Apoptosis

Article	Citations
Succinate-mediated SUCNR1 activation in tumor-associated macrophages promotes M2 polarization and cetuximab resistance in colorectal cancer: in vitro and in vivo insights	413
Disruption of iron homeostasis by HERC2-FTL axis leads to chondrocyte loss and exacerbates osteoarthritis	347
Spatially defined danger zone shapes gastric cancer progression through CCDC80+ fibroblast–induced CD8+ T cell dysfunction	272
N6-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m6A/PD-L1 manner	156
Breast cancer: taxonomy, distribution analysis, risk factors, predictive biomarkers, and modern treatment method	115
An integrated investigation of sulfotransferases (SULTs) in hepatocellular carcinoma and identification of the role of SULT2A1 on stemness	101
Transcription factor EB-mediated autophagy affects cell migration and inhibits apoptosis to promote endometriosis	78
Exosomes derived from FN14-overexpressing BMSCs activate the NF-κB signaling pathway to induce PANoptosis in osteosarcoma	63
Global trends in PANoptosis research: bibliometrics and knowledge graph analysis	61
Programmed cell death lives	61
Molecular probes for monitoring pyroptosis: design, imaging and theranostic application	61
Removing therapy-induced senescent cancer cells targets and potentiates the response of pancreatic cancer cells toward PARP inhibitors as maintenance therapy	59
ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP	56
Monitoring yeast regulated cell death: trespassing the point of no return to loss of plasma membrane integrity	53
Mitophagy: a novel avenue for herbal medicines alleviating myocardial ischemia/reperfusion injury	52
The circTIMP2/miR-106a/TIMP2 tumor-suppressive axis versus tumor-derived exosomal counteraction in gastric cancer	51
Higher replication potential of West Nile virus governs apoptosis induction in human neuroblastoma cells	51
Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak	51
Caspase-1 in cancer and inflammatory diseases: a potential therapeutic target	50
Multiple myeloma with high expression of SLC7A11 is sensitive to erastin-induced ferroptosis	50
The STING signaling pathways and bacterial infection	50
Tumor cell-derived exosome RNF126 affects the immune microenvironment and promotes nasopharyngeal carcinoma progression by regulating PTEN ubiquitination	49
The CXCL8-CXCR2 axis promotes M2 macrophage polarization in ovarian cancer via RASGRP4-mediated mTOR-STAT3 signaling	48
The ATG14: multi-layer autophagy control and an emerging therapeutic target in cancer	47
Augmenter of liver regeneration reduces mitochondria-derived ROS and NLRP3 inflammasome activation through PINK1/Parkin-mediated mitophagy in ischemia-reperfusion-induced renal tubular injury	47

LncRNA PVT1 delays skin photoaging by sequestering miR-551b-3p to release AQP3 expression via ceRNA mechanism	47
Research progress on the mechanism of FOXO protein in sepsis	46
Targeting cuproptosis in liver cancer: Molecular mechanisms and therapeutic implications	45
Machine learning-based analysis of programmed cell death types and key genes in intervertebral disc degeneration	45
PTGR1-mediated immune evasion mechanisms in late-stage triple-negative breast cancer: mechanisms of M2 macrophage infiltration and CD8+ T cell suppression	45
Transcriptomic responses of cumulus granulosa cells to SARS-CoV-2 infection during controlled ovarian stimulation	44
A double-edged sword: role of apoptosis repressor with caspase recruitment domain (ARC) in tumorigenesis and ischaemia/reperfusion (I/R) injury	43
LncRNA PVT1 drives macrophage polarization and triple-negative breast cancer progression via PPARγ-mediated transcriptional activation​	42
GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria	41
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release	41
Regulation of autophagy of the heart in ischemia and reperfusion	40
m6A methyltransferase WTAP regulates myocardial ischemia reperfusion injury through YTHDF1/FOXO3a signaling	40
Dual role of endoplasmic reticulum stress-ATF-6 activation in autophagy and apoptosis induced by cyclic stretch in myoblast	39
An immunogenic cell death-related signature predicts prognosis and immunotherapy response in stomach adenocarcinoma	38
PLAGL2-STAU1-NCOA4 axis enhances gastric cancer peritoneal metastasis by resisting ferroptosis via ferritinophagy	35
Manipulating the PANoptosome: baseless hype or a newfound hope for human immunity?	35
Necroptosis in myocardial ischaemia-reperfusion injury: current update on mechanisms, therapeutic targets, and translational potential	34
Genipin protects against acute liver injury by abrogating ferroptosis via modification of GPX4 and ALOX15-launched lipid peroxidation in mice	33
Autophagy regulation of pyroptosis and ferroptosis: a new strategy for colorectal cancer treatment	32
Endothelial SPRY1 deficiency associates with angiogenic-metabolic reprogramming in pulmonary arterial hypertension: a multi-omics analysis of bulk and single-cell transcriptomic profiles	31
Endothelial HMGB1-AIM2 axis worsens myocardial ischemia—reperfusion injury by regulating endothelial pyroptosis	31
Rising impact of cell death research	31
Correction: Targeting PNPO to suppress tumor growth via inhibiting autophagic flux and to reverse paclitaxel resistance in ovarian cancer	30
Neural stem cell-derived exosomal PA2G4 induces ANXA2 degradation to promote mitophagy and alleviate neuronal oxidative stress in cerebral ischemia/reperfusion	30
Exploring the role of ITGB6: fibrosis, cancer, and other diseases	30
Novel dual inhibitor targeting CDC25 and HDAC for treating triple-negative breast cancer	30
Activation of the 20S proteasome core particle prevents cell death induced by oxygen- and glucose deprivation in cultured cortical neurons	30
Analysis of cuproptosis-related lncRNA signature for predicting prognosis and tumor immune microenvironment in pancreatic cancer	29
CD95 ligand drives abdominal aortic aneurysm progression through Caspase-8-mediated GSDMD-dependent endothelial pyroptosis: modulation by SRC kinase	29
Aquaporin-1 stabilizes β-catenin to promote NLRP3 inflammasome-mediated pyroptosis in rheumatoid arthritis	29
Bufalin targeting BFAR inhibits the occurrence and metastasis of gastric cancer through PI3K/AKT/mTOR signal pathway	28
The role of the NcRNA/ferroptosis axis in lung cancer: molecular mechanisms and potential therapeutic targets	28
LINC00511 promotes cervical cancer progression by regulating the miR-497-5p/MAPK1 axis	28
A ZFP42/MARK2 regulatory network reduces the damage of retinal ganglion cells in glaucoma: a study based on GEO dataset and in vitro experiments	28
5-Aminolevulinic acid-mediated photodynamic therapy in combination with kinase inhibitor lapatinib enhances glioblastoma cell death	28
Exosome-mediated triple drug delivery enhances apoptosis in pancreatic cancer cells	27
LncRNA ENSMUST_147219 mediates the progression of ischemic acute kidney injury by targeting the miR-221-5p/IRF6 axis	27
Zincoptosis: does it exist?	26
Exploring a specialized programmed-cell death patterns to predict the prognosis and sensitivity of immunotherapy in cutaneous melanoma via machine learning	26
Harnessing cuproptosis: a new avenue for targeted cancer therapies	26
Integrative analysis of genes reveals endoplasmic reticulum stress-related immune responses involved in dilated cardiomyopathy with fibrosis	26
HMGB1: a multifaceted mediator of cell death pathways in cardiovascular diseases	26
Casein kinase 1α mediates eryptosis: a review	26
Ferroptosis-centered strategies: redefining therapeutic resistance & adaptation in modern oncology	26
CACNA1C-AS2 inhibits cell proliferation and suppresses cell migration and invasion via targeting FBXO45 and PI3K/AKT/mTOR pathways in glioma	25
The emerging role of cholesterol metabolism in gynecologic cancer development and therapy	25
CHI3L1 promotes myocardial fibrosis via regulating lncRNA TUG1/miR-495-3p/ETS1 axis	24
Metrnl in health and disease: tissue-specific actions and signaling networks	24
XIAP as a multifaceted molecule in Cellular Signaling	24
DDIT3 drives nucleus pulposus cell PANoptosis and intervertebral disc degeneration progression	24

Overview of genetic and epigenetic regulation of human papillomavirus and apoptosis in cervical cancer	23
The critical role of X-linked inhibitor of apoptosis protein (XIAP) in tumor development	23
Ferroptosis: a novel therapeutic warrior in the battle against leukemia	23
The role of TIGIT-CD226-PVR axis in mediating T cell exhaustion and apoptosis in NSCLC	23
Critical roles of tubular mitochondrial ATP synthase dysfunction in maleic acid-induced acute kidney injury	22
His-tagged pro-apoptotic peptides: enhancing cell internalization and anticancer effect in vitro	22
Human umbilical cord mesenchymal stem cell-derived exosomes carrying miR-1827 downregulate SUCNR1 to inhibit macrophage M2 polarization and prevent colorectal liver metastasis	21
Suppression of endothelial cell PANoptosis: qingyi decoction targets the TMAO-HMGB1 pathway to mitigate lung injury in acute pancreatitis rats	21
Oxidative stress and ferroptosis in diabetic cardiomyopathy: mechanistic interplay and therapeutic implications	21
Macrophage ferroptosis in hematologic malignancies: emerging mechanisms and therapeutic implications	21
Brazilin alleviates acute lung injury via inhibition of ferroptosis through the SIRT3/GPX4 pathway	21
Live-cell imaging and mathematical analysis of the “community effect” in apoptosis	21
PANoptosis: a potential new target for programmed cell death in breast cancer treatment and prognosis	20
Targeting mitochondrial apoptosis in septic lung injury: protective potential of omega-3 fatty acids	20
USP43 impairs cisplatin sensitivity in epithelial ovarian cancer through HDAC2-dependent regulation of Wnt/β-catenin signaling pathway	20
Pyroptosis as a double-edged sword in colorectal cancer: Molecular mechanisms and therapeutic opportunities	20
Correction to: NF-κB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis	20
The N6-methyladenosine writer METTL3 promotes breast cancer progression through YTHDF2-dependent posttranscriptional silencing of GSDMD	20
Cuproptosis identifies respiratory subtype of renal cancer that confers favorable prognosis	19
Stemness-related lncRNAs signature as a biologic prognostic model for head and neck squamous cell carcinoma	19
Anticancer effect and apoptosis induction by azaflavanone derivative in human prostate cancer cells	19
MARCH5 promotes aerobic glycolysis to facilitate ovarian cancer progression via ubiquitinating MPC1	19
Combined effects of natural products and exercise on apoptosis pathways in obesity-related skeletal muscle dysfunction	19
Targeted delivery of RGD-JEG-3-EVs for placental vascular regeneration in preeclampsia: from molecular mechanism toward therapy	19
The regulation of necroptosis by ubiquitylation	19
Deciphering macrophage heterogeneity and factors driving M2 polarization in lung adenocarcinoma through single-cell RNA sequencing	19
EFNA4-enhanced deubiquitination of SLC7A11 inhibits ferroptosis in hepatocellular carcinoma	19
The GATA3-RFPL3-ASK1 axis suppresses breast cancer growth and lung metastasis	19
Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission	19
Unveiling the hidden role of disulfidptosis in kidney renal clear cell carcinoma: a prognostic signature for personalized treatment	18
Integrating single-cell sequencing and machine learning to uncover the role of mitophagy in subtyping and prognosis of esophageal cancer	18
Is long-term administration of PLD-pegylated liposomal doxorubicin able to induce oral cancer?	18
IGF2BP3 boosts lactate generation to accelerate gastric cancer immune evasion	18
Role of the USP family in autophagy regulation and cancer progression	18
Emerging role of PANoptosis in kidney diseases: molecular mechanisms and therapeutic opportunities	18
Unlocking Parkinson’s disease: the role of microRNAs in regulation, diagnosis, and therapy	18
Ferroptosis crosstalk in anti-tumor immunotherapy: molecular mechanisms, tumor microenvironment, application prospects	17
Bushen Jianpi Tiaoxue Decoction (BJTD) inhibits the LIF-mTOR signaling axis to regulate mitochondrial function and alleviate cyclophosphamide-induced diminished ovarian reserve	17
DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells	17
SFG enhances apoptosis of hepatocellular carcinoma by inhibiting tunneling nanotubes-mediated mitochondrial transport in the tumor microenvironment	17
Role of ferroptosis in food-borne mycotoxin-induced toxicities	17
TBC1D10B promotes tumor progression in colon cancer via PAK4‑mediated promotion of the PI3K/AKT/mTOR pathway	17
SNCA is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients	17
Adenylate kinase 4 promotes radioresistance by suppressing radiation-induced ferroptosis through metabolic regulation in glioblastoma	17
Correction to: Integrative analysis of genes reveals endoplasmic reticulum stress-related immune responses involved in dilated cardiomyopathy with fibrosis	17
Circ_0000523 regulates miR-1184/COL1A1/PI3K/Akt pathway to promote nasopharyngeal carcinoma progression	17
Enhancing the efficacy of VEGF inhibitors by co-inhibition of HIF in the treatment of glioblastoma	17
Phillyrin promotes flap survival by mitigating pyroptosis through the TLR4/NF-κB/NLRP3 signaling pathway	16
Crosstalk between protein lipidation and ubiquitination in tumor biology	16
The mechanistic study of quercetin in the treatment of alcoholic brain injury via the JNK/P38 MAPK signaling pathway	16
DDI2 promotes tumor metastasis and resists antineoplastic drugs-induced apoptosis in colorectal cancer	16
Ferroptosis dysregulation, mitochondrial dysfunction, and iron metabolism alterations are correlated with aggressiveness in uveal melanoma	16
DLD is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients	16
Prognostic implications and therapeutic opportunities related to CAF subtypes in CMS4 colorectal cancer: insights from single-cell and bulk transcriptomics	16
GJB2 as a novel prognostic biomarker associated with immune infiltration and cuproptosis in ovarian cancer	15
Pollutant-regulated mitophagy: new perspectives in environmental toxicology	15
Targeting ferroptosis: a novel insight against myocardial infarction and ischemia–reperfusion injuries	15
microRNA-205 represses breast cancer metastasis by perturbing the rab coupling protein [RCP]-mediated integrin β1 recycling on the membrane	15
Beyond the hype: the glycolysis–pyroptosis axis in intervertebral disc degeneration and the path to therapeutic translation	15
METTL3 safeguard cancer cells from programmed cell death during detachment from their surrounding extracellular matrix	15
A novel programmed cell death signature predicts clinical outcomes in clear cell renal cell carcinoma and identifies PLK1 as a therapeutic target	15
A new perspective on iron-dependent cell death: PRDX-1-mediated ferroptosis in tumor cells	15
Ochratoxin A-induced mitochondrial pathway apoptosis and ferroptosis by promoting glycolysis	15
Reparative effects of VCAM-1 high-performance MSC-derived exosomes on aged diabetic cardiomyocyte injury: a focus on ferroptosis suppression	15
Development and experimental validation of a machine learning-based disulfidptosis-related ferroptosis score for hepatocellular carcinoma	15
A deadly taste: linking bitter taste receptors and apoptosis	15
Correction: Atorvastatin inhibits the apoptosis of human umbilical vein endothelial cells induced by angiotensin II via the lysosomalmitochondrial axis	14
Microplastics promote chemoresistance by mediating lipid metabolism and suppressing pyroptosis in colorectal cancer	14
EVA1A reverses lenvatinib resistance in hepatocellular carcinoma through regulating PI3K/AKT/p53 signaling axis	14
Research progress on the mechanism of curcumin in cerebral ischemia/reperfusion injury: a narrative review	14
Multi-omics nominates VDAC2 as a candidate protective locus in sepsis-associated cholesterol dysregulation	14
Bibliometric analysis and mini-review of global research on pyroptosis in the field of cancer	14
Understanding the mechanistic roles of environmental heavy metal stressors in regulating ferroptosis: adding new paradigms to the links with diseases	14
Emerging role of RNA m6A modifications in laryngeal squamous cell carcinoma: insights into tumorigenesis and therapeutic potential	13
Intravenous immunoglobulin ameliorates doxorubicin-induced intestinal mucositis by inhibiting the Syk/PI3K/Akt axis and ferroptosis	13
Targeting BACH1 by HPPE inhibits the Wnt/β-catenin pathway and malignant phenotype in glioblastoma cells	13
Novel impact of metal ion-induced cell death on diabetic cardiomyopathy pathogenesis and therapy	13
Bufalin inhibits immune escape in metastatic colorectal cancer by regulating M2 macrophage polarization	13
Role of circAGFG1 as an oncogene in triple-negative breast cancer	13
The gut microbial metabolite phenylacetylglutamine increases susceptibility to atrial fibrillation after myocardial infarction through ferroptosis and NLRP3 inflammasome	13

NUFIP1-engineered exosomes modulate propofol-induced neurotoxicity in neonatal rats via the ERS apoptotic pathway	13
MLKL and other necroptosis-related genes promote the tumor immune cell infiltration, guiding for the administration of immunotherapy in bladder urothelial carcinoma	13
Diallyl disulfide in oncotherapy: molecular mechanisms and therapeutic potentials	13
IGF2BP2 promotes lncRNA DANCR stability mediated glycolysis and affects the progression of FLT3-ITD + acute myeloid leukemia	13
Inhibition of ferroptosis by icariin treatment attenuates excessive ethanol consumption-induced atrial remodeling and susceptibility to atrial fibrillation, role of SIRT1	13
Necroptosis inhibitors: mechanisms of action and therapeutic potential	12
Mild hypothermia alleviates oxygen−glucose deprivation/reperfusion-induced apoptosis by inhibiting ROS generation, improving mitochondrial dysfunction and regulating DNA damage repair pathway in PC12	12
Retraction Note: Apicidin induces endoplasmic reticulum stress- and mitochondrial dysfunction-associated apoptosis via phospholipase Cγ1- and Ca2+-dependent pathway in mouse Neuro-2a neuroblastoma cel	12
Polymeric immunoglobulin receptor (pIgR) in cancer progression: a critical role and potential therapeutic target	12
SLITRK6 promotes the progression of lung adenocarcinoma by regulating PI3K/AKT/mTOR signaling and Warburg effect	12
A novel 8-hydroxyquinoline derivative induces breast cancer cell death through paraptosis and apoptosis	12
BACH2 ameliorates cell apoptosis and autophagy as a molecular switch of BCL-2/Beclin-1 complex in myocardial infarction	12
Photobiomodulation therapy moderates cancer cachexia-associated muscle wasting through activating PI3K/AKT/FoxO3a pathway	12
Role of POLE2/GINS1-mediated AKT/mTOR pathway in RCC autophagy, proliferation, and metastasis: evidences from bioinformatic, clinical, and experimental data	12
AIM2-PANoptosome-driven PANoptosis in hepatic lipid dysregulation induced by β-HCH and nanoplastics co-exposure	12
Targeted delivery of FAK siRNA by engineered exosomes to reverse cetuximab resistance via activating paraptosis in colon cancer	12
Integrated explainable machine learning and multi-omics analysis for survival prediction in cancer with immunotherapy response	12
CXCR4 enhances the inhibitory effects of bone mesenchymal stem cells on lung cell apoptosis in a rat model of smoking-induced COPD	12
Pharmacological inhibition of STING-mediated GPX4 autophagic degradation by 4-octyl itaconate ameliorates sepsis-induced acute kidney injury	12
Enhancing or inhibiting apoptosis? The effects of ucMSC-Ex in the treatment of different degrees of traumatic pancreatitis	11
Cell death-associated genes as novel diagnostic biomarkers for autism spectrum disorder	11
Cross-regulation of autophagy and pyroptosis: a new perspective on the inflammatory microenvironment of atherosclerosis	11
Role of APR3 in cancer: apoptosis, autophagy, oxidative stress, and cancer therapy	11
Tumor-suppressive E3 ubiquitin ligase CHIP inhibits the PBK/ERK axis to repress stem cell properties and radioresistance in non-small cell lung cancer	11
PARP-2 mediates cardiomyocyte aging and damage induced by doxorubicin through SIRT1 Inhibition	11
Machine learning framework develops neutrophil extracellular traps model for clinical outcome and immunotherapy response in lung adenocarcinoma	11
Understanding the molecular mechanism of regeneration through apoptosis-induced compensatory proliferation studies - updates and future aspects	11
Triptolide induces PANoptosis in macrophages and causes organ injury in mice	11
Programmed cell death in lung cancer: mechanisms, immune responses, and therapeutics	11
TM2, a novel semi-synthetic taxoid, exerts anti-MDR activity in NSCLC by inhibiting P-gp function and stabilizing microtubule polymerization	10
Mechanisms of cuproptosis and its relevance to distinct diseases	10
PRELP inhibits colorectal cancer progression by suppressing epithelial-mesenchymal transition and angiogenesis via the inactivation of the FGF1/PI3K/AKT pathway	10
Retraction Note: ICB3E induces iNOS expression by ROS-dependent JNK and ERK activation for apoptosis of leukemic cells	10
BH3-mimetics or DNA-damaging agents in combination with RG7388 overcome p53 mutation-induced resistance to MDM2 inhibition	10
PANoptosis: potential new targets and therapeutic prospects in digestive diseases	10
Ferroptosis: underlying mechanisms and involvement in neurodegenerative diseases	10
DNMT2/TRDMT1 gene knockout compromises doxorubicin-induced unfolded protein response and sensitizes cancer cells to ER stress-induced apoptosis	10
Disulfidptosis-related long non-coding RNA signature predicts the prognosis, tumor microenvironment, immunotherapy, and antitumor drug options in colon adenocarcinoma	10
Escaping cell death via TRAIL decoy receptors: a systematic review of their roles and expressions in colorectal cancer	10
N6-methyladenosine reader protein IGF2BP1 suppresses CD8 + T cells-mediated tumor cytotoxicity and apoptosis in colon cancer	10
MRG15 promotes cell apoptosis through inhibition of mitophagy in hyperlipidemic acute pancreatitis	10
Advancing the frontiers of colorectal cancer treatment: harnessing ferroptosis regulation	10
Investigation of GPR143 as a promising novel marker for the progression of skin cutaneous melanoma through bioinformatic analyses and cell experiments	10
IRF-1-inhibited lncRNA XIST regulated the osteogenic differentiation via miR-450b/FBXW7 axis	10
Neutrophil extracellular traps mediate TLR9/Merlin axis to resist ferroptosis and promote triple negative breast cancer progression	10
Mechanistic study on the role of multi-pathway autophagy in ovarian aging: literature review	10
Identifying SLC2A6 as the novel protective factor in breast cancer by TP53-related genes affecting M1 macrophage infiltration	10
Benefits of high-intensity interval training compared to continuous training to reduce apoptotic markers in female rats with cisplatin nephrotoxicity – possible modulatory role of IL-11	10
Notch1 signaling activation alleviates coronary microvascular dysfunction through histone modification of Nrg-1 via the interaction between NICD and GCN5	10
Ambra1 in cancer: implications for clinical oncology	10
Looking at the fraction with Annexin V⁺ and propidium iodide⁺: insights into cell death types from preclinical studies in solid and haematological cancers	9
COL8A1-positive cancer-associated fibroblasts are drivers of 5-fluorouracil resistance in colorectal cancer	9
The role and mechanisms of vitamin A in suppressing hepatic stellate cell activation	9
TNF-α and RPLP0 drive the apoptosis of endothelial cells and increase susceptibility to high-altitude pulmonary edema	9
A bibliometric and knowledge-map analysis of anoikis from 2003 to 2022	9
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer	9
Exploiting autophagy and related pathways: pioneering new horizons in cataract therapy	9
Targeting PANoptosis in atherosclerosis: bridging cell death mechanisms and therapy	9
Detection of apoptotic cells based on in situ hybridization chain reaction using specific hairpins	9
Microglia programmed cell death in neurodegenerative diseases and CNS injury	9
Zhongfeng Capsules protects against cerebral ischemia–reperfusion injury via mediating the phosphoinositide 3-kinase/Akt and toll-like receptor 4/nuclear factor kappa B signaling pathways by regulatin	9
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia	9
Role of PANoptosis in cancer: Molecular mechanisms and therapeutic opportunities	9
CD24 flags anastasis in melanoma cells	9
Cell death and immune escape in the tumor microenvironment: associated mechanisms, opportunities and challenges	9
Acetylation of FOXO1 activates Bim expression involved in CVB3 induced cardiomyocyte apoptosis	9
Advances in the research of gasdermin-dependent pyroptosis mechanisms and therapeutic targets in inflammatory diseases	9
Cuproptosis in lung cancer: therapeutic options and prognostic models	9
Development and validation of ferroptosis-related lncRNA signature and immune-related gene signature for predicting the prognosis of cutaneous melanoma patients	9
Potential role of human umbilical cord stem cells-derived exosomes as novel molecular inhibitors of hepatocellular carcinoma growth	9
YTHDF1-mediated m6A modification promotes cisplatin resistance in ovarian cancer via the FZD7/Wnt/β-catenin pathway	9
The cGAS-STING pathway in fibroblast microenvironment: from molecular mechanisms to targeted therapies	9
Glucocorticoid-induced activation of NOX/ROS/NF-κB signaling in MSCs contributes to the development of GONFH	8
Synergistic cytotoxicity of decitabine and YM155 in leukemia cells through upregulation of SLC35F2 and suppression of MCL1 and survivin expression	8
mTOR pathway mediates endoplasmic reticulum stress-induced CD4+ T cell apoptosis in septic mice	8
m6A modification and its clinical applications in gynaecological cancer	8
Acute high-altitude hypoxia induced NLRP3 inflammasome activation in pulmonary artery smooth muscle cells by BMAL1 targeting mitochondrial VDAC1-mediated MtDNA leakage	8
Targeting lipid metabolism for ferroptotic cancer therapy	8
High glucose-induced ROS-accumulation in embryo-larval stages of zebrafish leads to mitochondria-mediated apoptosis	8
Decoding the concealed transcriptional signature of the apoptosis-related BCL2 antagonist/killer 1 (BAK1) gene in human malignancies	8
The CHI3L1 protein plays role as a protecting factor against autophagy in glioblastoma cells	8
ITGAM-macrophage modulation as a potential strategy for treating neutrophilic Asthma: insights from bioinformatics analysis and in vivo experiments	8
Copper modulates cell fate through the PLK1–FOXO3a–β-catenin signaling pathway by differentially regulating cuproptosis and EMT	8
Improved antitumor immunity of chemotherapy in OSCC treatment by Gasdermin-E mediated pyroptosis	8
The Mutual Regulatory Role of Ferroptosis and Immunotherapy in Anti-tumor Therapy	8
Loss of AR-regulated AFF3 contributes to prostate cancer progression and reduces ferroptosis sensitivity by downregulating ACSL4 based on single-cell sequencing analysis	8
Vitamin D3 alleviates lung fibrosis of type 2 diabetic rats via SIRT3 mediated suppression of pyroptosis	8
Deubiquitinating enzyme USP28 inhibitor AZ1 alone and in combination with cisplatin for the treatment of non-small cell lung cancer	8
PANoptosis: a potential target of atherosclerotic cardiovascular disease	8
Retraction Note: Progesterone induces apoptosis by activation of caspase-8 and calcitriol via activation of caspase-9 pathways in ovarian and endometrial cancer cells in vitro	8
NAC and DNase I synergistically reduce NETs to attenuate severe acute pancreatitis via suppressing the NETs/NF-κB/CXCL3 pathway	8
Unveiling the multifaceted roles of BCL3: biological functions and disease implications	8
SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis	8
Decoding microglial metabolic cell death and PANoptosis hub genes in subacute phase of traumatic brain injury: a multi-omics and experimental validation study	8
Ferroptosis and cuproptposis in kidney Diseases: dysfunction of cell metabolism	8