International Journal of Molecular Sciences

Papers
(The H4-Index of International Journal of Molecular Sciences is 139. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)
ArticleCitations
Pathophysiology of Type 2 Diabetes Mellitus1148
The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies853
NRF2, a Transcription Factor for Stress Response and Beyond720
Analytical Methods Used in Determining Antioxidant Activity: A Review694
The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases688
Macrophage Polarization States in the Tumor Microenvironment631
Silver Nanoparticles and Their Antibacterial Applications613
The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics583
Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives528
Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms515
Metabolic Syndrome: Updates on Pathophysiology and Management in 2021472
TNMplot.com: A Web Tool for the Comparison of Gene Expression in Normal, Tumor and Metastatic Tissues465
Nutritional Indices for Assessing Fatty Acids: A Mini-Review432
Short-Chain Fatty Acids and Their Association with Signalling Pathways in Inflammation, Glucose and Lipid Metabolism421
Regulation of Plant Responses to Salt Stress417
Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer382
Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020377
Pseudomonas aeruginosa Biofilms371
A Review of Exosomal Isolation Methods: Is Size Exclusion Chromatography the Best Option?343
PI3K/AKT/mTOR Signaling Pathway in Breast Cancer: From Molecular Landscape to Clinical Aspects340
The MTT Assay: Utility, Limitations, Pitfalls, and Interpretation in Bulk and Single-Cell Analysis338
ROS Homeostasis in Abiotic Stress Tolerance in Plants319
Neuroinflammatory Mechanisms in Ischemic Stroke: Focus on Cardioembolic Stroke, Background, and Therapeutic Approaches317
The Flavonoid Biosynthesis Network in Plants312
Current and Future Development in Lung Cancer Diagnosis289
Fabrication and Applications of Microfluidic Devices: A Review285
Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis281
Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors270
Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases258
Pathophysiology of Atherosclerosis256
A New Era of Antibiotics: The Clinical Potential of Antimicrobial Peptides255
Cytochrome P450 Enzymes and Drug Metabolism in Humans252
An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases244
Regulation of Reactive Oxygen Species and Antioxidant Defense in Plants under Salinity241
Safe Nanoparticles: Are We There Yet?232
Cytokines and Chemokines Involved in Osteoarthritis Pathogenesis230
Regulation of ROS Metabolism in Plants under Environmental Stress: A Review of Recent Experimental Evidence229
Ferroptosis Mechanisms Involved in Neurodegenerative Diseases226
Chronic Low Grade Inflammation in Pathogenesis of PCOS225
Hepcidin-Ferroportin Interaction Controls Systemic Iron Homeostasis225
Silk Fibroin as a Functional Biomaterial for Tissue Engineering222
Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases218
Potential Mechanisms of Bisphenol A (BPA) Contributing to Human Disease217
Cinnamic Acid Derivatives and Their Biological Efficacy212
Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update208
Neuroprotective Effect of Antioxidants in the Brain207
Function and Mechanism of Jasmonic Acid in Plant Responses to Abiotic and Biotic Stresses204
Multiple Functions of MYB Transcription Factors in Abiotic Stress Responses204
Tumor Immune Microenvironment and Immunosuppressive Therapy in Hepatocellular Carcinoma: A Review203
The Immune Functions of Keratinocytes in Skin Wound Healing203
Regulation of Filaggrin, Loricrin, and Involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: Pathogenic Implications in Atopic Dermatitis201
CRISPR-Cas9 DNA Base-Editing and Prime-Editing200
Rhizosphere Bacteria in Plant Growth Promotion, Biocontrol, and Bioremediation of Contaminated Sites: A Comprehensive Review of Effects and Mechanisms199
Advances in Chitosan-Based Nanoparticles for Drug Delivery199
A Review of the Common Neurodegenerative Disorders: Current Therapeutic Approaches and the Potential Role of Nanotherapeutics198
Ferroptosis in Liver Diseases: An Overview197
Terpenes and Terpenoids in Plants: Interactions with Environment and Insects196
CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4196
Recent Updates of Diagnosis, Pathophysiology, and Treatment on Osteoarthritis of the Knee195
Ionic Liquids Toxicity—Benefits and Threats193
Biological Properties and Prospects for the Application of Eugenol—A Review190
Lactic Acid and an Acidic Tumor Microenvironment suppress Anticancer Immunity188
mRNA Vaccine Era—Mechanisms, Drug Platform and Clinical Prospection188
MYB-Mediated Regulation of Anthocyanin Biosynthesis187
Inflammation-Related Biomarkers for the Prediction of Prognosis in Colorectal Cancer Patients186
Neurodegeneration and Inflammation—An Interesting Interplay in Parkinson’s Disease186
Role of Cadherins in Cancer—A Review186
Factors Influencing the Antibacterial Activity of Chitosan and Chitosan Modified by Functionalization185
Osteocyte-Related Cytokines Regulate Osteoclast Formation and Bone Resorption185
Oxidative Stress, Plant Natural Antioxidants, and Obesity185
CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of Receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 Ligands184
Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases183
3D Cell Culture Systems: Tumor Application, Advantages, and Disadvantages183
Plant Responses to Heat Stress: Physiology, Transcription, Noncoding RNAs, and Epigenetics181
Spheroids as a Type of Three-Dimensional Cell Cultures—Examples of Methods of Preparation and the Most Important Application180
Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2180
Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action180
Chitosan and Cellulose-Based Hydrogels for Wound Management179
Molecular Biological and Clinical Understanding of the Pathophysiology and Treatments of Hyperuricemia and Its Association with Metabolic Syndrome, Cardiovascular Diseases and Chronic Kidney Disease179
MicroRNA-Based Diagnosis and Therapy177
Peripheral Nerve Regeneration and Muscle Reinnervation177
Liquid–Liquid Phase Separation in Crowded Environments175
Tryptophan Metabolism and Gut-Brain Homeostasis174
Endothelial Dysfunction, Inflammation and Coronary Artery Disease: Potential Biomarkers and Promising Therapeutical Approaches174
Molecular Mechanisms of Atopic Dermatitis Pathogenesis172
Mechanism of Antimicrobial Peptides: Antimicrobial, Anti-Inflammatory and Antibiofilm Activities172
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements171
Cytokine Networks in the Pathogenesis of Rheumatoid Arthritis171
On Iron Metabolism and Its Regulation170
Trichoderma: The Current Status of Its Application in Agriculture for the Biocontrol of Fungal Phytopathogens and Stimulation of Plant Growth170
Gut Microbiota and Intestinal Trans-Epithelial Permeability168
Targeting Molecular Mechanisms Underlying Treatment Efficacy and Resistance in Osteosarcoma: A Review of Current and Future Strategies168
Plant Secondary Metabolites as Defense Tools against Herbivores for Sustainable Crop Protection166
Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials166
CD4 T Helper Cell Subsets and Related Human Immunological Disorders165
Regulation of Osteoblast Differentiation by Cytokine Networks164
The Significance of Mitochondrial Dysfunction in Cancer164
Glutathione in the Brain163
Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis162
Role of Insulin Resistance in MAFLD162
Anti-Angiogenic Therapy: Current Challenges and Future Perspectives162
Monoterpenes and Their Derivatives—Recent Development in Biological and Medical Applications161
Neuroinflammation in Cerebral Ischemia and Ischemia/Reperfusion Injuries: From Pathophysiology to Therapeutic Strategies160
Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis160
Autophagy and Autophagy-Related Diseases: A Review159
Various Aspects of Calcium Signaling in the Regulation of Apoptosis, Autophagy, Cell Proliferation, and Cancer159
Tissue-Specific Decellularization Methods: Rationale and Strategies to Achieve Regenerative Compounds159
Advances in De Novo Drug Design: From Conventional to Machine Learning Methods158
Ischemic Heart Disease Pathophysiology Paradigms Overview: From Plaque Activation to Microvascular Dysfunction158
Functions of Osteocalcin in Bone, Pancreas, Testis, and Muscle157
Exosomes in Angiogenesis and Anti-angiogenic Therapy in Cancers156
Inflammatory Response Mechanisms of the Dentine–Pulp Complex and the Periapical Tissues156
Cell Death in Liver Diseases: A Review156
Recent Updates of Transarterial Chemoembolilzation in Hepatocellular Carcinoma152
Interaction of Intestinal Bacteria with Human Rotavirus during Infection in Children151
Use of H2O2 to Cause Oxidative Stress, the Catalase Issue151
FLASH Radiotherapy: Current Knowledge and Future Insights Using Proton-Beam Therapy151
Ovarian Cancer Immunotherapy and Personalized Medicine151
An Update on Vitamin D Metabolism151
Matrix Metalloproteinases Shape the Tumor Microenvironment in Cancer Progression150
Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature)150
Switching from Apoptosis to Pyroptosis: Gasdermin-Elicited Inflammation and Antitumor Immunity148
Existence of SARS-CoV-2 Entry Molecules in the Oral Cavity147
Osteoporosis Due to Hormone Imbalance: An Overview of the Effects of Estrogen Deficiency and Glucocorticoid Overuse on Bone Turnover147
Mechanisms of Abscisic Acid-Mediated Drought Stress Responses in Plants146
Chronic and Cycling Hypoxia: Drivers of Cancer Chronic Inflammation through HIF-1 and NF-κB Activation: A Review of the Molecular Mechanisms146
Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action146
Gut Microbiota Metabolites in NAFLD Pathogenesis and Therapeutic Implications146
Copper Dyshomeostasis in Neurodegenerative Diseases—Therapeutic Implications145
Vitamin D and Cardiovascular Disease, with Emphasis on Hypertension, Atherosclerosis, and Heart Failure145
The Immune Microenvironment in Pancreatic Cancer145
Cancer Cell Metabolism in Hypoxia: Role of HIF-1 as Key Regulator and Therapeutic Target144
Bone Microenvironment and Osteosarcoma Metastasis143
Interactions of Gold and Silver Nanoparticles with Bacterial Biofilms: Molecular Interactions behind Inhibition and Resistance143
Mechanisms and Regulation of Cellular Senescence142
Clinical Application of Bone Marrow Mesenchymal Stem/Stromal Cells to Repair Skeletal Tissue141
New Treatment Addressing the Pathogenesis of Psoriasis141
Plant-Derived Antioxidants: Significance in Skin Health and the Ageing Process140
Possible Neuroprotective Mechanisms of Physical Exercise in Neurodegeneration139
Tumor-Associated Macrophages (TAMs) in Colorectal Cancer (CRC): From Mechanism to Therapy and Prognosis139
Gut–Brain Axis: Role of Gut Microbiota on Neurological Disorders and How Probiotics/Prebiotics Beneficially Modulate Microbial and Immune Pathways to Improve Brain Functions139
Molecular Mechanisms and Emerging Therapeutics for Osteoporosis139
The Role of Oxidative Stress in Pancreatic β Cell Dysfunction in Diabetes139
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