OOIR: Observatory of International Research

Papers

(The median citation count of Biological Chemistry is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Frontmatter	50
Frontmatter	39
Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation and probing NOX4 interactions via molecular docking	31
Highlight: young research groups in Germany – 5th edition	25
LncRNA-p21 suppresses cell proliferation and induces apoptosis in gastric cancer by sponging miR-514b-3p and up-regulating ARHGEF9 expression	23
Frontmatter	22
CNKSR2 scaffold function in the mammalian nervous system	22
Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation	20
Development of an enabling platform biotechnology for the production of proteins	20
Diversification of glutathione transferases in plants and their role in oxidative stress defense	20
Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity	19
Altered population activity and local tuning heterogeneity in auditory cortex of Cacna2d3 -deficient mice	19
Mechanism of hypoxia-induced exosome circ_0051799 regulating the progression of lung adenocarcinoma	17
Development of kallikrein-related peptidase 7 (KLK7) inhibitors and use in a species-adapted model for ovarian cancer	17
Diselenide-derivative of 3-pyridinol targets redox enzymes leading to cell cycle deregulation and apoptosis in A549 cells	17
Computational resolution in single molecule localization – impact of noise level and emitter density	16
The Mycobacterium tuberculosis prolyl dipeptidyl peptidase cleaves the N-terminal peptide of the immunoprotein CXCL-10	16
Implications of TRPM3 and TRPM8 for sensory neuron sensitisation	15
Protein transport along the presequence pathway	14
Broadened substrate specificity of bacterial dipeptidyl-peptidase 7 enables release of half of all dipeptide combinations from peptide N-termini	14
Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase	14
Frontmatter	13
Highlights in biochemistry Bochum 2022	13
Influence of inflammatory processes on thalamocortical activity	13
Frontmatter	13

Unpaired cysteine insertions favor transmembrane dimerization and induce ligand-independent constitutive cytokine receptor signaling	12
Highlight: structure and function of the peroxisomal translocon	12
A tailored cytochrome P450 monooxygenase from Gordonia rubripertincta CWB2 for selective aliphatic monooxygenation	12
Molecular determinants of protein half-life in chloroplasts with focus on the Clp protease system	12
Pathogenic missense variants of CSNK2B associated with Poirier-Bienvenu neurodevelopmental disorder impact differently on CK2 holoenzyme formation	12
Simultaneous spectral illumination of microplates for high-throughput optogenetics and photobiology	11
Detection of a 7SL RNA-derived small non-coding RNA using Molecular Beacons in vitro and in cells	11
The nascent polypeptide-associated complex (NAC) as regulatory hub on ribosomes	11
Dynamics of the translocation pore of the human peroxisomal protein import machinery	11
Structure and phase separation of the C-terminal domain of RNA polymerase II	11
Frontmatter	11
Comparative studies of soluble and immobilized Fe(III) heme-peptide complexes as alternative heterogeneous biocatalysts	11
Methionine restriction attenuates the migration and invasion of gastric cancer cells by inhibiting nuclear p65 translocation through TRIM47	11
Apolipoprotein E-containing lipoproteins and their extracellular interactions with LRP1 affect LPS-induced inflammation	11
The role of the Na⁺/Ca²⁺-exchanger (NCX) in cancer-associated fibroblasts	10
Inhibition of miR-143-3p alleviates myocardial ischemia reperfusion injury via limiting mitochondria-mediated apoptosis	10
Sarcomere analysis in human cardiomyocytes by computing radial frequency spectra	10
The Zika virus infection remodels the expression of the synaptotagmin-9 secretory protein	10
Actin scaffolds as organizers of presynaptic function, assembly and plasticity across species	10
Protein kinase CK2 contributes to glucose homeostasis	10
Microtubules as a signal hub for axon growth in response to mechanical force	9
The emerging role of ATP as a cosolute for biomolecular processes	9
In vitro ADME characterization of a very potent 3-acylamino-2-aminopropionic acid-derived GluN2C-NMDA receptor agonist and its ester prodrugs	9
Highlight: new developments in immunoengineering	9
The heart of the matter: a personal view of Fred Wittinghofer’s contributions to RAS biology and drug design	9
Conserved function, divergent evolution: mitochondrial outer membrane insertases across eukaryotes	9
Frontmatter	9
Glue it together: self-assembly of the antibacterial GTPase GBP1	9
Frontmatter	9
Unfolded protein responses in Chlamydomonas reinhardtii	9
KCTD5 regulates Ikaros degradation induced by chemotherapeutic drug etoposide in hematological cells	9
Insights in caveolae protein structure arrangements and their local lipid environment	9
Frontmatter	9
Molecular simulations of DEAH-box helicases reveal control of domain flexibility by ligands: RNA, ATP, ADP, and G-patch proteins	8
Extracellular hemin is a reverse use-dependent gating modifier of cardiac voltage-gated Na⁺ channels	8
Extracellular stimulation of lung fibroblasts with arachidonic acid increases interleukin 11 expression through p38 and ERK signaling	8
The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase	8
Membrane binding and pore forming insertion of PEX5 into horizontal lipid bilayer	8
Small-molecule metabolites in SARS-CoV-2 treatment: a comprehensive review	8
Interaction of RTX toxins with the host cell plasma membrane	8
GAP mimetic activity of pan-Ras TCI daraxonrasib synergizes with K-Ras Switch-II pocket inhibition	8
Distinct conformational and energetic features define the specific recognition of (di)aromatic peptide motifs by PEX14	8
Highlight: how to synthesize, assemble and regulate ribonucleoprotein-complexes	8
Rodent models for mood disorders – understanding molecular changes by investigating social behavior	8
Pathological and physiological roles of ADP-ribosylation: established functions and new insights	8
Study of two glycosyltransferases related to polysaccharide biosynthesis in Rhodococcus jostii RHA1	7
The evolution and diversification of the Hsp90 co-chaperone system	7
NF90/NFAR (nuclear factors associated with dsRNA) – a new methylation substrate of the PRMT5-WD45-RioK1 complex	7
Endocytic scaffolds at the crossroads of Alzheimer’s disease and neuronal aging	7
On the structure and function of granzymes, the deadly squad of cytotoxic lymphocytes	7

Modulation of self-organizing circuits at deforming membranes by intracellular and extracellular factors	7
Analysis of cell cycle stage, replicated DNA, and chromatin-associated proteins using high-throughput flow cytometry	7
CK2 control of human papillomavirus life cycles	7
Protein persulfidation in plants: mechanisms and functions beyond a simple stress response	7
Highlight: on the past and the future of cellular microcompartments	7
Cell-type specific anti-cancerous effects of nitro-oleic acid and its combination with gamma irradiation	7
Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features	6
MicroRNA-6838-5p suppresses the self-renewal and metastasis of human liver cancer stem cells through downregulating CBX4 expression and inactivating ERK signaling	6
The mitochondrial intermembrane space – a permanently proteostasis-challenged compartment	6
Cysteine cathepsin proteases in apicomplexan parasites	6
The second PI(3,5)P₂ binding site in the S0 helix of KCNQ1 stabilizes PIP₂-at the primary PI1 site with potential consequences on intermediate-to-open state transit	6
Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2	6
The 76th Mosbacher Colloquium: AI-driven (r)evolution in structural biology and protein design	6
The promise of genetic screens in human in vitro brain models	6
Frontmatter	6
Interaction of nucleoporins with nuclear transport receptors: a structural perspective	6
Celastrol inhibits angiogenesis and the biological processes of MDA-MB-231 cells via the DEGS1/S1P signaling pathway	5
Illuminating the brain-genetically encoded single wavelength fluorescent biosensors to unravel neurotransmitter dynamics	5
Investigation of the P1′ and P2′ sites of IQF substrates and their selectivity toward 20S proteasome subunits	5
M2 macrophages-derived exosomal miR-3917 promotes the progression of lung cancer via targeting GRK6	5
Structure and function of spliceosomal DEAH-box ATPases	5
A CK2α′ mutant indicating why CK2α and CK2α′, the isoforms of the catalytic subunit of human protein kinase CK2, deviate in affinity to CK2β	5
Getting to the right place at the right time – membrane trafficking and maturation in the endolysosomal system	5
LINC00858 facilitates formation of hepatic metastases from colorectal cancer via regulating the miR-132-3p/IGF2BP1 axis	5
The many faces of ribosome translocation along the mRNA: reading frame maintenance, ribosome frameshifting and translational bypassing	5
Fred Wittinghofer and the GTP/GDP-binding proteins	5
Frontmatter	5
Cathepsin L-mediated EGFR cleavage affects intracellular signalling pathways in cancer	5
Frontmatter	5
Interactions of Na⁺/taurocholate cotransporting polypeptide with host cellular proteins upon hepatitis B and D virus infection: novel potential targets for antiviral therapy	5
The role of PDE6D in trafficking KRAS	5
Highlight: chemical biology of ion channels	5
Autophagic and non-autophagic functions of the Saccharomyces cerevisiae PROPPINs Atg18, Atg21 and Hsv2	4
Mycobacterial type VII secretion systems	4
New lipophilic organic nitrates: candidates for chronic skin disease therapy	4
Frontmatter	4
Molecular insights into endolysosomal microcompartment formation and maintenance	4
Unclogging of the TOM complex under import stress	4
Inhibition of Chk1 stimulates cytotoxic action of platinum-based drugs and TRAIL combination in human prostate cancer cells	4
Intersectins as versatile scaffolds for membrane-associated processes	4
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis	4
Heme delivery to heme oxygenase-2 involves glyceraldehyde-3-phosphate dehydrogenase	4
Biochemical evidence for conformational variants in the anti-viral and pro-metastatic protein IFITM1	4
Synthesis of the ribosomal RNA precursor in human cells: mechanisms, factors and regulation	4
Neprilysin 4: an essential peptidase with multifaceted physiological relevance	4
Frontmatter	4
Adherens junctions balance stability and motility: from cell morphogenesis to neural tissue patterning	4
Frontmatter	4
Features of yeast RNA polymerase I with special consideration of the lobe binding subunits	4
Nanoscale organization of Ca_V2.1 splice isoforms at presynaptic terminals: implications for synaptic vesicle release and synaptic facilitation	3
Posttranslational modifications of RAS: few pockets but many bumps	3
Microwave characterization of aqueous amino acid solutions using the multifrequency WGM resonator technique	3
The Rauischholzhausen Transport Colloquium: membrane proteins from structure to function	3
Felix Hoppe-Seyler (1825–1895): a pioneer in the field of biochemistry with many significant contributions to the development of the discipline	3
Good things come to those who bait: the peroxisomal docking complex	3
The DEAD-box RNA helicase Dbp5 is a key protein that couples multiple steps in gene expression	3
The human long non-coding RNA LINC00941 and its modes of action in health and disease	3
Stress response pathways: machineries and mechanisms	3
Frontmatter	3
GPI-anchored serine proteases: essential roles in development, homeostasis, and disease	3
Heme research – the past, the present and the future	3
A primer on heme biosynthesis	3
Frontmatter	3
The proteostasis burden of aneuploidy	3
Time- and dose-dependent effects of CIGB-300 on the proteome of lung squamous cell carcinoma	3
The good or the bad: an overview of autoantibodies in traumatic spinal cord injury	3
Structure, function, and recombinant production of EGFL7	3
Nitazoxanide inhibits osteosarcoma cells growth and metastasis by suppressing AKT/mTOR and Wnt/β-catenin signaling pathways	3
Mechanistic insights on spatiotemporal control of Ras-signaling	3