Mutation Research-Genetic Toxicology and Environmental Mutagenesis

Article	Citations
Mechanisms underlying the pathophysiology of type 2 diabetes: From risk factors to oxidative stress, metabolic dysfunction, and hyperglycemia	46
Cancer risk following low doses of ionising radiation – Current epidemiological evidence and implications for radiological protection	46
Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?	30
Pro-inflammatory response and genotoxicity caused by clay and graphene nanomaterials in A549 and THP-1 cells	21
N-acetyl-l-cysteine mediated regulation of DNA fragmentation, an apoptotic event, against methoxychlor toxicity in the granulosa cells of ovarian antral follicles	21
Cadmium selenide (CdSe) quantum dots cause genotoxicity and oxidative stress in Allium cepa plants	20
Crosstalk between different DNA repair pathways for DNA double strand break repairs	20
Mitomycin C induced genotoxic stress in endothelial cells is associated with differential expression of proinflammatory cytokines	20
Measurement of oxidatively damaged DNA in mammalian cells using the comet assay: Reflections on validity, reliability and variability	17
The 3D reconstructed skin micronucleus assay using imaging flow cytometry and deep learning: A proof-of-principle investigation	16
Establishment and multiparametric-cytogenetic validation of 60Co-gamma-ray induced, phospho-gamma-H2AX calibration curve for rapid biodosimetry and triage management during radiological emergencies	15
Gasoline-station workers in Brazil: Benzene exposure; Genotoxic and immunotoxic effects	14
Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks	14
Genotoxicity of selected pyrrolizidine alkaloids in human hepatoma cell lines HepG2 and Huh6	14
Differential effects of cisplatin combined with the flavonoid apigenin on HepG2, Hep3B, and Huh7 liver cancer cell lines	12
Alternariol monomethyl ether toxicity and genotoxicity in male Sprague-Dawley rats: 28-Day in vivo multi-endpoint assessment	12
Ionizing radiation, genotoxic stress, and mitochondrial DNA copy-number variation in Caenorhabditis elegans: droplet digital PCR analysis	12
Genotoxic effects of silver nanoparticles on a tropical marine amphipod via feeding exposure	11
Calibration of the comet assay using ionising radiation	11
Smoking, chromosomal aberrations, and cancer incidence in healthy subjects	10
Genomic instability in people living with HIV	10
Mode of action assessment of the genotoxic properties of antimony and its compounds evaluated in the ToxTracker assay	9
Genotoxicity of three mycotoxin contaminants of rice: 28-day multi-endpoint assessment in rats	9
Use of the alkaline comet assay for monitoring genotoxic effects of arsenic in human populations	8
Low dose radiation mechanisms: The certainty of uncertainty	8

Nanoplastics from ground polyethylene terephthalate food containers: Genotoxicity in human lung epithelial A549 cells	8
Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug-related metabolite, or drug-	8
Genetic damage in coal and uranium miners	8
Toxicity screening of air extracts representing different source sectors in the Greater Toronto and Hamilton areas: In vitro oxidative stress, pro-inflammatory response, and toxicogenomic analysis	8
In vitro genotoxicity assessment of graphene quantum dots nanoparticles: A metabolism-dependent response	8
Exposure to hypomethylating 5-aza-2′-deoxycytidine (decitabine) causes rapid, severe DNA damage, telomere elongation and mitotic dysfunction in human WIL2-NS cells	8
Evaluation of the genotoxic and cytotoxic effects of exposure to the herbicide 2,4-dichlorophenoxyacetic acid in Astyanax lacustris (Pisces, Characidae) and the potential for its removal from contamin	8
Consumption pattern and genotoxic potential of various smokeless tobacco products in Assam, India: A public health concern	7
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide	7
Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency	7
New insight into the antigenotoxic activity of Gentiana lutea extracts – Protective effect against food borne mutagens	7
Genomic instability evaluation by BMCyt and telomere length in Brazilian family farmers exposed to pesticides	7
Comparison of the transgenic rodent mutation assay, error corrected next generation duplex sequencing, and the alkaline comet assay to detect dose-related mutations following exposure to N-nitrosodiet	7
Mutagenicity of N-acyloxy-N-alkoxyamides as an indicator of DNA intercalation: The role of fluorene and fluorenone substituents as DNA intercalators	7
Blue light exposure enhances oxidative stress, causes DNA damage, and induces apoptosis signaling in B16F1 melanoma cells	7
Analysis of chromosomal aberrations and γH2A.X foci to identify radiation-sensitive ataxia-telangiectasia patients	7
Cytogenetic monitoring of peripheral blood lymphocytes from medical radiation professionals occupationally exposed to low-dose ionizing radiation	7
A panel of visual bacterial biosensors for the rapid detection of genotoxic and oxidative damage: A proof of concept study	7
Mechanism of reactive oxygen species generation and oxidative DNA damage induced by acrylohydroxamic acid, a putative metabolite of acrylamide	7
Short- and long-term reproducibility of the COMET assay for measuring DNA damage biomarkers in frozen blood samples of the EPIC-Heidelberg cohort	7
Evaluation of genotoxic damage in buccal mucosa cytome assays in Iraqi school children exposed to air pollutants emanating from oil fields	6
Synephrine and caffeine combination promotes cytotoxicity, DNA damage and transcriptional modulation of apoptosis-related genes in human HepG2 cells	6
D-10-camphorsulfonic acid: Safety evaluation	6
Ionizing radiation-induced genotoxic and oxidative damage in peripheral lymphocytes and plasma of healthy donors	6
Assessing phytotoxicity and cyto-genotoxicity of two insecticides using a battery of in-vitro biological assays	6
Shortened telomere length in peripheral blood leukocytes of patients with lung cancer, chronic obstructive pulmonary disease in a high indoor air pollution region in China	6
Exposure in the tobacco fields: Genetic damage and oxidative stress in tobacco farmers occupationally exposed during harvest and grading seasons	6
Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats	5
Emerging roles of DNA topoisomerases in the regulation of R-loops	5
Cytogenetic analysis of nuclear abnormalities in the erythrocytes of gecko lizards (Phyllopezus periosus) collected in a semi-arid region of northeast Brazil: Possible effects of natural background ra	5
Comprehensive review of genotoxicity data for diclofenac	5
Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence	5
Genotoxic effects of occupational exposure to glass fibres - A human biomonitoring study	5
Genotoxicity test battery – An assessment of its utility in early drug development	5
Genotoxicity assessment of root extracts of Paeonia lactiflora Pall	5
Dietary zinc deficient condition increases the Bisphenol A toxicity in diabetic rat testes	5
Women rag pickers at a dump in Ahmedabad: Genotoxicity and oxidative stress	5
In vitro toxicity and internalization of gold nanoparticles (AuNPs) in human epithelial colorectal adenocarcinoma (Caco-2) cells and the human skin keratinocyte (HaCaT) cells	5
Evaluation of soils under the influence of coal mining and a thermoelectric plant in the city of Candiota and vicinity, Brazil	5
Effects of isolated and combined exposures of Boana curupi (Anura: Hylidae) tadpoles to environmental doses of trichlorfon and ultraviolet radiation	5
Investigations on the new mechanism of action for acetaldehyde-induced clastogenic effects in human lung fibroblasts	5
Description and quantification of micronucleus and nuclear abnormalities in erythrocytes of the sentinel green turtle (Chelonia mydas) with fluorescence microscopy	4
Toxicity associated with long term use of aluminum cookware in mice: A systemic, genetic and reproductive perspective	4
DNA damage in dementia: Evidence from patients affected by severe Chronic Obstructive Pulmonary Disease (COPD) and meta-analysis of most recent literature	4
Molecular analysis of GPI-anchor biosynthesis pathway genes in rat strains used for the Pig-a gene mutation assay	4
Epigenetic effects of graphene oxide and its derivatives: A mini-review	4
A comparative study of persistent DNA oxidation and chromosomal instability induced in vitro by oxidizers and reference airborne particles	4
FTO regulates the DNA damage response via effects on cell-cycle progression	4
Association of telomere length with diabetes mellitus and idiopathic dilated cardiomyopathy in a South Indian population: A pilot study	4
Brazilian workers occupationally exposed to different toxic agents: A systematic review on DNA damage	4

Is telomere length in buccal or salivary cells a useful biomarker of exposure to air pollution? A review	4
Lack of mutagenicity of TiO2 nanoparticles in vitro despite cellular and nuclear uptake	4
Cytotoxicity and genotoxicity of blue LED light and protective effects of AA2G in mammalian cells and associated DNA repair deficient cell lines	4
Cytotoxic and genotoxic profiles of the pyrethroid insecticide lambda-cyhalothrin and its microformulation Karate® in CHO-K1 cells	4
Allium cepa tests: A plant-based tool for the early evaluation of toxicity and genotoxicity of newly synthetized antifungal molecules	4
Evaluation of the genotoxic and antigenotoxic effects of exopolysaccharide pullulan in human lymphocytes in vitro	4
Retrospective cytogenetic analysis of unstable and stable chromosome aberrations in the victims of radiation accident in Bulgaria	4
Prednisone is genotoxic in mice and Drosophila melanogaster	4
Radiosensitivity of radiotherapy patients: The effect of individual DNA repair capacity	4
Effects of dietary interventions on telomere dynamics	4
Transcription profiles in BEAS-2B cells exposed to organic extracts from particulate emissions produced by a port-fuel injection vehicle, fueled with conventional fossil gasoline and gasoline-ethanol	4
Histone deacetylase inhibitor 2-hexyl-4-pentynoic acid enhances hydroxyurea therapeutic effect in triple-negative breast cancer cells	4
Modulation of DNA damage by XPF, XPG and ERCC1 gene polymorphisms in pesticide-exposed agricultural workers of Punjab, North-West India	4
Assessment of the mutagenic potential of the water of an urban river by means of two Tradescantia-based test systems	4
Ex vivo/in vitro effects of aspirin and ibuprofen, bulk and nano forms, in peripheral lymphocytes of prostate cancer patients and healthy individuals	4
Cytokinesis-block micronucleus cytome (CBMN-CYT) assay and its relationship with genetic polymorphisms in welders	4
Maternal overnutrition before and during pregnancy induces DNA damage in male offspring: A rabbit model	4
In vitro genotoxic and mutagenic effects of water samples from Sapucaia and Esteio streams (Brazil) under the influence of different anthropogenic activities	3
A pooled analysis of molecular epidemiological studies on modulation of DNA repair by host factors	3
In silico prediction of the mutagenicity of nitroaromatic compounds using correlation weights of fragments of local symmetry	3
Relationship between DNA damage measured by the comet-assay and cognitive function	3
DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team	3
DNA damage in Brazilian newborns admitted to NICUs - association with maternal and neonatal outcomes	3
Cytogenetic follow-up of an individual after accidental exposure to industrial radiation using dicentric frequency in blood lymphocytes	3
Impact of genetic polymorphisms in kinetochore and spindle assembly genes on chromosomal aberration frequency in healthy humans	3
Inorganic elements in occupational settings: A review on the effects on telomere length and biology	3
Cytotoxicity and genotoxicity of tributyltin in the early embryonic chick, Gallus gallus domesticus	3
Mesenchymal stem cell-derived exosomes attenuate DNA damage response induced by cisplatin and bleomycin	3
Biomarkers of geno- and cytotoxicity in the native broad-snouted caiman (Caiman latirostris): Chromosomal aberrations and mitotic index	3
The comet assay for the evaluation of gut content genotoxicity: Use in human studies as an early biomarker of colon cancer risk	3
Pyrogenic synthetic amorphous silica (NM-203): Genotoxicity in rats following sub-chronic oral exposure	3
Genotoxic effect of meat consumption: A mini review	3
UVA causes specific mutagenic DNA damage through ROS production, rather than CPD formation, in Drosophila larvae	3
Chromosome aberration dynamics in breast cancer patients treated with radiotherapy: Implications for radiation biodosimetry	3
Analysis of ionizing radiation induced DNA damage response in human adult stem cells and differentiated neurons	3
Effects of foetal and breastfeeding exposure to methylmercury (MeHg) and retinol palmitate (Vitamin A) in rats: Redox parameters and susceptibility to DNA damage in liver	3
Medical personnel occupationally exposed to low-dose ionising radiation in Federation of Bosnia and Herzegovina: A cytogenetic study	3
Buccal micronucleus cytome assay in children living in an area with low anthropogenic pressure: The EFFE.BI.P. study	3
An investigation of DNA damage and DNA repair in chemical carcinogenesis triggered by small-molecule xenobiotics and in cancer: Thirty years with the comet assay	3
Low-dose ionizing radiation: Effects on the proliferation and migration of lens epithelial cells via activation of the Wnt/β-catenin pathway	3
Micronucleus assay of DNA damage among welders: Effects of welding processes	3
In vitro evaluation of chromosomal damage and DNA strand breaks after treatment with the poppy seed alkaloid thebaine	3
Cytotoxicity, genotoxicity, and immunohistochemical expression of p53 in the oral mucosal epithelium of adults following cone-beam computed tomography	3
The buccal micronucleus cytome assay: New horizons for its implementation in human studies	3
Genotoxicity and cytotoxicity of textile production effluents, before and after Bacillus subitilis bioremediation, in Astyanax lacustris (Pisces, Characidae)	3
DNA damage in cetaceans: A mini review	2
Non-clinical safety assessment of novel drug modalities: Genome safety perspectives on viral-, nuclease- and nucleotide-based gene therapies	2
Impact of the redox environment on propagation of radiation bystander effects: The modulating effect of oxidative metabolism and oxygen partial pressure	2
POT1 involved in telomeric DNA damage repair and genomic stability of cervical cancer cells in response to radiation	2
Persons chronically exposed to low doses of ionizing radiation: A cytogenetic dosimetry study	2
Hepatocyte proliferation activity in untreated rats, measured by immunohistochemical detection of Ki-67: The effect of age on the repeated-dose liver micronucleus assay	2
Evidence of genotoxicity, neurotoxicity, and antioxidant imbalance in silver catfish Rhamdia quelen after subchronic exposure to diisopentyl phthalate	2
Long-term effects of melatonin and resveratrol on aging rats: A multi-biomarker approach	2
Methylated and ethylated dialkylphosphate metabolites of organophosphate pesticides: DNA damage in bone marrow cells of Balb/c mice	2
Myricetin causes site-specific DNA damage via reactive oxygen species generation by redox interactions with copper ions	2
Liver-on-chip model and application in predictive genotoxicity and mutagenicity of drugs	2
Search for the optimal genotoxicity assay for routine testing of chemicals: Sensitivity and specificity of conventional and new test systems	2
Genotoxicity of ultraviolet light and sunlight in the bacterium Caulobacter crescentus: Wavelength-dependence	2
Potent mutagenicity of an azide, 3-azido-1,2-propanediol, in human TK6 cells	2
Fluorosilicic acid induces DNA damage and oxidative stress in bone marrow mesenchymal stem cells	2
Genotoxic effects of the ochratoxin A (OTA), its main metabolite (OTα) per se and in combination with fumonisin B1 in HepG2 cells and human lymphocytes	2
Myricetin protects natural killer cells from arsenite induced DNA damage by attenuating oxidative stress and retaining poly(ADP-Ribose) polymerase 1 activity	2
A comparison of cigarette smoke test matrices and their responsiveness in the mouse lymphoma assay: A case study	2
Application of land snail Helix lucorum for evaluation of genotoxicity of soil pollution	2
Flash-comet: Significantly improved speed and sensitivity of the comet assay through the introduction of lithium-based solutions and a more gentle lysis	2
Hydrogen inhalation: in vivo rat genotoxicity tests	2
No evidence for genotoxicity in mice due to exposure to intermediate-frequency magnetic fields used for wireless power-transfer systems	2
Transgenerational effects of gamma radiation dose and dose rate on Drosophila flies irradiated at an early embryonal stage	2
Toxicogenetic assessment of a pre-workout supplement: In vitro mutagenicity, cytotoxicity, genotoxicity and glutathione determination in liver cell lines and in silico ADMET approaches	2
Differentiating between micronucleus dose-responses induced by whole cigarette smoke solutions with Benchmark Dose potency ranking	2
Letter to the editor	2
Mycobacterium tuberculosis infection and cytogenetic abnormalities among people with HIV	2
Metabolic activation enhances the cytotoxicity, genotoxicity and mutagenicity of two synthetic alkaloids with selective effects against human tumour cell lines	2
Diosgenin increases BBC3 expression in HepG2/C3A cells and alters cell communication in a 3D spheroid model	2
TK6 genome profile compared with WIL2-NS: Reference data to improve the reproducibility of genotoxicity studies	2
Septilin: A versatile anticlastogenic, antigenotoxic, antioxidant and histoprotective herbo-mineral formulation on cisplatin-induced toxicity in mice	2
Quantifying telomere transcripts as tool to improve risk assessment for genetic instability and genotoxicity	2
Pyrene-polyethylene glycol-modified multi-walled carbon nanotubes: Genotoxicity in V79-4 fibroblast cells	2
Lymphocyte DNA damage in sepsis and septic-shock intensive-care patients: Damage is greater in non-intubated patients	2
Oxidative stress and DNA damage in critically ill patients with sepsis	2

Chronic human exposure to ionizing radiation: Individual variability of chromosomal aberration frequencies and G0 radiosensitivities	2
Auto repair workers exposed to PM2.5 particulate matter in Barranquilla, Colombia: Telomere length and hematological parameters	2
Links between telomere dysfunction and hallmarks of aging	2
Alteration of genome-wide DNA methylation in non-uranium miners induced by high level radon exposure	2
Evaluation of telomere length and genotoxicity among asphalt associated workers	2
Genotoxicity and apoptotic effect of silver(I) complexes with mixed-ligands of thiosemicarbazones and diphenyl(p-tolyl)phosphine on malignant melanoma cells, SK-MEL-28	2
Exploring cytokinesis block micronucleus assay in Croatia: A journey through the past, present, and future in biomonitoring of the general population	2
Biological and cellular responses of humans to high-level natural radiation: A clarion call for a fresh perspective on the linear no-threshold paradigm	2
Genotoxic risk assessment of solar UV radiation in tadpoles from Brazilian wetlands	2
The evaluation of the efficacy and potential genotoxic hazard of combined SAHA and 5-FU treatment in the chemoresistant colorectal cancer cell lines	2
The impact of preconceptional exposure of F0 male mice to bisphenol A alone or in combination with X-rays on the intrauterine development of F2 progeny	2
The calculation of historical control limits in toxicology: Do's, don'ts and open issues from a statistical perspective	2
Potential radioprotective properties of arbutin against ionising radiation on human leukocytes in vitro	2