OOIR: Observatory of International Research

Papers

(The H4-Index of Cellular and Molecular Life Sciences is 55. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Human pancreatic ductal organoids with controlled polarity provide a novel ex vivo tool to study epithelial cell physiology	207
Cellular interactions in the pituitary stem cell niche	207
Role for animal models in understanding essential fatty acid deficiency in cystic fibrosis	157
Re-expression of epigenetically silenced PTPRR by histone acetylation sensitizes RAS-mutant lung adenocarcinoma to SHP2 inhibition	145
Unraveling the molecular interactions between α7 nicotinic receptor and a RIC3 variant associated with backward speech	140
B3galt5 deficiency attenuates hepatocellular carcinoma by suppressing mTOR/p70s6k-mediated glycolysis	136
Vitamin B12 ameliorates gut epithelial injury via modulating the HIF-1 pathway and gut microbiota	120
Disrupted mossy fiber connections from defective embryonic neurogenesis contribute to SOX11-associated schizophrenia	117
A C-type lectin induces NLRP3 inflammasome activation via TLR4 interaction in human peripheral blood mononuclear cells	113
Longitudinal metabolomic profiles reveal sex-specific adjustments to long-duration spaceflight and return to Earth	108
AP-1B regulates interactions of epithelial cells and intraepithelial lymphocytes in the intestine	107
TMEM9 activates Rab9-dependent alternative autophagy through interaction with Beclin1	104
CDNF and MANF regulate ER stress in a tissue-specific manner	101
Functional determinants of lysophospholipid- and voltage-dependent regulation of TRPC5 channel	97
Human myelin proteolipid protein structure and lipid bilayer stacking	92
Could the kynurenine pathway be the key missing piece of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) complex puzzle?	88
miR-155 regulates physiological angiogenesis but an miR-155-rich microenvironment disrupts the process by promoting unproductive endothelial sprouting	87
The distinct phenotype of primary adipocytes and adipocytes derived from stem cells of white adipose tissue as assessed by Raman and fluorescence imaging	87
A context-dependent and disordered ubiquitin-binding motif	87
EFHD1 promotes osteosarcoma proliferation and drug resistance by inhibiting the opening of the mitochondrial membrane permeability transition pore (mPTP) by binding to ANT3	85
Collagen VI sustains cell stemness and chemotherapy resistance in glioblastoma	84
TAZ promotes PDX1-mediated insulinogenesis	83
NUMA1 modulates apoptosis of esophageal squamous cell carcinoma cells through regulating ASK1-JNK signaling pathway	81
Notch transcriptional target tmtc1 maintains vascular homeostasis	80
Poly (ADP-ribose) polymerase 1 promotes HuR/ELAVL1 cytoplasmic localization and inflammatory gene expression by regulating p38 MAPK activity	80

Mechano-regulation by clathrin pit-formation and passive cholesterol-dependent tubules during de-adhesion	79
Phospholipid scramblase 1: an essential component of the nephrocyte slit diaphragm	78
IKKα-STAT3-S727 axis: a novel mechanism in DOX-induced cardiomyopathy	78
Zebrafish: an important model for understanding scoliosis	74
MIAT, a potent CVD-promoting lncRNA	73
Role of the GLP2–Wnt1 axis in silicon-rich alkaline mineral water maintaining intestinal epithelium regeneration in piglets under early-life stress	71
Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection	69
Sestrin2 protects against lethal sepsis by suppressing the pyroptosis of dendritic cells	69
DUSP1 interacts with and dephosphorylates VCP to improve mitochondrial quality control against endotoxemia-induced myocardial dysfunction	68
Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage	66
Elucidation of the pluripotent potential of bovine embryonic lineages facilitates the establishment of formative stem cell lines	65
PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity	65
Mechanically guided cell fate determination in early development	65
LSM14B controls oocyte mRNA storage and stability to ensure female fertility	64
Autophagy and apoptosis cascade: which is more prominent in neuronal death?	63
TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice	63
Tuning the ignition of CAR: optimizing the affinity of scFv to improve CAR-T therapy	63
Inositol hexakisphosphate primes syndapin I/PACSIN 1 activation in endocytosis	62
Rescuing tri-heteromeric NMDA receptor function: the potential of pregnenolone-sulfate in loss-of-function GRIN2B variants	60
Cell-specific IL-1R1 regulates the regional heterogeneity of microglial displacement of GABAergic synapses and motor learning ability	60
Accessing the human trophoblast stem cell state from pluripotent and somatic cells	58
Induction of pulmonary HLA-G expression by SARS-CoV-2 infection	58
Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma	57
Keratin 8 is a scaffolding and regulatory protein of ERAD complexes	57
ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response	57
Skeletal muscle cell-specific differences in type 2 diabetes	57
Lactate promotes H3K18 lactylation in human neuroectoderm differentiation	56
Single cell multi-omics of fibrotic kidney reveal epigenetic regulation of antioxidation and apoptosis within proximal tubule	56
Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensors	56
Liver-derived metabolites as signaling molecules in fatty liver disease	55