OOIR: Observatory of International Research

Papers

(The H4-Index of Current Pharmaceutical Design is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Pathophysiology of Ischemic Stroke: Role of Oxidative Stress	237
Wnt/beta-catenin and PI3K/Akt/mTOR Signaling Pathways in Glioblastoma: Two Main Targets for Drug Design: A Review	76
Vaccinium myrtillus L. Fruits as a Novel Source of Phenolic Compounds with Health Benefits and Industrial Applications - A Review	59
Excitotoxicity as a Target Against Neurodegenerative Processes	52
Serum Uric Acid and Diabetes: From Pathophysiology to Cardiovascular Disease	47
Insect Cuticular Chitin Contributes to Form and Function	45
Artemia species: An Important Tool to Screen General Toxicity Samples	44
Vitamin D and Sleep Regulation: Is there a Role for Vitamin D?	42
Epidemiology of Non-alcoholic Fatty Liver Disease in North America	42
Current Nanoparticle Approaches in Nose to Brain Drug Delivery and Anticancer Therapy - A Review	42
Lipid-Based Nanosystem As Intelligent Carriers for Versatile Drug Delivery Applications	40
Polymer-Lipid Hybrid Nanoparticles: A Next-Generation Nanocarrier for Targeted Treatment of Solid Tumors	40
Dietary Amino Acids and Immunonutrition Supplementation in Cancer-Induced Skeletal Muscle Mass Depletion: A Mini-Review	40
Tribolium castaneum: A Model for Investigating the Mode of Action of Insecticides and Mechanisms of Resistance	40
Nanostructured Lipid Carriers as Potential Drug Delivery Systems for Skin Disorders	39
Oxidative Stress and Pathways of Molecular Hydrogen Effects in Medicine	36
Nanomedicines in Diagnosis and Treatment of Cancer: An Update	36
New Insights about Regulatory T Cells Distribution and Function with Exercise: The Role of Immunometabolism	35
Surface-Engineered Cancer Nanomedicine: Rational Design and Recent Progress	35
BPC 157 Rescued NSAID-cytotoxicity Via Stabilizing Intestinal Permeability and Enhancing Cytoprotection	34
The Role of Chloroquine and Hydroxychloroquine in Immune Regulation and Diseases	34
Drug Development for Central Nervous System Diseases Using In vitro Blood-brain Barrier Models and Drug Repositioning	34
Natural Agents Modulating ACE-2: A Review of Compounds with Potential against SARS-CoV-2 Infections	34
Solid Lipid Nanoparticles for Topical Drug Delivery: Mechanisms, Dosage Form Perspectives, and Translational Status	33
The Impact of Immune Cell-derived Exosomes on Immune Response Initiation and Immune System Function	33

Natural Compounds as Inhibitors of SARS-CoV-2 Main Protease (3CLpro): A Molecular Docking and Simulation Approach to Combat COVID-19	33
The Blood-Brain Barrier Interface in Diabetes Mellitus: Dysfunctions, Mechanisms and Approaches to Treatment	32
Dysmetabolic Iron Overload in Metabolic Syndrome	32
Curcumin for the Management of Periodontal Diseases: A Review	31
Enhancing Therapeutic Efficacy of Donepezil by Combined Therapy: A Comprehensive Review	31
Vesicular Transport Machinery in Brain Endothelial Cells: What We Know and What We Do not	31
Applications of Nanocarriers as Drug Delivery Vehicles for Active Phytoconstituents	31
Endothelial Dysfunction and Inflammation in Ischemic Stroke Pathogenesis	31