OOIR: Observatory of International Research

Papers

(The H4-Index of Apoptosis is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Spatially defined danger zone shapes gastric cancer progression through CCDC80+ fibroblast–induced CD8+ T cell dysfunction	418
Global trends in PANoptosis research: bibliometrics and knowledge graph analysis	356
Disruption of iron homeostasis by HERC2-FTL axis leads to chondrocyte loss and exacerbates osteoarthritis	282
Monitoring yeast regulated cell death: trespassing the point of no return to loss of plasma membrane integrity	160
Removing therapy-induced senescent cancer cells targets and potentiates the response of pancreatic cancer cells toward PARP inhibitors as maintenance therapy	117
Exosomes derived from FN14-overexpressing BMSCs activate the NF-κB signaling pathway to induce PANoptosis in osteosarcoma	104
Breast cancer: taxonomy, distribution analysis, risk factors, predictive biomarkers, and modern treatment method	84
Transcription factor EB-mediated autophagy affects cell migration and inhibits apoptosis to promote endometriosis	65
N6-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m6A/PD-L1 manner	61
Molecular probes for monitoring pyroptosis: design, imaging and theranostic application	61
Succinate-mediated SUCNR1 activation in tumor-associated macrophages promotes M2 polarization and cetuximab resistance in colorectal cancer: in vitro and in vivo insights	61
ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP	61
Programmed cell death lives	57
An integrated investigation of sulfotransferases (SULTs) in hepatocellular carcinoma and identification of the role of SULT2A1 on stemness	55
Mitophagy: a novel avenue for herbal medicines alleviating myocardial ischemia/reperfusion injury	53
Ablation of FBXO38 triggers lysosome-dependent STING degradation to drive chemotherapy resistance in cervical cancer	53
Higher replication potential of West Nile virus governs apoptosis induction in human neuroblastoma cells	53
The STING signaling pathways and bacterial infection	52
Caspase-1 in cancer and inflammatory diseases: a potential therapeutic target	52
The CXCL8-CXCR2 axis promotes M2 macrophage polarization in ovarian cancer via RASGRP4-mediated mTOR-STAT3 signaling	52
The ATG14: multi-layer autophagy control and an emerging therapeutic target in cancer	51
Augmenter of liver regeneration reduces mitochondria-derived ROS and NLRP3 inflammasome activation through PINK1/Parkin-mediated mitophagy in ischemia-reperfusion-induced renal tubular injury	50
Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak	50
Machine learning-based analysis of programmed cell death types and key genes in intervertebral disc degeneration	49
Multiple myeloma with high expression of SLC7A11 is sensitive to erastin-induced ferroptosis	48

Research progress on the mechanism of FOXO protein in sepsis	47
The circTIMP2/miR-106a/TIMP2 tumor-suppressive axis versus tumor-derived exosomal counteraction in gastric cancer	47
LncRNA PVT1 delays skin photoaging by sequestering miR-551b-3p to release AQP3 expression via ceRNA mechanism	46
Genipin protects against acute liver injury by abrogating ferroptosis via modification of GPX4 and ALOX15-launched lipid peroxidation in mice	46
Tumor cell-derived exosome RNF126 affects the immune microenvironment and promotes nasopharyngeal carcinoma progression by regulating PTEN ubiquitination	46
Transcriptomic responses of cumulus granulosa cells to SARS-CoV-2 infection during controlled ovarian stimulation	45
LncRNA PVT1 drives macrophage polarization and triple-negative breast cancer progression via PPARγ-mediated transcriptional activation	45
GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria	44
Targeting cuproptosis in liver cancer: Molecular mechanisms and therapeutic implications	41
Necroptosis in myocardial ischaemia-reperfusion injury: current update on mechanisms, therapeutic targets, and translational potential	41
PLAGL2-STAU1-NCOA4 axis enhances gastric cancer peritoneal metastasis by resisting ferroptosis via ferritinophagy	40
PTGR1-mediated immune evasion mechanisms in late-stage triple-negative breast cancer: mechanisms of M2 macrophage infiltration and CD8+ T cell suppression	40
An immunogenic cell death-related signature predicts prognosis and immunotherapy response in stomach adenocarcinoma	40
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release	39