Current Pharmaceutical Biotechnology

Article	Citations
Acknowledgement to Reviewers	62
Strategy of Virtual Screening based Discovery of HSP90 C-terminal Inhibitors and Network Pharmacological Analysis	44
A Review on Edible Vaccines and Biopharmaceutical Products from Plants	41
Nerolidol-potential Therapeutic Agent for Various Neurological Disorders via its Antioxidative Property	40
Foldable/Expandable Gastro-retentive Films Based on Starch and Chitosan as a Carrier For Prolonged Release of Resveratrol	39
Role of Medicinal Plants against Neurodegenerative Diseases	38
The Rhodamine B-encrypted Vipericidin Peptide, RhoB-Ctn[1-9], Displays In vitro Antimicrobial Activity Against Opportunistic Bacteria and Yeasts	38
Review on Natural Bioactive Products as Radioprotective Therapeutics: Present and Past Perspective	32
Bacteriophages: from Isolation to Application	30
Systematic Review on Herbal Preparations for Controlling Visceral Hypersensitivity in Functional Gastrointestinal Disorders	30
Pharmacological Action and Research Progress of Taraxasterol	30
Hydrogel Breakthroughs in Biomedicine: Recent Advances and Implications	29
Is Hospital Autopsy Auditing Suitable for Clinical Risk Manage ment? Actualities and Perspectives of Auditing in the Autopsy Room Following Italian Law 24/2017 on Patient Safety	29
Exploring Therapeutic Frontiers: Unveiling the Potential of Natural Diterpenoid Derivatives in Addressing Neurological Disorders	27
Genotoxic Impurities in Critical Analysis of Product Development: Recent Advancements, Patents, and Current Challenges	27
Xiaoyao Pill Improves the Affective Dysregulation of Sleep-deprived Female Mice by Inhibiting Brain Injury and Regulating the Content of Monoamine Neurotransmitter	27
An Exploration of Organoid Technology: Present Advancements, Applications, and Obstacles	27
Diagnostic Accuracy and Validity of Serological and Molecular Tests for Hepatitis B and C	26
Astaxanthin Attenuates Adiponectin, Calprotectin, miRNA222 and miRNA378 in Obesity induced by High-Fat Diet in Rats	26
Spray Drying: A Promising Technique for Inhalable Vaccine Development	25
Tryptophan Stability and Palatability in the Food Formulation: A Review	25
Polygonati Rhizoma Alleviates Vascular Dementia through Regulating Microglial Polarization Transitions Mediated by NF-κB/NLRP3 Pathway	24
Potential Pathogens Associated with Colorectal Cancer	23
FDA-approved CAR T-cell Therapy: A Decade of Progress and Challenges	22
Development of Daruharidra (Berberis aristata) Based Biogenic Cadmium Sulfide Nanoparticles: Their Implementation as Antibacterial and Novel Therapeutic Agents against Human Breast and Ovarian Cancer	22

WITHDRAWN: Current Synopsis on siRNA Therapeutics as a Novel Anti- Cancer and Antiviral Strategy: Progress and Challenges	21
Drug Repurposing: An Alternative Strategy to Treat COVID-19	21
Development and Characterization of an Anti-PD-L1 Immunotoxin for Targeted Cancer Therapy	21
Therapeutic Path to Triple Knockout: Investigating the Pan-inhibitory Mechanisms of AKT, CDK9, and TNKS2 by a Novel 2-phenylquinazolinone Derivative in Cancer Therapy- An In-silico Investigation Thera	21
Novel Leflunomide Analog, UTLOH-4e, Ameliorates Gouty Arthritis Induced by Monosodium Urate Via NF-κB/NLRP3 Signaling Pathway	21
Identification of Novel Drug Candidates for the Inhibition of Catalytic Cleavage Activity of Coronavirus 3CL-like Protease Enzyme	20
Evolving Advances in the Cosmetic use of Probiotics and Postbiotics: Health, Regulatory and Marketing Aspects	19
Nanogels as Drug Delivery Carrier: A Narrative Review on Formulation Techniques, Characterization, Applications and Patents	19
Protective Effects of Curcumin against Nephrotoxicity in Male Rats after Chronic Exposure to Chlorpyrifos	18
The Role of Monosodium Glutamate (MSG) in Epilepsy and other Neurodegenerative Diseases: Phytochemical-based Therapeutic Approa-ches and Mechanisms	18
Isolation and Identification of Bioactive Compounds with Antimicrobial Activity from Marine Facultative Anaerobe, Bacillus subtilis	18
Medicinal Plants with Anti-dengue and Immunomodulatory Activity	18
Synthesis of Silymarin-Gold Nanoparticle Conjugate and Analysis of its Liver-Protecting Activity	18
Molecular Mechanisms of Immune Resistance in Pancreatic Cancer:An Update	18
Antisense Agents against Antibiotic-resistant Bacteria	17
The Phytochemical and Pharmacological Properties of Citrus sinensis ‘Maltese Half-blood’ Essential Oil Peels Extracted and Optimized by Response-surface Methodology	17
Clinical Efficacy of Probiotics on Oral Health: A Systematic Review of Clinical Trials	17
The Cross-talk of Non-coding RNAs and Inflammation in Human Cancer	17
Participation of Lens Proteins and miRs in Traumatic and Inheritance Cataract: A Review on Diagnostic and Therapeutic Approaches for Cataract Management	17
Anti-cancer Virotherapy in Russia: Lessons from the Past, Current Challenges and Prospects for the Future	17
Layer-by-layer Polymeric Deposition as an Efficient Strategy to Sustain Drug Release	16
Recent Developments and Applications of Biocatalytic and Chemoenzymatic Synthesis for the Generation of Diverse Classes of Drugs	16
Role of Protein Ubiquitination and HIF Signaling in the Evolution of Hypoxic Breast Cancer	15
Seventeen-Year Medical Professional Liability Experience in a Level III University Hospital	15
Proteolytic Profiles of Aspergillus caespitosus, A. jensenii and A. neotritici,and a Novel Peptidase with Plasmin-like Activity for Biomedicine andPharmacology	14
Beta-glucans is a Potential Inhibitor of Ovarian Cancer: Based on Molecular and Biological Aspects	14
NF-κB as a Potential Target for the Treatment and Prevention of Mucositis	14
The Effects of 1,8-Cineole Treatment on Benign Prostatic Hyperplasia in Rats	14
Flavonoids as Antimicrobial Agents: A Comprehensive Review of Mechanisms and Therapeutic Potential	14
Optimization of Phloretin-loaded Nanospanlastics for Targeting of FAS/SREBP1c/AMPK/ OB-Rb Signaling Pathway in HFD-induced Obesity	14
Liuwei Dihuang Decoction Drug-containing Serum Attenuates Transforming Growth Factor-β1-induced Epithelial-mesenchymal Transition in HK-2 Cells by Inhibiting NF-κB/Snail Signaling Pathway	14
Clinical and Prognostic Implications of an Alternative Splicing-related Risk Model Based on TP53 Status in Breast Cancer	14
A Comprehensive Review on Preclinical Alzheimer's Disease Models: Evaluating their Clinical Relevance	13
Genome Editing Approaches Using Zinc Finger Nucleases (ZFNs) for the Treatment of Motor Neuron Diseases	13
Green Nanomaterials: A Road Map to Safe Nanotechnology	13
DBX2 Promotes Glioblastoma Cell Proliferation by Regulating REST Expression	13
Recent Advances in Immunotherapy and Targeted Therapy of Triple Negative Breast Cancer	13
Uterine Biosynthesis through Tissue Engineering: An Overview of Current Methods and Status	13
Engineering Platelet Membrane Imitating Nanoparticles for Targeted Therapeutic Delivery	13
miR-199b-5p-AKAP1-DRP1 Pathway Plays a Key Role in ox-LDL-induced Mitochondrial Fission and Endothelial Apoptosis	12
LTBP1 Gene Expression in the Cerebral Cortex and its Neuroprotective Mechanism in Mice with Postischemic Stroke Epilepsy	12
Structure, Function, and Physicochemical Properties of Pore-forming Antimicrobial Peptides	12
Understanding Mechanisms and Key Factors Influencing Melanogenesis for the Management of Melasma: An Updated Review	12
Biotechnological Breakthroughs in Resveratrol Synthesis and Health Advancements	12
The Cutting-edge of CRISPR for Cancer Treatment and its Future Prospects	12
Analysis of the Molecular Mechanism of Comorbidity Genes Between Breast Cancer and Depression	12
Rational Design and Evaluation of the Recombinant Multiepitope Protein for Serodiagnosis of Rubella	12
The Hepatoprotective Effects of Ginsenoside from Ginseng: A Review of Molecular Mechanisms and Therapeutic Potentials	12
TP508 Promotes Bone Regeneration on Distraction Osteogenesis via the Activation of Wnt/β-catenin Signaling Pathway	12
Emerging Therapeutic Approaches Targeting Ferroptosis in Cancer: Focus on Immunotherapy and Nanotechnology	12

Lactate as a Metabolic Regulator in the Tumor Microenvironment: Linking Immunosuppression to Epigenetic Reprogramming	11
Exploring the Therapeutic Potential of Flavonoids in the Management of Cancer	11
Quercetin Promotes the Repair of Mitochondrial Function in H9c2 Cells Through the miR-92a-3p/Mfn1 Axis	11
Single Nucleotide Polymorphisms (SNPs) in the Shadows: Uncovering their Function in Non-Coding Region of Esophageal Cancer	11
Biomimetic Fe3O4 Nanozymes Promote Apoptosis in Breast Cancer Cell Lines via Free Radical Scavenging and Inhibition of RelA/p65	11
DHA and Cancer: The Uncharted Territory of Nutritional Oncology	11
Current Overviews on COVID-19 Management Strategies	11
Strategies Employed to Evade the Host Immune Response and the Mechanism of Drug Resistance in Mycobacterium tuberculosis: In Search of Finding New Targets	11
TiO2 Nanoparticles in Cancer Therapy as Nanocarriers in Paclitaxel’s Delivery and Nanosensitizers in Phototherapies and/or Sonodynamic Therapy	11
Solvent Bar Microextraction Combined with HPLC-DAD for Simultaneous Determination of Diuretics in Human Urine and Plasma Samples	11
The Natural Product Oridonin as an Anticancer Agent: Current Achievements and Problems	11
Investigating the Impact of Covalent and Non-covalent Binding Modes of Inhibitors on Bruton’s Tyrosine Kinase in the Treatment of B Cell Malignancies - Computational Insights	10
Anti-Cancer Properties and Mechanistic Insights of Dihydroquercetin	10
Nanotechnology-powered Meningitis Therapies: Lipid Nanoparticles Lead the Way	10
Self-emulsifying Drug Delivery Systems: Concept to Applications, Regulatory Issues, Recent Patents, Current Challenges and Future Directions	10
Antifungal Biofilm Strategies: A Less Explored Area in Wound Management	10
Nanoparticles as Delivery Vehicles for Vaccines: The Use of GoldNanoparticles	10
Piecing the Fragments Together: Dynamical Insights into the Enhancement of BRD4-BD1 (BET Protein) Druggability in Cancer Chemotherapy Using Novel 8-methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one Derivatives	10
The Effects of Probiotics, Prebiotics and Synbiotics on Wound Infection: A Systematic Review	10
Unconventional Remedies for Squamous Cell Carcinoma: A Journey into Alternative Treatments	10
Biotechnological Advances in Enzymatic Hydrolysis and Fermentation for Edible Insects: Functionality, Acceptability and Safety	10
Montelukast Inhibits Lung Cancer Cell Migration by Suppressing Cysteinyl Leukotriene Receptor 1 Expression In vitro	10
Insights on Quercetin Therapeutic Potential for Neurodegenerative Diseases and its Nano-technological Perspectives	10
Influence of Nanomedicine as a Smart Weapon for Multidrug Resistancein Cancer Therapy	10
Traditional Chinese Medicine-based Treatment in Cardiovascular Disease: Potential Mechanisms of Action	9
Connectivity Map Analysis Identifies Fisetin as a Treatment Compound for Osteoporosis Through Activating the PI3K-AKT Signaling Pathway in Mouse Pre-osteoblastic MC3T3-E1 Cells	9
Exploring the Impact of Curcumin and Carbon Nanotubes on BetaAmyloid Peptide Dimer: Insights from Molecular Dynamics Simulation and Density Functional Theory Methods	9
Advancements in COVID-19 Testing: An In-depth Overview	9
PhytoCAT: A Comprehensive Data Repository of PhytoChemicals for Affordable Breast Cancer Therapeutics	9
Liquid Biopsy and Non-small-cell Lung Cancer: Expecting More Fluid Management of Patients	9
Intestinal Epithelial Cell-specific Knockout of METTL3 Aggravates Intestinal Inflammation in CLP Mice by Weakening the Intestinal Barrier	9
Antioxidative and Anti-photooxidative Potential of Interruptins from the Edible Fern Cyclosorus terminans in Human Skin Cells	9
Graft Copolymers of Polysaccharide: Synthesis Methodology and Biomedical Applications in Tissue Engineering	9
Noncoding RNAs in Cancer Theranostics: From Molecular Basis to Therapeutic Implications	9
Wound Healing: An Overview of Wound Dressings on Health Care	9
Nanostructured Lipid Carriers Mediated Drug Delivery to Posterior Segment of Eye and their In-vivo Successes	9
Anti-Mullerian Hormone Induces Foxo1 and Sirt1 Genes Expression in Mouse Ovary	9
Production of Recombinant Human Hybrid Ferritin with Heavy Chain and Light Chain in Escherichia coli and its Characterization	9
Recent Advances in siRNA Delivery Systems for Prostate Cancer Therapy	9
Proposal for the Application of a Quality Indicator to Medico-legal Consultations in the Field of Medical Liability	9
A Review of miRNA Regulation in Japanese Encephalitis (JEV) Virus Infection	9
Key Performance Indicators in Claims Management: Definition of a Set of Indicators for the Evaluation of the Medico-Legal Activity	9
Meet the Editorial Board Member	9
Pubescine as a Novel Antibacterial Agent Against Vancomycin-Resistant Enterococcus: Growth Inhibition, Antibiotic Synergy, and Anti-BiofilmActivity	9
Bioactive Compounds with Significant Anti-Rheumatoid Arthritis Effect Isolated for the First time from Leaves of Bougainvillea spectabilis	9
Biosynthesis and Detection of Domoic Acid from Diatom Pseudo-nitzschia: A Review	9
A Roadmap Towards the Identification and Validation of Conserved T Cell Epitope Regions in Viral Pathogen Families with Pandemic Potential	9
Selenium Alleviates Oxidative Stress and Inflammation to Promote Postpartum Uterine Recovery via GPX1/GPX4/NRF2 Pathway in Mice	8
In vitro Antioxidant and Antimicrobial Studies of Ethanolic Plant Extracts of P. granatum, O. stamineus, A. bilimbi, M. nigra, and E. longifolia	8
Significant Interaction between Melatonin and Titanium Bone Implants: Available Evidence and Future Research Directions	8
Acknowledgements to Reviewers	8
A New Risk Model based on the Machine Learning Approach for Prediction of Mortality in the Respiratory Intensive Care Unit	8
Development of Apigenin-Loaded Niosomes Using Ecological Probe Sonication Technique for Enhanced Oral Delivery: Application of Box- Behnken Design	8
Emerging Nanotechnology Involved in Skin Cancer: Pathogenesis, Biomarkers, Ethosomal Formulation and Future Perspective	8
Meet the Editorial Board Member	8
The Role of Immunosenescence and Inflammaging in the Susceptibility of Older Adults to SARS-CoV-2 Infection	8
Effect of Nigella sativa Intake on Oxidative Stress and Inflammation in Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-analysis of Randomized Controlled Trials	8
Predicting Inhibitor Development in Hemophilia ‘A’ using Machine Learning: A Comprehensive Approach to Data Preprocessing, Balancing, and Biomarker Identification Using AI on the CHAMP Dataset	8
Biosynthesized Cerium Oxide Nanoparticles CeO2NPs: Recent Progress and Medical Applications	8
Nanotechnology Enabled Solutions to Combat Covid-19: Prevention, Treatment, and Diagnosis	8
BAAE-AgNPs Improve Symptoms of Diabetes in STZ-induced Diabetic Rats	8
Structural Insights into the Role of Pseudouridimycin Binding in Disruption of Bacterial RNA Polymerase Bridge Helix Conformational Arrangement	8
A Comprehensive Pan-cancer Analysis Identified that TRIB3 was Associated with Immune Cell Infiltration and Poor Prognosis	8
Potential of the β-Myrcene Rich Essential Oil from Astronium Urundeuva (M.Allemão) Engl. (Anacardiaceae) to Potentiate Fluconazole Activity andInhibit Morphological Transition in Candida Species	8
Potential of Flavonoids as Promising Phytotherapeutic Agents to Combat Multidrug-Resistant Infections	8
The Potential of Probiotics for Treating Skin Disorders: A Concise Review	8
Immunoglobulins: Mechanistic Approaches in Moderation of Various Inflammatory and Anti-inflammatory Pathways	8
In vitro Antileishmanial Activity and In silico Molecular Modeling Studies of Novel Analogs of Dermaseptins S4 and B2	8
Nanoparticle Delivery of Active Traditional Chinese Medicine Ingredients: A New Strategy for the Treatment of Liver Cancer	8
Herbal Drugs Inducing Autophagy for the Management of Cancer: Mechanism and Utilization	8
Drug Repositioning Using Computer-aided Drug Design (CADD)	8
Intracellular Trafficking Kinetics of Nucleic Acid Escape from Lipid Nanoparticles via Fluorescence Imaging	7
Production of Chemotherapeutic Enzyme L-asparaginase from a Fungal Source	7
Recent Developments in Nanotechnology and Immunotherapy for the Diagnosis and Treatment of Pancreatic Cancer	7
New Era on Combining Both Imaging and Drug Delivery to Treat Cancer	7
Recent Advances in Biomedical Applications of Biogenic Nanomaterials	7
Synergistic Effects of Lactobacillus acidophilus and Balanites aegyptiaca in Managing Hyperglycemia, Oxidative Stress, and Inflammation in DiabeticRats	7
HYQTD Drug-containing Serum Alleviates H2O2-induced Endothelial Oxidative Damage by Increasing Mitochondrial ATP Synthesis and Inhibiting ROS	7
FLG Gene Mutation Up-regulates the Abnormal Tumor Immune Response and Promotes the Progression of Prostate Cancer	7
LncRNA/CircRNA-miRNA-mRNA Axis in Atherosclerotic Inflammation: Research Progress	7

Long Non-coding RNA DLEU1 Promotes Progression of Osteoarthritis via miR-492/TLR8 Axis	7
Antifungal Resistance in Vaginal Candidiasis Among Reproductive-age Women: A Review	7
Integrated Serum Pharmacochemistry, Network Pharmacology, and Molecular Docking to Study the Mechanism of Rhubarb against Atherosclerosis	7
Cancer Antibody Engineering: Comparison of Mammalian, Yeast, Bacterial, Plants, Cell-free and Hybridoma Expression Systems	7
Dendrimers-Based Hydrogels and Nanogels for Drug Delivery	7
Discovery of New Natural Phytocompounds: The Modern Tools to Fight Against Traditional Bacterial Pathogens	7
The MAP2K2 Gene as Potential Diagnostic Marker in Monitoring Adalimumab Therapy of Psoriatic Arthritis	7
Profiling of Biologically Active Metabolites of Spergula fallax L. Using High-resolution UPLC-QTOF-MS	7
Methods of Random Mutagenesis of Aspergillus Strain for Increasing Kojic Acid Production	7
Bioactive Compounds from Vicia sativa L. and Vicia monantha Retz. with Unveiling Antiviral Potentials in Newly Green Synthesized CdO Nanoparticles	7
Synthesis, Characterization, Acute Dermal Toxicity, Anti-inflammatory, and Wound Healing Potential of Biogenic Silver Nanoparticles in Balb C Mice	7
New Insights into Pharmaceutical Nanocrystals for the Improved Topical Delivery of Therapeutics in Various Skin Disorders	7
Protective Effect of Chrysin Against Chlorpyrifos-induced Hepatotoxicity in Rats: Biochemical and Histopathological Approaches in a Sub-chronic Study	7
The Combination of Baicalin with Knockdown of mir148a Gene Suppresses Cell Viability and Proliferation and Induces the Apoptosis and Autophagy of Human Glioblastoma Multiforme T98G and U87MG Cells	7
Protective Role of Coffee in Thioacetamide-induced Nephrotoxicity:A Study in Rats	7
Phytoactive Molecules and Nanodelivery Approaches for Breast Cancer Treatment: Current and Future Perspectives	7
Recent Nanosolutions Based on Green Propolis Presenting Useful Medical Applications	7
The Biological Effects of Nano-curcumins against Drugs and Chemicals-Induced Nephrotoxicity: A Systematic Review	7
Nanoengineered Therapeutic Scaffolds for Burn Wound Management	6
Nano-combination for Reviving the Activity of Fluconazole against Rhizopus delemar	6
Research Progress in Elucidating the Mechanisms Underlying Resveratrol Action on Lung Cancer	6
A Concise Overview of Biosensing Technologies for the Detection of Alzheimer's Disease Biomarkers	6
Application of Nanotechnology to Develop Carrageenan-based Films and Coatings as Carriers for Essential Oils	6
Medicinal Herbs from Phytoinformatics: An Aid for Skin Burn Management	6
Recent Advancements in Nanoparticles-based Approaches for theTheranostics of Glioblastoma Multiforme	6
A Double-blind Randomized Split-mouth Clinical Trial on a Hemostatic Dental Material Containing Aloe Vera Nanoparticles: The Effects on Pain and Occurrence of Dry Socket after Tooth Extraction	6
Nanosponges-road Less Explored Changing Drug Delivery Approach: An Explicative Review	6
Evaluating Potentials of Species Rich Taxonomic Groups in Cosmetics and Dermatology: Clustering and Dispersion of Skin Efficacy of Asteraceae and Ranunculales Plants on the Species Phylogenetic Tree	6
Artificial Intelligence Revolution in Pharmaceutical Sciences: Advancements, Clinical Impacts, and Applications	6
Biochemical Screening, In-vitro and In-silico Characterization of Citrullus colocynthis Fruit Extracts: A Combined Experimental and Computation Study	6
Multiple Mutations on α, β and γ Domains of Streptokinase Lead to the Generation of Highly Efficient Cysteine Analogues with Promising Features	6
Meet the Editorial Board Member	6
Management of Colorectal Cancer Using Nanocarriers-based Drug Delivery for Herbal Bioactives: Current and Emerging Approaches	6
Inhibition of Xanthine Oxidase by 4-nitrocinnamic Acid: In Vitro and In Vivo Investigations and Docking Simulations	6
Plant Fiber Composites for Biomedical Applications: Advances and Prospective	6
Advances in the Mechanism and Applications of Stimulus-Responsive DNA Hydrogels	6
Biofilm Formation in Mycobacterial Genus; Mechanism of Biofilm Formation and Anti-mycobacterial Biofilm Agents	6
Establishing a Novel Pyroptosis-related Gene Signature and Predicting Chemical Drugs for Papillary Thyroid Cancer	6
The Causal Role of Uterine Fibroid in Keloid and Hypertrophic Scar: A Bidirectional Mendelian Randomization Study on European Populations	6
Diagnosis of Canine Visceral Leishmaniasis by Flow Cytometry Serology using the rMELEISH Multiepitope Antigen Coupled in a Functional Bead	6
A Review: Underutilized Plant of Sabah and its Potential Value	6
Meet the Editorial Board Member	6
Biopharmaceutical and Pharmacokinetic Activities of Oxymatrine Determined by a Sensitive UHPLC-MS/MS Method	6
Concomitant Expression of CD39, CD69, and CD103 Identifies Antitumor CD8+ T Cells in Breast Cancer Implications for Adoptive Cell Therapy	6
Changing Trends Towards Herbal Supplements: An Insight into Safety and Herb-drug Interaction	6
Application of Mathematical Model in Basic Research and Product Manufacturing of Traditional Chinese Medicine	6
Gut Microbiota and Human Body Interactions; Its Impact on Health: A Review	6
Antiviral Effect of Ferula Plants and their Potential for Treatment of COVID-19: A Comprehensive Review	6
The Gut Health Revolution: Herbs and Dietary Phytochemicals in Balancing Gut Microbiota for Optimal Human Health	6