OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Chemical Biology is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Fluorogenic polymethine dyes by intramolecular cyclization	177
Small-molecule modulators of protein–RNA interactions	82
Glycosidase mechanisms: Sugar conformations and reactivity in endo- and exo-acting enzymes	81
Engineered metallobiocatalysts for energy–relevant reactions	71
Imaging of proteases using activity-based probes	71
Peptide-based molecules for the disruption of bacterial Hsp70 chaperones	68
Glycoengineering in antigen-specific immunotherapies	68
Recent advances in the structural analysis of adenylation domains in natural product biosynthesis	61
Noncytotoxic catalytic enzyme functional mimics including cyanide poisoning antidotes	60
Activity-based protein profiling in microbes and the gut microbiome	58
Editorial Board	57
Blurred lines: Crossing the boundaries between the chemical exposome and the metabolome	54
The Ramifications of synthetic biology	53
Characteristics of genetic tags for correlative light and electron microscopy	53
Recent advances in methods for quantifying the cell penetration of macromolecules	52
Chemical inhibitors of transcription-associated kinases	51
Site-specific bioconjugation and nuclear imaging	50
Synthetic transporters for oxoanions	50
Caged lipid probes for controlling lipid levels on subcellular scales	45
Covalent lysine targeting is coming of age	44
Always on the move: Mapping spatiotemporal interactome with proximity labeling in mammalian cells	44
Accessing and exploring the unusual chemistry by radical SAM-RiPP enzymes	44
Recent advances in proximity labeling for chemical proteomics: Paving the way for in vivo applications	43
Toward universal binder discovery: Advances in display, computational design and in vivo platforms	43
Chemistry and biology of enzymes in protein glutathionylation	43

Highlighting the roles of transition metals and speciation in chemical biology	42
Selenium vitaminology: The connection between selenium, vitamin C, vitamin E, and ergothioneine	42
DVD-IgG1 antibody–drug conjugates: Expanding the landscape of targeted cancer therapy	42
Critical considerations in N-glycoproteomics	40
Editorial Board	40
Advances in the understanding and exploitation of carbohydrate-active enzymes	40
Chemo- and opto-genetic tools for dissecting the role of membrane contact sites in living cells: Recent advances and limitations	39
From the forest floor to the lab: Insights into the diversity and complexity of mushroom polyketide synthases	39
Multinuclear non-heme iron dependent oxidative enzymes (MNIOs) involved in unusual peptide modifications	38
Editorial Board	37
Editorial Board	37
Genetically encoded fluorescent sensors for metals in biology	37