Current Drug Metabolism

Article	Citations
2020 FDA Drug-drug Interaction Guidance: A Comparison Analysis and Action Plan by Pharmaceutical Industrial Scientists	71
ADMET Profiling in Drug Discovery and Development: Perspectives of In Silico, In Vitro and Integrated Approaches	36
Salidroside - Can it be a Multifunctional Drug?	30
Polymeric Nanoparticles for Brain Drug Delivery - A Review	27
Tumor Angiogenesis and VEGFR-2: Mechanism, Pathways and Current Biological Therapeutic Interventions	27
Nanostructured Lipid Carriers (NLCs): Nose-to-Brain Delivery and Theranostic Application	24
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs	24
Chemical Metabolism of Xenobiotics by Gut Microbiota	24
Genistein: Its Role in Breast Cancer Growth and Metastasis	23
The Current State of Potential Therapeutic Modalities for Glioblastoma Multiforme: A Clinical Review	23
Germacrone: A Potent Secondary Metabolite with Therapeutic Potential in Metabolic Diseases, Cancer and Viral Infections	21
Biosurfactants as a Novel Additive in Pharmaceutical Formulations: Current Trends and Future Implications	18
Nano Phytomedicine Based Delivery System for CNS Disease	18
Exosome-based Tumor Therapy: Opportunities and Challenges	17
Therapeutics and Research Related to Glioblastoma: Advancements and Future Targets	16
A Review: Effects of Macrolides on CYP450 Enzymes	15
Topical Capsaicin for the Treatment of Neuropathic Pain	15
Tubulin Proteins in Cancer Resistance: A Review	15
Murburn Precepts for Cytochrome P450 Mediated Drug/Xenobiotic Metabolism and Homeostasis	15
Metabolism and Mechanism of Human Cytochrome P450 Enzyme 1A2	15
Metabolite Identification in the Preclinical and Clinical Phase of Drug Development	14
Chloro-s-triazines-toxicokinetic, Toxicodynamic, Human Exposure, and Regulatory Considerations	14
Clinical Pharmacokinetics of Propranolol Hydrochloride: A Review	14
Natural Compounds as Source of Aldose Reductase (AR) Inhibitors for the Treatment of Diabetic Complications: A Mini Review	14
Distribution, Biotransformation, Pharmacological Effects, Metabolic Mechanism and Safety Evaluation of Platycodin D: A Comprehensive Review	14

Metabolism and Interactions of Chloroquine and Hydroxychloroquine with Human Cytochrome P450 Enzymes and Drug Transporters	13
Preclinical Evidence for the Pharmacological Actions of Glycyrrhizic Acid: A Comprehensive Review	13
HMG-CoA Reductase Inhibitors (Statins) and their Drug Interactions Involving CYP Enzymes, P-glycoprotein and OATP Transporters-An Overview	12
Stem Cells in Tumour Microenvironment Aid in Prolonged Survival Rate of Cancer Cells and Developed Drug Resistance: Major Challenge in Osteosarcoma Treatment	12
Metabolism and Pharmacological Mechanisms of Active Ingredients in Erigeron breviscapus	11
Gold Nanoparticles; Potential Nanotheranostic Agent in Breast Cancer: A Comprehensive Review with Systematic Search Strategy	11
Inhibition of Efflux Pumps by Monoterpene (α-pinene) and Impact on Staphylococcus aureus Resistance to Tetracycline and Erythromycin	11
Analysis of the Potential Association of Drug-Metabolizing Enzymes CYP2C9*3 and CYP2C19*3 Gene Variations With Type 2 Diabetes: A Case-Control Study	11
Recent Advances in Biotransformation by Cunninghamella Species	10
The Potential Role of Serum Exosomes in Preeclampsia	10
Research Progress of Herbal Medicines on Drug Metabolizing Enzymes: Consideration Based on Toxicology	10
Prognostic Role of Hedgehog-GLI1 Signaling Pathway in Aggressive and Metastatic Breast Cancers	10
Effect of Nigella sativa and Fenugreek on the Pharmacokinetics and Pharmacodynamics of Amlodipine in Hypertensive Rats	10
Comparison of Bromhexine and its Active Metabolite - Ambroxol as Potential Analgesics Reducing Oxaliplatin-induced Neuropathic Pain - Pharmacodynamic and Molecular Docking Studies	10
Medicinal Plants and Natural Products: More Effective and Safer Pharmacological Treatment for the Management of Obesity	10
Application of Advanced Technologies in Natural Product Research: A Review with Special Emphasis on ADMET Profiling	10
Talin: A Potential Drug Target for Cancer Therapy	10
Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases and their Metabolic Profiling: Part 1	9
Mechanism of the Intestinal Absorption of Six Flavonoids from Zizyphi Spinosi Semen Across Caco-2 Cell Monolayer Model	9
Decoding Novel Mechanisms and Emerging Therapeutic Strategies in Breast Cancer Resistance	9
Absorption, Distribution, Metabolism, and Excretion of Aprocitentan, a Dual Endothelin Receptor Antagonist, in Humans	9
Further Considerations Towards an Effective and Efficient Oncology Drug Discovery DMPK Strategy	9
An Overview of Dietary Supplements on Obesity and Type 2 Diabetes: Efficacy and Mechanisms	9
Recent Advances in Nanotechnology-Based Targeted Therapeutics for Breast Cancer Management	9
A Review on Pharmacokinetic and Pharmacodynamic Drug Interactions of Adrenergic β-blockers with Clinically Relevant Drugs-An Overview	9
Development and Validation of a Sensitive UPLC-Q-TOF-MS/MS for the Measurement of Nine Components in Rat Plasma and Tissues and its Application to Pharmacokinetics and Tissue Distribution Studies with	9
Physiologically-based Pharmacokinetic (PBPK) Modelling of Transporter Mediated Drug Absorption, Clearance and Drug-drug Interactions	8
Naphthalene Toxicity in Clinical Practice	8
Pharmacogenetic Evaluation of Metformin and Sulphonylurea Response in Mexican Mestizos with Type 2 Diabetes	8
Interactions Between Meropenem and Renal Drug Transporters	8
The Role of Metabolism in Toxicity of Polycyclic Aromatic Hydrocarbons and their Non-genotoxic Modes of Action	8
Protective Effects of Grape Seed Proanthocyanidin Extract in Preventing DSS Induced Ulcerative Colitis Based on Pharmacodynamic, Pharmacokinetic and Tissue Distribution	8
Isolation, Docking and In Silico ADME-T Studies of Acacianol: Novel Antibacterial Isoflavone Analogue Isolated from Acacia leucophloea Bark	8
The Metabolism and Pharmacokinetics of Rhein and Aurantio-Obtusin	8
Nanocrystals: An Approachable Delivery System for Anticancer Therapeutics	8
Deciphering the Role of Nanoparticle-based Treatment for Parkinson’s Disease	8
Applications of Machine Learning in Drug Target Discovery	8
An Update on the Recent Advances in Cubosome: A Novel Drug Delivery System	8
Thymoquinone Lipid Nanoparticles Cut the Gordian Knots of Depression via Neuroprotective BDNF and Downregulation of Neuro-inflammatory NF-κB, IL-6, and TNF-α in LPS Treated Rats	8
The Influence of Different Disease States on Rituximab Pharmacokinetics	8
Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases and their Metabolic Profiling - Part 3	7
Changes of Transporters and Drug-metabolizing Enzymes in Nephrotic Syndrome	7
Secondary Metabolites in the Treatment of Diabetes Mellitus: A Paradigm Shift	7
Current Treatment Options for HCC: From Pharmacokinetics to Efficacy and Adverse Events in Liver Cirrhosis	7
Role of Exosomes in the Exchange of Spermatozoa after Leaving the Seminiferous Tubule: A Review	7
Role of Genetic Polymorphisms of Cytochrome P450 2C19 in Pantoprazole Metabolism and Pantoprazole-based Helicobacter pylori Eradication Regimens	7
Effective Cancer Management: Inimitable Role of Phytochemical Based Nano- Formulations	7
Tumor-targeted Drug Delivery by Nanocomposites	7
A Decade’s Review of miRNA: A Center of Transcriptional Regulation of Drugmetabolizing Enzymes and Transporters under Hypoxia	7
Preclinical Study of the Pharmacokinetics of p75ECD-Fc, a Novel Human Recombinant Protein for Treatment of Alzheimer’s Disease, in Sprague Dawley Rats	6

Absorption, Metabolism, Distribution, and Excretion of Letermovir	6
The Genetic Polymorphism of CYP3A4 rs2242480 is Associated with Sirolimus Trough Concentrations Among Adult Renal Transplant Recipients	6
Clinical Application of Thiopurine Pharmacogenomics in Pediatrics	6
Relevance of ABC Transporters in Drug Development	6
Review of the Clinical Pharmacokinetics, Efficacy and Safety of Pembrolizumab	6
Antibiotics as Inhibitor of Glutathione S-transferase: Biological Evaluation and Molecular Structure Studies	6
Pain Allaying Epalrestat-Loaded Lipid Nanoformulation for the Diabetic Neuropathic Pain Interventions: Design, Development, and Animal Study	6
Bibliometric Analysis of Current Drug Metabolism: The Twentieth Anniversary from 2000-2019	6
Recent Advances in Nanotechnology: A Novel Therapeutic System for the Treatment of Alzheimer’s Disease	6
Versatile and Valuable Utilization of Amidohydrolase L-glutaminase in Pharma and Food industries: A Review	6
Study on the Plasma Protein Binding Rate and Compatibility Regularity of the Constituents Migrating to Blood of Simiao Yong’an Decoction	6
Evaluation of the Effects of Maytenus ilicifolia on the Activities of Cytochrome P450 3A and P-glycoprotein	6
Hepatoprotective Role of Berberine on Doxorubicin Induced Hepatotoxicity - Involvement of Cyp	6
Risk Assessment of Veterinary Drug Residues in Meat Products	5
Molecular Modeling Studies on Cytochrome P450-mediated Drug Metabolism	5
Receptor-Mediated Targeting in Breast Cancer through Solid Lipid Nanoparticles and Its Mechanism	5
Recent Patents, Regulatory Issues, and Toxicity of Nanoparticles in Neuronal Disorders	5
Role of Glucose Transporters in Drug Membrane Transport	5
Cytochromes P450: Role in Carcinogenesis and Relevance to Cancers	5
Pharmacokinetic Study of Vadadustat and High-Resolution Mass Spectrometric Characterization of its Novel Metabolites in Equines for the Purpose of Doping Control	5
Rapid Profiling and Identification of Vitexin Metabolites in Rat Urine, Plasma and Faeces after Oral Administration Using a UHPLC-Q-Exactive Orbitrap Mass Spectrometer Coupled with Multiple Data-minin	5
A Novel Nanoformulation of Ellagic Acid is Promising in Restoring Oxidative Homeostasis in Rat Brains with Alzheimer’s Disease	5
Dysfunction of ABC Transporters at the Surface of BBB: Potential Implications in Intractable Epilepsy and Applications of Nanotechnology Enabled Drug Delivery	5
A Unifying Perspective in Blunting the Limited Oral Bioavailability of Curcumin: A Succinct Look	5
Impact of Drug Metabolism/Pharmacokinetics and its Relevance Considering Traditional Medicine-based Anti-COVID-19 Drug Research	5
Modulation of the Drug Resistance by Platonia insignis Mart. Extract, Ethyl Acetate Fraction and Morelloflavone/Volkensiflavone (Biflavonoids) in Staphylococcus aureus Strains Overexpressing Efflux Pu	5
Recent Advances on Antioxidant Identification Based on Machine Learning Methods	5
Predicted Contributions of Flavin-containing Monooxygenases to the N-oxygenation of Drug Candidates Based on their Estimated Base Dissociation Constants	5
Curcumin Nanoemulsions Stabilized with Modified Phosphatidylcholine on Skin Carcinogenesis Protocol	5
Approaches to Address PK-PD Challenges of Conventional Liposome Formulation with Special Reference to Cancer, Alzheimer's, Diabetes, and Glaucoma: An Update on Modified Liposomal Drug Delivery System	4
Simultaneous Method Development and Validation of Anastrozole Along with Piperine: Degradation Studies and Degradants Characterization Using LC-QTOF-ESI-MS Along with In-silico ADMET Prediction	4
Evaluation of Nigerian Medicinal Plants Extract on Human P-glycoprotein and Cytochrome P450 Enzyme Induction: Implications for Herb-drug Interaction	4
Structure of the Blood Brain Barrier and its Role in the Transporters for the Movement of Substrates across the Barriers	4
Advances in Hybrid Vesicular-based Drug Delivery Systems: Improved Biocompatibility, Targeting, Therapeutic Efficacy and Pharmacokinetics of Anticancer Drugs	4
Current Trends for Rationalizing Brain Targeting Nanoparticles in Neurological Disorders (Part-I)	4
Therapeutic Approaches to Amyotrophic Lateral Sclerosis from the Lab to the Clinic	4
The Influence of Kidneys Ion Transport Inhibitors on the Pharmacokinetic and Tumor Uptake Behaviors of a HER2-targeted Small Size Radiolabeled Peptide	4
Modulation of Drug Resistance by Limonene: Inhibition of Efflux Pumps in Staphylococcus aureus Strains RN-4220 and IS-58	4
Glutamine Antagonist GA-607 Causes a Dramatic Accumulation of FGAR which can be used to Monitor Target Engagement	4
New Horizons in the Treatment of Neurological Disorders with Tailorable Gold Nanoparticles	4
Role of Natural Products in the Treatment of Obesity: Nanotechnological Perspectives	4
An Overview of the Neuropharmacological Potential of Thymoquinone and its Targeted Delivery Prospects for CNS Disorder	4
Targeting the Pathological Hallmarks of Alzheimer’s Disease Through Nanovesicleaided Drug Delivery Approach	4
Effect of Green Tea and (-)-Epigallocatechin Gallate on the Pharmacokinetics of Rosuvastatin	4
Gut Microbiota as the Potential Mechanism to Mediate Drug Metabolism Under High-altitude Hypoxia	4
In Silico ADMET Evaluation of Natural DPP-IV Inhibitors for Rational Drug Design against Diabetes	4
Drug-induced Bile Duct Injury - A Short Review	4
The Role of Biotransformation in the Activity of Endocrine Disruptors	4
The Current Application of LC-MS/MS in Pharmacokinetics of Traditional Chinese Medicines (Recent Three Years): A Systematic Review	4
Withania somnifera in Neurological Disorders: Ethnopharmacological Evidence, Mechanism of Action and its Progress in Delivery Systems	4
Annonaceae Family Alkaloids as Agents Against Leishmaniasis: A Review and Molecular Docking Evaluation	4
Regulatory Effects of N-3 PUFAs on Pancreatic β-cells and Insulin-sensitive Tissues	4
Suppression of Melanoma Growth in a Murine Tumour Model Using Orthosiphon stamineus Benth. Extract Loaded in Ethanolic Phospholipid Vesicles (Spherosome)	4
Current Advances in Drug Delivery Systems for Capsule Endoscopy	4
Clinical Impact of Co-medication of Levetiracetam and Clobazam with Proton Pump Inhibitors: A Drug Interaction Study	4
Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases & their Metabolic Profiling-Part 2	4
Chemistry and Antioxidant Potential of Phytoconstituents from Aegle Marmelos Fruit-Shell	4
JAK Inhibition as a Therapeutic Strategy for Inflammatory Bowel Disease	4
CYP2C and CYP2B Mediated Metabolic Activation of Retrorsine in Cyp3a Knockout Mice	4
Herb-Drug Interactions and Their Impact on Pharmacokinetics: An Update	4
Nanotechnology Driven Approaches for the Management of Parkinson’s Disease: Current Status and Future Perspectives	3
Lipid Nanoformulations in the Treatment of Neuropsychiatric Diseases: An Approach to Overcome the Blood Brain Barrier	3
Comparison between Atorvastatin and Rosuvastatin on Secondary Percutaneous Coronary Intervention Rate and the Risk Factors in Patients with Coronary Heart Disease	3
Orchestration of Obesolytic Activity of Microbiome: Metabiotics at Centre Stage	3
Dose Optimization of Gentamicin in Critically Ill Neonates	3
The Influences and Mechanisms of High-altitude Hypoxia Exposure on Drug Metabolism	3
Anticancer Activity and In Silico ADMET Properties of 2,4,5-Trisubstitutedthiazole Derivatives	3
In vitro Metabolism of Humantenine in Liver Microsomes from Human, Pig, Goat and Rat	3
Differential Impacts of Azole Antifungal Drugs on the Pharmacokinetic Profiles of Dasatinib in Rats by LC-MS-MS	3
Human Papillomavirus Induced Cervical and Oropharyngeal Cancers: From Mechanisms to Potential Immuno-therapeutic Strategies	3
Potential of Mirabegron and its Extended-release Formulations for the Treatment of Overactive Bladder Syndrome	3
A Comprehensive Review of the Pharmacologic Perspective on Loop Diuretic Drug Interactions with Therapeutically Used Drugs	3
Unveiling the Role of Cytochrome P450 (2E1) in Human Brain Specifically in Parkinson’s Disease - Literature Review	3
Impact of Pharmacogenetic Determinants of Tacrolimus and Mycophenolate on Adverse Events in Renal Transplant Patients	3
The Development of a Physiologically Based Pharmacokinetic (PBPK) Model of Andrographolide in Mice and Scaling it up to Rats, Dogs, and Humans	3
Pharmacokinetics and Efficacy of Ceftriaxone in Staphylococcal Mastitis in Crossbred Cows Following Single Intravenous Administration	3
Aceclofenac-Loaded Microspheres Prepared by Vesicular Ionotropic Gelation to Minimize Drug-induced Gastric Ulcers in Rats	3
Detection and Identification of Catalpol Metabolites in the Rat Plasma, Urine and Faeces Using Ultra-high Performance Liquid Chromatography-Q Exactive Hybrid Quadrupole-orbitrap High-resolution Accura	3
Effects of Astragaloside IV on the Pharmacokinetics of Metoprolol in Rats and its Mechanism	3
In Silico Pharmacokinetic Study of Vancomycin Using PBPK Modeling and Therapeutic Drug Monitoring	3

Pharmacokinetics and Metabolism of Traditional Chinese Medicine in the Treatment of COVID-19	3
In Silico Meets In Vitro Techniques in ADMET Profiling of Drug Discovery (Part I)	3
Circadian Timekeeping in Anticancer Therapeutics: An Emerging Vista of Chronopharmacology Research	3
Pharmacokinetics-based Chronotherapy	3
Updates on the Pharmacology of Chloroquine against Coronavirus Disease 2019 (COVID-19): A Perspective on its Use in the General and Geriatric Population	3
Simultaneous Determination of Saponins and Lignans in Rat Plasma by UPLC- MS/MS and its Application to a Pharmacokinetic Study of Shenqi Jiangtang Granule	3
Pharmacokinetic Research Progress of Anti-tumor Drugs Targeting for Pulmonary Administration	3
Advances in Understanding the Metabolites and Metabolomics of Polygonum multiflorum Thunb: A Mini-review	3
Recent Progress on Mass Spectrum Based Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Traditional Chinese Medicine	3
Lipid carriers mediated targeted delivery of nutraceuticals: Challenges, role of blood brain barrier and promises of nanotechnology based ap-proaches in neuronal disorders.	3
Absorption, Disposition and Pharmacokinetic Properties of Novel Therapeutic Modalities	3
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China	3
Evaluating Lean Liver Volume as a Potential Scaler for In Vitro-In Vivo Extrapolation of Drug Clearance in Obesity Using the Model Drug Antipyrine	3
Pharmacokinetic Drug-Drug Interactions Involving Antiretroviral Agents: An Update	2
Changing Pain Management Strategy from Opioid-centric Towards Improve Postoperative Cognitive Dysfunction with Dexmedetomidine	2
Nucleic Acid Nanomaterials-based Therapy for Osteoarthritis: Progress and Prospects	2
Pharmacokinetics, Mass Balance, Tissue Distribution, and Metabolism of [3H]Catalpol in Rats: the Main Bioactive Component of Rehmannia glutinosa for the Treatment of Ischemic Stroke	2
Effects of Fasting andPhoenix dactyliferaon the Expression of Major Drug- Metabolizing Enzymes in the Mouse Livers	2
Pharmacokinetics and Tissue Distribution of Nasal Spray of a Novel Muscarinic Receptor Blocker, 101BHG-D01, in Dogs and Rats	2
Absorption, Disposition and Pharmacokinetic Properties of Novel Therapeutic Modalities (Part II)	2
How Antimalarials and Antineoplastic Drugs can Interact in Combination Therapies: A Perspective on the Role of PPT1 Enzyme	2
Identification and Quantification of MIDD0301 Metabolites	2
Covalent CES2 Inhibitors Protect against Reduced Formation of Intestinal Organoids by the Anticancer Drug Irinotecan	2
Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery	2
Effectiveness and Tolerability of Very-low Volume Preparation for Colonoscopy: A Narrative Review	2
Amino Acid and Biogenic Amine Adductions Derived from Reactive Metabolites	2
A HPLC-DAD-MS/MS Method for Simultaneous Determination of Six Active Ingredients of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in Rat Plasma and its Application to Pharmacokinetic	2
Integrated UPLC-MS/MS and UHPLC-Q-orbitrap HRMS Analysis to Reveal Pharmacokinetics and Metabolism of Five Terpenoids from Alpiniae oxyphyllae Fructus in Rats	2
A Randomized Trial of Short-term Treatment with Folic Acid to Reduce the Oxidative Stress of Patients with Chronic Kidney Disease	2
Nanotechnological Approaches for the Treatment of Triple-Negative Breast Cancer: A Comprehensive Review	2
Dermatokinetics: Advances and Experimental Models, Focus on Skin Metabolism	2
A Review On Huntington Protein: Insight Into Protein Aggregation and Therapeutic Interventions	2
New Psychoactive Substances, New Behaviours, New Drug-drug Interactions: Pharmacology of a Slam Session	2
Drug-gut Microbiome Interaction in Atherosclerosis Therapeutics	2
Evaluation of Dermorphin Metabolism Using Zebrafish Water Tank Model and Human Liver Microsomes	2
Physiologically Based Pharmacokinetic Model for Older Adults and Its Application in Geriatric Drug Research	2
Influence of Rifampicin Pre-treatment on the In vivo Pharmacokinetics of Metoclopramide in Pakistani Healthy Volunteers Following Concurrent Oral Administration	2
Absorption, Metabolism and Excretion of Surufatinib in Rats and Humans	2
Role of Drug-metabolizing Enzymes in Cancer and Cancer Therapy	2
Machine Learning in Drug Metabolism Study	2
miRNAs in SARS-CoV-2 Infection: An Update	2
Substrate-dependent Inhibition of Hypericin on Human Carboxylesterase 2: Implications for Herb-drug Combination	2
Insights into Potent Therapeutical Antileukemic Agent L-glutaminase Enzyme Under Solid-state Fermentation: A Review	2
Genetic Analysis of Pharmacogenomic VIP Variants of ABCB1, VDR and TPMT Genes in an Ethnically Isolated Population from the North Caucasus Living in Jordan	2
AOX1 and XDH Enzymes Genotyping and its Effect on Clinical Response to Azathioprine in Inflammatory Bowel Disease Patients Among Jordanian Population	2
Nanostructured Therapeutic Systems of PUFAs for the Treatment of Glioblastoma Multiforme	2
Impact of POR*28 Variant on Tacrolimus Pharmacokinetics in Kidney Transplant Patients with Different CYP3A5 Genotypes	2
Effect of Atorvastatin on Single Oral Pharmacokinetics and Safety of Daclatasvir in Rats: Emphasis on P-glycoprotein and Cytochrome P450	2
Surface Engineered Dendrimers: A Potential Nanocarrier for the Effective Management of Glioblastoma Multiforme	2
High-throughput LC-MS/MS Method for Simultaneous Determination of Pantoprazole and Atorvastatin in Rat Plasma: Application to a Pharmacokinetic Interaction Study	2
Stability of Ketoprofen Methylester in Plasma of Different Species	2
Vitamin D Metabolism Gene Polymorphisms and Their Associated Disorders: A Literature Review	2
Improved Therapeutic Efficacy of Topotecan Against A549 Lung Cancer Cells with Folate-targeted Topotecan Liposomes	2
A Systematic Review of Linezolid Pharmacokinetics/Pharmacodynamics in Patients Undergoing Continuous Renal Replacement Therapy: Does One Size Fit All?	2
Trends in Rationalized Brain Targeted Nanoparticles in Neurological Disorders (Part-III)	2
Different Effects of Polymorphic Flavin-Containing Monooxygenase 3 and Cytochrome P450 2A6 Activities on an Index of Arteriosclerosis as a Lifestyle-Related Disease in a General Population in Japan	2
Comprehensive Identification of Astilbin Metabolites in Rats Based on Multiple Metabolite Templates Combined with UHPLC-Q-Exactive Mass Spectrometry	2
Elevated Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Predict Drug-Induced Acute Kidney Injury	2
Effects of Montmorillonite on Growth Performance, Serum Biochemistry and Oxidative Stress of Red-Crowned Crane (Grus japonensis) Fed Mycotoxin-Contaminated Feed	1
Withdrawal Notice: Synergistic Effect of Myricetin and Phenolic Acid Derivatives on the Reversal of Dengue Fever Related Thrombocytopenia and its Pharmacokinetics study in Plasma by using HPLC and UPL	1
Different Inductive Effects of Praziquantel Racemate and its Enantiomers on the Enzyme CYP3A4 Mediated by Pregnane X Receptor and its Variants	1
Evaluation and Clinical Implication of Zhenwu Decoction on Seven Cytochrome P450 Enzyme in Chronic Heart Failure Rats	1
Meet Our Editor-in-Chief	1
Influence of SLCO1B1 Polymorphisms on the Pharmacokinetics of Mycophenolic Acid in Renal Transplant Recipients	1
The Promising Role of Natural Exosomal Nanoparticles in Cancer Chemoimmunotherapy	1
New Ultra Low Volume Bowel Preparation and Overview of Existing Bowel Preparations	1
Metabolism of Direct-acting Antiviral Agents (DAAs) in Hepatitis C Therapy: A Review of the Literature	1
Meropenem for the Pharmacological Treatment of Severe Infections in Critically Ill Pediatric Patients: Breakthrough Standard Treatment Strategies Based on PK/PD	1
Preclinical Pharmacokinetics and CYP Modulation Activity of Chebulinic Acid: A Potent Molecule Against Metabolic Disease	1
Phytofabricated Nanoparticle Formulation for Cancer Treatment: A Comprehensive Review	1
The Application of Nucleic Acid Nanomaterials in the Treatment of Mitochondrial Dysfunction	1
Comparison of the Inhibitory Effects of Clotrimazole and Ketoconazole against Human Carboxylesterase 2	1
Pharmacokinetics/Pharmacodynamics (PK/PD) of Ciprofloxacin in the Complicated Urinary Tract Infection (cUTI) Model in Diabetic Mice	1
A Randomized Study on the Bioequivalence of Desloratadine in Healthy Chinese Subjects and the Association of Different Metabolic Phenotypes With UGT2B10 and CYP2C8 Genotypes	1
A Mini-review on Recent Strategies and Applications of Nanomedicines to Combat Antimicrobial Resistance	1
Inhibition of Cytochrome P450 Enzyme and Drug-Drug Interaction Potential of Acid Reducing Agents Used in Management of CDK Inhibitors for Breast Cancer Chemotherapy	1
Characterization of Metabolites of α-mangostin in Bio-samples from SD Rats by UHPLC-Q-exactive Orbitrap MS	1
Biotransformation of Drugs and other Xenobiotics as Key Modulator of Toxicity	1
Framework Nucleic Acids: A Promising Vehicle for Small Molecular Cargos	1
Design and Evaluation of Sustained Release of Ornidazole by Dental Inserts	1
Design and Construction of Carboxylesterase 2c Gene Knockout Rats by CRISPR/Cas9	1
State-of-the-art Application of Artificial Intelligence to Transporter-centered Functional and Pharmaceutical Research	1
No Effect of PXR (8055C>T) Polymorphism on the Pharmacokinetic Profiles of Piperaquine in Healthy Chinese Subjects	1
Concomitant Drug Treatment and Elimination in the RCC-affected Kidneys: Can We Kill Two Birds with One Stone?	1
Evaluation of Alterations in DNA Methylation of CYP3A4 Gene Upstream Regulatory Elements in Gastric Cancer and in Response to Diazinon Treatment	1
New Therapeutic Molecules and their Metabolism in Gastroenterology	1
Clay-based Formulations for Bioavailability Enhancement of Poorly Water-soluble Drugs	1
Establishment of a High Content Image Platform to Measure NF-κB Nuclear Translocation in LPS-induced RAW264.7 Macrophages for Screening Anti-inflammatory Drug Candidates	1
Additive Manufacturing and Printing Approaches for the Development of Pharmaceutical Dosage Forms with Improved Biopharmaceutical Attributes	1
Rapid Profiling of the Marker Components in Artemisia annua L. and their Metabolites in Rats Using an Improved Liquid Chromatography-tandem Highresolution Mass Spectrometry-based Technology	1
Study on the Relationship between Rivaroxaban and Factor Xa Activity in Blood Based on HPLC-MS/MS	1
Synthesis and Biomedical Applications of DNA Hydrogel	1
The Emerging Roles of Extracellular Vesicles in Ovarian Cancer	1
Pharmacokinetic/Pharmacodynamic Study of Salt-Processed Product of Cuscutae Semen with Hepatoprotective Effects	1
UPLC-ESI-Q-TOF/MS Based Metabolic Profiling of Protosappanin B in Rat Plasma, Bile, Feces, Urine and Intestinal Bacteria Samples	1