OOIR: Observatory of International Research

Papers

(The TQCC of Current Drug Targets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Current Research Trends in Cytokine Storm: A Scientometric Study	37
Meet the Editorial Board Member	36
Cell Entry and Unusual Replication of SARS-CoV-2	34
Meet the Editorial Board Member	30
SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies	29
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges	26
Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment	24
Retracted: Meet the Editorial Board Member	24
Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis	23
Metformin: A Promising Antidiabetic Medication for Cancer Treatment	23
The Development of the Combination Drug Leukovir® Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review	22
The Marburg Virus Outbreak in West Africa	22
Use of Total Parenteral Nutrition (TPN) as a Vehicle for Drug Delivery	21
Meet the Editorial Board Member	21
Meet the Regional Editor	21
Xerostomia: Advances and Challenges in Drug Development	20
An Updated Review for the Diabetic Wound Healing Systems	20
Current Perspectives of Healthy Mitochondrial Function for Healthy Neurons	20
Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach	20
Regulation of Tumor Immune Microenvironment by Sphingolipids and Lysophosphatidic Acid	19
Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications	19
Venom of Viperidae: A Perspective of its Antibacterial and Antitumor Potential	19
Targeting Neurodegeneration: The Emerging Role of Hybrid Drugs	19
An Overview of Research Advances in Oncology Regarding the Transcription Factor ATF4	18
Meet the Editorial Board Member	18

Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia	18
COVID-19 Induces Cytokine Storm and Dysfunctional Hemostasis	17
Lipid-based Nanocarriers Loaded with Taxanes for the Management of Breast Cancer: Promises and Challenges	17
Bile Acid Application in Cell-Targeting for Molecular Receptors in Relation to Hearing: A Comprehensive Review	17
Insights into the Mechanism of the Therapeutic Potential of Herbal Monoamine Oxidase Inhibitors in Neurological Diseases	17
Targets Involved in the Pharmacology of Bothrops Snakebite: Statu Quo and Future Perspectives	17
An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer	17
Diabetic Nephropathy: Pathogenesis to Cure	15
The Role of Leukocyte Immunoglobulin-Like Receptors Focusing on the Therapeutic Implications of the Subfamily B2	15
Acknowledgements to Reviewers	15
Lipidomics as Tools for Finding Biomarkers of Intestinal Pathology: From Irritable Bowel Syndrome to Colorectal Cancer	15
The Novel Use of Lipids as Diagnostic Tools and Therapeutics in Cancer: Recent Insights and Challenges	15
Research Progress of PARP Inhibitor Monotherapy and Combination Therapy for Endometrial Cancer	15
RMNet: An RNA m6A Cross-species Methylation Detection Method for Nanopore Sequencing	15
Meet the Editorial Board Member	15
Rho Kinase (ROCK) Inhibitors for the Treatment of Glaucoma	14
Does the Grape Products Intake has an Effect on Body Weight in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials	14
Implications of microRNAs in the Pathogenesis of Atherosclerosis and Prospects for Therapy	14
IL-17 Antagonists as a Promising Therapeutic Modality for Hidradenitis Suppurativa	14
Exploring the Efficient Natural Products for the Therapy of Parkinson’s Disease via Drosophila Melanogaster (Fruit Fly) Models	14
A Comprehensive Insight on Pharmaceutical Co-crystals for Improvement of Aqueous Solubility	13
ClpP Peptidase as a Plausible Target for the Discovery of Novel Antibiotics	13
Advanced Drug Delivery System for Management of Chronic Diabetes Wound Healing	13
Innovations in Antimalarial Drug Discovery: New Targets and Leads	13
Multi-target Compounds against Trypanosomatid Parasites and Mycobacterium tuberculosis	12
Potential Targets in Constipation Research: A Review	12
Targeting Creatine and Creatine Kinase in Cancer: Exploring Potential Therapeutic Strategies	12
Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target	12
ACE2 as a Key Target for Treatment of COVID-19 Related Cardiovascular Diseases: Current Progress and Prospect	12
Phytovesicular Nanoconstructs for Advanced Delivery of Medicinal Metabolites: An In-Depth Review	12
Prospection of Microfluidics for Local Drug Delivery	12
Dysregulation of Lysyl Oxidases Expression in Diabetic Nephropathy and Renal Cell Carcinoma	12
Transcending Molecules: Paving the Way from Lab to Life in Drug Transport Innovation	12
Recent Advances in Biomedical Applications of Mannans and Xylans	11
RAAS Overactivation and Mitochondrial Damage Signaling as Key Players in Lethal COVID-19	11
Impaired Quality Control of Mitochondria Underlying the Pathogenesis of Alzheimer's Disease	11
MiRNAs Overexpression and Their Role in Breast Cancer: Implications for Cancer Therapeutics	11
Effect of Rotenone on the Neurodegeneration among Different Models	11
Recent Advances in the Development of Alpha-Glucosidase and Alpha-Amylase Inhibitors in Type 2 Diabetes Management: Insights from In silico to In vitro Studies	11
A Review on the Current Status of Homeopathy in the Clinical Manage-ment of Cancer	10
Targeted Covalent Inhibition: A Prospective Way to Develop Novel HSP90 C-terminal Inhibitor	10
Proteasome as a Drug Target in Trypanosomatid Diseases	10
An Exploratory Review on the Hypoglycemic Action of Unani Anti-diabetic Drugs via Possible Modulation of Gut Microbiota	10
Combination Therapy as a Strategy to Control Infections Caused by Multi-resistant Bacteria: Current Review	10
Role of γ-Secretase Inhibitors for the Treatment of Diverse Disease Conditions through Inhibition of Notch Signaling Pathway	10
Co-Crystallization: A Novel Technique to Improvise the Pharmaceutical Characteristics of API’s	10
Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies	10
Meet the Editorial Board Member	10
Signaling Dynamics in Osteogenesis: Unraveling Therapeutic Targets for Bone Generation	10
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization	10

Exploring the SARS-Cov-2 Main Protease (Mpro) and RdRp Targets by Updating Current Structure-based Drug Design Utilizing Co-crystals to Combat COVID-19	10
Emerging Threats and Challenges of Monkeypox Virus: Exploration and Sensitivity	10
Emerging Role of Circular RNAs in Kidney Diseases in Nephrology	10
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead	9
Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials	9
Nanoformulations - Insights Towards Characterization Techniques	9
Anti-inflammatory Potential of GSK-3 Inhibitors	9
Diabetic Wound Healing: Factors, Mechanisms, and Treatment Strategies Using Herbal Components	8
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment	8
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa	8
Role of GSK-3 in Cardiac Health: Focusing on Cardiac Remodeling and Heart Failure	8
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy	8
Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials	8
Multitarget Compounds for Neglected Diseases: A Review	8
A Comprehensive Review on Chrysin: Emphasis on Molecular Targets, Pharmacological Actions and Bio-pharmaceutical Aspects	7
Superoxide Dismutase Inhibitors against Malaria, Leishmaniasis, and Chagas Disease: Systematic Review	7
Precision Targeting of BET Proteins - Navigating Disease Pathways, Inhibitor Insights, and Shaping Therapeutic Frontiers: A Comprehensive Review	7
Differential Drug Permeability across Biofilms	7
Meet the Associate Editorial Board Member	7
3D Printing Technology in Pharmaceutical Dosage Forms: Advantages and Challenges	7
Acknowledgements to Reviewers	7
A Review on Development and Characterization of a Cost-effective Targeted Quality-driven Antimalarial Product with an Emphasis on Phytosomes	7
Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection	7
Proteases and Osteoporosis: A Comprehensive Review of Their Role in Bone Health	7
Cerebrovascular Complications of Diabetes: SGLT-2 Inhibitors as a Promising Future Therapeutics	7
Vaccine for Targeted Therapy of Lung Cancer: Advances and Developments	7
Sodium-glucose Cotransporter 2 Inhibitors and Pathological Myocardial Hypertrophy	7