OOIR: Observatory of International Research

Papers

(The median citation count of Genetics and Molecular Biology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Zoonotic spillover: Understanding basic aspects for better prevention	59
Control and prevention of infectious diseases from a One Health perspective	35
MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19	16
Association of TYK2 polymorphisms with autoimmune diseases: A comprehensive and updated systematic review with meta-analysis	14
Genome-wide analysis of the maize superoxide dismutase (SOD) gene family reveals important roles in drought and salt responses	14
EPO activates PI3K-IKKα-CDK1 signaling pathway to promote the proliferation of Glial Cells under hypoxia environment	13
MicroRNA-149 is downregulated in Alzheimer’s disease and inhibits β-amyloid accumulation and ameliorates neuronal viability through targeting BACE1	12
Updated birth prevalence and relative frequency of mucopolysaccharidoses across Brazilian regions	12
Molecular mechanisms and pharmacological interventions in the replication cycle of human coronaviruses	10
An immunogenetic view of COVID-19	10
Spontaneous chromosomal instability in peripheral blood lymphocytes from two molecularly confirmed Italian patients with Hereditary Fibrosis Poikiloderma: insights into cancer predisposition	10
Gene expression evaluation of antioxidant enzymes in patients with hepatocellular carcinoma: RT-qPCR and bioinformatic analyses	9
Human DDX56 protein interacts with influenza A virus NS1 protein and stimulates the virus replication	9
Role of N6-methyl-adenosine modification in mammalian embryonic development	9
Resveratrol effects in bladder cancer: A mini review	9
Applications of massively parallel sequencing in forensic genetics	8
Sending out an SOS - the bacterial DNA damage response	8
Association between SNP rs527616 in lncRNA AQP4-AS1 and susceptibility to breast cancer in a southern Brazilian population	8
Genomic analysis of Enterococcus durans LAB18S, a potential probiotic strain isolated from cheese	8
Evolutionary history of the SARS-CoV-2 Gamma variant of concern (P.1): a perfect storm	8
A novel mutation in ext2 caused hereditary multiple exostoses through reducing the synthesis of heparan sulfate	7
Genome sequencing and analysis of plant growth-promoting attributes from Leclercia adecarboxylata	7
Telomere organization and the interstitial telomeric sites involvement in insects and vertebrates chromosome evolution	7
The paradox of autophagy in Tuberous Sclerosis Complex	7
SARS-CoV-2 vaccine development and how Brazil is contributing	7

A novel PRRX1 loss-of-function variation contributing to familial atrial fibrillation and congenital patent ductus arteriosus	7
Evolutionary breakpoint regions and chromosomal remodeling in Harttia (Siluriformes: Loricariidae) species diversification	6
So alike yet so different. Differential expression of the long non-coding RNAs NORAD and HCG11 in breast cancer subtypes	6
MiR-181b serves as diagnosis and prognosis biomarker in severe community-acquired pneumonia	6
Periostin regulates osteogenesis of mesenchymal stem cells from ovariectomized rats through actions on the ILK/Akt/GSK-3β Axis	5
Molecular cytogenetic analysis and the establishment of a cell culture in the fish species Hollandichthys multifasciatus (Eigenmann & Norris, 1900) (Characiformes, Characidae)	5
Extreme phenotypes approach to investigate host genetics and COVID-19 outcomes	5
FOXE1 polymorphisms and chronic exposure to nitrates in drinking water cause metabolic dysfunction, thyroid abnormalities, and genotoxic damage in women	5
Integrated analysis of gene expression and DNA methylation datasets identified key genes and a 6-gene prognostic signature for primary lung adenocarcinoma	5
Palmitic acid decreases cell migration by increasing RGS2 expression and decreasing SERCA expression	5
Identification of bZIP transcription factors and their responses to brown spot in pear	5
COVID-19 during pregnancy and adverse outcomes: Concerns and recommendations from The Brazilian Teratology Information Service	5
Expression of methyl farnesoate epoxidase (mfe) and juvenile hormone esterase (jhe) genes and their relation to social organization in the stingless bee Melipona interrupta (Hymenoptera: Apidae)	5
Perspectives in Myrtaceae evolution from plastomes and nuclear phylogenies	4
Genomic sequencing of different sequevars of Ralstonia solanacearum belonging to the Moko ecotype	4
Chromosomal aberrations after induced pluripotent stem cells reprogramming	4
Exome sequencing and targeted gene panels: a simulated comparison of diagnostic yield using data from 158 patients with rare diseases	4
A new view on the scenario of karyotypic stasis in Epinephelidae fish: Cytogenetic, historical, and biogeographic approaches	4
NDUFV1 mutations in complex I deficiency: Case reports and review of symptoms	4
Exosomes secreted from bone marrow mesenchymal stem cells suppress cardiomyocyte hypertrophy through Hippo-YAP pathway in heart failure	4
Epigenetic alterations in canine mammary cancer	4
Increased runs of homozygosity in the autosomal genome of Brazilian individuals with neurodevelopmental delay/intellectual disability and/or multiple congenital anomalies investigated by chromosomal m	4
Expression profiling of some Acute Myeloid Leukemia - associated markers to assess their diagnostic / prognostic potential	4
Resveratrol prevents inflammation and oxidative stress response in LPS-induced human gingival fibroblasts by targeting the PI3K/AKT and Wnt/β-catenin signaling pathways	4
miR-34a regulates phenotypic modulation of vascular smooth muscle cells in intracranial aneurysm by targeting CXCR3 and MMP-2	4
Association between folate metabolism polymorphisms and breast cancer: a case-control study	4
Identification and characterization of repetitive DNA in the genus Didelphis Linnaeus, 1758 (Didelphimorphia, Didelphidae) and the use of satellite DNAs as phylogenetic markers	3
Protective role of exosomes derived from regulatory T cells against inflammation and apoptosis of BV-2 microglia under oxygen-glucose deprivation/reperfusion challenge	3
Analysis of potential virulence genes and competence to transformation in Haemophilus influenzae biotype aegyptius associated with Brazilian Purpuric Fever	3
FABP4 and omentin-1 gene expression in epicardial adipose tissue from coronary artery disease patients	3
Diversity of bacteriocins in the microbiome of the Tucuruí Hydroelectric Power Plant water reservoir and three-dimensional structure prediction of a zoocin	3
Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, and its population genetics caveats in Native Americans	3
The use of adenoviral vectors in gene therapy and vaccine approaches	3
Meiotic self-pairing of the Psalidodon (Characiformes, Characidae) iso-B chromosome: A successful perpetuation mechanism	3
Frequency of CFTR variants in southern Brazil and indication for modulators therapy in patients with cystic fibrosis	3
Genetic structure of the endangered Irrawaddy dolphin (Orcaella brevirostris) in the Gulf of Thailand	3
Overexpression of RAPGEF3 enhances the therapeutic effect of dezocine in treatment of neuropathic pain	3
Comparative and phylogenetic analyses of Swertia L. (Gentianaceae) medicinal plants (from Qinghai, China) based on complete chloroplast genomes	3
An integrated approach to identify bimodal genes associated with prognosis in câncer	3
Cryptic diversity and diversification processes in three cis-Andean Rhamdia species (Siluriformes: Heptapteridae) revealed by DNA barcoding	3
Host-shift as the cause of emerging infectious diseases: Experimental approaches using Drosophila-virus interactions	3
Genetic information improves the prediction of major adverse cardiovascular events in the GENEMACOR population	3
Fire ants: What do rural and urban areas show us about occurrence, diversity, and ancestral state reconstruction?	3
TMEM147 is a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma	3
Cytotaxonomy of Gallinula melanops (Gruiformes, Rallidae): Karyotype evolution and phylogenetic inference	3
Beyond transcription factors: more regulatory layers affecting soybean gene expression under abiotic stress	3
Long noncoding RNA POU6F2-AS1 regulates lung cancer aggressiveness through sponging miR-34c-5p to modulate KCNJ4 expression	3
A phylogenetic review of cancer resistance highlights evolutionary solutions to Peto’s Paradox	3
Analysis of renal lesions in Chinese tuberous sclerosis complex patients with different types of TSC gene mutations	3
The clinical significance and function of miR-146 in the promotion of epidural fibrosis	3

MT1G inhibits the growth and epithelial-mesenchymal transition of gastric cancer cells by regulating the PI3K/AKT signaling pathway	3
Comparative transcriptome analysis of different tissues of Rheum tanguticum Maxim. ex Balf. (Polygonaceae) reveals putative genes involved in anthraquinone biosynthesis	3
Molecular data reveal a complex population genetic structure for Psalidodon scabripinnis (Teleostei: Characidae) in the Atlantic Rainforest, Brazil	2
Molecular evolution and diversification of phytoene synthase (PSY) gene family	2
COVID-19 impact on the diagnosis of Inborn Errors of Metabolism: Data from a reference center in Brazil	2
Comparative cytogenetics among Boana species (Anura, Hylidae): focus on evolutionary variability of repetitive DNA	2
The mitochondrial genome of Stereolepis doederleini (Pempheriformes: Polyprionidae) and mitogenomic phylogeny of Pempheriformes	2
Breast cancer-associated SNP rs72755295 is a cis-regulatory variation for human EXO1	2
Karyotype variability in six Amazonian species of the family Curimatidae (Characiformes) revealed by repetitive sequence mapping	2
Transcriptomic analysis reveals that mTOR pathway can be modulated in macrophage cells by the presence of cryptococcal cells	2
APOE and KLF14 genetic variants are sex-specific for low high-density lipoprotein cholesterol identified by a genome-wide association study	2
SARS-CoV-2 and COVID-19: A perspective from environmental virology	2
Fantastic databases and where to find them: Web applications for researchers in a rush	2
EphA2 overexpression reduces H2O2-induced damage of lens epithelial cells	2
Transcriptome analysis during fruit developmental stages in durian (Durio zibethinus Murr.) var. D24	2
Human induced pluripotent stem cells as a tool for disease modeling and drug screening for COVID-19	2
Challenges in estimating virus divergence times in short epidemic timescales with special reference to the evolution of SARS-CoV-2 pandemic	2
Protection is not always a good thing: The immune system’s impact on gene therapy	2
Systematic analyses of a novel circRNA-related miRNAs prognostic signature for Cervical Cancer	2
The evolution and function of the PSEUDO RESPONSE REGULATOR gene family in the plant circadian clock	2
Characterization of the 3'UTR of the BTD gene and identification of regulatory elements and microRNAs	2
Structural analysis of new compound heterozygous variants in PEPD gene identified in a patient with Prolidase Deficiency diagnosed by exome sequencing	2
Orf165 is associated with cytoplasmic male sterility in pepper	2
Mutations and insights into the molecular mechanisms of resistance of Mycobacterium tuberculosis to first-line	2
The fructose-1,6-bisphosphatase deficiency and the p.(Lys204ArgfsTer72) variant	2
Enhanced expression of OsNAC5 leads to up-regulation of OsNAC6 and changes rice (Oryza sativa L.) ionome	2
The past, present and future of genomics and bioinformatics: A survey of Brazilian scientists	2
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion	2
Investigation of changes in protein stability and substrate affinity of 3CL-protease of SARS-CoV-2 caused by mutations	2
LINC00974 sponges miR-33a to facilitate cell proliferation, invasion, and EMT of ovarian cancer through HMGB2 upregulation	2
Transcribed Ultraconserved Regions: New regulators in cancer signaling and potential biomarkers	2
Clinical genomics and precision medicine	2
Correlation between vaginal microbiota and different progression stages of cervical cancer	2
DNA barcode reveals candidate species of Scinax and Ololygon (Anura: Hylidae) in Atlantic Forest	2
Development and identification of an elite wheat-Hordeum californicum T6HcS/6BL translocation line ND646 containing several desirable traits	1
The complete plastid genome of Cotinus coggygria and phylogenetic analysis of the Anacardiaceae	1
Association of PSORS1C3, CARD14 and TLR4 genotypes and haplotypes with psoriasis susceptibility	1
COVID-19: The question of genetic diversity and therapeutic intervention approaches	1
miR-140-3p suppresses the proliferation and migration of macrophages	1
The lncRNA MALAT1 is upregulated in urine of type 1 diabetes mellitus patients with diabetic kidney disease	1
Blood groups in Native Americans: a look beyond ABO and Rh	1
Haplotypes of single cancer driver genes and their local ancestry in a highly admixed long-lived population of Northeast Brazil	1
Integrated analysis of label-free quantitative proteomics and bioinformatics reveal insights into signaling pathways in male breast cancer	1
Circular RNA circENTPD7 suppresses the accumulation of PTEN to promote cell proliferation in non-small cell lung cancer	1
Reference genes for quantitative real-time PCR normalization of Cenostigma pyramidale roots under salt stress and mycorrhizal association	1
Increased prevalence of the CVD-associated ANRIL allele in the Roma/Gypsy population in comparison with the majority Czech population	1
Cytochrome b sequence of the Mazama americana jucunda Thomas, 1913 holotype reveals Mazama bororo Duarte, 1996 as its junior synonym	1
Common BMI and diabetes-related genetic variants: A pilot study among indigenous people in the Brazilian Amazon	1
Influence of environmental dust in transformation capacity of Streptococcus pneumoniae	1
TLR4 and TLR8 variability in Amazonian and West Indian manatee species from Brazil	1
Haplotypes traceability and genetic variability of the breeding population of pacu (Piaractus mesopotamicus) revealed by mitochondrial DNA	1
DNA repair-related genes and adipogenesis: Lessons from congenital lipodystrophies	1
Mitogenome of Coprophanaeus ensifer and phylogenetic analysis of the Scarabaeidae family (Coleoptera)	1
Molecular tools confirm natural Leishmania (Viannia) guyanensis/L. (V.) shawi hybrids causing cutaneous leishmaniasis in the Amazon region of Brazil	1
In silico comparisons of lipid-related genes between Mycobacterium tuberculosis and BCG vaccine strains	1
A genomic perspective on South American human history	1
Establishment of rapid and non-invasive protocols to identify B-carrying individuals of Psalidodon paranae	1
Multiple haplotypes of Chelonia mydas juveniles in a threatened hotspot area in Southern Brazil	1
Evolutionary and structural aspects of Solanaceae RNases T2	1
Cytogenetic and molecular characteristics of Potamotrygon motoro and Potamotrygon sp. (Chondrichthyes, Myliobatiformes, Potamotrygonidae) from the Amazon basin: Implications for the taxonomy of the ge	1
Complete genome sequence of Bacillus thuringiensis BR145, a strain with insecticidal activity against Lepidoptera pests	1
Genome-wide, evolutionary, and functional analyses of ascorbate peroxidase (APX) family in Poaceae species	1
High-quality genome assembly of Pseudocercospora ulei the main threat to natural rubber trees	1
Sugarcane multitrophic interactions: Integrating belowground and aboveground organisms	1
Gene structure of three kinds of vacuolar-type Na+/H+ antiporters including TaNHX2 transcribed in bread wheat	1
Optimization of cationic polymer-mediated transfection for RNA interference	1
An efficient Agrobacterium tumefaciens-mediated transformation method for Simplicillium subtropicum (Hypocreales: Cordycipitaceae)	1
RNP-world: The ultimate essence of life is a ribonucleoprotein process	1
Phylogeography and karyotypic evolution of some Deuterodon species from southeastern Brazil (Characiformes, Characidae, Stethaprioninae)	1
Cytogenetic and genetic data support Crossodactylus aeneus Müller, 1924 as a new junior synonym of C. gaudichaudii Duméril and Bibron, 1841 (Amphibia, Anura)	1
Investigating the evolutionary dynamics of diploid number variation in Ctenomys (Ctenomyidae, Rodentia)	1
Low STR variability in the threatened marsh deer, Blastocerus dichotomus, detected through amplicon sequencing in non-invasive samples	1
Genome editing in maize: Toward improving complex traits in a global crop	1
Gene Expression Analysis Platform (GEAP): A highly customizable, fast, versatile and ready-to-use microarray analysis platform	1
The complete chloroplast genome sequence of Vincetoxicum mongolicum (Apocynaceae), a perennial medicinal herb	1
Chloroplast genome characteristics and phylogenetic analysis of the medicinal plant Blumea balsamifera (L.) DC	1
Basal levels of inorganic elements, genetic damages, and hematological values in captive Falco peregrinus	1
Ancient origin of Jingchuvirales derived glycoproteins integrated in arthropod genomes	1
Influence of hypoxia on biochemical aspects and on expression of genes related to oxygen-homeostasis of the Amazonian cichlid Astronotus ocellatus (Agassiz, 1831)	1