Functional & Integrative Genomics

Papers
(The median citation count of Functional & Integrative Genomics is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
The complete plastid genome and characteristics analysis of Achillea millefolium440
Interplay of calcium signaling and ERF-VII stability in plant hypoxia tolerance171
RNA sequencing in Artemisia annua L explored the genetic and metabolic responses to hardly soluble aluminum phosphate treatment101
Major regulators of the multi-step metastatic process are potential therapeutic targets for breast cancer management73
Exploring circular RNAs as biomarkers for Parkinson’s disease and their expression changes after aerobic exercise rehabilitation72
mmu-microRNA-92a-3p attenuates pulmonary fibrosis by modulating Cpeb4-mediated Smad2/3 signaling pathway66
Circ-IP6K2 suppresses tumor progression by modulating the miR-1292-5p/CAMK2N1 signal in clear cell renal cell carcinoma61
TFAP2A-regulated CRNDE enhances colon cancer progression and chemoresistance via RIPK3 interaction60
Identification of the STY13 gene family across the entire genome and an analysis of the essential function of GhSTY13-12 in cotton’s response to abiotic stress54
Nuclear integration of MYB36 and APX-1 genes impart heat tolerance in wheat49
CRISPR/Cas9 editing of wheat Ppd-1 gene homoeologs alters spike architecture and grain morphometric traits45
CmirC update 2024: a multi-omics database for clustered miRNAs42
Retraction Note: Molecular subtypes based on PANoptosis-related genes and tumor microenvironment infiltration characteristics in lower-grade glioma41
GABPB1 activates transcription of ITPR3 and EMT in OSCC progression40
Construction of a pancreatic cancer prediction model for oxidative stress-related lncRNA39
Integrative genomics and genetics from evolutionary insights to precision breeding in peanuts (Arachis Hypogaea L.)37
The impact of the Hedgehog signal pathway on the tumor immune microenvironment of gastric adenocarcinoma by integrated analysis of scRNA-seq and RNA-seq datasets37
Genomic insights into Rhizobium anhuiense IY2 isolated from Trifolium caudatum root nodules37
LncRNA-encoded peptides: the case of the lncRNA gene located downstream of EIN236
Epigenetic silencing of MSTN via m6A modification underlies the renoprotective effects of engineered MSC exosomes with RBM15 depletion in diabetic nephropathy35
Integrative genetic analysis reveals shared genetic architecture underlying coronary artery disease, CT-Defined coronary atherosclerosis, and cardiometabolic risk factors35
Erythrocyte miRNA-92a-3p interactions with PfEMP1 as determinants of clinical malaria34
Linking genomic and proteomic signatures to brain amyloid burden: insights from GR@ACE/DEGESCO34
Rice WRKY13 TF protein binds to motifs in the promoter region to regulate downstream disease resistance-related genes34
DUBR non-coding RNA regulates gene expression by affecting AP-1 enhancer accessibility33
Integrated multi-omics analysis reveals key molecular mechanisms underlying fibroproliferation and immune dysregulation in keloids33
Purifying selection drove the adaptation of mitochondrial genes along with correlation of gene rearrangements and evolutionary rates in two subfamilies of Whitefly (Insecta: Hemiptera)33
CircNOX4 promotes proliferation and resistance by regulating the hsa-miR-6884-5p/YWHAG Axis and ERK signaling pathway in cholangiocarcinoma33
Harnessing breeding and biotechnological innovations for global food security under climate change32
The resilient cotton plant: uncovering the effects of stresses on secondary metabolomics and its underlying molecular mechanisms32
A multi-scale graph frequency network for structural and functional region analysis in spatial transcriptomics32
Exploring the glycolytic cross-talk genes between inflammatory bowel disease and colorectal cancer31
Multi-omics approaches: transforming the landscape of natural product isolation31
CRISPR detection in metagenome-assembled genomes (MAGs) of coal mine31
RETRACTED ARTICLE: ITGA3 acts as a purity-independent biomarker of both immunotherapy and chemotherapy resistance in pancreatic cancer: bioinformatics and experimental analysis31
Dynamic cellular composition and immune landscape revealed by single-cell transcriptome profiling in a brain arteriovenous malformation30
Prediction of chemoresistance in ovarian cancer based on deep learning with pathological images28
MYC-driven TRIM27 upregulation promotes prostate cancer progression by enhancing CANX ubiquitination and activating PI3K/AKT signaling26
Regulatory dynamics of Nanog in chondrocyte dedifferentiation: role of KLF4/p53 and p38/AKT signaling26
IL-1R8 expression in DLBCL regulates NK cell recruitment and influences patient prognosis26
Identification and mechanistic analysis of shared biomarkers and pathogenesis in acute pancreatitis and sepsis based on differential gene expression and protein interaction networks25
Transcription factor Dp-1 knockdown downregulates thymidine kinase 1 expression to protect against proliferation and epithelial-mesenchymal transition in cervical cancer25
RETRACTED ARTICLE: Identification of biomarkers of hepatocellular carcinoma gene prognosis based on the immune-related lncRNA signature of transcriptome data24
CircDCAF6 promotes myoblast differentiation by inhibiting the ubiquitination of ACTC124
RETRACTED ARTICLE: Comparison of preoperative ultrasound and MRI in the diagnosis of microvascular invasion in hepatocellular carcinoma24
Cloning and functional analysis of the DXR gene and promoter region in Osmanthus fragrans var. semperflorens24
Iodine-125 seed inhibits proliferation and promotes apoptosis of cholangiocarcinoma cells by inducing the ROS/p53 axis23
Evolution of phenylalanine ammonia-lyase protein family from algae to angiosperm23
Lipid-lowering activity of mulberry seed unsaturated fatty acids: integrating network pharmacology and experimental validation22
A novel tRNA-derived fragment tRF-3023b suppresses inflammation in RAW264.7 cells by targeting Cul4a through NF-κB signaling22
Regulation of plant epigenetic memory in response to cold and heat stress: towards climate resilient agriculture22
Mulberry fruit repairs alcoholic liver injury by modulating lipid metabolism and the expression of miR-155 and PPARα in rats22
Integrated Nanopore and short-read RNA sequencing identifies dysregulation of METTL3- m6A modifications in endocrine therapy- sensitive and resistant breast cancer cells22
Mechanism of histone deacetylase HDAC2 in FOXO3-mediated trophoblast pyroptosis in preeclampsia22
Molecular and genetic insights into secondary metabolic regulation underlying insect-pest resistance in legumes22
Predicting skin melanoma progression via LAG-3, TIGIT and HAVCR222
RETRACTED ARTICLE: Xihuang pill facilitates glioma cell pyroptosis via the POU4F1/STAT3 axis21
Integrative analysis of circ_DLGAP4, lncRNA KCNQ1OT1, and the miR-9/SOX7 interaction network in chronic kidney disease progression: a case-control study21
Selenium deficiency is functionally linked with the molecular etiopathogenesis of necrotizing enterocolitis (NEC)21
Genomic dissection of terminal heat tolerance in synthetic hexaploid derived nested introgression libraries of wheat (Triticum aestivum L.)21
High-throughput sequencing: a breakthrough in molecular diagnosis for precision medicine21
Genome-wide analysis of zinc finger-homeodomain (ZF-HD) transcription factors in diploid and tetraploid cotton21
Double-stranded RNA mediated knockdown of sucrase gene induced mortality and reduced offspring production in Aphis gossypii21
Analysis of chloroplast genome characteristics and codon usage bias in 14 species of Annonaceae21
Multihost compatibility of Fusarium oxysporum: early root colonization effectors into the action!20
A curated tissue-specific proteome, phosphoproteome, and kinome map of Drosophila melanogaster with an integrated outlook in circadian physiology20
Integrative single-cell and bulk RNA-seq analysis identifies glycosyltransferases-related signature in triple negative breast cancer20
Using system biology and bioinformatics to identify the influences of COVID-19 co-infection with influenza virus on COPD20
A novel artificial intelligence approach to detect the breast cancer using KNNet technique with EPM gene profiling20
The identification and validation of hub genes associated with advanced IPF by weighted gene co-expression network analysis20
Time-course RNA sequencing reveals high similarity in mRNAome between hepatic stellate cells activated by agalactosyl IgG and TGF-β120
Integrating ex vivo drug sensitivity and genetic mutation analysis improves prediction of chemotherapy response in acute myeloid leukemia19
ASAPA: a bioinformatic pipeline based on Iso-Seq that identifies the links among alternative splicing, alternative transcription initiation and alternative polyadenylation19
Comparative Chloroplast Genomics of Sugar Beet and Wild Relatives: Insights into Photosystem Gene Regulation and Stress Tolerance19
Organ-specific transcriptional and untargeted metabolome analysis demystifies molecular insights and regulation of Gallic acid and flavonoid biosynthesis in Bergenia ciliata19
FAM72A promotes cervical cancer progression by regulating the PI3K pathway19
Transcriptome and WGCNA analyses reveal NtRAP2-7 activates NtACOH1 expression to enhance low potassium tolerance in tobacco19
Retraction Note: Molecular mechanism study and tumor heterogeneity of Chinese angelica and Fructus aurantii in the treatment of colorectal cancer through computational and molecular dynamics19
Benchmarking of bioinformatics tools for NGS-based microRNA profiling with RT-qPCR method18
Single-cell analysis identified PDIA3 as regulator of malignant characteristics and macrophage function in human cancers18
Innovative perspectives on glioblastoma: the emerging role of long non-coding RNAs18
Comparative transcriptome analysis provides insight into the important pathways and key genes related to the pollen abortion in the thermo-sensitive genic male sterile line 373S in Brassica napus L.17
LNCAROD promotes the proliferation and migration of gastric cancer: a bioinformatics analysis and experimental validation17
Host-mediated gene engineering and microbiome-based technology optimization for sustainable agriculture and environment17
Mapping of quantitative trait loci for the nutritional value of fresh market tomato17
Shaping Drosophila eggs: unveiling the roles of Arpc1 and cpb in morphogenesis17
A novel oncogene, leucine-rich repeat protein 1, mediates hypoxia-induced hepatocellular carcinoma progression17
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC17
Integrated analysis of single-cell and bulk RNA sequencing data identifies the characteristics of ferroptosis in lumbar disc herniation17
ETV7 promotes colorectal cancer progression through upregulation of IFIT317
Integrative metabolomic and transcriptomic analysis reveals the genetic basis of terpenoid-mediated aroma diversity in Ocimum species16
Multi-omics based consensus subtypes, development of prognostic signature, and identification of INHBB as a potential therapeutic target in colorectal cancer16
MyeloDB: a multi-omics resource for multiple myeloma16
A novel PADI6 splice-site variant induces non-canonical GC-AG splicing and embryonic arrest in humans16
Reversal of H2O2-induced cell death by knockdown of HOTAIR in HTR-8/SVneo cells by mediation of miR-106b-5p/ACSL4 axis16
Deep transcriptome and metabolome analysis to dissect untapped spatial dynamics of specialized metabolism in Saussurea costus (Falc.) Lipsch16
Tet1-mediated activation of the Ampk signaling by Trpv1 DNA hydroxymethylation exerts neuroprotective effects in a rat model of Parkinson’s disease15
DIA-based proteomic analysis reveals Scutellaria barbata D. Don Exosome-like nanovesicles promote ferroptosis in HCC through Nrf2/SLC7A11/GPX4 pathway15
Architecture and topologies of gene regulatory networks associated with breast cancer, adjacent normal, and normal tissues15
Retraction Note: Integration of clinical and spatial data to explore lipid metabolism-related genes for predicting prognosis and immune microenvironment in gliomas15
Correction to: De novo transcriptome assembly and global analysis of differential gene expression of aphid tolerant wild mustard Rorippa indica (L.) Hiern infested by mustard aphid Lipaphis Erysimi (L15
Genome-wide association studies: an intuitive solution for SNP identification and gene mapping in trees15
Analysis of the regulatory role of miR-34a-5p/PLCD3 in the progression of osteoarthritis15
Comprehensive multi-omics analysis of nucleotide metabolism: elucidating the role and prognostic significance of UCK2 in bladder cancer15
RNA-binding protein BICC1 promotes gastric cancer progression via the PRRX1-MAPK signaling axis15
Epitranscriptomic regulation of diabetic EndMT in HAECs: METTL3-dependent m6A modification promotes endothelial dysfunction15
Retraction Note: Influence of the kappa casein genotype on the technological properties of cow milk of Simmental and Alatau breeds15
UDP-glycosyltransferase gene SlUGT73C1 from Solanum lycopersicum regulates salt and drought tolerance in Arabidopsis thaliana L.14
Genomic and metabolomic characterization of Acinetobacter calcoaceticus (DT1) and Citrobacter braakii (S10) reveal functional traits for plant stress alleviation and sustainable agriculture14
NGS-based profiling identifies miRNAs and pathways dysregulated in cisplatin-resistant esophageal cancer cells14
Retraction Note: Special transcriptome landscape and molecular prognostic signature of non-smoking head and neck cancer patients14
Insights into the functions of MYB29 and MYB28.1 involved in glucosinolate biosynthesis from Isatis indigotica Fort.14
Downregulation of lncRNA CDKN2B-AS1 attenuates inflammatory response in mice with allergic rhinitis by regulating miR-98-5p/SOCS1 axis14
The role of disulfidptosis-associated LncRNA-LINC01137 in Osteosarcoma Biology and its regulatory effects on macrophage polarization14
An integrative analysis of the single-cell transcriptome identifies DUSP4 as an exhaustion-associated gene in tumor-infiltrating CD8+ T cells14
Immunoinformatic prediction of potential immunodominant epitopes from cagW in order to investigate protection against Helicobacter pylori infection based on experimental consequences14
A reproducible endothelial-state contrast with limited bulk prognostic robustness in hepatocellular carcinoma14
Comprehensive analysis of mRNAs in the cerebral cortex in APP/PS1 double-transgenic mice with Alzheimer's disease based on high-throughput sequencing of N4-acetylcytidine14
Transcriptome analysis reveals no obvious unintended effects in the spleen of CRISPR/Cas9-mediated CD163 and pAPN double-knockout pigs13
Circular RNA eukaryotic translation initiation factor 6 facilitates TPC-1 cell proliferation and invasion through the microRNA-138-5p/lipase H axis13
“KRiShI”: a manually curated knowledgebase on rice sheath blight disease13
Transcription factor BrEFM negatively regulates flowering time in Chinese cabbage13
FANCD2 genome binding is nonrandom and is enriched at large transcriptionally active neural genes prone to copy number variation13
Molecular cloning and functional characterization of MhHEC2-like genes in Malus halliana reveals it enhances Fe (iron) deficiency tolerance13
miR-429 inhibits the formation of an immunosuppressive microenvironment to counteract hepatocellular carcinoma immune escape by targeting PD-L113
FOXP3 inhibits inflammatory activation of conjunctival epithelial cells in allergic conjunctivitis via the KAT5/PDCD4 axis13
Effect of gibberellin on crown root development in the mutant of the rice plasmodesmal Germin-like protein OsGER413
Ectopic expression of a grapevine alkaline α-galactosidase seed imbibition protein VvSIP enhanced salinity tolerance in transgenic tobacco plants13
Cancer gene therapy: historical perspectives, current applications, and future directions13
LncRNA TUG1 promotes hepatic lipid accumulation by targeting the miR-29a-3p/SREBP-2/HMGCR axis in MAFLD13
USF1-mediated transcription of PARP1 contributes to sevoflurane-induced pyroptosis in perioperative neurocognitive disorders13
Novel PKP2 compound heterozygous mutations causing neonatal early-onset arrhythmogenic cardiomyopathy: insights into the synergistic pathogenicity of biallelic inactivation13
Polycomb repressive complex 2 (PRC2) pathway’s role in cancer cell plasticity and drug resistance12
Application of quercetin enhances tobacco resistance to Phytophthora nicotianae12
Leptin drives glucose metabolism to promote cardiac protection via OPA1-mediated HDAC5 translocation and Glut4 transcription12
LncRNAs orchestration of gastric cancer - particular emphasis on the etiology, diagnosis, and treatment resistance12
SORL1 stabilizes ABCB1 to promote cisplatin resistance in ovarian cancer12
Kinesin family member 23 knockdown inhibits cell proliferation and epithelial-mesenchymal transition in esophageal carcinoma by inactivating the Wnt/β-catenin pathway12
Identification of genes controlling grain size in barley through RNA-seq and weighted gene co-expression network analysis12
Identification of the Nicotianamine synthase (NAS) gene family in wheat (Triticum aestivum L.) and the role of its member TaNAS4-A in Zn and Fe transport12
Integrated phylogenomic and transcriptomic analyses reveal GhTZP3 as a key gene regulating flowering time and undergoing artificial selection in upland cotton (Gossypium hirsutum)12
Genome-wide identification, characterization, and evolutionary analysis of NBS genes and their association with disease resistance in Musa spp.12
Regulatory mechanism and biological function of UHRF1–DNMT1-mediated DNA methylation12
Protective effect of bone morphogenetic protein-7 induced differentiation of bone marrow mesenchymal stem cells in rat with acute spinal cord injury12
Serine related gene CCT6A promotes metastasis of hepatocellular carcinoma via interacting with RPS312
Single-cell transcriptome analysis identifies novel biomarkers involved in major liver cancer subtypes12
Effect of salinity on ccmfn gene RNA editing of mitochondria in wild barley and uncommon types of RNA editing12
Integrative multi-omics analysis and machine learning identify M2 macrophage–induced ferroptosis resistance in glioblastoma12
Regulatory axis of circular RNA DTNB, microRNA-485-5p, and myeloid cell leukemia 1 attenuates inflammation and apoptosis in caerulein-treated AR42J cells11
Association of MUC3A P258S mutation with advanced phase CML structural and in silico insights11
Integration of clinical and cellular lipidomics identifies a serum metabolite signature predictive of oxaliplatin resistance in colorectal cancer11
A review of ARGOS-mediated regulation of plant organ size: molecular mechanisms, environmental interactions, and agricultural implications11
MYC-SEPT11 Axis Promotes osteoblast differentiation and bone formation via PI3K/AKT and RhoA/ROCK signaling pathways11
Dissecting the genomic landscape of ERD genes in alfalfa (Medicago sativa): the effect of melatonin and low selenium under salt stress11
RETRACTED ARTICLE: RAD54L promotes progression of hepatocellular carcinoma via the homologous recombination repair pathway11
Bronchial epithelial-derived exosomal SLC6A14 promotes airway inflammation and mucus hypersecretion via the ZFP36L1/IL-8 axis11
RETRACTED ARTICLE: Exploring the potential of miR-9a-5p in circadian rhythm and cognitive recovery following brain injury in neonatal rats11
MicroRNA profiling of royal jelly extracellular vesicles and their potential role in cell viability and reversing cell apoptosis11
PSMG3 enhances the proliferation and metastasis of hepatocellular carcinoma via inhibiting HDAC611
Integrative functional genomics maps synaptic and developmental-regulatory autism risk-gene sets across human cortex11
MZB1-Driven Endoplasmic reticulum stress model as a predictor of breast cancer progression and survival11
β-Lapachone sensitizes glioblastoma to Temozolomide by inhibiting NF-κB signaling11
Gene clusters-based pathway enrichment analysis identifies four pan-cancer subtypes with distinct molecular and clinical features11
A new efficient referential genome compression technique for FastQ files11
Honokiol attenuates renal fibrosis via SIRT3-Mediated regulation of Wnt/β-Catenin signaling11
EGF/ERBB2 blocks the endoplasmic reticulum-associated degradation to facilitate chronic obstructive pulmonary disease development by decreasing FAM8A1 via up-regulating DNMT3A11
Integrated analysis of single-cell and bulk RNA sequencing identifies a signature based on macrophage marker genes involved in prostate cancer prognosis and treatment responsiveness11
PFT-α protects the blood-brain barrier through the Wnt/β-catenin pathway after acute ischemic stroke11
Establishment of a prognostic model for melanoma based on necroptosis-related genes11
Comprehensive insights and In silico analysis into the emerging role of LincRNAs in lung diseases pathogenesis; a step toward ncRNA precision11
Autoimmune mechanisms and inflammation in obesity-associated type 2 diabetes, atherosclerosis, and non-alcoholic fatty liver disease11
Comprehensive pan-cancer analysis reveals SIRT5 is a predictive biomarker for prognosis and immunotherapy response11
RETRACTED ARTICLE: Vacuolar protein sorting 35 (VPS35) acts as a tumor promoter via facilitating cell cycle progression in pancreatic ductal adenocarcinoma11
Drought-tolerant wheat for enhancing global food security10
Transcriptome analysis and differential expression in Arabidopsis thaliana in response to rohitukine (a chromone alkaloid) treatment10
Identification of lncRNAs regulating seed traits in Brassica juncea and development of a comprehensive seed omics database10
MHY1485 promotes adriamycin sensitivity in HepG2 cells by inhibiting autophagy10
Prioritization of candidate genes regulating the dwarfness in rice by integration of whole-genome and transcriptome analyses10
Flavonoids: a review on biosynthesis and transportation mechanism in plants10
The mechanism of MMP14-positive tumor-associated fibroblast subsets in inhibiting PD-1 immunotherapy for esophageal cancer through exosomal tsRNA-1052210
Analysis of the complete mitogenome of Daphnia galeata from the Han River, South Korea: structure comparison and control region evolution10
Smeat-seq transcriptomic profiling unveils key regulatory events during Maternal-to-Zygotic transition and supports High-Efficiency culture system development in Tibetan sheep embryos10
NEDD4 facilitates the progression of endometrial carcinoma by enhancing PAMR1 protein degradation through ubiquitination10
Genome-wide association study for boll weight in Gossypium hirsutum races10
LINC02086 inhibits ferroptosis and promotes malignant phenotypes of pancreatic cancer via miR-342-3p/CA9 axis10
Integrative meta-analysis of RNA-Seq data reveals conserved orthologous gene modules and pathways in wheat and rice in response to plant growth-promoting bacteria10
Can nanotechnology and genomics innovations trigger agricultural revolution and sustainable development?10
Correction to: Fantastic genes: where and how to find them? Exploiting rice genetic resources for the improvement of yield, tolerance, and resistance to a wide array of stresses in rice10
GsPKS24, a calcineurin B-like protein-interacting protein kinase gene from Glycine soja, positively regulates tolerance to pH stress and ABA signal transduction10
Weighted gene co-expression network analysis combined with machine learning validation to identify key hub biomarkers in colorectal cancer10
Status and advancement of root-knot nematode management strategies and the emerging CRISPR/Cas biotechnology application10
Potential of underutilized crops to introduce the nutritional diversity and achieve zero hunger10
Circular RNA circ_0022707 impedes the progression of preeclampsia via the miR-3135b/GHR/PI3K/Akt axis9
Trihelix gene identification and functional analysis of HvTH1 regulator’s role in ROS detoxification during salt stress conditions in wild barley9
TRIP 13-dependent pathways promote the development of gastric cancer9
Synergistic inhibition of the PI3K-AKT-mTOR signaling pathway in idiopathic pulmonary fibrosis by Sanleng-Ezhu: a multi-omics and experimental study9
Identification and characterization of TMV-induced volatile signals in Nicotiana benthamiana: evidence for JA/ET defense pathway priming in congeneric neighbors via airborne (E)-2-octenal9
Deciphering the potential molecular network underlying nicotine- and its metabolite cotinine-induced myocardial infarction via network toxicology, molecular dynamics, and in vitro experimental validat9
Exploring the m5C epitranscriptome of mRNAs in breast cancer cells through genome engineering and long-read sequencing approaches9
Immune-related biomarkers predict the prognosis and immune response of breast cancer based on bioinformatic analysis and machine learning9
Comparative transcriptomics unravels new genes imparting scab resistance in apple (Malus x domestica Borkh.)9
Integrative analysis identifies FERMT3 as a key regulator of metabolic reprogramming in keloid scarring and metabolic syndrome9
LncRNA FOXP4-AS1 promotes glioma cell proliferation, metastasis, and glycolysis via the miR-136-5p/ADCYAP1R1 axis9
CRISPR-Cas9-mediated deletion enhancer of MECOM play a tumor suppressor role in ovarian cancer9
CXCL2 is associated with IL-6/JAK2/STAT3 signaling and the immune microenvironment in lung squamous cell carcinoma9
SOCS2 regulation myoblast differentiation of Hu sheep via STAT3/PSMB9 pathway9
The impact of CsPSKs on plant immunity: insights from a genome-wide study of small peptides in Citrus sinensis9
Characterization of 4-coumarate CoA ligase (4CL) gene family and functional study of Sm4CL2/3/7/9 in Salvia miltiorrhiza9
Liensinine ameliorates ischemia–reperfusion-induced brain injury by inhibiting autophagy via PI3K/AKT signaling9
Identification of two variants in PAX3 and FBN1 in a Chinese family with Waardenburg and Marfan syndrome via whole exome sequencing9
STEAP3 regulates ferroptosis through mitochondrial metabolic dysfunction to impact the malignant proliferation of ovarian cancer cells9
Multi-omics integration reveals YWHAE as a key mediator of ferroptosis in ARDS9
Epidemiology, pathogenesis, immune evasion mechanism and vaccine development of porcine Deltacoronavirus9
A novel mitochondria-related gene signature in esophageal carcinoma: prognostic, immune, and therapeutic features9
Genetic regulation of major immunogenic protein accumulation in peanut seeds9
Gene-sized editing for the therapy of genetic diseases9
SIGMAR1 targets AMPK/ULK1 pathway to inhibit SH-SY5Y cell apoptosis by regulating endoplasmic reticulum stress and autophagy9
Comparative genomics and integrated system biology approach unveiled undirected phylogeny patterns, mutational hotspots, functional patterns, and molecule repurposing for monkeypox virus9
Ubiquitination-specific protease 7 enhances stemness of hepatocellular carcinoma by stabilizing basic transcription factor 38
LRRC8A/PKC/FLNA pathway activation is detrimental to colon cancer patients8
The pan-genome of the emerging multidrug-resistant pathogen Corynebacterium striatum8
Unscheduled excessive R-loops in immune response8
LncRNAs in hypoxic microenvironment; insight in their impact in cancer biology8
Identification of the PLATZ gene family in Cucurbita pepo and functional analysis of CpPLATZ4 in powdery mildew stress response8
Synonymous sites for accessibility around microRNA binding sites in bacterial spot and speck disease resistance genes of tomato8
Correction to: Genome‑wide association studies: an intuitive solution for SNP identification and gene mapping in trees8
Identification, characterization, and comprehensive expression profiling of floral master regulators in pigeon pea (Cajanus cajan [L.] Millspaugh)8
Genome-wide analysis of the SWEET gene family in quinoa and functional study of CqSWEET14 in drought resistance8
Correction to: Single‑cell analysis identified PDIA3 as regulator of malignant characteristics and macrophage function in human cancers8
Joint multi-omics analysis reveals the response mechanism in rapeseed (Brassica Rapa L.) under low nitrogen stress8
Epigenetic gene silencing in plants: Insights from triplet repeat expansion in Arabidopsis8
Correction to: MicroRNAs regulating Wnt signaling pathway in colorectal cancer: biological implications and clinical potentials8
A single-cell cell-of-origin audit of the lncRNA RMST: bulk expression under-represents its broad neural expression and over-attributes a liver biomarker8
Single-cell and spatial transcriptomics identify CAPG as a key driver of cisplatin resistance in bladder cancer8
CircSHPRH inhibits malignancy progression of head and neck squamous cell carcinoma by regulating PI3K/AKT/mTOR signaling pathway8
Genome-wide identification of TCP gene family and gene editing of BjTCP18 genes increases branching in Brassica juncea8
YTHDF1–ALYREF axis enhances mrna stability and tumor immune evasion in paediatric B-cell acute lymphoblastic leukemia8
Antler-derived microRNA PC-5p-1090 inhibits HCC cell proliferation, migration, and invasion by targeting MARCKS, SMARCAD1, and SOX98
Correction to: Flavonoids: a review on biosynthesis and transportation mechanism in plants8
Dihydrolipoamide dehydrogenase promotes hepatocellular carcinoma progression and modulates cuproptosis-dependent cell death8
Identification of exosomes-related lncRNAs in clear cell renal cell carcinoma based on Bayesian spike-and-slab lasso approach8
Candidate genes for anthracnose resistance in Senegalese sorghum: a machine learning-based exploration8
Deltex E3 ubiquitin ligase 4 promotes thyroid cancer progression through stearoyl-CoA desaturase 18
Genome-wide characterization and comparative analysis of Bacillus paranthracis MBBL1 reveals genomic plasticity features8
Knockout of SSIIa in waxy barley blocks starch biosynthesis and increases soluble sugar and Fructan accumulation8
Complete chloroplast genome of the Malus baccata var. gracilis provides insights into the evolution and phylogeny of Malus species8
Comprehensive profiling of Bcl-2-associated athanogene (BAG) genes and their genetic potential role under cold stress in Cotton8
De novo transcriptome sequencing of drought tolerance–associated genes in little millet (Panicum sumatrense L.)8
Harnessing natural compounds to modulate miRNAs in breast cancer therapy8
Integration of metabolite and transcriptome profiles of cultivated and wild rice to unveil gene regulatory networks and key genes determining rice source and sink strength8
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