OOIR: Observatory of International Research

Papers

(The TQCC of Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Health benefits of fucoxanthin in the prevention of chronic diseases	89
Cholesterol, lipoproteins, and COVID-19: Basic concepts and clinical applications	72
Carotenoids and their role in cancer prevention	71
The macular carotenoids: A biochemical overview	69
Insights into VPS13 properties and function reveal a new mechanism of eukaryotic lipid transport	64
Carotenoid research: History and new perspectives for chemistry in biological systems	57
Carotenoid metabolism at the intestinal barrier	49
Effects of short chain fatty acids on metabolic and inflammatory processes in human health	47
Carotenoid biofortification in crop plants: citius, altius, fortius	44
Direct and indirect cholesterol effects on membrane proteins with special focus on potassium channels	42
Ketone metabolism in the failing heart	42
Novel signaling aspects of ceramide 1-phosphate	42
Atg2 and Atg9: Intermembrane and interleaflet lipid transporters driving autophagy	40
The HDL Proteome Watch: Compilation of studies leads to new insights on HDL function	40
Carotenoids and carotenoid conversion products in adipose tissue biology and obesity: Pre-clinical and human studies	40
The role of β-carotene and vitamin A in atherogenesis: Evidences from preclinical and clinical studies	39
Role of lipids in pathophysiology, diagnosis and therapy of hepatocellular carcinoma	37
Retinoids in health and disease: A role for hepatic stellate cells in affecting retinoid levels	36
Carotenoids and fatty liver disease: Current knowledge and research gaps	34
Lipidomic characterization of exosomes isolated from human plasma using various mass spectrometry techniques	31
Comparative anti-inflammatory effects of plant- and marine-derived omega-3 fatty acids explored in an endothelial cell line	30
Mechanistic understanding of β-cryptoxanthin and lycopene in cancer prevention in animal models	29
Lipidomics of brown and white adipose tissue: Implications for energy metabolism	29
Systems biology approaches to study lipidomes in health and disease	28
Lipid droplets in prostate cancer cells and effect of irradiation studied by Raman microspectroscopy	28

Stearoyl-CoA desaturase 5 (SCD5), a Δ-9 fatty acyl desaturase in search of a function	28
Fargesin alleviates atherosclerosis by promoting reverse cholesterol transport and reducing inflammatory response	26
Structural and mechanistic aspects of carotenoid cleavage dioxygenases (CCDs)	26
Salvianolic acid B ameliorates atherosclerosis via inhibiting YAP/TAZ/JNK signaling pathway in endothelial cells and pericytes	26
The molecular aspects of absorption and metabolism of carotenoids and retinoids in vertebrates	26
Carotenoids in human skin	25
Sex-specific responses in placental fatty acid oxidation, esterification and transfer capacity to maternal obesity	25
Leading the way in the nervous system: Lipid Droplets as new players in health and disease	23
Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling	22
Role of the autotaxin–lysophosphatidate axis in the development of resistance to cancer therapy	22
Rab7 controls lipid droplet-phagosome association during mycobacterial infection	22
Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells	22
Alterations of brain endocannabinoidome signaling in germ-free mice	22
Membrane cholesterol regulates endocytosis and trafficking of the serotonin1A receptor: Insights from acute cholesterol depletion	22
Substantial PCSK9 inactivation in β-cells does not modify glucose homeostasis or insulin secretion in mice	22
Lysophosphatidylcholines inhibit human eosinophil activation and suppress eosinophil migration in vivo	21
Phosphate starvation causes different stress responses in the lipid metabolism of tomato leaves and roots	21
Long-term stimulation of toll-like receptor-2 and -4 upregulates 5-LO and 15-LO-2 expression thereby inducing a lipid mediator shift in human monocyte-derived macrophages	21
“Spexin improves adipose tissue inflammation and macrophage recruitment in obese mice”	21
Insulin receptor deficiency reduces lipid synthesis and reproductive function in the insect Rhodnius prolixus	20
Sterols as dietary markers for Drosophila melanogaster	20
Enzymology of vertebrate carotenoid oxygenases	20
Production of branched-chain very-long-chain fatty acids by fatty acid elongases and their tissue distribution in mammals	20
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis	20
Regulation of lipid droplet homeostasis by hypoxia inducible lipid droplet associated HILPDA	19
HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease – Insights from randomized clinical trials and human genetics	19
Skin of atopic dermatitis patients shows disturbed β-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition	19
S1P and plasmalogen derived fatty aldehydes in cellular signaling and functions	19
Rab18 binds PLIN2 and ACSL3 to mediate lipid droplet dynamics	18
Empagliflozin ameliorates type 2 diabetes mellitus-related diabetic nephropathy via altering the gut microbiota	18
Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP	18
FAHFA footprint in the visceral fat of mice across their lifespan	18
The role of the C-terminal domain of PCSK9 and SEC24 isoforms in PCSK9 secretion	18
Evolutionary aspects and enzymology of metazoan carotenoid cleavage oxygenases	17
CD38 downregulation modulates NAD+ and NADP(H) levels in thermogenic adipose tissues	17
Inhibitory efficacy of lutein on adipogenesis is associated with blockage of early phase regulators of adipocyte differentiation	17
Amyloid beta increases ABCA1 and HMGCR protein expression, and cholesterol synthesis and accumulation in mice neurons and astrocytes	17
Hepatic and circulating levels of PCSK9 in morbidly obese patients: Relation with severity of liver steatosis	17
Lipid profiles of autophagic structures isolated from wild type and Atg2 mutant Drosophila	17
Lipidomic profiling of plasma free fatty acids in type-1 diabetes highlights specific changes in lipid metabolism	17
Lipids uniquely alter rates of insulin aggregation and lower toxicity of amyloid aggregates	17
Anti-inflammatory and anti-viral actions of anionic pulmonary surfactant phospholipids	16
Roles for lysophosphatidic acid signaling in vascular development and disease	16
Mammalian ABCG-transporters, sterols and lipids: To bind perchance to transport?	16
Bioactive lipids in inflammatory bowel diseases – From pathophysiological alterations to therapeutic opportunities	16
4-Hydroxynonenal induces Cx46 hemichannel inhibition through its carbonylation	15
Lipid metabolism and identification of biomarkers in asthma by lipidomic analysis	15
The key to the allergenicity of lipid transfer protein (LTP) ligands: A structural characterization	15
Regulation of adiponectin on lipid metabolism in large yellow croaker (Larimichthys crocea)	15
Curcumin stimulates exosome/microvesicle release in an in vitro model of intracellular lipid accumulation by increasing ceramide synthesis	15

The Drosophila model to interrogate triacylglycerol biology	15
GRAMD1-mediated accessible cholesterol sensing and transport	14
The “discovery” of lipid droplets: A brief history of organelles hidden in plain sight	14
β-carotene improves fecal dysbiosis and intestinal dysfunctions in a mouse model of vitamin A deficiency	14
High-density lipoproteins (HDL): Novel function and therapeutic applications	14
Sphingolipidomics of drug resistant Candida auris clinical isolates reveal distinct sphingolipid species signatures	14
The mitochondrial PKCδ/retinol signal complex exerts real-time control on energy homeostasis	14
Myoglobin, expressed in brown adipose tissue of mice, regulates the content and activity of mitochondria and lipid droplets	14
Interplay between β-carotene and lipoprotein metabolism at the maternal-fetal barrier	14
The roles of autotaxin/lysophosphatidic acid in immune regulation and asthma	14
Role of carotenoids and retinoids during heart development	14
Nanoscale mapping of nuclear phosphatidylinositol phosphate landscape by dual-color dSTORM	13
Mitigation of renal inflammation and endoplasmic reticulum stress by vildagliptin and statins in high-fat high-fructose diet-induced insulin resistance and renal injury in rats	13
Crosstalk between sterol and neutral lipid metabolism in the alga Haematococcus pluvialis exposed to light stress	13
Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis	13
The C. elegans PAQR-2 and IGLR-2 membrane homeostasis proteins are uniquely essential for tolerating dietary saturated fats	13
An altered lipid metabolism characterizes Charcot-Marie-Tooth type 2B peripheral neuropathy	13
Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice	13
12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats	13
Cellular cholesterol and how to find it	13
Courier service for phosphatidylinositol: PITPs deliver on demand	13
Angiopoietin-like protein 3, an emerging cardiometabolic therapy target with systemic and cell-autonomous functions	13
Lipolysis and lipophagy play individual and interactive roles in regulating triacylglycerol and cholesterol homeostasis and mitochondrial form in zebrafish	12
Apolipoprotein E isoform-dependent effects on the processing of Alzheimer's amyloid-β	12
Short-chain fatty acid mitigates adenine-induced chronic kidney disease via FFA2 and FFA3 pathways	12
Lipidomic analysis of epithelial corneal cells following hyperosmolarity and benzalkonium chloride exposure: New insights in dry eye disease	12
Long non-coding RNA PCA3 inhibits lipid accumulation and atherosclerosis through the miR-140-5p/RFX7/ABCA1 axis	12
Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol	12
Increased plasma levels of palmitoleic acid may contribute to beneficial effects of Krill oil on glucose homeostasis in dietary obese mice	12
Polyunsaturated fatty acids, specialized pro-resolving mediators, and targeting inflammation resolution in the age of precision nutrition	12
Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty acids	12
Impact of tetrahydrocannabinol on the endocannabinoid 2-arachidonoylglycerol metabolism: ABHD6 and ABHD12 as novel players in human placenta	12
The impact of fasting on adipose tissue metabolism	11
Emerging role of HDL in brain cholesterol metabolism and neurodegenerative disorders	11
Each phospholipase A2 type exhibits distinct selectivity toward sn-1 ester, alkyl ether, and vinyl ether phospholipids	11
Lysobisphosphatidic acid (LBPA) enrichment promotes cholesterol egress via exosomes in Niemann Pick type C1 deficient cells	11
Vps39 is required for ethanolamine-stimulated elevation in mitochondrial phosphatidylethanolamine	11
High-density lipoproteins: A promising tool against cancer	11
Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature	11
Inhibitory effects of ceramide kinase on Rac1 activation, lamellipodium formation, cell migration, and metastasis of A549 lung cancer cells	11
Inhibition of class I HDACs imprints adipogenesis toward oxidative and brown-like phenotype	11
Contribution of FP receptors in M1 macrophage polarization via IL-10-regulated nuclear translocation of NF-κB p65	11
Human adipocyte differentiation and composition of disease-relevant lipids are regulated by miR-221-3p	11
Effect of liver total sphingomyelin synthase deficiency on plasma lipid metabolism	11
Myocardin suppression increases lipid retention and atherosclerosis via downregulation of ABCA1 in vascular smooth muscle cells	10
Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats	10
Potential role of aryl hydrocarbon receptor signaling in childhood obesity	10
Sphingolipidomics of serum in extremely preterm infants: Association between low sphingosine-1-phosphate levels and severe retinopathy of prematurity	10
Loss and gain of function of Grp75 or mitofusin 2 distinctly alter cholesterol metabolism, but all promote triglyceride accumulation in hepatocytes	10
Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota	10
The lipid composition of yeast cells modulates the response to iron deficiency	10
The E3 ubiquitin ligase MARCHF6 as a metabolic integrator in cholesterol synthesis and beyond	10
Inhibition of alcohol-induced inflammation and oxidative stress by astaxanthin is mediated by its opposite actions in the regulation of sirtuin 1 and histone deacetylase 4 in macrophages	10
GDF11 rapidly increases lipid accumulation in liver cancer cells through ALK5-dependent signaling	9
Integrating the contributions of mitochondrial oxidative metabolism to lipotoxicity and inflammation in NAFLD pathogenesis	9
Lipid scavenging macrophages and inflammation	9
Specificity of ABCA7-mediated cell lipid efflux	9
Mast cell and heparin promote adipogenesis in superficial fascia of rats	9
Epoxyalcohol synthase activity of the CYP74B enzymes of higher plants	9
Chronic systemic exposure to IL6 leads to deregulation of glycolysis and fat accumulation in the zebrafish liver	9
Promotion of plasmalogen biosynthesis reverse lipid changes in a Barth Syndrome cell model	9
Beneficial effects of eicosapentaenoic acid on the metabolic profile of obese female mice entails upregulation of HEPEs and increased abundance of enteric Akkermansia muciniphila	9
Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation	9
Post-translational modifications of S1PR1 and endothelial barrier regulation	9
Eosinophils synthesize trihydroxyoctadecenoic acids (TriHOMEs) via a 15-lipoxygenase dependent process	9
Lipid rafts as viral entry routes and immune platforms: A double-edged sword in SARS-CoV-2 infection?	9
LPIAT1/MBOAT7 contains a catalytic dyad transferring polyunsaturated fatty acids to lysophosphatidylinositol	9
Reconstituted HDL as a therapeutic delivery device	9
Regulation of macrophage functions by FABP-mediated inflammatory and metabolic pathways	9
Palmitate induces human glomerular mesangial cells fibrosis through CD36-mediated transient receptor potential canonical channel 6/nuclear factor of activated T cell 2 activation	9
Neurotensin up-regulation is associated with advanced fibrosis and hepatocellular carcinoma in patients with MAFLD	9
Proresolving lipid mediators and liver disease	9
Biological action of docosahexaenoic acid in a 3D tissue-engineered psoriatic skin model: Focus on the PPAR signaling pathway	9
DECR1 directly activates HSL to promote lipolysis in cervical cancer cells	9
Lipidomic and metabolomic analysis reveals changes in biochemical pathways for non-small cell lung cancer tissues	9
Olesoxime, a cholesterol-like neuroprotectant restrains synaptic vesicle exocytosis in the mice motor nerve terminals: Possible role of VDACs	9
Estimation of the content of lipids composing endothelial lipid droplets based on Raman imaging	9
PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity	9
Molecular and cellular insights into the role of SND1 in lipid metabolism	9