Mini-Reviews in Medicinal Chemistry

Papers
(The TQCC of Mini-Reviews in Medicinal Chemistry is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
A Review on Chemical Structures and Biological Activities of Dopamine Derivatives from Medicinal Insects86
Comprehensive Update on Synthetic Aspects of Bosentan Derivatives55
Aptamers Against COVID-19: An Untested Opportunity52
Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects49
Synthetic Approach to Potential Anticancer Benzimidazole Derivatives: A Review48
An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus46
Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes45
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease44
Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease42
Synthesis of Phenothiazine Derivatives and their Diverse Biological Activities: A Review41
Current Perspective of Synthesis of Medicinally Relevant Benzothiazole based Molecules: Potential for Antimicrobial and Anti-Inflammatory Activities41
The Role of IL-6 Released During Exercise to Insulin Sensitivity and Muscle Hypertrophy40
Targeting Lysosomes: A Strategy Against Chemoresistance in Cancer39
Quinoxaline: A Chemical Moiety with Spectrum of Interesting Biological Activities31
Meet the Editorial Board Member30
Meet the Editorial Board Member30
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Meet the Editorial Board Member29
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and Chemical Synthesis Approach28
The most Recent Compilation of Reactions of Enaminone Derivatives with various Amine Derivatives to Generate Biologically Active Compounds28
Chemotherapeutic Strategies for Combating Staphylococcus aureus Infections28
KRAS Pathway-based Therapeutic Approaches in Pancreatic Cancer28
Bioactive Sulfonamides Derived from Amino Acids: Their Synthesis and Pharmacological Activities28
Advances in Exercise Therapy in Hemodialysis: A Systematic Review26
Regulatory T Cells: Subtle and Promising Achilles' Heel of Psoriasis - Atherosclerosis Comorbidity26
Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome25
Revolutionizing Playing with Skeleton Atoms: Molecular Editing Surgery in Medicinal Chemistry24
Molecular Insights on the Therapeutic Effect of Selected Flavonoids on Diabetic Neuropathy23
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells23
Associate Editorial Board Members23
Meet the Editorial Board Member23
Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin’s Lymphoma22
Research Progress in Alpha-fetoprotein-induced Immunosuppression of Liver Cancer22
The Pivotal Function of SLC16A1 and SLC16A1-AS1 in Cancer Progress: Molecular Pathogenesis and Prognosis21
A Review on Acridines as Antiproliferative Agents21
Meet the Section Editor20
Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives20
Cinnamic Acid Derivatives: Recent Discoveries and Development Strategies for Alzheimer’s Disease20
Inhibitors of Epigenetic Modulators as Therapeutic Alternatives for Cardiovascular Diseases20
Natural Products with BACE1 and GSK3β Inhibitory Activity20
Overview of Piperine: Bioactivities, Total Synthesis, Structural Modification, and Structure-Activity Relationships20
Role of TBK1 Inhibition in Targeted Therapy of Cancer20
Pharmacological Efficacy and Safety of Glycyrrhiza glabra in the Treatment of Respiratory Tract Infections19
Recent Advancements in Strategies for Abnormal Protein Clearance in Alzheimer's Disease19
Meet the Frontiers Section Editor19
The Role of MiR-29 in the Mechanism of Fibrosis19
Medicinal Plants in Cancer Treatment: Contribution of Nuclear Factor- Kappa B (NF-kB) Inhibitors19
Meet the Editorial Board Member18
Meet the Editorial Board Member18
Roles of Accelerated Molecular Dynamics Simulations in Predictions of Binding Kinetic Parameters17
Breaking Barriers in Breast Cancer: Multi-Targeted Therapeutic Insights17
AGAP2-AS1: An Indispensable lncRNA in Tumors17
Drug Solubilization by Surfactants: Experimental Methods and Theoretical Perspectives17
Recent Literature on the Synthesis of Thiazole Derivatives and their Biological Activities16
Carbohydrazide Analogues: A Review of Synthesis and Biological Activities16
Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings16
Physicochemical Properties, Drug Delivery, and Tissue Engineering Applications of Neem Gum and Its Derivatives: A Comprehensive Review16
Nimbolide: A Potential Phytochemical Agent in Multimodal Pancreatic Cancer Therapies15
Meet the Editorial Board Member15
Quinoline Derivatives as Promising Scaffolds for Antitubercular Activity: A Comprehensive Review15
Drug Repurposing: A Conduit to Unravelling Metabolic Reprogramming for Cancer Treatment15
Recent Advances in the Development of Type 2 Sodium-Glucose Cotransporter Inhibitors for the Treatment of Type 2 Diabetes Mellitus15
Current Status of and Perspectives on Radiolabelled Ubiquicidin 29-41 Derivatives for Bacterial Infection Imaging15
N-Methyl-D-Aspartate (NMDA)-Type Glutamate Receptors and Demyelinating Disorders: A Neuroimmune Perspective14
Quinoxaline 1,4-di-N-Oxide Derivatives: Are They Unselective or Selective Inhibitors?14
Flavonoid-metal ion Complexes as Potent Anticancer Metallodrugs: A Comprehensive Review14
The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease14
Homometallic Polynuclear Rhodium Complexes in Anticancer Drug Development14
Development of Mycobacterium tuberculosis Enoyl Acyl Reductase (InhA) Inhibitors: A Mini-Review14
MicroRNAs and Efferocytosis: Implications for Diagnosis and Therapy14
Natural Products, Synthesis, and Biological Activities of Quinolines (2020-2024)14
The Art and Science of Antidiabetic Medications and Obesity Management14
The Effects of Increased Glucose Level and Glycolysis on SARS CoV-2 Infection14
An Overview of Pyridazinone Analogs: Chemical and Pharmacological Potential13
Meet the Editor-in-Chief13
Chemical Strategies Toward Prodrugs and Fluorescent Probes for Gasotransmitters13
Strategies in Taxol Development: A Review13
Comprehensive Insight into Green Synthesis Approaches, Structural Activity Relationship, and Therapeutic Potential of Pyrazolic Chalcone Derivative13
A Comprehensive Review on Chemistry and Biology of Tafamidis in Transthyretin Amyloidosis13
Meet the Editorial Board Member13
Meet the Editorial Board Member13
The Complex Roles of DNA Repair Pathways, Inhibitors, Hyperthermia, and Contact Inhibition in Cell Cycle Halts13
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Meet the Editorial Board Member13
Inhibitors Targeting Hepatitis C Virus (HCV) Entry13
Therapeutic Potentials of Aconite-like Alkaloids: Bioinformatics and Experimental Approaches12
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The Search for Antidotes Against Ricin12
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Second-line Therapy for Helicobacter Pylori Eradication: State of the Art12
Energy Metabolism Behavior and Response to Microenvironmental Factors of the Experimental Cancer Cell Models Differ from that of Actual Human Tumors12
Effects of Urtica dioica on Metabolic Profiles in Type 2 Diabetes: A Systematic Review and Meta-analysis of Clinical Trials12
Therapeutic Approaches for the Treatment of Interstitial Lung Disease: An Exploratory Review on Molecular Mechanisms12
Meet the Editorial Board Member12
A Critical Observation on the Design and Development of Reported Peptide Inhibitors of DENV NS2B-NS3 Protease in the Last Two Decades12
Chemistry, Analysis, and Biological Aspects of Daprodustat, A New Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor: A Comprehensive Review12
Recent Updates on Sinularia Soft Coral12
Meet the Editorial Board Member12
Radical Releasing Anti-tuberculosis Agents and the Treatment of Mycobacterial Tuberculosis Infections - An Overview12
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics12
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review12
The Situation of Small Molecules Targeting Key Proteins in combatting SARS-CoV-2: Synthesis, Metabolic Pathway, Mechanism of Action, and Potential Therapeutic Applications12
Nuclei-targeted Therapeutic Delivery: A Novel Concept for the Treatment of Cancer11
The Application of the Pyrazole Structure in the Structural Modification of Natural Products11
The Therapeutic Potential and Molecular Mechanisms Underlying the Neuroprotective Effects of Sativex® - A Cannabis-derived Spray11
Recent Insights of Metformin on Hepatocellular Carcinoma (HCC)11
Anthriscus sylvestris: An overview on Bioactive Compounds and Anticancer Mechanisms from a Traditional Medicinal Plant to Modern Investigation11
In vivo Pharmacokinetic and ADMET Profiles of Synthetic Antimicrobial Peptides (AMPs)11
Melatonin and Related Compounds as Antioxidants11
Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry11
New Insights into the Modifications and Bioactivities of Indole-3- Carboxaldehyde and its Derivatives as a Potential Scaffold for Drug Design: A Mini-Review11
The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)11
Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions11
A Therapeutic Journey of Potential Drugs Against COVID-1911
Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review11
Narrative Review of the Pharmacodynamics, Pharmacokinetics, and Toxicities of Illicit Synthetic Cannabinoid Receptor Agonists11
Antioxidant Activity of 1,2,4-Triazole and its Derivatives: A Mini-Review11
Modulation of Long Non-coding RNAs by Different Classes of Secondary Metabolites from Plants: A Mini-review on Antitumor Effects10
Acknowledgements to Reviewers10
Evaluation of Melatonin and its Nanostructures Effects on Skin Disorders Focused on Wound Healing10
Nicotinamide Adenine Dinucleotide in the Development and Treatment of Cardiac Remodeling and Aging10
Synthesis and Biological Properties of Isatin-indole Hybrids: A Review10
Chromone, A Privileged Scaffold in Drug Discovery: Developments in the Synthesis and Bioactivity10
Advances in Biocatalytic Synthesis, Pharmacological Activities, Pharmaceutical Preparation and Metabolism of Ginsenoside Rh210
Anticancer Potential of Naringenin, Biosynthesis, Molecular Target, and Structural Perspectives10
Meet the Editorial Board Member10
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases10
Aloe-emodin: Progress in Pharmacological Activity, Safety, and Pharmaceutical Formulation Applications10
Peroxisome Proliferator-activated Receptor-γ As A Novel and Promising Target For Treating Cancer Via Regulation of Inflammation: A Brief Review10
Research Progress in Mutagenesis Techniques for Aspergillus fumigatus and the Biological Activities of Fumagillin10
Some Scaffolds as Anti-leishmanial Agents: A Review10
Protective Effect of Plumeria Pudica Latex Proteins on Intestinal Mucositis Induced by 5-Fluorouracil10
Recent Advancements and SAR Studies of Synthetic Coumarins as MAO-B Inhibitors: An Updated Review10
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications10
Cardiovascular Effects of Ruthenium Complexes: A Potential Therapeutic Tool in Hypertension and Myocardial Injury10
Recent Development of CXCR4-Targeted Nuclear Medicine Research in Adrenocortical Tumors10
Agent in Urgent Need of Clinical Practice: Corilagin10
Meet the Editorial Board Member9
Pharmacological Modulation of Apoptosis and Autophagy in Pancreatic Cancer Treatment9
Systematic Review of the Serotonergic System in the Pathophysiology of Severe Dengue: The Theory of Thrombocytopenia and Vascular Extravasation9
MCM3AP-AS1: A LncRNA Participating in the Tumorigenesis of Cancer Through Multiple Pathways9
LncRNA DSCAM-AS1: A Pivotal Therapeutic Target in Cancer9
Targeting Bcl-2 with Indole Scaffolds: Emerging Drug Design Strategies for Cancer Treatment9
A Short Review on Glucogallin and its Pharmacological Activities9
The Indispensable Roles of GMDS and GMDS-AS1 in the Advancement of Cancer: Fucosylation, Signal Pathway and Molecular Pathogenesis9
Levothyroxine and Non-alcoholic Fatty Liver Disease: A Mini Review9
Fungal Endophytes: A Storehouse of Bioactive Compounds9
The Use of Nanocarriers to Enhance the Anti-neuroinflammatory Potential of Dietary Flavonoids in Animal Models of Neurodegenerative Diseases: A Systematic Review9
Recent Advances in Small Molecular PET Tracers for Pancreatic Cancer Diagnosis: Preclinical Stage9
Meet the Editorial Board Member9
Meet the Editor in Chief9
Natural and Synthetic Phosphodiesterase Inhibitors in 2023: an Update on the Impact on Neurological and Psychiatric Conditions9
Elucidating the Drug Repurposing Spectra of COVID-19 with its Analogues SARS and MERS9
Bioactivities of Dietary Polyphenols and Their Effects on Intestinal Microbiota9
Biological Activities of Morita-Baylis-Hillman Adducts (MBHA)9
Recent Studies on the Pharmacological Activities and Structural Modifications of Compound-K9
Meet the Co-Editor9
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