Current Protein & Peptide Science

Article	Citations
Targeted Delivery of Diphtheria Toxin into VEGFR1/VEGFR2 Overexpressing Cells Induces Anti-angiogenesis Activity	45
Natural and Synthetic Peptides to Control Drug-resistant Pathogens	43
Revolutionizing Infertility Management through Novel Peptide-based Targets	38
Outdoor Allergens of Regional Importance in Asia	28
A Review on Anaplastic Lymphoma Kinase (ALK) Rearrangements and Mutations: Implications for Gastric Carcinogenesis and Target Therapy	25
Lipidation & Stapled Peptides: Enhancing Stability and Pharmacokinetics	24
Plant Lectins: A Review on their Biotechnological Potential Toward Human Pathogens	24
Aspartate β-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis via Upregulating SHH Signaling Pathway	22
Markers of Oxidative Stress and Tyrosinase Activity in Melasma Patients: A Biochemical Investigation	21
An Update on Dipeptidyl Peptidase-IV Inhibiting Peptides	21
2026: The Year of Innovation, Sustainability, and Education in Protein and Peptide Science	19
Current Trends and Challenges in Targeting Tumor Mitochondrial Glycolysis and Oxidative Phosphorylation Pathways for Cancer Therapy	18
Apolipoprotein-mimetic Peptides: Current and Future Prospectives	18
Histone Methylation Regulation as a Potential Target for Non-alcoholic Fatty Liver Disease	17
Aminated Polyrotaxanes as Next-Generation Excipients: Dual Roles in Stabilization and Drug Delivery of Injectable Biologics	17
Unveiling the Role of DPYS: A New Prognostic Biomarker in Sarcoma	15
From Bugs to Benefits: Edible Insects as Exceptional Protein Sources	15
Current Update on New Delhi Metallo-β-lactamase (NDM) Variants: New Challenges in the Journey of Evolution	14
Identification of Tyrosinase Inhibitory Peptides from Sea Cucumber (Apostichopus japonicus) Collagen by in silico Methods and Study of their Molecular Mechanism	13
ACE2 Receptor: A Potential Pharmacological Target in COVID-19	13
In Silico and In vitro Analysis of Phenolic Acids for Identification of Potential DHFR Inhibitors as Antimicrobial and Anticancer Agents	12
Oak Pollen Allergy in Korea	12
A Review on the Pathophysiology of Alzheimer’s Disease	12
A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes, Renal Dysfunction, and Ischemic Stroke	12
The Relationship between S100A9 Protein Levels and Diabetic Retinopathy among Type 2 Diabetes Patients: A Meta-Analysis	11

Versatility of Collagen as a Natural Biopolymer for Biomedical, Food, and Cosmetic Applications	11
The Role of Antimicrobial Peptide (AMP) Delivery Systems in Combating Antimicrobial Resistance: Current Trends and Novel Approaches	11
Glycation of Immunoglobulin-G from Pentose Sugar: A Cause for Structural Perturbations	10
Recovery of Proteases and Protease Inhibitors from Ganoderma spp. Cultivated in Amazonian Lignocellulose Wastes	10
Chloride Intracellular Channel 1 Enhances Glioblastoma Cell Migration and Epithelial-Mesenchymal Transition by Activating the ERK1/2 Signaling Pathway	10
Diverse Role of SNARE Protein GS28 in Vesicle Trafficking and Diseases	10
Herbs and their Active Constituents for Gastric Cancer and Related Problems - Preclinical and Clinical Studies	10
Bcl-2 Family Proteins in Therapeutic Arena for Cancers	9
Metallopeptidases as Key Virulence Attributes of Clinically Relevant Protozoa: New Discoveries, Perspectives, and Frontiers of Knowledge	9
Structural Analysis of the Interaction between Bcl-xL and the Noncanonical BH3 Domain of Non-Bcl-2 Family Proteins	9
How Useful are Antimicrobial Peptide Properties for Predicting Activity, Selectivity, and Potency?	9
Anti-Platelet Peptides Targeting αIIbβ3 Outside-In Signaling Pathway	9
Kenaf Seed Cysteine Protease (KSCP) Inhibits the Intrinsic Pathway of the Blood Coagulation Cascade and Platelet Aggregation	8
Leishmaniasis: Omics Approaches to Understand its Biology from Molecule to Cell Level	8
Manipulating Metabolic Alterations and their Consequences to Unleash the Potential of Antitumor Immunotherapy	8
Modulation of the Unfolded Protein Response by Viruses: Mechanistic Insights and Implications for viral Pathogenesis	8
Phα1β, a Peptide Derived from the Spider Phoneutria nigriventer, is a Potential New Antioxidant and Inflammation Modulator	8
Bacterial Pathogens: Potential Source For Antimicrobial Peptides	7
Trehalose and its Diverse Biological Potential	7
Neurokinin B Administration Induces Dose Dependent Proliferation of Seminal Vesicles in Adult Rats	7
The Fulcrum of Demyelination in Multiple Sclerosis	7
Birch Pollen Allergens	7
Research Progress on the Intervention of Traditional Chinese Medicine Monomers on Signaling Pathways Related to Sarcopenia and Osteoporosis	7
Understanding the Role of NRF2 Signalling in Cancer	7
Research Progress on hCNT3 Structure/Function and Nucleoside Anticancer Drugs	7
Hypoxia A Typical Target in Human Lung Cancer Therapy	7
Structure-Function Relationship of Homogentisate 1,2-dioxygenase: Understanding the Genotype-Phenotype Correlations in the Rare Genetic Disease Alkaptonuria	7
Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis	7
ARL15 and its Multiple Disease Association: Emerging Functions and Potential Therapeutic Application	7
Protein Engineering in Cyanobacterial Biotechnology: Tools and Recent Updates	7
Knockdown of Ubiquitin-Conjugating Enzyme E2 T Abolishes the Progression of Head and Neck Squamous Cell Carcinoma by Inhibiting NF-Κb Signaling and inducing Ferroptosis	6
Interaction of Nanomaterials with Protein-Peptide	6
Profilin and Its Isoforms: Unravelling the Functional Diversity Across Life Forms	6
A Comprehensive Comparative Review of Protein Sequence-Based Computational Prediction Models of Lysine Succinylation Sites	6
Influences of Ipomoea batatas Anti-Cancer Peptide on Tomato Defense Genes	6
Epigenetic Regulator ASXL2: Structure, Function and its Predictive Value in Diseases	6
Prognostic Role of Unfolded Protein Response-Related Genes in Hepatocellular Carcinoma	6
Protein Folding, Aggregation, and Liquid-Liquid Phase Separation	6
Global Trends in Hepatocellular Carcinoma and TGF-β Researc h: A Bibliometric and Visualization Analysis from 2000 to 2024	6
Exploring the Potential Role of Phytopharmaceuticals in Alleviating Toxicities of Chemotherapeutic Agents	6
PPA1, TRIM68 and FBXO46: Potential Therapeutic Targets for Triple Negative Breast Cancer	6
Evaluation of Serum Humanin and MOTS-c Peptide Levels in Patients with COVID-19 and Healthy Subjects	6
In-vitro, In-silico Investigations Reveals Potential Cytotoxic Activity of Fermentation Metabolites from Actinomycetes Isolated from Lonar Soda Lake Against HeLa Cancer Cell Lines	6
Artificial Intelligence in Proteins and Peptides: A Comprehensive Overview from Hybrid Modeling to Deep Learning	6
Research Progress on Extracellular Matrix Involved in the Development of Preeclampsia	6
Biological Significance of EphB4 Expression in Cancer	6
Preface	5
Down-Regulated JDP2 Attenuated Trophoblast Invasion and Migration in Preeclampsia by Inhibiting Epithelial-Mesenchymal Transition through the Wnt/β-Catenin Pathway	5
Multi-omics Analysis Reveals the Role of lncRNAs and Peptides in the Age-related Hearing Loss	5
Plant bZIP Proteins: Potential use in Agriculture - A Review	5

Exploring the Molecular Aspects of Glycosylation in MOG Antibody Disease (MOGAD)	5
Recent Advances in Molecular Imprinting for Proteins on Magnetic Microspheres	5
Evolution of Immunotherapy Against Pollen Allergy	5
PI3K/AKT Signaling as a Molecular Link Between Obesity and Female Infertility	5
To Fold, Unfold, or Aggregate: The Induced Coaggregation Mechanism of Amyloidogenic Antimicrobial Peptides for Combating Bacterial Communities	5
Spectroscopic Analysis of the Effect of Ibuprofen Degradation Products on the Interaction between Ibuprofen and Human Serum Albumin	5
Novel bone Morphogenetic Protein (BMP)-2/4 Consensus Peptide (BCP) for the Osteogenic Differentiation of C2C12 Cells	5
Comprehensive Analysis of Glycosyltransferase-Related Genes Reveals their Prognostic and Therapeutic Implications in Stomach Adenocarcinoma	5
Bioconjugation Techniques for Enhancing Stability and Targeting Efficiency of Protein and Peptide Therapeutics	5
Targeting Drug-Resistant Tuberculosis with Antimicrobial Peptides: Opportunities and Challenges	5
Caspase-3 Activators as Anticancer Agents	5
PAK1 Inhibition Suppresses the Proliferation, Migration and Invasion of Glioma Cells	4
The Role of Mitochondrial Ion Channels in the Evolution of Anticancer Drug Resistance	4
Solid-Phase Synthesized Imunofan Confers Clinically Relevant Protection using a Chimeric Protein Vaccine Candidate Against E. coli O157:H7 in BALB/c Mice	4
Carboxylic Group Functionalized Carbon Quantum Dots inhibit Hen Egg White Lysozyme Amyloidogenesis, leading to the Formation of Spherical Aggregates with Reduced Toxicity and ROS Generation	4
Genomic Analysis of the Caleosin Family in Theaceae Reveals Lineagespecific Evolutionary Patterns	4
Diabetic Wound: Pathophysiology, Complications and Treatment Strategies	4
Acknowledgements to Reviewers	4
Antimicrobial Peptides: Structure, Mechanisms, and Therapeutic Potential in Combating Infectious Diseases	4
Network Pharmacology and Experiments to Verify the Effect andPotential Mechanism of Baicalein on Osteoporosis	4
Bioactive Pentacyclic Triterpenes Trigger Multiple Signalling Pathways for Selective Apoptosis Leading to Anticancer Efficacy: Recent Updates and Future Perspectives	4
Soluble Factors Associated with Denervation-induced Skeletal Muscle Atrophy	4
Molecular Players at the Sorting Stations of Malaria Parasite ‘Plasmodium falciparum’	4
Unveiling the Advances in Protein Kinase: From Concept to Clinic	4
Molecular Characterization, Expression and In Situ Hybridization Analysis of a Pedal Peptide/Orcokinin-type Neuropeptide in Cuttlefish Sepiella japonica	4
Post-translational Modification that Shines in the Age of Viruses: ISGylation from a Structural Perspective	4
Enzymatic Targets in the Anticancer Drug Discovery	4
Potential of Angiotensin-(1-7) in COVID-19 Treatment	4
Unfolded Protein Response Signaling in Hepatic Stem Cell Activation in Liver Fibrosis	4
Therapeutic Horizons for Parkinson’s Disease: Current Relevance of PNA5 in Memory and Cognition	4
Comprehensive Overview of Treponema pallidum Outer Membrane Proteins	3
Intricacies of PKB/Akt Activity after Sciatic Nerve Damage: A Comprehensive Review	3
Phosphate Toxicity and Vascular Calcification in Chronic Kidney Disease: A Closer Look Utilizing Transmission Electron Microscopy	3
Vitamin D: A Repurposed Anti-inflammatory Drug at the Cardiovascular Level	3
Emerging Role of Non-collagenous Bone Proteins as Osteokines in Extraosseous Tissues	3
Plant SUT Sucrose Transporters: Structure, Evolution and Biological Functions	3
Messenger RNA Nanomedicine: Innovations and Future Directions	3
Recent Advancement in Novel Wound Healing Therapies by Using Antimicrobial Peptides Derived from Humans and Amphibians	3
Discovery of Sulfanilamide-diazo Derivatives Incorporating Benzoic Acid Moieties as Novel Inhibitors of Human Carbonic Anhydrase II Activity	3
Targeting Cdc42: Novel Approaches in Cardiovascular Disorders	3
A Perspective on the Impact of Advanced Glycation End Products in the Progression of Diabetic Nephropathy	3
Molecular Signaling and Biased Agonism of the CHEMR23 Receptor: Implications for Inflammation Resolution and Bone Remodeling	3
Insights into the Binding of Metadoxine with Bovine Serum Albumin: A Multi-Spectroscopic Investigation Combined with Molecular Docking	3
The Production, Properties, and Potential Food Applications of Proteins and Peptides from Marine Sources and their Structure-Function Relationship	3
MTA1: A Vital Modulator in Prostate Cancer	3
Advances in the Study of Noncoding RNAs in the Pathogenesis of Pregnancy-related Diseases	3
Aquatic BPI/LBPs: A Promising Antimicrobial Peptide Resource for Disease Control in Aquaculture	3
Preface	3
Lethal Yellow Mutation Causes Anxiety, Obsessive-compulsive Behavior and Affects the Brain Melanocortin System in Males and Females of Mice	3
Investigating the Mechanical Properties and Flexibility of N-BAR Domains in PICK1 by Molecular Dynamics Simulations	3
Demystifying Bacteriocins of Human Microbiota by Genome Guided Prospects: An Impetus to Rekindle the Antimicrobial Research	3
Dynamics of Ubiquitination in Differentiation and Dedifferentiation of Pancreatic β-cells: Putative Target for Diabetes	3
Enzymatic Characterization of Alkaline Protease from a Novel Microorganism Isolated from a Halophilic Environment	3
The Roles of IGF-1 and MGF on Nerve Regeneration under Hypoxia- Ischemia, Inflammation, Oxidative Stress, and Physical Trauma	3
An Overview of the Deubiquitinase USP53: A Promising Diagnostic Marker and Therapeutic Target	3
Human Paraoxonase 1: From Bloodstream Enzyme to Disease Fighter & Therapeutic Intervention	3
Tight Junctions in the Auditory System: Structure, Distribution and Function	3
Research Progress of Pectin Methylesterase and its Inhibitors	3
Advances in Migraine Treatment: A Comprehensive Clinical Review	3
MmpS5-MmpL5 Transporters Deliver M. tuberculosis Resistance to Bedaquiline (BDQ) and Delamanid (DLM)	3
Evaluation of Novel HLM Peptide Activity and Toxicity against Planktonic and Biofilm Bacteria: Comparison to Standard Antibiotics	2
Peroxisome Biogenesis and Proliferation During Stress	2
Determinants of Epitope Immunodominance Hierarchies in Protein Antigens at the Molecular, Structural, and Cellular Levels, Including MHC-Dependent Mechanisms	2
Circulating SFRP2 in Iranian Polycystic Ovarian Syndrome Patients with Infertility and Recurrent Pregnancy Loss and its Correlation with Insulin Resistance and Inflammation	2
Insight of Intestinal Fatty Acid Binding Protein as a Potential Biomarker in the Biology of Epithelial Damage of Gastrointestinal Membrane	2
Bile Acids as Signaling Molecules: Role of Ursodeoxycholic Acid in Cholestatic Liver Disease	2
The Role of Sirtuins in Diabetic Nephropathy: A Comprehensive Review	2
T-Box Transcription Factor 2 Enhances Chemoresistance of Endometrial Cancer by Mediating NRF2 Expression	2
RGD Peptide-Based Hydrogel Enhances the Osteogenic Differentiation of Periodontal Ligament Stem Cells via Wnt Signaling	2
Cysteine Peptidases of Calotropis procera (Apocynaceae): A Literature Review on their Biochemical Properties and Potential Applications	2
Pt(IV) Prodrug Photoactivation: A Promising Strategy for Cancer Therapy	2
Utilizing AfDesign for Developing a Small Molecule Inhibitor of PICK- 1-PDZ	2
Design of Multitarget Inhibitors as Tracheal Smooth Muscle Relaxants	2
A Valuable Target for Therapy: The Metalloproteinase ADAM10	2
Dominant Circulating Cell-free Mycobacterial Proteins in In-use Machining Fluid and their Antigenicity Potential	2
The Role of Various Autoantibodies and Alpha2-Macroglobulin in Patients with Hashimoto Disease: Does the Presence of Elevated Antibodies Correlate with Alpha 2-Macroglobulin Levels in Hashimoto Diseas	2
Inhibitors of Type II NADH Dehydrogenase Enzyme: A Review	2
TLR4 Targeting: A Promising Therapeutic Approach Across Multiple Human Diseases	2
Micelles-based Drug Delivery Systems: Implication, Challenges and Future Perspectives in Lung Cancer Therapy	2
Multi-Target Antioxidant Potential of Tricin Against Parkinson’s Disease- Linked Oxidative Stress	2

BH3 Mimetic Peptides: An Effective Strategy to Complement Anticancer Therapy	2
Protein Misfolding and Aggregation of Pathological IgG Light Chains in Oncohematological Dyscrasias: From Molecular Pathways to Clinical Implications	2
What Can Proteomics Tell us About COVID-19 Infections? Mass Spectrometry as a Tool to Find New Proteins as Biomarkers	1
Preface	1
SARS-CoV-2 Infection and C1-Esterase Inhibitor: Camouflage Pattern and New Perspective	1
CBX8 Promotes Epithelial-mesenchymal Transition, Migration, and Invasion of Lung Cancer through Wnt/β-catenin Signaling Pathway	1
Amyloids and Amyloid-like Protein Aggregates in Foods: Challenges and New Perspectives	1
Exploring Placental Protein-Target Protein Interactions: In Silico and In Vitro Approaches for Osteoarthritis Therapy	1
Emerging Hop Japanese Pollinosis in Asia	1
Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma	1
In Vitro Synergistic Inhibition and Eradication of Pathogenic Bacterial Biofilms by Bacillus subtilis-derived Anti-biofilm Enzymes	1
Utilization of Bioactive Silk Protein in the Development of Optical Devices: Recent Advancements and Applications	1
Mitochondrial Targeting Peptide-based Nanodelivery for Cancer Treatment	1
Reduced Level of Prolylhydroxyproline in the Nail Clippings of Oral Cancer Patients and its Role as an Activator of Phospholipase C-β2	1
Bioactive Antioxidant Peptides as Novel Natural Interventions for Cardiometabolic Disorders: Mechanistic Insights and Phytotherapeutic Potential	1
Advancing Diabetic Wound Care: Topical Transferosomal Insulin Delivery for Improved Healing	1
Comparative Study of Lactogenic Effect and Milk Nutritional Density of Oral Galactagogue in Female Rabbit	1
Recent Advances in Co-Condensation and Co-Aggregation of Amyloid Proteins Linked to Neurodegenerative Diseases	1
1 H NMR-Based Metabolomics Survey in Breast Cancer Cell Line Treated by Chimera Alpha - Fetoprotein (AFP) Peptide	1
Corrigendum to: β-Barrel Membrane Bacterial Proteins: Structure, Function, Assembly and Interaction with Lipids	1
Acknowledgements to Reviewers	1
A Novel Peptide COX52-69 Inhibits High Glucose-induced Insulin Secretion by Modulating BK Channel Activity	1
Biomarker Revolution in Choriocarcinoma: Beyond β-hCG - Emerging Tools for Diagnosis, Prognosis & Therapeutic Monitoring	1
Effects of the Amyotrophic Lateral Sclerosis-related Q108P Mutation on the Structural Ensemble Characteristics of CHCHD10	1
Exploring the Role of Unconventional Post-Translational Modifications in Cancer Diagnostics and Therapy	1
TEAD4 Identified as a Potential Biomarker for Gastric Cancer Via Genes Associated with Liquid-Liquid Phase Separation	1
Clustering-based Method for Constructing the Phase Diagram of the van der Waals Model Fluid	1
Unveiling the Emerging Role of Klotho: A Comprehensive Narrative Review of an Anti-aging Factor in Human Fertility	1
Intercellular Interactions Mediated by HGF And TGF-Β Promote the 3D Spherical and Xenograft Growth of Liver Cancer Cells	1
Neuropeptide Y Receptor Modulators in Gut Physiology and Therapy	1
Reduced Tumor Volume and Increased Necrosis of Human Breast Tumor Xenograft in Mice Pretreated by a Cocktail of Three Specific Anti-HER2 scFvs	1
An In-Depth Study of Circular RNAs Related to Breast Cancer Treatment and their Implications	1
The Role of Lactate in Ischemic Stroke: As an Energy Source and Signaling Molecule	1
Exercise and Metabolic Health: The Emerging Roles of Novel Exerkines	1
Polyaromatic Hydrocarbon Specific Ring Hydroxylating Dioxygenases: Diversity, Structure, Function, and Protein Engineering	1
The Disulfide Bond-Mediated Cyclization of Oral Peptides	1
PI3K Signaling Pathways as a Molecular Target for Glioblastoma Multiforme	1
Myotoxicity of Crotoxin on C2C12 Myoblasts and its Inhibition by Crotalus Neutralizing Factor versus Enhanced Resistance in Myotubes: Exploring Toxicity and Membrane Potential	1
Diet-induced Obesity: Pathophysiology, Consequences and Target Specific Therapeutic Strategies	1
Radiolabeled-NeoB: A Dual-Action Diagnostic and Therapeutic Agent Targeting Gastrin-Releasing Peptide Receptors in Cancer	1
Critical Role of Calcitonin Gene-related Peptide (CGRP) in the Microbiome-gut-brain Axis	1
Advancements of the CRISPR/Cas9 System in the Treatment of Liver Cancer	1
The Role of NF-κB in Myocardial Ischemia/Reperfusion Injury	1
In-Situ Synthesis of Silver Nanoparticle within Self-Assembling Ultrashort Peptide Hydrogel as Antibacterial with Wound Healing Properties	1
Transforming Medicine: Advances in Gene Therapy, Immunotherapy, and Targeted Cures	1
Engineering Strategies for Hyaluronan Synthesis: A Review of Enzyme Modifications, Strain Selection, and Molecular Weight Control	1
Circular RNAs: Insights into Clinical and Therapeutic Approaches for Various Cancers	1
Immuno-informatic Prediction of B and T cell Epitopes of Cysteine Protease Allergen from Phaseolus vulgaris with Cross-reactive Potential and Population Coverage	1
Current Stage and Future Perspectives for Homology Modeling, Molecular Dynamics Simulations, Machine Learning with Molecular Dynamics, and Quantum Computing for Intrinsically Disordered Proteins and P	1
Heparin Oligosaccharides as Vasoactive Intestinal Peptide Inhibitors via their Binding Process Characterization	1
In-silico and In-vivo Investigations Reveal Ameliorative Potential of Myricetin Against Doxorubicin-induced Myocardial Damage via Modulation of NF-κB Signaling Pathway	1
A Review of the Leishmanicidal Properties of Lectins	1
Compelling Cyclic Peptide Scaffolds for Antitubercular Action: An Account (2011-21) of the Natural Source	1
A Review of the Common Neurodegenerative Disorders: Current Therapeutic Approaches and the Potential Role of Bioactive Peptides	1
A2 Milk: The Impact of Genetic Variation in Milk Protein on Human Health	1