International Journal of Molecular Sciences

Article	Citations
Biofilm-Associated Amyloid Proteins Linked with the Progression of Neurodegenerative Diseases	904
Identification and Characterization of Histone Modification Gene Families and Their Expression Patterns During Pod and Seed Development in Peanut	722
Mechanisms of Viral Degradation of Cellular Signal Transducer and Activator of Transcription 2	622
Intrinsic Expression of Coagulation Factors and Protease Activated Receptor 1 (PAR1) in Photoreceptors and Inner Retinal Layers	621
Immunomodulatory Arming Factors—The Current Paradigm for Oncolytic Vectors Relies on Immune Stimulating Molecules	607
Amyotrophic Lateral Sclerosis as a Systemic Disease	603
Effects of CSN1/CSN2 Mutants in Flavonoid Metabolism on Rice (Oryza sativa L.)	581
Plasma Exosomal-Derived SERPINA1 and GNAI2 Downregulation as Potential Diagnostic Biomarkers of Kawasaki Disease with Coronary Artery Aneurysms	577
Genome-Wide Identification and Functional Characterization of the Dof Family in Dendrobium officinale	568
Cultured Macrophage Models for the Investigation of Lysosomal Glucocerebrosidase and Gaucher Disease	525
Multifunctional Nanocomposite Hydrogel with Enhanced Chemodynamic Therapy and Starvation Therapy for Inhibiting Postoperative Tumor Recurrence	474
Botryococcus terribilis Ethanol Extract Exerts Anti-inflammatory Effects on Murine RAW264 Cells	461
Special Issue “Neuromodulatory Effects of Serotonin”	421
Inflammatory Stimulation Upregulates the Receptor Transporter Protein 4 (RTP4) in SIM-A9 Microglial Cells	405
New Horizons in the Diagnosis of Gastric Cancer: The Importance of Selected Toll-like Receptors in Immunopathogenesis Depending on the Stage, Clinical Subtype, and Gender of Newly Diagnosed Patients	400
miR-17-5p-Mediated RNA Activation Upregulates KPNA2 Expression and Inhibits High-Glucose-Induced Apoptosis of Sheep Granulosa Cells	393
Investigation of Impact of Oxidative Stress on Human Periodontal Ligament Cells Exposed to Static Compression	389
Knockout of the Carbohydrate Responsive Element Binding Protein Enhances Proliferation and Tumorigenesis in Renal Tubules of Mice	385
Genetic Diversity Analysis and Identification of Candidate Genes for Growth Traits in Chengkou Mountain Chicken	384
The Long-Distance Transport of Jasmonates in Salt-Treated Pea Plants and Involvement of Lipid Transfer Proteins in the Process	380
Causal Relationship Between Physical Activity and Thymic Tumors Mediated by Circulating Cytokines: A Mendelian Randomization Mediation Analysis	374
Expression of Neurotrophins and Its Receptors During Fetal Development in the Human Cochlea	361
Adeno-Associated Viral Vectors in the Treatment of Epilepsy	360
Plasma Cells as the Key Players of IVF Failure? Unlocking the Enigma of Infertility and In Vitro Fertilization Failure in the Light of Uterine Inflammation	351
Engineered M13-Derived Bacteriophages Capable of Gold Nanoparticle Synthesis and Nanogold Manipulations	339

Highly Specific Polyphenolic Colloids as Alternatives to Antimicrobials in Livestock Production	336
An Improved RNA Extraction Protocol for Rye Grain Full-Length Transcriptome Sequencing	334
Comparative Analysis of Commercial and Home-Made Media on RSPO1/S6R Axis in Organoids with Different Wnt Backgrounds: A Methodological Guide for the Selection of Intestinal Patient-Derived Organoids C	330
Reciprocal Dynamics of Metabolism and mRNA Translation in Tumor Angiogenesis	326
Exploring Cannabidiol (CBD) and Cannabigerol (CBG) Safety Profile and Skincare Potential	316
The Evolution of the WUSCHEL-Related Homeobox Gene Family in Dendrobium Species and Its Role in Sex Organ Development in D. chrysotoxum	310
Unraveling Differences in Molecular Mechanisms and Immunological Contrasts between Squamous Cell Carcinoma and Adenocarcinoma of the Cervix	310
Proteome Changes Induced by Iprodione Exposure in the Pesticide-Tolerant Pseudomonas sp. C9 Strain Isolated from a Biopurification System	306
Mixed-Lineage Leukemia 1 Inhibition Enhances the Differentiation Potential of Bovine Embryonic Stem Cells by Increasing H3K4 Mono-Methylation at Active Promoters	303
Role of Adipose Tissue Hormones in Pathogenesis of Cryptoglandular Anal Fistula	301
PCSK9 Expression in Vascular Smooth Muscle Cells: Role of Insulin Resistance and High Glucose	293
G-Quadruplex Structures Formed by Human Telomere and C9orf72 GGGGCC Repeats	292
Novel Assignment of Gene Markers to Hematological and Immune Cells Based on Single-Cell Transcriptomics	279
Mechanism of Functional Compound Fruit Drinks in Regulating Serum Metabolism in Constipated Mice	272
Characterization of the Activities of Vorinostat Against Toxoplasma gondii	268
Loss of Myostatin Affects m6A Modification but Not Semen Characteristics in Bull Spermatozoa	262
Hepatoprotective Activity of Nature-Derived Polyphenols Studied by Mass Spectrometry Based Multi-OMICS Approach	260
Role of Human DNA Ligases in Mediating Pharmacological Activities of Flavonoids	259
Alterations in Methionine Cycle and Wnt/MAPK Signaling Associated with HMBi-Induced Cashmere Growth in Goats	259
Tracking the Evolution of Cutaneous Melanoma by Multiparameter Flow Sorting and Genomic Profiling	257
Simultaneous Inhibition of PD-1 and Stimulation of CD40 Signaling Pathways by Anti-PD-L1/CD40L Bispecific Fusion Protein Synergistically Activate Target and Effector Cells	257
Structure–Tissue Exposure/Selectivity Relationship (STR) on Carbamates of Cannabidiol	256
PET Molecular Imaging: Old Habits Do Not Die, They Only Evolve into New Applications	256
Repressive Control of Keratinocyte Cytoplasmic Inflammatory Signaling	252
Differentially Expressed Genes Involved in Primary Resistance to Immunotherapy in Patients with Advanced-Stage Pulmonary Cancer	252
Blood Proteome Profiling Reveals Biomarkers and Pathway Alterations in Fragile X PM at Risk for Developing FXTAS	247
The Apple Mitogen-Activated Protein Kinase MdMAPK6 Increases Drought, Salt, and Disease Resistance in Plants	245
Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer	245
Expression of the C-Terminal Domain of Phospholipase Cβ3 Inhibits Signaling via Gαq-Coupled Receptors and Transient Receptor Potential Channels	245
Super-Resolution Imaging of the A- and B-Type Lamin Networks: A Comparative Study of Different Fluorescence Labeling Procedures	243
Stress-Induced Changes in Nucleocytoplasmic Localization of Crucial Factors in Gene Expression Regulation	242
Sickle Cell Disease and Gut Health: The Influence of Intestinal Parasites and the Microbiome on Angolan Children	242
Synthesis of Mixed Phosphonate Esters and Amino Acid-Based Phosphonamidates, and Their Screening as Herbicides	240
Modulation of the Oncogenic LINE-1 Regulatory Network in Non-Small Cell Lung Cancer by Exosomal miRNAs	236
Bioinformatics Insights on Viral Gene Expression Transactivation: From HIV-1 to SARS-CoV-2	234
Upregulated Nuclear Expression of Soluble Epoxide Hydrolase Predicts Poor Outcome in Breast Cancer Patients: Importance of the Digital Pathology Approach	233
Molecular Analysis of PIK3CA in Metastatic Hormone Receptor-Positive Breast Cancer in Chile: Clinical and Pathological Insights	232
Molecular Alterations Associated with Histologically Overt Stromal Response in Patients with Prostate Cancer	231
Mica Lattice Orientation of Epitaxially Grown Amyloid β25–35 Fibrils	230
Recent Advances in Cellulose Chemistry	230
Protective Effects of Fasudil Against Cisplatin-Induced Ototoxicity in Zebrafish: An In Vivo Study	229
Efficient Production of Recombinant Human Brain-Derived Neurotrophic Factor in Escherichia coli Through the Engineering of Its Pro-Region	227
Advancements in the Research of New Modulators of Nitric Oxide Synthases Activity	227
Elevated Hippocampal CRMP5 Mediates Chronic Stress-Induced Cognitive Deficits by Disrupting Synaptic Plasticity, Hindering AMPAR Trafficking, and Triggering Cytokine Release	226
Advances in Immunotherapeutic Approaches to Type 1 Diabetes	223
Prenatal and Neonatal Pulmonary Thrombosis as a Potential Complication of SARS-CoV-2 Infection in Late Pregnancy	223
New Advances in Diabetes Genetics	222
Lack of Association between Common LAG3/CD4 Variants and Risk of Migraine	222
Gut Microbiota Alterations and Primary Glomerulonephritis in Children: A Review	221
Engineered Bone Marrow Stem Cell-Sheets Alleviate Renal Damage in a Rat Chronic Glomerulonephritis Model	217

Dissecting Immunotherapy Strategies for Small Cell Lung Cancer: Antibodies, Ionizing Radiation and CAR-T	217
Serum Concentrations and Dietary Intake of Vitamin B12 in Children and Adolescents on Metformin: A Case–Control Study	214
Reverse-Polarization High-Performance Layer Electrochromatography—A New Approach to Anion Separation	214
Substituent Effects of the Nitrogen Heterocycle on Indole and Quinoline HDN Performance: A Combination of Experiments and Theoretical Study	214
Synthesis of 1-(2-Hydroxyphenyl)- and (3,5-Dichloro-2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic Acid Derivatives as Promising Scaffolds for the Development of Novel Antimicrobial and Anticancer Age	210
Regional Differences in Ca2+ Signaling and Transverse-Tubules across Left Atrium from Adult Sheep	209
Polymeric Interlayer in CdS-Free Electron-Selective Contact for Sb2Se3 Thin-Film Solar Cells	209
UV Laser-Induced Phototransformations of Matrix-Isolated 5-Chloro-3-nitro-2-hydroxyacetophenone	208
An Efficient 5-Aminolevulinic Acid Photodynamic Therapy Treatment for Human Hepatocellular Carcinoma	207
Effects of Probiotics on Colitis-Induced Exacerbation of Alzheimer’s Disease in AppNL-G-F Mice	207
Fast Recombination of Charge-Transfer State in Organic Photovoltaic Composite of P3HT and Semiconducting Carbon Nanotubes Is the Reason for Its Poor Photovoltaic Performance	206
A New Signature That Predicts Progression-Free Survival of Clear Cell Renal Cell Carcinoma with Anti-PD-1 Therapy	204
IDO1 Protein Is Expressed in Diagnostic Biopsies from Both Follicular and Transformed Follicular Patients	202
The Co-Expression Pattern of Calcium-Binding Proteins with γ-Aminobutyric Acid and Glutamate Transporters in the Amygdala of the Guinea Pig: Evidence for Glutamatergic Subpopulations	201
Relationship between GABA-Ergic System and the Expression of Mephedrone-Induced Reward in Rats—Behavioral, Chromatographic and In Vivo Imaging Study	200
Follicular Lymphoma Microenvironment Traits Associated with Event-Free Survival	200
GUS Reporter-Aided Promoter Deletion Analysis of A. thaliana POLYAMINE OXIDASE 3	200
Comparative Study of Chemical Stability of a PK20 Opioid–Neurotensin Hybrid Peptide and Its Analogue [Ile9]PK20—The Effect of Isomerism of a Single Amino Acid	199
CCP1, a Regulator of Tubulin Post-Translational Modifications, Potentially Plays an Essential Role in Cerebellar Development	199
Phenotypic and Genotypic Virulence Characterisation of Staphylococcus pettenkoferi Strains Isolated from Human Bloodstream and Diabetic Foot Infections	198
Reported Cases and Diagnostics of Occupational Insect Allergy: A Systematic Review	198
Dimerisation of the Yeast K+ Translocation Protein Trk1 Depends on the K+ Concentration	197
Rapid Detection of Brettanomyces bruxellensis in Wine by Polychromatic Flow Cytometry	195
The Comparative Survey of Coordinated Regulation of Steroidogenic Pathway in Japanese Flounder (Paralichthys olivaceus) and Chinese Tongue Sole (Cynoglossus semilaevis)	191
Metastatic Melanoma Progression Is Associated with Endothelial Nitric Oxide Synthase Uncoupling Induced by Loss of eNOS:BH4 Stoichiometry	191
Hematopoietic Disorders, Renal Impairment and Growth in Mucopolysaccharidosis-Plus Syndrome	191
Identifying QTLs for Grain Size in a Colossal Grain Rice (Oryza sativa L.) Line, and Analysis of Additive Effects of QTLs	191
Ab Initio Study of the Interaction of a Graphene Surface Decorated with a Metal-Doped C30 with Carbon Monoxide, Carbon Dioxide, Methane, and Ozone	188
Live-Cell Imaging of Single Neurotrophin Receptor Molecules on Human Neurons in Alzheimer’s Disease	187
Analysis of the Biological Properties of Blood Plasma Protein with GcMAF Functional Activity	187
The RyR1 P3528S Substitution Alters Mouse Skeletal Muscle Contractile Properties and RyR1 Ion Channel Gating	186
Cholestatic HCV Cryoglobulinemia: A New Clinical and Pathological Entity before and after Direct-Acting Antiviral Therapies—A Case-Control Study	185
Impact of Sea Warming and 17-α-Ethinylestradiol Exposure on the Lipid Metabolism of Ruditapes philippinarum Clams	185
Molecular Insights into the Accelerated Sprouting of and Apical Dominance Release in Potato Tubers Subjected to Post-Harvest Heat Stress	184
Mass Spectrometric Proteomics 2.0	184
No Substrate Left behind—Mining of Shotgun Proteomics Datasets Rescues Evidence of Proteolysis by SARS-CoV-2 3CLpro Main Protease	184
Characterization and Potential Action Mode Divergences of Homologous ACO1 Genes during the Organ Development and Ripening Process between Non-Climacteric Grape and Climacteric Peach	183
Do Arabinogalactan Proteins Occur in the Transfer Cells of Utricularia dichotoma?	182
Candidate Genes for IgA Nephropathy in Pediatric Patients: Exome-Wide Association Study	182
Molecular Characterization and Mutational Analysis of Clarithromycin- and Levofloxacin-Resistance Genes in Helicobacter pylori from Gastric Biopsies in Southern Croatia	180
The Solvation Effect of C=O Group of Cyclic Anhydrides in Solution	179
Lung Surfactant Protein B Peptide Mimics Interact with the Human ACE2 Receptor	179
Polyacrylic-Coated Solid Nanoparticles Increase the Aquaporin Permeability to Hydrogen Peroxide	178
Ageing-Related Alterations in Renal Epithelial Glucose Transport	177
Two Different Isocitrate Dehydrogenases from Pseudomonas aeruginosa: Enzymology and Coenzyme-Evolutionary Implications	177
Photonics of Some Monomethine Cyanine Dyes in Solutions and in Complexes with Biomolecules	177
MicroRNA Targets PAP1 to Mediate Melanization in Plutella xylostella (Linnaeus) Infected by Metarhizium anisopliae	176
Effects of Different Types of Recombinant SARS-CoV-2 Spike Protein on Circulating Monocytes’ Structure	176
Special Issue “Mitochondrial Respiration in Physiology and Pathology”	175
GV1001 Inhibits the Severity of the Ligature-Induced Periodontitis and the Vascular Lipid Deposition Associated with the Periodontitis in Mice	175
Two-Component System Genes in Brassica napus: Identification, Analysis, and Expression Patterns in Response to Abiotic and Biotic Stresses	175
Discovery of Novel Amino Acids (Analogues)-Substituted Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Design, Synthesis, and Biological Evaluat	175
Reverse Onco-Cardiology: What Is the Evidence for Breast Cancer? A Systematic Review of the Literature	175
Design of Two New Sulfur Derivatives of Perezone: In Silico Study Simulation Targeting PARP-1 and In Vitro Study Validation Using Cancer Cell Lines	174
Teratoma Development in 129.MOLF-Chr19 Mice Elicits Two Waves of Immune Cell Infiltration	173
Bacterial Production of CDKL5 Catalytic Domain: Insights in Aggregation, Internal Translation and Phosphorylation Patterns	173
Ex Vivo Optimization of Donor Lungs with Inhaled Sevoflurane during Normothermic Ex Vivo Lung Perfusion (VITALISE): A Pilot and Feasibility Study in Sheep	171
Infection vs. Reinfection: The Immunomodulation of Erythropoiesis	171
Preliminary Study on the Formation Mechanism of Malformed Sweet Cherry (Prunus avium L.) Fruits in Southern China Using Transcriptome and Metabolome Data	169
Carvacrol as a Stimulant of the Expression of Key Genes of the Ginsenoside Biosynthesis Pathway and Its Effect on the Production of Ginseng Saponins in Panax quinquefolium Hairy Root Cultures	169
Nebulized Lipopolysaccharide Causes Delayed Cortical Neuroinflammation in a Murine Model of Acute Lung Injury	168
Novel Techniques for Mapping DNA Damage and Repair in the Brain	168
The Involvement of Cysteine-X-Cysteine Motif Chemokine Receptors in Skin Homeostasis and the Pathogenesis of Allergic Contact Dermatitis and Psoriasis	167
Comparative RNA-Seq Analysis Revealed Tissue-Specific Splicing Variations during the Generation of the PDX Model	167
Health-Promoting Properties of Natural Flavonol Glycosides Isolated from Staphylea pinnata L.	166
What Can Be Learned by Knowing Only the Amino Acid Composition of Proteins?	165
The Genetic Profile of Large B-Cell Lymphomas Presenting in the Ocular Adnexa	164
Liquid Chromatographic Enantioseparation of Newly Synthesized Fluorinated Tryptophan Analogs Applying Macrocyclic Glycopeptides-Based Chiral Stationary Phases Utilizing Core-Shell Particles	164
VRK1 Regulates Sensitivity to Oxidative Stress by Altering Histone Epigenetic Modifications and the Nuclear Phosphoproteome in Tumor Cells	163
The Impact of Serum/Plasma Proteomics on SARS-CoV-2 Diagnosis and Prognosis	163
Conjugated Human Serum Albumin/Gold-Silica Nanoparticles as Multifunctional Carrier of a Chemotherapeutic Drug	163
Role of Polymer Concentration on the Release Rates of Proteins from Single- and Double-Network Hydrogels	163
Lung Inflammatory Phenotype in Mice Deficient in Fibulin-2 and ADAMTS-12	163
The Role of Natural Products in Immunopharmacology	163
Theoretical and Experimental Study of Different Side Chains on 3,4-Ethylenedioxythiophene and Diketopyrrolopyrrole-Derived Polymers: Towards Organic Transistors	162
The Effect of Alternative Splicing Sites on Mirtron Formation and Arm Selection of Precursor microRNAs	162
Effect of Synthetic Vitreous Fiber Exposure on TMEM16A Channels in a Xenopus laevis Oocyte Model	161
Selective Removal of Chlorophyll and Isolation of Lutein from Plant Extracts Using Magnetic Solid Phase Extraction with Iron Oxide Nanoparticles	161
Highly Calibrated Relationship Between Bleomycin Concentrations and Facets of the Active Phase Fibrosis in Classical Mouse Bleomycin Model	161
The Expression of Toll-like Receptors (TLR7 and TLR9) in Class III and Class IV of Recently Diagnosed Lupus Nephritis with 12-Month Follow-Up	160

An Optimized Method for LC–MS-Based Quantification of Endogenous Organic Acids: Metabolic Perturbations in Pancreatic Cancer	160
Assessing the Potential of an Enzymatically Liberated Salmon Oil to Support Immune Health Recovery from Acute SARS-CoV-2 Infection via Change in the Expression of Cytokine, Chemokine and Interferon-Re	159
Single Nucleotide Polymorphisms on Toll-like Receptor-4 and the Risk of Developing Skin Cancer	159
Precise and Accurate DNA-3′/5-Ends Polishing with Thermus thermophilus Phage vb_Tt72 DNA Polymerase	158
Advanced SnO2 Thin Films: Stability and Sensitivity in CO Detection	158