Clinical Chemistry and Laboratory Medicine

Article	Citations
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of zonisamide in human serum and plasma	72
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of primidone in human serum and plasma	69
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of gabapentin in human serum and plasma	67
Interest of minigene splicing reporter assay in familial hypobetalipoproteinemia genetic diagnosis: the example of the missense mutation APOB c.1468C>T	62
Urinary exosomal CD26 is associated with recovery from acute kidney injury in intensive care units: a prospective cohort study	61
Comparison of the QuikRead go® point-of-care faecal immunochemical test for haemoglobin with the FOB Gold Wide® laboratory analyser to diagnose colorectal cancer in symptomatic p	60
43rd annual conference of the association of clinical biochemists in Ireland (ACBI 2021)	56
Evaluation of AUTION EYE AI-4510 flow cell morphology analyzer for counting particles in urine	49
Interest of hair tests to discriminate a tail end of a doping regimen from a possible unpredictable source of a prohibited substance in case of challenging an anti-doping rule violation	46
Identifying predictors of varices grading in patients with cirrhosis using ensemble learning	46
Effects of different pepsinogen cut offs in the screening of apparently healthy people	45
Confounding factors of the expression of mTBI biomarkers, S100B, GFAP and UCH-L1 in an aging population	44
S100B vs. “GFAP and UCH-L1” assays in the management of mTBI patients	42
Personalised Medicine, including pharmacogenetics	40
COVID-19	40
Effect of preexamination conditions in a centralized-testing model of non-invasive prenatal screening	40
EFLM Symposium - Quality in clinical laboratory: a moving target	39
Laboratory Management	39
Digital health, big data and smart technologies	38
Symposium 5 - Autoimmune Diseases	35
EFLM Symposium - Precision Medicine	35
Green laboratories	34
Miscellaneous	34
Cardiovascular diseases and cardiac biomarkers	33
Inflammation, vascular biology, endothelium, and oxidative stress	31

IFCC Symposium - Artificial intelligence applications in clinical laboratory medicine	30
Symposium 7 - Young Scientist Session	30
Educational Workshops Abstracts	29
Clinical cases – Preanalytical mysteries	29
Plenary 4 - Diagnostic advances in dementia	29
Two co-inherited hemoglobin variants revealed by capillary electrophoresis during quantification of glycated hemoglobin	28
Presence of SARS-CoV-2 RNA in COVID-19 survivors with post-COVID symptoms: a systematic review of the literature	27
Biomarkers in cancer	26
Adherence to recommendations and clinical practice guidelines: not an easy task	26
Frontmatter	26
The MBL2 genotype relates to COVID-19 severity and may help to select the optimal therapy	26
Analytical interference of intravascular contrast agents with clinical laboratory tests: a joint guideline by the ESUR Contrast Media Safety Committee and the Preanalytical Phase Working Group of the	26
How to evaluate fixed clinical QC limits vs. risk-based SQC strategies	26
Quantitative profiling of inflammatory and pro-resolving lipid mediators in human adolescents and mouse plasma using UHPLC-MS/MS	26
CSF-interleukin 6 for early diagnosis of ventriculitis in a broad intensive care setting	25
Stability of lactate in venous blood gas and sodium fluoride-potassium oxalate plasma: a 6-year retrospective database analysis	25
Lumipulse G SARS-CoV-2 Ag assay evaluation using clinical samples from different testing groups	25
Pancreatic lipase: why laboratory community does not take enough care of this clinically important test?	23
In reply to: Limitations in using the EFLM WG-A/ISO approach for assessment of reagent lot variability	22
Quantification of blood glial fibrillary acidic protein using a second-generation microfluidic assay. Validation and comparative analysis with two established assays	22
The underestimated potential of vibrational spectroscopy in clinical laboratory medicine: a translational gap to close	21
Direct-to-consumer testing – benefits for consumers, people with disease and public health	21
Harmonization status of procalcitonin measurements: what do comparison studies and EQA schemes tell us?	21
Preanalytical quality improvement – an interdisciplinary journey	21
Anti-Ki/anti-PA28γ autoantibodies contribute to the HEp-2 indirect immunofluorescence nuclear speckled pattern	20
A simulation model for organization and management skills assessment that meets ISO 15189	20
Evaluation of ichroma™ COVID-19 interferon gamma release assay for detection of vaccine-induced immunity in healthcare workers	20
Toxicology, including therapeutic drug monitoring	20
Notification of biochemistry critical results and its clinical impact on outpatient care: experience in a Spanish tertiary hospital	19
Circulating pro-gastrin releasing peptide (ProGRP) in patients with medullary thyroid carcinoma	19
Validation of ELISA assays for the calculation of FLC indices for the diagnosis of intrathecal immunoglobulin synthesis	19
Statistics in diagnostic medicine	19
A novel LC-MS/MS-based assay for the simultaneous quantification of aldosterone-related steroids in human urine	18
Discriminating signal from noise: the biological variation of circulating calprotectin in serum and plasma	18
Clinical specificity of two assays for immunoglobulin kappa and lambda free light chains	18
What could cause a false increase in serum C-reactive protein concentration?	18
Measurement uncertainty estimation of free drug concentrations in clinical laboratories using equilibrium dialysis	18
Web-accessible critical limits and critical values for urgent clinician notification	17
Insight into the status of plasma renin and aldosterone measurement: findings from 526 clinical laboratories in China	17
Frontmatter	17
The influence of undetected hemolysis on POCT potassium results in the emergency department	17
Diagnostic performance of a point of care high-sensitivity cardiac troponin I assay and single measurement evaluation to rule out and rule in acute coronary syndrome	17
Standardisation and harmonisation of thyroid-stimulating hormone measurements: historical, current, and future perspectives	17
Reference intervals of 24 trace elements in blood, plasma and erythrocytes for the Slovenian adult population	17
Absolute quantitation of human serum cystatin C: candidate reference method by 15N-labeled recombinant protein isotope dilution UPLC-MS/MS	16
Ligand binding assay-related underestimation of 25-hydroxyvitamin D in pregnant women exaggerates the prevalence of vitamin D insufficiency	16
Neonatal lymphocyte subpopulations analysis and maternal preterm premature rupture of membranes: a pilot study	16
Reply to Abildgaard et al.: lot variation and inter-device differences contribute to poor analytical performance of the DCA vantage™ HbA1cPOCT instrument in a true clinical setting	16
Patients with severe COVID-19 do not have elevated autoantibodies against common diagnostic autoantigens	16
Circulating tumor DNA measurement: a new pillar of medical oncology?	16

Hypertriglyceridemia, a causal risk factor for atherosclerosis, and its laboratory assessment	16
The impact of physiological variations on personalized reference intervals and decision limits: an in-depth analysis	16
Repository of intra- and inter-run variations of quantitative autoantibody assays: a European multicenter study	16
TSH-receptor autoantibodies in patients with chronic thyroiditis and hypothyroidism	16
Multicenter study to compare the diagnostic performance of CLIA vs. FEIA transglutaminase IgA assays for the diagnosis of celiac disease	16
Frontmatter	15
Prospective serological evaluation of anti SARS-CoV-2 IgG and anti S1-RBD antibodies in a community outbreak	15
The clinical significance of the peritoneal dialysis evaluation test in the Department of Laboratory Medicine	15
60th National Congress of the Hungarian Society of Laboratory Medicine	15
Covert poisoning with difenacoum: diagnosis and follow-up difficulties	15
Corrigendum to: Age appropriate reference intervals for eight kidney function and injury markers in infants, children and adolescents	15
Prognostic significance of smudge cell percentage in chronic lymphocytic leukemia. Facts or artifacts? Methodological considerations and literature review	15
Presepsin levels in neonatal cord blood are not influenced by maternal SARS-CoV-2 infection	15
Frontmatter	15
4th National Point of Care Testing Symposium	15
Caveat emptor – hidden pitfalls in defining the 99th percentile of cardiac troponin assays	15
9th Annual Meeting of the Austrian Society for Laboratory Medicine and Clinical Chemistry (ÖGLMKC)	15
Non-esterified fatty acids (NEFA): sample stability and effect of haemolysis and icterus	14
Monocyte distribution width (MDW) as a reliable biomarker for urosepsis	14
Frontmatter	14
Frozen serum sample pool should not be used as internal quality assessment for lipemia (L) index	14
C-reactive protein interacts with amphotericin B liposomes and its potential clinical consequences	14
About the estimation of albuminuria based on proteinuria results	14
Recent advances in laboratory hematology reflected by a decade of CCLM publications	14
The European Register of Specialists in Clinical Chemistry and Laboratory Medicine: code of conduct, version 3 – 2023	14
Stability of SARS-CoV-2 respiratory samples in non-freezing condition: importance for tropical countries under heavy diagnostic demand	14
Quantitation of cardiac troponin I in cancer patients treated with immune checkpoint inhibitors: a case-control study	14
Seroprevalence of SARS-CoV-2 antibodies in Italy in newborn dried blood spots	14
A comprehensive survey of artificial intelligence adoption in European laboratory medicine: current utilization and prospects	13
Reply to: “Is uracil enough for effective pre-emptive DPD testing?”	13
Limitations in using the EFLM WG-A/ISO approach for assessment of reagent lot variability	13
Results of a SARS-CoV-2 virus genome detection external quality assessment round focusing on sensitivity of assays and pooling of samples	13
A vision to the future: value-based laboratory medicine	13
The correlation of albumin with total protein concentrations in cerebrospinal fluid across three automated analysers – relevance to the diagnosis of subarachnoid haemorrhage in clinical chemistry prac	13
Higher troponin T serum concentrations in hospital patients without diagnosed cardiac diseases compared to a population-based cohort	13
Quantitative serological evaluation as a valuable tool in the COVID-19 vaccination campaign	13
Analytical validation of the amplification refractory mutation system polymerase chain reaction-capillary electrophoresis assay to diagnose spinal muscular atrophy	13
A new method for early cancer detection based on platelet transcriptomics will have low positive predictive value	13
Patient result monitoring of HbA1c shows small seasonal variations and steady decrease over more than 10 years	13
Performance of the 2009 CKDEPI, 2021 CKDEPI, and EKFC equations among high-risk patients in Denmark	13
Coagulation parameters in the newborn and infant – the Copenhagen Baby Heart and COMPARE studies	13
Interpretable machine learning model to detect chemically adulterated urine samples analyzed by high resolution mass spectrometry	12
Impact of storage temperature and time before analysis on electrolytes (Na+, K+, Ca2+), lactate, glucose, blood gases (pH, pO2, pCO2), tHb, O	12
Reply to: Spurious results for total and free prostate-specific antigen (PSA); sometimes really “a riddle wrapped in a mystery inside an enigma”	12
Indirectly determined reference intervals for automated white blood cell differentials of pediatric patients in Berlin and Brandenburg	12
The chitinases as biomarkers in immune-mediate diseases	12
Blood sampling frequency as a proxy for comorbidity indices when identifying patient samples for review of reference intervals	12
Pre-analytical considerations for the analysis of uracil and 5,6-dihydrouracil in heparin plasma	12
Targeted quantitative lipidomic uncovers lipid biomarkers for predicting the presence of compensated cirrhosis and discriminating decompensated cirrhosis from compensated cirrhosis	12
Total Testing Process, including standardisation, preanalytical process	12
Misdiagnosis of Hb Bart’s disease: prenatal screening and diagnosis of thalassemia in special population	12
Within- and between-subject biological variation data for serum zinc, copper and selenium obtained from 68 apparently healthy Turkish subjects	12
Diagnostic performance of machine learning models using cell population data for the detection of sepsis: a comparative study	12
Acetylcholine receptor and muscle-specific tyrosine kinase antibodies detection: is it time for a change?	12
Navigating between perpendicular drop and tangent skimming methods for M-protein quantification: a call for clarification of guidelines	12
Analytical evaluation of a GAD65 antibodies chemiluminescence immunoassay for CSF in neurological syndromes	12
Comparison of four indirect (data mining) approaches to derive within-subject biological variation	12
Serum hepcidin levels in chronic liver disease: a systematic review and meta-analysis	11
Effects of lipemia on capillary serum protein electrophoresis in native ultra-lipemic material and intravenous lipid emulsion added sera	11
Design of an algorithm for the detection of intravenous fluid contamination in clinical laboratory samples	11
Machine learning-based nonlinear regression-adjusted real-time quality control modeling: a multi-center study	11
Within-subject biological variation estimates using an indirect data mining strategy. Spanish multicenter pilot study (BiVaBiDa)	11
Development of a liquid chromatography mass spectrometry method for the determination of vitamin K1, menaquinone-4, menaquinone-7 and vitamin K1-2,3 epoxide in serum of individuals without vitamin K s	11
External quality assessment providers’ services appear to more impact the immunohaematology performance of laboratories than national regulatory and economic conditions	11
The importance of correct stratifications when comparing directly and indirectly estimated reference intervals	11
Common laboratory tests as indicators of COVID-19 severity on admission at high altitude: a single-center retrospective study in Quito (ECUADOR)	11
Improving diagnosis and treatment of hypomagnesemia	11
Long-term stability of 25-hydroxyvitamin D: importance of the analytical method and of the patient matrix	11
Serial measurement of circulating calprotectin as a prognostic biomarker in COVID-19 patients in intensive care setting	11
Letter to the Editor regarding the article by Wayne J. Dimech et al. Time to address quality control processes applied to antibody testing for infectious diseases. Clin Chem Lab Med 2023; 61(2):205–21	11
Relationships between renal function variations and relative changes in cardiac troponin T concentrations based on quantile generalized additive models (qgam)	11
Monocyte distribution width as an early predictor of short-term outcome in adult patients with sepsis	11
Diagnostic performance of the fully automated Roche Elecsys SARS-CoV-2 antigen electrochemiluminescence immunoassay: a pooled analysis	11
APS calculator: a data-driven tool for setting outcome-based analytical performance specifications for measurement uncertainty using specific clinical requirements and population data	10
25-Hydroxyvitamin D concentrations in COVID-19 patients hospitalized in intensive care unit during the first wave and the second wave of the pandemic	10
The correlation of urea and creatinine concentrations in sweat and saliva with plasma during hemodialysis: an observational cohort study	10
Implementation and challenges of portable blood gas measurements in air medical transport	10
Rapid rule-in and rule-out protocols of acute myocardial infarction using hs-cTnI and hs-cTnT methods	10
Bland and Altman agreement method: to plot differences against means or differences against standard? An endless tale?	10
Development of a candidate reference measurement procedure by ID-LC-MS/MS for total tau protein measurement in cerebrospinal fluid (CSF)	10

Anti-phosphatidyl-serine/prothrombin antibodies (aPS/PT) in isolated lupus anticoagulant (LA): is their presence linked to dual test positivity?	10
Monocyte distribution width (MDW): study of reference values in blood donors	10
Case report	10
Laboratory medicine in the COVID-19 era: six lessons for the future	10
Evaluation of the analytical and clinical performance of a new high-sensitivity cardiac troponin I assay: hs-cTnI (CLIA) assay	10
Chatbot GPT can be grossly inaccurate	10
Crioplast® is a reliable device to ensure pre-analytical stability of adrenocorticotrophin (ACTH)	10
Machine learning-based clinical decision support using laboratory data	10
Health Technology Assessment to assess value of biomarkers in the decision-making process	10
Clinical lipidomics in the era of the big data	9
Amino acid sequence homology of monoclonal serum free light chain dimers and tissue deposited light chains in AL amyloidosis: a pilot study	9
Analysis of cryoproteins with a focus on cryofibrinogen: a study on 103 patients	9
Deciphering the role of monocyte and monocyte distribution width (MDW) in COVID-19: an updated systematic review and meta-analysis	9
Allergy: Evaluation of 16 years (2007–2022) results of the shared external quality assessment program in Belgium, Finland, Portugal and The Netherlands	9
Reference ranges for GDF-15, and risk factors associated with GDF-15, in a large general population cohort	9
Low free-T3 serum levels and prognosis of COVID-19: systematic review and meta-analysis	9
Pediatric reference interval verification for endocrine and fertility hormone assays on the Abbott Alinity system	9
Assessment of humoral and cellular immunity after bivalent BNT162b2 vaccination and potential association with reactogenicity	9
A promising new direct immunoassay for urinary free cortisol determination	9
External quality assessment for detection of methylated Syndecan 2 (SDC2) in China	9
Cell population data: much more to explore	9
How to best use procalcitonin to diagnose infections and manage antibiotic treatment	9
Effect of BNT162b2 booster dose on anti-SARS-CoV-2 spike trimeric IgG antibodies in seronegative individuals	9
Biological variation estimates obtained from Chinese subjects for 32 biochemical measurands in serum	9
Increased specificity of the “GFAP/UCH-L1” mTBI rule-out test by age dependent cut-offs	9
Aggregated data from the same laboratories participating in two glucose external quality assessment schemes show that commutability and transfers of values to control materials are decisive for the bi	9
Concomitant immune thrombocytopenia and bone marrow hemophagocytosis in a patient with SARS-CoV-2	9
Overcoming challenges regarding reference materials and regulations that influence global standardization of medical laboratory testing results	9
Disruption vs. evolution in laboratory medicine. Current challenges and possible strategies, making laboratories and the laboratory specialist profession fit for the future	9
Diagnostic utility of pleural cell-free nucleic acids in undiagnosed pleural effusions	9
Three rounds of a national external quality assessment reveal a link between disharmonic anti-SARS-CoV-2 antibody quantifications and the infection stage	9
Integration of artificial intelligence and plasma steroidomics with laboratory information management systems: application to primary aldosteronism	9
The EU Green Deal: the challenge of greening medical technologies	9
Drone transport of biological samples: an open issue	9
Evaluation of analytical performance of homocysteine LC-MS/MS assay and design of internal quality control strategy	9
A novel scoring system combining Modified Early Warning Score with biomarkers of monocyte distribution width, white blood cell counts, and neutrophil-to-lymphocyte ratio to improve early sepsis predic	9
Machine learning to optimize cerebrospinal fluid dilution for analysis of MRZH reaction	9
Complexity of serological assays and misunderstandings of WHO International Units	9
Proenkephalin A 119–159 (penKid) – a novel biomarker and its quantification on the Nexus IB10 POC system for assessing kidney function	9
Accurate non-ceruloplasmin bound copper: a new biomarker for the assessment and monitoring of Wilson disease patients using HPLC coupled to ICP-MS/MS	9
Multiplex proteomics using proximity extension assay for the identification of protein biomarkers predictive of acute graft-vs.-host disease in allogeneic hematopoietic cell transplantation	9
Analysis of a second-tier test panel in dried blood spot samples using liquid chromatography-tandem mass spectrometry in Catalonia’s newborn screening programme	9
Detection of DNA copy number alterations by matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of single nucleotide polymorphisms	9
Description and validation of an equilibrium dialysis ID-LC-MS/MS candidate reference measurement procedure for free thyroxine in human serum	8
Turnaround time prediction for clinical chemistry samples using machine learning	8
Labile glycated hemoglobin: an underestimated laboratory marker of short term glycemia	8
Blood lactate concentration in COVID-19: a systematic literature review	8
Clostebol and sport: about controversies involving contamination vs. doping offence	8
Plasmacytoid dendritic cell proliferation and acute myeloid leukemia with minimal differentiation (AML-M0)	8
Biological variation estimates of thyroid related measurands – meta-analysis of BIVAC compliant studies	8
Moving average quality control of routine chemistry and hematology parameters – a toolbox for implementation	8
Simple flow cytometry method using a myeloma panel that easily reveals clonal proliferation of mature B-cells	8
Reference intervals of 14 biochemical markers for children and adolescence in China: the PRINCE study	8
Effects of storage conditions on the stability of blood-based markers for the diagnosis of Alzheimer’s disease	8
Recommendation for the design of stability studies on clinical specimens	8
Neutralizing antibody titers six months after Comirnaty vaccination: kinetics and comparison with SARS-CoV-2 immunoassays	8
Analytical and clinical evaluations of SNIBE Maglumi chemiluminescent immunoassay for the detection of SARS-CoV-2 antigen in salivary samples	8
Incidence, characteristics and outcomes among inpatient, outpatient and emergency department with reported high critical serum potassium values	8
Analytical performance specifications for trace elements in biological fluids derived from six countries federated external quality assessment schemes over 10 years	8
Evaluating the accuracy of ChatGPT in classifying normal and abnormal blood cell morphology	8
Behind the scenes of EQA – characteristics, capabilities, benefits and assets of external quality assessment (EQA)	8
Diagnostic performances and cut-off verification of blood pTau 217 on the Lumipulse platform for amyloid deposition in Alzheimer’s disease	8
EN ISO 15189 revision: EFLM Committee Accreditation and ISO/CEN standards (C: A/ISO) analysis and general remarks on the changes	8
Individual risk prediction of high grade prostate cancer based on the combination between total prostate-specific antigen (PSA) and free to total PSA ratio	8
Isotope dilution LC-MS/MS quantification of the cystic fibrosis transmembrane conductance regulator (CFTR) modulators ivacaftor, lumacaftor, tezacaftor, elexacaftor, and their major metabolites in hum	8
Monocyte distribution width (MDW) as a screening tool for early detecting sepsis: a systematic review and meta-analysis	8
Prognostic value of anti-SARS-CoV-2 antibodies: a systematic review	8
Theranos revisited: the trial and lessons learned	8
Behind the scenes of EQA–characteristics, capabilities, benefits and assets of external quality assessment (EQA)	8
Analytical verification of the Atellica VTLi point of care high sensitivity troponin I assay	8
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of aldosterone in human serum and plasma	8
Assessing vitamin D metabolism – four decades of experience	8
The stability of C-peptide and insulin in plasma and serum samples under different storage conditions	8
Direct-to-consumer testing as consumer initiated testing: compromises to the testing process and opportunities for quality improvement	8
External quality assessment-based tumor marker harmonization simulation; insights in achievable harmonization for CA 15-3 and CEA	8
Frontmatter	7
Disturbances of calcium, magnesium, and phosphate homeostasis: incidence, probable causes, and outcome	7
Dynamic mirroring: unveiling the role of digital twins, artificial intelligence and synthetic data for personalized medicine in laboratory medicine	7
OILVEQ: an Italian external quality control scheme for cannabinoids analysis in galenic preparations of cannabis oil	7
Clinical applications of circulating tumor cell detection: challenges and strategies	7
A comparative analysis of current С-peptide assays compared to a reference method: can we overcome inertia to standardization?	7
Diagnostic value of procalcitonin, hypersensitive C-reactive protein and neutrophil-to-lymphocyte ratio for bloodstream infections in pediatric tumor patients	7
External quality assurance (EQA): navigating between quality and sustainability	7
Validation of the enhanced liver fibrosis (ELF)-test in heparinized and EDTA plasma for use in reflex testing algorithms for metabolic dysfunction-associated steatotic liver disease (MASLD)	7
Frontmatter	7
The final part of the CRESS trilogy – how to evaluate the quality of stability studies	7
Knowledge among clinical personnel on the impact of hemolysis using blood gas analyzers	7
Biomarkers in the management of lung cancer: changing the practice of thoracic oncology	7
Soluble CD40 ligand and outcome in patients with coronary artery disease undergoing percutaneous coronary intervention	7
Mass spectrometry in the clinical laboratory. A short journey through the contribution to the scientific literature by CCLM	7
Use of the term “Bence-Jones proteinuria” in the EFLM European Urinalysis Guideline 2023	7
QC Constellation: a cutting-edge solution for risk and patient-based quality control in clinical laboratories	7
EFLM Task Force Preparation of Labs for Emergencies (TF-PLE) recommendations for reinforcing cyber-security and managing cyber-attacks in medical laboratories	7
Recommendations for IVDR compliant in-house software development in clinical practice: a how-to paper with three use cases	7
Point-of-care testing, near-patient testing and patient self-testing: warning points	7