OOIR: Observatory of International Research

Papers

(The median citation count of Critical Care is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19	716
Acute respiratory failure in COVID-19: is it “typical” ARDS?	464
COVID-19 pneumonia: ARDS or not?	451
Host susceptibility to severe COVID-19 and establishment of a host risk score: findings of 487 cases outside Wuhan	376
The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection	369
The unique characteristics of COVID-19 coagulopathy	344
COVID-19: ICU delirium management during SARS-CoV-2 pandemic	337
Psychological stress of ICU nurses in the time of COVID-19	292
Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019— results from a systematic review and meta-analysis	274
Incidence of ARDS and outcomes in hospitalized patients with COVID-19: a global literature survey	273
Biomarkers of sepsis: time for a reappraisal	270
Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China	250
Delirium and encephalopathy in severe COVID-19: a cohort analysis of ICU patients	234
Corticosteroid use in COVID-19 patients: a systematic review and meta-analysis on clinical outcomes	230
Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients	223
Can artificial intelligence help for scientific writing?	218
Predictive values of neutrophil-to-lymphocyte ratio on disease severity and mortality in COVID-19 patients: a systematic review and meta-analysis	217
Clinical determinants for fatality of 44,672 patients with COVID-19	200
Ventilator-associated pneumonia in critically ill patients with COVID-19	195
Treatment of COVID-19: old tricks for new challenges	191
Prediction of the development of acute kidney injury following cardiac surgery by machine learning	186
Special attention to nurses’ protection during the COVID-19 epidemic	183
Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis	176
Emerging SARS-CoV-2 variants of concern and potential intervention approaches	176
Mortality rates of patients with COVID-19 in the intensive care unit: a systematic review of the emerging literature	175

Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19	170
Exosomal miR-30d-5p of neutrophils induces M1 macrophage polarization and primes macrophage pyroptosis in sepsis-related acute lung injury	161
Clinical ethics recommendations for the allocation of intensive care treatments in exceptional, resource-limited circumstances: the Italian perspective during the COVID-19 epidemic	155
Effect of timing of intubation on clinical outcomes of critically ill patients with COVID-19: a systematic review and meta-analysis of non-randomized cohort studies	155
Revisited: Therapeutic and toxic blood concentrations of more than 1100 drugs and other xenobiotics	153
Thrombotic and hemorrhagic events in critically ill COVID-19 patients: a French monocenter retrospective study	149
Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients	149
The gut microbiome’s role in the development, maintenance, and outcomes of sepsis	148
Acute kidney injury in SARS-CoV-2 infected patients	147
Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, China	146
A new clinical trial to test high-dose vitamin C in patients with COVID-19	145
Acute complications and mortality in hospitalized patients with coronavirus disease 2019: a systematic review and meta-analysis	139
The association of low serum albumin level with severe COVID-19: a systematic review and meta-analysis	131
Prevalence and impact of acute renal impairment on COVID-19: a systematic review and meta-analysis	130
Patients with COVID-19 in 19 ICUs in Wuhan, China: a cross-sectional study	128
High-flow nasal oxygen in patients with COVID-19-associated acute respiratory failure	127
SARS-CoV-2 viral load in sputum correlates with risk of COVID-19 progression	127
Artificial Intelligence in the Intensive Care Unit	126
Neurological manifestations of COVID-19: a systematic review	123
Soluble urokinase plasminogen activator receptor (suPAR) as an early predictor of severe respiratory failure in patients with COVID-19 pneumonia	123
Respiratory physiology of COVID-19-induced respiratory failure compared to ARDS of other etiologies	119
Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review	119
ARDS Subphenotypes: Understanding a Heterogeneous Syndrome	119
COVID-19 and ECMO: the interplay between coagulation and inflammation—a narrative review	115
Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain	115
Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method	115
Long-term outcomes after critical illness: recent insights	114
Herpes simplex virus and cytomegalovirus reactivations among severe COVID-19 patients	114
A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19	114
Longitudinal changes of inflammatory parameters and their correlation with disease severity and outcomes in patients with COVID-19 from Wuhan, China	111
Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring	108
Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy: a multicenter, adjusted cohort study	108
High-density lipoproteins during sepsis: from bench to bedside	104
Elevation of plasma angiotensin II level is a potential pathogenesis for the critically ill COVID-19 patients	104
Nafamostat mesylate treatment in combination with favipiravir for patients critically ill with Covid-19: a case series	104
Nutrition of the COVID-19 patient in the intensive care unit (ICU): a practical guidance	102
Dangers of hyperoxia	102
Incidence of acute kidney injury in COVID-19 infection: a systematic review and meta-analysis	100
Age and sex differences in soluble ACE2 may give insights for COVID-19	99
Thrombotic and haemorrhagic complications in critically ill patients with COVID-19: a multicentre observational study	99
Lung ultrasound findings in patients with COVID-19 pneumonia	95
Ethics guidelines on COVID-19 triage—an emerging international consensus	94
The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition	94
The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study	94
Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intens	93
Personalized mechanical ventilation in acute respiratory distress syndrome	92
Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study	91
Risks of ventilator-associated pneumonia and invasive pulmonary aspergillosis in patients with viral acute respiratory distress syndrome related or not to Coronavirus 19 disease	91
Preparing for COVID-19: early experience from an intensive care unit in Singapore	90
Familial cluster of COVID-19 infection from an asymptomatic	90

Markers of endothelial and epithelial pulmonary injury in mechanically ventilated COVID-19 ICU patients	90
Comparison between first and second wave among critically ill COVID-19 patients admitted to a French ICU: no prognostic improvement during the second wave?	89
Risk factors for candidemia: a prospective matched case-control study	89
Early awake prone position combined with high-flow nasal oxygen therapy in severe COVID-19: a case series	86
A physiological approach to understand the role of respiratory effort in the progression of lung injury in SARS-CoV-2 infection	85
Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus	85
Vitamin C levels in patients with SARS-CoV-2-associated acute respiratory distress syndrome	85
Update of the treatment of nosocomial pneumonia in the ICU	84
Adjuvant corticosteroid therapy for critically ill patients with COVID-19	83
Preparing your intensive care unit for the COVID-19 pandemic: practical considerations and strategies	83
Atorvastatin associated with decreased hazard for death in COVID-19 patients admitted to an ICU: a retrospective cohort study	83
Prolonged prone position ventilation for SARS-CoV-2 patients is feasible and effective	83
Clinical characteristics of invasive pulmonary aspergillosis in patients with COVID-19 in Zhejiang, China: a retrospective case series	80
Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial	80
Prognosis when using extracorporeal membrane oxygenation (ECMO) for critically ill COVID-19 patients in China: a retrospective case series	80
Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19	79
The role of telemedicine during the COVID-19 epidemic in China—experience from Shandong province	79
Neutrophil-to-lymphocyte ratio as a predictive biomarker for moderate-severe ARDS in severe COVID-19 patients	78
Acute skeletal muscle wasting and dysfunction predict physical disability at hospital discharge in patients with critical illness	78
Platelet-derived exosomes promote neutrophil extracellular trap formation during septic shock	78
Gut-liver crosstalk in sepsis-induced liver injury	78
Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients: a multicenter retrospective study in 188 patients in an un-inundated French region	78
Brain–heart interaction after acute ischemic stroke	77
Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review	77
Nebulised heparin as a treatment for COVID-19: scientific rationale and a call for randomised evidence	76
VEGF-D: a novel biomarker for detection of COVID-19 progression	76
Molecular mechanisms of sex bias differences in COVID-19 mortality	76
COVID-19 and the RAAS—a potential role for angiotensin II?	75
Body temperature correlates with mortality in COVID-19 patients	74
Right ventricular-arterial uncoupling independently predicts survival in COVID-19 ARDS	74
Prehospital pulse oximetry: a red flag for early detection of silent hypoxemia in COVID-19 patients	73
Comparison of published guidelines for management of coagulopathy and thrombosis in critically ill patients with COVID 19: implications for clinical practice and future investigations	72
Prognostic value of bedside lung ultrasound score in patients with COVID-19	72
Thromboembolic complications in critically ill COVID-19 patients are associated with impaired fibrinolysis	72
How to measure blood pressure using an arterial catheter: a systematic 5-step approach	71
Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes	71
Systemic hypoferremia and severity of hypoxemic respiratory failure in COVID-19	71
Safe patient transport for COVID-19	70
Effect of mechanical power on intensive care mortality in ARDS patients	70
Blocking IL-1 to prevent respiratory failure in COVID-19	69
Multimodal non-invasive assessment of intracranial hypertension: an observational study	69
Burnout and Joy in the Profession of Critical Care Medicine	69
Infliximab against severe COVID-19-induced cytokine storm syndrome with organ failure—a cautionary case series	67
COVID-19: a hypothesis regarding the ventilation-perfusion mismatch	67
The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study	66
Failure of target attainment of beta-lactam antibiotics in critically ill patients and associated risk factors: a two-center prospective study (EXPAT)	66
Relationship between ventilator-associated pneumonia and mortality in COVID-19 patients: a planned ancillary analysis of the coVAPid cohort	66
A Clinician’s Guide to Management of Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Critically Ill Patients	66
Right ventricular failure in septic shock: characterization, incidence and impact on fluid responsiveness	65
Bedside calculation of mechanical power during volume- and pressure-controlled mechanical ventilation	65
CXCL10 could drive longer duration of mechanical ventilation during COVID-19 ARDS	65
Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore	63
COVID-19 mortality and ICU admission: the Italian experience	62
Monitoring Patient Respiratory Effort During Mechanical Ventilation: Lung and Diaphragm-Protective Ventilation	62
Co-infections in COVID-19 critically ill and antibiotic management: a prospective cohort analysis	61
Dosing of thromboprophylaxis and mortality in critically ill COVID-19 patients	61
Effect of tranexamic acid on thrombotic events and seizures in bleeding patients: a systematic review and meta-analysis	60
Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia	60
Machine learning model for early prediction of acute kidney injury (AKI) in pediatric critical care	59
The use of venous Doppler to predict adverse kidney events in a general ICU cohort	59
Plasma levels of soluble ACE2are associated with sex, Metabolic Syndrome, and its biomarkers in a large cohort, pointing to a possible mechanism for increased severity in COVID-19	58
Machine-learning-based COVID-19 mortality prediction model and identification of patients at low and high risk of dying	58
Incidence and mortality of pulmonary embolism in COVID-19: a systematic review and meta-analysis	58
Antifungal prophylaxis for prevention of COVID-19-associated pulmonary aspergillosis in critically ill patients: an observational study	58
Administration of umbilical cord mesenchymal stem cells in patients with severe COVID-19 pneumonia	57
Timing of norepinephrine initiation in patients with septic shock: a systematic review and meta-analysis	57
Treatment of COVID-19-associated ARDS with mesenchymal stromal cells: a multicenter randomized double-blind trial	57
High flow nasal therapy versus noninvasive ventilation as initial ventilatory strategy in COPD exacerbation: a multicenter non-inferiority randomized trial	57
Heating, ventilation and air conditioning (HVAC) in intensive care unit	56
Insight into ECMO, mortality and ARDS: a nationwide analysis of 45,647 ECMO runs	56
Admission decisions to intensive care units in the context of the major COVID-19 outbreak: local guidance from the COVID-19 Paris-region area	56
Early corticosteroids are associated with lower mortality in critically ill patients with COVID-19: a cohort study	56
Initial antimicrobial management of sepsis	55
The effect of higher versus lower protein delivery in critically ill patients: a systematic review and meta-analysis of randomized controlled trials	55
Extracorporeal cardiopulmonary resuscitation in adult patients with out-of-hospital cardiac arrest: a retrospective large cohort multicenter study in Japan	55
Deploying unsupervised clustering analysis to derive clinical phenotypes and risk factors associated with mortality risk in 2022 critically ill patients with COVID-19 in Spain	54
Helmet CPAP to treat hypoxic pneumonia outside the ICU: an observational study during the COVID-19 outbreak	54
Association between furosemide administration and outcomes in critically ill patients with acute kidney injury	54
ECMO use in COVID-19: lessons from past respiratory virus outbreaks—a narrative review	54
Noninvasive respiratory support outside the intensive care unit for acute respiratory failure related to coronavirus-19 disease: a systematic review and meta-analysis	54

Computed tomography assessment of PEEP-induced alveolar recruitment in patients with severe COVID-19 pneumonia	53
Timing of antibiotic therapy in the ICU	53
Systematic early versus late mobilization or standard early mobilization in mechanically ventilated adult ICU patients: systematic review and meta-analysis	52
Prevalence of post-intensive care syndrome among Japanese intensive care unit patients: a prospective, multicenter, observational J-PICS study	52
Multicenter evaluation of a syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia	52
Sepsis is associated with mitochondrial DNA damage and a reduced mitochondrial mass in the kidney of patients with sepsis-AKI	52
Auxora versus standard of care for the treatment of severe or critical COVID-19 pneumonia: results from a randomized controlled trial	51
Two subphenotypes of septic acute kidney injury are associated with different 90-day mortality and renal recovery	51
Elevated central venous pressure is associated with increased mortality and acute kidney injury in critically ill patients: a meta-analysis	51
Immune effects of PI3K/Akt/HIF-1α-regulated glycolysis in polymorphonuclear neutrophils during sepsis	50
International variation in the management of severe COVID-19 patients	50
Evolving outcomes of extracorporeal membrane oxygenation support for severe COVID-19 ARDS in Sorbonne hospitals, Paris	50
The challenge of ventilator-associated pneumonia diagnosis in COVID-19 patients	50
Resuscitation fluid types in sepsis, surgical, and trauma patients: a systematic review and sequential network meta-analyses	50
Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times?	50
Association between perioperative fluid administration and postoperative outcomes: a 20-year systematic review and a meta-analysis of randomized goal-directed trials in major visceral/noncardiac surge	49
Managing COVID-19 in resource-limited settings: critical care considerations	49
Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study	49
Blood purification therapy with a hemodiafilter featuring enhanced adsorptive properties for cytokine removal in patients presenting COVID-19: a pilot study	49
High-flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease patients after extubation: a multicenter, randomized controlled trial	49
Cardiac injury associated with severe disease or ICU admission and death in hospitalized patients with COVID-19: a meta-analysis and systematic review	48
Brain tight junction protein expression in sepsis in an autopsy series	48
Monocyte distribution width (MDW) performance as an early sepsis indicator in the emergency department: comparison with CRP and procalcitonin in a multicenter international European prospective study	48
Hemoperfusion: technical aspects and state of the art	47
Cerebral venous sinus thrombosis associated with thrombocytopenia post-vaccination for COVID-19	47
Antibiotic therapeutic drug monitoring in intensive care patients treated with different modalities of extracorporeal membrane oxygenation (ECMO) and renal replacement therapy: a prospective, observat	47
Advanced respiratory monitoring in COVID-19 patients: use less PEEP!	47
Inhaled nitric oxide in patients admitted to intensive care unit with COVID-19 pneumonia	47
Large language models and the perils of their hallucinations	47
Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients	47
The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial	47
Blood purification with a cytokine adsorber for the elimination of myoglobin in critically ill patients with severe rhabdomyolysis	47
Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic	47
Invasive pulmonary aspergillosis among intubated patients with SARS-CoV-2 or influenza pneumonia: a European multicenter comparative cohort study	47
Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation	46
The rate and assessment of muscle wasting during critical illness: a systematic review and meta-analysis	46
A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice	46
Prone positioning under VV-ECMO in SARS-CoV-2-induced acute respiratory distress syndrome	45
ECMO during the COVID-19 pandemic: when is it unjustified?	45
The impact of right ventricular injury on the mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis	45
Severe Covid-19 disease: rather AVDS than ARDS?	45
Physiology of the Respiratory Drive in ICU Patients: Implications for Diagnosis and Treatment	44
Therapeutic plasma exchange in patients with COVID-19 pneumonia in intensive care unit: a retrospective study	44
Causes and characteristics of death in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: a retrospective cohort study	44
Inhaled nitric oxide for critically ill Covid-19 patients: a prospective study	44
Bedside POCUS during ward emergencies is associated with improved diagnosis and outcome: an observational, prospective, controlled study	44
Mortality in septic patients treated with vitamin C: a systematic meta-analysis	44
Invasive mechanical ventilation in COVID-19 patient management: the experience with 469 patients in Wuhan	44
Efficacy of tocilizumab in patients with COVID-19 ARDS undergoing noninvasive ventilation	44
PEEP levels in COVID-19 pneumonia	43
Plasma exchange in critically ill COVID-19 patients	43
Recommendations for the use of vascular access in the COVID-19 patients: an Italian perspective	43
Acute kidney injury in ECMO patients	43
Should we deny ICU admission to the elderly? Ethical considerations in times of COVID-19	42
Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated intensive care patients—a randomized clinical trial	41
The therapeutic efficacy of adjunct therapeutic plasma exchange for septic shock with multiple organ failure: a single-center experience	41
Energy delivery guided by indirect calorimetry in critically ill patients: a systematic review and meta-analysis	41
Transcranial Doppler as a screening test to exclude intracranial hypertension in brain-injured patients: the IMPRESSIT-2 prospective multicenter international study	41
Recommendations for core critical care ultrasound competencies as a part of specialist training in multidisciplinary intensive care: a framework proposed by the European Society of Intensive Care Medi	41
Restricted visitation policies in acute care settings during the COVID-19 pandemic: a scoping review	41
Argatroban versus heparin in patients without heparin-induced thrombocytopenia during venovenous extracorporeal membrane oxygenation: a propensity-score matched study	41
Staphylococcus aureus ventilator-associated pneumonia in patients with COVID-19: clinical features and potential inference with lung dysbiosis	40
Venoarterial extracorporeal membrane oxygenation as mechanical circulatory support in adult septic shock: a systematic review and meta-analysis with individual participant data meta-regression analysi	40
Intravenous vitamin C administration to patients with septic shock: a pilot randomised controlled trial	40
Identification and characterization of neutrophil heterogeneity in sepsis	40
Factors for success of awake prone positioning in patients with COVID-19-induced acute hypoxemic respiratory failure: analysis of a randomized controlled trial	40
Drug dosing in the critically ill obese patient—a focus on sedation, analgesia, and delirium	40
Ventilator-associated pneumonia in the era of COVID-19 pandemic: How common and what is the impact?	40
Prone positioning combined with high-flow nasal cannula in severe noninfectious ARDS	40
COVID-19 infection epidemic: the medical management strategies in Heilongjiang Province, China	40
VENTILatOry strategies in patients with severe traumatic brain injury: the VENTILO Survey of the European Society of Intensive Care Medicine (ESICM)	40
Expert clinical pharmacological advice may make an antimicrobial TDM program for emerging candidates more clinically useful in tailoring therapy of critically ill patients	40
Prone positioning in severe ARDS requiring extracorporeal membrane oxygenation	40
Vasopressor Choice and Timing in Vasodilatory Shock	40
Adverse events associated with administration of vasopressor medications through a peripheral intravenous catheter: a systematic review and meta-analysis	39
Early effects of ventilatory rescue therapies on systemic and cerebral oxygenation in mechanically ventilated COVID-19 patients with acute respiratory distress syndrome: a prospective observational st	39
Sex differences in survival after out-of-hospital cardiac arrest: a meta-analysis	39
How COVID-19 pandemic changed our communication with families: losing nonverbal cues	39
Unmatched ventilation and perfusion measured by electrical impedance tomography predicts the outcome of ARDS	38
Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis	38
Coagulation phenotypes in sepsis and effects of recombinant human thrombomodulin: an analysis of three multicentre observational studies	38
A systematic review of biomarkers multivariately associated with acute respiratory distress syndrome development and mortality	38
Changes in shunt, ventilation/perfusion mismatch, and lung aeration with PEEP in patients with ARDS: a prospective single-arm interventional study	38
Identification of novel sublingual parameters to analyze and diagnose microvascular dysfunction in sepsis: the NOSTRADAMUS study	38
Neuromuscular blocking agents (NMBA) for COVID-19 acute respiratory distress syndrome: a multicenter observational study	38
Neutrophil Elastase Inhibitors: A potential prophylactic treatment option for SARS-CoV-2-induced respiratory complications?	38
“War to the knife” against thromboinflammation to protect endothelial function of COVID-19 patients	38
HSV-1 reactivation is associated with an increased risk of mortality and pneumonia in critically ill COVID-19 patients	37
Corticosteroids as risk factor for COVID-19-associated pulmonary aspergillosis in intensive care patients	37
Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients	37
The fluid challenge	37
Significance of body temperature in elderly patients with sepsis	37
Severe pulmonary embolism in COVID-19 patients: a call for increased awareness	37
Recommendations for hemodynamic monitoring for critically ill children—expert consensus statement issued by the cardiovascular dynamics section of the European Society of Paediatric and Neonatal Inten	37
Time-to-antibiotics and clinical outcomes in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study	37