient-reported outcome measures to identify the unmet medical needs of children and adults with autoimmune and autoinflammatory diseases	24
The dietary acid load is associated with disease severity in psoriatic arthritis	23
Expert perspectives on pathological findings in vasculitis	22
The trends in the prevalence of arthritis and arthralgia and their associations with extra-articular manifestations in patients with Behcet’s disease: A systematic review and meta-analysis	20
Real-world safety and effectiveness of mepolizumab for patients with eosinophilic granulomatosis with polyangiitis in Japan: A 48-week interim analysis of the MARS study	20
IL-18 receptor-α signalling pathway contributes to autoantibody-induced arthritis via neutrophil recruitment and mast cell activation	19
Management of patients with inflammatory rheumatic diseases after treatment failure with a first tumour necrosis factor inhibitor: A narrative review	19
COVID-19 in familial Mediterranean fever: Clinical course and complications related to primary disease	17
Safety and efficacy of switching immunosuppressive drugs for maintenance treatment in patients with systemic lupus erythematosus: A retrospective cohort study	16
Correction to: Risk of hospitalized infections in older elderly patients with rheumatoid arthritis treated with tocilizumab or other biological/targeted synthetic disease-modifying antirheumatic drugs	16
Gut microbiota-immune axis in the regulation of rheumatoid arthritis: from mechanism to precision probiotic strategies	15
Rheumatoid factor value for determining the first biologic agent to use for non-systemic juvenile idiopathic arthritis	15
Assessing the efficacy of haemoperfusion for dermatomyositis-associated acute exacerbation of interstitial lung disease: A multicentre retrospective study	15
Illustrations of rheumatoid arthritis symptoms to promote communication between patients and physicians	15
Development and validation of case-finding algorithms for identifying patients with systemic lupus erythematosus in an administrative claim database from tertiary care centers in Japan	14
Efficacy of anifrolumab in systemic lupus erythematosus patients with serological manifestations: A post hoc analysis of the Japan subgroup of the TULIP-2 trial	14

The bioimpedance phase angle may be associated with frailty in rheumatoid arthritis patients: Results from a prospective, cohort study	14
Similarity and difference between systemic lupus erythematosus and NZB/W F1 mice by multi-omics analysis	14
Effectiveness and safety of tocilizumab, an anti–interleukin-6 receptor antibody, in 342 Japanese patients with multicentric Castleman disease: a 3-year, prospective, observational study	14
Prevalence of social frailty in patients with rheumatoid arthritis: Data from a multicentre observational study (T-FLAG study)	13
Comparison of safety and effectiveness between etanercept biosimilar LBEC0101 and reference in patients with rheumatoid arthritis in real-world data using the KURAMA cohort	13
Early full weight-bearing and gait exercise after cemented total ankle arthroplasty with a modified anterolateral approach	13
Association between the timing of intravenous immunoglobulin treatment and severity of Kawasaki disease	12
Age-related differences in the clinical phenotypes of Behçet’s disease: The experience of two referral centres	12
Differences in the autoantibody phenotypes and long-term outcomes between juvenile- and adult-onset systemic sclerosis	12
Subcutaneous administration of methotrexate in children with paediatric rheumatic diseases	12
Predictors of damage accrual in patients with antineutrophil cytoplasmic antibody–associated vasculitis: A nationwide prospective study	11
Can the affected intestinal segment visualized on abdominal ultrasound predict gastrointestinal tract bleeding in immunoglobulin A vasculitis?	11
Investigating the subchondral trabecular bone microstructure in patients with osteonecrosis of the femoral head using multi-detector row computed tomography	11
Contribution of the factors to EuroQol 5 Dimensions in rheumatoid arthritis patients achieving low disease activity/remission with abatacept treatment: Post hoc subgroup analyses of the Japanes	11
VE-cadherin may suppress inflammation depending on the phase of inflammation of rheumatoid arthritis	11
Effectiveness and safety of low-energy shock wave therapy for digital ulcers associated with systemic sclerosis: A Phase 3 pivotal clinical trial	10
The aberrant levels of decorin induce damages of human salivary gland epithelial cells and polarization of macrophages	10
Reasons and risk factors for discontinuation of treatment with any biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: A long-term observational study	10
Heating of the neck or elbows alleviates Raynaud’s phenomenon but has different effects on different types of patients with systemic sclerosis	10
Evaluation of Ministry of Health, Labour and Welfare diagnostic criteria for antineutrophil cytoplasmic antibody–associated vasculitis compared to ACR/EULAR 2022 classification criteria	10
Questionnaire survey on the prevention and development of cervical cancer in patients with systemic lupus erythematosus in Japan	10
Impact of ongoing glucocorticoid use on postoperative complications following total knee arthroplasty: a Japanese nationwide propensity score–matched cohort study	9
Risk factors for denosumab discontinuation in patients with postmenopausal osteoporosis	9
Associations of disease duration and anti-citrullinated peptide antibody status with the effectiveness of abatacept in biologic-naïve patients with rheumatoid arthritis: Post hoc analysis of a	9
Real-world treatment of gout and asymptomatic hyperuricaemia in Japan	9
Inflammation markers as risk factors for hypertension in primary Sjögren’s syndrome	9
Diagnostic values and relevant factors of lumbar posterior lesions in axial spondyloarthritis	9
Comparison of effectiveness of methotrexate in patients with late-onset versus younger-onset rheumatoid arthritis: Real-world data from an inception cohort in Japan (NICER-J)	9
Safety and effectiveness of ixekizumab in Japanese patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis in real-world use: a post-marketing safety study	9
Analysis of the saliva microbiome in patients with immunoglobulin G4–related disease	9
Successful treatment of systemic lupus erythematosus with residual disease activity by switching from belimumab to anifrolumab	9
Effectiveness of tacrolimus concomitant with biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis	9
Pearls and pitfalls in imaging of axial spondyloarthritis for rheumatologists	8
The role of ultrasound and FDG-PET/CT to detect extracranial artery involvement in patients with suspected large vessel vasculitis	8
Structural, nonclinical, and clinical features of ozoralizumab: A novel tumour necrosis factor inhibitor	8
Central sensitization in axial spondyloarthritis: An explorative study with quantitative sensory testing and clinical scales	8
Response to Dr Urata’s Letter to the Editor of Modern Rheumatology regarding a study of “Treatment of rheumatoid arthritis after regression of lymphoproliferative disorders”	8
Significant association of HLA-A26 with uveitis and gastrointestinal involvement in patients with Behçet’s disease in a multicentre study	8
Prognostic nutritional index as an indicator for the development of bone fragility fracture in patients with rheumatoid arthritis	8
A unified serum IgG4 cut-off level for the diagnosis of IgG4-related disease using a wide array of kits	8
Validation of the 2019 EULAR/ACR classification criteria and clinical characteristics of childhood-onset Japanese patients with systemic lupus erythematosus	8
High plasma homocysteine level is associated with increased prevalence of the non-remission state in rheumatoid arthritis: Findings from the KURAMA cohort	8
Validation of the MCK model for predicting outcomes in myopathy-associated interstitial lung disease: a multicentre MYKO cohort study	8
Long-term safety and efficacy of filgotinib treatment for rheumatoid arthritis in Japanese patients naïve to MTX treatment (FINCH 3)	8
Predictive factors for achievement of treatment goals in patients with postmenopausal osteoporosis treated with denosumab	8
Three-year safety and effectiveness of tofacitinib in patients with rheumatoid arthritis in Japan: Final analysis of an all-case postmarketing surveillance study	8
Assessment of muscle quality and quantity in individuals with diffuse idiopathic skeletal hyperostosis	8
Drug-survival profiling of second-line biologic therapy in rheumatoid arthritis: Choice of another tumour necrosis factor inhibitor or a biologic of different mode of action?	7
Characteristics of patients with polymyalgia rheumatica based on glucocorticoid dose in Japan: A cohort study using routinely collected health data	7
Efficacy and safety of febuxostat in Japanese paediatric patients with hyperuricaemia including gout: Phase 2, single arm, open‒label, multicentre studies	7

Kynurenine pathway of tryptophan metabolism in patients with familial Mediterranean fever	7
Severity scores, damage indices, and the concept of the colchicine-resistant patient in familial Mediterranean fever	7
A clinical overview of paediatric sarcoidosis: Multicentre experience from Turkey	7
Prevalence of high and low serum alkaline phosphatase levels and the associated factors in patients with rheumatoid arthritis: Results from the IORRA cohort study	7
Safety and effectiveness of peficitinib 100 mg/day in patients achieving clinical remission from a long-term open-label extension study in Japan, Korea, and Taiwan (RAJ2)	7
The efficacy and safety of anifrolumab in Japanese patients with systemic lupus erythematosus: TULIP-2 subanalysis	7
Efficacy and safety of anakinra for acute calcium pyrophosphate deposition disease flare: a systematic review and meta-analysis	7
Feasibility and applicability of locomotive syndrome risk test in elderly patients who underwent total knee arthroplasty	7
Severe COVID-19 in patients with immune-mediated rheumatic diseases: A stratified analysis from the SORCOM multicentre registry	7
Non-B27 HLA-B alleles lack diagnostic value, necessitating composite clinical indices to distinguish axial spondyloarthritis from radiographic mimics in Japanese patients	7
Mortality and risk factors in Japanese patients with rheumatoid arthritis: a 14-year observation of the IORRA cohort	7
Treatment of rheumatoid arthritis after regression of lymphoproliferative disorders in patients treated with methotrexate: A retrospective, multi-center descriptive study: Comment on the article by Na	7
Telemedicine for paediatric rheumatic diseases in Japan: a national survey of physicians’ perspectives	7
Elucidation of factors influencing spinal ankylosis in patients with axial spondyloarthritis	7
Elevated serum heparin-binding protein levels in patients with gout flare	6
Evaluation of articular cartilage degeneration in patients with osteonecrosis of the femoral head using T2 mapping magnetic resonance imaging	6
Factors associated with osteoporosis and fractures in patients with systemic lupus erythematosus: Kyoto Lupus Cohort	6
Comprehensive assessment of patients with symptomatic hand osteoarthritis: Cross-sectional insights into links with other joints	6
Predictors of disease course in systemic juvenile idiopathic arthritis	6
Comparisons between US norm-based two-component and Japanese norm-based three-component SF-36 summary scores in systemic lupus erythematosus patients	6
Antibody response to SARS-CoV-2 mRNA vaccines in patients with rheumatic diseases in Japan: Interim analysis of a multicentre cohort study	6
Prevalence, patient characteristics and treatment patterns among systemic lupus erythematosus–pulmonary arterial hypertension patients in real-world clinical practice: A retrospective analysis of Medi	6
Gender differences in patient experience in idiopathic inflammatory myopathies: Subanalysis from the COVAD dataset	6
Symptoms compatible with Rome IV functional bowel disorder in patients with ankylosing spondylitis	6
Neck pain and related factors in patients with rheumatoid arthritis	6
Laboratory markers predicting tofacitinib efficacy in Japanese patients with rheumatoid arthritis: A pooled analysis of Phase 2/3 randomised controlled clinical trials	6
The relationship between locomotive syndrome and depression in young Chinese college students	6
Radiographic study of the distal ulna in rheumatoid arthritis with extensor digitorum communis ruptures	6
Safety and effectiveness of certolizumab pegol in Japanese patients with rheumatoid arthritis: Results from a 24-week post-marketing surveillance study	6
Management review of scleroderma renal crisis: An update with practical pointers	6
Association of bisphosphonate with bone loss and pain-related behaviour in an adjuvant-induced osteoporosis model	6
Non-infectious uveitis referred for pediatric rheumatologic assessment and management: A Portuguese retrospective study	6
Verification of unmet medical needs in patients with juvenile idiopathic arthritis in Japan	6
Gene regulatory network study of rheumatoid arthritis in single-cell chromatin landscapes of peripheral blood mononuclear cells	6
A multicentre study of clinical features and HLA typing in Japanese patients with ankylosing spondylitis	5
Factors associated with frailty in rheumatoid arthritis patients with decreased renal function	5
Risk factor analysis of vertebral fractures requiring surgery in patients with ankylosing spondylitis	5
The need for telemedicine for rheumatic diseases in adult medical care: a survey of nonpaediatric rheumatologists	5
Relationship between the phase angle from bioelectrical impedance analysis and daily physical activity in patients with rheumatoid arthritis	5
Grip Strength Asymmetry as a Better Indicator of Residual Hand Symptoms than Absolute Grip Strength After Achieving Treat-To-Target in Rheumatoid Arthritis	5
Prognostic factors affecting respiratory-related death in patients with rheumatoid arthritis complicated by interstitial lung disease: An ANSWER cohort study	5
A Multicentre, Prospective Registry of Patients with Systemic Sclerosis in Japan: Baseline Patient Characteristics	5
Differences in sex- and age-associated mortality in patients with anti-MDA5-positive dermatomyositis	5
Romosozumab increases bone mineral density in Japanese older adults with osteoporosis	5
Frozen shoulder. An overview of pathology and biology with hopes to novel drug therapies	5
Challenges nurses face in providing care to older patients with rheumatoid arthritis: A qualitative study	5
Association of denosumab with serum cytokines, chemokines, and bone-related factors in patients with rheumatoid arthritis: A post hoc analysis of a multicentre, open-label, randomised, parallel	5
Clinical profile and outcome of large-vessel giant cell arteritis in Japanese patients: A single-centre retrospective cohort study	5
Iguratimod versus salazosulfapyridine in rheumatoid arthritis patients with an inadequate response to methotrexate: Adjusted with propensity score matching	5
Association of spinal ankylosis with spinal mobility and functional impairment in radiographic axial spondyloarthritis: A computed tomography study	5
A multicentre, large-scale, observational study of tocilizumab in patients with giant cell arteritis in Japan	5
Polypharmacy prevalence and associated factors in patients with systemic lupus erythematosus: A single-centre, cross-sectional study	5
Assessment of the dorsal tangent of the metacarpal neck as an intraoperative reference for metacarpophalangeal joint arthroplasty	5
PREDICT-crFMF score: A novel model for predicting colchicine resistance in children with familial Mediterranean fever	5
Impact of pain in other body regions on the foot-specific quality of life in patients with hallux valgus	5
Risk of hospitalized infections in older elderly patients with rheumatoid arthritis treated with tocilizumab or other biological/targeted synthetic disease-modifying antirheumatic drugs: Evaluation of	5
A retrospective, longitudinal study of rheumatoid arthritis treatment patterns with Janus kinase inhibitors and other disease-modifying antirheumatic drugs in Japan	5
Cardiac magnetic resonance imaging analysis of cardiac involvement in eosinophilic granulomatosis with polyangiitis	5
Challenges nurses face in providing care for patients with juvenile idiopathic arthritis	5
Risk factors for cytomegalovirus reactivation during the treatment of ANCA-associated vasculitis: A retrospective cohort study of the J-CANVAS study	5
Intervertebral fusion sites in patients with ankylosing spondylitis: A computed tomography study	5
Cut-off values for achieving osteoporosis treatment goals in women with rheumatoid arthritis receiving denosumab	5