Mini-Reviews in Medicinal Chemistry

Papers
(The TQCC of Mini-Reviews in Medicinal Chemistry is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
A Review on Chemical Structures and Biological Activities of Dopamine Derivatives from Medicinal Insects61
Comprehensive Update on Synthetic Aspects of Bosentan Derivatives54
An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus52
Aptamers Against COVID-19: An Untested Opportunity51
Synthesis of Phenothiazine Derivatives and their Diverse Biological Activities: A Review50
Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease49
Synthetic Approach to Potential Anticancer Benzimidazole Derivatives: A Review47
Current Perspective of Synthesis of Medicinally Relevant Benzothiazole based Molecules: Potential for Antimicrobial and Anti-Inflammatory Activities39
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease38
Targeting Lysosomes: A Strategy Against Chemoresistance in Cancer38
The Role of IL-6 Released During Exercise to Insulin Sensitivity and Muscle Hypertrophy35
Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects35
Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes34
Antisense Molecules: Design, Chemistry, and Therapeutic Innovations34
Meet the Editorial Board Member33
Meet the Editorial Board Member32
Meet the Editorial Board Member32
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells30
Meet the Editorial Board Member29
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and Chemical Synthesis Approach28
KRAS Pathway-based Therapeutic Approaches in Pancreatic Cancer27
Advances in Exercise Therapy in Hemodialysis: A Systematic Review27
Bioactive Sulfonamides Derived from Amino Acids: Their Synthesis and Pharmacological Activities27
Regulatory T Cells: Subtle and Promising Achilles' Heel of Psoriasis - Atherosclerosis Comorbidity26
The most Recent Compilation of Reactions of Enaminone Derivatives with various Amine Derivatives to Generate Biologically Active Compounds25
Revolutionizing Playing with Skeleton Atoms: Molecular Editing Surgery in Medicinal Chemistry25
Associate Editorial Board Members25
Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome25
Overview of Piperine: Bioactivities, Total Synthesis, Structural Modification, and Structure-Activity Relationships24
Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin’s Lymphoma24
Role of TBK1 Inhibition in Targeted Therapy of Cancer24
A Review on Acridines as Antiproliferative Agents24
Recent Advancements in Strategies for Abnormal Protein Clearance in Alzheimer's Disease24
Inhibitors of Epigenetic Modulators as Therapeutic Alternatives for Cardiovascular Diseases23
Meet the Section Editor23
Cinnamic Acid Derivatives: Recent Discoveries and Development Strategies for Alzheimer’s Disease23
The Pivotal Function of SLC16A1 and SLC16A1-AS1 in Cancer Progress: Molecular Pathogenesis and Prognosis23
A Review of the Role of Poly (ADP-Ribose) Polymerase-1 (PARP1) and Its Inhibitors for Cancer Therapy22
Psilocybin: Chemical Foundations and Emerging Therapeutic Potential21
Molecular Insights on the Therapeutic Effect of Selected Flavonoids on Diabetic Neuropathy21
Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives21
Research Progress in Alpha-fetoprotein-induced Immunosuppression of Liver Cancer21
Medicinal Plants in Cancer Treatment: Contribution of Nuclear Factor- Kappa B (NF-kB) Inhibitors20
Pharmacological Efficacy and Safety of Glycyrrhiza glabra in the Treatment of Respiratory Tract Infections20
The Role of MiR-29 in the Mechanism of Fibrosis19
Natural Products with BACE1 and GSK3β Inhibitory Activity19
AGAP2-AS1: An Indispensable lncRNA in Tumors19
Meet the Frontiers Section Editor19
Meet the Editorial Board Member19
Breaking Barriers in Breast Cancer: Multi-Targeted Therapeutic Insights18
Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings18
Physicochemical Properties, Drug Delivery, and Tissue Engineering Applications of Neem Gum and Its Derivatives: A Comprehensive Review17
Marine-Derived Fucoidan in Cancer Therapy: Mechanistic Insights, Clinical Prospects, and Future Directions17
Research Hotspots and Trends of Artificial Intelligence in Drug Discovery: A Review and Bibliometric Analysis17
Natural Products as Autophagy-related Protein Kinase Inhibitors: A Future Promising Anticancer from Nature17
Critical Relationship Between Iron Deficiency Anaemia (IDA) and Glycated Haemoglobin (HbA1c): An Updated Review17
Roles of Accelerated Molecular Dynamics Simulations in Predictions of Binding Kinetic Parameters16
The Effects of Increased Glucose Level and Glycolysis on SARS CoV-2 Infection16
Meet the Editorial Board Member16
Recent Literature on the Synthesis of Thiazole Derivatives and their Biological Activities16
The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease16
Quinoline Derivatives as Promising Scaffolds for Antitubercular Activity: A Comprehensive Review16
Green-synthesized titanium dioxide nanoparticles: systematic review of antimicrobial efficacy and biocompatibility16
Current Status of and Perspectives on Radiolabelled Ubiquicidin 29-41 Derivatives for Bacterial Infection Imaging16
N-Methyl-D-Aspartate (NMDA)-Type Glutamate Receptors and Demyelinating Disorders: A Neuroimmune Perspective15
Drug Repurposing: A Conduit to Unravelling Metabolic Reprogramming for Cancer Treatment15
Natural Products, Synthesis, and Biological Activities of Quinolines (2020-2024)15
Nimbolide: A Potential Phytochemical Agent in Multimodal Pancreatic Cancer Therapies15
Innovative Approaches to Alzheimer's Treatment: Utilizing Tacrine Hybrids to Inhibit Amyloid Beta Aggregation as a Strategic Focus15
MicroRNAs and Efferocytosis: Implications for Diagnosis and Therapy15
Development of Mycobacterium tuberculosis Enoyl Acyl Reductase (InhA) Inhibitors: A Mini-Review15
Meet the Editorial Board Member15
Homometallic Polynuclear Rhodium Complexes in Anticancer Drug Development15
The Art and Science of Antidiabetic Medications and Obesity Management15
Flavonoid-metal ion Complexes as Potent Anticancer Metallodrugs: A Comprehensive Review15
Development of Triazole based Anticonvulsants through Various Catalytic Approaches15
Meet the Editorial Board Member14
A Comprehensive Review on Chemistry and Biology of Tafamidis in Transthyretin Amyloidosis14
The Complex Roles of DNA Repair Pathways, Inhibitors, Hyperthermia, and Contact Inhibition in Cell Cycle Halts14
Therapeutic Potentials of Aconite-like Alkaloids: Bioinformatics and Experimental Approaches14
Strategies in Taxol Development: A Review14
Meet the Editor-in-Chief14
Comprehensive Insight into Green Synthesis Approaches, Structural Activity Relationship, and Therapeutic Potential of Pyrazolic Chalcone Derivative14
Recent Updates on Sinularia Soft Coral14
Meet the Editorial Board Member14
Chemical Strategies Toward Prodrugs and Fluorescent Probes for Gasotransmitters14
Potential of Small Molecule TAAR-1 Agonists for the Therapy of Neurodegenerative Psychosis: A Medicinal Chemistry Perspective14
Inhibitors Targeting Hepatitis C Virus (HCV) Entry14
Meet the Editorial Board Member14
Meet the Editorial Board Member13
Meet the Editorial Board Member13
Meet the Editorial Board Member13
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics13
An Overview of Pyridazinone Analogs: Chemical and Pharmacological Potential13
A Critical Observation on the Design and Development of Reported Peptide Inhibitors of DENV NS2B-NS3 Protease in the Last Two Decades13
Meet the Editorial Board Member13
Melatonin and Related Compounds as Antioxidants12
Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review12
Therapeutic Approaches for the Treatment of Interstitial Lung Disease: An Exploratory Review on Molecular Mechanisms12
The Application of the Pyrazole Structure in the Structural Modification of Natural Products12
Energy Metabolism Behavior and Response to Microenvironmental Factors of the Experimental Cancer Cell Models Differ from that of Actual Human Tumors12
The Therapeutic Potential and Molecular Mechanisms Underlying the Neuroprotective Effects of Sativex® - A Cannabis-derived Spray12
The Search for Antidotes Against Ricin12
Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions12
Second-line Therapy for Helicobacter Pylori Eradication: State of the Art12
Nuclei-targeted Therapeutic Delivery: A Novel Concept for the Treatment of Cancer12
In vivo Pharmacokinetic and ADMET Profiles of Synthetic Antimicrobial Peptides (AMPs)12
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review12
Evaluation of Melatonin and its Nanostructures Effects on Skin Disorders Focused on Wound Healing12
Chemistry, Analysis, and Biological Aspects of Daprodustat, A New Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor: A Comprehensive Review12
A Therapeutic Journey of Potential Drugs Against COVID-1912
Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry11
The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)11
Recent Advancements and SAR Studies of Synthetic Coumarins as MAO-B Inhibitors: An Updated Review11
Research Progress in Mutagenesis Techniques for Aspergillus fumigatus and the Biological Activities of Fumagillin11
Narrative Review of the Pharmacodynamics, Pharmacokinetics, and Toxicities of Illicit Synthetic Cannabinoid Receptor Agonists11
New Insights into the Modifications and Bioactivities of Indole-3- Carboxaldehyde and its Derivatives as a Potential Scaffold for Drug Design: A Mini-Review11
Recent Insights of Metformin on Hepatocellular Carcinoma (HCC)11
Meet the Editorial Board Member11
Cardiovascular Effects of Ruthenium Complexes: A Potential Therapeutic Tool in Hypertension and Myocardial Injury11
Anthriscus sylvestris: An overview on Bioactive Compounds and Anticancer Mechanisms from a Traditional Medicinal Plant to Modern Investigation11
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications11
Aloe-emodin: Progress in Pharmacological Activity, Safety, and Pharmaceutical Formulation Applications11
Protective Effect of Plumeria Pudica Latex Proteins on Intestinal Mucositis Induced by 5-Fluorouracil11
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases11
Modulation of Long Non-coding RNAs by Different Classes of Secondary Metabolites from Plants: A Mini-review on Antitumor Effects10
Recent Development of CXCR4-Targeted Nuclear Medicine Research in Adrenocortical Tumors10
Meet the Co-Editor10
Agent in Urgent Need of Clinical Practice: Corilagin10
Targeting Bcl-2 with Indole Scaffolds: Emerging Drug Design Strategies for Cancer Treatment10
Synthesis and Biological Properties of Isatin-indole Hybrids: A Review10
Meet the Editor in Chief10
Nicotinamide Adenine Dinucleotide in the Development and Treatment of Cardiac Remodeling and Aging10
A Short Review on Glucogallin and its Pharmacological Activities10
Meet the Editorial Board Member10
Meet the Editorial Board Member10
Natural and Synthetic Phosphodiesterase Inhibitors in 2023: an Update on the Impact on Neurological and Psychiatric Conditions9
Recent Advances in Small Molecular PET Tracers for Pancreatic Cancer Diagnosis: Preclinical Stage9
MCM3AP-AS1: A LncRNA Participating in the Tumorigenesis of Cancer Through Multiple Pathways9
Natural Product-based Therapies for Inflammatory Bowel Disease: Targeting Key Signaling Pathways9
Pharmacological Modulation of Apoptosis and Autophagy in Pancreatic Cancer Treatment9
The Use of Nanocarriers to Enhance the Anti-neuroinflammatory Potential of Dietary Flavonoids in Animal Models of Neurodegenerative Diseases: A Systematic Review9
Fungal Endophytes: A Storehouse of Bioactive Compounds9
Breast Cancer: Challenges in the Treatment and Prodrug Strategies9
The Indispensable Roles of GMDS and GMDS-AS1 in the Advancement of Cancer: Fucosylation, Signal Pathway and Molecular Pathogenesis9
Levothyroxine and Non-alcoholic Fatty Liver Disease: A Mini Review9
Systematic Review of the Serotonergic System in the Pathophysiology of Severe Dengue: The Theory of Thrombocytopenia and Vascular Extravasation9
Cathepsin B-A Neuronal Death Mediator in Alzheimer’s Disease Leading to Neurodegeneration8
Lyophilization of Molecular Biology Reactions: A Review8
Naturally occurring and synthetic coumarin derivatives: Promising agents for managing neuroinflammation8
Meet the Associate Editorial Board Member8
An Updated and Focused Review on Heterocyclic Inhibitors for SARSCoV and SARS-CoV-2 3CLpro8
Bioactivities of Dietary Polyphenols and Their Effects on Intestinal Microbiota8
Dendrobine: A neuroprotective Sesquiterpenic Alkaloid for the Prevention and Treatment of Diseases: A Review8
Acknowledgements to Reviewers8
Meet the Associate Editorial Board Member8
LncRNA DSCAM-AS1: A Pivotal Therapeutic Target in Cancer8
Minoxidil as a Prodrug: Review of Chemical, Pharmacological, and Technological Aspects in Alopecia Therapeutics8
Recent Studies on the Pharmacological Activities and Structural Modifications of Compound-K8
Biological Activities of Morita-Baylis-Hillman Adducts (MBHA)8
Meet the Editorial Board Member8
Acknowledgement to Reviewers8
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