Mutation Research-Genetic Toxicology and Environmental Mutagenesis

Article	Citations
Cancer risk following low doses of ionising radiation – Current epidemiological evidence and implications for radiological protection	33
Mechanisms underlying the pathophysiology of type 2 diabetes: From risk factors to oxidative stress, metabolic dysfunction, and hyperglycemia	32
Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?	20
N-acetyl-l-cysteine mediated regulation of DNA fragmentation, an apoptotic event, against methoxychlor toxicity in the granulosa cells of ovarian antral follicles	19
Mitomycin C induced genotoxic stress in endothelial cells is associated with differential expression of proinflammatory cytokines	18
Key read across framework components and biology based improvements	18
Measurement of oxidatively damaged DNA in mammalian cells using the comet assay: Reflections on validity, reliability and variability	17
Pro-inflammatory response and genotoxicity caused by clay and graphene nanomaterials in A549 and THP-1 cells	17
Crosstalk between different DNA repair pathways for DNA double strand break repairs	17
EURL ECVAM Genotoxicity and Carcinogenicity Database of Substances Eliciting Negative Results in the Ames Test: Construction of the Database	15
Strategies in genotoxicology: Acceptance of innovative scientific methods in a regulatory context and from an industrial perspective	15
Genotoxicity of selected pyrrolizidine alkaloids in human hepatoma cell lines HepG2 and Huh6	14
Establishment and multiparametric-cytogenetic validation of 60Co-gamma-ray induced, phospho-gamma-H2AX calibration curve for rapid biodosimetry and triage management during radiological emergencies	14
Genotoxic and cytotoxic properties of two medical plants (Teucrium arduini L.and Teucrium flavum L.) in relation to their polyphenolic contents	14
Genotoxicity and cellular uptake of nanosized and fine copper oxide particles in human bronchial epithelial cells in vitro	13
Cadmium selenide (CdSe) quantum dots cause genotoxicity and oxidative stress in Allium cepa plants	13
The 3D reconstructed skin micronucleus assay using imaging flow cytometry and deep learning: A proof-of-principle investigation	12
Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks	12
TiO2 genotoxicity: An update of the results published over the last six years	12
Differential effects of cisplatin combined with the flavonoid apigenin on HepG2, Hep3B, and Huh7 liver cancer cell lines	12
Gasoline-station workers in Brazil: Benzene exposure; Genotoxic and immunotoxic effects	11
Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase	11
Influence of bariatric surgery induced weight loss on oxidative DNA damage	11
Loci associated with genomic damage levels in chronic kidney disease patients and controls	9
Smoking, chromosomal aberrations, and cancer incidence in healthy subjects	9

Genotoxicity of three mycotoxin contaminants of rice: 28-day multi-endpoint assessment in rats	9
Ionizing radiation, genotoxic stress, and mitochondrial DNA copy-number variation in Caenorhabditis elegans: droplet digital PCR analysis	9
Calibration of the comet assay using ionising radiation	9
Induction of genotoxicity and mutagenic potential of heavy metals in Thai occupational workers	9
Genotoxicant exposure, activation of the aryl hydrocarbon receptor, and lipid peroxidation in cultured human alveolar type II A549 cells	9
Alternariol monomethyl ether toxicity and genotoxicity in male Sprague-Dawley rats: 28-Day in vivo multi-endpoint assessment	8
Genomic instability in people living with HIV	8
Mechanism of reactive oxygen species generation and oxidative DNA damage induced by acrylohydroxamic acid, a putative metabolite of acrylamide	7
Mode of action assessment of the genotoxic properties of antimony and its compounds evaluated in the ToxTracker assay	7
2-Methylfuran: Toxicity and genotoxicity in male Sprague-Dawley rats	7
New insight into the antigenotoxic activity of Gentiana lutea extracts – Protective effect against food borne mutagens	7
Increased micronucleus frequencies in reticulocytes of children exposed to industrial pollution: oxidative stress and the OGG1 S326C polymorphism	7
Genetic damage in coal and uranium miners	7
Use of the alkaline comet assay for monitoring genotoxic effects of arsenic in human populations	6
D-10-camphorsulfonic acid: Safety evaluation	6
Genotoxic effects of silver nanoparticles on a tropical marine amphipod via feeding exposure	6
Genotoxicity studies with an ethanolic extract of Kalanchoe pinnata leaves	6
Consumption pattern and genotoxic potential of various smokeless tobacco products in Assam, India: A public health concern	6
Exposure of patients to low doses of X-radiation during neuro-interventional imaging and procedures: Dose estimation and analysis of γ-H2AX foci and gene expression in blood lymphocytes	6
Mutagenicity of N-acyloxy-N-alkoxyamides as an indicator of DNA intercalation: The role of fluorene and fluorenone substituents as DNA intercalators	6
Evaluation of genotoxic damage in buccal mucosa cytome assays in Iraqi school children exposed to air pollutants emanating from oil fields	6
Cytogenetic monitoring of peripheral blood lymphocytes from medical radiation professionals occupationally exposed to low-dose ionizing radiation	6
Genotoxicity of the organophosphate pesticide malathion and its metabolite dimethylthiophosphate in human cells in vitro	6
Shortened telomere length in peripheral blood leukocytes of patients with lung cancer, chronic obstructive pulmonary disease in a high indoor air pollution region in China	5
Exposure to hypomethylating 5-aza-2′-deoxycytidine (decitabine) causes rapid, severe DNA damage, telomere elongation and mitotic dysfunction in human WIL2-NS cells	5
Toxicity screening of air extracts representing different source sectors in the Greater Toronto and Hamilton areas: In vitro oxidative stress, pro-inflammatory response, and toxicogenomic analysis	5
Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence	5
High homocysteine promotes telomere dysfunction and chromosomal instability in human neuroblastoma SH-SY5Y cells	5
Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug-related metabolite, or drug-	5
Repurposing sodium diclofenac as a radiation countermeasure agent: A cytogenetic study in human peripheral blood lymphocytes	5
Effects of sulforaphane on the oxidative response, apoptosis, and the transcriptional profile of human stomach mucosa cells in vitro	5
Investigations on the new mechanism of action for acetaldehyde-induced clastogenic effects in human lung fibroblasts	5
Synephrine and caffeine combination promotes cytotoxicity, DNA damage and transcriptional modulation of apoptosis-related genes in human HepG2 cells	5
Low dose radiation mechanisms: The certainty of uncertainty	5
Short- and long-term reproducibility of the COMET assay for measuring DNA damage biomarkers in frozen blood samples of the EPIC-Heidelberg cohort	5
Benchmark dose analyses of γH2AX and pH3 endpoints for quantitative comparison of in vitro genotoxicity potential of lipophilic phycotoxins	5
Emerging roles of DNA topoisomerases in the regulation of R-loops	5
Maternal overnutrition before and during pregnancy induces DNA damage in male offspring: A rabbit model	4
Retrospective cytogenetic analysis of unstable and stable chromosome aberrations in the victims of radiation accident in Bulgaria	4
Ionizing radiation-induced genotoxic and oxidative damage in peripheral lymphocytes and plasma of healthy donors	4
Comprehensive review of genotoxicity data for diclofenac	4
Molecular analysis of GPI-anchor biosynthesis pathway genes in rat strains used for the Pig-a gene mutation assay	4
Evaluation of the genotoxic and cytotoxic effects of exposure to the herbicide 2,4-dichlorophenoxyacetic acid in Astyanax lacustris (Pisces, Characidae) and the potential for its removal from contamin	4
In vitro genotoxicity assessment of graphene quantum dots nanoparticles: A metabolism-dependent response	4
Women rag pickers at a dump in Ahmedabad: Genotoxicity and oxidative stress	4
Genotoxicity test battery – An assessment of its utility in early drug development	4
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide	4
Cytotoxicity and genotoxicity of blue LED light and protective effects of AA2G in mammalian cells and associated DNA repair deficient cell lines	4
Epigenetic effects of graphene oxide and its derivatives: A mini-review	4
Genomic instability evaluation by BMCyt and telomere length in Brazilian family farmers exposed to pesticides	4

In vitro toxicity and internalization of gold nanoparticles (AuNPs) in human epithelial colorectal adenocarcinoma (Caco-2) cells and the human skin keratinocyte (HaCaT) cells	4
Brazilian workers occupationally exposed to different toxic agents: A systematic review on DNA damage	4
Evaluation of the genotoxic potential of apoptosis inducers with the γH2AX assay in human cells	4
Effects of isolated and combined exposures of Boana curupi (Anura: Hylidae) tadpoles to environmental doses of trichlorfon and ultraviolet radiation	4
Analysis of chromosomal aberrations and γH2A.X foci to identify radiation-sensitive ataxia-telangiectasia patients	4
Ex vivo/in vitro effects of aspirin and ibuprofen, bulk and nano forms, in peripheral lymphocytes of prostate cancer patients and healthy individuals	4
Guidance for publishing comet assay results	4
Lack of mutagenicity of TiO2 nanoparticles in vitro despite cellular and nuclear uptake	3
Modulation of DNA damage by XPF, XPG and ERCC1 gene polymorphisms in pesticide-exposed agricultural workers of Punjab, North-West India	3
Chromosome aberration dynamics in breast cancer patients treated with radiotherapy: Implications for radiation biodosimetry	3
DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team	3
Cytokinesis-block micronucleus cytome (CBMN-CYT) assay and its relationship with genetic polymorphisms in welders	3
Comparison of the transgenic rodent mutation assay, error corrected next generation duplex sequencing, and the alkaline comet assay to detect dose-related mutations following exposure to N-nitrosodiet	3
In vitro genotoxic and mutagenic effects of water samples from Sapucaia and Esteio streams (Brazil) under the influence of different anthropogenic activities	3
Induction of the SOS response of Escherichia coli in repair-defective strains by several genotoxic agents	3
Evaluation of the genotoxic and antigenotoxic effects of exopolysaccharide pullulan in human lymphocytes in vitro	3
Toxicity associated with long term use of aluminum cookware in mice: A systemic, genetic and reproductive perspective	3
DNA damage measured in blood cells predicts overall and progression-free survival in germ cell tumour patients	3
Inorganic elements in occupational settings: A review on the effects on telomere length and biology	3
Genotoxic effect of meat consumption: A mini review	3
Association of telomere length with diabetes mellitus and idiopathic dilated cardiomyopathy in a South Indian population: A pilot study	3
Biomarkers of geno- and cytotoxicity in the native broad-snouted caiman (Caiman latirostris): Chromosomal aberrations and mitotic index	3
Buccal micronucleus cytome assay in children living in an area with low anthropogenic pressure: The EFFE.BI.P. study	3
DNA damage in dementia: Evidence from patients affected by severe Chronic Obstructive Pulmonary Disease (COPD) and meta-analysis of most recent literature	3
Assessment of the mutagenic potential of the water of an urban river by means of two Tradescantia-based test systems	3
Cardiac catheterization procedures in children with congenital heart disease: Increased chromosomal aberrations in peripheral lymphocytes	3
Summary of major conclusions from the 7th International Workshop on Genotoxicity Testing (IWGT), Tokyo, Japan	3
Cytotoxicity, genotoxicity, and immunohistochemical expression of p53 in the oral mucosal epithelium of adults following cone-beam computed tomography	3
Cytogenetic follow-up of an individual after accidental exposure to industrial radiation using dicentric frequency in blood lymphocytes	3
Effects of foetal and breastfeeding exposure to methylmercury (MeHg) and retinol palmitate (Vitamin A) in rats: Redox parameters and susceptibility to DNA damage in liver	3
Evaluation of soils under the influence of coal mining and a thermoelectric plant in the city of Candiota and vicinity, Brazil	3
Transcription profiles in BEAS-2B cells exposed to organic extracts from particulate emissions produced by a port-fuel injection vehicle, fueled with conventional fossil gasoline and gasoline-ethanol	3
Exposure in the tobacco fields: Genetic damage and oxidative stress in tobacco farmers occupationally exposed during harvest and grading seasons	2
Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency	2
Letter to the editor	2
Radiosensitivity of radiotherapy patients: The effect of individual DNA repair capacity	2
No evidence for genotoxicity in mice due to exposure to intermediate-frequency magnetic fields used for wireless power-transfer systems	2
Genotoxic risk assessment of solar UV radiation in tadpoles from Brazilian wetlands	2
FTO regulates the DNA damage response via effects on cell-cycle progression	2
Cytogenetic analysis of nuclear abnormalities in the erythrocytes of gecko lizards (Phyllopezus periosus) collected in a semi-arid region of northeast Brazil: Possible effects of natural background ra	2
Prednisone is genotoxic in mice and Drosophila melanogaster	2
Medical personnel occupationally exposed to low-dose ionising radiation in Federation of Bosnia and Herzegovina: A cytogenetic study	2
DNA damage in Brazilian newborns admitted to NICUs - association with maternal and neonatal outcomes	2
Genotoxic effects of the ochratoxin A (OTA), its main metabolite (OTα) per se and in combination with fumonisin B1 in HepG2 cells and human lymphocytes	2
TK6 genome profile compared with WIL2-NS: Reference data to improve the reproducibility of genotoxicity studies	2
Diosgenin increases BBC3 expression in HepG2/C3A cells and alters cell communication in a 3D spheroid model	2
An experimental aerosol air–agar interface mouse lymphoma assay methodology	2
Blue light exposure enhances oxidative stress, causes DNA damage, and induces apoptosis signaling in B16F1 melanoma cells	2
A panel of visual bacterial biosensors for the rapid detection of genotoxic and oxidative damage: A proof of concept study	2
Flash-comet: Significantly improved speed and sensitivity of the comet assay through the introduction of lithium-based solutions and a more gentle lysis	2
Low-dose ionizing radiation: Effects on the proliferation and migration of lens epithelial cells via activation of the Wnt/β-catenin pathway	2
Differentiating between micronucleus dose-responses induced by whole cigarette smoke solutions with Benchmark Dose potency ranking	2
A comparative study of persistent DNA oxidation and chromosomal instability induced in vitro by oxidizers and reference airborne particles	2
Potential radioprotective properties of arbutin against ionising radiation on human leukocytes in vitro	2
Analysis of ionizing radiation induced DNA damage response in human adult stem cells and differentiated neurons	2
Septilin: A versatile anticlastogenic, antigenotoxic, antioxidant and histoprotective herbo-mineral formulation on cisplatin-induced toxicity in mice	2
Metabolic activation enhances the cytotoxicity, genotoxicity and mutagenicity of two synthetic alkaloids with selective effects against human tumour cell lines	2
A pooled analysis of molecular epidemiological studies on modulation of DNA repair by host factors	2
In vitro evaluation of chromosomal damage and DNA strand breaks after treatment with the poppy seed alkaloid thebaine	2
Is telomere length in buccal or salivary cells a useful biomarker of exposure to air pollution? A review	2
Pyrene-polyethylene glycol-modified multi-walled carbon nanotubes: Genotoxicity in V79-4 fibroblast cells	2
Lymphocyte DNA damage in sepsis and septic-shock intensive-care patients: Damage is greater in non-intubated patients	2
Application of land snail Helix lucorum for evaluation of genotoxicity of soil pollution	2
The comet assay for the evaluation of gut content genotoxicity: Use in human studies as an early biomarker of colon cancer risk	2
Allium cepa tests: A plant-based tool for the early evaluation of toxicity and genotoxicity of newly synthetized antifungal molecules	2
Cytotoxicity and genotoxicity of tributyltin in the early embryonic chick, Gallus gallus domesticus	2
An investigation of DNA damage and DNA repair in chemical carcinogenesis triggered by small-molecule xenobiotics and in cancer: Thirty years with the comet assay	2
Evaluation of telomere length and genotoxicity among asphalt associated workers	2
Dietary zinc deficient condition increases the Bisphenol A toxicity in diabetic rat testes	2
Effects of dietary interventions on telomere dynamics	2
The evaluation of the efficacy and potential genotoxic hazard of combined SAHA and 5-FU treatment in the chemoresistant colorectal cancer cell lines	2
Mycobacterium tuberculosis infection and cytogenetic abnormalities among people with HIV	2
Impact of genetic polymorphisms in kinetochore and spindle assembly genes on chromosomal aberration frequency in healthy humans	2
Search for the optimal genotoxicity assay for routine testing of chemicals: Sensitivity and specificity of conventional and new test systems	2
Fluorosilicic acid induces DNA damage and oxidative stress in bone marrow mesenchymal stem cells	2
The Iberian legacy into a young genetic xeroderma pigmentosum cluster in central Brazil	2
DNA damage in cetaceans: A mini review	2
Histone deacetylase inhibitor 2-hexyl-4-pentynoic acid enhances hydroxyurea therapeutic effect in triple-negative breast cancer cells	2
UVA causes specific mutagenic DNA damage through ROS production, rather than CPD formation, in Drosophila larvae	1
Links between telomere dysfunction and hallmarks of aging	1

POT1 involved in telomeric DNA damage repair and genomic stability of cervical cancer cells in response to radiation	1
The buccal micronucleus cytome assay: New horizons for its implementation in human studies	1
Hepatocyte proliferation activity in untreated rats, measured by immunohistochemical detection of Ki-67: The effect of age on the repeated-dose liver micronucleus assay	1
Experimental investigations of carcinogen-induced mutation spectra: Innovation, challenges and future directions	1
Mesenchymal stem cell-derived exosomes attenuate DNA damage response induced by cisplatin and bleomycin	1
Cell line-dependent difference in glutathione levels affects the cigarette sidestream smoke-induced inhibition of nucleotide excision repair	1
The role of BRCA2 in the fragility of interstitial telomeric sites	1
Could alder buckthorn (Frangula alnus Mill) be a source of chemotherapeutics effective against hepato- and colorectal carcinoma? An in vitro study	1
The moderating role of macronutrient intake in relation to body composition and genotoxicity: A study with gym users	1
Evidence of genotoxicity, neurotoxicity, and antioxidant imbalance in silver catfish Rhamdia quelen after subchronic exposure to diisopentyl phthalate	1
Occupational exposure of dental technicians to methyl methacrylate: Genotoxicity assessment	1
Re-evaluation of CBMN test reference values of persons continuously occupationally exposed to low doses of ionizing radiation in Serbia	1
Myricetin protects natural killer cells from arsenite induced DNA damage by attenuating oxidative stress and retaining poly(ADP-Ribose) polymerase 1 activity	1
Pyrogenic synthetic amorphous silica (NM-203): Genotoxicity in rats following sub-chronic oral exposure	1
Potassium bromate-induced oxidative stress, genotoxicity and cytotoxicity in the blood and liver cells of mice	1
“Statistical significance” and other important considerations in genotoxicity safety testing	1
Auto repair workers exposed to PM2.5 particulate matter in Barranquilla, Colombia: Telomere length and hematological parameters	1
Toxicogenetic assessment of a pre-workout supplement: In vitro mutagenicity, cytotoxicity, genotoxicity and glutathione determination in liver cell lines and in silico ADMET approaches	1
Long-term effects of melatonin and resveratrol on aging rats: A multi-biomarker approach	1
The calculation of historical control limits in toxicology: Do's, don'ts and open issues from a statistical perspective	1
Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats	1
Chronic human exposure to ionizing radiation: Individual variability of chromosomal aberration frequencies and G0 radiosensitivities	1
DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay	1
Assessing phytotoxicity and cyto-genotoxicity of two insecticides using a battery of in-vitro biological assays	1
In vitro and in vivo genotoxicity assessment of ferric ferrocyanide and potassium-cobalt ferrocyanide	1
Myricetin causes site-specific DNA damage via reactive oxygen species generation by redox interactions with copper ions	1
The impact of preconceptional exposure of F0 male mice to bisphenol A alone or in combination with X-rays on the intrauterine development of F2 progeny	1
Assays of genotoxic damage in peripheral blood lymphocytes of individuals occupationally exposed to different x-ray systems in hospital radiology departments	1
The MAP kinase inhibitor PD98059 reduces chromosomal instability in the autoimmune encephalomyelitis SJL/J-mouse model of multiple sclerosis	1
DNA damage, repair and the improvement of cancer therapy – A tribute to the life and research of Barbara Tudek	1
Genotoxicity and apoptotic effect of silver(I) complexes with mixed-ligands of thiosemicarbazones and diphenyl(p-tolyl)phosphine on malignant melanoma cells, SK-MEL-28	1
Genomic instability in peripheral blood lymphocytes of patients diagnosed with high-grade squamous intraepithelial lesions: CIN 2 versus CIN 3	1
A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo	1
A comparison of cigarette smoke test matrices and their responsiveness in the mouse lymphoma assay: A case study	1
Biological and cellular responses of humans to high-level natural radiation: A clarion call for a fresh perspective on the linear no-threshold paradigm	1
Impact of the redox environment on propagation of radiation bystander effects: The modulating effect of oxidative metabolism and oxygen partial pressure	1
Effects of antioxidant capacity on micronucleus induction by cigarette smoke in mammalian cells	1
Translocation dose-response curve for 137Cs γ-rays: Dose validation at various dose rate and changing dose rate conditions	1
Transgenerational effects of gamma radiation dose and dose rate on Drosophila flies irradiated at an early embryonal stage	1
Evaluation and interpretation of cytogenetic test results based on biological relevance	1
Nanoplastics from ground polyethylene terephthalate food containers: Genotoxicity in human lung epithelial A549 cells	1
Genotoxicity and cytotoxicity of textile production effluents, before and after Bacillus subitilis bioremediation, in Astyanax lacustris (Pisces, Characidae)	1
Corrigendum to “Flash-comet: Significantly improved speed and sensitivity of the comet assay through the introduction of lithium-based solutions and a more gentle lysis” [Mutat. Res. – Genet. Toxicol.	1
Cytogenetic analysis (buccal micronucleus cytome assay) of radioactive waste management workers	1
Low extracellular pH inhibits nucleotide excision repair	1
Genotoxicity assessment of root extracts of Paeonia lactiflora Pall	1
Potent mutagenicity of an azide, 3-azido-1,2-propanediol, in human TK6 cells	1
CYP1B1 converts procarcinogens into genotoxins in Saccharomyces cerevisiae	1
Micronuclei in embryos of eight seabird species in northwestern Mexico: A biomarker of exposure to coastal pollution?	1
DNA double-strand break repair and adaptive responses of low-dose radiation in normal and tumor lung cell lines	1
Expression of miR-34a is a sensitive biomarker for exposure to genotoxic agents in human lymphoblastoid TK6 cells	1
Relationship between DNA damage measured by the comet-assay and cognitive function	1
Effects of radiation quality and dose rate on radiation-induced nucleoplasmic bridges in human peripheral blood lymphocytes	1
Methylated and ethylated dialkylphosphate metabolites of organophosphate pesticides: DNA damage in bone marrow cells of Balb/c mice	1
Genotoxicity of surface waters in Brazil	1
Assessment of the miniaturized liquid Ames microplate format (MPF™) for a selection of the test items from the recommended list of genotoxic and non-genotoxic chemicals	1
Aneugenic and clastogenic alterations in the DBA/IJ mouse model of rheumatoid arthritis treated with rituximab, an anti-CD20 antibody	1
Micronucleus assay of DNA damage among welders: Effects of welding processes	1