OOIR: Observatory of International Research

Papers

(The H4-Index of International Journal of Molecular Sciences is 137. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Modeling SILAC Data to Assess Protein Turnover in a Cellular Model of Diabetic Nephropathy	1175
Natural Killer Cells and Their Implications in Immune Response Diversification in Clinical Pathology and Neoplastic Processes	919
Gamma-Hemolysin Components: Computational Strategies for LukF-Hlg2 Dimer Reconstruction on a Model Membrane	843
Simple Coumarins from Peucedanum luxurians Fruits: Evaluation of Anxiolytic Activity and Influence on Gene Expression Related to Anxiety in Zebrafish Model	826
ZIM1 Combined with Hydrogel Inhibits Senescence of Primary PαS Cells during In Vitro Expansion	792
Comprehensive Analysis of the Role of Gene Variants in Matrix Metalloproteinases and Their Tissue Inhibitors in Retinopathy of Prematurity: A Study in the Polish Population	642
Overexpression of Lolium multiflorum LmMYB1 Enhances Drought Tolerance in Transgenic Arabidopsis	563
Involvement of Dynamic Adjustment of ABA, Proline and Sugar Levels in Rhizomes in Effective Acclimation of Solidago gigantea to Contrasting Weather and Soil Conditions in the Country of Invasion	526
Vaping-Induced Proteolysis Causes Airway Surface Dehydration	505
Cancer 3D Models for Metallodrug Preclinical Testing	449
Genetic Incorporation of Dansylalanine in Human Ferroportin to Probe the Alternating Access Mechanism of Iron Transport	427
Tricellulin, α-Catenin and Microfibrillar-Associated Protein 5 Exhibit Concomitantly Altered Immunosignals along with Vascular, Extracellular and Cytoskeletal Elements after Experimental Focal Cerebra	411
Understanding the Exchange Interaction between Paramagnetic Metal Ions and Radical Ligands: DFT and Ab Initio Study on Semiquinonato Cu(II) Complexes	395
Neuromodulators as Interdomain Signaling Molecules Capable of Occupying Effector Binding Sites in Bacterial Transcription Factors	375
Genome-Wide Identification of the Soybean LysM-RLK Family Genes and Its Nitrogen Response	373
Competitive Chemical Reaction Kinetic Model of Nucleosome Assembly Using the Histone Variant H2A.Z and H2A In Vitro	371
A Single Nucleotide Variation of CRS2 Affected the Establishment of Photosynthetic System in Rice	365
Assessment of Tissue Expression of the Oxytocin–Vasopressin Pathway in the Placenta of Women with a First-Episode Psychosis during Pregnancy	327
Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NFκB and Mitochondrial Pathways	322
Unveiling the Role of Endothelial Dysfunction: A Possible Key to Enhancing Catheter Ablation Success in Atrial Fibrillation	300
The Involvement of Cysteine-X-Cysteine Motif Chemokine Receptors in Skin Homeostasis and the Pathogenesis of Allergic Contact Dermatitis and Psoriasis	294
Nicotinic Receptors in Human Chromaffin Cells: Characterization, Functional and Physical Interactions between Subtypes and Regulation	292
Nanostructured Coatings Based on Graphene Oxide for the Management of Periprosthetic Infections	287
The Model of Interstitial Cystitis for Evaluating New Molecular Strategies of Interstitial Regeneration in Humans	280
SUMOylation Inhibition Enhances Protein Transcription under CMV Promoter: A Lesson from a Study with the F508del-CFTR Mutant	276

The Molecular Mechanism of Body Axis Induction in Lampreys May Differ from That in Amphibians	275
Identification of Molecular Mechanisms in Radiation Cystitis: Insights from RNA Sequencing	274
A Dinuclear Copper(II) Complex Electrochemically Obtained via the Endogenous Hydroxylation of a Carbamate Schiff Base Ligand: Synthesis, Structure and Catalase Activity	274
TRP Ion Channels in Immune Cells and Their Implications for Inflammation	267
Roles of lncRNAs in NF-κB-Mediated Macrophage Inflammation and Their Implications in the Pathogenesis of Human Diseases	267
Lipidomics Reveals Myocardial Lipid Composition in a Murine Model of Insulin Resistance Induced by a High-Fat Diet	263
Drought Stress Induced Different Response Mechanisms in Three Dendrobium Species under Different Photosynthetic Pathways	259
Hypothermia Inhibits Dexmedetomidine-Induced Contractions in Isolated Rat Aortae	258
Structural Characterization of Several Cement-Based Materials Containing Chemical Additives with Potential Application in Additive Manufacturing	256
Current Medical Therapy and Revascularization in Peripheral Artery Disease of the Lower Limbs: Impacts on Subclinical Chronic Inflammation	253
Predicting the Structure of Enzymes with Metal Cofactors: The Example of [FeFe] Hydrogenases	250
Regulation Mechanism and Potential Value of Active Substances in Spices in Alcohol–Liver–Intestine Axis Health	246
Ancistrocladus tectorius Extract Inhibits Obesity by Promoting Thermogenesis and Mitochondrial Dynamics in High-Fat Diet-Fed Mice	246
Gene Expression Patterns Associated with Survival in Glioblastoma	246
Substance P Concentration in Gestational Diabetes and Excessive Gestational Weight Gain and Its Impact on Neonatal Anthropometry	240
Anti-Inflammatory Effects of a Novel Acetonitrile–Water Extract of Lens Culinaris against LPS-Induced Damage in Caco-2 Cells	239
Immunomodulation through Nutrition Should Be a Key Trend in Type 2 Diabetes Treatment	236
Can T Cells Abort SARS-CoV-2 and Other Viral Infections?	234
Targeting Interleukin-13 Receptor α2 and EphA2 in Aggressive Breast Cancer Subtypes with Special References to Chimeric Antigen Receptor T-Cell Therapy	234
Mapping of Prion Structures in the Yeast Rnq1	232
Autumn Olive (Elaeagnus umbellata Thunb.) Berries Improve Lipid Metabolism and Delay Aging in Middle-Aged Caenorhabditis elegans	229
Genome-Wide Identification of the 14-3-3 Gene Family and Its Involvement in Salt Stress Response through Interaction with NsVP1 in Nitraria sibirica Pall	226
Preparation and Activity of Hemostatic and Antibacterial Dressings with Greige Cotton/Zeolite Formularies Having Silver and Ascorbic Acid Finishes	225
The Impact of Hypromellose on Pharmaceutical Properties of Alginate Microparticles as Novel Drug Carriers for Posaconazole	225
Structural Analysis of Breast-Milk αS1-Casein: An α-Helical Conformation Is Required for TLR4-Stimulation	217
Application of Simultaneous and Coupled Thermal Analysis Techniques in Studies on the Melting Process, Course of Pyrolysis and Oxidative Decomposition of Fused Triazinylacetohydrazides	217
Bioinformatics Insights on Viral Gene Expression Transactivation: From HIV-1 to SARS-CoV-2	215
A Water-Based Biocoating to Increase the Infection Resistance and Osteoconductivity of Titanium Surfaces	214
Genome-Wide Identification of PEBP Gene Family in Two Dendrobium Species and Expression Patterns in Dendrobium chrysotoxum	212
Detergent-Mediated Virus Inactivation in Biotechnological Matrices: More than Just CMC	212
Insights into the Mechanism of Action of the Degraded Limonoid Prieurianin	211
Biochemical Fractionation of Human α-Synuclein in a Drosophila Model of Synucleinopathies	208
The MDM2–p53 Axis Represents a Therapeutic Vulnerability Unique to Glioma Stem Cells	204
Implementing a New Algorithm for Reinterpretation of Ambiguous Variants in Genetic Dilated Cardiomyopathy	202
Rituximab, Intravitreal Bevacizumab and Laser Photocoagulation for Treatment of Macrophage Activation Syndrome and Retinal Vasculitis in Lupus: A Case Report	199
A Novel Mechanically Robust and Biodegradable Egg White Hydrogel Membrane by Combined Unidirectional Nanopore Dehydration and Annealing	199
Study of Processing Conditions during Enzymatic Hydrolysis of Deer By-Product Tallow for Targeted Changes at the Molecular Level and Properties of Modified Fats	197
Incorporating Monoclonal Antibodies into the First-Line Treatment of Classical Hodgkin Lymphoma	195
Undifferentiated Carcinoma with Osteoclast-like Giant Cells of the Pancreas: Molecular Genetic Analysis of 13 Cases	195
High-Loaded Copper-Containing Sol–Gel Catalysts for Furfural Hydroconversion	194
Molecular Mechanism in the Development of Pulmonary Fibrosis in Patients with Sarcoidosis	192
Phytocannabinoids Reduce Inflammation of Primed Macrophages and Enteric Glial Cells: An In Vitro Study	185
Identification and Validation of Quantitative Trait Loci Mapping for Spike-Layer Uniformity in Wheat	184
Short Sequence Aligner Benchmarking for Chromatin Research	182
Spontaneous Fusion of MSC with Breast Cancer Cells Can Generate Tumor Dormancy	180
Correlation of Albumin, Red Cell Distribution Width and Other Biochemical and Hematological Parameters with Glycated Hemoglobin in Diabetic, Prediabetic and Non-Diabetic Patients	179
Production and Biochemical Characterization of Dimeric Recombinant Gremlin-1	178
Vypal2: A Versatile Peptide Ligase for Precision Tailoring of Proteins	177
Radical Scavenging Activity and Pharmacokinetic Properties of Coumarin–Hydroxybenzohydrazide Hybrids	177
Identification and Determination of 1,3-Thiazinane-4-carboxylic Acid in Human Urine—Chromatographic Studies	176

Discovery of microRNA-like Small RNAs in Pathogenic Plant Fungus Verticillium nonalfalfae Using High-Throughput Sequencing and qPCR and RLM-RACE Validation	176
A New RING Finger Protein, PLANT ARCHITECTURE and GRAIN NUMBER 1, Affects Plant Architecture and Grain Yield in Rice	175
Translational Study of Copy Number Variations in Schizophrenia	174
Genome-Wide Association Study Identifies Candidate Genes Related to the Linoleic Acid Content in Soybean Seeds	172
Specific Mutations in Aph1 Cause γ-Secretase Activation	169
Two-Dimensional Interfacial Exchange Diffusion Has the Potential to Augment Spatiotemporal Precision of Ca2+ Signaling	169
Disease Outcome and Brain Metabolomics of Cyclophilin-D Knockout Mice in Sepsis	168
Abiotic Stresses in Plants: From Molecules to Environment	168
Identifying Candidate Protein Markers of Acute Kidney Injury in Acute Decompensated Heart Failure	168
Placenta-Specific miR-125b Overexpression Leads to Increased Rates of Pregnancy Loss in Mice	166
Upregulated Nuclear Expression of Soluble Epoxide Hydrolase Predicts Poor Outcome in Breast Cancer Patients: Importance of the Digital Pathology Approach	166
Theranostic Platforms Based on Silica and Magnetic Nanoparticles Containing Quinacrine, Chitosan, Fluorophores, and Quantum Dots	165
GPR55 Antagonist CID16020046 Protects against Atherosclerosis Development in Mice by Inhibiting Monocyte Adhesion and Mac-1 Expression	164
Early Intervention of Cold-Water Swimming on Functional Recovery and Spinal Pain Modulation Following Brachial Plexus Avulsion in Rats	164
Elevated Arterial Blood Pressure as a Delayed Complication Following COVID-19—A Narrative Review	164
IDO and CD40 May Be Key Molecules for Immunomodulatory Capacity of the Primed Tonsil-Derived Mesenchymal Stem Cells	163
Long RNA-Mediated Chromatin Regulation in Fission Yeast and Mammals	161
Novel Loss of Function Variant in BCKDK Causes a Treatable Developmental and Epileptic Encephalopathy	161
Sequence Does Not Matter: The Biomedical Applications of DNA-Based Coatings and Cores	161
Intrinsic Expression of Coagulation Factors and Protease Activated Receptor 1 (PAR1) in Photoreceptors and Inner Retinal Layers	161
Porous Biphasic Calcium Phosphate Granules from Oyster Shell Promote the Differentiation of Induced Pluripotent Stem Cells	159
Lectin-Mediated Bacterial Modulation by the Intestinal Nematode Ascaris suum	159
When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases	158
Phytochemical Study on Seeds of Paeonia clusii subsp. rhodia—Antioxidant and Anti-Tyrosinase Properties	158
The Heparanase Regulatory Network in Health and Disease	157
Vitamin D Status in Patients before Thyroidectomy	157
Application of Molecular Dynamics Simulations to Determine Interactions between Canary Seed (Phalaris canariensis L.) Bioactive Peptides and Skin-Aging Enzymes	157
Cadherin Signaling in Cancer and Autoimmune Diseases	155
Telomere Length in Human Spermatogenic Cells as a New Potential Predictor of Clinical Outcomes in ART Treatment with Intracytoplasmic Injection of Testicular Spermatozoa	154
Picrasidine I Triggers Heme Oxygenase-1-Induced Apoptosis in Nasopharyngeal Carcinoma Cells via ERK and Akt Signaling Pathways	153
Novel 2-(Adamantan-1-ylamino)Thiazol-4(5H)-One Derivatives and Their Inhibitory Activity towards 11β-HSD1—Synthesis, Molecular Docking and In Vitro Studies	152
Characterization of Mono- and Bi-Transgenic Pig-Derived Epidermal Keratinocytes Expressing Human FUT2 and GLA Genes—In Vitro Studies	152
Bioinformatics Analysis of RNA-seq Data Reveals Genes Related to Cancer Stem Cells in Colorectal Cancerogenesis	152
Low Intensity Shockwave Treatment Modulates Macrophage Functions Beneficial to Healing Chronic Wounds	152
Immune Modulation by Myeloid-Derived Suppressor Cells in Diabetic Kidney Disease	151
Acetylation Enhances the Anticancer Activity and Oral Bioavailability of 5-Demethyltangeretin	151
GcvB Regulon Revealed by Transcriptomic and Proteomic Analysis in Vibrio alginolyticus	150
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood–Milk Barrier	150
Age-Associated Loss in Renal Nestin-Positive Progenitor Cells	148
The Expression Pattern of Surface Markers in Canine Adipose-Derived Mesenchymal Stem Cells	148
Expression and Transcript Localization of star, sf-1, and dax-1 in the Early Brain of the Orange-Spotted Grouper Epinephelus coioides	148
Autophagy and Metabolism in Normal and Malignant Hematopoiesis	147
Adjustments of the Phytochemical Profile of Broccoli to Low and High Growing Temperatures: Implications for the Bioactivity of Its Extracts	147
Development and Regeneration of Muscle, Tendon, and Myotendinous Junctions in Striated Skeletal Muscle	146
Order vs. Disorder: Cholesterol and Omega-3 Phospholipids Determine Biomembrane Organization	145
Zygo-Albuside A: New Saponin from Zygophyllum album L. with Significant Antioxidant, Anti-Inflammatory and Antiapoptotic Effects against Methotrexate-Induced Testicular Damage	145
Acute Hypoxia Alters Extracellular Vesicle Signatures and the Brain Citrullinome of Naked Mole-Rats (Heterocephalus glaber)	144
Small Extracellular Vesicles Containing miR-34c Derived from Bone Marrow Mesenchymal Stem Cells Regulates Epithelial Sodium Channel via Targeting MARCKS	144
Mechanochemical Transformations of Polysaccharides: A Systematic Review	144
Rho GTPases in Retinal Vascular Diseases	142
Enhanced Expression of ARK5 in Hepatic Stellate Cell and Hepatocyte Synergistically Promote Liver Fibrosis	140
Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents	140
Oncogenic Viruses and the Epigenome: How Viruses Hijack Epigenetic Mechanisms to Drive Cancer	140
Transcriptomic Analysis in Human 3D Skin Model Injected with Resorbable Hyaluronic Acid Fillers Reveals Foreign Body Response	140
Low-Dose Delta-9-Tetrahydrocannabinol as Beneficial Treatment for Aged APP/PS1 Mice	140
Increase in Cd Tolerance through Seed-Borne Endophytic Fungus Epichloë gansuensis Affected Root Exudates and Rhizosphere Bacterial Community of Achnatherum inebrians	140
Subzero Nonfreezing Hypothermia with Insect Antifreeze Protein Dramatically Improves Survival Rate of Mammalian Cells	140
Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells	140
Serum Progranulin Level Might Differentiate Non-IPF ILD from IPF	139
Theoretical and Experimental Study of Joint Osmotic and Electroosmotic Water Transfer through a Cation-Exchange Membrane	138
Towards a Treatment for Neuroinflammation in Epilepsy: Interleukin-1 Receptor Antagonist, Anakinra, as a Potential Treatment in Intractable Epilepsy	138
Antimicrobial and Photoantimicrobial Activities of Chitosan/CNPPV Nanocomposites	138