Mini-Reviews in Medicinal Chemistry

Article	Citations
A Review on Chemical Structures and Biological Activities of Dopamine Derivatives from Medicinal Insects	92
Synthetic Approach to Potential Anticancer Benzimidazole Derivatives: A Review	58
Comprehensive Update on Synthetic Aspects of Bosentan Derivatives	54
Aptamers Against COVID-19: An Untested Opportunity	54
Synthesis of Phenothiazine Derivatives and their Diverse Biological Activities: A Review	50
Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes	49
Targeting Lysosomes: A Strategy Against Chemoresistance in Cancer	45
Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease	45
Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects	43
An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus	43
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease	43
Quinoxaline: A Chemical Moiety with Spectrum of Interesting Biological Activities	41
Current Perspective of Synthesis of Medicinally Relevant Benzothiazole based Molecules: Potential for Antimicrobial and Anti-Inflammatory Activities	40
The Role of IL-6 Released During Exercise to Insulin Sensitivity and Muscle Hypertrophy	32
Meet the Editorial Board Member	31
Meet the Editorial Board Member	31
Meet the Editorial Board Member	31
Meet the Editorial Board Member	30
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and Chemical Synthesis Approach	29
The most Recent Compilation of Reactions of Enaminone Derivatives with various Amine Derivatives to Generate Biologically Active Compounds	29
Chemotherapeutic Strategies for Combating Staphylococcus aureus Infections	29
Advances in Exercise Therapy in Hemodialysis: A Systematic Review	29
KRAS Pathway-based Therapeutic Approaches in Pancreatic Cancer	29
Bioactive Sulfonamides Derived from Amino Acids: Their Synthesis and Pharmacological Activities	28
Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome	27

Regulatory T Cells: Subtle and Promising Achilles' Heel of Psoriasis - Atherosclerosis Comorbidity	27
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells	24
Revolutionizing Playing with Skeleton Atoms: Molecular Editing Surgery in Medicinal Chemistry	24
The Pivotal Function of SLC16A1 and SLC16A1-AS1 in Cancer Progress: Molecular Pathogenesis and Prognosis	23
Meet the Editorial Board Member	23
Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin’s Lymphoma	23
A Review on Acridines as Antiproliferative Agents	23
Associate Editorial Board Members	23
Cinnamic Acid Derivatives: Recent Discoveries and Development Strategies for Alzheimer’s Disease	22
Meet the Section Editor	22
Recent Advancements in Strategies for Abnormal Protein Clearance in Alzheimer's Disease	21
Role of TBK1 Inhibition in Targeted Therapy of Cancer	21
Molecular Insights on the Therapeutic Effect of Selected Flavonoids on Diabetic Neuropathy	21
Inhibitors of Epigenetic Modulators as Therapeutic Alternatives for Cardiovascular Diseases	21
Natural Products with BACE1 and GSK3β Inhibitory Activity	20
The Role of MiR-29 in the Mechanism of Fibrosis	20
Research Progress in Alpha-fetoprotein-induced Immunosuppression of Liver Cancer	20
Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives	20
Medicinal Plants in Cancer Treatment: Contribution of Nuclear Factor- Kappa B (NF-kB) Inhibitors	19
Meet the Frontiers Section Editor	19
Overview of Piperine: Bioactivities, Total Synthesis, Structural Modification, and Structure-Activity Relationships	19
Pharmacological Efficacy and Safety of Glycyrrhiza glabra in the Treatment of Respiratory Tract Infections	19
Meet the Editorial Board Member	18
Meet the Editorial Board Member	18
AGAP2-AS1: An Indispensable lncRNA in Tumors	18
Breaking Barriers in Breast Cancer: Multi-Targeted Therapeutic Insights	17
Physicochemical Properties, Drug Delivery, and Tissue Engineering Applications of Neem Gum and Its Derivatives: A Comprehensive Review	17
Drug Solubilization by Surfactants: Experimental Methods and Theoretical Perspectives	17
Quinoline Derivatives as Promising Scaffolds for Antitubercular Activity: A Comprehensive Review	17
Recent Literature on the Synthesis of Thiazole Derivatives and their Biological Activities	16
Meet the Editorial Board Member	16
Roles of Accelerated Molecular Dynamics Simulations in Predictions of Binding Kinetic Parameters	16
Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings	16
Carbohydrazide Analogues: A Review of Synthesis and Biological Activities	16
Nimbolide: A Potential Phytochemical Agent in Multimodal Pancreatic Cancer Therapies	16
Natural Products, Synthesis, and Biological Activities of Quinolines (2020-2024)	15
Drug Repurposing: A Conduit to Unravelling Metabolic Reprogramming for Cancer Treatment	15
Recent Advances in the Development of Type 2 Sodium-Glucose Cotransporter Inhibitors for the Treatment of Type 2 Diabetes Mellitus	15
N-Methyl-D-Aspartate (NMDA)-Type Glutamate Receptors and Demyelinating Disorders: A Neuroimmune Perspective	15
Homometallic Polynuclear Rhodium Complexes in Anticancer Drug Development	15
MicroRNAs and Efferocytosis: Implications for Diagnosis and Therapy	15
Current Status of and Perspectives on Radiolabelled Ubiquicidin 29-41 Derivatives for Bacterial Infection Imaging	15
Meet the Editorial Board Member	14
Meet the Editorial Board Member	14
Quinoxaline 1,4-di-N-Oxide Derivatives: Are They Unselective or Selective Inhibitors?	14
Flavonoid-metal ion Complexes as Potent Anticancer Metallodrugs: A Comprehensive Review	14
Meet the Editor-in-Chief	14
A Comprehensive Review on Chemistry and Biology of Tafamidis in Transthyretin Amyloidosis	14
The Effects of Increased Glucose Level and Glycolysis on SARS CoV-2 Infection	14
The Art and Science of Antidiabetic Medications and Obesity Management	14

Meet the Editorial Board Member	14
Meet the Editorial Board Member	14
The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease	14
Development of Mycobacterium tuberculosis Enoyl Acyl Reductase (InhA) Inhibitors: A Mini-Review	14
Recent Updates on Sinularia Soft Coral	13
The Complex Roles of DNA Repair Pathways, Inhibitors, Hyperthermia, and Contact Inhibition in Cell Cycle Halts	13
Meet the Editorial Board Member	13
Comprehensive Insight into Green Synthesis Approaches, Structural Activity Relationship, and Therapeutic Potential of Pyrazolic Chalcone Derivative	13
Inhibitors Targeting Hepatitis C Virus (HCV) Entry	13
An Overview of Pyridazinone Analogs: Chemical and Pharmacological Potential	13
Meet the Editorial Board Member	13
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics	13
Effects of Urtica dioica on Metabolic Profiles in Type 2 Diabetes: A Systematic Review and Meta-analysis of Clinical Trials	13
Strategies in Taxol Development: A Review	13
Therapeutic Potentials of Aconite-like Alkaloids: Bioinformatics and Experimental Approaches	13
Meet the Editorial Board Member	13
Chemical Strategies Toward Prodrugs and Fluorescent Probes for Gasotransmitters	13
The Search for Antidotes Against Ricin	12
Chemistry, Analysis, and Biological Aspects of Daprodustat, A New Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor: A Comprehensive Review	12
A Critical Observation on the Design and Development of Reported Peptide Inhibitors of DENV NS2B-NS3 Protease in the Last Two Decades	12
In vivo Pharmacokinetic and ADMET Profiles of Synthetic Antimicrobial Peptides (AMPs)	12
The Application of the Pyrazole Structure in the Structural Modification of Natural Products	12
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review	12
The Situation of Small Molecules Targeting Key Proteins in combatting SARS-CoV-2: Synthesis, Metabolic Pathway, Mechanism of Action, and Potential Therapeutic Applications	12
Radical Releasing Anti-tuberculosis Agents and the Treatment of Mycobacterial Tuberculosis Infections - An Overview	12
A Therapeutic Journey of Potential Drugs Against COVID-19	12
Therapeutic Approaches for the Treatment of Interstitial Lung Disease: An Exploratory Review on Molecular Mechanisms	12
Meet the Editorial Board Member	12
Second-line Therapy for Helicobacter Pylori Eradication: State of the Art	12
Energy Metabolism Behavior and Response to Microenvironmental Factors of the Experimental Cancer Cell Models Differ from that of Actual Human Tumors	12
Nuclei-targeted Therapeutic Delivery: A Novel Concept for the Treatment of Cancer	12
The Therapeutic Potential and Molecular Mechanisms Underlying the Neuroprotective Effects of Sativex® - A Cannabis-derived Spray	12
New Insights into the Modifications and Bioactivities of Indole-3- Carboxaldehyde and its Derivatives as a Potential Scaffold for Drug Design: A Mini-Review	11
Recent Advancements and SAR Studies of Synthetic Coumarins as MAO-B Inhibitors: An Updated Review	11
Melatonin and Related Compounds as Antioxidants	11
Antioxidant Activity of 1,2,4-Triazole and its Derivatives: A Mini-Review	11
The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)	11
Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review	11
Recent Insights of Metformin on Hepatocellular Carcinoma (HCC)	11
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases	11
Narrative Review of the Pharmacodynamics, Pharmacokinetics, and Toxicities of Illicit Synthetic Cannabinoid Receptor Agonists	11
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications	11
Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions	11
Anthriscus sylvestris: An overview on Bioactive Compounds and Anticancer Mechanisms from a Traditional Medicinal Plant to Modern Investigation	11
Evaluation of Melatonin and its Nanostructures Effects on Skin Disorders Focused on Wound Healing	11
Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry	11
Meet the Editorial Board Member	10
Research Progress in Mutagenesis Techniques for Aspergillus fumigatus and the Biological Activities of Fumagillin	10
Cardiovascular Effects of Ruthenium Complexes: A Potential Therapeutic Tool in Hypertension and Myocardial Injury	10
Agent in Urgent Need of Clinical Practice: Corilagin	10
Some Scaffolds as Anti-leishmanial Agents: A Review	10
Meet the Editorial Board Member	10
Protective Effect of Plumeria Pudica Latex Proteins on Intestinal Mucositis Induced by 5-Fluorouracil	10
Recent Development of CXCR4-Targeted Nuclear Medicine Research in Adrenocortical Tumors	10
Anticancer Potential of Naringenin, Biosynthesis, Molecular Target, and Structural Perspectives	10
Peroxisome Proliferator-activated Receptor-γ As A Novel and Promising Target For Treating Cancer Via Regulation of Inflammation: A Brief Review	10
Synthesis and Biological Properties of Isatin-indole Hybrids: A Review	10
Nicotinamide Adenine Dinucleotide in the Development and Treatment of Cardiac Remodeling and Aging	10
Aloe-emodin: Progress in Pharmacological Activity, Safety, and Pharmaceutical Formulation Applications	10
Chromone, A Privileged Scaffold in Drug Discovery: Developments in the Synthesis and Bioactivity	10
A Short Review on Glucogallin and its Pharmacological Activities	10
Targeting Bcl-2 with Indole Scaffolds: Emerging Drug Design Strategies for Cancer Treatment	10
Modulation of Long Non-coding RNAs by Different Classes of Secondary Metabolites from Plants: A Mini-review on Antitumor Effects	10
Advances in Biocatalytic Synthesis, Pharmacological Activities, Pharmaceutical Preparation and Metabolism of Ginsenoside Rh2	10
Meet the Co-Editor	9
Recent Advances in Small Molecular PET Tracers for Pancreatic Cancer Diagnosis: Preclinical Stage	9
Levothyroxine and Non-alcoholic Fatty Liver Disease: A Mini Review	9
Natural Product-based Therapies for Inflammatory Bowel Disease: Targeting Key Signaling Pathways	9
Biological Activities of Morita-Baylis-Hillman Adducts (MBHA)	9
Meet the Editorial Board Member	9
Natural and Synthetic Phosphodiesterase Inhibitors in 2023: an Update on the Impact on Neurological and Psychiatric Conditions	9
Fungal Endophytes: A Storehouse of Bioactive Compounds	9
Recent Studies on the Pharmacological Activities and Structural Modifications of Compound-K	9
MCM3AP-AS1: A LncRNA Participating in the Tumorigenesis of Cancer Through Multiple Pathways	9
Cathepsin B-A Neuronal Death Mediator in Alzheimer’s Disease Leading to Neurodegeneration	9
Systematic Review of the Serotonergic System in the Pathophysiology of Severe Dengue: The Theory of Thrombocytopenia and Vascular Extravasation	9
The Indispensable Roles of GMDS and GMDS-AS1 in the Advancement of Cancer: Fucosylation, Signal Pathway and Molecular Pathogenesis	9
Pharmacological Modulation of Apoptosis and Autophagy in Pancreatic Cancer Treatment	9
Bioactivities of Dietary Polyphenols and Their Effects on Intestinal Microbiota	9
Lyophilization of Molecular Biology Reactions: A Review	9

Dendrobine: A neuroprotective Sesquiterpenic Alkaloid for the Prevention and Treatment of Diseases: A Review	9
Meet the Editor in Chief	9
Comparative Review of Effects of Pien Tze Huang and AnGong NiuHuang Pill and their Potential on Treatment of Central Nervous System Diseases	8
Meet the Editorial Board Member	8
Meet the Associate Editorial Board Member	8
Alzheimer's Disease and Cancer: Common Targets	8
Mitochondria as a Therapeutic Target in Metabolic Disorders	8
An Updated and Focused Review on Heterocyclic Inhibitors for SARSCoV and SARS-CoV-2 3CLpro	8
The Use of Nanocarriers to Enhance the Anti-neuroinflammatory Potential of Dietary Flavonoids in Animal Models of Neurodegenerative Diseases: A Systematic Review	8
Acknowledgements to Reviewers	8
The Emergence of N. sativa L. as a Green Antifungal Agent	8
Role of Caffeine in the Age-related Neurodegenerative Diseases: A Review	8
The Role of Renin-Angiotensin System in Diabetic Nephropathy: An Update	8
LncRNA DSCAM-AS1: A Pivotal Therapeutic Target in Cancer	8
Meet the Associate Editorial Board Member	8
Acknowledgement to Reviewers	8
Exploring Tetrahydroisoquinoline (THIQ) Scaffold as Therapeutic Modulators of Sigma Receptors	8
Research Progress of Tamarixetin and its Glycosides	8
A Concise and Useful Guide to Understand How Alpha1 Adrenoceptor Antagonists Work	7
Promising Enzymes for Inhibitors Development Against COVID-19	7
ZFPM2-AS1: An Oncogenic Long Non-coding RNA in Multiple Cancer Types	7
Pyridine Moiety: An Insight into Recent Advances in the Treatment of Cancer	7
Dietary Intake of Hydrolyzable Tannins and Condensed Tannins to Regulate Lipid Metabolism	7
Biodegradable Polymers and their Applications: A Review	7
The Role of Epigenetic Mechanisms in Autoimmune, Neurodegenerative, Cardiovascular, and Imprinting Disorders	7
A New Mode of Thinfilm and Nanofiber for Burst Release of the Drug for Alzheimer Disease; A Complete Scenario from Dispersible Polymer to Formulation Methodology	7
Exploring Genetic Silencing: RNAi and CRISPR-Cas Potential against Drug Resistance in Malaria	7
Mitochondrial Proteins as Metabolic Biomarkers and Sites for Therapeutic Intervention in Primary and Metastatic Cancers	7
Therapeutic Potential of Thiophene Compounds: A Mini-Review	7
Recent Advances in Fluorescent Probes for G-quadruplex DNAs / RNAs	7
Meet the Section Editor	7
1,3,5-Triazine: Recent Development in Synthesis of its Analogs and Biological Profile	7
Gastrointestinal, Liver, Pancreas, Oral and Psychological Long-term Symptoms of COVID-19 After Recovery: A Review	7
Phage-choline Kinase Inhibitor Combination to Control Pseudomonas aeruginosa: A Promising Combo	7
Meet the Editorial Board Member	7
The Roles, Mechanisms, and Clinical Significance of Long Non-coding RNA MSC-AS1 in Cancer	7
Mini-Review on Vitamin D in Pediatric Population and its Role in Respiratory and Atopic Disorders	7
Osthole: Synthesis, Structural Modifications, and Biological Properties	7
Developments in the Antitumor Activity, Mechanisms of Action, Structural Modifications, and Structure-Activity Relationships of Steroidal Saponins	7
Effects of Green Tea (−)-Epigallocatechin-3-Gallate (EGCG) on Cardiac Function - A Review of the Therapeutic Mechanism and Potentials	7
Antidiabetic Properties of Dietary Chrysin: A Cellular Mechanism Review	6
Preface	6
Molecular Targets for Chalcones in Antileishmanial Drug Discovery	6
Research Progress of Diterpenoids with Potential Antidiabetic Activity	6
Chitosan: Applications in Drug Delivery System	6
Cyclin-Dependent Kinase 4/6 Inhibitors Against Breast Cancer	6
In silico Approaches for Exploring the Pharmacological Activities of Benzimidazole Derivatives: A Comprehensive Review	6
Emerging Role of Dendrobium Orchid Plants in Diabetes: Phytochemistry Aspects, SAR, and Therapeutic Potential	6
Nuclear Medicine Application of Pentixafor/Pentixather Targeting CXCR4 for Imaging and Therapy in Related Disease	6
Recent Development of DNA Gyrase Inhibitors: An Update	6
Anti-Tubercular Activity of Pyrazinamide Conjugates: Synthesis and Structure-Activity Relationship Studies	6
Recent Advances in PI3 Kinase Inhibitors: Anticancer Activities and Structure-Activity Relationships	6
Recent Progress of Bioactivities, Mechanisms of Action, Total Synthesis, Structural Modifications and Structure-activity Relationships of Indole Derivatives: A Review	6
MiRNAs: Emerging Agents for Therapeutic Effects of Polyphenols on Ovarian Cancer	6
Withdrawal: Advances in Development of Drugs for Chronic Myelogenous Leukemia	6
Acknowledgements to Reviewers	6
Nano-biotechnology and its Innovative Perspective in Diabetes Management	6
A Review and Meta-analysis on Trastuzumab Resistance in Patients with HER2+ Breast Cancer	6
Insight in Quinazoline-based HDAC Inhibitors as Anti-cancer Agents	6
SARS-CoV-2 Infections, Impaired Tissue, and Metabolic Health: Pathophysiology and Potential Therapeutics	6
The Progress of Small Molecule Targeting BCR-ABL in the Treatment of Chronic Myeloid Leukemia	6
Meet the Editorial Board Member	6
Meet the Section Editor	6
Recent Advances in the Therapeutic Prospective of Heterocyclic Derivatives as COX-2 Inhibitors (2019-Present)	5
Perspectives on Agmatine Neurotransmission in Acute and Chronic Stressrelated Conditions	5
Potential of MAO-B Inhibitors with Multi-Target Inhibition and Antioxidant Properties for the Treatment of Neurodegenerative Disorders	5
Meet the Editorial Board Member	5
Advances in the Development of Non-Structural Protein 1 (NsP1) Inhibitors for the Treatment of Chikungunya Virus Infection	5
An In Silico Approach to Exploring the Antinociceptive Biological Activities of Linalool and its Metabolites	5
Meet the Editorial Board Member	5
Tanshinone IIA Against Cerebral Ischemic Stroke and Ischemia- Reperfusion Injury: A Review of the Current Documents	5
Small-Molecule Drugs in Immunotherapy	5
Optical Biosensors: A Comprehensive Review of Their Applications in Photoplethysmography, Environmental Monitoring, and Medical Diagnostics	5
Methyl-linked Pyrazoles: Synthetic and Medicinal Perspective	5
The Immune Response to SARS-CoV-2: Mechanisms, Aging, Sequelae, and Vaccines	5
Synthetic Attempts Towards Eminent Anti-viral Candidates of SARS-CoV	5
An Outline on Benzimidazole Containing Marketed Drugs with Proton Pump Inhibitor and H1 Receptor Antagonist Activities	5
Anticancer Drug Discovery By Structure-Based Repositioning Approach	5
Meet the Editorial Board Member	5
Research Progress on the Natural Product Aloperine and Its Derivatives	5
Advances in Pyrazole Based Scaffold as Cyclin-dependent Kinase 2 Inhibitors for the Treatment of Cancer	5
Innovative Theranostics Strategies in the Fight Against Lung Cancer	5
Preface	5
Tuberculosis, BCG Vaccination, and COVID-19: Are They Connected?	5
Pharmaceutical Studies on Piperazine-based Compounds Targeting Serotonin Receptors and Serotonin Reuptake Transporters	5
Nature-Derived Hit, Lead, and Drug-Like Small Molecules: Current Status and Future Aspects Against Key Target Proteins of Coronaviruses	5
Research and Progress of Probucol in Nonalcoholic Fatty Liver Disease	5
Exploring the Potential of Anacardic Acid, its Natural and Synthetic Analogues, and Nanoformulations as a Potential Antibacterial Agent, including Multidrug-Resistant Bacteria: A Comprehensive Review	5
The Recent Developments of ADCs with the Tubulysins as the Payloads	5
Triterpenoid Compounds and their Derivatives: Emerging Pharmacological Agents for Arthritis Treatment	4
An Overview of Treatment Guidelines and Methods of Synthesis of Drugs Used in Leprosy Chemotherapy	4
Polychlorinated Biphenyls: A Review of Recent Updates on Food Safety and Environmental Monitoring, Health and Toxicological Implications, and Analysis	4
Discovery of Polo-like Kinase 4 Inhibitors for the Treatment of Cancer: A Mini Patent Review	4
Value of Contrast-enhanced Magnetic Resonance Imaging (MRI) in the Diagnosis of Breast Cancer	4
Antiviral Activity of Pyrimidine Containing Compounds: Patent Review	4