Current Drug Targets

Article	Citations
Current Research Trends in Cytokine Storm: A Scientometric Study	154
Meet the Editorial Board Member	44
Cell Entry and Unusual Replication of SARS-CoV-2	35
The Development of the Combination Drug Leukovir® Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review	31
Meet the Editorial Board Member	30
SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies	30
Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment	28
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges	27
Retracted: Meet the Editorial Board Member	25
The Marburg Virus Outbreak in West Africa	25
Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis	24
Metformin: A Promising Antidiabetic Medication for Cancer Treatment	23
Meet the Regional Editor	22
Meet the Editorial Board Member	21
Antibiotic Adjuvants: A Promising Approach to Combat Multidrug Resistant Bacteria	21
Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications	20
Regulation of Tumor Immune Microenvironment by Sphingolipids and Lysophosphatidic Acid	20
An Updated Review for the Diabetic Wound Healing Systems	20
Venom of Viperidae: A Perspective of its Antibacterial and Antitumor Potential	19
Xerostomia: Advances and Challenges in Drug Development	19
Post-menopausal Osteoporosis and Probiotics	19
Targeting Neurodegeneration: The Emerging Role of Hybrid Drugs	19
Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia	18
Current Perspectives of Healthy Mitochondrial Function for Healthy Neurons	18
Meet the Editorial Board Member	18

Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach	18
Use of Total Parenteral Nutrition (TPN) as a Vehicle for Drug Delivery	18
Nanotechnology Based Approach for Hepatocellular Carcinoma Targeting	17
Research Progress of PARP Inhibitor Monotherapy and Combination Therapy for Endometrial Cancer	16
Preclinical Drug Discovery in Colorectal Cancer: A Focus on Natural Compounds	16
Bile Acid Application in Cell-Targeting for Molecular Receptors in Relation to Hearing: A Comprehensive Review	16
An Overview of Research Advances in Oncology Regarding the Transcription Factor ATF4	16
Lipidomics as Tools for Finding Biomarkers of Intestinal Pathology: From Irritable Bowel Syndrome to Colorectal Cancer	16
Targets Involved in the Pharmacology of Bothrops Snakebite: Statu Quo and Future Perspectives	15
An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer	15
Insights into the Mechanism of the Therapeutic Potential of Herbal Monoamine Oxidase Inhibitors in Neurological Diseases	15
COVID-19 Induces Cytokine Storm and Dysfunctional Hemostasis	15
Diabetic Nephropathy: Pathogenesis to Cure	15
Lipid-based Nanocarriers Loaded with Taxanes for the Management of Breast Cancer: Promises and Challenges	15
Acknowledgements to Reviewers	14
The Novel Use of Lipids as Diagnostic Tools and Therapeutics in Cancer: Recent Insights and Challenges	14
Meet the Editorial Board Member	14
Meet Our Editorial Board Member	13
Rho Kinase (ROCK) Inhibitors for the Treatment of Glaucoma	13
A Comprehensive Insight on Pharmaceutical Co-crystals for Improvement of Aqueous Solubility	13
ClpP Peptidase as a Plausible Target for the Discovery of Novel Antibiotics	13
Innovations in Antimalarial Drug Discovery: New Targets and Leads	13
The Role of Leukocyte Immunoglobulin-Like Receptors Focusing on the Therapeutic Implications of the Subfamily B2	13
Does the Grape Products Intake has an Effect on Body Weight in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials	13
Implications of microRNAs in the Pathogenesis of Atherosclerosis and Prospects for Therapy	13
Recent Advances in Biomedical Applications of Mannans and Xylans	12
Exploring the Efficient Natural Products for the Therapy of Parkinson’s Disease via Drosophila Melanogaster (Fruit Fly) Models	12
Impaired Quality Control of Mitochondria Underlying the Pathogenesis of Alzheimer's Disease	12
Advanced Drug Delivery System for Management of Chronic Diabetes Wound Healing	12
Multi-target Compounds against Trypanosomatid Parasites and Mycobacterium tuberculosis	12
Prospection of Microfluidics for Local Drug Delivery	12
Recent Advances in the Development of Alpha-Glucosidase and Alpha-Amylase Inhibitors in Type 2 Diabetes Management: Insights from In silico to In vitro Studies	11
Transcending Molecules: Paving the Way from Lab to Life in Drug Transport Innovation	11
Phytovesicular Nanoconstructs for Advanced Delivery of Medicinal Metabolites: An In-Depth Review	11
Role of γ-Secretase Inhibitors for the Treatment of Diverse Disease Conditions through Inhibition of Notch Signaling Pathway	11
ACE2 as a Key Target for Treatment of COVID-19 Related Cardiovascular Diseases: Current Progress and Prospect	11
Potential Targets in Constipation Research: A Review	11
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization	11
Effect of Rotenone on the Neurodegeneration among Different Models	11
Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target	11
Dysregulation of Lysyl Oxidases Expression in Diabetic Nephropathy and Renal Cell Carcinoma	11
MiRNAs Overexpression and Their Role in Breast Cancer: Implications for Cancer Therapeutics	10
A Critical Review of Second-Generation Anti-EGFR Monoclonal Antibodies in Metastatic Colorectal Cancer	10
A Review on the Current Status of Homeopathy in the Clinical Manage-ment of Cancer	10
Proteasome as a Drug Target in Trypanosomatid Diseases	10
Emerging Role of Circular RNAs in Kidney Diseases in Nephrology	10
Signaling Dynamics in Osteogenesis: Unraveling Therapeutic Targets for Bone Generation	10
Combination Therapy as a Strategy to Control Infections Caused by Multi-resistant Bacteria: Current Review	10
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead	9
An Exploratory Review on the Hypoglycemic Action of Unani Anti-diabetic Drugs via Possible Modulation of Gut Microbiota	9

Anti-inflammatory Potential of GSK-3 Inhibitors	9
Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies	9
Targeted Covalent Inhibition: A Prospective Way to Develop Novel HSP90 C-terminal Inhibitor	9
Co-Crystallization: A Novel Technique to Improvise the Pharmaceutical Characteristics of API’s	9
Emerging Threats and Challenges of Monkeypox Virus: Exploration and Sensitivity	9
Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials	9
Meet the Editorial Board Member	9
Exploring the SARS-Cov-2 Main Protease (Mpro) and RdRp Targets by Updating Current Structure-based Drug Design Utilizing Co-crystals to Combat COVID-19	9
Nanoformulations - Insights Towards Characterization Techniques	9
Target Genetic Abnormalities for the Treatment of Colon Cancer and Its Progression to Metastasis	8
A Comprehensive Review on Chrysin: Emphasis on Molecular Targets, Pharmacological Actions and Bio-pharmaceutical Aspects	8
Role of GSK-3 in Cardiac Health: Focusing on Cardiac Remodeling and Heart Failure	8
Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials	8
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy	8
The Emergence of Immune-checkpoint Inhibitors in Colorectal Cancer Therapy	8
Meet Our Editorial Board Member	8
Proteases and Osteoporosis: A Comprehensive Review of Their Role in Bone Health	8
3D Printing Technology in Pharmaceutical Dosage Forms: Advantages and Challenges	8
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa	8
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment	8
Multitarget Compounds for Neglected Diseases: A Review	8
Diabetic Wound Healing: Factors, Mechanisms, and Treatment Strategies Using Herbal Components	8
Cerebrovascular Complications of Diabetes: SGLT-2 Inhibitors as a Promising Future Therapeutics	8
Colorectal Cancer Epidemiology: Recent Trends and Impact on Outcomes	8
Meet the Associate Editorial Board Member	7
Superoxide Dismutase Inhibitors against Malaria, Leishmaniasis, and Chagas Disease: Systematic Review	7
Acknowledgements to Reviewers	7
Sodium-glucose Cotransporter 2 Inhibitors and Pathological Myocardial Hypertrophy	7
Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection	7
Vaccine for Targeted Therapy of Lung Cancer: Advances and Developments	7
Anti-VEGF Mediated Immunomodulatory Role of Phytochemicals: Scientific Exposition for Plausible HCC Treatment	7
Precision Targeting of BET Proteins - Navigating Disease Pathways, Inhibitor Insights, and Shaping Therapeutic Frontiers: A Comprehensive Review	7
The Resurgence of H3N2 in India: Is it Life-threatening?	6
Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System	6
Differential Drug Permeability across Biofilms	6
Meet the Editorial Board Member	6
An Update on the Emerging Role of Wnt/β-catenin, SYK, PI3K/AKT, and GM-CSF Signaling Pathways in Rheumatoid Arthritis	6
Recent Advances in the Discovery of GSK-3 Inhibitors from Synthetic Origin in the Treatment of Neurological Disorders	6
A Review on Development and Characterization of a Cost-effective Targeted Quality-driven Antimalarial Product with an Emphasis on Phytosomes	6
Cell-penetrating Peptide-mediated Nanovaccine Delivery	6
Anti-Degenerative Effect of Melatonin on Intervertebral Disc: Protective Contribution against Inflammation, Oxidative Stress, Apoptosis, and Autophagy	6
Beneficial Outcomes of Cancer Therapeutic Modalities Based on Targeting Apoptosis	6
Anti-VEGF Therapy in Myopic CNV	6
The Mechanistic Role of Different Mediators in the Pathophysiology of Nephropathy: A Review	6
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders	6
Endemic and Indigenous Plants from Mascarene Islands with Antiviral Propensities	5
Meet the Editorial Board Member	5
Meet the Regional Editor	5
Endogenous Enzyme-responsive Nanoplatforms for Anti-tumor Therapy	5
Roadmap to Pyruvate Kinase M2 Modulation - A Computational Chronicle	5
Polypharmacology-Driven Discovery and Design of Highly Selective, Dual and Multitargeting Inhibitors of Mycobacterium tuberculosis - A Review	5
An Update On Proficiency of Voltage-gated Ion Channel Blockers in the Treatment of Inflammation-associated Diseases	5
Two Decades Rituximab Therapy in Anti-Neutrophil Cytoplasmic Antibody Associated Vasculitis	5
Molecular Modeling Targeting Transmembrane Serine Protease 2 (TMPRSS2) as an Alternative Drug Target Against Coronaviruses	5
Deciphering Neuroprotective Effect of Rosmarinus officinalis L. (syn. Salvia rosmarinus Spenn.) through Preclinical and Clinical Studies	5
Targeted Regulation of Intracellular Signal Transduction: A New Paradigm for Stimulation of Neurogenesis in Alzheimer's Disease	5
Bidirectional Relations Between Anxiety, Depression, and Cancer: A Review	5
Directing Hypoxic Tumor Microenvironment and HIF to Illuminate Cancer Immunotherapy's Existing Prospects and Challenges in Drug Targets	5
Polymer-dendrimer Hybrids as Carriers of Anticancer Agents	5
Meet the Editorial Board Member	5
Cellular Therapeutics for Chronic Wound Healing: Future for Regenerative Medicine	5
Endogenous Ligands of TLR4 in Microglia: Potential Targets for Related Neurological Diseases	4
NLRP3: A Promising Therapeutic Target for Inflammatory Bowel Disease	4
Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection	4
LncRNA HAGLROS: A Vital Oncogenic Propellant in Various Human Cancers	4
A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease	4
TL1A: A New Potential Target in the Treatment of Inflammatory Bowel Disease	4
A Review on CRISPR-mediated Epigenome Editing: A Future Directive for Therapeutic Management of Cancer	4
Gastrointestinal System: COVID-19 and Potential Mechanisms Associated with Coagulopathy	4
Recent Advancement in Topical Drug Delivery for Psoriasis: Clinical Pertinence and Potential Market	4
A Review on the Recent Advancements and Artificial Intelligence in Tablet Technology	4
Long Non-coding RNA Therapeutics: Recent Advances and Challenges	4
Parkinson’s Disease: A Current Perspectives on Parkinson’s Disease and Key Bioactive Natural Compounds as Future Potential Drug Candidates	4
An Insight Into Mitochondrial Dysfunction and its Implications in Neurological Diseases	4
Natural Bioactive Compounds as Emerging Therapeutic Molecules Against Breast Cancer: Emphasis on the Role of Phytoestrogens	4
Nanocarriers’- An efficient drug delivery system for neurodegenerative disorders including Alzheimer’s, Parkinson’s, Huntington, Amyotrophic lateral sclerosis and associated risk of nanocarriers, futu	4
Nano Architect-Based Targeted Delivery Systems for Diabetic Nephropathy: A Review	4
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment	4
Phytoconstituents-Based Nanotherapeutic Approach for the Effective Management of Joint Inflammatory Condition: Arthritis	4
Hybrid-Compounds Against Trypanosomiases	4

Nanocarriers for Photodynamic Therapy Intended to Cutaneous Tumors	4
Comparative Analysis of Circular RNAs Expression and Function between Aortic and Intracranial Aneurysms	4
An Insight into Diverse Activities and Targets of Flavonoids	4
Small-molecule Antiviral Agents in Ongoing Clinical Trials for COVID-19	4
Meet the Editorial Board Member	4
Strategies and Therapies for Wound Healing: A Review	4
Antiviral Potential of Traditional Unani Medicine with Special Emphasis on Dengue: A Review	4
Biomimetic Drug Delivery Systems Oriented by Biological Function in Tumor Targeting	4
Mesenchymal Stem Cells and Cancer Stem Cells: An Overview of Tumor- Mesenchymal Stem Cell Interaction for Therapeutic Interventions	4
Recent Advances in Psoriasis Therapy: Trends and Future Prospects	4
The Therapeutic Potential of Targeting Hsp90-Cdc37 Interactions in Several Diseases	4
Adenosine Dysfunction in Epilepsy and Associated Comorbidities	3
A Comprehensive Review on Liver Targeting: Emphasis on Nanotechnology- based Molecular Targets and Receptors Mediated Approaches	3
Promising Protective Effects of Chrysin in Cardiometabolic Diseases	3
Recent Progress and Challenges in Clinical Translation of Nanomedicines in Diagnosis and Treatment of Lung Cancer	3
Deciphering the Role of Pyroptosis Impact on Cardiovascular Diseases	3
Meet the Editorial Board Member	3
Extracellular Vesicles from Stromal Vascular Fraction of Human Adipose Tissue in the Development of Non-antibiotic Therapy	3
Therapeutic Potential of Targeting Transforming Growth Factor-beta (TGF-β) and Programmed Death-ligand 1 (PD-L1) in Pancreatic Cancer	3
Strategies for Treatment of Thyroid Cancer	3
Deferoxamine Interference in Fibro-inflammation: Additional Action in Control of Obese Adipose Tissue Dysfunction	3
Redox Interactions in Chemo/Radiation Therapy-induced Lung Toxicity; Mechanisms and Therapy Perspectives	3
GSK-3 Inhibitors: A New Class of Drugs for Alzheimer’s Disease Treatment	3
GSK-3 Inhibitors in the Regulation and Control of Colon Carcinoma	3
Role of Mitochondrial Heat-shock Proteins and Immunophilins in Neuro Degenerative Diseases	3
Comprehensive Analysis of Omicron Subvariants: EG.5 Rise, Vaccination Strategies, and Global Impact	3
Meet the Editorial Board Member	3
Promising New Targets for the Treatment of Infections Caused by Acinetobacter baumannii: A Review	3
Crucial Role of microRNAs as New Targets for Amelogenesis Disorders Detection	3
Antiobesity Drug Discovery Research: In vitro Models for Shortening the Drug Discovery Pipeline	3
Potential Target of CDK6 Signaling Pathway for Cancer Treatment	3
Molecular Complex of HSIM-loaded Polymeric Nanoparticles: Potential Carriers in Osteoporosis	3
Adipocyte Fatty Acid Binding Protein (A-FABP) as a Potential New Therapeutic Target for the Treatment of Obesity - Associated Cancers	3
Microbial Synthesis of Gold Nanoparticles and their Application	3
Quorum Sensing and its Inhibition in Pseudomonas aeruginosa: Molecular Targets and Mode of Action	3
Meet the Section Editor	3
The Clinical Safety and Efficacy of Targeted PD-L1 Therapy with Durvalumab in Solid Tumors	3
Digoxin and Outcomes in Patients with Heart Failure and Preserved Ejection Fraction (HFpEF) Patients: A Systematic Review and Meta- Analysis	3
BRD4 Protein as a Target for Lung Cancer and Hematological Cancer Therapy: A Review	3
Advances in Protein-Ligand Binding Affinity Prediction via Deep Learning: A Comprehensive Study of Datasets, Data Preprocessing Techniques, and Model Architectures	3
Structural Modifications in Chitosan Polymer Carries Synergistic Transfection in Drug Targeting	3
A Comprehensive Review on Nanomedicine: Promising Approach for Treatment of Brain Tumor through Intranasal Administration	3
Role of Vitamins in Therapeutic and Targeting Approaches for Prostate Cancer: An Overview	3
Toxic, Genotoxic and Teratogenic Effects of Ibuprofen and its Derivatives	3
The Marriage between Nanotechnology and Stem Cells Secretome for COPD	2
Meet the Regional Editor	2
Combinational Approaches Targeting Various Aspects Involved in Intestinal Barrier Dysfunction-Induced Anxiety	2
Canonical Wnt/Beta-Catenin Signaling Network as Emerging Signaling Cascade for Therapeutic Intervention in Chronic Renal Disease	2
A Review on Recent Development of Novel Heterocycles as Acetylcholinesterase Inhibitor for the Treatment of Alzheimer’s Disease	2
Tissue Factor and COVID-19: An Update	2
Deciphering the Function of New Therapeutic Targets and Prospective Biomarkers in the Management of Psoriasis	2
Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: An Overview	2
Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace	2
The Role of Host-Cellular Responses in COVID-19 Endothelial Dysfunction	2
Recent Progress on Apoptotic Activity of Triazoles	2
Intra-articular Treatment with Triamcinolone Hexacetonide Associated with Gold Nanoparticles Reduces Cartilage Degeneration in an Animal Model of Osteoarthritis	2
Radical Scavenging, Anti-Inflammatory, and Hepatoprotective Activities of Pentacyclic Triterpene isolated from Rosa webbiana	2
Insight γ-Secretase: Structure, Function, and Role in Alzheimer’s Disease	2
A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer’s Disease	2
The Gut Microbiota and Traditional Chinese Medicine: A New Clinical Frontier on Cancer	2
Recent Advances in the Prevention and Management of Monkeypox Viral Infection in Humans	2
Self-Assembled Micelles of Amphiphilic PEGylated Drugs for Cancer Treatment	2
Role of Poly(ADP-ribose) Polymerase (PARP1) in Viral Infection and its Implication in SARS-CoV-2 Pathogenesis	2
SGK-1 Signalling Pathway is a Key Factor in Cell Survival in Ischemic Injury	2
Estimating the Survival Rate in Glioblastoma Multiforme Patients who Received a Peptide Vaccine: A Systematic Review and Meta-analysis	2
Oral Semaglutide in the Management of Type 2 DM: Clinical Status and Comparative Analysis	2
Compounds Multi-targets against Neglected Diseases	2
Fibrinolysis in COVID-19: Impact on Clot Lysis and Modulation of Inflammation	2
Review of the Biological Activity of Maslinic Acid	2
Inhibition of Virulence Factors and Biofilm Formation ofAcinetobacter Baumanniiby Naturally-derived and Synthetic Drugs	2
Targeting SERCA2 in Anti-Tumor Drug Discovery	2
MT1JP: A Pivotal Tumor-Suppressing LncRNA and its Role in Cancer Progression and Therapeutic Potential	2
Targeting Protein Phosphatases for the Treatment of Chronic Liver Disease	2
Investigational Agents Targeting SGLT1 and SGLT2 in the Treatment of Type 2 Diabetes Mellitus	2
Viaminate Inhibits Propionibacterium Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade	2
Biomarkers and Treatment Strategies for Breast Cancer Recurrence	2
Tebentafusp as a Promising Drug for the Treatment of Uveal Melanoma	2
The Potential of Mur Enzymes as Targets for Antimicrobial Drug Discovery	2
Corrigendum to: Can Medical Therapy Fix Sexual Dysfunction after Major Pelvic and Prostate Surgery and does it Work for Kidney Stones? Chemotherapy before Cystectomy, New Schemes for which Patients?	2
Omega-3 Fatty Acid Treatment Combined with Chemotherapy to Prevent Toxicity, Drug Resistance, and Metastasis in Cancer	2
Recent Advances in Nanotechnology-Based Drug Delivery Approaches for Alzheimer disease	2
Inflammatory Bowel Disease in Migrant Populations: Should we Look Even Further Back?	2
In Vivo Models of Steroid-Induced Intraocular Hypertension	2
An Insight into Hepatitis C Virus: In Search of Promising Drug Targets	2
Mitochondrial Dysfunction in Huntington’s Disease: Pathogenesis and Therapeutic Opportunities	2
DRP1 Association in Inflammation and Metastasis: A Review	2
Novel Targets and Drug Delivery System in the Treatment of Postoperative Pain: Recent Studies and Clinical Advancement	2
HPV-mediated Cervical Cancer: A Systematic Review on Immunological Basis, Molecular Biology, and Immune Evasion Mechanisms	2
Trends on Nanomedicines as Novel therapeutics Approach in Targeting Nociceptors for Relieving Pain	2
Acknowledgements to Reviewers	2
Elucidation of Abnormal Extracellular Regulated Kinase (ERK) Signaling and Associations with Syndromic and Non-syndromic Autism	2
Targeting AMPK Signaling in the Liver: Implications for Obesity and Type 2 Diabetes Mellitus	2
Microtubules and Cell Division: Potential Pharmacological Targets in Cancer Therapy	2
The Extracapsular Lymph Node Extension Predicts Outcomes in Colorectal Cancer: A Short Review	2