OOIR: Observatory of International Research

Papers

(The median citation count of Mutation Research-Genetic Toxicology and Environmental Mutagenesis is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
The dose-, LET-, and gene-dependent patterns of intragenic DNA changes underlying recessive visible mutations at the autosomal gene cinnabar of Drosophila melanogaster	67
Dynamic subcellular localization of HMGB1 in colorectal cancer cells following exposure to environmental mutagens	41
Analysis of ionizing radiation induced DNA damage response in human adult stem cells and differentiated neurons	30
FTO regulates the DNA damage response via effects on cell-cycle progression	27
Analysis of the trends in in vitro studies of the Latin America-Comet assay (LA-COMET) Group	23
Arsenite: Toxicity and genotoxicity in a mouse Leydig cell line	20
Investigation of genotoxicity induced by intermediate frequency magnetic field combined with ionizing radiation: In vitro study on human fibroblast cells	20
Helicobacter pylori plus N-Methyl-N′-nitro-N-nitrosoguanidine: DNA damage and repair: Malignant transformation of human esophageal epithelial cells	18
Micro- and Nanoplastics as Vectors of Aquatic Pollutants and Genotoxicity: An Integrated Review Across Aquatic and Mammalian Systems with Special Reference to the Scenario in India	18
Relationship between DNA damage measured by the comet-assay and cognitive function	17
Evidence of genotoxicity, neurotoxicity, and antioxidant imbalance in silver catfish Rhamdia quelen after subchronic exposure to diisopentyl phthalate	17
The probable reasons of arsenic susceptibility in a chronically exposed population of West Bengal	17
Mutagenic effects of a commercial glyphosate-based herbicide formulation on the soil filamentous fungus Aspergillus nidulans depending on the mode of exposure	16
Low-dose ionizing radiation: Effects on the proliferation and migration of lens epithelial cells via activation of the Wnt/β-catenin pathway	16
An evaluation of common pharmaceutical solvents in the in vitro micronucleus assay	16
Expression of concern: “6-Hydroxydopamine and lipopolysaccharides induced DNA damage in astrocytes: Involvement of nitric oxide and mitochondria” [Mutat. Res. Genet. Toxicol. Environ. Mutagen. (2015)	16
Epistatic interactions in DNA repair genes as biomarkers of susceptibility for DNA damage in pesticide-exposed agricultural workers of Punjab, North-West India	15
Oxidative stress and DNA damage in critically ill patients with sepsis	15
Saxagliptin, a selective dipeptidyl peptidase-4 inhibitor, alleviates somatic cell aneugenicity and clastogenicity in diabetic mice	14
Editorial Board	14
Cytogenetic markers in newborns of mothers with comorbidities	13
Acute and chronic post-COVID-19 conditions: A study of genetic integrity and clinical markers	12
Aminated polystyrene and DNA strand breaks in A549, Caco-2, THP-1 and U937 human cell lines	11
In silico prediction of the mutagenicity of nitroaromatic compounds using correlation weights of fragments of local symmetry	11
Toxicity and genotoxicity of AlCl3 in transgenic Drosophila melanogaster (hsp-70 lacZ) Bg	11

Editorial Board	10
Diosgenin increases BBC3 expression in HepG2/C3A cells and alters cell communication in a 3D spheroid model	10
Genotoxic and cytotoxic effects of dietary patterns and lifestyle factors: A cross-sectional comparison of Brazilian and Spanish gym users	10
Is telomere length in buccal or salivary cells a useful biomarker of exposure to air pollution? A review	10
A Special Issue honoring Prof. Michael Fenech	10
Occupational exposure to radiation among health workers: Genome integrity and predictors of exposure	10
Fibroblast-based radiosensitivity assays as a clinically valuable tool for (severe) combined immunodeficiency syndromes	10
Editorial Board	10
Mycobacterium tuberculosis infection and cytogenetic abnormalities among people with HIV	10
Lymphocyte DNA damage in sepsis and septic-shock intensive-care patients: Damage is greater in non-intubated patients	10
In vivo evaluation of cisplatin(IV) conjugated to iron oxide adipate/tartrate nanoparticles using Drosophila melanogaster	9
Exploring cytokinesis block micronucleus assay in Croatia: A journey through the past, present, and future in biomonitoring of the general population	9
Bleomycin induces short-term telomere fragility in Epstein-Barr virus-transformed human lymphoblastoid cells	9
Perchloroethylene: Genotoxicity and cytotoxicity in human peripheral blood lymphocytes in vitro	9
Comparison of the transgenic rodent mutation assay, error corrected next generation duplex sequencing, and the alkaline comet assay to detect dose-related mutations following exposure to N-nitrosodiet	9
Genotoxicity and the stability of N-nitrosomorpholine activity following UVA irradiation	9
Genotoxic effects of silver nanoparticles on a tropical marine amphipod via feeding exposure	9
Response to "Letter to the Editor; Re. Emiroğlu and Çeli̇k, “Radiology personnel chronically exposed to low-dose ionizing radiation: Assessment of genotoxic damage with the buccal micronucleus cytome	8
Limited concordance between micronucleus and chromosomal aberration assays in medical radiation workers: Evidence from a tertiary hospital-based study	8
Chromosome-specific induction of micronuclei and chromosomal aberrations by mitomycin C: Involvement of human chromosomes 9, 1 and 16	8
Editorial Board	8
Genotoxic effects of occupational exposure to glass fibres - A human biomonitoring study	8
Chromosome length ratio as a biomarker of DNA damage in cells exposed to high dose ionizing radiation	8
The transgenic MutaMouse hepatocyte mutation assay in vitro: Mutagenicity and mutation spectra of six substances with different mutagenic mechanisms	8
Brazil nut consumption reduces DNA damage in overweight type 2 diabetes mellitus patients	8
Transgenerational effects of gamma radiation dose and dose rate on Drosophila flies irradiated at an early embryonal stage	8
Whole-genome high-fidelity sequencing: A novel approach to detecting and characterization of mutagenicity in vivo	8
Biological and cellular responses of humans to high-level natural radiation: A clarion call for a fresh perspective on the linear no-threshold paradigm	7
Chromosome malsegregation induced by methanol in Drosophila melanogaster females	7
In vitro genotoxicity assessment of graphene quantum dots nanoparticles: A metabolism-dependent response	7
Paraoxon and glyphosate induce DNA double-strand breaks but are not type II topoisomerase poisons	7
Obituary	7
Alteration of genome-wide DNA methylation in non-uranium miners induced by high level radon exposure	7
DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay	7
Oxidative DNA damage: Induction by fructose, in vitro, and its enhancement by hydrogen peroxide	7
Micronuclei and other nuclear anomalies in exfoliated urothelial cells and urinary 8-hydroxy-deoxyguanosine levels among Turkish hairdressers	7
“Statistical significance” and other important considerations in genotoxicity safety testing	7
DNA double-strand break repair and adaptive responses of low-dose radiation in normal and tumor lung cell lines	7
Letter to the Editor; Re. Emiroğlu and Çeli̇k, “Radiology personnel chronically exposed to low-dose ionizing radiation: Assessment of genotoxic damage with the buccal micronucleus cytome assay”	7
Nanoplastics from ground polyethylene terephthalate food containers: Genotoxicity in human lung epithelial A549 cells	7
Genetic instability in farmers using pesticides: A study in Brazil with analysis combining alkaline comet and micronucleus assays	6
Allium cepa tests: A plant-based tool for the early evaluation of toxicity and genotoxicity of newly synthetized antifungal molecules	6
Constitutional chromosomal anomalies in children, fetal alcohol syndrome, and maternal toxicant exposures: A longitudinal cohort study	6
Genotoxicity and cytotoxicity assessment of 'forever chemicals' in zebrafish (Danio rerio)	6
Toxicogenetic assessment of a pre-workout supplement: In vitro mutagenicity, cytotoxicity, genotoxicity and glutathione determination in liver cell lines and in silico ADMET approaches	6
Genotoxicity assessments of N-nitrosoethylisopropylamine (NEIPA) and N-nitrosodiisopropylamine (NDIPA) in the C57BL/6J mouse	6
POT1 involved in telomeric DNA damage repair and genomic stability of cervical cancer cells in response to radiation	6
Evaluation and interpretation of cytogenetic test results based on biological relevance	6
Alkaline comet assay in human biomonitoring studies by the Latin America / LA-COMET group	6
Use of peptide nucleic acid probe to determine telomere dynamics in improving chromosome analysis in genetic toxicology studies	6

Assessment of radiation doses and DNA damage in pediatric patients undergoing interventional procedures for vascular anomalies	6
Influence of genetic polymorphisms of Hg metabolism and DNA repair on the frequencies of micronuclei, nucleoplasmic bridges, and nuclear buds in communities living in gold mining areas	6
Human aldo-keto reductases (AKR1C1-AKR1C3) increase the mutagenicity of environmental nitroarenes in the mammalian HPRT forward gene mutagenicity assay	5
Biography of Andrew Collins	5
Bleomycin-induced chromosomal aberrations in Epstein-Barr virus-transformed human lymphoblastoid cells	5
Relative mutagenic effectiveness and efficiency of chemical mutagens (Caffeine and EMS) and heavy metals [(Pb(NO3)2 and Cd(NO3)2)] in developing chlorophyll and morphological mutants in lentil	5
Lack of mutagenicity of TiO2 nanoparticles in vitro despite cellular and nuclear uptake	5
Editorial Board	5
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide	5
Multi-endpoint in vitro toxicological assessment of snus and tobacco-free nicotine pouch extracts	5
Potassium bromate-induced oxidative stress, genotoxicity and cytotoxicity in the blood and liver cells of mice	5
In memoriam – Professor Diana Anderson (1940–2024)	5
Reducing risk of false positives in the in vivo comet assay and improving result reliability	5
Medical personnel occupationally exposed to low-dose ionising radiation in Federation of Bosnia and Herzegovina: A cytogenetic study	5
Myricetin causes site-specific DNA damage via reactive oxygen species generation by redox interactions with copper ions	5
Evaluation of arsenic induced genotoxicity and its impact on life processes of Daphnia magna	5
Protective role of Cockayne Syndrome B (CSB) protein in maintaining genome integrity in human cells under oxidative stress	5
Mutagenicity of nitrosamines in enhanced Ames tests: A review of strain, metabolism, and solvent effects	4
Genotoxicity mode of action exploration of polyethylene glycol terephthalate (PET) acetic acid migration solution under repeated-dose exposure in rats	4
A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo	4
Photomutagenicity of N-nitrosoproline dissolved in non-aqueous solvent, oleic acid	4
Frequencies of micronuclei in buccal cells and their spatial distribution in a population living in proximity to coal mining areas in southern Brazil	4
Evaluation of genotoxic effects in workers and residents of rural areas exposed to pesticides in Brazil	4
Frequency of γ-H2AX foci, micronucleus formation, and radiation dose to the blood lymphocytes in pediatric and adult participants underwent computed tomography imaging	4
In vitro hepatic 3D cell models and their application in genetic toxicology: A systematic review	4
What are the effects of whole blood storage conditions on comet assay in terms of DNA damage and repair?	4
Liver-on-chip model and application in predictive genotoxicity and mutagenicity of drugs	4
The comet assay for the evaluation of gut content genotoxicity: Use in human studies as an early biomarker of colon cancer risk	4
The effect of aging on the repeated-dose liver micronucleus assay using N-nitrosodipropylamine, quinoline, and carbendazim	4
An investigation of DNA damage and DNA repair in chemical carcinogenesis triggered by small-molecule xenobiotics and in cancer: Thirty years with the comet assay	4
DNA damage in Brazilian newborns admitted to NICUs - association with maternal and neonatal outcomes	4
Quantifying telomere transcripts as tool to improve risk assessment for genetic instability and genotoxicity	4
Findings from international archived data: Fractionation reduces mortality risk of ionizing radiation for total doses below 4 Gray in rodents	3
Increased genotoxic damage in Sicilian donkeys reared in different conditions of air quality	3
Protective effects of nicotinamide mononucleotide on DNA damage and cell death in A549 cells and aging in C. elegans caused by hydrogen peroxide	3
Roles of base and nucleotide excision repair activities in cancer treatment: implications for prognosis and resistance to therapy in breast and colorectal cancers	3
Retraction notice to "Genotoxicity assessment of cerium oxide nanoparticles in female Wistar rats after acute oral exposure" Mutat. Res. Genet. Toxicol. Environ. Mutagen. 775–776C (2014) 7–19	3
Workers exposed to lead at a battery recycling plant in Mexico: Blood lead levels; DNA damage and repair in blood cells (comet assay)	3
Reduced genotoxicity of lignin-derivable replacements to bisphenol A studied using in silico, in vitro, and in vivo methods	3
The role of luteolin in modulation of acrylamide-induced genotoxicity and apoptosis in embryonic fibroblast cells	3
DNA damaging effects of occupational exposure to glass fibres. Response to Madl and Keeton paper	3
Editorial Board	3
Protective effect of quercetin and thymoquinone against genotoxicity and oxidative stress induced by ZnO nanoparticles in the Wistar rat model	3
Editorial Board	3
Aneugenic and clastogenic alterations in the DBA/IJ mouse model of rheumatoid arthritis treated with rituximab, an anti-CD20 antibody	3
Chemical characterization of Brazilian savannah Byrsonima species (muricis) and their impact on genomic instability and chemopreventive effects	3
Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats	3
The potential implications of dysregulated DNA damage repair genes and their modulators as adjuvants for current chemotherapy regimens in Retinoblastoma tumors	3
Evaluation of oxidative damage and genotoxicity in populations exposed to arsenic in drinking water from Santa Fe province, Argentina	3
Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations	3
Editorial Board	3
Retraction notice to “Levothyroxine synthesis impurities are neither mutagenic nor genotoxic: Insilico, Ames test and micronucleus test studies” [Mutat. Res. - Genet. Toxicol. Environ. Mutagenesis 898	3
A panel of visual bacterial biosensors for the rapid detection of genotoxic and oxidative damage: A proof of concept study	3
The effects of iodine 131 treatment on chromosomal and oxidative DNA damage in papillary thyroid carcinoma	3
The use of effect biomarkers in chemical mixtures risk assessment – Are they still important?	3
DNA damage and oxidative stress responses to pollution of Mytilus galloprovincialis L. from the Izmir Bay (Turkey): Seasonal evaluation	3
Oxide-nanoparticles induce in vitro DNA damage and genomic instability in human peripheral blood cells	3
Radiology personnel chronically exposed to low-dose ionizing radiation: Assessment of genotoxic damage with the buccal micronucleus cytome assay	3
Editorial Board	3
UVA causes specific mutagenic DNA damage through ROS production, rather than CPD formation, in Drosophila larvae	2
Bacterial effectors disrupt host DNA: Linking sputum microbiome profiles to chromosomal aberrations in leukocytes of lung cancer patients and healthy controls	2
Brazilian workers occupationally exposed to different toxic agents: A systematic review on DNA damage	2
Cellular uptake, induction of reactive oxygen species, and genotoxicity of differently sized cobalt oxide nanoparticles in human peripheral blood mononuclear cells in vitro	2
Safety evaluation of ethanolic extract from aerial flowering part of spiny globe thistle (Echinops spinosus) in mice: Phytochemical screening and genotoxicity	2
Methylated and ethylated dialkylphosphate metabolites of organophosphate pesticides: DNA damage in bone marrow cells of Balb/c mice	2
In vivo genotoxicity and water quality assessment reveal urban influences on the Capibaribe River, Northeastern Brazil	2
Genotoxicity of ultraviolet light and sunlight in the bacterium Caulobacter crescentus: Wavelength-dependence	2
Photogenotoxicity of N-nitrosoproline plus simultaneous UVA irradiation in human-derived keratinocytes	2
Links between telomere dysfunction and hallmarks of aging	2
Epigenetic effects of graphene oxide and its derivatives: A mini-review	2
Micronucleus assay of DNA damage among welders: Effects of welding processes	2
Micronucleus test in reptiles: Current and future perspectives	2
Frequencies of chromosomal aberrations and related biochemical parameters in welders	2
Editorial Board	2
Bruce Nathan Ames: A scientist to remember (December 16, 1928—October 5, 2024)	2
Applications of intelligent technology in the evaluation of mutagenicity	2
Evaluation of the in vivo acute toxicity and in vitro genotoxicity and mutagenicity of synthetic β-carboline alkaloids with selective cytotoxic activity against ovarian and breast cancer cell lines	2
LA-COMET group: In vivo application of the comet assay in animal and plant models, including wild species	2