Mini-Reviews in Medicinal Chemistry

Article	Citations
Comprehensive Update on Synthetic Aspects of Bosentan Derivatives	67
Antisense Molecules: Design, Chemistry, and Therapeutic Innovations	57
Synthesis of Phenothiazine Derivatives and their Diverse Biological Activities: A Review	56
Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes	56
A Systematic Review On ERK/MAPK Signaling Circuit As The Critical Regulator In Chronic Wound Healing: Phytochemicals As Possible Modulators?	53
Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects	49
Targeting Lysosomes: A Strategy Against Chemoresistance in Cancer	47
Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease	41
Relationship Between miRNA and Neurodegenerative Diseases Such as Alzheimer's disease, Parkinson's, Huntington's disease, Amyotrophic Lateral Sclerosis	41
Current Perspective of Synthesis of Medicinally Relevant Benzothiazole based Molecules: Potential for Antimicrobial and Anti-Inflammatory Activities	41
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease	39
A Review on Chemical Structures and Biological Activities of Dopamine Derivatives from Medicinal Insects	39
The Role of IL-6 Released During Exercise to Insulin Sensitivity and Muscle Hypertrophy	37
Meet the Editorial Board Member	34
An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus	34
Meet the Editorial Board Member	33
Meet the Editorial Board Member	33
Meet the Editorial Board Member	32
Regulatory T Cells: Subtle and Promising Achilles' Heel of Psoriasis - Atherosclerosis Comorbidity	29
Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome	29
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells	28
Advances in Exercise Therapy in Hemodialysis: A Systematic Review	28
Revolutionizing Playing with Skeleton Atoms: Molecular Editing Surgery in Medicinal Chemistry	28
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and Chemical Synthesis Approach	28
KRAS Pathway-based Therapeutic Approaches in Pancreatic Cancer	27

The most Recent Compilation of Reactions of Enaminone Derivatives with various Amine Derivatives to Generate Biologically Active Compounds	27
Bioactive Sulfonamides Derived from Amino Acids: Their Synthesis and Pharmacological Activities	27
Associate Editorial Board Members	26
Research Progress in Alpha-fetoprotein-induced Immunosuppression of Liver Cancer	25
Overview of Piperine: Bioactivities, Total Synthesis, Structural Modification, and Structure-Activity Relationships	25
Natural Products with BACE1 and GSK3β Inhibitory Activity	24
Recent Advancements in Strategies for Abnormal Protein Clearance in Alzheimer's Disease	24
Meet the Section Editor	23
Molecular Insights on the Therapeutic Effect of Selected Flavonoids on Diabetic Neuropathy	23
A Review of the Role of Poly (ADP-Ribose) Polymerase-1 (PARP1) and Its Inhibitors for Cancer Therapy	23
Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin’s Lymphoma	22
The Role of MiR-29 in the Mechanism of Fibrosis	22
The Pivotal Function of SLC16A1 and SLC16A1-AS1 in Cancer Progress: Molecular Pathogenesis and Prognosis	22
A Review on Acridines as Antiproliferative Agents	22
Medicinal Plants in Cancer Treatment: Contribution of Nuclear Factor- Kappa B (NF-kB) Inhibitors	22
Inhibitors of Epigenetic Modulators as Therapeutic Alternatives for Cardiovascular Diseases	21
Role of TBK1 Inhibition in Targeted Therapy of Cancer	21
Meet the Frontiers Section Editor	20
Breaking Barriers in Breast Cancer: Multi-Targeted Therapeutic Insights	20
Cinnamic Acid Derivatives: Recent Discoveries and Development Strategies for Alzheimer’s Disease	20
Meet the Editorial Board Member	20
Psilocybin: Chemical Foundations and Emerging Therapeutic Potential	20
Marine-Derived Fucoidan in Cancer Therapy: Mechanistic Insights, Clinical Prospects, and Future Directions	19
Roles of Accelerated Molecular Dynamics Simulations in Predictions of Binding Kinetic Parameters	19
Green-synthesized titanium dioxide nanoparticles: systematic review of antimicrobial efficacy and biocompatibility	19
AGAP2-AS1: An Indispensable lncRNA in Tumors	19
Physicochemical Properties, Drug Delivery, and Tissue Engineering Applications of Neem Gum and Its Derivatives: A Comprehensive Review	18
Substituted Benzofurans as Potent Anticancer Agents: Advances, Molecular Docking, and SAR Studies	18
Critical Relationship Between Iron Deficiency Anaemia (IDA) and Glycated Haemoglobin (HbA1c): An Updated Review	18
Research Hotspots and Trends of Artificial Intelligence in Drug Discovery: A Review and Bibliometric Analysis	17
Herbal Extract-loaded Biomaterials for Bone Regeneration: Mechanisms of Action, Delivery Platform Optimization, and Translational Considerations	17
Recent Literature on the Synthesis of Thiazole Derivatives and their Biological Activities	17
Natural Products as Autophagy-related Protein Kinase Inhibitors: A Future Promising Anticancer from Nature	17
Medicinal Chemistry Perspectives on Molecular Targets and Targeted Therapeutic Strategies in Breast Cancer	17
Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings	17
Quinoline Derivatives as Promising Scaffolds for Antitubercular Activity: A Comprehensive Review	17
Innovative Approaches to Alzheimer's Treatment: Utilizing Tacrine Hybrids to Inhibit Amyloid Beta Aggregation as a Strategic Focus	16
Nimbolide: A Potential Phytochemical Agent in Multimodal Pancreatic Cancer Therapies	16
The Effects of Increased Glucose Level and Glycolysis on SARS CoV-2 Infection	16
N-Methyl-D-Aspartate (NMDA)-Type Glutamate Receptors and Demyelinating Disorders: A Neuroimmune Perspective	16
Flavonoid-metal ion Complexes as Potent Anticancer Metallodrugs: A Comprehensive Review	16
Homometallic Polynuclear Rhodium Complexes in Anticancer Drug Development	16
Development of Triazole based Anticonvulsants through Various Catalytic Approaches	16
Meet the Editorial Board Member	16
The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease	16
Natural Products, Synthesis, and Biological Activities of Quinolines (2020-2024)	16
Current Status of and Perspectives on Radiolabelled Ubiquicidin 29-41 Derivatives for Bacterial Infection Imaging	16
Meet the Editorial Board Member	15
Meet the Editor-in-Chief	15
Chemical Strategies Toward Prodrugs and Fluorescent Probes for Gasotransmitters	15

The Art and Science of Antidiabetic Medications and Obesity Management	15
MicroRNAs and Efferocytosis: Implications for Diagnosis and Therapy	15
Meet the Editorial Board Member	15
Meet the Editorial Board Member	15
Drug Repurposing: A Conduit to Unravelling Metabolic Reprogramming for Cancer Treatment	15
Development of Mycobacterium tuberculosis Enoyl Acyl Reductase (InhA) Inhibitors: A Mini-Review	15
A Comprehensive Review on Chemistry and Biology of Tafamidis in Transthyretin Amyloidosis	15
An Overview of Pyridazinone Analogs: Chemical and Pharmacological Potential	14
Therapeutic Potentials of Aconite-like Alkaloids: Bioinformatics and Experimental Approaches	14
The Complex Roles of DNA Repair Pathways, Inhibitors, Hyperthermia, and Contact Inhibition in Cell Cycle Halts	14
Comprehensive Insight into Green Synthesis Approaches, Structural Activity Relationship, and Therapeutic Potential of Pyrazolic Chalcone Derivative	14
Strategies in Taxol Development: A Review	14
PARP1 as a Central Node in DNA Repair and Epigenetic Regulation: Implications for Biomarker Discovery and Targeted Therapy in NSCLC	14
Exploring the Therapeutic Potential of Coumarin Scaffolds in Alzheimer's Disease: A Comprehensive Review	14
Inhibitors Targeting Hepatitis C Virus (HCV) Entry	14
Potential of Small Molecule TAAR-1 Agonists for the Therapy of Neurodegenerative Psychosis: A Medicinal Chemistry Perspective	14
Meet the Editorial Board Member	13
Second-line Therapy for Helicobacter Pylori Eradication: State of the Art	13
A Therapeutic Journey of Potential Drugs Against COVID-19	13
Meet the Editorial Board Member	13
Energy Metabolism Behavior and Response to Microenvironmental Factors of the Experimental Cancer Cell Models Differ from that of Actual Human Tumors	13
The Application of the Pyrazole Structure in the Structural Modification of Natural Products	13
Meet the Editorial Board Member	13
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics	13
Nuclei-targeted Therapeutic Delivery: A Novel Concept for the Treatment of Cancer	13
Chemistry, Analysis, and Biological Aspects of Daprodustat, A New Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor: A Comprehensive Review	13
Melatonin and Related Compounds as Antioxidants	12
Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review	12
Therapeutic Approaches for the Treatment of Interstitial Lung Disease: An Exploratory Review on Molecular Mechanisms	12
Evaluation of Melatonin and its Nanostructures Effects on Skin Disorders Focused on Wound Healing	12
Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions	12
The Therapeutic Potential and Molecular Mechanisms Underlying the Neuroprotective Effects of Sativex® - A Cannabis-derived Spray	12
Sulfonamides in Drug Discovery: A Review of Synthetic Approaches and Biological Activities	12
Triazolopyridazines as Privileged Heterocyclic Scaffolds: Advances in Synthesis, Structure- Activity Relationship and Therapeutic Applications	12
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review	12
The Search for Antidotes Against Ricin	12
In vivo Pharmacokinetic and ADMET Profiles of Synthetic Antimicrobial Peptides (AMPs)	12
Recent Developments in Common Dietary Phytoconstituents: Insights into Structure-activity Relationship and Anti-breast Cancer Activity	11
Structural and Electronic Determinants Underlying the Biofunctional Profile of Isothiocyanates: A Structure-activity Insight	11
Recent Advancements and SAR Studies of Synthetic Coumarins as MAO-B Inhibitors: An Updated Review	11
Anthriscus sylvestris: An overview on Bioactive Compounds and Anticancer Mechanisms from a Traditional Medicinal Plant to Modern Investigation	11
New Insights into the Modifications and Bioactivities of Indole-3- Carboxaldehyde and its Derivatives as a Potential Scaffold for Drug Design: A Mini-Review	11
Narrative Review of the Pharmacodynamics, Pharmacokinetics, and Toxicities of Illicit Synthetic Cannabinoid Receptor Agonists	11
Antimicrobial Efficacy and Mechanistic Insights of 0D, 1D, 2D, and 3D Nanoparticles: A Review	11
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications	11
The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)	11
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases	11
Recent Insights of Metformin on Hepatocellular Carcinoma (HCC)	10
Cardiovascular Effects of Ruthenium Complexes: A Potential Therapeutic Tool in Hypertension and Myocardial Injury	10
Recent Advances in Benzoxazole Derivatives: Pharmacological Potential and Therapeutic Applications	10
Nicotinamide Adenine Dinucleotide in the Development and Treatment of Cardiac Remodeling and Aging	10
Research Progress in Mutagenesis Techniques for Aspergillus fumigatus and the Biological Activities of Fumagillin	10
Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry	10
Synthesis and Biological Properties of Isatin-indole Hybrids: A Review	10
Recent Development of CXCR4-Targeted Nuclear Medicine Research in Adrenocortical Tumors	10
Aloe-emodin: Progress in Pharmacological Activity, Safety, and Pharmaceutical Formulation Applications	10
Meet the Editorial Board Member	10
Targeting Bcl-2 with Indole Scaffolds: Emerging Drug Design Strategies for Cancer Treatment	10
A Short Review on Glucogallin and its Pharmacological Activities	10
Aptamer-carbon Nanotube Hybrids: Emerging Frontiers in Biomedical Diagnostics and Therapeutics	9
Meet the Editorial Board Member	9
Recent Studies on the Pharmacological Activities and Structural Modifications of Compound-K	9
The Indispensable Roles of GMDS and GMDS-AS1 in the Advancement of Cancer: Fucosylation, Signal Pathway and Molecular Pathogenesis	9
Agent in Urgent Need of Clinical Practice: Corilagin	9
Meet the Editorial Board Member	9
Meet the Co-Editor	9
Systematic Review of the Serotonergic System in the Pathophysiology of Severe Dengue: The Theory of Thrombocytopenia and Vascular Extravasation	9
Protective Effect of Plumeria Pudica Latex Proteins on Intestinal Mucositis Induced by 5-Fluorouracil	9
Meet the Editor in Chief	9
Pharmacological Modulation of Apoptosis and Autophagy in Pancreatic Cancer Treatment	9
Natural Product-based Therapies for Inflammatory Bowel Disease: Targeting Key Signaling Pathways	9
The Use of Nanocarriers to Enhance the Anti-neuroinflammatory Potential of Dietary Flavonoids in Animal Models of Neurodegenerative Diseases: A Systematic Review	8
Cathepsin B-A Neuronal Death Mediator in Alzheimer’s Disease Leading to Neurodegeneration	8
Dendrobine: A neuroprotective Sesquiterpenic Alkaloid for the Prevention and Treatment of Diseases: A Review	8
Naturally occurring and synthetic coumarin derivatives: Promising agents for managing neuroinflammation	8
Biological Activities of Morita-Baylis-Hillman Adducts (MBHA)	8
Acknowledgements to Reviewers	8
Minoxidil as a Prodrug: Review of Chemical, Pharmacological, and Technological Aspects in Alopecia Therapeutics	8
MCM3AP-AS1: A LncRNA Participating in the Tumorigenesis of Cancer Through Multiple Pathways	8
Interesting Potential Derivatives Based on the Coumarin Scaffold for the Treatment of Alzheimer's Disease	8

Natural and Synthetic Phosphodiesterase Inhibitors in 2023: an Update on the Impact on Neurological and Psychiatric Conditions	8
Fungal Endophytes: A Storehouse of Bioactive Compounds	8
Recent Advances in Small Molecular PET Tracers for Pancreatic Cancer Diagnosis: Preclinical Stage	8
Bioactivities of Dietary Polyphenols and Their Effects on Intestinal Microbiota	8
Breast Cancer: Challenges in the Treatment and Prodrug Strategies	8
Levothyroxine and Non-alcoholic Fatty Liver Disease: A Mini Review	8
LncRNA DSCAM-AS1: A Pivotal Therapeutic Target in Cancer	8
Meet the Associate Editorial Board Member	8
Lyophilization of Molecular Biology Reactions: A Review	8