Clinical Chemistry and Laboratory Medicine

Article	Citations
Machine learning-based delta check method for detecting misidentification errors in tumor marker tests	87
Performance of the 2009 CKDEPI, 2021 CKDEPI, and EKFC equations among high-risk patients in Denmark	79
Acetylcholine receptor and muscle-specific tyrosine kinase antibodies detection: is it time for a change?	75
Coagulation parameters in the newborn and infant – the Copenhagen Baby Heart and COMPARE studies	73
Discriminating signal from noise: the biological variation of circulating calprotectin in serum and plasma	66
Measurement uncertainty estimation of free drug concentrations in clinical laboratories using equilibrium dialysis	57
Plenary 4 - Diagnostic advances in dementia	56
Analytical interference of intravascular contrast agents with clinical laboratory tests: a joint guideline by the ESUR Contrast Media Safety Committee and the Preanalytical Phase Working Group of the	51
Serial measurement of circulating calprotectin as a prognostic biomarker in COVID-19 patients in intensive care setting	50
A novel LC-MS/MS-based assay for the simultaneous quantification of aldosterone-related steroids in human urine	47
COVID-19	41
Design of an algorithm for the detection of intravenous fluid contamination in clinical laboratory samples	41
Insight into the status of plasma renin and aldosterone measurement: findings from 526 clinical laboratories in China	40
Multiplex proteomics using proximity extension assay for the identification of protein biomarkers predictive of acute graft-vs.-host disease in allogeneic hematopoietic cell transplantation	39
Diagnostic performance of machine learning models using cell population data for the detection of sepsis: a comparative study	38
Analytical performance specifications for trace elements in biological fluids derived from six countries federated external quality assessment schemes over 10 years	38
Behind the scenes of EQA – characteristics, capabilities, benefits and assets of external quality assessment (EQA)	35
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of aldosterone in human serum and plasma	35
Results of a SARS-CoV-2 virus genome detection external quality assessment round focusing on sensitivity of assays and pooling of samples	35
Diagnostic performance of a point of care high-sensitivity cardiac troponin I assay and single measurement evaluation to rule out and rule in acute coronary syndrome	35
Quantification of blood glial fibrillary acidic protein using a second-generation microfluidic assay. Validation and comparative analysis with two established assays	34
Web-accessible critical limits and critical values for urgent clinician notification	33
Development of a liquid chromatography mass spectrometry method for the determination of vitamin K1, menaquinone-4, menaquinone-7 and vitamin K1-2,3 epoxide in serum of individuals without vitamin K s	33
Preanalytical quality improvement – an interdisciplinary journey	33
Presence of SARS-CoV-2 RNA in COVID-19 survivors with post-COVID symptoms: a systematic review of the literature	31

Monocyte distribution width (MDW) as a screening tool for early detecting sepsis: a systematic review and meta-analysis	31
Cell population data: much more to explore	31
Overcoming challenges regarding reference materials and regulations that influence global standardization of medical laboratory testing results	31
Evaluation of the analytical and clinical performance of a new high-sensitivity cardiac troponin I assay: hs-cTnI (CLIA) assay	30
EN ISO 15189 revision: EFLM Committee Accreditation and ISO/CEN standards (C: A/ISO) analysis and general remarks on the changes	30
Moving average quality control of routine chemistry and hematology parameters – a toolbox for implementation	30
Quantitative profiling of inflammatory and pro-resolving lipid mediators in human adolescents and mouse plasma using UHPLC-MS/MS	29
Not all biases are created equal: how to deal with bias on laboratory measurements	27
Frontmatter	27
Multicenter study to compare the diagnostic performance of CLIA vs. FEIA transglutaminase IgA assays for the diagnosis of celiac disease	27
Statistics in diagnostic medicine	26
NT-proBNP use in old patients and the impact of the selected threshold value: a big data analysis	26
Emerging technology: a definition for laboratory medicine	25
Quality in laboratory medicine and the Journal: walking together	25
Frontmatter	25
Evaluation of biochemical algorithms to screen dysbetalipoproteinemia in ε2ε2 and rare APOE variants carriers	25
One fits all: a highly sensitive combined ddPCR/pyrosequencing system for the quantification of microchimerism after hematopoietic and solid organ transplantation	25
Microbiology - Infectious diseases including COVID 19	24
Epigenetic signatures of cfDNA enable a topological assignment of tissue damage	23
Reference intervals and decision limits	23
The impact of COVID-19 on citations of laboratory medicine journals	23
Frontmatter	23
Stability of plasma renin concentration based on plasma freezing time, as an adjunct to the stability data reported in the paper by Hepburn and others	22
Precision Medicine	22
The 10+1 Santorini Conference	22
ISMD2024 Thirteenth International Symposium on Molecular Diagnostics	22
Kidney diseases and transplantation, urinanalysis	22
IgG and kappa free light chain CSF/serum indices: evaluating intrathecal immunoglobulin production in HIV infection in comparison with multiple sclerosis	21
53rd National Congress of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC – Laboratory Medicine)	21
Laboratory response to paradigm change in hemophilia treatment	21
Biological matrices, reagents and turnaround-time: the full-circle of artificial intelligence in the pre-analytical Phase. Comment on Turcic A, et al., Machine learning to optimize cerebrospinal fluid	21
Clinical Studies - Outcomes	21
Analytical performance specifications – moving from models to practical recommendations	20
Pseudo-erythroblastosis on Sysmex XN hematology analyzers: a clue to Candida sepsis. Case report and literature review	20
Comparison of near-infrared and UV–vis-based non-contact hematocrit prediction of dried blood spots from patients on immunosuppressants	20
Cell population data for early detection of sepsis in patients with suspected infection in the emergency department	20
Evaluation of effects from hemoglobin variants on HbA1c measurements by different methods	20
Concordance between the updated Elecsys cerebrospinal fluid immunoassays and amyloid positron emission tomography for Alzheimer’s disease assessment: findings from the Apollo study	20
Neonatal reference intervals for serum steroid hormone concentrations measured by LC-MS/MS	20
Analytical evaluation of the novel Mindray high sensitivity cardiac troponin I immunoassay on CL-1200i	19
Drainage fluid LDH and neutrophil to lymphocyte ratio as biomarkers for early detecting anastomotic leakage in patients undergoing colorectal surgery	19
Dynamics of the vitamin D C3-epimer levels in preterm infants	19
Response to Tony Badrick regarding “Letter to the Editor regarding the article by Wayne J. Dimech et al. Time to address quality control processes applied to antibody testing for infectious diseases.	19
Greater expectations: meeting clinical needs through broad and rapid genomic testing	19
Biological variation of serum cholinesterase activity in healthy subjects	19
Long-term effects of interventions applied to optimize the use of 25-OH vitamin D tests in primary health care	18
International collaborative study to evaluate and calibrate two recombinant L chain Ferritin preparations for use as a WHO International Standard	18
Colorimetric correcting for sample concentration in stool samples	18
Serum sPD-L1 levels are elevated in patients with viral diseases, bacterial sepsis or in patients with impaired renal function compared to healthy blood donors	18
Familial dysalbuminemic hyperthyroxinemia coexisting with a Grave’s disease: a Belgian case report	18

Frontmatter	18
Use of the term “Bence-Jones proteinuria” in the EFLM European Urinalysis Guideline 2023	17
Benchmarking medical laboratory performance: survey validation and results for Europe, Middle East, and Africa	17
An improved implementation of metrological traceability concepts is needed to benefit from standardization of laboratory results	17
Clinical utility of personalized reference intervals for CEA in the early detection of oncologic disease	17
IgA rheumatoid factor in rheumatoid arthritis	17
Pseudohyperglycemia due to glucometer interference in galactosemia	17
Procalcitonin measured by three different assays is an excellent tumor marker for the follow-up of patients with medullary thyroid carcinoma	17
Linearity assessment: deviation from linearity and residual of linear regression approaches	17
The role of analytical performance specifications in international guidelines and standards dealing with metrological traceability in laboratory medicine	17
External quality assurance (EQA): navigating between quality and sustainability	17
HTA model for laboratory medicine technologies: overview of approaches adopted in some international agencies	17
Clinical evidence requirements according to the IVDR 2017/746: practical tools and references for underpinning clinical evidence of IVD-MDs	17
Artificial intelligence in clinical applications for lung cancer: diagnosis, treatment and prognosis	17
Refining within-subject biological variation estimation using routine laboratory data: practical applications of the refineR algorithm	17
Inherited disorders, metabolic disorders and rare diseases	16
Comparison between polynomial regression and weighted least squares regression analysis for verification of analytical measurement range	16
Comparison of three different protocols for obtaining hemolysis	16
Lot variation and inter-device differences contribute to poor analytical performance of the DCA Vantage™ HbA1c POCT instrument in a true clinical setting	16
‘Penelope test’: a practical instrument for checking appropriateness of laboratory tests	16
Frontmatter	16
Evaluation of the interchangeability between the new fully-automated affinity chrome-mediated immunoassay (ACMIA) and the Quantitative Microsphere System (QMS) with a CE-IVD-certified LC-MS/MS assay f	16
Diabetes, obesity, metabolic syndrome	16
Differences between high-sensitivity cardiac troponin T and I in stable populations: underlying causes and clinical implications	16
Validation and verification framework and data integration of biosensors and in vitro diagnostic devices: a position statement of the IFCC Committee on Mobile Health and Bioengineering in Labor	16
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of carbamazepine-10,11-epoxide in human serum an	16
The first case of Teclistamab interference with serum electrophoresis and immunofixation	15
Lot-to-lot reagent verification: challenges and possible solutions	15
Estimation of the reference values and decision limits for growth hormone in newborns using dried blood spots	15
Evaluation of reference intervals for classical and alternative pathway functional complement assays	15
Frontmatter	15
The biological variation of insulin resistance markers: data from the European Biological Variation Study (EuBIVAS)	15
Artificial intelligence - Informatics	15
Copeptin as a diagnostic and prognostic biomarker in pediatric diseases	15
A new milestone on the road to global standardization of apolipoprotein measurements	15
Accurate stratification between VEXAS syndrome and differential diagnoses by deep learning analysis of peripheral blood smears	15
The role of Killer immunoglobulin-like receptors (KIRs) in the genetic susceptibility to non-celiac wheat sensitivity (NCWS)	15
A physio-chemical mathematical model of the effects of blood analysis delay on acid-base, metabolite and electrolyte status: evaluation in blood from critical care patients	15
Clinical evaluation of the OC-Sensor Pledia calprotectin assay	15
Frontmatter	15
Annual meeting of the Royal Belgian Society of Laboratory Medicine: “Symphony of the Heart”	15
Performance evaluation and user experience of BT-50 transportation unit with automated and scheduled quality control measurements	14
Improving regional medical laboratory center report quality through a report recall management system	14
Limitations of glycated albumin standardization when applied to the assessment of diabetes patients	14
Serous body fluid evaluation using the new automated haematology analyser Mindray BC-6800Plus	14
The preanalytical process in the emergency department, a European survey	14
Urine transfer devices may impact urinary particle results: a pre-analytical study	14
Association of prehospital lactate levels with base excess in various emergencies – a retrospective study	14
Reply to: “Accurate predictory role of monocyte distribution width on short-term outcome in sepsis patients”	14
Assessing the clinical applicability of dimensionality reduction algorithms in flow cytometry for hematologic malignancies	13
Is it feasible for European laboratories to use SI units in reporting results?	13
A randomized controlled study of biochemical tests in primary care: interventions can reduce the number of tests but usage does not become more appropriate	13
Rare unstable and low oxygen affinity haemoglobin variant, Hb Hazebrouck, detected on Sysmex XN-9000	13
New concept of interactive academic poster used in medical scientific congress presented in the EuroMedLab 2021 Munich Session	13
Comparison of the analytical performance of the PATHFAST high sensitivity cardiac troponin I using fresh whole blood vs. fresh plasma samples	13
Assessment of the humoral response in Omicron breakthrough cases in healthcare workers who received the BNT162b2 booster	13
Kidney diseases	13
Acknowledgment	13
Haematology, including haemostasis	13
Flow-cytometric lymphocyte subsets enumeration: comparison of single/dual-platform method in clinical laboratory with dual-platform extended PanLeucogating method in reference laboratory	13
In-house diagnostic devices under the EU IVDR and unwanted side-effects of intentional transparency	13
Understanding the limitations of your assay using EQA data with serum creatinine as an example	13
Spike vs. nucleocapsid serum antigens for COVID-19 diagnosis and severity assessment	13
Transport stability profiling – a proposed generic protocol	13
Review and evolution of guidelines for diagnosis of COVID-19 vaccine induced thrombotic thrombocytopenia (VITT)	12
Clinical implication by differential analytical performances of serum free light chain quantitation analysis using fully automated analyzers	12
Preanalytical phase	12
Evidence-based procedures to improve the reliability of circulating miRNA biomarker assays	12
Ct values of different SARS CoV2 variants: a single center observational study from Innsbruck, Austria	12
Novel protocol for metabolomics data normalization and biomarker discovery in human tears	12
Low serum TSH in the acute phase of COVID-19 pneumonia: thyrotoxicosis or a face of “non-thyroidal illness syndrome”?	12
Diagnosis of IRAK-4-deficiency by flow cytometric measurement of IκB-α degradation	12
Setting analytical performance specifications for copeptin-based testing	12
Kinetics and ability of binding antibody and surrogate virus neutralization tests to predict neutralizing antibodies against the SARS-CoV-2 Omicron variant following BNT162b2 booster administration	12
Inconsistency in ferritin reference intervals across laboratories: a major concern for clinical decision making	12
The routine coagulation assays plasma stability – in the wake of the new European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) biological variability database	12
Reference intervals of circulating secretoneurin concentrations determined in a large cohort of community dwellers: the HUNT study	12
Variations in tumor growth, intra-individual biological variability, and the interpretation of changes	12
Precise glucose measurement in sodium fluoride-citrate plasma affects estimates of prevalence in diabetes and prediabetes	12
Diagnostic accuracy of extended HPV DNA genotyping and its application for risk-based cervical cancer screening strategy	12

Testosterone analysis in castrated prostate cancer patients: suitability of the castration cut-off and analytical accuracy of the present-day clinical immunoassays	12
S100B in cardiac surgery brain monitoring: friend or foe?	12
Tumor markers determination in malignant pleural effusion: pearls and pitfalls	12
Striving for a pragmatic contribution of biomarkers results to lifelong health care	12
Six years of progress – highlights from the IFCC Emerging Technologies Division	12
Unraveling the mystery of blood groups and COVID-19	12
Comparison between free β subunit of human chorionic gonadotropin (hCG) and total hCG assays in adults with testicular cancer	11
An approach for determining allowable between reagent lot variation	11
Clostebol detection after transdermal and transmucosal contact. A systematic review	11
Where is laboratory medicine headed in the next decade? Partnership model for efficient integration and adoption of artificial intelligence into medical laboratories	11
Interferences in immunoassays: review and practical algorithm	11
Frontmatter	11
16ª Reunião Científica da Sociedade Portuguesa de Medicina Laboratorial - SPML	11
Chemical strategies for sustainable medical laboratories	11
SARS CoV-2 spike protein-guided exosome isolation facilitates detection of potential miRNA biomarkers in COVID-19 infections	11
A survey on Artificial Intelligence and Big Data utilisation in Italian clinical laboratories	11
A model for managing quality control for a network of clinical chemistry instruments measuring the same analyte	11
Sepsis	11
Diagnostic accuracy of adenosine deaminase for tuberculous pleural effusion: age does matter	11
Impact of different preservation methods on urinary red blood cell counts	11
C-terminal alpha-1-antitrypsin peptides as novel predictor of hospital mortality in critically ill COVID-19 patients	11
Improved implementation of medical tests – barriers and opportunities	11
Evidence for stability of cardiac troponin T concentrations measured with a high sensitivity TnT test in serum and lithium heparin plasma after six-year storage at −80 °C and multiple freeze-thaw cycl	11
Performance evaluation of the introduction of full sample traceability system within the specimen collection process	11
Estimation of the allowable total error of the absolute CD34+ cell count by flow cytometry using data from UK NEQAS exercises 2004–2024	11
Symposium 13 - Prenatal testing	11
Neurological diseases	11
Frontmatter	11
Within- and between-subject biological variation data for tumor markers based on the European Biological Variation Study	10
Ageing, ACE2 deficiency and bad outcome in COVID-19	10
Patient risk management in laboratory medicine: an international survey to assess the severity of harm associated with erroneous reported results	10
Analytical and clinical evaluations of Snibe Maglumi® S100B assay	10
Is uracil enough for effective pre-emptive DPD testing?	10
Measuring accuracy of the neutralizing activity of COVID-19 convalescent plasma	10
Positivization time of a COVID-19 rapid antigen self-test predicts SARS-CoV-2 viral load: a proof of concept	10
Laboratory Management, Accreditation, Quality Assurance, performance specification	10
Can we identify patients carrying targeted deleterious DPYD variants with plasma uracil and dihydrouracil? A GPCO-RNPGx retrospective analysis	10
Using artificial intelligence in a primary care setting to identify patients at risk for cancer: a risk prediction model based on routine laboratory tests	10
Clearance of macro-TSH from the circulation is slower than TSH	10
Pre-analytical recommendations and reference values for circulating calprotectin are sample type and assay dependent	10
An appeal for biological variation estimates in deep immunophenotyping	10
Traceable machine learning real-time quality control based on patient data	10
The total testing process harmonization: the case study of SARS-CoV-2 serological tests	10
The effects of drone transportation on routine laboratory, immunohematology, flow cytometry and molecular analyses	10
First-trimester screening for Down syndrome using quadruple maternal biochemical markers	10
Spurious parathyroid hormone (PTH) elevation caused by macro-PTH	10
External quality assessment of serum indices: Spanish SEQC-ML program	10
Role of ACE2 polymorphism in COVID-19: impact of age	10
A screening method to spot biomarkers that may warn of serious events in a chronic disease – illustrated by cardiological CLARICOR trial data	10
Method comparison of three serum free light chain assays on the Roche Cobas 6000 c501 chemistry analyzer	10
M-protein diagnostics in multiple myeloma patients using ultra-sensitive targeted mass spectrometry and an off-the-shelf calibrator	10
Association of circulating free and total oxysterols in breast cancer patients	10
An appraisal of the practice of duplicate testing for the detection of irregular analytical errors	9
Practical delta check limits for tumour markers in different clinical settings	9
Lot-to-lot bias for high-sensitivity cardiac troponin I concentrations ≥1000 ng/L	9
Is this a true lambda free light chain?	9
Endocrinology, not including diabetes	9
Evaluation of the Atellica TnIH cardiac troponin I assay and assessment of biological equivalence	9
Diagnostic quality model (DQM): an integrated framework for the assessment of diagnostic quality when using AI/ML	9
Commercial immunoassays for detection of anti-SARS-CoV-2 spike and RBD antibodies: urgent call for validation against new and highly mutated variants	9
Diagnostic performance of Mindray CL1200i high sensitivity cardiac troponin I assay compared to Abbott Alinity cardiac troponin I assay for the diagnosis of type 1 and 2 acute myocardial infarction in	9
Use of high-sensitivity cardiac troponins in the emergency department for the early rule-in and rule-out of acute myocardial infarction without persistent ST-segment elevation (NSTEMI) in Italy	9
Analytical performance specifications based on biological variation data – considerations, strengths and limitations	9
Committees	9
Harmonization of indirect reference intervals calculation by the Bhattacharya method	9
Development of an inverse-PCR approach for characterization of the major BCR-ABL1 breakpoint sequences on genomic DNA: proof of concept	9
IFCC Symposium - Advancing Excellence in Laboratory Medicine Worldwide: An Update from IFCC Taskforces	9
Discrepancies in PSA values among laboratories: the case of a traveling patient	9
Serum biomarkers of remodeling in severe asthma with fixed airway obstruction and the potential role of KL-6	9
The simple reproducibility of a measurement result does not equal its overall measurement uncertainty	9
An overview of the most important preanalytical factors influencing the clinical performance of SARS-CoV-2 antigen rapid diagnostic tests (Ag-RDTs)	9
The journey to pre-analytical quality	9
Laboratory medicine unveiling an unusual cause of D-lactic acidosis as the trigger of decompensation of a rare inborn error of metabolism	9
Early changes in S100B maternal blood levels can predict fetal intrauterine growth restriction	9
Fifty years of newborn screening for congenital hypothyroidism: current status in Australasia and the case for harmonisation	9
Added value of drug-laboratory test interaction alerts in test result authorisation	9
Biotin interference in immunoassays: water under the bridge?	9
Prognostic significance of blood-based multi-cancer detection in plasma cell-free DNA	9
Tutorial: statistical methods for the meta-analysis of diagnostic test accuracy studies	9
Searching for the urine osmolality surrogate: an automated machine learning approach	9
Correction of negative-interference from calcium dobesilate in the Roche sarcosine oxidase creatinine assay using CuO	9
Biological variation of serum iron from the European biological variation study (EuBIVAS)	9
Clinical cases – Preanalytical mysteries	8
Cardiovascular diseases and cardiac biomarkers	8
Toxicology, including therapeutic drug monitoring	8
Get reliable laboratory findings – how to recognize the deceptive effects of angiotensin-converting enzyme inhibitor therapy in the laboratory diagnostics of sarcoidosis?	8
4th National Point of Care Testing Symposium	8
Impact of storage temperature and time before analysis on electrolytes (Na+, K+, Ca2+), lactate, glucose, blood gases (pH, pO2, pCO2), tHb, O	8
Long-term stability of 25-hydroxyvitamin D: importance of the analytical method and of the patient matrix	8
The European Register of Specialists in Clinical Chemistry and Laboratory Medicine: code of conduct, version 3 – 2023	8
Anti-Ki/anti-PA28γ autoantibodies contribute to the HEp-2 indirect immunofluorescence nuclear speckled pattern	8
Miscellaneous	8
Comparison of the QuikRead go® point-of-care faecal immunochemical test for haemoglobin with the FOB Gold Wide® laboratory analyser to diagnose colorectal cancer in symptomatic p	8
EFLM Symposium - Precision Medicine	8
C-reactive protein interacts with amphotericin B liposomes and its potential clinical consequences	8