Current Pharmaceutical Biotechnology

Article	Citations
Acknowledgement to Reviewers	81
Strategy of Virtual Screening based Discovery of HSP90 C-terminal Inhibitors and Network Pharmacological Analysis	47
Potential Pathogens Associated with Colorectal Cancer	47
Spray Drying: A Promising Technique for Inhalable Vaccine Development	45
Tryptophan Stability and Palatability in the Food Formulation: A Review	43
Genotoxic Impurities in Critical Analysis of Product Development: Recent Advancements, Patents, and Current Challenges	40
Exploring Therapeutic Frontiers: Unveiling the Potential of Natural Diterpenoid Derivatives in Addressing Neurological Disorders	35
Foldable/Expandable Gastro-retentive Films Based on Starch and Chitosan as a Carrier For Prolonged Release of Resveratrol	34
Protective Role of Glibenclamide and Magnesium Sulfate in Fructoseinduced Type 2 Diabetes Mellitus	32
Systematic Review on Herbal Preparations for Controlling Visceral Hypersensitivity in Functional Gastrointestinal Disorders	31
An Exploration of Organoid Technology: Present Advancements, Applications, and Obstacles	31
Nerolidol-potential Therapeutic Agent for Various Neurological Disorders via its Antioxidative Property	29
Review on Natural Bioactive Products as Radioprotective Therapeutics: Present and Past Perspective	28
Hydrogel Breakthroughs in Biomedicine: Recent Advances and Implications	26
FDA-approved CAR T-cell Therapy: A Decade of Progress and Challenges	26
Polygonati Rhizoma Alleviates Vascular Dementia through Regulating Microglial Polarization Transitions Mediated by NF-κB/NLRP3 Pathway	25
Xiaoyao Pill Improves the Affective Dysregulation of Sleep-deprived Female Mice by Inhibiting Brain Injury and Regulating the Content of Monoamine Neurotransmitter	25
Pharmacological Action and Research Progress of Taraxasterol	24
A Review on Edible Vaccines and Biopharmaceutical Products from Plants	24
Novel Leflunomide Analog, UTLOH-4e, Ameliorates Gouty Arthritis Induced by Monosodium Urate Via NF-κB/NLRP3 Signaling Pathway	23
WITHDRAWN: Current Synopsis on siRNA Therapeutics as a Novel Anti- Cancer and Antiviral Strategy: Progress and Challenges	23
Identification of Novel Drug Candidates for the Inhibition of Catalytic Cleavage Activity of Coronavirus 3CL-like Protease Enzyme	23
Development of Daruharidra (Berberis aristata) Based Biogenic Cadmium Sulfide Nanoparticles: Their Implementation as Antibacterial and Novel Therapeutic Agents against Human Breast and Ovarian Cancer	23
Evolving Advances in the Cosmetic use of Probiotics and Postbiotics: Health, Regulatory and Marketing Aspects	22
Molecular Mechanisms of Immune Resistance in Pancreatic Cancer:An Update	22

Nanogels as Drug Delivery Carrier: A Narrative Review on Formulation Techniques, Characterization, Applications and Patents	22
Research Progress on the Effect and Mechanism of Gene Transfection in Reducing the Inflammatory Response of Atherosclerosis	21
Therapeutic Path to Triple Knockout: Investigating the Pan-inhibitory Mechanisms of AKT, CDK9, and TNKS2 by a Novel 2-phenylquinazolinone Derivative in Cancer Therapy- An In-silico Investigation Thera	21
Pharmacogenomic-Based GWAS Meta-Analyses Coupled with Genetic and Epigenetic Liability Testing Connects Facial and Emotional Recognition Systems to Spectrum Disorders, Schizophrenia, Depression, and A	21
Protective Effects of Curcumin against Nephrotoxicity in Male Rats after Chronic Exposure to Chlorpyrifos	20
Development and Characterization of an Anti-PD-L1 Immunotoxin for Targeted Cancer Therapy	20
Medicinal Plants with Anti-dengue and Immunomodulatory Activity	20
The Cross-talk of Non-coding RNAs and Inflammation in Human Cancer	19
Anti-cancer Virotherapy in Russia: Lessons from the Past, Current Challenges and Prospects for the Future	19
Beta-glucans is a Potential Inhibitor of Ovarian Cancer: Based on Molecular and Biological Aspects	19
Antisense Agents against Antibiotic-resistant Bacteria	18
Advances in Colon-targeted Drug Delivery Systems: Innovative Strategies for Treating Colonic Disorders and Prospects for the Future	18
Layer-by-layer Polymeric Deposition as an Efficient Strategy to Sustain Drug Release	18
The Role of Monosodium Glutamate (MSG) in Epilepsy and other Neurodegenerative Diseases: Phytochemical-based Therapeutic Approa-ches and Mechanisms	18
Role of Protein Ubiquitination and HIF Signaling in the Evolution of Hypoxic Breast Cancer	17
Clinical and Prognostic Implications of an Alternative Splicing-related Risk Model Based on TP53 Status in Breast Cancer	17
Green Nanomaterials: A Road Map to Safe Nanotechnology	17
The Phytochemical and Pharmacological Properties of Citrus sinensis ‘Maltese Half-blood’ Essential Oil Peels Extracted and Optimized by Response-surface Methodology	17
Participation of Lens Proteins and miRs in Traumatic and Inheritance Cataract: A Review on Diagnostic and Therapeutic Approaches for Cataract Management	17
Proteolytic Profiles of Aspergillus caespitosus, A. jensenii and A. neotritici,and a Novel Peptidase with Plasmin-like Activity for Biomedicine andPharmacology	17
Optimization of Phloretin-loaded Nanospanlastics for Targeting of FAS/SREBP1c/AMPK/ OB-Rb Signaling Pathway in HFD-induced Obesity	17
Genome Editing Approaches Using Zinc Finger Nucleases (ZFNs) for the Treatment of Motor Neuron Diseases	16
Flavonoids as Antimicrobial Agents: A Comprehensive Review of Mechanisms and Therapeutic Potential	16
Clinical Efficacy of Probiotics on Oral Health: A Systematic Review of Clinical Trials	15
Isolation and Identification of Bioactive Compounds with Antimicrobial Activity from Marine Facultative Anaerobe, Bacillus subtilis	15
Recent Advances in Immunotherapy and Targeted Therapy of Triple Negative Breast Cancer	15
The Effects of 1,8-Cineole Treatment on Benign Prostatic Hyperplasia in Rats	15
Recent Developments and Applications of Biocatalytic and Chemoenzymatic Synthesis for the Generation of Diverse Classes of Drugs	14
Uterine Biosynthesis through Tissue Engineering: An Overview of Current Methods and Status	14
LTBP1 Gene Expression in the Cerebral Cortex and its Neuroprotective Mechanism in Mice with Postischemic Stroke Epilepsy	14
Innovative Utilization of Endolysins for Future Battle Against Superbugs	14
Emerging Therapeutic Approaches Targeting Ferroptosis in Cancer: Focus on Immunotherapy and Nanotechnology	14
The Hepatoprotective Effects of Ginsenoside from Ginseng: A Review of Molecular Mechanisms and Therapeutic Potentials	14
Liuwei Dihuang Decoction Drug-containing Serum Attenuates Transforming Growth Factor-β1-induced Epithelial-mesenchymal Transition in HK-2 Cells by Inhibiting NF-κB/Snail Signaling Pathway	14
Engineering Platelet Membrane Imitating Nanoparticles for Targeted Therapeutic Delivery	14
Rational Design and Evaluation of the Recombinant Multiepitope Protein for Serodiagnosis of Rubella	14
Biomimetic Fe3O4 Nanozymes Promote Apoptosis in Breast Cancer Cell Lines via Free Radical Scavenging and Inhibition of RelA/p65	14
TP508 Promotes Bone Regeneration on Distraction Osteogenesis via the Activation of Wnt/β-catenin Signaling Pathway	14
The Cutting-edge of CRISPR for Cancer Treatment and its Future Prospects	14
Poly(Lactic-co-glycolic Acid Nanoparticles Loaded with Docetaxel and Coated with Chitosan, Carboxymethyl Chitosan, or Glycol Chitosan	14
NF-κB as a Potential Target for the Treatment and Prevention of Mucositis	14
DBX2 Promotes Glioblastoma Cell Proliferation by Regulating REST Expression	14
Biotechnological Breakthroughs in Resveratrol Synthesis and Health Advancements	14
NK Cell-Based Immunotherapy: Pioneering a New Era in Cancer Treatment	14
Analysis of the Molecular Mechanism of Comorbidity Genes Between Breast Cancer and Depression	14
Exploring the Therapeutic Potential of Flavonoids in the Management of Cancer	14
TiO2 Nanoparticles in Cancer Therapy as Nanocarriers in Paclitaxel’s Delivery and Nanosensitizers in Phototherapies and/or Sonodynamic Therapy	13
miR-199b-5p-AKAP1-DRP1 Pathway Plays a Key Role in ox-LDL-induced Mitochondrial Fission and Endothelial Apoptosis	13
A Comprehensive Review on Preclinical Alzheimer's Disease Models: Evaluating their Clinical Relevance	13
Understanding Mechanisms and Key Factors Influencing Melanogenesis for the Management of Melasma: An Updated Review	13

Unveiling the Therapeutic Potential of Pinostrobin in Alzheimer’s and Parkinson’s Disease Based on Oxidative Stress and Mitochondrial Dysfunction	13
Strategies Employed to Evade the Host Immune Response and the Mechanism of Drug Resistance in Mycobacterium tuberculosis: In Search of Finding New Targets	13
DHA and Cancer: The Uncharted Territory of Nutritional Oncology	12
Single Nucleotide Polymorphisms (SNPs) in the Shadows: Uncovering their Function in Non-Coding Region of Esophageal Cancer	12
Structure, Function, and Physicochemical Properties of Pore-forming Antimicrobial Peptides	12
Solvent Bar Microextraction Combined with HPLC-DAD for Simultaneous Determination of Diuretics in Human Urine and Plasma Samples	12
Lactate as a Metabolic Regulator in the Tumor Microenvironment: Linking Immunosuppression to Epigenetic Reprogramming	12
Quercetin Promotes the Repair of Mitochondrial Function in H9c2 Cells Through the miR-92a-3p/Mfn1 Axis	11
Nanoparticles as Delivery Vehicles for Vaccines: The Use of Gold Nanoparticles	11
Acknowledgement to Reviewers	11
Montelukast Inhibits Lung Cancer Cell Migration by Suppressing Cysteinyl Leukotriene Receptor 1 Expression In vitro	11
Intestinal Epithelial METTL3 Deficiency Exacerbates Sepsis-Induced Barrier Injury via NF-κB/MLCK Pathway and the Protective Role of Curcumin	11
Nanotechnology-powered Meningitis Therapies: Lipid Nanoparticles Lead the Way	11
Self-emulsifying Drug Delivery Systems: Concept to Applications, Regulatory Issues, Recent Patents, Current Challenges and Future Directions	11
Investigating the Impact of Covalent and Non-covalent Binding Modes of Inhibitors on Bruton’s Tyrosine Kinase in the Treatment of B Cell Malignancies - Computational Insights	11
Insights on Quercetin Therapeutic Potential for Neurodegenerative Diseases and its Nano-technological Perspectives	11
Unconventional Remedies for Squamous Cell Carcinoma: A Journey into Alternative Treatments	11
Influence of Nanomedicine as a Smart Weapon for Multidrug Resistance in Cancer Therapy	11
Biotechnological Advances in Enzymatic Hydrolysis and Fermentation for Edible Insects: Functionality, Acceptability and Safety	11
Meet the Editorial Board Member	10
Antifungal Biofilm Strategies: A Less Explored Area in Wound Management	10
Noncoding RNAs in Cancer Theranostics: From Molecular Basis to Therapeutic Implications	10
Graft Copolymers of Polysaccharide: Synthesis Methodology and Biomedical Applications in Tissue Engineering	10
Pubescine as a Novel Antibacterial Agent Against Vancomycin-Resistant Enterococcus: Growth Inhibition, Antibiotic Synergy, and Anti-BiofilmActivity	10
The Effects of Probiotics, Prebiotics and Synbiotics on Wound Infection: A Systematic Review	10
Anti-Cancer Properties and Mechanistic Insights of Dihydroquercetin	10
PhytoCAT: A Comprehensive Data Repository of PhytoChemicals for Affordable Breast Cancer Therapeutics	10
Anti-Mullerian Hormone Induces Foxo1 and Sirt1 Genes Expression in Mouse Ovary	10
Effects of Autologous Immunotherapy on Islet Metabolism and T Cell Immunity in Type 2 Diabetic Rabbits	10
The Natural Product Oridonin as an Anticancer Agent: Current Achievements and Problems	10
Advancements in COVID-19 Testing: An In-depth Overview	10
Exploring the Impact of Curcumin and Carbon Nanotubes on BetaAmyloid Peptide Dimer: Insights from Molecular Dynamics Simulation and Density Functional Theory Methods	10
Potential of the β-Myrcene Rich Essential Oil from Astronium Urundeuva (M.Allemão) Engl. (Anacardiaceae) to Potentiate Fluconazole Activity andInhibit Morphological Transition in Candida Species	9
Selenium Alleviates Oxidative Stress and Inflammation to Promote Postpartum Uterine Recovery via GPX1/GPX4/NRF2 Pathway in Mice	9
The Role of Immunosenescence and Inflammaging in the Susceptibility of Older Adults to SARS-CoV-2 Infection	9
Effect of Nigella sativa Intake on Oxidative Stress and Inflammation in Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-analysis of Randomized Controlled Trials	9
Cancer Stem Cells and Angiogenesis: Exploring the Tumor Microenvironment and Therapeutic Strategies in Lung Cancer	9
Intestinal Epithelial Cell-specific Knockout of METTL3 Aggravates Intestinal Inflammation in CLP Mice by Weakening the Intestinal Barrier	9
Predicting Inhibitor Development in Hemophilia ‘A’ using Machine Learning: A Comprehensive Approach to Data Preprocessing, Balancing, and Biomarker Identification Using AI on the CHAMP Dataset	9
Immunoglobulins: Mechanistic Approaches in Moderation of Various Inflammatory and Anti-inflammatory Pathways	9
Production of Recombinant Human Hybrid Ferritin with Heavy Chain and Light Chain in Escherichia coli and its Characterization	9
Biosynthesis and Detection of Domoic Acid from Diatom Pseudo-nitzschia: A Review	9
Significant Interaction between Melatonin and Titanium Bone Implants: Available Evidence and Future Research Directions	9
A Review of miRNA Regulation in Japanese Encephalitis (JEV) Virus Infection	9
Liquid Biopsy and Non-small-cell Lung Cancer: Expecting More Fluid Management of Patients	9
Traditional Chinese Medicine-based Treatment in Cardiovascular Disease: Potential Mechanisms of Action	9
A Roadmap Towards the Identification and Validation of Conserved T Cell Epitope Regions in Viral Pathogen Families with Pandemic Potential	9
Antioxidative and Anti-photooxidative Potential of Interruptins from the Edible Fern Cyclosorus terminans in Human Skin Cells	9
The Potential of Probiotics for Treating Skin Disorders: A Concise Review	9
Potential of Flavonoids as Promising Phytotherapeutic Agents to Combat Multidrug-Resistant Infections	9
Construction and Validation of T‐cell Exhaustion‐related Gene Signature for Predicting Prognosis in Diffuse Large B-cell Lymphoma	9
In vitro Antioxidant and Antimicrobial Studies of Ethanolic Plant Extracts of P. granatum, O. stamineus, A. bilimbi, M. nigra, and E. longifolia	9
Wound Healing: An Overview of Wound Dressings on Health Care	9
Nanostructured Lipid Carriers Mediated Drug Delivery to Posterior Segment of Eye and their In-vivo Successes	9
Synergistic Effects of Lactobacillus acidophilus and Balanites aegyptiaca in Managing Hyperglycemia, Oxidative Stress, and Inflammation in DiabeticRats	8
Meet the Editorial Board Member	8
BAAE-AgNPs Improve Symptoms of Diabetes in STZ-induced Diabetic Rats	8
The MAP2K2 Gene as Potential Diagnostic Marker in Monitoring Adalimumab Therapy of Psoriatic Arthritis	8
The Biological Effects of Nano-curcumins against Drugs and Chemicals-Induced Nephrotoxicity: A Systematic Review	8
Bioactive Compounds from Vicia sativa L. and Vicia monantha Retz. with Unveiling Antiviral Potentials in Newly Green Synthesized CdO Nanoparticles	8
HYQTD Drug-containing Serum Alleviates H 2 O 2 -induced Endothelial Oxidative Damage by Increasing	8
Recent Nanosolutions Based on Green Propolis Presenting Useful Medical Applications	8
Advances and Challenges of Microneedle Assisted Drug Delivery for Biomedicals Applications: A Review	8
Nanoparticle Delivery of Active Traditional Chinese Medicine Ingredients: A New Strategy for the Treatment of Liver Cancer	8
Biosynthesized Cerium Oxide Nanoparticles CeO2NPs: Recent Progress and Medical Applications	8
Protective Role of Coffee in Thioacetamide-induced Nephrotoxicity:A Study in Rats	8
Drug Repositioning Using Computer-aided Drug Design (CADD)	8
Synthesis, Characterization, Acute Dermal Toxicity, Anti-inflammatory, and Wound Healing Potential of Biogenic Silver Nanoparticles in Balb C Mice	8
Preparation and efficacy validation of dihydromyricetin nanoliposomes.	8
Flavonoids in Autoimmune Diseases: Mechanisms, Clinical Evidence, and Future Directions	8
Profiling of Biologically Active Metabolites of Spergula fallax L. Using High-resolution UPLC-QTOF-MS	8
The Combination of Baicalin with Knockdown of mir148a Gene Suppresses Cell Viability and Proliferation and Induces the Apoptosis and Autophagy of Human Glioblastoma Multiforme T98G and U87MG Cells	8
A Comprehensive Pan-cancer Analysis Identified that TRIB3 was Associated with Immune Cell Infiltration and Poor Prognosis	8
FLG Gene Mutation Up-regulates the Abnormal Tumor Immune Response and Promotes the Progression of Prostate Cancer	8
Dendrimers-Based Hydrogels and Nanogels for Drug Delivery	8
In vitro Antileishmanial Activity and In silico Molecular Modeling Studies of Novel Analogs of Dermaseptins S4 and B2	8
Structural Insights into the Role of Pseudouridimycin Binding in Disruption of Bacterial RNA Polymerase Bridge Helix Conformational Arrangement	8
Herbal Drugs Inducing Autophagy for the Management of Cancer: Mechanism and Utilization	8
Phytoactive Molecules and Nanodelivery Approaches for Breast Cancer Treatment: Current and Future Perspectives	8
Recent Developments in Nanotechnology and Immunotherapy for the Diagnosis and Treatment of Pancreatic Cancer	8

Cancer Antibody Engineering: Comparison of Mammalian, Yeast, Bacterial, Plants, Cell-free and Hybridoma Expression Systems	8
A New Risk Model based on the Machine Learning Approach for Prediction of Mortality in the Respiratory Intensive Care Unit	8
Discovery of New Natural Phytocompounds: The Modern Tools to Fight Against Traditional Bacterial Pathogens	8
Recent Advances in Biomedical Applications of Biogenic Nanomaterials	8
Emerging Nanotechnology Involved in Skin Cancer: Pathogenesis, Biomarkers, Ethosomal Formulation and Future Perspective	8
Medicinal Herbs from Phytoinformatics: An Aid for Skin Burn Management	7
Concomitant Expression of CD39, CD69, and CD103 Identifies Antitumor CD8+ T Cells in Breast Cancer Implications for Adoptive Cell Therapy	7
Multiple Mutations on α, β and γ Domains of Streptokinase Lead to the Generation of Highly Efficient Cysteine Analogues with Promising Features	7
Biofilm Formation in Mycobacterial Genus; Mechanism of Biofilm Formation and Anti-mycobacterial Biofilm Agents	7
Antifungal Resistance in Vaginal Candidiasis Among Reproductive-age Women: A Review	7
The Role of Cuproptosis Key Factor FDX1 in Gastric Cancer	7
New Era on Combining Both Imaging and Drug Delivery to Treat Cancer	7
Interaction Between Staphylococcus aureus and Microbiota: Invasion orCommensalism	7
Protective Effect of Chrysin Against Chlorpyrifos-induced Hepatotoxicity in Rats: Biochemical and Histopathological Approaches in a Sub-chronic Study	7
Establishing a Novel Pyroptosis-related Gene Signature and Predicting Chemical Drugs for Papillary Thyroid Cancer	7
Inhibition of Xanthine Oxidase by 4-nitrocinnamic Acid: In Vitro and In Vivo Investigations and Docking Simulations	7
Application of Nanotechnology to Develop Carrageenan-based Films and Coatings as Carriers for Essential Oils	7
The Causal Role of Uterine Fibroid in Keloid and Hypertrophic Scar: A Bidirectional Mendelian Randomization Study on European Populations	7
Management of Colorectal Cancer Using Nanocarriers-based Drug Delivery for Herbal Bioactives: Current and Emerging Approaches	7
Meet the Editorial Board Member	7
Nanoengineered Therapeutic Scaffolds for Burn Wound Management	7
Intracellular Trafficking Kinetics of Nucleic Acid Escape from Lipid Nanoparticles via Fluorescence Imaging	7
Biochemical Screening, In-vitro and In-silico Characterization of Citrullus colocynthis Fruit Extracts: A Combined Experimental and Computation Study	7
LncRNA/CircRNA-miRNA-mRNA Axis in Atherosclerotic Inflammation: Research Progress	7
A Double-blind Randomized Split-mouth Clinical Trial on a Hemostatic Dental Material Containing Aloe Vera Nanoparticles: The Effects on Pain and Occurrence of Dry Socket after Tooth Extraction	7
The Gut Health Revolution: Herbs and Dietary Phytochemicals in Balancing Gut Microbiota for Optimal Human Health	7
Plant Fiber Composites for Biomedical Applications: Advances and Prospective	7
Nano-combination for Reviving the Activity of Fluconazole against Rhizopus delemar	7
Diagnosis of Canine Visceral Leishmaniasis by Flow Cytometry Serology using the rMELEISH Multiepitope Antigen Coupled in a Functional Bead	7
Antiviral Effect of Ferula Plants and their Potential for Treatment of COVID-19: A Comprehensive Review	7
Integrated Serum Pharmacochemistry, Network Pharmacology, and Molecular Docking to Study the Mechanism of Rhubarb against Atherosclerosis	7
Recent Advancements in Nanoparticles-based Approaches for theTheranostics of Glioblastoma Multiforme	7
New Insights into Pharmaceutical Nanocrystals for the Improved Topical Delivery of Therapeutics in Various Skin Disorders	7
Application of Mathematical Model in Basic Research and Product Manufacturing of Traditional Chinese Medicine	7
Long Non-coding RNA DLEU1 Promotes Progression of Osteoarthritis via miR-492/TLR8 Axis	7
Advances in the Mechanism and Applications of Stimulus-Responsive DNA Hydrogels	7
Artificial Intelligence Revolution in Pharmaceutical Sciences : Advancements, Clinical Impacts, and Applications	7