Apoptosis

Papers
(The TQCC of Apoptosis is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Release mechanisms of major DAMPs206
The function and mechanism of ferroptosis in cancer112
Mechanism of interaction between autophagy and apoptosis in cancer95
BCL-2 family deregulation in colorectal cancer: potential for BH3 mimetics in therapy70
BCL-2 protein family: attractive targets for cancer therapy58
Terpenoids’ anti-cancer effects: focus on autophagy53
BAX-dependent mitochondrial pathway mediates the crosstalk between ferroptosis and apoptosis51
Targeting of cancer cell death mechanisms by resveratrol: a review51
Mechanisms of cancer cell death induction by paclitaxel: an updated review46
The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases41
Programmed cell death detection methods: a systematic review and a categorical comparison41
Baicalein attenuates caspase-independent cells death via inhibiting PARP-1 activation and AIF nuclear translocation in cerebral ischemia/reperfusion rats39
Ca2+ overload- and ROS-associated mitochondrial dysfunction contributes to δ-tocotrienol-mediated paraptosis in melanoma cells39
Programmed cell death, redox imbalance, and cancer therapeutics32
Potential role of TrkB agonist in neuronal survival by promoting CREB/BDNF and PI3K/Akt signaling in vitro and in vivo model of 3-nitropropionic acid (3-NP)-induced neuronal death31
COVID-19 disrupts spermatogenesis through the oxidative stress pathway following induction of apoptosis30
Photodynamic therapy: apoptosis, paraptosis and beyond29
Glucocorticoid-induced autophagy and apoptosis in bone29
Progesterone induces apoptosis by activation of caspase-8 and calcitriol via activation of caspase-9 pathways in ovarian and endometrial cancer cells in vitro29
FTO inhibits UPRmt-induced apoptosis by activating JAK2/STAT3 pathway and reducing m6A level in adipocytes27
Apoptosis in Alzheimer’s disease: insight into the signaling pathways and therapeutic avenues27
New insights into targeting mitochondria in ischemic injury25
Acetylcholinesterase promotes apoptosis in insect neurons24
Circumventing the Crabtree effect: forcing oxidative phosphorylation (OXPHOS) via galactose medium increases sensitivity of HepG2 cells to the purine derivative kinetin riboside24
Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax23
XIAP as a multifaceted molecule in Cellular Signaling21
Apoptosis induced by SARS-CoV-2: can we target it?21
A potent protective effect of baicalein on liver injury by regulating mitochondria-related apoptosis20
Pyroptosis in acute pancreatitis and its therapeutic regulation20
Nobiletin as an inducer of programmed cell death in cancer: a review20
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation19
Gedunin isolated from the mangrove plant Xylocarpus granatum exerts its anti-proliferative activity in ovarian cancer cells through G2/M-phase arrest and oxidative stress-mediated intrinsic apoptosis19
The extracellular lactate-to-pyruvate ratio modulates the sensitivity to oxidative stress-induced apoptosis via the cytosolic NADH/NAD+ redox state18
Intracellular leucine-rich alpha-2-glycoprotein-1 competes with Apaf-1 for binding cytochrome c in protecting MCF-7 breast cancer cells from apoptosis18
Cytokine regulation of apoptosis-induced apoptosis and apoptosis-induced cell proliferation in vascular smooth muscle cells18
Soluble receptor for advanced glycation end-products promotes angiogenesis through activation of STAT3 in myocardial ischemia/reperfusion injury17
Citarinostat and Momelotinib co-target HDAC6 and JAK2/STAT3 in lymphoid malignant cell lines: a potential new therapeutic combination17
DNA damage induces STING mediated IL-6-STAT3 survival pathway in triple-negative breast cancer cells and decreased survival of breast cancer patients17
Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects17
miR-21 protects neonatal rats from hypoxic-ischemic brain damage by targeting CCL317
The regulation of necroptosis and perspectives for the development of new drugs preventing ischemic/reperfusion of cardiac injury17
Cytosolic DNA sensing through cGAS and STING is inactivated by gene mutations in pangolins16
The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis16
Maslinic acid differentially exploits the MAPK pathway in estrogen-positive and triple-negative breast cancer to induce mitochondrion-mediated, caspase-independent apoptosis16
Interconnections among major forms of regulated cell death16
Regulatory T cells are less sensitive to glucocorticoid hormone induced apoptosis than CD4+ T cells16
Ischemia reperfusion injury induces pyroptosis and mediates injury in steatotic liver thorough Caspase 1 activation16
COVID-19 causes neuronal degeneration and reduces neurogenesis in human hippocampus16
Regulation of autophagy of the heart in ischemia and reperfusion16
miR-30b-5p inhibits cancer progression and enhances cisplatin sensitivity in lung cancer through targeting LRP816
Casein kinase 1α mediates eryptosis: a review14
Inverse regulation of GSDMD and GSDME gene expression during LPS-induced pyroptosis in RAW264.7 macrophage cells14
p53 m6A modulation sensitizes hepatocellular carcinoma to apatinib through apoptosis14
Heat shock proteins-driven stress granule dynamics: yet another avenue for cell survival14
The pro-apoptotic ARTS protein induces neutrophil apoptosis, efferocytosis, and macrophage reprogramming to promote resolution of inflammation14
Triclosan induces apoptosis in Burkitt lymphoma-derived BJAB cells through caspase and JNK/MAPK pathways13
The interplay between apoptosis and ferroptosis mediated by ER stress13
Synergistic inhibitory effect of berberine and icotinib on non-small cell lung cancer cells via inducing autophagic cell death and apoptosis13
m6A writer WTAP targets NRF2 to accelerate bladder cancer malignancy via m6A-dependent ferroptosis regulation12
Hemocompatible LAT1-inhibitor can induce apoptosis in cancer cells without affecting brain amino acid homeostasis12
Cuproptosis identifies respiratory subtype of renal cancer that confers favorable prognosis12
Regulation of autophagy as a therapeutic option in glioblastoma12
Cardiac Mitochondrial PTEN-L determines cell fate between apoptosis and survival during chronic alcohol consumption12
Role of apoptosis repressor with caspase recruitment domain (ARC) in cell death and cardiovascular disease12
LINC00511 promotes cervical cancer progression by regulating the miR-497-5p/MAPK1 axis12
Upregulation of microRNA-532 enhances cardiomyocyte apoptosis in the diabetic heart12
LncRNA FGD5-AS1 promotes the malignant phenotypes of ovarian cancer cells via targeting miR-142-5p11
Doxorubicin sensitizes cancer cells to Smac mimetic via synergistic activation of the CYLD/RIPK1/FADD/caspase-8-dependent apoptosis11
Pyroptosis, a target for cancer treatment?11
Ambra1 regulates apoptosis and chemosensitivity in breast cancer cells through the Akt-FoxO1-Bim pathway11
Tumor cell-derived exosome RNF126 affects the immune microenvironment and promotes nasopharyngeal carcinoma progression by regulating PTEN ubiquitination11
N6-methyladenosine writer METTL3 accelerates the sepsis-induced myocardial injury by regulating m6A-dependent ferroptosis11
The role of lncRNA OIP5-AS1 in cancer development and progression11
Epoxyazadiradione exhibit activities in head and neck squamous cell carcinoma by targeting multiple pathways11
Valproic acid upregulates the expression of the p75NTR/sortilin receptor complex to induce neuronal apoptosis10
The delay in cell death caused by the induction of autophagy by P2Et extract is essential for the generation of immunogenic signals in melanoma cells10
Orientin downregulating oxidative stress-mediated endoplasmic reticulum stress and mitochondrial dysfunction through AMPK/SIRT1 pathway in rat nucleus pulposus cells in vitro and attenuated interverte10
The role of the DFF40/CAD endonuclease in genomic stability10
Inhibition of miR-130b-3p restores autophagy and attenuates intervertebral disc degeneration through mediating ATG14 and PRKAA110
Understanding the mechanistic roles of environmental heavy metal stressors in regulating ferroptosis: adding new paradigms to the links with diseases9
RAB25 confers resistance to chemotherapy by altering mitochondrial apoptosis signaling in ovarian cancer cells9
Benzofuran pyran hybrid prevents glucocorticoid induced osteoporosis in mice via modulation of canonical Wnt/β-catenin signaling9
Piperlongumine, a piper alkaloid, enhances the efficacy of doxorubicin in breast cancer: involvement of glucose import, ROS, NF-κB and lncRNAs9
H2S probe CPC inhibits autophagy and promotes apoptosis by inhibiting glutathionylation of Keap1 at Cys4349
Sphingosylphosphorylcholine alleviates hypoxia-caused apoptosis in cardiac myofibroblasts via CaM/p38/STAT3 pathway9
Human umbilical cord mesenchymal stem cell-derived exosomes carrying miR-1827 downregulate SUCNR1 to inhibit macrophage M2 polarization and prevent colorectal liver metastasis9
The analog of cGAMP, c-di-AMP, activates STING mediated cell death pathway in estrogen-receptor negative breast cancer cells9
High glucose-induced ROS-accumulation in embryo-larval stages of zebrafish leads to mitochondria-mediated apoptosis9
Molecular mechanisms of cell death in bronchopulmonary dysplasia9
Phosphodiesterase 5 inhibitor sildenafil potentiates the antitumor activity of cisplatin by ROS-mediated apoptosis: a role of deregulated glucose metabolism9
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