OOIR: Observatory of International Research

Papers

(The TQCC of Current Organic Chemistry is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Advances in the Synthesis of Diarylpyrimidine as Potent Non-nucleoside Reverse Transcriptase Inhibitors: Biological Activities, Molecular Docking Studies and Structure-activity Relationship: A Critica	47
Modification for Nitration of Halo-substituted meso-Tetraarylporphyrins: A Convenient Scale-up in Small Amount of Solvent	28
Structural Metamorphosis: Rearranging Camphor-based Systems	27
Cationic Ruthenium for C-H Activation Reactions	25
Harnessing the Pyrazine Moiety for Potent Anti-inflammatory Activity: A Comprehensive Review	24
Azobenzene as an Anti-microbial Scaffold: A Comprehensive Review	24
Friedel Crafts Reactions Revisited: Some Applications in Heterogeneous Catalysis#	23
Design, Synthesis, Reactions, Molecular Docking, Antitumor Activities of Novel Naphthopyran, Naphthopyranopyrimidines, and Naphthoyranotriazolopyrimidine Derivatives	21
An Insight into the Anti-Cancer Potential of N-Heterocyclic Compounds Targeting Breast Cancer	20
Design and Synthesis of Pyrimidine-Based Heteroaryl Compounds and their Applications for the Treatment of Cancer	20
Synthesis of N-Heterocycles and Linear Adducts from Allyl-Containing Substrates and Sulfonamides	20
Recent Research on Lipase Immobilization with Multipoint Covalent Treatment by Glutaraldehyde	20
Growing Impact of Bioorthogonal Click Chemistry in Cell Surface Glycan Labeling	19
Recent Achievements in the Synthesis of Carbazole Derivatives	19
Trihaloisocyanuric Acids: Useful Reagents for Halogenation Reactions and Heterocyclic Scaffold Construction	19
Synthetic Approaches to Bis- and Tris-Thiazole Derivatives via Hydrazonoyl Halides and Thiosemicarbazones (2015-2025)	18
Cruzain Inhibitors: State-of-Art of Novel Synthetic Strategies	18
Recent Achievement in the Synthesis of Imidazoles	18
Synthesis and Biological Evaluation of Heterocyclic Compounds	17
Synthetic Development in Inulin Modification and its Applications	17
Pyrazole and Benzimidazole Derivatives: Chelating Properties Towards Metals Ions and their Applications	17
Synthesis of Polynuclear Aromatic Hydrocarbons by Palladium-catalyzed C-H Bond Functionalization	17
Oligomers Electrosynthesis: A Selective and Greener Synthetic Tool	17
Tris(pentafluorophenyl)borane [B(C₆F₅)₃]-catalyzed Organic Transformations: A Triennial Update (2021 Onwards)	17
Recent Advancements in the Synthesis of Thiazole Derivatives with Promising Anti-Breast Cancer Activity	17

A Novel Cu(II)-Iodine Catalyzed Hantzsch Type Synthesis of 2-Aminothiazole Derivatives	17
Merrifield Resin Supported Ionic Liquids: Catalytic Applications in Organic Synthesis	16
Synthesis and Gas Permeation Properties of Functionalized Norbornene-Based Polymers	16
A Review on Piezoelectric-mediated Mechanoredox Reactions by Ball Milling in Organic Synthesis	16
An Overview of Recent Advances in Isatin-Based Multicomponent Reactions	16
Antileishmanial Activity of Natural Diterpenoids: A Comprehensive Review	16
Non-conventional Approaches Towards Various Organic Transformations – (Part 1)	16
Perspectives in Future Applications and Advancements of NMR Spectroscopy	16
Hedychium coronariumJ. Koenig: Traditional Uses, Phytochemistry, Biological Activities and Future Aspects	15
Functional Chitosan: Recent Gamma Radiation Chemistry of Organic Derivatives	14
Acknowledgements to Reviewers	14
Asymmetric Catalysis: Intramolecular Haloamination of Alkenes - A Perspective	14
Light-responsive Polymers: Developments in Drug Delivery Systems	14
Ultrasound-assisted Synthesis of Biologically Promising Organoselenium Scaffolds	13
Edible Oils and Development of New Products: Sensory, Microbiological, and Cytotoxic Aspects	13
Advances in Theobromine Derivatives for Cancer Treatment: Synthesis Strategies and Biological Effects	13
Anthracycline in Medicinal Chemistry: Mechanism of Cardiotoxicity, Preventive and Treatment Strategies	13
Dipeptide Sulfonamides: Synthesis and Pharmacological Activities	13
Recent Developments in the Transformation of 3-amino-2-azetidinones	12
Synthesis of Pregna-1,4,16-triene-3,20-dione from a Mixture of Soybean Phytosterols using a Combination of Chemical and Microbiological Methods	12
Current Status and Applications of Gamma Radiation-induced Graft Copolymerized Chitosan	12
NMR and FT-IR Investigation Study and Topological Analysis of Various Conformations of 2,5-dimethyl-2,5-dihydroxyl-1,4-dithian using Density Functional Theory Method	12
Synthesis of Epichlorohydrin-based Click-dendrons with Different Functional Groups	12
Catalysts For Propargylamines Synthesis Via A3, AHA, and KA2 Coupling - A Review	12
Mechanisms, Copper Catalysts, and Ligands Involved in the Synthesis of 1,2,3- Triazoles Using Click Chemistry	12
Phytochemical, Pharmacological Profile and Biotechnology Approaches in the Production of Coriandrum sativum Linn.	11
Recently Published Patents on Janus Base Nanomaterials for RNA Delivery	11
Novel 2-Acetanilide 2-Arylquinoline-4-carboxylates as Antileishmanial Agents: From Prediction to In Vitro Activity/Toxicity	11
Efficient Synthesis and Characterization of 6-substituted-N-p-tolyl-imidazo[1,2- a]pyridine-8-carboxamide: A Promising Scaffold for Drug Development	11
Electrochemistry: A Versatile Tool for Organic Synthesis	11
Application of Biosensors for Pesticide Analysis: Classification, Toxicity, Environmental Impact, Detection Techniques, and Mode of Action	11
Biological Roles and Pharmaceutical Applications of Metal-Complexed Coumarin Derivatives: A Comprehensive Review	11
Bioactive Compounds from Polar Regions: An Account of Chemical Ecology and Biotechnological Applications	11
Ruthenium-catalyzed Aromatic meta-C-H Nitration of 1,2,4-thiadiazoles	11
1,4-Diazabicyclo[2.2.2]octane (DABCO) in Organic Synthesis and Catalysis: A Quinquennial Report (2019-to Date)	11
Recent Advances on the α-Functionalization and Ring Transformations of Cycloheptane-based β-ketoesters	11
Recent Advancements in Glycosylation Reactions: An Access to Privileged C- and S-glycosides	11
Advances in Nickel-Metallaphotoredox Catalysis in Organic Synthesis: A New Approach to Targeted Reaction Design	10
Ulmus Species: Their Extraction, Structural Diversity, and Pharmacological Properties	10
Phytochemistry, Pharmacological Targets, Biological Mechanisms and Patented Formulations of Salacia reticulata Wight (Celastaceae): An Appraisal of its Potential	10
Recent Advances in the Synthesis and Applications of Partially Protected N-Glycosylamines	10
Non-conventional Approaches towards Various Organic Transformations – (Part II)	10
New Insights into Organic Chemistry (Part 2)	10
Synthesis, Characterization, and Molecular Docking of Novel Isatin-thiosemicarbazone Containing 1,2,3-triazole Derivatives as Potential Anti-cancer Agents	10
An Overview of Recent Advances in Cobalt-Catalyzed C-H Functionalization of Unactivated Aromatic/Aliphatic Compounds	10
A Pharmacological Update of Acridine Derivatives: A Mini-Review	10
Synthesis of Polyoxygenated 4,5-Diarylpyridazines with Antiproliferative and Antitubulin Activity via Inverse Electron-Demand Diels-Alder Reaction of 1,2,4,5- Tetrazine	10
“Green” Synthesis of Substituted Tetraketones with Prominent Bactericide Effect	10
Comparative Study on Catalysis Strategies: Friedel-Crafts Alkylation vs. Michael Addition of Indoles to Nitroalkenes	10
Ultrasound-assisted Synthesis of Nitrogen and Oxygen Containing Heterocycles	10

Green Synthesis and Acetylcholinesterase Inhibition of Coumarin-1,2,4-Triazole Hybrids	9
Phytochemical Composition and Mechanistic Pharmacology of the Citrus Genus: Focus on Organic Constituents	9
4-Aminocoumarin Derivatives as Multifaceted Building Blocks for the Development of Various Bioactive Fused Coumarin Heterocycles: A Brief Review	9
Synthesis of Stemona Alkaloids: A Comprehensive Review	9
Modified Synthesis and Isolation of an Advanced Intermediate of Remdesivir	9
Recent Advances in Biocatalytic Acylation of Alcohols as a Sustainable Target for Flavor and Fragrance Compounds	9
Regioselectivity Inversion in Hydroformylation of Aryl Alkenes with a Diphosphoramidite-rhodium Catalyst	9
Recent Insights into the Synthesis of Oligosaccharides from Escherichia coli: Review	9
N-Silylmethyl-2-(1-Naphthyl)Acetamides: Synthesis, Structure and Computational Screening	9
Coumarin Derivatives: Pioneering New Frontiers in Biological Applications	9
Synthetic Strategies to Substituted Chiral Furans: A Review	9
A Comprehensive Insight into the Synthetic Pathways to Tetrahydrobenzoxazepines, Tetrahydrobenzothiazepines, and Tetrahydrobenzoimidazoazepines	9
Recent Advances in Palladium-Catalyzed C-C Cross-Coupling Reactions: An Overview	9
Kojic Acid - A Blossoming Scaffold of Biological Significance: An Overview of Synthesis, Properties, and Biological Applications	9
Green Synthesis of Pyridine and their Fused System: Harnessing the Catalytic Power of Ionic Liquids for Sustainable and Efficient Multicomponent Reaction	9
Synthesis, Characterization, Molecular Docking Studies and Biological Evaluation of Some Novel 3,5-disubstituted-1-phenyl-4,5-dihydro-1H-pyrazole Derivatives	9
Preface	9
Facile Synthesis of Organic Compounds in PEG, ScCO₂ and H₂O: A Review	9
Effects of Catalysts, Solvents, and Temperature on Nenitzescu Reaction	8
Connection Number-based Multiplicative Zagreb Indices of Chemical Structures	8
Direct Catalytic Conversion of Biomass-derived Carbohydrates to Ethyl Levulinate	8
Recent Progress of Calcium-Based Catalysts in Organic Transformations	8
Design, Synthesis, Antimicrobial Activity and Molecular Docking of Novel Pyridine, Thiophene, and Thiadiazole Scaffolds Utilizing 2-Cyano-N-(4-(1-(2-(2-cyanoacetyl) hydrazineylidene)ethyl)phenyl)aceta	8
A Review on Traditional and Modern Methods for the Synthesis of Aromatic Azo Compounds	8
Synthesis of Novel Derivatives of Dissymmetric Bisarylidene of Tetrahydro-4H-pyran-4-one	8
Construction of C-S and C-Se Bonds Mediated by Hypervalent Iodine Reagents Under Metal-Free Conditions	8
Recent Advancements in the Synthesis of Pyrazole Derivative for the Treatment of Alzheimer's Disease	8
The Chemical Synthesis of the 1-C-Alkyl Substituted Pyrrolidine and Piperidine Iminosugar Natural Products and their Analogues	8
Bioisosteric Replacement through 1,2,3-triazolyl Linkage Significantly Potentiate Biological Activity in Lidocaine and Etidocaine Analogs: Rational Design and Local Anesthetic Activity	8
Green Methodologies for the Synthesis of Thiophene Chalcone Derivatives: A Review	8
Application of Ionic Liquids in Environmental and Food Fields	8
Therapeutic Advances of Phytochemicals and Clinical Trials in Renal Cell Carcinoma: Evidence from 2019-2025	8
A New Perspective on the Molecular Targets, Mechanisms of Action, and Clinical Significance of Ursolic Acid’s Multifaceted Anti-cancer Effects	8
A Review on Green Synthesis and Biological Activities of Medicinally Important Nitrogen and Oxygen Containing Heterocycles	8
Microwave Assisted Grafting Technique for Modification of Polysaccharides	8
Triazines as Versatile Scaffolds in Drug Discovery: A Comprehensive Review on Recent Advances and Emerging Therapeutic Applications	8
Recent Advances in Smart Polymers	7
Synthesis of 1,4-Benzodiazepines by Palladium-Catalyzed C-N Coupling	7
Theoretical Study of Methylaluminoxane Formation	7
The Direct use of Metallic Ore Minerals as Catalysts in Organic Syntheses	7
Recent Progress in the Synthetic Methods of Pyrazoloquinoline Derivatives	7
1,3,5 and 1,2,4-triazines as Potent Scaffolds for Molecules Potentially Attenuating Breast Cancer Cell Lines	7
Applications of Transesterification in the Synthesis of Commercial and Noncommercial β -Ketoesters/Esters, Medicinally Important Heterocycles and Production of Biodiesel	7
Interesting Metformin-based Derivatives with Versatile Pharmacology	7
Preface	7
Utility of Palladium as a Catalyst for the Synthesis of Five and Six-Membered Heterocyclic Moieties	7
An Expeditious Synthesis of Ethyl-2-(4-(arylmethylene)-5-oxo-4,5-dihydroisoxazol-3- yl)acetate Derivatives	7
Preface	7
A Comprehensive Review on the Synthesis of Mangiferin Derivatives and their Multiple Biological Activities	7
A Visible-Light-Induced Cyclization Reaction	7
Synthesis, Thermotropic Properties, and Applications of Porphyrin-based Liquid Crystals: A Comprehensive Review	7
Cholapod and Cholaphanes for Recognition of Anions	7
Di-tert-butyl Peroxide (DTBP)-Promoted Heterocyclic Ring Construction	7
5-Aminotetrazoles – An Overview of Synthetic Methodologies through the Desulfurization of Thioureas	7
Recent Innovations in Synthetic Methodologies and Patent Landscape of Quinoline Analogues: A Comprehensive Review	7
Recent Insights into Benzimidazole Derivatives: From Synthesis to Medicinal Applications	7
Synthesis, Biological Activity and DFT Studies of 1,3,4-oxadiazole Ring in Combination with Pyridinium Salt	7
Triazole: A New Perspective in Medicinal Chemistry and Material Science	7
Catalytic Syntheses of Pyrano[3,2-c]Quinolone and -Quinoline Derivatives and their Potential Therapeutic Agents	7