OOIR: Observatory of International Research

Papers

(The H4-Index of Molecules is 110. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Comprehensive Review on Alzheimer’s Disease: Causes and Treatment	1245
An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation	717
Important Flavonoids and Their Role as a Therapeutic Agent	654
Controlled Drug Delivery Systems: Current Status and Future Directions	608
Plant Flavonoids: Chemical Characteristics and Biological Activity	538
A Review of Liposomes as a Drug Delivery System: Current Status of Approved Products, Regulatory Environments, and Future Perspectives	455
Determination of Antioxidants by DPPH Radical Scavenging Activity and Quantitative Phytochemical Analysis of Ficus religiosa	345
Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects	339
Coriandrum sativum L.: A Review on Ethnopharmacology, Phytochemistry, and Cardiovascular Benefits	336
Industrial Applications of Ionic Liquids	328
Anti-Inflammatory Action and Mechanisms of Resveratrol	325
General Health Benefits and Pharmacological Activities of Triticum aestivum L.	313
Essential Oils as Natural Sources of Fragrance Compounds for Cosmetics and Cosmeceuticals	299
COVID-19: A Global Challenge with Old History, Epidemiology and Progress So Far	298
Nanotechnology: A Revolution in Modern Industry	286
Flavonoids as Potential Anti-Inflammatory Molecules: A Review	284
Bone Grafts and Substitutes in Dentistry: A Review of Current Trends and Developments	279
New Antibiotics for Multidrug-Resistant Bacterial Strains: Latest Research Developments and Future Perspectives	269
Prostate Cancer Review: Genetics, Diagnosis, Treatment Options, and Alternative Approaches	245
Hydrogels: Properties and Applications in Biomedicine	243
Synthesis and Biological Application of Polylactic Acid	242
A Brief History of Colour, the Environmental Impact of Synthetic Dyes and Removal by Using Laccases	234
Heavy Metals and Human Health: Possible Exposure Pathways and the Competition for Protein Binding Sites	225
Machine Learning Methods in Drug Discovery	224
Antibody–Drug Conjugates for Cancer Therapy	223

A Global Review on Short Peptides: Frontiers and Perspectives	221
Role of Cholinergic Signaling in Alzheimer’s Disease	218
Multidrug Resistance (MDR): A Widespread Phenomenon in Pharmacological Therapies	212
Antimicrobial Properties of Chitosan and Chitosan Derivatives in the Treatment of Enteric Infections	211
Modern Approaches in the Discovery and Development of Plant-Based Natural Products and Their Analogues as Potential Therapeutic Agents	202
Nanotechnology in Wastewater Management: A New Paradigm Towards Wastewater Treatment	198
Nanoencapsulation of Promising Bioactive Compounds to Improve Their Absorption, Stability, Functionality and the Appearance of the Final Food Products	198
The Systemic Inflammation Index on Admission Predicts In-Hospital Mortality in COVID-19 Patients	195
Adsorption of Crystal Violet Dye Using Activated Carbon of Lemon Wood and Activated Carbon/Fe3O4 Magnetic Nanocomposite from Aqueous Solutions: A Kinetic, Equilibrium and Thermodynamic Study	191
Plant-Derived Anticancer Compounds as New Perspectives in Drug Discovery and Alternative Therapy	190
Recent Developments in Chitosan-Based Adsorbents for the Removal of Pollutants from Aqueous Environments	190
The Potential of Selected Agri-Food Loss and Waste to Contribute to a Circular Economy: Applications in the Food, Cosmetic and Pharmaceutical Industries	189
A Compressive Review about Taxol®: History and Future Challenges	189
Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance	188
Green Silver and Gold Nanoparticles: Biological Synthesis Approaches and Potentials for Biomedical Applications	187
Antibacterial, Antifungal, Antimycotoxigenic, and Antioxidant Activities of Essential Oils: An Updated Review	185
Factors Affecting Synthetic Dye Adsorption; Desorption Studies: A Review of Results from the Last Five Years (2017–2021)	184
An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy	183
Anthocyanin Pigments: Beyond Aesthetics	181
The Role of Vitamin C, Vitamin D, and Selenium in Immune System against COVID-19	181
Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity	176
Characteristics of the Proteolytic Enzymes Produced by Lactic Acid Bacteria	175
Wearable Biosensors: An Alternative and Practical Approach in Healthcare and Disease Monitoring	174
Plant Secondary Metabolites Produced in Response to Abiotic Stresses Has Potential Application in Pharmaceutical Product Development	173
Role of Lipids in Food Flavor Generation	172
Skin Wound Healing: Normal Macrophage Function and Macrophage Dysfunction in Diabetic Wounds	172
Antimicrobial Activity of Quercetin: An Approach to Its Mechanistic Principle	170
Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis	168
Wine Polyphenol Content and Its Influence on Wine Quality and Properties: A Review	167
Chemical Structure and Biological Activity of Humic Substances Define Their Role as Plant Growth Promoters	167
Bioethanol Production by Enzymatic Hydrolysis from Different Lignocellulosic Sources	162
The Protective Role of Butyrate against Obesity and Obesity-Related Diseases	160
Chitosan Nanoparticles-Insight into Properties, Functionalization and Applications in Drug Delivery and Theranostics	160
Recent Progress in Bioconjugation Strategies for Liposome-Mediated Drug Delivery	159
Thiazole Ring—A Biologically Active Scaffold	158
Antibacterial Effects of Flavonoids and Their Structure-Activity Relationship Study: A Comparative Interpretation	157
Therapeutic Potential of Phenolic Compounds in Medicinal Plants—Natural Health Products for Human Health	157
Health Benefits of Quercetin in Age-Related Diseases	156
Astaxanthin for the Food Industry	154
Antioxidant and Anti-Inflammatory Potential of Polyphenols Contained in Mediterranean Diet in Obesity: Molecular Mechanisms	153
A Review on Natural Fiber Bio-Composites, Surface Modifications and Applications	153
Preparation of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Drug Delivery and the Effects of Preparation Parameters of Solvent Injection Method	152
Biological Properties and Applications of Betalains	149
Health Benefits and Chemical Composition of Matcha Green Tea: A Review	148
Diversity in Chemical Structures and Biological Properties of Plant Alkaloids	148
Recent Achievements in Dyes Removal Focused on Advanced Oxidation Processes Integrated with Biological Methods	147
Role of Monoamine Oxidase Activity in Alzheimer’s Disease: An Insight into the Therapeutic Potential of Inhibitors	143
TiO2 as a Photocatalyst for Water Splitting—An Experimental and Theoretical Review	142
Plant-Derived Pesticides as an Alternative to Pest Management and Sustainable Agricultural Production: Prospects, Applications and Challenges	140
Quercetin Prevents LPS-Induced Oxidative Stress and Inflammation by Modulating NOX2/ROS/NF-kB in Lung Epithelial Cells	140

Subcritical Water Extraction of Natural Products	139
Effect of Dataset Size and Train/Test Split Ratios in QSAR/QSPR Multiclass Classification	139
Berberine as a Potential Anticancer Agent: A Comprehensive Review	138
A New Cd(II)-Based Coordination Polymer for Efficient Photocatalytic Removal of Organic Dyes	137
Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals	137
The Development of Maillard Reaction, and Advanced Glycation End Product (AGE)-Receptor for AGE (RAGE) Signaling Inhibitors as Novel Therapeutic Strategies for Patients with AGE-Related Diseases	137
A Critical Review on Pulsed Electric Field: A Novel Technology for the Extraction of Phytoconstituents	134
Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity—An Update and Forward Look	134
Discovery, Development, and Patent Trends on Molnupiravir: A Prospective Oral Treatment for COVID-19	133
Role of Gut Microbiota, Probiotics and Prebiotics in the Cardiovascular Diseases	131
Mechanistic Insight into Oxidative Stress-Triggered Signaling Pathways and Type 2 Diabetes	131
Dietary Plant Polyphenols: Effects of Food Processing on Their Content and Bioavailability	129
Selenium Biofortification: Roles, Mechanisms, Responses and Prospects	129
Astaxanthin and its Effects in Inflammatory Responses and Inflammation-Associated Diseases: Recent Advances and Future Directions	127
Natural-Based Hydrogels for Tissue Engineering Applications	126
Different Schiff Bases—Structure, Importance and Classification	126
pH-Sensitive Biomaterials for Drug Delivery	124
Excited-State Intramolecular Proton Transfer: A Short Introductory Review	123
Evaluation of Peptide/Protein Self-Assembly and Aggregation by Spectroscopic Methods	123
Natural Products as Anticancer Agents: Current Status and Future Perspectives	121
Antibody–Drug Conjugates—A Tutorial Review	120
Soluble Dietary Fiber, One of the Most Important Nutrients for the Gut Microbiota	120
Neuroinflammatory Markers: Key Indicators in the Pathology of Neurodegenerative Diseases	119
Major Phytochemicals: Recent Advances in Health Benefits and Extraction Method	118
Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents	117
Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities	117
Merging Ligand-Based and Structure-Based Methods in Drug Discovery: An Overview of Combined Virtual Screening Approaches	115
Progresses in Food Packaging, Food Quality, and Safety—Controlled-Release Antioxidant and/or Antimicrobial Packaging	115
Nanoformulations to Enhance the Bioavailability and Physiological Functions of Polyphenols	114
Neuroprotective Effect of SGLT2 Inhibitors	114
Facile Tailoring of Structures for Controlled Release of Paracetamol from Sustainable Lignin Derived Platforms	113
Targeting the PI3K/AKT/mTOR Signaling Pathway in Lung Cancer: An Update Regarding Potential Drugs and Natural Products	113
Current Status of Matrix-Assisted Laser Desorption/Ionization–Time-of-Flight Mass Spectrometry (MALDI-TOF MS) in Clinical Diagnostic Microbiology	113
Plant-Based Gums and Mucilages Applications in Pharmacology and Nanomedicine: A Review	111
Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance	110
Design of Photosensitizing Agents for Targeted Antimicrobial Photodynamic Therapy	110
The Concept of Folic Acid in Health and Disease	110