OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Chemical Biology is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Engineered metallobiocatalysts for energy–relevant reactions	191
Noncytotoxic catalytic enzyme functional mimics including cyanide poisoning antidotes	93
Glycoengineering in antigen-specific immunotherapies	78
Peptide-based molecules for the disruption of bacterial Hsp70 chaperones	77
Fluorogenic polymethine dyes by intramolecular cyclization	77
Recent advances in the structural analysis of adenylation domains in natural product biosynthesis	76
Proximity chemistries to study RNA biology at the subcellular scale	72
Imaging of proteases using activity-based probes	65
Glycosidase mechanisms: Sugar conformations and reactivity in endo- and exo-acting enzymes	63
Editorial Board	60
The Ramifications of synthetic biology	55
Characteristics of genetic tags for correlative light and electron microscopy	55
Recent advances in methods for quantifying the cell penetration of macromolecules	55
Covalent lysine targeting is coming of age	54
Chemical inhibitors of transcription-associated kinases	54
Recent advances in proximity labeling for chemical proteomics: Paving the way for in vivo applications	53
Toward universal binder discovery: Advances in display, computational design and in vivo platforms	49
Accessing and exploring the unusual chemistry by radical SAM-RiPP enzymes	47
Activity-based protein profiling in microbes and the gut microbiome	46
Always on the move: Mapping spatiotemporal interactome with proximity labeling in mammalian cells	46
Blurred lines: Crossing the boundaries between the chemical exposome and the metabolome	45
Self-resistance as a guide to discovering bioactive natural products	45
Caged lipid probes for controlling lipid levels on subcellular scales	45
Site-specific bioconjugation and nuclear imaging	45
Towards better red emitters for bioimaging: Innovations in rhodamine and cyanine chemistry	45

Controlling distance, time and reactivity: Chemical principles of proximity labeling	44
Synthetic transporters for oxoanions	43
Chemo- and opto-genetic tools for dissecting the role of membrane contact sites in living cells: Recent advances and limitations	43
From the forest floor to the lab: Insights into the diversity and complexity of mushroom polyketide synthases	42
Editorial Board	42
DVD-IgG1 antibody–drug conjugates: Expanding the landscape of targeted cancer therapy	41
Chemistry and biology of enzymes in protein glutathionylation	41
Genetically encoded fluorescent sensors for metals in biology	40
Advances in the understanding and exploitation of carbohydrate-active enzymes	40
Critical considerations in N-glycoproteomics	39
Genetic code expansion: Bridging synthetic biology precision and cellular complexity to decipher molecular mechanisms of diseases	39
Highlighting the roles of transition metals and speciation in chemical biology	39
Multinuclear non-heme iron dependent oxidative enzymes (MNIOs) involved in unusual peptide modifications	39
Selenium vitaminology: The connection between selenium, vitamin C, vitamin E, and ergothioneine	39