International Journal of Molecular Sciences

Article	Citations
Genetic Variation in Wheat Root Transcriptome Responses to Salinity: A Comparative Study of Tolerant and Sensitive Genotypes	1074
Mechanism of Functional Compound Fruit Drinks in Regulating Serum Metabolism in Constipated Mice	777
Study of the Pollen Grain Metabolome under Deposition of Nitrogen and Phosphorus in Taxus baccata L. and Juniperus communis L.	740
Classification of Subgroups with Immune Characteristics Based on DNA Methylation in Luminal Breast Cancer	730
Physiological Impact of a Synthetic Elastic Protein in Arterial Diseases Related to Alterations of Elastic Fibers: Effect on the Aorta of Elastin-Haploinsufficient Male and Female Mice	718
Dimerisation of the Yeast K+ Translocation Protein Trk1 Depends on the K+ Concentration	670
5-Aminolevrinic Acid Exhibits Dual Effects on Stemness in Human Sarcoma Cell Lines under Dark Conditions	610
Macromolecular Structure of Linearly Arranged Eukaryotic Chromosomes	530
Function of Cajal Bodies in Nuclear RNA Retention in A. thaliana Leaves Subjected to Hypoxia	502
PLG-007 and Its Active Component Galactomannan-α Competitively Inhibit Enzymes That Hydrolyze Glucose Polymers	499
Multi-Modal and Molecular Imaging of Cellular Microenvironment and Tissue Development	461
Transcriptome Analysis to Identify Genes Related to Flowering Reversion in Tomato	458
Health-Promoting Properties of Natural Flavonol Glycosides Isolated from Staphylea pinnata L.	443
Strategies for Altering Delivery Technologies to Optimize CAR Therapy	437
Prognostic Significance of B7H3 Expression in Solid Tumors: A Systematic Review and Meta-Analysis	429
Cost-Effective Mechanical Aggregation of Cardiac Progenitors and Encapsulation in Matrigel Support Self-Organization in a Dynamic Culture Environment	421
Molecular Diagnostic and Prognostication Assays for the Subtyping of Urinary Bladder Cancer Are on the Way to Illuminating Our Vision	407
Galactose in the Post-Weaning Diet Programs Improved Circulating Adiponectin Concentrations and Skeletal Muscle Insulin Signaling	406
Cirsium Setidens Water Extracts Containing Linarin Block Estrogen Deprivation-Induced Bone Loss in Mice	405
Investigating the Inhibitory Effects of Paliperidone on RAGEs: Docking, DFT, MD Simulations, MMPBSA, MTT, Apoptosis, and Immunoblotting Studies	393
miR-17-5p-Mediated RNA Activation Upregulates KPNA2 Expression and Inhibits High-Glucose-Induced Apoptosis of Sheep Granulosa Cells	391
Characterization of Novel Plantaricin-Derived Antiviral Peptides Against Flaviviruses	342
PCSK9 Expression in Vascular Smooth Muscle Cells: Role of Insulin Resistance and High Glucose	333
Improving Replication in Endometrial Omics: Understanding the Influence of the Menstrual Cycle	330
Polymeric Polylactic Acid–Glycolic Acid-Based Nanoparticles Deliver Nintedanib Across the Blood–Brain Barrier to Inhibit Glioblastoma Growth	328

Loss of Myostatin Affects m6A Modification but Not Semen Characteristics in Bull Spermatozoa	324
VX-770, Cact-A1, and Increased Intracellular cAMP Have Distinct Acute Impacts upon CFTR Activity	322
Mitochondrial Genome Characteristics Reveal Evolution of Danxiaorchis yangii and Phylogenetic Relationships	322
Novel Assignment of Gene Markers to Hematological and Immune Cells Based on Single-Cell Transcriptomics	318
Novel Aurora A Kinase Inhibitor Fangchinoline Enhances Cisplatin–DNA Adducts and Cisplatin Therapeutic Efficacy in OVCAR-3 Ovarian Cancer Cells-Derived Xenograft Model	317
Single-Nucleotide Polymorphism in Genes Encoding G Protein Subunits GNB3 and GNAQ Increase the Risk of Cardiovascular Morbidity among Patients Undergoing Renal Replacement Therapy	314
Identifying QTLs for Grain Size in a Colossal Grain Rice (Oryza sativa L.) Line, and Analysis of Additive Effects of QTLs	311
Antisense Oligonucleotides Conjugated with Lipophilic Compounds: Synthesis and In Vitro Evaluation of Exon Skipping in Duchenne Muscular Dystrophy	309
A Novel, Cell-Free Therapy to Enter Our Hearts: The Potential Role of Small EVs in Prevention and Treatment of CVD	303
Transcriptional Regulation of Cardiac Development and Disease	297
Development of a Smart Fluorescent Probe Specifically Interacting with C-Myc I-Motif	295
Reactive Oxygen Species and Folate Receptor-Targeted Nanophotosensitizers Composed of Folic Acid-Conjugated and Poly(ethylene glycol)-Chlorin e6 Tetramer Having Diselenide Linkages for Targeted Photod	290
Hyperosmotic Stress Induces Phosphorylation of CERT and Enhances Its Tethering throughout the Endoplasmic Reticulum	288
A Comprehensive Self-Resistance Gene Database for Natural-Product Discovery with an Application to Marine Bacterial Genome Mining	287
Application of Molecular Dynamics Simulations to Determine Interactions between Canary Seed (Phalaris canariensis L.) Bioactive Peptides and Skin-Aging Enzymes	285
Blood Proteome Profiling Reveals Biomarkers and Pathway Alterations in Fragile X PM at Risk for Developing FXTAS	282
Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites	282
Association of Klotho with Coronary Artery Disease in Subjects with Type 2 Diabetes Mellitus and Preserved Kidney Function: A Case-Control Study	281
Cytokine Dynamics in Autism: Analysis of BMAC Therapy Outcomes	279
Molecular and Cellular Insights: A Focus on Glycans and the HNK1 Epitope in Autism Spectrum Disorder	273
Glucokinase Variant Proteins Are Resistant to Fasting-Induced Uridine Diphosphate Glucose-Dependent Degradation in Maturity-Onset Diabetes of the Young Type 2 Patients	271
Investigating the Influence of Morphine and Cocaine on the Mesolimbic Pathway Using a Novel Microimaging Platform	270
Relevance of Phytochemical Taste for Anti-Cancer Activity: A Statistical Inquiry	266
Germline CSF3R Variant in Chronic Myelomonocytic Leukemia: Linking Genetic Predisposition to Uncommon Hemorrhagic Symptoms	265
Untargeted Lipidomics Analysis Unravels the Different Metabolites in the Fat Body of Mated Bumblebee (Bombus terrestris) Queens	264
Starting Editorial of “Cellular Damage: Protection and Induction” Addressing Hot Topics in Cellular Damage, Protection of Cells and Therapy Targeting Bad Cells	264
Associations between Host Genetic Variants and Subgingival Microbiota in Patients with the Metabolic Syndrome	263
Short-Term and Long-Term Effects after Exposure to Ionizing Radiation and Visible Light on Retina and Retinal Pigment Epithelium of Mouse Eye	262
Indenopyrene and Blue-Light Co-Exposure Impairs the Tightly Controlled Activation of Xenobiotic Metabolism in Retinal Pigment Epithelial Cells: A Mechanism for Synergistic Toxicity	262
Ageing-Related Alterations in Renal Epithelial Glucose Transport	261
Alterations in Intratumoral Immune Response before and during Early-On Nivolumab Treatment for Unresectable Advanced or Recurrent Gastric Cancer	260
Novel Molecular Approaches to the Understanding of Pathophysiologal Mechanisms Acting in Human Embryos: An Editorial	258
Singularity and Commonality in Response to SARS-CoV-2 in Lung and Colon Cell Models	256
Chaperone Hsp70 (HSPA1) Is Involved in the Molecular Mechanisms of Sleep Cycle Integration	256
Preliminary Study on the Formation Mechanism of Malformed Sweet Cherry (Prunus avium L.) Fruits in Southern China Using Transcriptome and Metabolome Data	255
Reverse Onco-Cardiology: What Is the Evidence for Breast Cancer? A Systematic Review of the Literature	255
3′dNTP Binding Is Modulated during Primer Synthesis and Translesion by Human PrimPol	253
PET Molecular Imaging: Old Habits Do Not Die, They Only Evolve into New Applications	253
The Local Environment of Loop Switch 1 Modulates the Rate of ATP-Induced Dissociation of Human Cardiac Actomyosin	252
1-Isobutanoil-2-isopropylisothiourea Phosphate, T1082: A Safe and Effective Prevention of Radiotherapy Complications in Oncology	251
Comparison of Macrophage Immune Responses and Metabolic Reprogramming in Smooth and Rough Variant Infections of Mycobacterium mucogenicum	250
Nitroxyl Delivered by Angeli’s Salt Causes Short-Lasting Activation Followed by Long-Lasting Deactivation of Meningeal Afferents in Models of Headache Generation	250
The Finely Coordinated Action of SSB and NurA/HerA Complex Strictly Regulates the DNA End Resection Process in Saccharolobus solfataricus	248
Synthesis and Vibrational Circular Dichroism Analysis of N-Heterocyclic Carbene Precursors Containing Remote Chirality Centers	244
Role of Nuclear Receptors in Controlling Erythropoiesis	244
Metabolic and Transcriptomic Analyses Reveal Different Metabolite Biosynthesis Profiles between Purple and Green Pak Choi	243
Photonics of Some Monomethine Cyanine Dyes in Solutions and in Complexes with Biomolecules	242
Physiological, Proteomic, and Resin Yield-Related Genes Expression Analysis Provides Insights into the Mechanisms Regulating Resin Yield in Masson Pine	242
Dynamic Properties of Di(cyclopentadienecarboxylic Acid) Dimethyl Esters	241
Current Trends of Bacterial and Fungal Optoproteins for Novel Optical Applications	237

The Biostimulant, Potassium Humate Ameliorates Abiotic Stress in Arabidopsis thaliana by Increasing Starch Availability	235
Genome-Wide Identification and Comprehensive Analysis of the GASA Gene Family in Peanuts (Arachis hypogaea L.) under Abiotic Stress	234
Comparative RNA-Seq Analysis Revealed Tissue-Specific Splicing Variations during the Generation of the PDX Model	233
Selenium Dibromide Click Chemistry: The Efficient Synthesis of Novel Selenabicyclo[3.3.1]nonene-2 and -nonane Derivatives	230
Novel Loss of Function Variant in BCKDK Causes a Treatable Developmental and Epileptic Encephalopathy	229
Nst1, Densely Associated to P-Body in the Post-Exponential Phases of Saccharomyces cerevisiae, Shows an Intrinsic Potential of Producing Liquid-Like Condensates of P-Body Components in Cells	229
Regulation of Developmental Cell Death in the Animal Kingdom: A Critical Analysis of Epigenetic versus Genetic Factors	229
Petiveria alliacea Reduces Tumor Burden and Metastasis and Regulates the Peripheral Immune Response in a Murine Myeloid Leukemia Model	228
Light-Sensitive Open Channel Block of Ionotropic Glutamate Receptors by Quaternary Ammonium Azobenzene Derivatives	227
Analysis of Functional Single-Nucleotide Polymorphisms (SNPs) and Leaf Quality in Tea Collection under Nitrogen-Deficient Conditions	224
My Name Is Legion, for We Are Many—The Complex Community of Antibody Receptors	223
The Co-Expression Pattern of Calcium-Binding Proteins with γ-Aminobutyric Acid and Glutamate Transporters in the Amygdala of the Guinea Pig: Evidence for Glutamatergic Subpopulations	223
Investigating Antibody Reactivity to the Intestinal Microbiome in Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Feasibility Study	220
Mineralocorticoid Receptor Antagonism Attenuates Multiple Organ Failure after Renal Ischemia and Reperfusion in Mice	219
Regional Differences in Ca2+ Signaling and Transverse-Tubules across Left Atrium from Adult Sheep	218
Optimization of Anthocyanin Production in Tobacco Cells	218
Immunohistochemical Expression Analysis of Caldesmon Isoforms in Colorectal Carcinoma Reveals Interesting Correlations with Tumor Characteristics	217
Effect of Hydrogel Substrate Components on the Stability of Tetracycline Hydrochloride and Swelling Activity against Model Skin Sebum	217
Experimental and Clinical Aspects of Sevoflurane Preconditioning and Postconditioning to Alleviate Hepatic Ischemia-Reperfusion Injury: A Scoping Review	217
Investigating the Modulation of the VTA Neurons in Nicotine-Exposed Pups during Early Maturation Using Optogenetics	216
S100B Affects Gut Microbiota Biodiversity	216
Revealing the Role of Alternariol in the Local Steroidogenesis in Human Prostate Normal and Cancer Cells	211
Antipsychotic Medication Influences the Discriminative Value of Acylethanolamides as Biomarkers of Substance Use Disorder	211
Reverse-Polarization High-Performance Layer Electrochromatography—A New Approach to Anion Separation	210
Advanced Biomarkers of Hepatotoxicity in Psychiatry: A Narrative Review and Recommendations for New Psychoactive Substances	210
Friend or Foe? Locoregional Therapies and Immunotherapies in the Current Hepatocellular Treatment Landscape	208
Galectin-4 Is Involved in the Structural Changes of Glycosphingolipid Glycans in Poorly Differentiated Gastric Cancer Cells with High Metastatic Potential	207
Nitric Oxide Prevents Glioblastoma Stem Cells’ Expansion and Induces Temozolomide Sensitization	207
A Transcriptome-Wide Analysis of Psoriasis: Identifying the Potential Causal Genes and Drug Candidates	205
Mixed-Lineage Leukemia 1 Inhibition Enhances the Differentiation Potential of Bovine Embryonic Stem Cells by Increasing H3K4 Mono-Methylation at Active Promoters	205
Repressive Control of Keratinocyte Cytoplasmic Inflammatory Signaling	204
Long Dynamic β1–β2 Loops in M. tb MazF Toxins Affect the Interaction Modes and Strengths of the Toxin–Antitoxin Pairs	204
Genetic Background of Medication-Related Osteonecrosis of the Jaw: Current Evidence and Future Perspectives	203
Variation in Ants’ Chemical Recognition Signals across Vineyard Agroecosystems	203
Plasma-Functionalized Liquids for Decontamination of Viable Tissues: A Comparative Approach	202
Knockout of the Carbohydrate Responsive Element Binding Protein Enhances Proliferation and Tumorigenesis in Renal Tubules of Mice	201
Structural Dynamics Predominantly Determine the Adaptability of Proteins to Amino Acid Deletions	201
Insights into Cellular Localization and Environmental Influences on the Toxicity of Marine Fish-Killing Flagellate, Heterosigma akashiwo	198
Relationship between GABA-Ergic System and the Expression of Mephedrone-Induced Reward in Rats—Behavioral, Chromatographic and In Vivo Imaging Study	196
Neonatal Meningitis-Causing Escherichia coli Induces Microglia Activation which Acts as a Double-Edged Sword in Bacterial Meningitis	195
Follicular Lymphoma Microenvironment Traits Associated with Event-Free Survival	195
Novel SPEA Superantigen Peptide Agonists and Peptide Agonist-TGFαL3 Conjugate. In Vitro Study of Their Growth-Inhibitory Effects for Targeted Cancer Immunotherapy	194
Versatile and Accessible Magnetic Diagnosis Platform with Different Types of Magnetic Particles for Liquid and Solid Biopsies	193
Influence of Cupric (Cu2+) Ions on the Iron Oxidation Mechanism by DNA-Binding Protein from Starved Cells (Dps) from Marinobacter nauticus	193
Atomic Force Microscopy and High-Resolution Spectrophotometry for Study of Anoxemia and Normoxemia in Model Experiment In Vitro	192
PROTEIN PHOSPHATASE 2C08, a Negative Regulator of Abscisic Acid Signaling, Promotes Internode Elongation in Rice	192
Molecular Mechanism in the Development of Pulmonary Fibrosis in Patients with Sarcoidosis	192
Lung Surfactant Protein B Peptide Mimics Interact with the Human ACE2 Receptor	191
N-N(+) Bond-Forming Intramolecular Cyclization of O-Tosyloxy β-Aminopropioamidoximes and Ion Exchange Reaction for the Synthesis of 2-Aminospiropyrazolilammonium Chlorides and Hexafluorophosphates	191
Targeting SOX18 Transcription Factor Activity by Small-Molecule Inhibitor Sm4 in Non-Small Lung Cancer Cell Lines	190
Impact of Sea Warming and 17-α-Ethinylestradiol Exposure on the Lipid Metabolism of Ruditapes philippinarum Clams	190
Pevonedistat Inhibits SOX2 Expression and Sphere Formation but Also Drives the Induction of Terminal Differentiation Markers and Apoptosis within Arsenite-Transformed Urothelial Cells	189
Myristica fragrans Extract Inhibits Platelet Desialylation and Activation to Ameliorate Sepsis-Associated Thrombocytopenia in a Murine CLP-Induced Sepsis Model	186
RNA Regulatory Networks 2.0	186
State of the Art and New Trends from the 2022 Gism Annual Meeting	185
Effects of Different Types of Recombinant SARS-CoV-2 Spike Protein on Circulating Monocytes’ Structure	183
OPTO-BLUE: An Integrated Bidirectional Optogenetic Lentiviral Platform for Controlled Light-Induced Gene Expression	183
Advances in Immunotherapeutic Approaches to Type 1 Diabetes	182
Hypoxia with or without Treadmill Exercises Affects Slow-Twitch Muscle Atrophy and Joint Destruction in a Rat Model of Rheumatoid Arthritis	181
Development of Procathepsin L (pCTS-L)-Inhibiting Lanosterol-Carrying Liposome Nanoparticles to Treat Lethal Sepsis	180
Apelin Enhances the Effects of Fusobacterium nucleatum on Periodontal Ligament Cells In Vitro	180
Ion and Molecule Transport in Membrane Systems 3.0 and 4.0	180
IDO1 Protein Is Expressed in Diagnostic Biopsies from Both Follicular and Transformed Follicular Patients	178
An Improved RNA Extraction Protocol for Rye Grain Full-Length Transcriptome Sequencing	177
Genome-Wide Identification and Characterization of the Soybean Snf2 Gene Family and Expression Response to Rhizobia	177
Protective Effects of Fasudil Against Cisplatin-Induced Ototoxicity in Zebrafish: An In Vivo Study	176
Gamma-Hemolysin Components: Computational Strategies for LukF-Hlg2 Dimer Reconstruction on a Model Membrane	175
P2Y2 Receptor Signaling in Health and Disease	175
BioGraph: Data Model for Linking and Querying Diverse Biological Metadata	175
Microbial Signatures of Obesity-Aggravated Psoriasis: Insights from an Imiquimod-Based Mouse Model	174
Analysis of SIRT1 Gene SNPs and Clinical Characteristics in Medication-Related Osteonecrosis of the Jaw	174
Nutrient-Enriched Germinated Brown Rice Alters the Intestinal Ecological Network by Regulating Lipid Metabolism in Rats	173
The Traits of the Regenerative Potential of Platelet-Rich Plasma from Donors with Type 1 and Type 2 Diabetes Mellitus	172
Preliminary Preclinical Evaluation of Innovative Bone Scaffolds Composed of Natural Sources–Whey Protein Isolate and Pearl Powder	170
Low-Temperature Uniaxial Orientation Effect on the Structure and Piezoelectric Properties of the Vinylidene Fluoride-Tetrafluoroethylene Copolymer Films	169
Bacterial Systematic Genetics and Integrated Multi-Omics: Beyond Static Genomics Toward Predictive Models	169
Unlocking the Potential of Spheroids in Personalized Medicine: A Systematic Review of Seeding Methodologies	168
Mechanisms Underlying Radioresistance and Reversal Strategies in Non-Small Cell Lung Cancer	168
Identification and Characterization of a Translational Mouse Model for Blood–Brain Barrier Leakage in Cerebral Small Vessel Disease	167
Identification of Drug Repurposing Candidates for Coxsackievirus B3 Infection in iPSC-Derived Brain-like Endothelial Cells	166

Characterisation of Four New Genes in the Ovine KAP19 Family	165
Protective Effects of Regular Physical Activity: Differential Expression of FGF21, GDF15, and Their Receptors in Trained and Untrained Individuals	165
Strategies to Develop Na,K-ATPase-α4 Inhibitors as Male Contraceptives	165
Exploring the Impact of TP53 Mutation and Wild-Type Status on the Efficacy of Immunotherapy in Non-Small Cell Lung Cancer	165
Comprehensive Anatomical Staging Predicts Clinical Progression in Mild Cognitive Impairment: A Data-Driven Approach	165
Metabolomic Analysis Provides Insights into Bud Paradormancy in Camellia sinensis cv. Huangdan	164
Optimization of Loop-Mediated Isothermal Amplification (LAMP) for the Rapid Detection of Nosocomial Pathogens on Environmental Surfaces	164
The Role of Fibroblasts in Melanoma Development: From Tumor Microenvironment Remodeling to Pre-Metastatic Niche Formation	163
Myostatin Modulation in Spinal Muscular Atrophy: A Systematic Review of Preclinical and Clinical Evidence	163