OOIR: Observatory of International Research

Papers

(The median citation count of Biological Chemistry is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Frontmatter	47
Frontmatter	37
Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation and probing NOX4 interactions via molecular docking	29
Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation	24
Diversification of glutathione transferases in plants and their role in oxidative stress defense	22
CNKSR2 scaffold function in the mammalian nervous system	21
Altered population activity and local tuning heterogeneity in auditory cortex of Cacna2d3 -deficient mice	20
Highlight: young research groups in Germany – 5th edition	20
Development of an enabling platform biotechnology for the production of proteins	20
LncRNA-p21 suppresses cell proliferation and induces apoptosis in gastric cancer by sponging miR-514b-3p and up-regulating ARHGEF9 expression	20
Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity	19
Development of kallikrein-related peptidase 7 (KLK7) inhibitors and use in a species-adapted model for ovarian cancer	19
Mechanism of hypoxia-induced exosome circ_0051799 regulating the progression of lung adenocarcinoma	18
Diselenide-derivative of 3-pyridinol targets redox enzymes leading to cell cycle deregulation and apoptosis in A549 cells	17
The Mycobacterium tuberculosis prolyl dipeptidyl peptidase cleaves the N-terminal peptide of the immunoprotein CXCL-10	16
Protein transport along the presequence pathway	15
Implications of TRPM3 and TRPM8 for sensory neuron sensitisation	15
Computational resolution in single molecule localization – impact of noise level and emitter density	15
Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase	14
Broadened substrate specificity of bacterial dipeptidyl-peptidase 7 enables release of half of all dipeptide combinations from peptide N-termini	13
Influence of inflammatory processes on thalamocortical activity	13
Highlight: structure and function of the peroxisomal translocon	12
Frontmatter	12
Unpaired cysteine insertions favor transmembrane dimerization and induce ligand-independent constitutive cytokine receptor signaling	12
Highlights in biochemistry Bochum 2022	12

Detection of a 7SL RNA-derived small non-coding RNA using Molecular Beacons in vitro and in cells	12
Frontmatter	12
Molecular determinants of protein half-life in chloroplasts with focus on the Clp protease system	11
Dynamics of the translocation pore of the human peroxisomal protein import machinery	11
Methionine restriction attenuates the migration and invasion of gastric cancer cells by inhibiting nuclear p65 translocation through TRIM47	11
Comparative studies of soluble and immobilized Fe(III) heme-peptide complexes as alternative heterogeneous biocatalysts	11
Simultaneous spectral illumination of microplates for high-throughput optogenetics and photobiology	11
Pathogenic missense variants of CSNK2B associated with Poirier-Bienvenu neurodevelopmental disorder impact differently on CK2 holoenzyme formation	11
A tailored cytochrome P450 monooxygenase from Gordonia rubripertincta CWB2 for selective aliphatic monooxygenation	11
Sarcomere analysis in human cardiomyocytes by computing radial frequency spectra	10
Protein kinase CK2 contributes to glucose homeostasis	10
Apolipoprotein E-containing lipoproteins and their extracellular interactions with LRP1 affect LPS-induced inflammation	10
Inhibition of miR-143-3p alleviates myocardial ischemia reperfusion injury via limiting mitochondria-mediated apoptosis	10
The nascent polypeptide-associated complex (NAC) as regulatory hub on ribosomes	10
Frontmatter	10
The Zika virus infection remodels the expression of the synaptotagmin-9 secretory protein	10
Structure and phase separation of the C-terminal domain of RNA polymerase II	10
The role of the Na⁺/Ca²⁺-exchanger (NCX) in cancer-associated fibroblasts	9
In vitro ADME characterization of a very potent 3-acylamino-2-aminopropionic acid-derived GluN2C-NMDA receptor agonist and its ester prodrugs	9
Insights in caveolae protein structure arrangements and their local lipid environment	9
The emerging role of ATP as a cosolute for biomolecular processes	9
Frontmatter	9
Glue it together: self-assembly of the antibacterial GTPase GBP1	9
KCTD5 regulates Ikaros degradation induced by chemotherapeutic drug etoposide in hematological cells	9
Highlight: new developments in immunoengineering	9
Conserved function, divergent evolution: mitochondrial outer membrane insertases across eukaryotes	9
Membrane binding and pore forming insertion of PEX5 into horizontal lipid bilayer	8
Interaction of RTX toxins with the host cell plasma membrane	8
Eukaryotic tRNA splicing – one goal, two strategies, many players	8
Unfolded protein responses in Chlamydomonas reinhardtii	8
Distinct conformational and energetic features define the specific recognition of (di)aromatic peptide motifs by PEX14	8
Extracellular hemin is a reverse use-dependent gating modifier of cardiac voltage-gated Na⁺ channels	8
Highlight: how to synthesize, assemble and regulate ribonucleoprotein-complexes	8
Frontmatter	8
Frontmatter	8
Molecular simulations of DEAH-box helicases reveal control of domain flexibility by ligands: RNA, ATP, ADP, and G-patch proteins	8
Pathological and physiological roles of ADP-ribosylation: established functions and new insights	8
Small-molecule metabolites in SARS-CoV-2 treatment: a comprehensive review	8
The heart of the matter: a personal view of Fred Wittinghofer’s contributions to RAS biology and drug design	8
Microtubules as a signal hub for axon growth in response to mechanical force	8
The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase	7
GAP mimetic activity of pan-Ras TCI daraxonrasib synergizes with K-Ras Switch-II pocket inhibition	7
CK2 control of human papillomavirus life cycles	7
Rodent models for mood disorders – understanding molecular changes by investigating social behavior	7
The evolution and diversification of the Hsp90 co-chaperone system	7
Protein persulfidation in plants: mechanisms and functions beyond a simple stress response	7
Extracellular stimulation of lung fibroblasts with arachidonic acid increases interleukin 11 expression through p38 and ERK signaling	7
Endocytic scaffolds at the crossroads of Alzheimer’s disease and neuronal aging	7
Cell-type specific anti-cancerous effects of nitro-oleic acid and its combination with gamma irradiation	7
Study of two glycosyltransferases related to polysaccharide biosynthesis in Rhodococcus jostii RHA1	7

Modulation of self-organizing circuits at deforming membranes by intracellular and extracellular factors	6
Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features	6
The 76th Mosbacher Colloquium: AI-driven (r)evolution in structural biology and protein design	6
Highlight: on the past and the future of cellular microcompartments	6
MicroRNA-6838-5p suppresses the self-renewal and metastasis of human liver cancer stem cells through downregulating CBX4 expression and inactivating ERK signaling	6
The promise of genetic screens in human in vitro brain models	6
NF90/NFAR (nuclear factors associated with dsRNA) – a new methylation substrate of the PRMT5-WD45-RioK1 complex	6
Interaction of nucleoporins with nuclear transport receptors: a structural perspective	6
The mitochondrial intermembrane space – a permanently proteostasis-challenged compartment	5
LINC00858 facilitates formation of hepatic metastases from colorectal cancer via regulating the miR-132-3p/IGF2BP1 axis	5
Illuminating the brain-genetically encoded single wavelength fluorescent biosensors to unravel neurotransmitter dynamics	5
The second PI(3,5)P₂ binding site in the S0 helix of KCNQ1 stabilizes PIP₂-at the primary PI1 site with potential consequences on intermediate-to-open state transit	5
Celastrol inhibits angiogenesis and the biological processes of MDA-MB-231 cells via the DEGS1/S1P signaling pathway	5
Cathepsin L-mediated EGFR cleavage affects intracellular signalling pathways in cancer	5
Frontmatter	5
Getting to the right place at the right time – membrane trafficking and maturation in the endolysosomal system	5
Frontmatter	5
Transfer RNA processing – from a structural and disease perspective	5
Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2	5
Investigation of the P1′ and P2′ sites of IQF substrates and their selectivity toward 20S proteasome subunits	5
Analysis of cell cycle stage, replicated DNA, and chromatin-associated proteins using high-throughput flow cytometry	5
Fred Wittinghofer and the GTP/GDP-binding proteins	4
M2 macrophages-derived exosomal miR-3917 promotes the progression of lung cancer via targeting GRK6	4
Structure and function of spliceosomal DEAH-box ATPases	4
Intersectins as versatile scaffolds for membrane-associated processes	4
Frontmatter	4
Adherens junctions balance stability and motility: from cell morphogenesis to neural tissue patterning	4
The role of PDE6D in trafficking KRAS	4
Interactions of Na⁺/taurocholate cotransporting polypeptide with host cellular proteins upon hepatitis B and D virus infection: novel potential targets for antiviral therapy	4
Inhibition of Chk1 stimulates cytotoxic action of platinum-based drugs and TRAIL combination in human prostate cancer cells	4
A CK2α′ mutant indicating why CK2α and CK2α′, the isoforms of the catalytic subunit of human protein kinase CK2, deviate in affinity to CK2β	4
New lipophilic organic nitrates: candidates for chronic skin disease therapy	4
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis	4
Frontmatter	4
The many faces of ribosome translocation along the mRNA: reading frame maintenance, ribosome frameshifting and translational bypassing	4
Highlight: chemical biology of ion channels	4
Neprilysin 4: an essential peptidase with multifaceted physiological relevance	4
Mycobacterial type VII secretion systems	4
Autophagic and non-autophagic functions of the Saccharomyces cerevisiae PROPPINs Atg18, Atg21 and Hsv2	4
Unclogging of the TOM complex under import stress	3
Time- and dose-dependent effects of CIGB-300 on the proteome of lung squamous cell carcinoma	3
The proteostasis burden of aneuploidy	3
Stress response pathways: machineries and mechanisms	3
Molecular insights into endolysosomal microcompartment formation and maintenance	3
Biochemical evidence for conformational variants in the anti-viral and pro-metastatic protein IFITM1	3
Heme delivery to heme oxygenase-2 involves glyceraldehyde-3-phosphate dehydrogenase	3
Nanoscale organization of Ca_V2.1 splice isoforms at presynaptic terminals: implications for synaptic vesicle release and synaptic facilitation	3
Posttranslational modifications of RAS: few pockets but many bumps	3
Good things come to those who bait: the peroxisomal docking complex	3
Heme research – the past, the present and the future	3
Synthesis of the ribosomal RNA precursor in human cells: mechanisms, factors and regulation	3
The human long non-coding RNA LINC00941 and its modes of action in health and disease	3
Frontmatter	3
A primer on heme biosynthesis	3
The DEAD-box RNA helicase Dbp5 is a key protein that couples multiple steps in gene expression	3
Frontmatter	3
Features of yeast RNA polymerase I with special consideration of the lobe binding subunits	3
Frontmatter	3