OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Bioscience and Bioengineering is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Nitrogen removal and N2O emissions in anammox reactors: Influence of reactor design on process performance and microbial communities	68
Simultaneous production of cellobiose and xylobiose from alkali-treated bagasse using cellulase secreted by Fe-ion-irradiated Trichoderma reesei mutant	60
Developing a simple activity test to estimate nitrous oxide production from sewage treatment	58
Single-cell transcriptomic profiling of platelet-adherent circulating tumor cells using a microcavity-gel manipulation platform	55
Characterization of flavor quality in sago starch produced by different processing methods: Insights from physicochemical, metabolomic, and sensory analyses	39
Fermentation of rose residue by Lactiplantibacillus plantarum B7 and Bacillus subtilis natto promotes polyphenol content and beneficial bioactivity	31
Novel promoter of Pseudozyma antarctica exhibits stable glucose-mediated activation and copper-mediated suppression of flanking genes	31
Effects of genome instability of parental CHO cell clones on chromosome number distribution and recombinant protein production in parent-derived subclones	29
Blending of selected yeast extract and peptone for inducible and constitutive protein production in Escherichia coli using the pET system	29
Synergistic effect of glucagon-like peptide-1 analogue liraglutide and ZnO on the antibacterial, hemostatic, and wound healing properties of nanofibrous dressings	28
Three carbohydrate-binding modules of laminarinase LA-Lam recognize β-1,3-glucan and enhance hydrolytic activity	28
Effect of yeast chromosome II aneuploidy on malate production in sake brewing	28
Combined use of phosphorus containing calcium silicate and phosphate-solubilizing bacterium as a solid biofertilizer for sustainable soybean cultivation	27
Production and evaluation of enzyme-modified cheese adding protease or lipase to improve quality properties	26
Establishment of a novel cell line, CHO-MK, derived from Chinese hamster ovary tissues for biologics manufacturing	26
Effect of humic acid on aerobic denitrification by Achromobacter sp. strain GAD-3	25
Identification of tryptophanase from Escherichia coli for the synthesis of S-allyl-l-cysteine and related S-substituted cysteine derivatives	25
Whole-genome sequence and characterization of a marine red yeast, Rhodosporidium sphaerocarpum GDMCC 60679, featuring the assimilation of ammonia nitrogen	24
Preparation and performance of biocompatible gadolinium polymer as liver-targeting magnetic resonance imaging contrast agent	24
Succession of microbial community of the pit mud under the impact of Daqu of Nongxiang Baijiu	23
Catalytic potential of a fungal indole prenyltransferase toward β-carbolines, harmine and harman, and their prenylation effects on antibacterial activity	23
Drug in adhesive transdermal patch containing antibiotic-loaded solid lipid nanoparticles	22
Environmental factors drive microbial community succession in biofortified wheat Qu and its improvement on the quality of Chinese huangjiu	22
Effect of sodium metabisulfite treatment and storage condition on metabolic profile of young coconut (Cocos nucifera L.)	21
Longitudinal gut mycobiota changes in Japanese infants during first three years of life	21

Triacetic acid lactone production using 2-pyrone synthase expressing Yarrowia lipolytica via targeted gene deletion	21
Metagenomic profiling of antibiotic resistance genes and their associations with the bacterial community along the Kanda River, an urban river in Japan	21
Achyranthes bidentate extracts protect the IL-1β-induced osteoarthritis of SW1353 chondrocytes	21
Aspergillus oryzae strains heterogeneously produce plant polysaccharide degradation-related enzymes	20
Coculture model of a liver sinusoidal endothelial cell barrier and HepG2/C3a spheroids-on-chip in an advanced fluidic platform	20
Exosomes for hair growth and regeneration	20
Yeast diversity during the spontaneous fermentation of wine in a winery and in a laboratory using sterilized equipment	20
Insight investigation into the response pattern of microbial assembly succession and volatile profiles during the brewing of sauce-flavor baijiu based on bioaugmentation	19
Characterization of a molting-related chitinase from a land crab, Chiromantes haematocheir	19
Intraspecific comparison of mitochondrial genomes reveals the evolution in medicinal fungus Ganoderma lingzhi	19
Locus heterogeneity in the mechanism underlying the superior fermentation performances of phylogenetically distant sake yeasts	18
Application of peptide barcoding to obtain high-affinity anti-PD-1 nanobodies	17
Dual-color membrane-type immunoglobulin-directed hybridoma screening for selective and accelerated monoclonal antibody production	17
Microbial glycosylation of antitubercular agent chlorflavonin	17
High accumulation of the Man5GlcNAc2 structure by combining N-acetylglucosaminyltransferase I gene suppression and mannosidase I gene overexpression in Nicotiana tabacum SR1	17
Establishment of a nitrate-reductase promoter-driven inducible expression system for metabolic engineering in the marine diatom Fistulifera solaris	16
Development of a simple cultured cell–anaerobic microbial co-culture system using liquid paraffin	16
Current advancements in systems and synthetic biology studies of Saccharomyces cerevisiae	16
Optimization of heterologous protein production process using genetically engineered Ogataea minuta toward industrial-scale manufacturing	16
Mechanisms of production and control of acetate esters in yeasts	16
Galactosylation of cell-surface glycoprotein required for hyphal growth and cell wall integrity in Schizosaccharomyces japonicus	15
Genomic analysis of Paenibacillus macerans strain I6, which can effectively saccharify oil palm empty fruit bunches under nutrient-free conditions	15
Effects of vascular endothelial cells on the neurite outgrowth of nerve cells	15
Comparison of a new peak detection function for selecting a phase-appropriate multi-attribute method system	14
High productivity of cellulase and xylanase enzymes in the mycelial-dispersed Pleurotus ostreatus Δpkac2 strain	14
One-pot synthesis of fibrillar-shaped functional nanomaterial using microbial transglutaminase	14
The bio3 mutation in sake yeast leads to changes in organic acid profiles and ester levels but not ethanol production	14
Anti-microbial, anti-oxidant and wound healing capabilities of Aloe vera-incorporated hybrid nanoflowers	14
Generation of a plasmid series for rapid sub-cloning and use in various Enterobacteriaceae	13
Sequence features around cleavage sites are highly conserved among different species and a critical determinant for RNA cleavage position across eukaryotes	13
Functionalized peptide hydrogel to generate human insulin-producing cells in vitro	13
Characterization of the bacterial community structure in traditional Gifu ayu-narezushi (fermented sweetfish)	13
Effect of S-adenosyl-methionine accumulation on hineka odor in sake brewed with a non-Kyokai yeast	13
Biotransformation-guided purification of a novel glycoside derived from the extracts of Chinese herb Baizhi	13
Production of GABA-enriched tomato juice by Lactiplantibacillus plantarum KB1253	13
Characteristics of kopyor coconut (Cocos nucifera L.) using sensory analysis and metabolomics-based approach	13
Characterization of unique EDTA-insensitive methylthioalkylmalate synthase from Eutrema japonicum and its potential application in synthetic biology	13
Generation of novel respiratory syncytial virus vaccine candidate antigens that can induce high levels of prefusion-specific antibodies	13
Domain structure and function of α-1,3-glucanase Agl-EK14 from the gram-negative bacterium Flavobacterium sp. EK-14	12
Role of low-level alternating current and impedance for enhancing microalgae biomass and lipid production	12
Enhancing intracellular NADPH bioavailability through improving pentose phosphate pathway flux and its application in biocatalysis asymmetric reduction reaction	12
Combinational manipulation of transcription factors, CreA and ClbR, is a viable strategy to improve cellulolytic enzyme production in Aspergillus aculeatus	12
Bioinformatics in bioscience and bioengineering: Recent advances, applications, and perspectives	12
Near-infrared imaging-based high-content analysis for label-free assessment of internal cellular heterogeneity in spheroid	12
Peptide array screening with anti-GLP-1 monoclonal antibody: Discovery of cysteine-containing DPP-IV inhibitory peptides	11
Episomal maintenance of introduced plasmid with or without AMA1 sequence in the basidiomycete fungus Pleurotus ostreatus	11
Optimization of bacteriophage propagation in high-yield continuous culture (cellstat) meeting the constraints of industrial manufacturing processes	11
Isolation of arginine deiminase system-deficient mutants of Tetragenococcus halophilus using arginine analog canavanine	11
Control of carbon dioxide concentration in headspace of multiple flasks using both non-electric bellows pump and shaking incubator	11
Bacterial removal using liposomes and an anionic adsorber	11

Expansion of human mesenchymal stem cells on poly(vinyl alcohol) microcarriers	11
Isolation and characterization of koji mold (Aspergillus oryzae) from nature in Niigata	10
Isolation of aflatoxin biosynthetic inhibitor from Chondrostereum purpureum mushroom culture filtrate	10
Elucidation of d-allulose recognition mechanism in ketose 3-epimerase	10
Overexpression of the DHA1 family, ChlH and ChlK, leads to enhanced dicarboxylic acids production in koji fungi, Aspergillus luchuensis mut. kawachii and Aspergillus oryzae	10
Ribonucleoprotein-based CRISPR/Cas9 genome co-editing in Aspergillus luchuensis mut. kawachii	10
Highly genomic instability of super-polyploid strains of Saccharomyces cerevisiae	10
Spatial, temporal, and biotic changes in the natural abundances of stable carbon and nitrogen isotopes in a biological treatment reactor	10
Topical delivery of gel-in-oil emulsion cocktail with growth factors for the treatment of diabetic pressure ulcers	10
Reduction of the alcohol-stimulative taste of Japanese pot-distilled spirits	9
Enhancing synthesis of ethyl lactate in rice baijiu fermentation by adding recovered granular cells	9
Efficient yeast breeding using a sake metabolome analysis for a strain evaluation	9
Correction of substitution, deletion, and insertion mutations by 5′-tailed duplexes	9
Characterization of entrapment behavior of polyphenols in nanostructured lipid carriers and its effect on their antioxidative activity	9
Evaluation of cellular characteristics and genome editing responses in chicken primordial germ cell lines	9
In-situ collagen mineralization modulates metastatic properties of breast cancer cells	9
Functional analysis of a putative type III polyketide synthase from deep-sea sediment metagenome	9
Machine learning strategy to boost 1-deoxynojirimycin production through fermentation by Bacillus amyloliquefaciens	9
Role of bacterial community succession in flavor formation during Sichuan sun vinegar grain (Cupei) fermentation	9
Cell-penetrating activity of a short-chain ε-poly-l-α-lysine	9
Recent advances in plant-based bioproduction	9
Efficient production and characterization of soluble active human β-1,2-N-acetylglucosaminyltransferase II in bacteria	8
Constitutive and inducer-free production of xanthine oxidase in a Pseudomonas putida cell factory	8
Early-stage transplant responses in miniature-liver implants based on decellularization-recellularization technology	8
Acetic acid-induced translational repression involves eIF2B body formation and Ded1 sequestration into stress granules in yeast	8
Metabolomics-based investigation of the differences between traditional and modern soy sauce	8
Controlling the carbon flux between glycolysis and the pentose phosphate pathway via targeted protein degradation in Corynebacterium glutamicum	8
Biomimetic conjugation inspired from pheomelanin via thiol–quinone addition for enzymatic functionalization of fibroin	8
Modeling the sake brewing characteristics of rice from brown rice metabolites	8
Identification and characterization of rabbit scFv antibodies suitable for immuno-affinity separation of recombinant human kynureninase from Escherichia coli cell lysate	8
Role of the CYR1G2066A mutation in ethanol tolerance of sake yeast Kyokai no. 11	8
Preferential correction of target genes by 5′-tailed duplexes with an antisense editor strand	8
Characterization and application of Lachancea thermotolerans isolates for sake brewing	8
Beneficial effect of optimizing the expression balance of the mevalonate pathway introduced into the mitochondria on terpenoid production in Saccharomyces cerevisiae	8
Optimizing in vitro expression balance of central dogma-related genes using parallel reaction monitoring	8
Analysis of nitrogen source assimilation in industrial strains of Aspergillus oryzae	7
Enhancing sensory quality of heat-not-burn tobacco via bioaugmentation with Cytobacillus oceanisediminis C4 and amylase	7
Different traits for cold tolerance of extremely thermophilic Calditerricola strains isolated from mesothermal municipal sewage sludge and its hyperthermal compost	7
Superior high-efficiency and high-throughput volatile flavor extraction of Japanese fermented seasonings by solvent-assisted stir bar solid extraction with reverse extraction	7
Wide distribution of extracellular electron transfer functionality in natural proteinaceous organic materials for microbial reductive dehalogenation	7
Gene identification and enzymatic characterization of the initial enzyme in pyrimidine oxidative metabolism, uracil-thymine dehydrogenase	7
Selective and high-yield production of ethyl α-d-glucopyranoside by the α-glucosyl transfer enzyme of Xanthomonas campestris WU-9701 and glucose isomerase	7
Hydrogen-producing conditions and mutation mechanisms of a highly efficient mutant strain Ethanoligenens harbinense YR-3	7
Ergothioneine production by Corynebacterium glutamicum harboring heterologous biosynthesis pathways	7
Expression of His-tagged NADPH-dependent acetoacetyl-CoA reductase in recombinant Escherichia coli BL-21(DE3)	7
Corrigendum to “Early detection of leptospirosis using Anti-LipL32 carbon nanotube immunofluorescence probe” [J. Biosci. Bioeng. 130 (4) (2020) 424–430]	7
Key media microsupplements for boosting de novo lipogenesis in an oleaginic yeast isolate	7
Silica adsorption tag derived from the silica polycondensation protein glassin for the immobilization of soluble proteins	7
Expression of heterochromatin protein 1 affects citric acid production in Aspergillus luchuensis mut. kawachii	7
Recent advances in single-cell RNA sequencing of bacteria: Techniques, challenges, and applications	7
Prediction of antibody production performance change in Chinese hamster ovary cells using morphological profiling	7
Whole-genome draft assemblies of Paracoccus pantotrophus DSM 11073 and Paracoccus sp. AS002: Phylogenetics entails classification as Paracoccus versutus AS002	7
Biochemical characterization of l-asparagine synthetase from Streptococcus thermophilus and its application in the enzymatic synthesis of β-aspartyl compounds	7
Microwave pretreatment of glycogen-containing cyanobacteria Synechococcus elongatus UTEX 2973 to enhance enzymatic saccharification and fermentation for bioethanol production	7
Zein/Fucoidan microcarriers promote myogenic differentiation via topographical cues and hydrodynamic modulation	7
Optimization of tyrosol-producing pathway with tyrosine decarboxylase and tyramine oxidase in high-tyrosine-producing Escherichia coli	7
Expansion of omega-3 polyunsaturated fatty acid metabolism of the oleaginous diatom Fistulifera solaris by genetic engineering	7
Solid-state fermentation of corn gluten meal with Aspergillus oryzae 6002 enhances amino acid and dipeptide accumulation while retaining high protein content	7
Semi-wet methanogen cathode composed of oak white charcoal for developing sustainable microbial fuel cells	7