OOIR: Observatory of International Research

Papers

(The TQCC of Current Protein & Peptide Science is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Withdrawal Notice: Overview of Enzyme Engineering Towards the Production of Hyaluronic Acid with Tailored Molecular Weight	79
Targeted Delivery of Diphtheria Toxin into VEGFR1/VEGFR2 Overexpressing Cells Induces Anti-angiogenesis Activity	30
Plant Lectins: A Review on their Biotechnological Potential Toward Human Pathogens	27
Apolipoprotein-mimetic Peptides: Current and Future Prospectives	26
Natural and Synthetic Peptides to Control Drug-resistant Pathogens	26
Revolutionizing Infertility Management through Novel Peptide-based Targets	26
Review of post-translational modification of human serum albumin	22
Outdoor Allergens of Regional Importance in Asia	21
Markers of Oxidative Stress and Tyrosinase Activity in Melasma Patients: A Biochemical Investigation	20
Current Trends and Challenges in Targeting Tumor Mitochondrial Glycolysis and Oxidative Phosphorylation Pathways for Cancer Therapy	20
An Update on Dipeptidyl Peptidase-IV Inhibiting Peptides	19
Overexpression of Efflux Pumps AcrAB and OqxAB Contributes to Ciprofloxacin Resistance in Clinical Isolates of K. pneumoniae	17
Aspartate β-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis via Upregulating SHH Signaling Pathway	17
A Review on Anaplastic Lymphoma Kinase (ALK) Rearrangements and Mutations: Implications for Gastric Carcinogenesis and Target Therapy	17
Unveiling the Role of DPYS: A New Prognostic Biomarker in Sarcoma	16
Identification of Tyrosinase Inhibitory Peptides from Sea Cucumber (Apostichopus japonicus) Collagen by in silico Methods and Study of their Molecular Mechanism	15
Current Update on New Delhi Metallo-β-lactamase (NDM) Variants: New Challenges in the Journey of Evolution	15
Structure and Function of the Important Internalins of Listeria monocytogenes	15
ACE2 Receptor: A Potential Pharmacological Target in COVID-19	14
A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes, Renal Dysfunction, and Ischemic Stroke	14
Nanoparticles: A Promising Tool to Promote Reactive Oxygen Species in Cancer Therapy	13
Histone Methylation Regulation as a Potential Target for Non-alcoholic Fatty Liver Disease	13
Oak Pollen Allergy in Korea	11
In Silico and In vitro Analysis of Phenolic Acids for Identification of Potential DHFR Inhibitors as Antimicrobial and Anticancer Agents	11
Deciphering the Role of S-adenosyl Homocysteine Nucleosidase in Quorum Sensing Mediated Biofilm Formation	11

Understanding The Role of Inflammasome in Angina Pectoris	10
Glycation of Immunoglobulin-G from Pentose Sugar: A Cause for Structural Perturbations	10
Small-Molecule Inhibitors Targeting eIF4A in Leukemia	10
Diverse Role of SNARE Protein GS28 in Vesicle Trafficking and Diseases	9
Structural Analysis of the Interaction between Bcl-xL and the Noncanonical BH3 Domain of Non-Bcl-2 Family Proteins	9
Metallopeptidases as Key Virulence Attributes of Clinically Relevant Protozoa: New Discoveries, Perspectives, and Frontiers of Knowledge	9
How Useful are Antimicrobial Peptide Properties for Predicting Activity, Selectivity, and Potency?	8
Chloride Intracellular Channel 1 Enhances Glioblastoma Cell Migration and Epithelial-Mesenchymal Transition by Activating the ERK1/2 Signaling Pathway	8
Recovery of Proteases and Protease Inhibitors from Ganoderma spp. Cultivated in Amazonian Lignocellulose Wastes	8
Bcl-2 Family Proteins in Therapeutic Arena for Cancers	8
Anti-Platelet Peptides Targeting αIIbβ3 Outside-In Signaling Pathway	8
Post Translational Modification and Its Pathologic Association in Rheumatoid Arthritis: A Brief Perspective	8
Kenaf Seed Cysteine Protease (KSCP) Inhibits the Intrinsic Pathway of the Blood Coagulation Cascade and Platelet Aggregation	7
Structure-Function Relationship of Homogentisate 1,2-dioxygenase: Understanding the Genotype-Phenotype Correlations in the Rare Genetic Disease Alkaptonuria	7
ARL15 and its Multiple Disease Association: Emerging Functions and Potential Therapeutic Application	7
Soybean β-Conglycinin: Structure Characteristic, Allergenicity, Plasma Lipid-Controlling, Prevention of Obesity and Non-alcoholic Fatty Liver Disease	7
Manipulating Metabolic Alterations and their Consequences to Unleash the Potential of Antitumor Immunotherapy	7
Are Hsp90 Inhibitors Good Candidates Against Covid-19?	7
Leishmaniasis: Omics Approaches to Understand its Biology from Molecule to Cell Level	7
Bacterial Pathogens: Potential Source For Antimicrobial Peptides	7
Trehalose and its Diverse Biological Potential	7
Glucagon-Like Peptide-2 in the Control of Gastrointestinal Motility: Physiological Implications	6
Programmed Cell Death in Plants: Insights into Developmental and Stress-Induced Cell Death	6
Identification of Protein Drug Targets of Biofilm Formation and Quorum Sensing in Multidrug Resistant Enterococcus faecalis	6
Research Progress on hCNT3 Structure/Function and Nucleoside Anticancer Drugs	6
Neurokinin B Administration Induces Dose Dependent Proliferation of Seminal Vesicles in Adult Rats	6
Birch Pollen Allergens	6
Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis	6
Hypoxia A Typical Target in Human Lung Cancer Therapy	6
Peroxiredoxin-6: A Guardian of Lung Pathophysiologies	6
Reconsidering and Reforming the Amyloid Cascade Hypothesis	5
Measurement of High Protein Concentrations by Optical Rotation: A Case Study for Monitoring of Monoclonal Antibody Drug Downstream Processes	5
The Fulcrum of Demyelination in Multiple Sclerosis	5
Exploring the Potential Role of Phytopharmaceuticals in Alleviating Toxicities of Chemotherapeutic Agents	5
Biological Significance of EphB4 Expression in Cancer	5
Evaluation of Serum Humanin and MOTS-c Peptide Levels in Patients with COVID-19 and Healthy Subjects	5
Recent Advances in Molecular Imprinting for Proteins on Magnetic Microspheres	5
Understanding the Role of NRF2 Signalling in Cancer	5
Comprehensive Review and Comparison of Anticancer Peptides Identification Models	5
Protein Engineering in Cyanobacterial Biotechnology: Tools and Recent Updates	5
Knockdown of Ubiquitin-Conjugating Enzyme E2 T Abolishes the Progression of Head and Neck Squamous Cell Carcinoma by Inhibiting NF-Κb Signaling and inducing Ferroptosis	5
Lactoferrin as a Potent Natural Supplement Exhibiting a Synergistic Effect with Drugs in Antimicrobial and Anticancer Therapies	5
A Comprehensive Comparative Review of Protein Sequence-Based Computational Prediction Models of Lysine Succinylation Sites	5
Research Progress on Extracellular Matrix Involved in the Development of Preeclampsia	5
Interaction of Nanomaterials with Protein-Peptide	4
Epigenetic Regulator ASXL2: Structure, Function and its Predictive Value in Diseases	4
In-vitro, In-silico Investigations Reveals Potential Cytotoxic Activity of Fermentation Metabolites from Actinomycetes Isolated from Lonar Soda Lake Against HeLa Cancer Cell Lines	4
Withdrawal Notice: Novel Sequence Features of Leucine-rich Repeats in Proteins from Nucleocytoplasmic Large DNA Viruses	4
Plant bZIP Proteins: Potential use in Agriculture - A Review	4
Cell Surface Markers and their Targeted Drugs in Breast Cancer	4

Novel bone Morphogenetic Protein (BMP)-2/4 Consensus Peptide (BCP) for the Osteogenic Differentiation of C2C12 Cells	4
PPA1, TRIM68 and FBXO46: Potential Therapeutic Targets for Triple Negative Breast Cancer	4
Prognostic Role of Unfolded Protein Response-Related Genes in Hepatocellular Carcinoma	4
Difference of MreBCD Complex Interactome in Salmonella Typhimurium ST19 and ST213 Genotypes on Pathogenesis and Stress Response Pathways	4
Preface	4
Bioconjugation Techniques for Enhancing Stability and Targeting Efficiency of Protein and Peptide Therapeutics	4
Spectroscopic Analysis of the Effect of Ibuprofen Degradation Products on the Interaction between Ibuprofen and Human Serum Albumin	4
Exploring the Molecular Aspects of Glycosylation in MOG Antibody Disease (MOGAD)	4
Influences of Ipomoea batatas Anti-Cancer Peptide on Tomato Defense Genes	4
Short Amphiphiles or Micelle Peptides May Help to Fight Against COVID-19	4
Melatonin Against Environmental Plant Stressors: A Review	4
Preface	4
MicroRNA, a Promising Biomarker for Breast and Ovarian Cancer: A Review	4
Evolution of Immunotherapy Against Pollen Allergy	4
Down-Regulated JDP2 Attenuated Trophoblast Invasion and Migration in Preeclampsia by Inhibiting Epithelial-Mesenchymal Transition through the Wnt/β-Catenin Pathway	4