OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Chemical Biology is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Corrigendum to “Shedding light on complexity of protein–protein interactions in cancer” [Curr Opin Chem Biol 53 (2019) 75-81]	198
Fluorogenic polymethine dyes by intramolecular cyclization	129
Glycoengineering in antigen-specific immunotherapies	123
Noncytotoxic catalytic enzyme functional mimics including cyanide poisoning antidotes	91
Imaging of proteases using activity-based probes	86
Small-molecule modulators of protein–RNA interactions	70
Engineered metallobiocatalysts for energy–relevant reactions	69
Peptide-based molecules for the disruption of bacterial Hsp70 chaperones	64
Glycosidase mechanisms: Sugar conformations and reactivity in endo- and exo-acting enzymes	60
Recent advances in the structural analysis of adenylation domains in natural product biosynthesis	60
Recent advances in methods for quantifying the cell penetration of macromolecules	57
Extendable and explainable deep learning for pan-cancer radiogenomics research	56
Recent advances in proximity labeling for chemical proteomics: Paving the way for in vivo applications	56
Synthetic transporters for oxoanions	51
The Ramifications of synthetic biology	48
Blurred lines: Crossing the boundaries between the chemical exposome and the metabolome	48
Activity-based protein profiling in microbes and the gut microbiome	46
Characteristics of genetic tags for correlative light and electron microscopy	45
New strategies for fluorescently labeling proteins in the study of amyloids	45
Caged lipid probes for controlling lipid levels on subcellular scales	44
Accessing and exploring the unusual chemistry by radical SAM-RiPP enzymes	43
Site-specific bioconjugation and nuclear imaging	42
Chemical inhibitors of transcription-associated kinases	42
Chemical engineering of bacterial effectors for regulating cell signaling and responses	42
From the forest floor to the lab: Insights into the diversity and complexity of mushroom polyketide synthases	41

Genetically encoded fluorescent sensors for metals in biology	40
Network biology bridges the gaps between quantitative genetics and multi-omics to map complex diseases	40
Chemistry and biology of enzymes in protein glutathionylation	39
Chemical probes for tagging mycobacterial lipids	39
Chemo- and opto-genetic tools for dissecting the role of membrane contact sites in living cells: Recent advances and limitations	39
Multinuclear non-heme iron dependent oxidative enzymes (MNIOs) involved in unusual peptide modifications	38
Advances in the understanding and exploitation of carbohydrate-active enzymes	38
Critical considerations in N-glycoproteomics	38
Past, present, and perspectives of protein N-terminal methylation	36
Highlighting the roles of transition metals and speciation in chemical biology	36
Selenium vitaminology: The connection between selenium, vitamin C, vitamin E, and ergothioneine	36
Opportunity knocks for uncovering the new function of an understudied nucleosome remodeling complex member, the bromodomain PHD finger transcription factor, BPTF	36