OOIR: Observatory of International Research

Papers

(The TQCC of Mutation Research-Genetic Toxicology and Environmental Mutagenesis is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Cancer risk following low doses of ionising radiation – Current epidemiological evidence and implications for radiological protection	35
Mechanisms underlying the pathophysiology of type 2 diabetes: From risk factors to oxidative stress, metabolic dysfunction, and hyperglycemia	33
Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?	21
Mitomycin C induced genotoxic stress in endothelial cells is associated with differential expression of proinflammatory cytokines	19
N-acetyl-l-cysteine mediated regulation of DNA fragmentation, an apoptotic event, against methoxychlor toxicity in the granulosa cells of ovarian antral follicles	19
Key read across framework components and biology based improvements	18
Pro-inflammatory response and genotoxicity caused by clay and graphene nanomaterials in A549 and THP-1 cells	18
Crosstalk between different DNA repair pathways for DNA double strand break repairs	18
Measurement of oxidatively damaged DNA in mammalian cells using the comet assay: Reflections on validity, reliability and variability	17
EURL ECVAM Genotoxicity and Carcinogenicity Database of Substances Eliciting Negative Results in the Ames Test: Construction of the Database	16
Strategies in genotoxicology: Acceptance of innovative scientific methods in a regulatory context and from an industrial perspective	15
Genotoxic and cytotoxic properties of two medical plants (Teucrium arduini L.and Teucrium flavum L.) in relation to their polyphenolic contents	14
Cadmium selenide (CdSe) quantum dots cause genotoxicity and oxidative stress in Allium cepa plants	14
Establishment and multiparametric-cytogenetic validation of 60Co-gamma-ray induced, phospho-gamma-H2AX calibration curve for rapid biodosimetry and triage management during radiological emergencies	14
Genotoxicity of selected pyrrolizidine alkaloids in human hepatoma cell lines HepG2 and Huh6	14
Genotoxicity and cellular uptake of nanosized and fine copper oxide particles in human bronchial epithelial cells in vitro	13
Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks	12
The 3D reconstructed skin micronucleus assay using imaging flow cytometry and deep learning: A proof-of-principle investigation	12
Differential effects of cisplatin combined with the flavonoid apigenin on HepG2, Hep3B, and Huh7 liver cancer cell lines	12
TiO2 genotoxicity: An update of the results published over the last six years	12
Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase	11
Influence of bariatric surgery induced weight loss on oxidative DNA damage	11
Gasoline-station workers in Brazil: Benzene exposure; Genotoxic and immunotoxic effects	11
Ionizing radiation, genotoxic stress, and mitochondrial DNA copy-number variation in Caenorhabditis elegans: droplet digital PCR analysis	10
Calibration of the comet assay using ionising radiation	10

Induction of genotoxicity and mutagenic potential of heavy metals in Thai occupational workers	9
Genotoxicant exposure, activation of the aryl hydrocarbon receptor, and lipid peroxidation in cultured human alveolar type II A549 cells	9
Loci associated with genomic damage levels in chronic kidney disease patients and controls	9
Genotoxicity of three mycotoxin contaminants of rice: 28-day multi-endpoint assessment in rats	9
Smoking, chromosomal aberrations, and cancer incidence in healthy subjects	9
Alternariol monomethyl ether toxicity and genotoxicity in male Sprague-Dawley rats: 28-Day in vivo multi-endpoint assessment	8
Genomic instability in people living with HIV	8
Genotoxic effects of silver nanoparticles on a tropical marine amphipod via feeding exposure	8
Increased micronucleus frequencies in reticulocytes of children exposed to industrial pollution: oxidative stress and the OGG1 S326C polymorphism	7
Mode of action assessment of the genotoxic properties of antimony and its compounds evaluated in the ToxTracker assay	7
Mechanism of reactive oxygen species generation and oxidative DNA damage induced by acrylohydroxamic acid, a putative metabolite of acrylamide	7
Genetic damage in coal and uranium miners	7
2-Methylfuran: Toxicity and genotoxicity in male Sprague-Dawley rats	7
New insight into the antigenotoxic activity of Gentiana lutea extracts – Protective effect against food borne mutagens	7
D-10-camphorsulfonic acid: Safety evaluation	6
Cytogenetic monitoring of peripheral blood lymphocytes from medical radiation professionals occupationally exposed to low-dose ionizing radiation	6
Genotoxicity of the organophosphate pesticide malathion and its metabolite dimethylthiophosphate in human cells in vitro	6
Evaluation of genotoxic damage in buccal mucosa cytome assays in Iraqi school children exposed to air pollutants emanating from oil fields	6
Consumption pattern and genotoxic potential of various smokeless tobacco products in Assam, India: A public health concern	6
Mutagenicity of N-acyloxy-N-alkoxyamides as an indicator of DNA intercalation: The role of fluorene and fluorenone substituents as DNA intercalators	6
Benchmark dose analyses of γH2AX and pH3 endpoints for quantitative comparison of in vitro genotoxicity potential of lipophilic phycotoxins	6
Use of the alkaline comet assay for monitoring genotoxic effects of arsenic in human populations	6
Exposure of patients to low doses of X-radiation during neuro-interventional imaging and procedures: Dose estimation and analysis of γ-H2AX foci and gene expression in blood lymphocytes	6
Genotoxicity studies with an ethanolic extract of Kalanchoe pinnata leaves	6
Synephrine and caffeine combination promotes cytotoxicity, DNA damage and transcriptional modulation of apoptosis-related genes in human HepG2 cells	5
Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug-related metabolite, or drug-	5
Repurposing sodium diclofenac as a radiation countermeasure agent: A cytogenetic study in human peripheral blood lymphocytes	5
Effects of sulforaphane on the oxidative response, apoptosis, and the transcriptional profile of human stomach mucosa cells in vitro	5
Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence	5
High homocysteine promotes telomere dysfunction and chromosomal instability in human neuroblastoma SH-SY5Y cells	5
Exposure to hypomethylating 5-aza-2′-deoxycytidine (decitabine) causes rapid, severe DNA damage, telomere elongation and mitotic dysfunction in human WIL2-NS cells	5
Short- and long-term reproducibility of the COMET assay for measuring DNA damage biomarkers in frozen blood samples of the EPIC-Heidelberg cohort	5
Investigations on the new mechanism of action for acetaldehyde-induced clastogenic effects in human lung fibroblasts	5
Shortened telomere length in peripheral blood leukocytes of patients with lung cancer, chronic obstructive pulmonary disease in a high indoor air pollution region in China	5
Low dose radiation mechanisms: The certainty of uncertainty	5
Toxicity screening of air extracts representing different source sectors in the Greater Toronto and Hamilton areas: In vitro oxidative stress, pro-inflammatory response, and toxicogenomic analysis	5
Emerging roles of DNA topoisomerases in the regulation of R-loops	5
In vitro toxicity and internalization of gold nanoparticles (AuNPs) in human epithelial colorectal adenocarcinoma (Caco-2) cells and the human skin keratinocyte (HaCaT) cells	4
In vitro genotoxicity assessment of graphene quantum dots nanoparticles: A metabolism-dependent response	4
Genotoxicity test battery – An assessment of its utility in early drug development	4
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide	4
Molecular analysis of GPI-anchor biosynthesis pathway genes in rat strains used for the Pig-a gene mutation assay	4
Epigenetic effects of graphene oxide and its derivatives: A mini-review	4
Genomic instability evaluation by BMCyt and telomere length in Brazilian family farmers exposed to pesticides	4
Brazilian workers occupationally exposed to different toxic agents: A systematic review on DNA damage	4
Retrospective cytogenetic analysis of unstable and stable chromosome aberrations in the victims of radiation accident in Bulgaria	4
Evaluation of the genotoxic potential of apoptosis inducers with the γH2AX assay in human cells	4
Effects of isolated and combined exposures of Boana curupi (Anura: Hylidae) tadpoles to environmental doses of trichlorfon and ultraviolet radiation	4
Comprehensive review of genotoxicity data for diclofenac	4
Ex vivo/in vitro effects of aspirin and ibuprofen, bulk and nano forms, in peripheral lymphocytes of prostate cancer patients and healthy individuals	4

Guidance for publishing comet assay results	4
Women rag pickers at a dump in Ahmedabad: Genotoxicity and oxidative stress	4
Maternal overnutrition before and during pregnancy induces DNA damage in male offspring: A rabbit model	4
Ionizing radiation-induced genotoxic and oxidative damage in peripheral lymphocytes and plasma of healthy donors	4
Cytotoxicity and genotoxicity of blue LED light and protective effects of AA2G in mammalian cells and associated DNA repair deficient cell lines	4
Analysis of chromosomal aberrations and γH2A.X foci to identify radiation-sensitive ataxia-telangiectasia patients	4
Evaluation of the genotoxic and cytotoxic effects of exposure to the herbicide 2,4-dichlorophenoxyacetic acid in Astyanax lacustris (Pisces, Characidae) and the potential for its removal from contamin	4