OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Clinical Virology is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19	742
Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past	648
Low performance of rapid antigen detection test as frontline testing for COVID-19 diagnosis	455
Prevalence and severity of corona virus disease 2019 (COVID-19): A systematic review and meta-analysis	440
Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan, China	410
Evaluation of rapid antigen test for detection of SARS-CoV-2 virus	379
Comparison of seven commercial RT-PCR diagnostic kits for COVID-19	362
SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients	285
Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome	283
Epidemiology and clinical features of COVID-19: A review of current literature	269
COVID-19 and telemedicine: Immediate action required for maintaining healthcare providers well-being	251
Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study	239
Evaluation of two automated and three rapid lateral flow immunoassays for the detection of anti-SARS-CoV-2 antibodies	224
Evaluation of the EUROIMMUN Anti-SARS-CoV-2 ELISA Assay for detection of IgA and IgG antibodies	212
Assessment of SARS-CoV-2 serological tests for the diagnosis of COVID-19 through the evaluation of three immunoassays: Two automated immunoassays (Euroimmun and Abbott) and one rapid lateral flow immu	196
Panbio antigen rapid test is reliable to diagnose SARS-CoV-2 infection in the first 7 days after the onset of symptoms	185
The clinical course and its correlated immune status in COVID-19 pneumonia	185
Performance of six SARS-CoV-2 immunoassays in comparison with microneutralisation	169
Urgent need of rapid tests for SARS CoV-2 antigen detection: Evaluation of the SD-Biosensor antigen test for SARS-CoV-2	164
Brief clinical evaluation of six high-throughput SARS-CoV-2 IgG antibody assays	161
Comparison of Cepheid Xpert Xpress and Abbott ID Now to Roche cobas for the Rapid Detection of SARS-CoV-2	154
Quantification of SARS-CoV-2 antibodies with eight commercially available immunoassays	136
Challenges in use of saliva for detection of SARS CoV-2 RNA in symptomatic outpatients	135
Gastrointestinal, hepatobiliary, and pancreatic manifestations of COVID-19	131
Epidemiological characteristics and clinical features of 32 critical and 67 noncritical cases of COVID-19 in Chengdu	126

Dynamic profile of RT-PCR findings from 301 COVID-19 patients in Wuhan, China: A descriptive study	126
Clinical characteristics and risk assessment of newborns born to mothers with COVID-19	125
Multi-center evaluation of cepheid xpert® xpress SARS-CoV-2 point-of-care test during the SARS-CoV-2 pandemic	123
Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: Results from a single Italian Centre study on tocilizumab versus standard of care	121
Comparison of four new commercial serologic assays for determination of SARS-CoV-2 IgG	115
Supportive Treatment with Tocilizumab for COVID-19: A Systematic Review	114
Prevalence, clinical characteristics, and outcomes of pediatric COVID-19: A systematic review and meta-analysis	109
Longitudinal follow-up of IgG anti-nucleocapsid antibodies in SARS-CoV-2 infected patients up to eight months after infection	107
Comparing the analytical performance of three SARS-CoV-2 molecular diagnostic assays	104
Predictive factors for disease progression in hospitalized patients with coronavirus disease 2019 in Wuhan, China	104
Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories	96
Combination of four clinical indicators predicts the severe/critical symptom of patients infected COVID-19	95
Evaluation of a novel multiplexed assay for determining IgG levels and functional activity to SARS-CoV-2	92
Evaluation of a SARS-CoV-2 rapid antigen test: Potential to help reduce community spread?	91
Clinical characteristics of 225 patients with COVID-19 in a tertiary Hospital near Wuhan, China	90
Self-collection: An appropriate alternative during the SARS-CoV-2 pandemic	89
Characterisation of COVID-19 Pandemic in Paediatric Age Group: A Systematic Review and Meta-Analysis	88
Evaluation of rapid diagnosis of novel coronavirus disease (COVID-19) using loop-mediated isothermal amplification	88
Performance of the rapid high-throughput automated electrochemiluminescence immunoassay targeting total antibodies to the SARS-CoV-2 spike protein receptor binding domain in comparison to the neutrali	87
Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China	86
Clinical evaluation of an immunochromatographic IgM/IgG antibody assay and chest computed tomography for the diagnosis of COVID-19	85
Evidence and possible mechanisms of rare maternal-fetal transmission of SARS-CoV-2	85
Analytical sensitivity and clinical sensitivity of the three rapid antigen detection kits for detection of SARS-CoV-2 virus	84
Significant impact of nationwide SARS-CoV-2 lockdown measures on the circulation of other respiratory virus infections in Austria	83
High-Throughput Transcription-mediated amplification on the Hologic Panther is a highly sensitive method of detection for SARS-CoV-2	82
SARS-CoV-2 detection by direct rRT-PCR without RNA extraction	81
Multi-Stage Group Testing Improves Efficiency of Large-Scale COVID-19 Screening	79
SARS-CoV-2 exhibits intra-host genomic plasticity and low-frequency polymorphic quasispecies	78
Evaluation of the COVID19 ID NOW EUA assay	78
Performance evaluation of Abbott ARCHITECT SARS-CoV-2 IgG immunoassay in comparison with indirect immunofluorescence and virus microneutralization test	77
Comparison of the diagnostic sensitivity of SARS-CoV-2 nucleoprotein and glycoprotein-based antibody tests	71
A combined oropharyngeal/nares swab is a suitable alternative to nasopharyngeal swabs for the detection of SARS-CoV-2	70
Longitudinal characterization of the IgM and IgG humoral response in symptomatic COVID-19 patients using the Abbott Architect	70
Identification of multiple large deletions in ORF7a resulting in in-frame gene fusions in clinical SARS-CoV-2 isolates	69
Comparison of commercial realtime reverse transcription PCR assays for the detection of SARS-CoV-2	68
Extraction-free SARS-CoV-2 detection by rapid RT-qPCR universal for all primary respiratory materials	68
Comparison of the analytical sensitivity of seven commonly used commercial SARS-CoV-2 automated molecular assays	68
Clinical features of pediatric patients with coronavirus disease (COVID-19)	67
Rapid and sensitive detection of SARS-CoV-2 RNA using the Simplexa™ COVID-19 direct assay	66
Validation of SARS-CoV-2 detection across multiple specimen types	63
Evaluation of three rapid lateral flow antigen detection tests for the diagnosis of SARS-CoV-2 infection	62
Epidemiological and clinical features of 200 hospitalized patients with corona virus disease 2019 outside Wuhan, China: A descriptive study	62
Multiplex detection and dynamics of IgG antibodies to SARS-CoV2 and the highly pathogenic human coronaviruses SARS-CoV and MERS-CoV	62
Challenges of Convalescent Plasma Therapy on COVID-19	61
SARS-CoV-2-IgG response is different in COVID-19 outpatients and asymptomatic contact persons	60
Use of the variplex™ SARS-CoV-2 RT-LAMP as a rapid molecular assay to complement RT-PCR for COVID-19 diagnosis	60
Comparison of commercial lateral flow immunoassays and ELISA for SARS-CoV-2 antibody detection	59
Epidemiological and initial clinical characteristics of patients with family aggregation of COVID-19	57
Saliva sampling for diagnosing SARS-CoV-2 infections in symptomatic patients and asymptomatic carriers	56
Clinical evaluation of the BioFire® Respiratory Panel 2.1 and detection of SARS-CoV-2	56

Persistent detection of SARS-CoV-2 RNA in patients and healthcare workers with COVID-19	55
Evaluation of rapid antigen detection kit from the WHO Emergency Use List for detecting SARS-CoV-2	55
SARS-CoV-2 antibodies, serum inflammatory biomarkers and clinical severity of hospitalized COVID-19 patients	55
Comparison of SARS-CoV-2 serological tests with different antigen targets	55
Evaluation of simple nucleic acid extraction methods for the detection of SARS-CoV-2 in nasopharyngeal and saliva specimens during global shortage of extraction kits	52
Rapid random access detection of the novel SARS-coronavirus-2 (SARS-CoV-2, previously 2019-nCoV) using an open access protocol for the Panther Fusion	52
Community-acquired viral respiratory infections amongst hospitalized inpatients during a COVID-19 outbreak in Singapore: co-infection and clinical outcomes	52
Clinical evaluation of a SARS-CoV-2 RT-PCR assay on a fully automated system for rapid on-demand testing in the hospital setting	52
Clinical evaluation of five different automated SARS-CoV-2 serology assays in a cohort of hospitalized COVID-19 patients	51
Comparison of eight commercial, high-throughput, automated or ELISA assays detecting SARS-CoV-2 IgG or total antibody	51
SARS-CoV-2 viral load assessment in respiratory samples	51
Analysis of Covid-19 and non-Covid-19 viruses, including influenza viruses, to determine the influence of intensive preventive measures in Japan	50
Pooling of SARS-CoV-2 samples to increase molecular testing throughput	49
Modeling the effects of intervention strategies on COVID-19 transmission dynamics	48
Saliva specimens for detection of severe acute respiratory syndrome coronavirus 2 in Kuwait: A cross-sectional study	48
A SARS-CoV-2 Nucleocapsid Variant that Affects Antigen Test Performance	47
Another false-positive problem for a SARS-CoV-2 antigen test in Japan	46
Implementation of rapid SARS-CoV-2 antigenic testing in a laboratory without access to molecular methods: Experiences of a general hospital	45
Diagnostic accuracy and feasibility of patient self-testing with a SARS-CoV-2 antigen-detecting rapid test	45
A predictive tool for identification of SARS-CoV-2 PCR-negative emergency department patients using routine test results	45
SARS-CoV-2 rapid antigen test: High sensitivity to detect infectious virus	45
Immune response to SARS-CoV-2 in health care workers following a COVID-19 outbreak: A prospective longitudinal study	44
Comparison of different serological assays for SARS-CoV-2 in real life	44
Use of dried blood spot samples for SARS-CoV-2 antibody detection using the Roche Elecsys ® high throughput immunoassay	44
Validation and verification of the Abbott RealTime SARS-CoV-2 assay analytical and clinical performance	44
Comparison of the Panther Fusion and a laboratory-developed test targeting the envelope gene for detection of SARS-CoV-2	44
Comparing the diagnostic accuracy of rapid antigen detection tests to real time polymerase chain reaction in the diagnosis of SARS-CoV-2 infection: A systematic review and meta-analysis	44
Evaluation of the commercially available LightMix® Modular E-gene kit using clinical and proficiency testing specimens for SARS-CoV-2 detection	44
Diagnostic performance of a SARS-CoV-2 rapid antigen test in a large, Norwegian cohort	43
Interpret with caution: An evaluation of the commercial AusDiagnostics versus in-house developed assays for the detection of SARS-CoV-2 virus	40
Alltest rapid lateral flow immunoassays is reliable in diagnosing SARS-CoV-2 infection from 14 days after symptom onset: A prospective single-center study	40
Clinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus.	40
Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure	40
Evaluation of the RealStar® SARS-CoV-2 RT-PCR kit RUO performances and limit of detection	39
SARS-CoV-2: Is it the newest spark in the TORCH?	39
Recommendations for the introduction of metagenomic next-generation sequencing in clinical virology, part II: bioinformatic analysis and reporting	39
Maternal type of CMV infection and sequelae in infants with congenital CMV: Systematic review and meta-analysis	39
Ad hoc laboratory-based surveillance of SARS-CoV-2 by real-time RT-PCR using minipools of RNA prepared from routine respiratory samples	38
First results of a national external quality assessment scheme for the detection of SARS-CoV-2 genome sequences	38
Comparison of a laboratory-developed test targeting the envelope gene with three nucleic acid amplification tests for detection of SARS-CoV-2	38
Clinical predictors and timing of cessation of viral RNA shedding in patients with COVID-19	36
A RT-PCR assay for the detection of coronaviruses from four genera	36
A comparative evaluation between the Abbott Panbio™ COVID-19 IgG/IgM rapid test device and Abbott Architect™ SARS CoV-2 IgG assay	36
Handling and accuracy of four rapid antigen tests for the diagnosis of SARS-CoV-2 compared to RT-qPCR	36
Improved diagnosis of viral encephalitis in adult and pediatric hematological patients using viral metagenomics	35
Clinical COVID-19 diagnostic methods: Comparison of reverse transcription loop-mediated isothermal amplification (RT-LAMP) and quantitative RT-PCR (qRT-PCR)	35
Development of a point-of-care test to detect SARS-CoV-2 from saliva which combines a simple RNA extraction method with colorimetric reverse transcription loop-mediated isothermal amplification detect	35
Detection of low levels of SARS-CoV-2 RNA from nasopharyngeal swabs using three commercial molecular assays	34
Single-step RT-PCR assay for dual genotyping of GI and GII norovirus strains	34
Accuracy of COVID-19 rapid antigenic tests compared to RT-PCR in a student population: The StudyCov study	33
Multiplexing primer/probe sets for detection of SARS-CoV-2 by qRT-PCR	33
SARS-CoV-2 antibody screening in healthcare workers in a tertiary centre in North West England	33
Diagnostic performance of CerTest and Panbio antigen rapid diagnostic tests to diagnose SARS-CoV-2 infection	33
Evaluation of nCoV-QS (MiCo BioMed) for RT-qPCR detection of SARS-CoV-2 from nasopharyngeal samples using CDC FDA EUA qPCR kit as a gold standard: An example of the need of validation studies	32
Nosocomial outbreak of SARS-CoV-2 infection in a haematological unit – High mortality rate in infected patients with haematologic malignancies	32
Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19	32
Five-minute point-of-care testing for SARS-CoV-2: Not there yet	32
Acute bronchiolitis and respiratory syncytial virus seasonal transmission during the COVID-19 pandemic in Spain: A national perspective from the pediatric Spanish Society (AEP).	32
Neutralizing antibody responses following natural SARS-CoV-2 infection: Dynamics and correlation with commercial serologic tests.	31
Human Calicivirus Typing tool: A web-based tool for genotyping human norovirus and sapovirus sequences	31
Consistency analysis of COVID-19 nucleic acid tests and the changes of lung CT	31
Impaired performance of SARS-CoV-2 antigen-detecting rapid diagnostic tests at elevated and low temperatures	30
Evaluation of two RT-PCR screening assays for identifying SARS-CoV-2 variants	30
Evaluation of the Aptima™ transcription-mediated amplification assay (Hologic®) for detecting SARS-CoV-2 in clinical specimens	29
Head-to-head comparison of two rapid high-throughput automated electrochemiluminescence immunoassays targeting total antibodies to the SARS-CoV-2 nucleoprotein and spike protein receptor binding domai	29
SARS-CoV-2 infection among asymptomatic healthcare workers of the emergency department in a tertiary care facility	29
Antibody response to SARS-CoV-2 for more than one year − kinetics and persistence of detection are predominantly determined by avidity progression and test design	29
Analytical performance of HPV assays on vaginal self-collected vs practitioner-collected cervical samples: the SCoPE study	29
Severity of coronavirus respiratory tract infections in adults admitted to acute care in Toronto, Ontario	29
Benchmark of thirteen bioinformatic pipelines for metagenomic virus diagnostics using datasets from clinical samples	29
Coronavirus discovery by metagenomic sequencing: a tool for pandemic preparedness	29
Torque teno virus loads after kidney transplantation predict allograft rejection but not viral infection	29
Breakthrough COVID-19 and casirivimab-imdevimab treatment during a SARS-CoV-2 B1.617.2 (Delta) surge	28
Evaluation of an antigen-based test for hospital point-of-care diagnosis of SARS-CoV-2 infection	28
Development of a rapid point-of-care test that measures neutralizing antibodies to SARS-CoV-2	27
Rapid implementation and validation of a cold-chain free SARS-CoV-2 diagnostic testing workflow to support surge capacity	27
Contribution of VitaPCR SARS-CoV-2 to the emergency diagnosis of COVID-19	27
Current studies of convalescent plasma therapy for COVID-19 may underestimate risk of antibody-dependent enhancement	27
ACE2, COVID19 and serum ACE as a possible biomarker to predict severity of disease	26
Coronavirus disease 2019 in children: Characteristics, antimicrobial treatment, and outcomes	26

Detection of SARS-COV N2 Gene: Very low amounts of viral RNA or false positive?	26
Implementation of an in-house real-time reverse transcription-PCR assay for the rapid detection of the SARS-CoV-2 Marseille-4 variant	26
Use of a simplified sample processing step without RNA extraction for direct SARS-CoV-2 RT-PCR detection	25
Utilizing tocilizumab for the treatment of cytokine release syndrome in COVID-19	25
Human Bocavirus infection and respiratory tract disease identified in a UK patient cohort	25
Pushing beyond specifications: Evaluation of linearity and clinical performance of the cobas 6800/8800 SARS-CoV-2 RT-PCR assay for reliable quantification in blood and other materials outside recommen	25
Clinical performance of the GenMark Dx ePlex respiratory pathogen panels for upper and lower respiratory tract infections	25
Clinical evaluation of AusDiagnostics SARS-CoV-2 multiplex tandem PCR assay	25
Dynamics of IgG-avidity and antibody levels after Covid-19	24
Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7	24
Comparison of the GeneFinderTM COVID-19 Plus RealAmp Kit on the sample-to-result Platform ELITe InGenius to the national reference method: An added value of N gene target detection?	23
COVID-19 in Vietnam: A lesson of pre-preparation	23
Evolution of awareness and knowledge of congenital cytomegalovirus infection among health care providers in France between 2011 and 2018	23
Rapid screening method for the detection of SARS-CoV-2 variants of concern	23
Rapid and simultaneous identification of three mutations by the Novaplex™ SARS-CoV-2 variants I assay kit	22
Evaluation on testing of deep throat saliva and lower respiratory tract specimens with Xpert Xpress SARS-CoV-2 assay	22
RSV reemergence in Argentina since the SARS-CoV-2 pandemic	22
Development of the RealTime SARS-CoV-2 quantitative Laboratory Developed Test and correlation with viral culture as a measure of infectivity	21
Performance evaluation of two SARS-CoV-2 IgG/IgM rapid tests (Covid-Presto and NG-Test) and one IgG automated immunoassay (Abbott)	21
Detection of SARS-CoV-2 variants by Abbott molecular, antigen, and serological tests	21
Extraction-free RT-LAMP to detect SARS-CoV-2 is less sensitive but highly specific compared to standard RT-PCR in 101 samples	20
Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers	20
Rapid SARS-CoV-2 variant monitoring using PCR confirmed by whole genome sequencing in a high-volume diagnostic laboratory	20
Multicenter evaluation of the NeuMoDx™ SARS-CoV-2 Test	20
Interactions between seasonal human coronaviruses and implications for the SARS-CoV-2 pandemic: A retrospective study in Stockholm, Sweden, 2009-2020	20
Human coronaviruses: Origin, host and receptor	20
Correlation between monkeypox viral load and infectious virus in clinical specimens	20
Investigating the genomic landscape of novel coronavirus (2019-nCoV) to identify non-synonymous mutations for use in diagnosis and drug design	20
Valacyclovir in primary maternal CMV infection for prevention of vertical transmission: A case-series	19
Reliable quantification of plasma HDV RNA is of paramount importance for treatment monitoring: A European multicenter study	19
Clinical application of Chemiluminescence Microparticle Immunoassay for SARS-CoV-2 infection diagnosis	19
Analysis of cycle threshold values in SARS-CoV-2-PCR in a long-term study	19
Comparative evaluation of SARS-CoV-2 IgG assays in India	19
Challenges of aciclovir-resistant HSV infection in allogeneic bone marrow transplant recipients	19
Immunologic response, Efficacy, and Safety of Vaccines against COVID-19 Infection in Healthy and immunosuppressed Children and Adolescents Aged 2 – 21 years old: A Systematic Review and Meta-analysis	19
Plaque-neutralizing antibody to BA.2.12.1, BA.4 and BA.5 in individuals with three doses of BioNTech or CoronaVac vaccines, natural infection and breakthrough infection	19
Prospective evaluation of ID NOW COVID-19 assay used as point-of-care test in an emergency department	18
Focusing on severe infections with the respiratory syncytial virus (RSV) in adults: Risk factors, symptomatology and clinical course compared to influenza A / B and the original SARS-CoV-2 strain	18
The 2019 HPV Labnet international proficiency study: Need of global Human Papillomavirus Proficiency Testing	18
Redondovirus DNA in human respiratory samples	18
SARS-CoV-2 whole-genome sequencing using reverse complement PCR: For easy, fast and accurate outbreak and variant analysis.	18
Accuracy and real life performance of a novel interferon-γ release assay for the detection of SARS-CoV2 specific T cell response	18
RT-PCR based SARS-CoV-2 variant screening assays require careful quality control	17
NVX-CoV2373-induced cellular and humoral immunity towards parental SARS-CoV-2 and VOCs compared to BNT162b2 and mRNA-1273-regimens	17
Improved oral detection is a characteristic of Omicron infection and has implications for clinical sampling and tissue tropism	17
Multicenter comparison of the Cobas 6800 system with the RealStar RT-PCR kit for the detection of SARS-CoV-2	17
Comparison of SARS-CoV-2 detection from combined nasopharyngeal/oropharyngeal swab samples by a laboratory-developed real-time RT-PCR test and the Roche SARS-CoV-2 assay on a cobas 8800 instrument	16
Evaluation of the clinical and analytical performance of the Seegene allplex™ SARS-CoV-2 variants I assay for the detection of variants of concern (VOC) and variants of interests (VOI)	16
Unusual, neurological and severe dengue manifestations during the outbreak in Sri Lanka, 2017	16
The diagnosis of pandemic coronavirus pneumonia: A review of radiology examination and laboratory test	16
The implications of preliminary screening and diagnosis: Clinical characteristics of 33 mild patients with SARS-CoV-2 infection in Hunan, China	16
Epidemiological characteristics and clinical outcomes of human rhinovirus infections in a hospitalized population. Severity is independently linked to RSV coinfection and comorbidities	16
Evidence of tenofovir resistance in chronic hepatitis B virus (HBV) infection: An observational case series of South African adults	16