Mini-Reviews in Medicinal Chemistry

Article	Citations
Meet the Section Editor	93
Synthetic Approaches and Pharmacological Attributes of Benzosuberone Skeleton	81
The Progress of Small Molecule Targeting BCR-ABL in the Treatment of Chronic Myeloid Leukemia	58
Therapeutic Approaches for the Treatment of Interstitial Lung Disease: An Exploratory Review on Molecular Mechanisms	47
Withdrawal: Advances in Development of Drugs for Chronic Myelogenous Leukemia	46
Melatonin and Related Compounds as Antioxidants	46
Meet the Editorial Board Member	45
A Critical Observation on the Design and Development of Reported Peptide Inhibitors of DENV NS2B-NS3 Protease in the Last Two Decades	43
Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease	40
Cytotoxic Activity of Tropane Alkaloides of Species of Erythroxylum	40
Quinoxaline: A Chemical Moiety with Spectrum of Interesting Biological Activities	40
Meet Our Editorial Board Member	38
Meet Our Editorial Board Member	37
Acknowledgements to Reviewers	35
Meet Our Editorial Board Member	35
Recent Update on the Anti-infective Potential of β-carboline Analogs	33
Meet the Section Editor	33
Fenugreek Cultivation with Emphasis on Historical Aspects and its uses in Traditional Medicine and Modern Pharmaceutical Science	33
Protein and Small-Molecule Leucopoiesis and Thrombopoiesis Stimulators	31
Natural Products Databases for Drug Design	31
Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes	30
Meet the Editorial Board Member	29
Radical Releasing Anti-tuberculosis Agents and the Treatment of Mycobacterial Tuberculosis Infections - An Overview	29
Recent Developments in Shape-Controlled Synthesis of Cellulose Nanocrystals	28
Chemical Synthesis of Selenium-containing Peptides	27

Meet the Editorial Board Member	27
Cyclin-Dependent Kinase 4/6 Inhibitors Against Breast Cancer	26
Meet the Editorial Board Member	26
Roles of lncRNA-MALAT1 in the Progression and Prognosis of Gliomas	26
Role of Cathepsin B in Cancer Progression: A Potential Target for Coordination Compounds	26
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease	23
A Systematic Review of Machine Learning Based Gait Characteristics in Parkinson’s Disease	23
Thrombin - A Molecular Dynamics Perspective	23
Meet the Editorial Board Member	22
Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects	22
Review on Characteristics and Analytical Methods of Remogliflozin Etabonate: An Update	22
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review	22
Targeting Glioma Cells with Nutraceuticals: Therapeutic Effects Based on Molecular Mechanisms, New Evidence and Perspectives	21
An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus	20
Therapeutic Potental of Quinolin-2H-one Hybrids as Anticancer Agents	20
Review of 10,11-Dehydrocurvularin: Synthesis, Structural Diversity, Bioactivities and Mechanisms	19
DNA Interaction and Cytotoxic studies on Mono/Di-Oxo and Peroxo- Vanadium (V) complexes - A Review	18
A Therapeutic Journey of Potential Drugs Against COVID-19	18
Anti-mycobacterial Constituents from Medicinal Plants; A Review	18
Aptamers Against COVID-19: An Untested Opportunity	18
Mechanism of Natural Drugs on Nonalcoholic Fatty Liver Disease	17
Comprehensive Update on Synthetic Aspects of Bosentan Derivatives	17
Meet the Executive Guest Editor	17
Meet the Editorial Board Member	17
Second-line Therapy for Helicobacter Pylori Eradication: State of the Art	16
Meet the Editorial Board Member	16
Meet the Editorial Board Member	16
MiRNAs: Emerging Agents for Therapeutic Effects of Polyphenols on Ovarian Cancer	16
Meet the Editorial Board Member	16
Xanthone: Potential Acetylcholinesterase Inhibitor for Alzheimer's Disease Treatment	15
Multitarget Directed Ligand Approaches for Alzheimer’s Disease: A Comprehensive Review	15
Research Mechanism and Progress of the Natural Compound Curcumin in Treating Alzheimer´s Disease	15
A Review on Chemical Structures and Biological Activities of Dopamine Derivatives from Medicinal Insects	15
The Advances in Bioactivities, Mechanisms of Action and Structural Optimizations of Matrine and its Derivatives	15
Synthetic Approach to Potential Anticancer Benzimidazole Derivatives: A Review	15
Targeting Lysosomes: A Strategy Against Chemoresistance in Cancer	15
The Search for Antidotes Against Ricin	14
Purinergic Signaling and its Role in the Stem Cell Differentiation	14
The Therapeutic Potential and Molecular Mechanisms Underlying the Neuroprotective Effects of Sativex® - A Cannabis-derived Spray	14
The Most Recent Discoveries in Heterocyclic Nanoformulations for Targeted Anticancer Therapy	14
2-Substituted-mercapto-quinazolin-4(3H)-ones as DHFR Inhibitors	13
Diabetes Pharmacotherapy and its effects on the Skeletal Muscle Energy Metabolism	13
Multi-vesicular Liposome and its Applications: A Novel Chemically Modified Approach for Drug Delivery Application	13
A Review on Rotenoids: Purification, Characterization and its Biological Applications	13
Targeting STAT3 Enzyme for Cancer Treatment	13
In silico Approaches for Exploring the Pharmacological Activities of Benzimidazole Derivatives: A Comprehensive Review	13
Meet the Editorial Board Member	13
Development of Natural Bioactive Alkaloids: Anticancer Perspective	13
Nanomaterials for Deep Tumor Treatment	13
Insight into the Synthesis, Biological Activity, and Structure-activity Relationship of Benzothiazole and Benzothiazole-hydrazone Derivatives: A Comprehensive Review	12

Antidiabetic Properties of Dietary Chrysin: A Cellular Mechanism Review	12
Multi-Target Drug Design of Anti-Alzheimer’s Disease based on Tacrine	12
Structure, Biological Activities and Metabolism of Flavonoid Glucuronides	12
Recent Progress of Bioactivities, Mechanisms of Action, Total Synthesis, Structural Modifications and Structure-activity Relationships of Indole Derivatives: A Review	12
Bioactive Furanyl- or Thienyl-Substituted Nucleobases, Nucleosides and Their Analogues	12
Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions	12
The Situation of Small Molecules Targeting Key Proteins in combatting SARS-CoV-2: Synthesis, Metabolic Pathway, Mechanism of Action, and Potential Therapeutic Applications	12
A Comprehensive Review of Garcinia pedunculata Roxb. and its Therapeutic Potential	12
The Role of IL-6 Released During Exercise to Insulin Sensitivity and Muscle Hypertrophy	12
Recent Advancements on Benzimidazole: A Versatile Scaffold in Medicinal Chemistry	12
Exploration of Potent Multi-target-directed-ligands as Anti-alzheimer’s Disease Agents: A Moiety Based Review	11
The Effects of Apigenin in the Treatment of Diabetic Nephropathy: A Systematic Review of Non-clinical Studies	11
Chemistry, Analysis, and Biological Aspects of Daprodustat, A New Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor: A Comprehensive Review	11
Hypericin Ameliorates Maternal Separation-Induced Cognitive Deficits and Hippocampal Inflammation in Rats	11
Synthetic Methods of Quinoxaline Derivatives and their Potential Anti-inflammatory Properties	11
Virtual Screening of Natural Products Database	11
The Role of LncRNA TUG1 in Obesity-related Diseases	11
Therapeutic Potential of Resveratrol in the Treatment of Glioma: Insights into its Regulatory Mechanisms	11
Toward Early Diagnosis of Colorectal Cancer: Focus on Optical Nano Biosensors	11
Recent Progress in Anticancer Agents Incorporating Pyrazole Scaffold	11
A Review on a Medicinal and Edible Plant: Aralia elata (Miq.) Seem.	11
Immunotherapy in Combination with Chemotherapy for Triple-negative Breast Cancer	11
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics	11
Recent Progress and Perspectives in Sodium-Glucose Co-transporter 1/2 Inhibitors	11
Anti-aging Natural Compounds and their Role in the Regulation of Metabolic Pathways Leading to Longevity	11
Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review	11
Nuclear Medicine Application of Pentixafor/Pentixather Targeting CXCR4 for Imaging and Therapy in Related Disease	11
Antimicrobial Properties of Mandelic Acid, Gallic Acid and their Derivatives	10
From Traditional Use to Modern Evidence: The Medicinal Chemistry of Antimalarials from Genus Artemisia	10
Meet Our Editorial Board Member	10
S-adenosyl-L-homocysteine Hydrolase: Its Inhibitory Activity Against Plasmodium falciparum and Development of Malaria Drugs	10
Chitosan: Applications in Drug Delivery System	10
Quinoline: An Attractive Scaffold in Drug Design	10
Meet the Frontier Section Editor	10
Preface	10
Sustainable Synthesis of Medicinally Important Heterocycles	10
Current Perspective of Synthesis of Medicinally Relevant Benzothiazole based Molecules: Potential for Antimicrobial and Anti-Inflammatory Activities	10
Recent Applications of Azo Dyes: A Paradigm Shift from Medicinal Chemistry to Biomedical Sciences	10
The Application of the Pyrazole Structure in the Structural Modification of Natural Products	10
Recent Progress in Andrographolide Derivatization: Structural Modification and Biological Activity	10
Novel Niacin Receptor Agonists: A Promising Strategy for the Treatment of Dyslipidemia	9
Advances on the Anti-Inflammatory Activity of Oleanolic Acid and Derivatives	9
Meet the Editorial Board Member	9
Plant Based Natural Products as Quorum Sensing Inhibitors in E. Coli: A Critical Review	9
Targeting of ErbB1, ErbB2, and their Dual Targeting Using Small Molecules and Natural Peptides: Blocking EGFR Cell Signaling Pathways in Cancer: A Mini-Review	9
Biological Activities, Pharmacokinetics and Toxicity of Nootkatone: A Review	9
Nano-biotechnology and its Innovative Perspective in Diabetes Management	9
Meet Our Editorial Board Member	9
New Scope of Targeted Therapies in Lung Carcinoma	9
Meet the Editorial Board Member	9
The Role of EGCG in Breast Cancer Prevention and Therapy.	9
A Mini Review on Emerging Targets and Approaches for the Synthesis of Anti-viral Compounds: In Perspective to COVID-19	9
Meet the Editorial Board Member	9
The Zinc-dependent HDACs: Non-histone Substrates and Catalytic Deacylation Beyond Deacetylation	9
The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)	8
A Review on Structure-Activity Relationships of Glycyrrhetinic Acid Derivatives with Diverse Bioactivities	8
The Recent Developments of ADCs with the Tubulysins as the Payloads	8
A Review and Meta-analysis on Trastuzumab Resistance in Patients with HER2+ Breast Cancer	8
Comprehensive Review on Recent Strategies for Management of Prostate Cancer: Therapeutic Targets and SAR	8
The Application of MD Simulation to Lead Identification, Vaccine Design, and Structural Studies in Combat against Leishmaniasis - A Review	8
Natural Bridged Bicyclic Peptide Macrobiomolecules from Celosia argentea and Amanita phalloides	8
Meet the Editorial Board Member	8
A Review on Therapeutic Strategies against Parkinson’s Disease: Current Trends and Future Perspectives	8
Targeting Ion Channels for the Treatment of Glioma	8
Recent Insights of Metformin on Hepatocellular Carcinoma (HCC)	8
Recent Development in Substituted Benzothiazole as an Anticonvulsant Agent	8
The most Recent Compilation of Reactions of Enaminone Derivatives with various Amine Derivatives to Generate Biologically Active Compounds	8
The Rising Risk of Chronic Kidney Disease (CKD) and How it is Dealt with: A Review of Current and Potential Phosphate Binders (PB)	8
Advances in Exercise Therapy in Hemodialysis: A Systematic Review	8
Methyl-linked Pyrazoles: Synthetic and Medicinal Perspective	8
Recent Advances in PI3 Kinase Inhibitors: Anticancer Activities and Structure-Activity Relationships	8
Update on Acrylic Resins Used in Dentistry	8
Molecular Dynamics Simulations in Drug Discovery	8
Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry	8
KRAS Pathway-based Therapeutic Approaches in Pancreatic Cancer	7
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications	7
SMAC Mimetics for the Treatment of Lung Carcinoma: Present Development and Future Prospects	7
Current Biomedical and Diagnostic Applications of Gold Micro and Nanoparticles	7
New Insights into the Modifications and Bioactivities of Indole-3-Carboxaldehyde and its Derivatives as a Potential Scaffold for Drug Design: A Mini-Review	7
Recent Development of DNA Gyrase Inhibitors: An Update	7

Chemistry, Pharmacokinetics, Pharmacodynamics and Analytical Methods of Bilastine, a Histamine H1 Receptor Antagonist: An Update	7
SARS-CoV-2 Infections, Impaired Tissue, and Metabolic Health: Pathophysiology and Potential Therapeutics	7
Poly(ADP-Ribose) Polymerase-1 Inhibitors Drug Discovery, Design, and Development as Anticancer Agents from Past to Present: A Mini-Review	7
Mediterranean Diet Polyphenols: Anthocyanins and Their Implications for Health	7
Chromenes - A Novel Class of Heterocyclic Compounds: Recent Advancements and Future Directions	7
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells	7
Topical Application onto the Eyelid Skin: Is it a Feasible Delivery Route of Ophthalmic Drugs?	7
A Review of the Synthesis of Nitric Oxide Donor and Donor Derivatives with Pharmacological Activities	7
Clinical Utility of Soluble CD163 and its Diagnostic and Prognostic Value in a Variety of Neurological Disorders	7
Bioactive Sulfonamides Derived from Amino Acids: Their Synthesis and Pharmacological Activities	7
Chemotherapeutic Strategies for Combating Staphylococcus aureus Infections	7
Narrative Review of the Pharmacodynamics, Pharmacokinetics, and Toxicities of Illicit Synthetic Cannabinoid Receptor Agonists	7
Meet the Editorial Board Member	7
Revolutionizing Playing with Skeleton Atoms: Molecular Editing Surgery in Medicinal Chemistry	7
Tuberculosis, BCG Vaccination, and COVID-19: Are They Connected?	7
Janus Kinase Inhibitors: A Review of Their Application in the Vitiligo	6
The Potential Application of Novel Drug Delivery Systems for Phytopharmaceuticals and Natural Extracts – Current Status and Future Perspectives	6
Meet the Editor-in-Chief	6
Quorum Sensing Regulation as a Target for Antimicrobial Therapy	6
An Approach to Pharmacological Targets of Pyrrole Family From Medicinal Chemistry Viewpoint	6
Neuroendocrinological and Clinical Aspects of Leptin	6
Effectiveness of Azithromycin as Add-on Therapy in COVID-19 Management	6
Small-Molecule Drugs in Immunotherapy	6
Resistance to Intervention: Paclitaxel in Breast Cancer	6
A Panoramic Review of Benzimidazole Derivatives and their Potential Biological Activity	6
Tanshinone IIA Against Cerebral Ischemic Stroke and Ischemia- Reperfusion Injury: A Review of the Current Documents	6
Pharmacologic Activities of 5, 6-Diaryl/heteroaryl-3-substituted-1, 2, 4- triazines as a Privileged Scaffold in Drug Development	6
The Roles of Cytoplasmic Polyadenylation Element Binding Protein 1 in Tumorigenesis	6
Research Progress of Essential Oil as a New Complementary Therapy in the Treatment of Depression	6
A Rapid Qualitative Review of Sarcoidosis: Clinical Manifestations, Immunopathogenesis, Diagnosis and Treatment	6
Molecular Targets for Chalcones in Antileishmanial Drug Discovery	6
Emerging Need of Today: Significant Utilization of Various Databases and Softwares in Drug Design and Development	6
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and Chemical Synthesis Approach	6
An Insight into the Polymeric Nanoparticles Applications in Diabetes Diagnosis and Treatment	6
Quantum Dots as Theranostic Agents: Recent Advancements, Surface Modifications, and Future Applications	6
1,8-Naphthyridine Derivatives: A Privileged Scaffold for Versatile Biological Activities	6
Research Progress on the Natural Product Aloperine and Its Derivatives	6
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases	6
Insight in Quinazoline-based HDAC Inhibitors as Anti-cancer Agents	6
CRISPR-Cas9 Genome Engineering: Trends in Medicine and Health	6
Antiviral Flavonoids: A Natural Scaffold with Prospects as Phytomedicines against SARS-CoV2	6
Recent Advances in Natural Products with Antiviral Activities	6
Aloe-emodin: Progress in Pharmacological Activity, Safety, and Pharmaceutical Formulation Applications	6
Anti-Tubercular Activity of Pyrazinamide Conjugates: Synthesis and Structure-Activity Relationship Studies	6
Progress in Research on CNPY2 in Diseases	6
A Recent Appraisal of Artificial Intelligence and In Silico ADMET Prediction in the Early Stages of Drug Discovery	6
Anthriscus sylvestris: An overview on Bioactive Compounds and Anticancer Mechanisms from a Traditional Medicinal Plant to Modern Investigation	6
Oncopreventive and Oncotherapeutic Potential of Licorice Chalcone Compounds: Molecular Insights	6