Biological Chemistry

Article	Citations
Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation and probing NOX4 interactions via molecular docking	57
Frontmatter	40
LncRNA-p21 suppresses cell proliferation and induces apoptosis in gastric cancer by sponging miR-514b-3p and up-regulating ARHGEF9 expression	34
Frontmatter	31
Frontmatter	31
Astrocytic potassium and calcium channels as integrators of the inflammatory and ischemic CNS microenvironment	30
Yme2, a putative RNA recognition motif and AAA+ domain containing protein, genetically interacts with the mitochondrial protein export machinery	27
Highlight: young research groups in Germany – 5th edition	26
Infection, inflammation and thrombosis: a review of potential mechanisms mediating arterial thrombosis associated with influenza and severe acute respiratory syndrome coronavirus 2	26
Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation	24
SRPK1 promotes cell proliferation and tumor growth of osteosarcoma through activation of the NF-κB signaling pathway	21
Characterization of the scavenger cell proteome in mouse and rat liver	20
Synthesis and biological characterization of a new fluorescent probe for vesicular trafficking based on polyazamacrocycle derivative	20
Altered population activity and local tuning heterogeneity in auditory cortex of Cacna2d3-deficient mice	18
Anti-inflammatory dihydroxanthones from a Diaporthe species	17
Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity	16
Diselenide-derivative of 3-pyridinol targets redox enzymes leading to cell cycle deregulation and apoptosis in A549 cells	16
Development of an enabling platform biotechnology for the production of proteins	15
Exceptionally versatile take II: post-translational modifications of lysine and their impact on bacterial physiology	15
Molecular determinants of health and disease	14
Computational resolution in single molecule localization – impact of noise level and emitter density	14
Functional characterisation of two receptor interaction determinants in human thymic stromal lymphopoietin	14
Mechanism of hypoxia-induced exosome circ_0051799 regulating the progression of lung adenocarcinoma	14
Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase	14
Protein transport along the presequence pathway	13

The Mycobacterium tuberculosis prolyl dipeptidyl peptidase cleaves the N-terminal peptide of the immunoprotein CXCL-10	13
Implications of TRPM3 and TRPM8 for sensory neuron sensitisation	13
Influence of inflammatory processes on thalamocortical activity	13
Frontmatter	13
Broadened substrate specificity of bacterial dipeptidyl-peptidase 7 enables release of half of all dipeptide combinations from peptide N-termini	13
The cAMP responsive element modulator (CREM) is a regulator of CD4+ T cell function	12
Unpaired cysteine insertions favor transmembrane dimerization and induce ligand-independent constitutive cytokine receptor signaling	12
Molecular determinants of protein half-life in chloroplasts with focus on the Clp protease system	12
Highlight: structure and function of the peroxisomal translocon	12
Simultaneous spectral illumination of microplates for high-throughput optogenetics and photobiology	12
Dynamics of the translocation pore of the human peroxisomal protein import machinery	11
Frontmatter	11
Comparative studies of soluble and immobilized Fe(III) heme-peptide complexes as alternative heterogeneous biocatalysts	11
Highlights in biochemistry Bochum 2022	11
Characterization of hepatic zonation in mice by mass-spectrometric and antibody-based proteomics approaches	11
Machine learning based disease prediction from genotype data	11
Chemically modified glycosaminoglycan derivatives as building blocks for biomaterial coatings and hydrogels	11
Methionine restriction attenuates the migration and invasion of gastric cancer cells by inhibiting nuclear p65 translocation through TRIM47	10
Detection of a 7SL RNA-derived small non-coding RNA using Molecular Beacons in vitro and in cells	10
Structure and phase separation of the C-terminal domain of RNA polymerase II	10
A tailored cytochrome P450 monooxygenase from Gordonia rubripertincta CWB2 for selective aliphatic monooxygenation	10
Decreased level of miR-1301 promotes colorectal cancer progression via activation of STAT3 pathway	10
Protein engineering & design: hitting new heights	10
Frontmatter	10
Apolipoprotein E-containing lipoproteins and their extracellular interactions with LRP1 affect LPS-induced inflammation	10
Protein kinase CK2 contributes to glucose homeostasis	9
Dynamic phospho-modification of viral proteins as a crucial regulatory layer of influenza A virus replication and innate immune responses	9
The phytochemical plumbagin reciprocally modulates osteoblasts and osteoclasts	9
Structures and nucleic acid-binding preferences of the eukaryotic ARID domain	9
Role of the gut microbiota in airway immunity and host defense against respiratory infections	9
Functional genomics meta-analysis to identify gene set enrichment networks in cardiac hypertrophy	9
The nascent polypeptide-associated complex (NAC) as regulatory hub on ribosomes	9
Structural insights into the repair mechanism of AGT for methyl-induced DNA damage	8
The role of ADAM17 during liver damage	8
Inhibition of miR-143-3p alleviates myocardial ischemia reperfusion injury via limiting mitochondria-mediated apoptosis	8
Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins	8
KCTD5 regulates Ikaros degradation induced by chemotherapeutic drug etoposide in hematological cells	8
In vitro ADME characterization of a very potent 3-acylamino-2-aminopropionic acid-derived GluN2C-NMDA receptor agonist and its ester prodrugs	8
The emerging role of ATP as a cosolute for biomolecular processes	8
The role of the Na+/Ca2+-exchanger (NCX) in cancer-associated fibroblasts	8
Insights in caveolae protein structure arrangements and their local lipid environment	8
Highlight: new developments in immunoengineering	8
Tumor cell lysis and synergistically enhanced antibody-dependent cell-mediated cytotoxicity by NKG2D engagement with a bispecific immunoligand targeting the HER2 antigen	8
The Zika virus infection remodels the expression of the synaptotagmin-9 secretory protein	8
Frontmatter	7
Frontmatter	7
A liquid-culture-based screening approach to study compounds affecting inflammatory processes in Caenorhabditis elegans	7
Improvement of wound healing by the development of ECM-inspired biomaterial coatings and controlled protein release	7
Eukaryotic tRNA splicing – one goal, two strategies, many players	7
Microtubules as a signal hub for axon growth in response to mechanical force	7

Structural basis of Alzheimer β-amyloid peptide recognition by engineered lipocalin proteins with aggregation-blocking activity	7
Frontmatter	7
Unfolded protein responses in Chlamydomonas reinhardtii	7
Bioinformatics in theory and application – highlights of the 36th German Conference on Bioinformatics	6
Frontmatter	6
Post-translational lysine ac(et)ylation in health, ageing and disease	6
Unification of functional annotation descriptions using text mining	6
Extracellular hemin is a reverse use-dependent gating modifier of cardiac voltage-gated Na+ channels	6
A guide to designing photocontrol in proteins: methods, strategies and applications	6
Molecular simulations of DEAH-box helicases reveal control of domain flexibility by ligands: RNA, ATP, ADP, and G-patch proteins	6
Extracellular stimulation of lung fibroblasts with arachidonic acid increases interleukin 11 expression through p38 and ERK signaling	6
Highlight: how to synthesize, assemble and regulate ribonucleoprotein-complexes	6
Membrane binding and pore forming insertion of PEX5 into horizontal lipid bilayer	6
Frontmatter	6
The paracaspase MALT1 in psoriasis	6
Frontmatter	6
The relevance of adhesion G protein-coupled receptors in metabolic functions	6
Interaction of RTX toxins with the host cell plasma membrane	6
Distinct conformational and energetic features define the specific recognition of (di)aromatic peptide motifs by PEX14	6
Small-molecule metabolites in SARS-CoV-2 treatment: a comprehensive review	6
Epitranscriptomic modifications in acute myeloid leukemia: m6A and 2′-O-methylation as targets for novel therapeutic strategies	5
The antioxidant Rutin counteracts the pathological impact of α-synuclein on the enteric nervous system in vitro	5
Pathological and physiological roles of ADP-ribosylation: established functions and new insights	5
Atomistic insight into the essential binding event of ACE2-derived peptides to the SARS-CoV-2 spike protein	5
Cell-type specific anti-cancerous effects of nitro-oleic acid and its combination with gamma irradiation	5
The evolution and diversification of the Hsp90 co-chaperone system	5
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transit	5
Study of two glycosyltransferases related to polysaccharide biosynthesis in Rhodococcus jostii RHA1	5
Application of RtcB ligase to monitor self-cleaving ribozyme activity by RNA-seq	5
Effect of myeloperoxidase oxidation and N-homocysteinylation of high-density lipoprotein on endothelial repair function	5
Rodent models for mood disorders – understanding molecular changes by investigating social behavior	5
Pathomechanisms in hepatic encephalopathy	5
Collagen/glycosaminoglycan-based matrices for controlling skin cell responses	5
Berberine improves dietary-induced cardiac remodeling by upregulating Kruppel-like factor 4-dependent mitochondrial function	5
Modulation of self-organizing circuits at deforming membranes by intracellular and extracellular factors	5
Analysis of cell cycle stage, replicated DNA, and chromatin-associated proteins using high-throughput flow cytometry	5
Long non-coding RNA FAM66C regulates glioma growth via the miRNA/LATS1 signaling pathway	5
The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase	5
Signal transduction in health and disease	5
Chemerin – exploring a versatile adipokine	5
Insights into structure, affinity, specificity, and function of GAG-protein interactions through the chemoenzymatic preparation of defined sulfated oligohyaluronans	5
Protein persulfidation in plants: mechanisms and functions beyond a simple stress response	5
Highlight: on the past and the future of cellular microcompartments	5
Lymphotoxin-β-receptor (LTβR) signaling on hepatocytes is required for liver regeneration after partial hepatectomy	5
Two-photon fluorescent turn-on probes for highly efficient detection and profiling of thiols in live cells and tissues	4
Frontmatter	4
Transfer RNA processing – from a structural and disease perspective	4
Frontmatter	4
NF90/NFAR (nuclear factors associated with dsRNA) – a new methylation substrate of the PRMT5-WD45-RioK1 complex	4
Corrigendum to: Emerging mechanisms of drug-induced phospholipidosis	4
Cathepsin L-mediated EGFR cleavage affects intracellular signalling pathways in cancer	4
Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2	4
Interactions of Na+/taurocholate cotransporting polypeptide with host cellular proteins upon hepatitis B and D virus infection: novel potential targets for antiviral therapy	4
Expanded profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39	4
LINC00858 facilitates formation of hepatic metastases from colorectal cancer via regulating the miR-132-3p/IGF2BP1 axis	4
Illuminating the brain-genetically encoded single wavelength fluorescent biosensors to unravel neurotransmitter dynamics	4
MicroRNA-6838-5p suppresses the self-renewal and metastasis of human liver cancer stem cells through downregulating CBX4 expression and inactivating ERK signaling	4
The promise of genetic screens in human in vitro brain models	4
Interaction of nucleoporins with nuclear transport receptors: a structural perspective	4
Celastrol inhibits angiogenesis and the biological processes of MDA-MB-231 cells via the DEGS1/S1P signaling pathway	4
Mycobacterial type VII secretion systems	4
The many faces of ribosome translocation along the mRNA: reading frame maintenance, ribosome frameshifting and translational bypassing	4
M2 macrophages-derived exosomal miR-3917 promotes the progression of lung cancer via targeting GRK6	4
Investigation of the P1′ and P2′ sites of IQF substrates and their selectivity toward 20S proteasome subunits	4
Men who stare at bone: multimodal monitoring of bone healing	4
Frontmatter	4
Frontmatter	4
Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies	4
Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features	4
Inhibition of Chk1 stimulates cytotoxic action of platinum-based drugs and TRAIL combination in human prostate cancer cells	4
Frontmatter	4
Structure and function of spliceosomal DEAH-box ATPases	4
Frontmatter	3
Biochemical evidence for conformational variants in the anti-viral and pro-metastatic protein IFITM1	3
Molecular insights into endolysosomal microcompartment formation and maintenance	3
Fibrillar biopolymer-based scaffolds to study macrophage-fibroblast crosstalk in wound repair	3
Controllers of cutaneous regulatory T cells: ultraviolet radiation and the skin microbiome	3
Frontmatter	3
Starting the engine of the powerhouse: mitochondrial transcription and beyond	3
Frontmatter	3

Heme delivery to heme oxygenase-2 involves glyceraldehyde-3-phosphate dehydrogenase	3
Synthesis of the ribosomal RNA precursor in human cells: mechanisms, factors and regulation	3
Drug development for neurodegenerative diseases	3
A CK2α′ mutant indicating why CK2α and CK2α′, the isoforms of the catalytic subunit of human protein kinase CK2, deviate in affinity to CK2β	3
Neprilysin 4: an essential peptidase with multifaceted physiological relevance	3
Tissue factor pathway inhibitor 2 is a potent kallikrein-related protease 12 inhibitor	3
Autophagic and non-autophagic functions of the Saccharomyces cerevisiae PROPPINs Atg18, Atg21 and Hsv2	3
Features of yeast RNA polymerase I with special consideration of the lobe binding subunits	3
Unclogging of the TOM complex under import stress	3
New lipophilic organic nitrates: candidates for chronic skin disease therapy	3
Hepatic stellate cells: current state and open questions	3
Highlight: chemical biology of ion channels	3
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis	3
The mitochondrial unfolded protein response: acting near and far	2
GPI-anchored serine proteases: essential roles in development, homeostasis, and disease	2
Molecular determinants of therapy response of venetoclax-based combinations in acute myeloid leukemia	2
Heme research – the past, the present and the future	2
Frontmatter	2
Epithelial-mesenchymal transition and H2O2 signaling – a driver of disease progression and a vulnerability in cancers	2
Frontmatter	2
Trispecific antibodies produced from mAb2 pairs by controlled Fab-arm exchange	2
Structural insights into the modulation of PDGF/PDGFR-β complexation by hyaluronan derivatives	2
Glutamine synthetase as a central element in hepatic glutamine and ammonia metabolism: novel aspects	2
Frontmatter	2
Rational approaches towards inorganic and organometallic antibacterials	2
Frontmatter	2
Frontmatter	2
Microwave characterization of aqueous amino acid solutions using the multifrequency WGM resonator technique	2
The role of mycotoxins in neurodegenerative diseases: current state of the art and future perspectives of research	2
A primer on heme biosynthesis	2
The human long non-coding RNA LINC00941 and its modes of action in health and disease	2
The proteostasis burden of aneuploidy	2
Schwann cells in neuromuscular in vitro models	2
The extracellular region of bovine milk butyrophilin exhibits closer structural similarity to human myelin oligodendrocyte glycoprotein than to immunological BTN family receptors	2
Structure, function, and recombinant production of EGFL7	2
The DEAD-box RNA helicase Dbp5 is a key protein that couples multiple steps in gene expression	2
The good or the bad: an overview of autoantibodies in traumatic spinal cord injury	2
Nitazoxanide inhibits osteosarcoma cells growth and metastasis by suppressing AKT/mTOR and Wnt/β-catenin signaling pathways	2
Highlight: Young research groups in Germany – 4th edition	2
Time- and dose-dependent effects of CIGB-300 on the proteome of lung squamous cell carcinoma	2
Advances in preclinical TCR characterization: leveraging cell avidity to identify functional TCRs	2
Good things come to those who bait: the peroxisomal docking complex	2
Nanoscale organization of CaV2.1 splice isoforms at presynaptic terminals: implications for synaptic vesicle release and synaptic facilitation	2
Frontmatter	2
The Rauischholzhausen Transport Colloquium: membrane proteins from structure to function	2