OOIR: Observatory of International Research

Papers

(The TQCC of Current Protein & Peptide Science is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Withdrawal Notice: Overview of Enzyme Engineering Towards the Production of Hyaluronic Acid with Tailored Molecular Weight	37
Targeted Delivery of Diphtheria Toxin into VEGFR1/VEGFR2 Overexpressing Cells Induces Anti-angiogenesis Activity	33
Natural and Synthetic Peptides to Control Drug-resistant Pathogens	30
Revolutionizing Infertility Management through Novel Peptide-based Targets	29
Outdoor Allergens of Regional Importance in Asia	23
Markers of Oxidative Stress and Tyrosinase Activity in Melasma Patients: A Biochemical Investigation	23
Plant Lectins: A Review on their Biotechnological Potential Toward Human Pathogens	22
Current Trends and Challenges in Targeting Tumor Mitochondrial Glycolysis and Oxidative Phosphorylation Pathways for Cancer Therapy	22
Review of post-translational modification of human serum albumin	22
A Review on Anaplastic Lymphoma Kinase (ALK) Rearrangements and Mutations: Implications for Gastric Carcinogenesis and Target Therapy	19
Aspartate β-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis via Upregulating SHH Signaling Pathway	17
Apolipoprotein-mimetic Peptides: Current and Future Prospectives	17
An Update on Dipeptidyl Peptidase-IV Inhibiting Peptides	16
Structure and Function of the Important Internalins of Listeria monocytogenes	15
From Bugs to Benefits: Edible Insects as Exceptional Protein Sources	15
Identification of Tyrosinase Inhibitory Peptides from Sea Cucumber (Apostichopus japonicus) Collagen by in silico Methods and Study of their Molecular Mechanism	15
A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes, Renal Dysfunction, and Ischemic Stroke	14
Unveiling the Role of DPYS: A New Prognostic Biomarker in Sarcoma	14
ACE2 Receptor: A Potential Pharmacological Target in COVID-19	14
Histone Methylation Regulation as a Potential Target for Non-alcoholic Fatty Liver Disease	14
Current Update on New Delhi Metallo-β-lactamase (NDM) Variants: New Challenges in the Journey of Evolution	14
Oak Pollen Allergy in Korea	12
Overexpression of Efflux Pumps AcrAB and OqxAB Contributes to Ciprofloxacin Resistance in Clinical Isolates of K. pneumoniae	12
A Review on the Pathophysiology of Alzheimer’s Disease	11
Nanoparticles: A Promising Tool to Promote Reactive Oxygen Species in Cancer Therapy	11

Versatility of Collagen as a Natural Biopolymer for Biomedical, Food, and Cosmetic Applications	11
In Silico and In vitro Analysis of Phenolic Acids for Identification of Potential DHFR Inhibitors as Antimicrobial and Anticancer Agents	10
Herbs and their Active Constituents for Gastric Cancer and Related Problems - Preclinical and Clinical Studies	10
Small-Molecule Inhibitors Targeting eIF4A in Leukemia	10
Structural Analysis of the Interaction between Bcl-xL and the Noncanonical BH3 Domain of Non-Bcl-2 Family Proteins	10
Deciphering the Role of S-adenosyl Homocysteine Nucleosidase in Quorum Sensing Mediated Biofilm Formation	10
Recovery of Proteases and Protease Inhibitors from Ganoderma spp. Cultivated in Amazonian Lignocellulose Wastes	10
Diverse Role of SNARE Protein GS28 in Vesicle Trafficking and Diseases	10
Glycation of Immunoglobulin-G from Pentose Sugar: A Cause for Structural Perturbations	9
Chloride Intracellular Channel 1 Enhances Glioblastoma Cell Migration and Epithelial-Mesenchymal Transition by Activating the ERK1/2 Signaling Pathway	9
How Useful are Antimicrobial Peptide Properties for Predicting Activity, Selectivity, and Potency?	9
Leishmaniasis: Omics Approaches to Understand its Biology from Molecule to Cell Level	8
Metallopeptidases as Key Virulence Attributes of Clinically Relevant Protozoa: New Discoveries, Perspectives, and Frontiers of Knowledge	8
Kenaf Seed Cysteine Protease (KSCP) Inhibits the Intrinsic Pathway of the Blood Coagulation Cascade and Platelet Aggregation	8
Structure-Function Relationship of Homogentisate 1,2-dioxygenase: Understanding the Genotype-Phenotype Correlations in the Rare Genetic Disease Alkaptonuria	8
Soybean β-Conglycinin: Structure Characteristic, Allergenicity, Plasma Lipid-Controlling, Prevention of Obesity and Non-alcoholic Fatty Liver Disease	8
Anti-Platelet Peptides Targeting αIIbβ3 Outside-In Signaling Pathway	8
Post Translational Modification and Its Pathologic Association in Rheumatoid Arthritis: A Brief Perspective	8
Bacterial Pathogens: Potential Source For Antimicrobial Peptides	8
Identification of Protein Drug Targets of Biofilm Formation and Quorum Sensing in Multidrug Resistant Enterococcus faecalis	8
Bcl-2 Family Proteins in Therapeutic Arena for Cancers	8
Manipulating Metabolic Alterations and their Consequences to Unleash the Potential of Antitumor Immunotherapy	8
Trehalose and its Diverse Biological Potential	8
Understanding the Role of NRF2 Signalling in Cancer	8
Neurokinin B Administration Induces Dose Dependent Proliferation of Seminal Vesicles in Adult Rats	7
Birch Pollen Allergens	7
Glucagon-Like Peptide-2 in the Control of Gastrointestinal Motility: Physiological Implications	7
Hypoxia A Typical Target in Human Lung Cancer Therapy	7
Research Progress on hCNT3 Structure/Function and Nucleoside Anticancer Drugs	7
ARL15 and its Multiple Disease Association: Emerging Functions and Potential Therapeutic Application	7
Protein Folding, Aggregation, and Liquid-Liquid Phase Separation	6
Profilin and Its Isoforms: Unravelling the Functional Diversity Across Life Forms	6
Global Trends in Hepatocellular Carcinoma and TGF-β Research: A Bibliometric and Visualization Analysis from 2000 to 2024	6
Prognostic Role of Unfolded Protein Response-Related Genes in Hepatocellular Carcinoma	6
The Fulcrum of Demyelination in Multiple Sclerosis	6
A Comprehensive Comparative Review of Protein Sequence-Based Computational Prediction Models of Lysine Succinylation Sites	6
Research Progress on Extracellular Matrix Involved in the Development of Preeclampsia	6
Recent Advances in Molecular Imprinting for Proteins on Magnetic Microspheres	6
Epigenetic Regulator ASXL2: Structure, Function and its Predictive Value in Diseases	6
Programmed Cell Death in Plants: Insights into Developmental and Stress-Induced Cell Death	6
Protein Engineering in Cyanobacterial Biotechnology: Tools and Recent Updates	6
Artificial Intelligence in Proteins and Peptides: A Comprehensive Overview from Hybrid Modeling to Deep Learning	6
Exploring the Potential Role of Phytopharmaceuticals in Alleviating Toxicities of Chemotherapeutic Agents	6
Influences of Ipomoea batatas Anti-Cancer Peptide on Tomato Defense Genes	6
Biological Significance of EphB4 Expression in Cancer	6
Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis	6
Down-Regulated JDP2 Attenuated Trophoblast Invasion and Migration in Preeclampsia by Inhibiting Epithelial-Mesenchymal Transition through the Wnt/β-Catenin Pathway	5
Evaluation of Serum Humanin and MOTS-c Peptide Levels in Patients with COVID-19 and Healthy Subjects	5
Measurement of High Protein Concentrations by Optical Rotation: A Case Study for Monitoring of Monoclonal Antibody Drug Downstream Processes	5
Evolution of Immunotherapy Against Pollen Allergy	5

Plant bZIP Proteins: Potential use in Agriculture - A Review	5
Withdrawal Notice: Novel Sequence Features of Leucine-rich Repeats in Proteins from Nucleocytoplasmic Large DNA Viruses	5
In-vitro, In-silico Investigations Reveals Potential Cytotoxic Activity of Fermentation Metabolites from Actinomycetes Isolated from Lonar Soda Lake Against HeLa Cancer Cell Lines	5
Knockdown of Ubiquitin-Conjugating Enzyme E2 T Abolishes the Progression of Head and Neck Squamous Cell Carcinoma by Inhibiting NF-Κb Signaling and inducing Ferroptosis	5
Novel bone Morphogenetic Protein (BMP)-2/4 Consensus Peptide (BCP) for the Osteogenic Differentiation of C2C12 Cells	5
MicroRNA, a Promising Biomarker for Breast and Ovarian Cancer: A Review	5
Comprehensive Analysis of Glycosyltransferase-Related Genes Reveals their Prognostic and Therapeutic Implications in Stomach Adenocarcinoma	5
PPA1, TRIM68 and FBXO46: Potential Therapeutic Targets for Triple Negative Breast Cancer	5
Interaction of Nanomaterials with Protein-Peptide	5
Short Amphiphiles or Micelle Peptides May Help to Fight Against COVID-19	5
Cell Surface Markers and their Targeted Drugs in Breast Cancer	5
Exploring the Molecular Aspects of Glycosylation in MOG Antibody Disease (MOGAD)	5