OOIR: Observatory of International Research

Papers

(The H4-Index of Current Pharmaceutical Design is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Analysis of the Growth and Development of Children Born with ICSI of Epididymal and Testicular Spermatozoa: A Propensity Matching Study	113
Protective Effects of the Aqueous Extract of Malva sylvestris Plant against the Lethality and Histopathological Damage in Experimental Envenoming of Hemiscorpius lepturus Venom in Balb/c	97
Cytokines as Potential Therapeutic Targets and their Role in the Diagnosis and Prediction of Cancers	85
Drug Release and Stability Study of Innovated Losartan Potassium and Rosuvastatin Calcium Fixed-dose Combination Tablet	82
Mendelian Randomization Study on Serum Metabolites and Diabetic Nephropathy Risk: Identifying Potential Biomarkers for Early Intervention	72
Development of Chitosan-Coated Liposomes for Oral Delivery of Nadolol: Preparation, Characterization, and in vitro Permeability Studies	67
Non-synonymous Single Nucleotide Polymorphisms in Human ACE2 Gene May Affect the Infectivity of SARS-CoV-2 Omicron Subvariants	58
Computational Exploration of Flavonoids as HCV NS3/4A Protease Inhibitors: Advancing Antiviral Therapies to Mitigate Liver Cancer Risk	56
Prevalence and Death Rate of COVID-19 in Autoimmune Systemic Diseases in the First Three Pandemic Waves. Relationship with Disease Subgroups and Ongoing Therapies	55
Topoisomerase Enzyme Inhibitors as Potential Drugs Against Cancer: What Makes Them Selective or Dual? – A Review	54
Associations Between microRNA-related Genetic Polymorphisms and Clinical Response to Methotrexate in Chinese Rheumatoid Arthritis Patients	52
A Hydrogel for Nitric Oxide Sensitization Chemotherapy Mediated by Tumor Microenvironment Changes in 3D Spheroids and Breast Tumor Models	45
Salivary Antiviral and Antibacterial Properties in the Encounter of SARS-CoV-2	43
Traditional Uses, Phytochemistry, and Pharmacological Activities of Coleus amboinicus: A Comprehensive Review	41
Impact of Combination Therapy with Chemical Drugs and Megavoltage X-ray Exposure on Breast Cancer Stem Cells’ Viability and Proliferation of MCF-7 and MDA-MB-231 Cell Lines	37
Novel Approaches to the Management of Diabetes Mellitus in Patients with Coronary Artery Disease	36
Molecularly Imprinted Polymers (MIPs): A Multifaceted Tool in Modern Analysis	36
The Potential Mechanism of Liujunzi Decoction in the Treatment of Breast Cancer based on Network Pharmacology and Molecular Docking Technology	35
Nanoparticles in CNS Therapeutics: Pioneering Drug Delivery Advancements	35
Is Adrenaline Always the First Choice Therapy of Anaphylaxis? An Allergist-cardiologist Interdisciplinary Point of View	34
Rosuvastatin Improves Endothelial Dysfunction in Diabetes by Normalizing Endoplasmic Reticulum Stress via Calpain-1 Inhibition	32
Colorectal Cancer Stem Cell Biomarkers: Biological Traits and Prognostic Insights	30
The Progress of Immune Cells-induced Inflammatory Response in Gout	30
Immune-mediated Bowel Disease: Role of Intestinal Parasites and Gut Microbiome	28
Exploring 4D Printing Technology for Biomedical Applications	28

CRISPR-Cas9 for the Treatment of Transthyretin Cardiac Amyloidosis	28
Elucidation of the Molecular Mechanism of Compound Danshen Dripping Pills against Angina Pectoris based on Network Pharmacology and Molecular Docking	28
Tanshinone IIA Inhibits Epithelial-Mesenchymal Transition in Colitis-Associated Cancer in Mice by Regulating PTEN and ATPase Inhibitory Factor 1	27
Computational Approaches to Designing Antiviral Drugs against COVID-19: A Comprehensive Review	27
Role of Oxidative Stress and Inflammation in Insomnia Sleep Disorder and Cardiovascular Diseases: Herbal Antioxidants and Anti-inflammatory Coupled with Insomnia Detection using Machine Learning	27
Phytoestrogens: A Promising Therapeutic Approach for Endometriosis Management, Insights from Preclinical and Clinical Studies	27