Mini-Reviews in Medicinal Chemistry

Papers
(The TQCC of Mini-Reviews in Medicinal Chemistry is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
A Review on Chemical Structures and Biological Activities of Dopamine Derivatives from Medicinal Insects125
Targeting Lysosomes: A Strategy Against Chemoresistance in Cancer84
Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease78
Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes54
Comprehensive Update on Synthetic Aspects of Bosentan Derivatives54
An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus51
The Role of IL-6 Released During Exercise to Insulin Sensitivity and Muscle Hypertrophy51
Synthesis of Phenothiazine Derivatives and their Diverse Biological Activities: A Review49
Current Perspective of Synthesis of Medicinally Relevant Benzothiazole based Molecules: Potential for Antimicrobial and Anti-Inflammatory Activities47
Quinoxaline: A Chemical Moiety with Spectrum of Interesting Biological Activities47
Natural Products Databases for Drug Design45
Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects45
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease43
Synthetic Approach to Potential Anticancer Benzimidazole Derivatives: A Review41
Aptamers Against COVID-19: An Untested Opportunity41
Multitarget Directed Ligand Approaches for Alzheimer’s Disease: A Comprehensive Review41
Meet the Editorial Board Member40
Meet the Editorial Board Member39
Chemotherapeutic Strategies for Combating Staphylococcus aureus Infections38
Meet the Editorial Board Member38
Advances in Exercise Therapy in Hemodialysis: A Systematic Review38
Meet the Editorial Board Member38
KRAS Pathway-based Therapeutic Approaches in Pancreatic Cancer35
Revolutionizing Playing with Skeleton Atoms: Molecular Editing Surgery in Medicinal Chemistry31
Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome30
The most Recent Compilation of Reactions of Enaminone Derivatives with various Amine Derivatives to Generate Biologically Active Compounds29
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and Chemical Synthesis Approach29
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells29
Regulatory T Cells: Subtle and Promising Achilles' Heel of Psoriasis - Atherosclerosis Comorbidity28
Bioactive Sulfonamides Derived from Amino Acids: Their Synthesis and Pharmacological Activities28
Anticancer Potential of Coumarin and its Derivatives28
Recent Advancements in Strategies for Abnormal Protein Clearance in Alzheimer's Disease27
Meet the Editorial Board Member27
Molecular Insights on the Therapeutic Effect of Selected Flavonoids on Diabetic Neuropathy27
Associate Editorial Board Members27
Pharmacological Efficacy and Safety of Glycyrrhiza glabra in the Treatment of Respiratory Tract Infections27
Natural Products with BACE1 and GSK3β Inhibitory Activity26
Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives26
Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin’s Lymphoma26
The Pivotal Function of SLC16A1 and SLC16A1-AS1 in Cancer Progress: Molecular Pathogenesis and Prognosis24
A Review on Acridines as Antiproliferative Agents24
Cinnamic Acid Derivatives: Recent Discoveries and Development Strategies for Alzheimer’s Disease23
Meet the Section Editor23
Research Progress in Alpha-fetoprotein-induced Immunosuppression of Liver Cancer22
Medicinal Plants in Cancer Treatment: Contribution of Nuclear Factor- Kappa B (NF-kB) Inhibitors21
Antioxidant, Anti-inflammatory, Antibacterial, and Analgesic Activities and Mechanisms of Quinolines, Indoles and Related Derivatives21
Inhibitors of Epigenetic Modulators as Therapeutic Alternatives for Cardiovascular Diseases21
Overview of Piperine: Bioactivities, Total Synthesis, Structural Modification, and Structure-Activity Relationships21
Meet the Frontiers Section Editor20
Meet the Editorial Board Member20
The Role of MiR-29 in the Mechanism of Fibrosis20
Meet the Editorial Board Member20
Role of TBK1 Inhibition in Targeted Therapy of Cancer20
Recent Literature on the Synthesis of Thiazole Derivatives and their Biological Activities19
Quinoline Derivatives as Promising Scaffolds for Antitubercular Activity: A Comprehensive Review19
AGAP2-AS1: An Indispensable lncRNA in Tumors19
Drug Solubilization by Surfactants: Experimental Methods and Theoretical Perspectives19
Roles of Accelerated Molecular Dynamics Simulations in Predictions of Binding Kinetic Parameters19
Carbohydrazide Analogues: A Review of Synthesis and Biological Activities19
Nimbolide: A Potential Phytochemical Agent in Multimodal Pancreatic Cancer Therapies18
Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings18
Meet the Editorial Board Member18
Recent Advances in the Development of Type 2 Sodium-Glucose Cotransporter Inhibitors for the Treatment of Type 2 Diabetes Mellitus18
Breaking Barriers in Breast Cancer: Multi-Targeted Therapeutic Insights18
Development of Mycobacterium tuberculosis Enoyl Acyl Reductase (InhA) Inhibitors: A Mini-Review17
The Art and Science of Antidiabetic Medications and Obesity Management17
Curcumin: An Insight into Molecular Pathways Involved in Anticancer Activity17
Flavonoid-metal ion Complexes as Potent Anticancer Metallodrugs: A Comprehensive Review17
Current Status of and Perspectives on Radiolabelled Ubiquicidin 29-41 Derivatives for Bacterial Infection Imaging17
SET Protein in Cancer: A Potential Therapeutic Target17
Homometallic Polynuclear Rhodium Complexes in Anticancer Drug Development16
Meet the Editorial Board Member16
N-Methyl-D-Aspartate (NMDA)-Type Glutamate Receptors and Demyelinating Disorders: A Neuroimmune Perspective16
The Effects of Increased Glucose Level and Glycolysis on SARS CoV-2 Infection16
Natural Products, Synthesis, and Biological Activities of Quinolines (2020-2024)16
Drug Repurposing: A Conduit to Unravelling Metabolic Reprogramming for Cancer Treatment16
The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease16
Quinoxaline 1,4-di-N-Oxide Derivatives: Are They Unselective or Selective Inhibitors?16
MicroRNAs and Efferocytosis: Implications for Diagnosis and Therapy16
Meet the Editorial Board Member15
Meet the Editorial Board Member15
Meet the Editorial Board Member15
Meet the Editor-in-Chief15
Inhibitors Targeting Hepatitis C Virus (HCV) Entry14
Effects of Urtica dioica on Metabolic Profiles in Type 2 Diabetes: A Systematic Review and Meta-analysis of Clinical Trials14
The Complex Roles of DNA Repair Pathways, Inhibitors, Hyperthermia, and Contact Inhibition in Cell Cycle Halts14
Therapeutic Potentials of Aconite-like Alkaloids: Bioinformatics and Experimental Approaches14
Chemical Strategies Toward Prodrugs and Fluorescent Probes for Gasotransmitters14
A Comprehensive Review on Chemistry and Biology of Tafamidis in Transthyretin Amyloidosis14
Origins, Structures, and Bioactivities of Secondary Metabolites from Marine-derived Penicillium Fungi14
Strategies in Taxol Development: A Review14
Comprehensive Insight into Green Synthesis Approaches, Structural Activity Relationship, and Therapeutic Potential of Pyrazolic Chalcone Derivative14
Recent Updates on Sinularia Soft Coral14
Glycyrrhizin as a Potential Treatment for the Novel Coronavirus (COVID-19)14
An Overview of Pyridazinone Analogs: Chemical and Pharmacological Potential14
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review13
The Search for Antidotes Against Ricin13
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics13
Meet the Editorial Board Member13
Chemistry, Analysis, and Biological Aspects of Daprodustat, A New Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor: A Comprehensive Review13
A Critical Observation on the Design and Development of Reported Peptide Inhibitors of DENV NS2B-NS3 Protease in the Last Two Decades13
Meet the Editorial Board Member13
Second-line Therapy for Helicobacter Pylori Eradication: State of the Art13
Meet the Editorial Board Member13
Meet the Editorial Board Member13
The Situation of Small Molecules Targeting Key Proteins in combatting SARS-CoV-2: Synthesis, Metabolic Pathway, Mechanism of Action, and Potential Therapeutic Applications12
Nuclei-targeted Therapeutic Delivery: A Novel Concept for the Treatment of Cancer12
A Therapeutic Journey of Potential Drugs Against COVID-1912
A Review on a Medicinal and Edible Plant: Aralia elata (Miq.) Seem.12
Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions12
Energy Metabolism Behavior and Response to Microenvironmental Factors of the Experimental Cancer Cell Models Differ from that of Actual Human Tumors12
Therapeutic Approaches for the Treatment of Interstitial Lung Disease: An Exploratory Review on Molecular Mechanisms12
Melatonin and Related Compounds as Antioxidants12
Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review12
The Therapeutic Potential and Molecular Mechanisms Underlying the Neuroprotective Effects of Sativex® - A Cannabis-derived Spray12
Radical Releasing Anti-tuberculosis Agents and the Treatment of Mycobacterial Tuberculosis Infections - An Overview12
In vivo Pharmacokinetic and ADMET Profiles of Synthetic Antimicrobial Peptides (AMPs)12
The Application of the Pyrazole Structure in the Structural Modification of Natural Products12
Antioxidant Activity of 1,2,4-Triazole and its Derivatives: A Mini-Review11
Xanthone: Potential Acetylcholinesterase Inhibitor for Alzheimer's Disease Treatment11
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications11
New Insights into the Modifications and Bioactivities of Indole-3- Carboxaldehyde and its Derivatives as a Potential Scaffold for Drug Design: A Mini-Review11
Acknowledgements to Reviewers11
Agent in Urgent Need of Clinical Practice: Corilagin11
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases11
Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry11
Anthriscus sylvestris: An overview on Bioactive Compounds and Anticancer Mechanisms from a Traditional Medicinal Plant to Modern Investigation11
Narrative Review of the Pharmacodynamics, Pharmacokinetics, and Toxicities of Illicit Synthetic Cannabinoid Receptor Agonists11
Novel Niacin Receptor Agonists: A Promising Strategy for the Treatment of Dyslipidemia11
Recent Insights of Metformin on Hepatocellular Carcinoma (HCC)11
Protective Effect of Plumeria Pudica Latex Proteins on Intestinal Mucositis Induced by 5-Fluorouracil11
Targeting Bcl-2 with Indole Scaffolds: Emerging Drug Design Strategies for Cancer Treatment11
Aloe-emodin: Progress in Pharmacological Activity, Safety, and Pharmaceutical Formulation Applications11
Recent Advancements and SAR Studies of Synthetic Coumarins as MAO-B Inhibitors: An Updated Review11
The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)11
Evaluation of Melatonin and its Nanostructures Effects on Skin Disorders Focused on Wound Healing11
Meet the Editorial Board Member11
Nicotinamide Adenine Dinucleotide in the Development and Treatment of Cardiac Remodeling and Aging11
Chromone, A Privileged Scaffold in Drug Discovery: Developments in the Synthesis and Bioactivity11
Cardiovascular Effects of Ruthenium Complexes: A Potential Therapeutic Tool in Hypertension and Myocardial Injury10
A Short Review on Glucogallin and its Pharmacological Activities10
Recent Development of CXCR4-Targeted Nuclear Medicine Research in Adrenocortical Tumors10
Meet the Editorial Board Member10
Meet the Editorial Board Member10
Natural and Synthetic Phosphodiesterase Inhibitors in 2023: an Update on the Impact on Neurological and Psychiatric Conditions10
Modulation of Long Non-coding RNAs by Different Classes of Secondary Metabolites from Plants: A Mini-review on Antitumor Effects10
Anticancer Potential of Naringenin, Biosynthesis, Molecular Target, and Structural Perspectives10
Advances in Biocatalytic Synthesis, Pharmacological Activities, Pharmaceutical Preparation and Metabolism of Ginsenoside Rh210
Meet the Co-Editor10
Recent Progress Towards Vaccines and Antibody-based Therapies Against Alzheimer's Disease10
Recent Studies on the Pharmacological Activities and Structural Modifications of Compound-K10
Synthesis and Biological Properties of Isatin-indole Hybrids: A Review10
Peroxisome Proliferator-activated Receptor-γ As A Novel and Promising Target For Treating Cancer Via Regulation of Inflammation: A Brief Review10
Research Progress in Mutagenesis Techniques for Aspergillus fumigatus and the Biological Activities of Fumagillin10
Some Scaffolds as Anti-leishmanial Agents: A Review10
Meet the Editor in Chief10
The Indispensable Roles of GMDS and GMDS-AS1 in the Advancement of Cancer: Fucosylation, Signal Pathway and Molecular Pathogenesis10
Meet the Executive Guest Editor10
Systematic Review of the Serotonergic System in the Pathophysiology of Severe Dengue: The Theory of Thrombocytopenia and Vascular Extravasation9
Cathepsin B-A Neuronal Death Mediator in Alzheimer’s Disease Leading to Neurodegeneration9
Biological Activities of Morita-Baylis-Hillman Adducts (MBHA)9
Acknowledgements to Reviewers9
Fungal Endophytes: A Storehouse of Bioactive Compounds9
Elucidating the Drug Repurposing Spectra of COVID-19 with its Analogues SARS and MERS9
Dendrobine: A neuroprotective Sesquiterpenic Alkaloid for the Prevention and Treatment of Diseases: A Review9
Levothyroxine and Non-alcoholic Fatty Liver Disease: A Mini Review9
An Updated Review of Various Medicinal Applications of p-Co umaric Acid: From Antioxidative and Anti-Inflammatory Properties to Effects on Cell Cycle and Proliferation9
LncRNA DSCAM-AS1: A Pivotal Therapeutic Target in Cancer9
Bioactivities of Dietary Polyphenols and Their Effects on Intestinal Microbiota9
The Use of Nanocarriers to Enhance the Anti-neuroinflammatory Potential of Dietary Flavonoids in Animal Models of Neurodegenerative Diseases: A Systematic Review9
MCM3AP-AS1: A LncRNA Participating in the Tumorigenesis of Cancer Through Multiple Pathways9
Natural Product-based Therapies for Inflammatory Bowel Disease: Targeting Key Signaling Pathways9
Lyophilization of Molecular Biology Reactions: A Review9
Meet the Editorial Board Member9
Pharmacological Modulation of Apoptosis and Autophagy in Pancreatic Cancer Treatment9
Recent Advances in Small Molecular PET Tracers for Pancreatic Cancer Diagnosis: Preclinical Stage9
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