OOIR: Observatory of International Research

Papers

(The TQCC of Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Functionally diverse front-end desaturases are widespread in the phylum Annelida	68
Eicosapentaenoic acid inhibits cholesterol efflux pathways from cholesterol-loaded human THP-1 macrophages by reducing the hydrolysis of cholesteryl esters mediated by carboxylesterase 1	59
Phospholipid isotope tracing suggests β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma	30
Transcriptome profiling of differentiating adipose-derived stem cells across species reveals new genes regulating adipogenesis	30
Co-existence of type I fatty acid synthase and polyketide synthase metabolons in Aurantiochytrium SW1 and their implications for lipid biosynthesis	28
Proteomic and lipidomic landscape of the infrapatellar fat pad and its clinical significance in knee osteoarthritis	24
Targeting peroxisomal fatty acid β-oxidation lowers fasting glucose by suppressing gluconeogenesis	22
Hippo pathway activation causes multiple lipid derangements in a murine model of cardiomyopathy	20
From worms to humans: Understanding intestinal lipid metabolism via model organisms	20
Modulation of lipid droplet biogenesis by p38 MAPK and caspase-1 in docosahexaenoic acid-induced EA.hy926 endothelial cell apoptosis	19
The PAH1-encoded phosphatidate phosphatase of Yarrowia lipolytica differentially affects gene expression and lipid biosynthesis	18
Eicosanoid biosynthesizing enzymes in Prototheria	18
Effect of α-ketoglutarate on maternal lipid homeostasis and mitochondrial status perturbed by gestational arsenic exposure	17
Editorial Board	16
Editorial Board	16
Dysregulation of lipid metabolism in the liver of Tspo knockout mice	16
Molecular mechanisms of cytochrome P450-derived epoxy-fatty acids neuroprotection	16
Nuclear phosphoinositides: An exploration into their regulation, roles and physico-chemical environment	15
Calpain-1 is required for abnormality of liver function and metabolism in apolipoprotein E knockout mouse evaluated noninvasively by small animal MRI and PET-CT	15
MiR-424-3p suppresses adipogenesis via HNRNPA0 targeting and p53-mediated ferroptosis	15
Role of sphingolipids in the host-pathogen interaction	14
Luteolin, as a bidirectional ROS regulator, elevates mouse beige adipocyte browning	14
Mechanism of preventive effects of exendin-4 and des-fluoro-sitagliptin in a murine model of fructose-induced prediabetes	14
1-Methylnicotinamide promotes hepatic steatosis in mice: A potential mechanism in chronic alcohol-induced fatty liver disease	13
Discovery of novel diagnostic biomarkers for Sjögren-Larsson syndrome by untargeted lipidomics	13

Comprehensive analysis of the composition of the major phospholipids during the asexual life cycle of the filamentous fungus Aspergillus nidulans	12
Lipid metabolism associated PLPP4 gene drives oncogenic and adipogenic potential in breast cancer cells	12
Increased obesogenic action of palmitic acid during early stage of adipogenesis	12
HSF4 promotes lipid peroxidation by transcriptionally regulating ALOX15 during lens terminal differentiation	12
Liposome of Phlorizin promote the repair of carotid atherosclerosis in rats by regulating inflammation and the Nrf2 signaling pathway	12
Sphinganine-induced lysosomal membrane permeabilization: Interplay with subcellular oxidative levels	12
Control of ALOX5 expression in monocytic cells using a synthetic riboswitch	12
The Sphinx and the egg: Evolutionary enigmas of the (glyco)sphingolipid biosynthetic pathway	11
Nuclear and chromatin rearrangement associate to epigenome and gene expression changes in a model of in vitro adipogenesis and hypertrophy	11
The protective role of peroxisome proliferator-activated receptor gamma in lipotoxic podocytes	11
The influence of IMPDH activity on ciliogenesis and adipogenesis of 3T3-L1 cells while undergoing differentiation	11
Lipids uniquely alter rates of insulin aggregation and lower toxicity of amyloid aggregates	11
Impact of sphingolipids on protein membrane trafficking	11
Phosphoinositide acyl chain diversity: comparative analysis across species and mouse tissues	10
FTO mediates m6A demethylation of HNF1A and drives hepatic steatosis in metabolic dysfunction-associated steatotic liver disease	10
The intestine-specific homeobox (ISX) modulates β-carotene-dependent regulation of microsomal triglyceride transfer protein (MTP) in a tissue-specific manner	10
A methionine-choline-deficient diet induces nonalcoholic steatohepatitis and alters the lipidome, metabolome, and gut microbiome profile in the C57BL/6J mouse	10
Hyperoxic recovery impacts on metabolic adaptations induced by hypoxic exercise: A lipidomics approach	10
Functional analysis and regulation mechanism of FGF19 on lipid metabolism in liver of large yellow croaker (Larimichthys crocea)	10
Maternal vitamin A deficiency programs offspring visceral hypersensitivity through RARβ-COX-2/PGE2 signaling	10
Distinct regions of Praja-1 E3 ubiquitin-protein ligase selectively bind to docosahexaenoic acid-containing phosphatidic acid and diacylglycerol kinase δ	10
Advances in lipid research: From bench to bedside	10
Type I collagen reduces lipid accumulation during adipogenesis of preadipocytes 3T3-L1 via the YAP-mTOR-autophagy axis	9
Cytoskeleton regulates lipid droplet fusion and lipid storage by controlling lipid droplet movement	9
Recent advances on the physiological and pathophysiological roles of polyunsaturated fatty acids and their biosynthetic pathway	9
Age-related changes in cardiolipin profile and functional consequences of altered fatty acid supply	9
Acute joint inflammation induces a sharp increase in the number of synovial fluid EVs and modifies their phospholipid profile	9
Cathepsin G-induced malignant progression of MCF-7 cells involves suppression of PAF signaling through induced expression of PAFAH1B2	9
LIMP-2 deficiency-associated glycolipid abnormalities in mice	9
Phosphatidylethanolamine species with n-3 and n-6 fatty acids modulate macrophage lipidome and attenuate responses to LPS stimulation	9
Dissection of the synthesis of polyunsaturated fatty acids in nematodes and Collembola of the soil fauna	9
Chlorogenic acid enhances PPARγ-mediated lipogenesis through preventing Lipin 1 nuclear translocation in Staphylococcus aureus-exposed bovine mammary epithelial cells	9
Regulation of macroautophagy and microautophagic lipophagy by phosphatidylserine synthase Cho1 and external ethanolamine	9
Aerobic exercise-induced decrease of chemerin improved glucose and lipid metabolism and fatty liver of diabetes mice through key metabolism enzymes and proteins	9
Acteoside improves adipocyte browning by CDK6-mediated mTORC1-TFEB pathway	8
Phosphoinositide and redox dysregulation by the anticancer methylthioadenosine phosphorylase transition state inhibitor	8
Liver X receptor activation mitigates oxysterol-induced dysfunction in fetoplacental endothelial cells	8
The impact of fasting on adipose tissue metabolism	8
Editorial Board	8
Study on the response of Punicalagin to AGEs — Induced inflammation based on lipidomics	8
The effect of perinatal supplementation of DHA on specialized pro-resolving lipid mediators in the brain of offspring	8
Editorial Board	8
Vitamin D status alters genes involved in ovarian steroidogenesis in muskrat granulosa cells	8
Origin and evolution of yeast carotenoid pathways	8
Editorial Board	8
Editorial Board	8
TMAO induces pyroptosis of vascular endothelial cells and atherosclerosis in ApoE−/− mice via MBOAT2-mediated endoplasmic reticulum stress	8
Effect of N-glycosylation on secretion, degradation and lipoprotein distribution of human serum amyloid A4	8
Abnormal expression of sphingolipid-metabolizing enzymes in the heart of spontaneously hypertensive rat models	8
Corrigendum to “Inducible beige adipocytes improve impaired glucose metabolism in interscapular BAT-removal mice” [Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1866 (2021) 158871]	8

Hypertriglyceridemia impairs HDL functionality, promotes macrophage metabolic activation and exacerbates antigen-induced rheumatoid arthritis in mice which can be reversed by fenofibrate treatment	8
Oroxylin A ameliorates non-alcoholic fatty liver disease by modulating oxidative stress and ferroptosis through the Nrf2 pathway	8
Glucagon-like peptide-2 mobilization of intestinal lipid does not require canonical enterocyte chylomicron synthetic machinery	7
Pulmonary surfactant protein SP-C regulates lipid vesicle uptake by alveolar type II cells and macrophages: Role of lipids, palmitoylation, and environment	7
Echinacoside suppresses macrophage lipid accumulation and attenuates atherosclerosis via the MDM2/PPARγ/ABCA1 signaling axis	7
Sex modulates the diet-induced changes to the plasma lipidome in a rat model of cardiorespiratory fitness	7
Single-cell RNA and ATAC sequencing reveals cell subsets characteristics in adipose-derived stem cells	7
Different effects of Lorenzo's oil components against very long-chain fatty acid-induced endoplasmic reticulum stress in peroxisome-deficient CHO cells	7
Recent advances in carotenoid absorption, distribution, and elimination	7
How the liver transcriptome and lipid composition influence the progression of nonalcoholic fatty liver disease to hepatocellular carcinoma in a murine model	7
Futile cycle of β-oxidation and de novo lipogenesis are associated with essential fatty acids depletion in lipoatrophy	7
GM1 oligosaccharide efficacy against α-synuclein aggregation and toxicity in vitro	7
Subcellular Cartography of the Phosphoinositide Multiverse	7
Loss of the acyltransferase TMEM68 leads to growth delay and dysregulation of triacylglycerol and glycerophospholipid homeostasis in the mouse brain	7
Generation and characterization of a mouse model for bile salt export pump deficiency with the p.E297G mutation	7
Zebrafish as outgroup model to study evolution of scavenger receptor class B type I functions	7
Altered levels of sphingomyelins, ceramides, glycerophospholipids, and diacylglycerols in thymoma tissues	7
Editorial Board	7
Valproate causes inositol depletion in yeast by decreasing levels of phosphatidic acid and increasing Opi1-mediated repression of INO1 expression	7
Adcy8 deficiency contributes to impaired lipolysis and an increased prevalence of obesity in mice	7
Silencing ANGPTL8 reduces mouse preadipocyte differentiation and insulin signaling	6
Cold-induced phosphatidylethanolamine synthesis in liver and brown adipose tissue of mice	6
Caveolin-2 knockout suppresses the formation and progression of oral leukoplakia via lipid metabolism disruption	6
Characterization of lipid signatures in the plasma and insulin-sensitive tissues of the C57BL/6J mice fed on obesogenic diets	6
Cold-sensitive pathway elongates a non-native cis-7-hexadecenoic acid to cis-9-octadecenoic acid in the cyanobacterium Synechocystis sp. PCC 6803	6
Endogenous synthesis of n−3 PUFAs can reduce lipid synthesis in Fad3 transgenic cattle	6
trans-Cinnamic acid alleviates high-fat diet induced hepatic steatosis by activating AMPK-mTOR pathway	6
Substituents of the polysaccharide region of LPS in Legionella pneumophila sg1 modulate interactions with host cells	6
PNPLA-mediated lipid hydrolysis and transacylation – At the intersection of catabolism and anabolism	6
Surfactant nebulization in severe COVID-19: Tracheal aspirate phospholipid turnover and metabolism	6
Architecture and function of yeast phosphatidate phosphatase Pah1 domains/regions	6
Arabidopsis AtCYP71B23: Detection of non-CYP74 enzyme of oxylipin biosynthesis	6
SCD1 is nutritionally and spatially regulated in the intestine and influences systemic postprandial lipid homeostasis and gut-liver crosstalk	6
Induction of lipid autophagy by chitosan-coated selenium nanoparticles mitigates NAFLD in vitro and in vivo	6
Linarin alleviates high-fat diet-induced NAFLD via modulating the PI3K/Akt/mTOR pathway, autophagy, and gut microbiota	6
OTUD7B controls oxLDL uptake by stabilizing Lox-1 in THP-1 and U937 cells	6
From LAL-D to MASLD: Insights into the role of LAL and Kupffer cells in liver inflammation and lipid metabolism	6
Lipid droplet isolation as a novel platform for spectroscopic investigation of cargo modifications	6
Palmitoylation of C4BPA in porcine epididymosomes mitigates complement C4-mediated damage to sperm	6