Genetics and Molecular Biology

Article	Citations
Zoonotic spillover: Understanding basic aspects for better prevention	80
Control and prevention of infectious diseases from a One Health perspective	46
Genome-wide analysis of the maize superoxide dismutase (SOD) gene family reveals important roles in drought and salt responses	23
Association of TYK2 polymorphisms with autoimmune diseases: A comprehensive and updated systematic review with meta-analysis	20
MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19	18
MicroRNA-149 is downregulated in Alzheimer’s disease and inhibits β-amyloid accumulation and ameliorates neuronal viability through targeting BACE1	16
Updated birth prevalence and relative frequency of mucopolysaccharidoses across Brazilian regions	15
EPO activates PI3K-IKKα-CDK1 signaling pathway to promote the proliferation of Glial Cells under hypoxia environment	14
Sending out an SOS - the bacterial DNA damage response	14
Applications of massively parallel sequencing in forensic genetics	13
Spontaneous chromosomal instability in peripheral blood lymphocytes from two molecularly confirmed Italian patients with Hereditary Fibrosis Poikiloderma: insights into cancer predisposition	11
Gene expression evaluation of antioxidant enzymes in patients with hepatocellular carcinoma: RT-qPCR and bioinformatic analyses	11
Telomere organization and the interstitial telomeric sites involvement in insects and vertebrates chromosome evolution	11
An immunogenetic view of COVID-19	10
Human DDX56 protein interacts with influenza A virus NS1 protein and stimulates the virus replication	10
Role of N6-methyl-adenosine modification in mammalian embryonic development	10
Molecular mechanisms and pharmacological interventions in the replication cycle of human coronaviruses	10
A novel PRRX1 loss-of-function variation contributing to familial atrial fibrillation and congenital patent ductus arteriosus	10
Expression of methyl farnesoate epoxidase (mfe) and juvenile hormone esterase (jhe) genes and their relation to social organization in the stingless bee Melipona interrupta (Hymenoptera: Apidae)	9
Evolutionary breakpoint regions and chromosomal remodeling in Harttia (Siluriformes: Loricariidae) species diversification	9
Resveratrol effects in bladder cancer: A mini review	9
Genomic analysis of Enterococcus durans LAB18S, a potential probiotic strain isolated from cheese	8
SARS-CoV-2 vaccine development and how Brazil is contributing	8
So alike yet so different. Differential expression of the long non-coding RNAs NORAD and HCG11 in breast cancer subtypes	8
Association between SNP rs527616 in lncRNA AQP4-AS1 and susceptibility to breast cancer in a southern Brazilian population	8

Evolutionary history of the SARS-CoV-2 Gamma variant of concern (P.1): a perfect storm	8
A novel mutation in ext2 caused hereditary multiple exostoses through reducing the synthesis of heparan sulfate	8
Genome sequencing and analysis of plant growth-promoting attributes from Leclercia adecarboxylata	8
Correlation between vaginal microbiota and different progression stages of cervical cancer	7
Periostin regulates osteogenesis of mesenchymal stem cells from ovariectomized rats through actions on the ILK/Akt/GSK-3β Axis	7
Exome sequencing and targeted gene panels: a simulated comparison of diagnostic yield using data from 158 patients with rare diseases	7
FOXE1 polymorphisms and chronic exposure to nitrates in drinking water cause metabolic dysfunction, thyroid abnormalities, and genotoxic damage in women	7
MiR-181b serves as diagnosis and prognosis biomarker in severe community-acquired pneumonia	7
The paradox of autophagy in Tuberous Sclerosis Complex	7
The evolution and function of the PSEUDO RESPONSE REGULATOR gene family in the plant circadian clock	7
Epigenetic alterations in canine mammary cancer	6
Molecular evolution and diversification of phytoene synthase (PSY) gene family	6
The use of adenoviral vectors in gene therapy and vaccine approaches	6
NDUFV1 mutations in complex I deficiency: Case reports and review of symptoms	6
Protection is not always a good thing: The immune system’s impact on gene therapy	6
A phylogenetic review of cancer resistance highlights evolutionary solutions to Peto’s Paradox	6
Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, and its population genetics caveats in Native Americans	6
Meiotic self-pairing of the Psalidodon (Characiformes, Characidae) iso-B chromosome: A successful perpetuation mechanism	6
Exosomes secreted from bone marrow mesenchymal stem cells suppress cardiomyocyte hypertrophy through Hippo-YAP pathway in heart failure	6
Chromosomal aberrations after induced pluripotent stem cells reprogramming	6
COVID-19 during pregnancy and adverse outcomes: Concerns and recommendations from The Brazilian Teratology Information Service	6
Molecular cytogenetic analysis and the establishment of a cell culture in the fish species Hollandichthys multifasciatus (Eigenmann & Norris, 1900) (Characiformes, Characidae)	6
Beyond transcription factors: more regulatory layers affecting soybean gene expression under abiotic stress	6
Expression profiling of some Acute Myeloid Leukemia - associated markers to assess their diagnostic / prognostic potential	5
Extreme phenotypes approach to investigate host genetics and COVID-19 outcomes	5
Identification of bZIP transcription factors and their responses to brown spot in pear	5
Integrated analysis of gene expression and DNA methylation datasets identified key genes and a 6-gene prognostic signature for primary lung adenocarcinoma	5
Palmitic acid decreases cell migration by increasing RGS2 expression and decreasing SERCA expression	5
miR-34a regulates phenotypic modulation of vascular smooth muscle cells in intracranial aneurysm by targeting CXCR3 and MMP-2	5
Long noncoding RNA POU6F2-AS1 regulates lung cancer aggressiveness through sponging miR-34c-5p to modulate KCNJ4 expression	5
Perspectives in Myrtaceae evolution from plastomes and nuclear phylogenies	5
Frequency of CFTR variants in southern Brazil and indication for modulators therapy in patients with cystic fibrosis	5
Protective role of exosomes derived from regulatory T cells against inflammation and apoptosis of BV-2 microglia under oxygen-glucose deprivation/reperfusion challenge	5
Association between folate metabolism polymorphisms and breast cancer: a case-control study	5
Genetic structure of the endangered Irrawaddy dolphin (Orcaella brevirostris) in the Gulf of Thailand	4
Overexpression of RAPGEF3 enhances the therapeutic effect of dezocine in treatment of neuropathic pain	4
Comparative and phylogenetic analyses of Swertia L. (Gentianaceae) medicinal plants (from Qinghai, China) based on complete chloroplast genomes	4
A new view on the scenario of karyotypic stasis in Epinephelidae fish: Cytogenetic, historical, and biogeographic approaches	4
Fantastic databases and where to find them: Web applications for researchers in a rush	4
Comparative cytogenetics among Boana species (Anura, Hylidae): focus on evolutionary variability of repetitive DNA	4
Genetic information improves the prediction of major adverse cardiovascular events in the GENEMACOR population	4
Association of PSORS1C3, CARD14 and TLR4 genotypes and haplotypes with psoriasis susceptibility	4
Human induced pluripotent stem cells as a tool for disease modeling and drug screening for COVID-19	4
Increased runs of homozygosity in the autosomal genome of Brazilian individuals with neurodevelopmental delay/intellectual disability and/or multiple congenital anomalies investigated by chromosomal m	4
FABP4 and omentin-1 gene expression in epicardial adipose tissue from coronary artery disease patients	4
Genome-wide, evolutionary, and functional analyses of ascorbate peroxidase (APX) family in Poaceae species	4
Enhanced expression of OsNAC5 leads to up-regulation of OsNAC6 and changes rice (Oryza sativa L.) ionome	4
The clinical significance and function of miR-146 in the promotion of epidural fibrosis	4
Comparative transcriptome analysis of different tissues of Rheum tanguticum Maxim. ex Balf. (Polygonaceae) reveals putative genes involved in anthraquinone biosynthesis	4
Resveratrol prevents inflammation and oxidative stress response in LPS-induced human gingival fibroblasts by targeting the PI3K/AKT and Wnt/β-catenin signaling pathways	4

Genome editing in maize: Toward improving complex traits in a global crop	4
An integrated approach to identify bimodal genes associated with prognosis in câncer	4
Mutations and insights into the molecular mechanisms of resistance of Mycobacterium tuberculosis to first-line	4
Transcribed Ultraconserved Regions: New regulators in cancer signaling and potential biomarkers	4
Genomic sequencing of different sequevars of Ralstonia solanacearum belonging to the Moko ecotype	4
Diversity of bacteriocins in the microbiome of the Tucuruí Hydroelectric Power Plant water reservoir and three-dimensional structure prediction of a zoocin	3
Ancient origin of Jingchuvirales derived glycoproteins integrated in arthropod genomes	3
Host-shift as the cause of emerging infectious diseases: Experimental approaches using Drosophila-virus interactions	3
Structural analysis of new compound heterozygous variants in PEPD gene identified in a patient with Prolidase Deficiency diagnosed by exome sequencing	3
Identification and characterization of repetitive DNA in the genus Didelphis Linnaeus, 1758 (Didelphimorphia, Didelphidae) and the use of satellite DNAs as phylogenetic markers	3
Investigation of changes in protein stability and substrate affinity of 3CL-protease of SARS-CoV-2 caused by mutations	3
Karyotype variability in six Amazonian species of the family Curimatidae (Characiformes) revealed by repetitive sequence mapping	3
The fructose-1,6-bisphosphatase deficiency and the p.(Lys204ArgfsTer72) variant	3
Analysis of renal lesions in Chinese tuberous sclerosis complex patients with different types of TSC gene mutations	3
Common BMI and diabetes-related genetic variants: A pilot study among indigenous people in the Brazilian Amazon	3
MT1G inhibits the growth and epithelial-mesenchymal transition of gastric cancer cells by regulating the PI3K/AKT signaling pathway	3
Fire ants: What do rural and urban areas show us about occurrence, diversity, and ancestral state reconstruction?	3
TMEM147 is a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma	3
The lncRNA MALAT1 is upregulated in urine of type 1 diabetes mellitus patients with diabetic kidney disease	3
Transcriptomic analysis reveals that mTOR pathway can be modulated in macrophage cells by the presence of cryptococcal cells	3
Analysis of potential virulence genes and competence to transformation in Haemophilus influenzae biotype aegyptius associated with Brazilian Purpuric Fever	3
Cryptic diversity and diversification processes in three cis-Andean Rhamdia species (Siluriformes: Heptapteridae) revealed by DNA barcoding	3
Multiple haplotypes of Chelonia mydas juveniles in a threatened hotspot area in Southern Brazil	3
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion	3
Orf165 is associated with cytoplasmic male sterility in pepper	3
RNP-world: The ultimate essence of life is a ribonucleoprotein process	3
Cytotaxonomy of Gallinula melanops (Gruiformes, Rallidae): Karyotype evolution and phylogenetic inference	3
Reconstruction of the Doradinae (Siluriformes-Doradidae) ancestral diploid number and NOR pattern reveals new insights about the karyotypic diversification of the Neotropical thorny catfishes	3
LINC00974 sponges miR-33a to facilitate cell proliferation, invasion, and EMT of ovarian cancer through HMGB2 upregulation	3
Basal levels of inorganic elements, genetic damages, and hematological values in captive Falco peregrinus	3
Molecular data reveal a complex population genetic structure for Psalidodon scabripinnis (Teleostei: Characidae) in the Atlantic Rainforest, Brazil	3
Genetic structure and diversity of the Chilean flat oyster Ostrea chilensis (Bivalvia: Ostreidae) along its natural distribution from natural beds subject to different fishing histories	2
Transcriptome analysis during fruit developmental stages in durian (Durio zibethinus Murr.) var. D24	2
SARS-CoV-2 and COVID-19: A perspective from environmental virology	2
DOF gene family expansion and diversification	2
The mitochondrial genome of Stereolepis doederleini (Pempheriformes: Polyprionidae) and mitogenomic phylogeny of Pempheriformes	2
DNA barcode reveals candidate species of Scinax and Ololygon (Anura: Hylidae) in Atlantic Forest	2
The past, present and future of genomics and bioinformatics: A survey of Brazilian scientists	2
High-quality genome assembly of Pseudocercospora ulei the main threat to natural rubber trees	2
EphA2 overexpression reduces H2O2-induced damage of lens epithelial cells	2
The good, the bad and the ugly of transposable elements annotation tools	2
Study of four Neotropical species of tree crickets Oecanthus Serville, 1831 (Orthoptera, Gryllidae) using cytogenetic and molecular markers	2
Characterization of the 3'UTR of the BTD gene and identification of regulatory elements and microRNAs	2
COVID-19 impact on the diagnosis of Inborn Errors of Metabolism: Data from a reference center in Brazil	2
Breast cancer-associated SNP rs72755295 is a cis-regulatory variation for human EXO1	2
Challenges in estimating virus divergence times in short epidemic timescales with special reference to the evolution of SARS-CoV-2 pandemic	2
APOE and KLF14 genetic variants are sex-specific for low high-density lipoprotein cholesterol identified by a genome-wide association study	2
Phylogeography and karyotypic evolution of some Deuterodon species from southeastern Brazil (Characiformes, Characidae, Stethaprioninae)	2
Neonatal screening for spinal muscular atrophy: A pilot study in Brazil	2
LncRNA AK001796 promotes cell proliferation via acting as a ceRNA of miR-150 in hepatocellular carcinoma	2
Investigating the evolutionary dynamics of diploid number variation in Ctenomys (Ctenomyidae, Rodentia)	2
Cytogenetic and molecular characteristics of Potamotrygon motoro and Potamotrygon sp. (Chondrichthyes, Myliobatiformes, Potamotrygonidae) from the Amazon basin: Implications for the taxonomy of the ge	2
Influence of hypoxia on biochemical aspects and on expression of genes related to oxygen-homeostasis of the Amazonian cichlid Astronotus ocellatus (Agassiz, 1831)	2
Interpopulation variation of transposable elements of the hAT superfamily in Drosophila willistoni (Diptera: Drosophilidae): in-situ approach	2
Integrated analysis of label-free quantitative proteomics and bioinformatics reveal insights into signaling pathways in male breast cancer	2
Circular RNA circENTPD7 suppresses the accumulation of PTEN to promote cell proliferation in non-small cell lung cancer	2
Clinical genomics and precision medicine	2
Sugarcane multitrophic interactions: Integrating belowground and aboveground organisms	2
Sex in protists: A new perspective on the reproduction mechanisms of trypanosomatids	2
Comparative genomics and phylogenomics of the Ralstonia solanacearum Moko ecotype and its symptomatological variants	2
Systematic analyses of a novel circRNA-related miRNAs prognostic signature for Cervical Cancer	2
Biomarker potential of the LEF1/TCF family members in breast cancer: Bioinformatic investigation on expression and clinical significance	2
The multiple roles of lipid metabolism in yeast physiology during beer fermentation	2
Molecular tools confirm natural Leishmania (Viannia) guyanensis/L. (V.) shawi hybrids causing cutaneous leishmaniasis in the Amazon region of Brazil	2
Chromosomal Radiation: A model to explain karyotypic diversity in cryptic species	2
Transcriptome analysis reveals gene expression changes of pigs infected with non-lethal African swine fever virus	2
Cytochrome b sequence of the Mazama americana jucunda Thomas, 1913 holotype reveals Mazama bororo Duarte, 1996 as its junior synonym	2
Low STR variability in the threatened marsh deer, Blastocerus dichotomus, detected through amplicon sequencing in non-invasive samples	2
Impact of maternal dietary counseling in the first year of life on DNA methylation in a cohort of children	2
Increased prevalence of the CVD-associated ANRIL allele in the Roma/Gypsy population in comparison with the majority Czech population	2
The rs1800469 T/T and rs1800470 C/C genotypes of the TGFB1 gene confer protection against diabetic retinopathy in a Southern Brazilian population	1
Telomere length in healthy newborns is not affected by adverse intrauterine environments	1
COVID-19: The question of genetic diversity and therapeutic intervention approaches	1
Genetic diversity of toxigenic Fusarium verticillioides associated with maize grains, India	1
Alpha thalassemia and alpha-MRE haplotypes in Uruguayan patients with microcytosis and hypochromia without anemia	1
Comparison of genotyping methods and toxin gene profiles of Staphylococcus aureus isolates from clinical specimens	1
In silico comparisons of lipid-related genes between Mycobacterium tuberculosis and BCG vaccine strains	1
Development and identification of an elite wheat-Hordeum californicum T6HcS/6BL translocation line ND646 containing several desirable traits	1
Karyotypic characterization of Centromochlus schultzi Rössel 1962 (Auchenipteridae, Centromochlinae) from the Xingu River basin: New inferences on chromosomal evolution in Centromochlus	1
The complete chloroplast genome sequence of Vincetoxicum mongolicum (Apocynaceae), a perennial medicinal herb	1

Emerging complexities and rising omission: Contrasts among socio-ecological contexts of infectious diseases, research and policy in Brazil	1
Gene structure of three kinds of vacuolar-type Na+/H+ antiporters including TaNHX2 transcribed in bread wheat	1
Influence of environmental dust in transformation capacity of Streptococcus pneumoniae	1
An efficient Agrobacterium tumefaciens-mediated transformation method for Simplicillium subtropicum (Hypocreales: Cordycipitaceae)	1
Investigating the shared genetic architecture between breast and ovarian cancers	1
Capra hircus outliers markers in Brazil: Searching for genomic regions under the action of natural selection	1
Breeding for reduced seed dormancy to domesticate new grass species	1
miR-140-3p suppresses the proliferation and migration of macrophages	1
Haplotypes of single cancer driver genes and their local ancestry in a highly admixed long-lived population of Northeast Brazil	1
Cytogenetic and genetic data support Crossodactylus aeneus Müller, 1924 as a new junior synonym of C. gaudichaudii Duméril and Bibron, 1841 (Amphibia, Anura)	1
Sampling strategies for sugarcane using either clonal replicates or diverse genotypes can bias the conclusions of RNA-Seq studies	1
Blood groups in Native Americans: a look beyond ABO and Rh	1
Haplotypes traceability and genetic variability of the breeding population of pacu (Piaractus mesopotamicus) revealed by mitochondrial DNA	1
Genome-wide identification and evolutionary view of ALOG gene family in Solanaceae	1
Optimization of cationic polymer-mediated transfection for RNA interference	1
Alterations of actin cytoskeleton and arterial protein level in patients with obstructive jaundice	1
Evolutionary and structural aspects of Solanaceae RNases T2	1
The complete plastid genome of Cotinus coggygria and phylogenetic analysis of the Anacardiaceae	1
Complete genome sequence of Bacillus thuringiensis BR145, a strain with insecticidal activity against Lepidoptera pests	1
Phenotypic and molecular basis for genetic variation in jelly palms (Butia sp.): where are we now and where are we headed to?	1
Wheat blast: The last enemy of hunger fighters	1
Shades of white: The Petunia long corolla tube clade evolutionary history	1
A genomic perspective on South American human history	1
Mitogenome of Coprophanaeus ensifer and phylogenetic analysis of the Scarabaeidae family (Coleoptera)	1
Chloroplast genome characteristics and phylogenetic analysis of the medicinal plant Blumea balsamifera (L.) DC	1
Establishment of rapid and non-invasive protocols to identify B-carrying individuals of Psalidodon paranae	1
Reduced gene flow and bottleneck in the threatened giant armadillo (Priodontes maximus): implications for its conservation	1
Adaptive strategies of aquatic mammals: Exploring the role of the HIF pathway and hypoxia tolerance	1
TLR4 and TLR8 variability in Amazonian and West Indian manatee species from Brazil	1
Enhancer in cancer pathogenesis and treatment	1
Group I introns: Structure, splicing and their applications in medical mycology	1
Insights into the evolutionary history of the most skilled tool-handling platyrrhini monkey: Sapajus libidinosus from the Serra da Capivara National Park	1
Transcriptional signature of host shift in the seed beetle Zabrotes subfasciatus	1
Reference genes for quantitative real-time PCR normalization of Cenostigma pyramidale roots under salt stress and mycorrhizal association	1
Vitamin D and estrogen steroid hormones and their immunogenetic roles in Infectious respiratory (TB and COVID-19) diseases	1
DNA repair-related genes and adipogenesis: Lessons from congenital lipodystrophies	1
Tailed bacteriophages (Caudoviricetes) dominate the microbiome of a diseased stingless bee	1