OOIR: Observatory of International Research

Papers

(The TQCC of Biological Chemistry is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation and probing NOX4 interactions via molecular docking	57
Frontmatter	40
LncRNA-p21 suppresses cell proliferation and induces apoptosis in gastric cancer by sponging miR-514b-3p and up-regulating ARHGEF9 expression	34
Frontmatter	31
Frontmatter	31
Astrocytic potassium and calcium channels as integrators of the inflammatory and ischemic CNS microenvironment	30
Yme2, a putative RNA recognition motif and AAA+ domain containing protein, genetically interacts with the mitochondrial protein export machinery	27
Infection, inflammation and thrombosis: a review of potential mechanisms mediating arterial thrombosis associated with influenza and severe acute respiratory syndrome coronavirus 2	26
Highlight: young research groups in Germany – 5th edition	26
Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation	24
SRPK1 promotes cell proliferation and tumor growth of osteosarcoma through activation of the NF-κB signaling pathway	21
Synthesis and biological characterization of a new fluorescent probe for vesicular trafficking based on polyazamacrocycle derivative	20
Characterization of the scavenger cell proteome in mouse and rat liver	20
Altered population activity and local tuning heterogeneity in auditory cortex of Cacna2d3-deficient mice	18
Anti-inflammatory dihydroxanthones from a Diaporthe species	17
Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity	16
Diselenide-derivative of 3-pyridinol targets redox enzymes leading to cell cycle deregulation and apoptosis in A549 cells	16
Exceptionally versatile take II: post-translational modifications of lysine and their impact on bacterial physiology	15
Development of an enabling platform biotechnology for the production of proteins	15
Mechanism of hypoxia-induced exosome circ_0051799 regulating the progression of lung adenocarcinoma	14
Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase	14
Molecular determinants of health and disease	14
Computational resolution in single molecule localization – impact of noise level and emitter density	14
Functional characterisation of two receptor interaction determinants in human thymic stromal lymphopoietin	14
Frontmatter	13

Broadened substrate specificity of bacterial dipeptidyl-peptidase 7 enables release of half of all dipeptide combinations from peptide N-termini	13
Protein transport along the presequence pathway	13
The Mycobacterium tuberculosis prolyl dipeptidyl peptidase cleaves the N-terminal peptide of the immunoprotein CXCL-10	13
Implications of TRPM3 and TRPM8 for sensory neuron sensitisation	13
Influence of inflammatory processes on thalamocortical activity	13
Molecular determinants of protein half-life in chloroplasts with focus on the Clp protease system	12
Highlight: structure and function of the peroxisomal translocon	12
Simultaneous spectral illumination of microplates for high-throughput optogenetics and photobiology	12
The cAMP responsive element modulator (CREM) is a regulator of CD4⁺ T cell function	12
Unpaired cysteine insertions favor transmembrane dimerization and induce ligand-independent constitutive cytokine receptor signaling	12
Machine learning based disease prediction from genotype data	11
Chemically modified glycosaminoglycan derivatives as building blocks for biomaterial coatings and hydrogels	11
Dynamics of the translocation pore of the human peroxisomal protein import machinery	11
Frontmatter	11
Comparative studies of soluble and immobilized Fe(III) heme-peptide complexes as alternative heterogeneous biocatalysts	11
Highlights in biochemistry Bochum 2022	11
Characterization of hepatic zonation in mice by mass-spectrometric and antibody-based proteomics approaches	11
Protein engineering & design: hitting new heights	10
Frontmatter	10
Apolipoprotein E-containing lipoproteins and their extracellular interactions with LRP1 affect LPS-induced inflammation	10
Methionine restriction attenuates the migration and invasion of gastric cancer cells by inhibiting nuclear p65 translocation through TRIM47	10
Detection of a 7SL RNA-derived small non-coding RNA using Molecular Beacons in vitro and in cells	10
Structure and phase separation of the C-terminal domain of RNA polymerase II	10
A tailored cytochrome P450 monooxygenase from Gordonia rubripertincta CWB2 for selective aliphatic monooxygenation	10
Decreased level of miR-1301 promotes colorectal cancer progression via activation of STAT3 pathway	10
Functional genomics meta-analysis to identify gene set enrichment networks in cardiac hypertrophy	9
The nascent polypeptide-associated complex (NAC) as regulatory hub on ribosomes	9
Protein kinase CK2 contributes to glucose homeostasis	9
Dynamic phospho-modification of viral proteins as a crucial regulatory layer of influenza A virus replication and innate immune responses	9
The phytochemical plumbagin reciprocally modulates osteoblasts and osteoclasts	9
Structures and nucleic acid-binding preferences of the eukaryotic ARID domain	9
Role of the gut microbiota in airway immunity and host defense against respiratory infections	9
The role of the Na⁺/Ca²⁺-exchanger (NCX) in cancer-associated fibroblasts	8
Insights in caveolae protein structure arrangements and their local lipid environment	8
Highlight: new developments in immunoengineering	8
Tumor cell lysis and synergistically enhanced antibody-dependent cell-mediated cytotoxicity by NKG2D engagement with a bispecific immunoligand targeting the HER2 antigen	8
The Zika virus infection remodels the expression of the synaptotagmin-9 secretory protein	8
Structural insights into the repair mechanism of AGT for methyl-induced DNA damage	8
The role of ADAM17 during liver damage	8
Inhibition of miR-143-3p alleviates myocardial ischemia reperfusion injury via limiting mitochondria-mediated apoptosis	8
Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins	8
KCTD5 regulates Ikaros degradation induced by chemotherapeutic drug etoposide in hematological cells	8
In vitro ADME characterization of a very potent 3-acylamino-2-aminopropionic acid-derived GluN2C-NMDA receptor agonist and its ester prodrugs	8
The emerging role of ATP as a cosolute for biomolecular processes	8
Structural basis of Alzheimer β-amyloid peptide recognition by engineered lipocalin proteins with aggregation-blocking activity	7
Frontmatter	7
Unfolded protein responses in Chlamydomonas reinhardtii	7
Frontmatter	7
Frontmatter	7
A liquid-culture-based screening approach to study compounds affecting inflammatory processes in Caenorhabditis elegans	7

Improvement of wound healing by the development of ECM-inspired biomaterial coatings and controlled protein release	7
Eukaryotic tRNA splicing – one goal, two strategies, many players	7
Microtubules as a signal hub for axon growth in response to mechanical force	7
Small-molecule metabolites in SARS-CoV-2 treatment: a comprehensive review	6
Frontmatter	6
Bioinformatics in theory and application – highlights of the 36th German Conference on Bioinformatics	6
The relevance of adhesion G protein-coupled receptors in metabolic functions	6
Interaction of RTX toxins with the host cell plasma membrane	6
Distinct conformational and energetic features define the specific recognition of (di)aromatic peptide motifs by PEX14	6
Extracellular hemin is a reverse use-dependent gating modifier of cardiac voltage-gated Na⁺ channels	6
Frontmatter	6
A guide to designing photocontrol in proteins: methods, strategies and applications	6
Post-translational lysine ac(et)ylation in health, ageing and disease	6
Unification of functional annotation descriptions using text mining	6
Membrane binding and pore forming insertion of PEX5 into horizontal lipid bilayer	6
Frontmatter	6
Molecular simulations of DEAH-box helicases reveal control of domain flexibility by ligands: RNA, ATP, ADP, and G-patch proteins	6
Extracellular stimulation of lung fibroblasts with arachidonic acid increases interleukin 11 expression through p38 and ERK signaling	6
The paracaspase MALT1 in psoriasis	6
Highlight: how to synthesize, assemble and regulate ribonucleoprotein-complexes	6