OOIR: Observatory of International Research

Papers

(The TQCC of Current Protein & Peptide Science is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Targeted Delivery of Diphtheria Toxin into VEGFR1/VEGFR2 Overexpressing Cells Induces Anti-angiogenesis Activity	39
Natural and Synthetic Peptides to Control Drug-resistant Pathogens	35
Revolutionizing Infertility Management through Novel Peptide-based Targets	30
Markers of Oxidative Stress and Tyrosinase Activity in Melasma Patients: A Biochemical Investigation	23
Outdoor Allergens of Regional Importance in Asia	23
Plant Lectins: A Review on their Biotechnological Potential Toward Human Pathogens	22
Current Trends and Challenges in Targeting Tumor Mitochondrial Glycolysis and Oxidative Phosphorylation Pathways for Cancer Therapy	22
Aspartate β-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis via Upregulating SHH Signaling Pathway	19
Review of post-translational modification of human serum albumin	19
A Review on Anaplastic Lymphoma Kinase (ALK) Rearrangements and Mutations: Implications for Gastric Carcinogenesis and Target Therapy	19
Apolipoprotein-mimetic Peptides: Current and Future Prospectives	15
Identification of Tyrosinase Inhibitory Peptides from Sea Cucumber (Apostichopus japonicus) Collagen by in silico Methods and Study of their Molecular Mechanism	15
An Update on Dipeptidyl Peptidase-IV Inhibiting Peptides	15
Histone Methylation Regulation as a Potential Target for Non-alcoholic Fatty Liver Disease	14
Current Update on New Delhi Metallo-β-lactamase (NDM) Variants: New Challenges in the Journey of Evolution	14
From Bugs to Benefits: Edible Insects as Exceptional Protein Sources	14
ACE2 Receptor: A Potential Pharmacological Target in COVID-19	14
A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes, Renal Dysfunction, and Ischemic Stroke	13
Unveiling the Role of DPYS: A New Prognostic Biomarker in Sarcoma	12
Oak Pollen Allergy in Korea	12
Overexpression of Efflux Pumps AcrAB and OqxAB Contributes to Ciprofloxacin Resistance in Clinical Isolates of K. pneumoniae	12
Versatility of Collagen as a Natural Biopolymer for Biomedical, Food, and Cosmetic Applications	11
A Review on the Pathophysiology of Alzheimer’s Disease	11
Deciphering the Role of S-adenosyl Homocysteine Nucleosidase in Quorum Sensing Mediated Biofilm Formation	11
Diverse Role of SNARE Protein GS28 in Vesicle Trafficking and Diseases	10

How Useful are Antimicrobial Peptide Properties for Predicting Activity, Selectivity, and Potency?	10
In Silico and In vitro Analysis of Phenolic Acids for Identification of Potential DHFR Inhibitors as Antimicrobial and Anticancer Agents	10
Herbs and their Active Constituents for Gastric Cancer and Related Problems - Preclinical and Clinical Studies	10
Chloride Intracellular Channel 1 Enhances Glioblastoma Cell Migration and Epithelial-Mesenchymal Transition by Activating the ERK1/2 Signaling Pathway	10
Recovery of Proteases and Protease Inhibitors from Ganoderma spp. Cultivated in Amazonian Lignocellulose Wastes	10
Glycation of Immunoglobulin-G from Pentose Sugar: A Cause for Structural Perturbations	10
Bcl-2 Family Proteins in Therapeutic Arena for Cancers	9
Metallopeptidases as Key Virulence Attributes of Clinically Relevant Protozoa: New Discoveries, Perspectives, and Frontiers of Knowledge	9
Structural Analysis of the Interaction between Bcl-xL and the Noncanonical BH3 Domain of Non-Bcl-2 Family Proteins	9
Leishmaniasis: Omics Approaches to Understand its Biology from Molecule to Cell Level	9
Anti-Platelet Peptides Targeting αIIbβ3 Outside-In Signaling Pathway	9
Bacterial Pathogens: Potential Source For Antimicrobial Peptides	8
Understanding the Role of NRF2 Signalling in Cancer	8
Identification of Protein Drug Targets of Biofilm Formation and Quorum Sensing in Multidrug Resistant Enterococcus faecalis	8
Trehalose and its Diverse Biological Potential	8
Structure-Function Relationship of Homogentisate 1,2-dioxygenase: Understanding the Genotype-Phenotype Correlations in the Rare Genetic Disease Alkaptonuria	8
Neurokinin B Administration Induces Dose Dependent Proliferation of Seminal Vesicles in Adult Rats	8
Kenaf Seed Cysteine Protease (KSCP) Inhibits the Intrinsic Pathway of the Blood Coagulation Cascade and Platelet Aggregation	8
Manipulating Metabolic Alterations and their Consequences to Unleash the Potential of Antitumor Immunotherapy	8
Glucagon-Like Peptide-2 in the Control of Gastrointestinal Motility: Physiological Implications	8
Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis	7
The Fulcrum of Demyelination in Multiple Sclerosis	7
Birch Pollen Allergens	7
ARL15 and its Multiple Disease Association: Emerging Functions and Potential Therapeutic Application	7
Protein Engineering in Cyanobacterial Biotechnology: Tools and Recent Updates	7
Research Progress on hCNT3 Structure/Function and Nucleoside Anticancer Drugs	7
Hypoxia A Typical Target in Human Lung Cancer Therapy	7
Protein Folding, Aggregation, and Liquid-Liquid Phase Separation	7
A Comprehensive Comparative Review of Protein Sequence-Based Computational Prediction Models of Lysine Succinylation Sites	6
Exploring the Potential Role of Phytopharmaceuticals in Alleviating Toxicities of Chemotherapeutic Agents	6
Recent Advances in Molecular Imprinting for Proteins on Magnetic Microspheres	6
Epigenetic Regulator ASXL2: Structure, Function and its Predictive Value in Diseases	6
Knockdown of Ubiquitin-Conjugating Enzyme E2 T Abolishes the Progression of Head and Neck Squamous Cell Carcinoma by Inhibiting NF-Κb Signaling and inducing Ferroptosis	6
Artificial Intelligence in Proteins and Peptides: A Comprehensive Overview from Hybrid Modeling to Deep Learning	6
Biological Significance of EphB4 Expression in Cancer	6
Research Progress on Extracellular Matrix Involved in the Development of Preeclampsia	6
In-vitro, In-silico Investigations Reveals Potential Cytotoxic Activity of Fermentation Metabolites from Actinomycetes Isolated from Lonar Soda Lake Against HeLa Cancer Cell Lines	6
Influences of Ipomoea batatas Anti-Cancer Peptide on Tomato Defense Genes	6
Profilin and Its Isoforms: Unravelling the Functional Diversity Across Life Forms	6
Global Trends in Hepatocellular Carcinoma and TGF-β Research: A Bibliometric and Visualization Analysis from 2000 to 2024	6
Prognostic Role of Unfolded Protein Response-Related Genes in Hepatocellular Carcinoma	6
Interaction of Nanomaterials with Protein-Peptide	6
Short Amphiphiles or Micelle Peptides May Help to Fight Against COVID-19	5
Evaluation of Serum Humanin and MOTS-c Peptide Levels in Patients with COVID-19 and Healthy Subjects	5
Plant bZIP Proteins: Potential use in Agriculture - A Review	5
Preface	5
Molecular Characterization, Expression and In Situ Hybridization Analysis of a Pedal Peptide/Orcokinin-type Neuropeptide in Cuttlefish Sepiella japonica	5
Exploring the Molecular Aspects of Glycosylation in MOG Antibody Disease (MOGAD)	5
Down-Regulated JDP2 Attenuated Trophoblast Invasion and Migration in Preeclampsia by Inhibiting Epithelial-Mesenchymal Transition through the Wnt/β-Catenin Pathway	5
Comprehensive Analysis of Glycosyltransferase-Related Genes Reveals their Prognostic and Therapeutic Implications in Stomach Adenocarcinoma	5

Bioconjugation Techniques for Enhancing Stability and Targeting Efficiency of Protein and Peptide Therapeutics	5
Spectroscopic Analysis of the Effect of Ibuprofen Degradation Products on the Interaction between Ibuprofen and Human Serum Albumin	5
Evolution of Immunotherapy Against Pollen Allergy	5
PPA1, TRIM68 and FBXO46: Potential Therapeutic Targets for Triple Negative Breast Cancer	5
Novel bone Morphogenetic Protein (BMP)-2/4 Consensus Peptide (BCP) for the Osteogenic Differentiation of C2C12 Cells	5
Preface	5
Cell Surface Markers and their Targeted Drugs in Breast Cancer	5
Irisin, a mediator of muscle crosstalk with other organs: from metabolism regulation to protective and regenerative effects	5