OOIR: Observatory of International Research

Papers

(The TQCC of Biological Chemistry is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Antibody display technologies: selecting the cream of the crop	78
3-Mercaptopyruvate sulfurtransferase: an enzyme at the crossroads of sulfane sulfur trafficking	56
Kill one or kill the many: interplay between mitophagy and apoptosis	47
Shifting paradigms and novel players in Cys-based redox regulation and ROS signaling in plants - and where to go next	47
Regulation of DEAH-box RNA helicases by G-patch proteins	44
Acute-phase protein synthesis: a key feature of innate immune functions of the liver	44
Human islet amyloid polypeptide (hIAPP) - a curse in type II diabetes mellitus: insights from structure and toxicity studies	37
Metabolism of non-growing bacteria	36
Thiol switches in membrane proteins - Extracellular redox regulation in cell biology	35
The role of very long chain fatty acids in yeast physiology and human diseases	34
Unexpected metabolic versatility among type II methanotrophs in the Alphaproteobacteria	34
Glutaredoxins and iron-sulfur protein biogenesis at the interface of redox biology and iron metabolism	32
Thiol-based redox switches in the major pathogen Staphylococcus aureus	32
Emerging roles for non-selenium containing ER-resident glutathione peroxidases in cell signaling and disease	31
The ups and downs of ectoine: structural enzymology of a major microbial stress protectant and versatile nutrient	31
Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins	31
Brothers in arms: proBDNF/BDNF and sAPPα/Aβ-signaling and their common interplay with ADAM10, TrkB, p75NTR, sortilin, and sorLA in the progression of Alzheimer’s disease	28
Redox-dependent and independent effects of thioredoxin interacting protein	25
Redox regulation in host-pathogen interactions: thiol switches and beyond	24
Starting the engine of the powerhouse: mitochondrial transcription and beyond	24
Glutamine synthetase as a central element in hepatic glutamine and ammonia metabolism: novel aspects	24
RNA secondary structure dependence in METTL3–METTL14 mRNA methylation is modulated by the N-terminal domain of METTL3	24
Multicellular and unicellular responses of microbial biofilms to stress	23
Chemerin – exploring a versatile adipokine	23
Myricetin protects pancreatic β-cells from human islet amyloid polypeptide (hIAPP) induced cytotoxicity and restores islet function	22

A guide to designing photocontrol in proteins: methods, strategies and applications	21
Diversity of GPI-anchored fungal adhesins	21
Pathomechanisms in hepatic encephalopathy	21
Biosynthesis and function of cell-surface polysaccharides in the social bacterium Myxococcus xanthus	20
Regulation of RNA helicase activity: principles and examples	20
Detecting myocardial scar using electrocardiogram data and deep neural networks	20
Hsa-miR-186-5p regulates TGFβ signaling pathway through expression suppression of SMAD6 and SMAD7 genes in colorectal cancer	19
Membrane damage and repair: a thin line between life and death	19
A primer on heme biosynthesis	19
Investigation of the structure of regulatory proteins interacting with glycosaminoglycans by combining NMR spectroscopy and molecular modeling – the beginning of a wonderful friendship	19
LOTUS-domain proteins - developmental effectors from a molecular perspective	18
Collagen/glycosaminoglycan-based matrices for controlling skin cell responses	18
Hepatic stellate cells: current state and open questions	18
Biochemical unity revisited: microbial central carbon metabolism holds new discoveries, multi-tasking pathways, and redundancies with a reason	17
Dead or alive: DEAD-box ATPases as regulators of ribonucleoprotein complex condensation	17
iMLP, a predictor for internal matrix targeting-like sequences in mitochondrial proteins	16
The DEAH helicase DHX36 and its role in G-quadruplex-dependent processes	16
Post-translational lysine ac(et)ylation in health, ageing and disease	16
Cyclic di-GMP signaling controlling the free-living lifestyle of alpha-proteobacterial rhizobia	15
Transfer RNA processing – from a structural and disease perspective	15
Revisiting the interaction of heme with hemopexin	15
Thiol-based switching mechanisms of stress-sensing chaperones	15
Generating asymmetry in a changing environment: cell cycle regulation in dimorphic alphaproteobacteria	14
STAT3 promotes peritoneal metastasis of gastric cancer by enhancing mesothelial-mesenchymal transition	14
Regulation of RNA stability at the 3′ end	14
TFAP2A-induced SLC2A1-AS1 promotes cancer cell proliferation	14
Targeting spectrin redox switches to regulate the mechanoproperties of red blood cells	14
Irisin ameliorates endoplasmic reticulum stress and liver fibrosis through inhibiting PERK-mediated destabilization of HNRNPA1 in hepatic stellate cells	14
New insights into the role of glycosaminoglycans in the endosteal bone microenvironment	14
The role of mycotoxins in neurodegenerative diseases: current state of the art and future perspectives of research	13
Heme delivery to heme oxygenase-2 involves glyceraldehyde-3-phosphate dehydrogenase	13
Genetically encoded thiol redox-sensors in the zebrafish model: lessons for embryonic development and regeneration	13
Chemically modified glycosaminoglycan derivatives as building blocks for biomaterial coatings and hydrogels	13
Mtr4 RNA helicase structures and interactions	12
HDAC8 promotes daunorubicin resistance of human acute myeloid leukemia cells via regulation of IL-6 and IL-8	12
Structures and nucleic acid-binding preferences of the eukaryotic ARID domain	12
Genomic insights into cyanobacterial protein translocation systems	12
Expansion and inflammation of white adipose tissue - focusing on adipocyte progenitors	11
Thioredoxin-dependent control balances the metabolic activities of tetrapyrrole biosynthesis	11
New roles for GAPDH, Hsp90, and NO in regulating heme allocation and hemeprotein function in mammals	11
Elucidating the anti-biofilm and anti-quorum sensing potential of selenocystine against respiratory tract infections causing bacteria: in vitro and in silico studies	10
Improvement of wound healing by the development of ECM-inspired biomaterial coatings and controlled protein release	10
DDX41: a multifunctional DEAD-box protein involved in pre-mRNA splicing and innate immunity	10
Pseudomonas aeruginosa and Staphylococcus aureus virulence factors as biomarkers of infection	10
Structural insights into the modulation of PDGF/PDGFR-β complexation by hyaluronan derivatives	10
Emerging contributions of formyl peptide receptors to neurodegenerative diseases	10
Molecular insights into endolysosomal microcompartment formation and maintenance	10
The emerging role of ATP as a cosolute for biomolecular processes	10
CERKL alleviates ischemia reperfusion-induced nervous system injury through modulating the SIRT1/PINK1/Parkin pathway and mitophagy induction	10
Rational approaches towards inorganic and organometallic antibacterials	10

PCAT1 induced by transcription factor YY1 promotes cholangiocarcinoma proliferation, migration and invasion by sponging miR-216a-3p to up-regulate oncogene BCL3	10
Spatial organization enhances versatility and specificity in cyclic di-GMP signaling	10
Regulation of transforming growth factor-β1-stimulation of Runx2 acetylation for matrix metalloproteinase 13 expression in osteoblastic cells	10
Physiology of guanosine-based second messenger signaling in Bacillus subtilis	9
Role of the gut microbiota in airway immunity and host defense against respiratory infections	9
Individual and combined effects of GIP and xenin on differentiation, glucose uptake and lipolysis in 3T3-L1 adipocytes	9
Assessment of the breadth of binding promiscuity of heme towards human proteins	9
Molecular mechanisms of vasculopathy and coagulopathy in COVID-19	9
Placental mitochondrial function as a driver of angiogenesis and placental dysfunction	9
C-X-C chemokine receptor 2 (Cxcr2) promotes hepatocellular carcinoma immune evasion via regulating programmed death-ligand 1 (PD-L1)	9
Zinc-dependent changes in oxidative and endoplasmic reticulum stress during cardiomyocyte hypoxia/reoxygenation	9
Exceptionally versatile take II: post-translational modifications of lysine and their impact on bacterial physiology	9
The paracaspase MALT1 in psoriasis	9
Berberine improves dietary-induced cardiac remodeling by upregulating Kruppel-like factor 4-dependent mitochondrial function	9
Modulation of macrophage functions by ECM-inspired wound dressings – a promising therapeutic approach for chronic wounds	9
Eukaryotic tRNA splicing – one goal, two strategies, many players	9
The role of host heme in bacterial infection	9
Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies	9
The phytochemical plumbagin reciprocally modulates osteoblasts and osteoclasts	8
The role of the Na⁺/Ca²⁺-exchanger (NCX) in cancer-associated fibroblasts	8
Effect of myeloperoxidase oxidation and N-homocysteinylation of high-density lipoprotein on endothelial repair function	8
Identification of cytokeratin24 as a tumor suppressor for the management of head and neck cancer	8
Transcription, translation, and DNA repair: new insights from emerging noncanonical substrates of RNA helicases	8
Epithelial-mesenchymal transition and H₂O₂ signaling – a driver of disease progression and a vulnerability in cancers	8
High cellulose diet promotes intestinal motility through regulating intestinal immune homeostasis and serotonin biosynthesis	8
Vorinostat exhibits anticancer effects in triple-negative breast cancer cells by preventing nitric oxide-driven histone deacetylation	8
The relevance of adhesion G protein-coupled receptors in metabolic functions	8
Apolipoprotein C-II and C-III preferably transfer to both high-density lipoprotein (HDL)₂ and the larger HDL₃ from very low-density lipoprotein (VLDL)	8
Interaction of nucleoporins with nuclear transport receptors: a structural perspective	8
Characterization of a fluorescent 1,8-naphthalimide-functionalized PAMAM dendrimer and its Cu(ii) complexes as cytotoxic drugs: EPR and biological studies in myeloid tumor cells	8
Decreased level of miR-1301 promotes colorectal cancer progression via activation of STAT3 pathway	8
Histone deacetylase 1 regulates the malignancy of oral cancer cells via miR-154-5p/PCNA axis	8
The extracellular region of bovine milk butyrophilin exhibits closer structural similarity to human myelin oligodendrocyte glycoprotein than to immunological BTN family receptors	8
Infection, inflammation and thrombosis: a review of potential mechanisms mediating arterial thrombosis associated with influenza and severe acute respiratory syndrome coronavirus 2	8