OOIR: Observatory of International Research

Papers

(The TQCC of Cytokine & Growth Factor Reviews is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Editorial Board	287
Corrigendum to “Ferroptosis in immune cells: Implications for tumor immunity and cancer therapy” [Cytokine Growth Factor Rev. 84 (2025) 59–73]	157
Unveiling cytokine charge disparity as a potential mechanism for immune regulation	151
Navigating IL-6: From molecular mechanisms to therapeutic breakthroughs	140
COVID-19: From emerging variants to vaccination	138
Targeting the metabolism and immune system in pancreatic ductal adenocarcinoma: Insights and future directions	128
Editorial Board	125
Editorial Board	103
Editorial Board	93
Erratum to “TLR-Based therapeutic strategies for Hepatocellular carcinoma” [Cytokine Growth Factor Rev. Volume 85 2025 Pages 179–189]	91
Proteomics analysis of circulating small extracellular vesicles: Focus on the contribution of EVs to tumor metabolism	88
Metabolic Regulation of cGAS-STING Signaling in the Tumor Microenvironment: Dual Immune Roles and Therapeutic Implications	87
Insights into IL-6/JAK/STAT3 signaling in the tumor microenvironment: Implications for cancer therapy	85
CDK4/6 inhibition in hormone receptor-positive/HER2-negative breast cancer: Biological and clinical aspects	80
Targeting cytokines: Reshaping the pancreatic tumor microenvironment	77
Progranulinopathy: A diverse realm of disorders linked to progranulin imbalances	77
Editorial Board	68
Molecular mechanisms of regulation of IL-1 and its receptors	68
Immuno-metabolic control of the balance between Th17-polarized and regulatory T-cells during HIV infection	62
Natural killers or natural regulators? Dual roles of NK cells in checkpoint immunotherapy	59
Epithelial-to-mesenchymal transition transcription factors: New strategies for mesenchymal tissue regeneration	59
Cytokine symphony: Deciphering the tumor microenvironment and metastatic axis in oral cancer	54
The immunodynamics of pulmonary fibrosis	54
Novel insights into neuroinflammatory mechanisms in traumatic brain injury: Focus on pattern recognition receptors as therapeutic targets	54
Central role of Galectin-3 at the cross-roads of cardiac inflammation and fibrosis: Implications for heart failure and transplantation	53

Exogenous drug-induced mouse models of atopic dermatitis	53
TGF-β mediated drug resistance in solid cancer	52
Immunosuppressive tumor microenvironment and uterine fibroids: Role in collagen synthesis	50
Chemokines and chemokine receptors: Insights from human disease and experimental models of helminthiasis	50
Scarless wound healing: Current insights from the perspectives of TGF-β, KGF-1, and KGF-2	47
The cGAS-STING pathway: Post-translational modifications and functional implications in diseases	47
Role of FOXO3 in regulation of redox homeostasis and promotion of red blood cell longevity in sickle cell disease	47
Tumor microenvironment, histone modifications, and myeloid-derived suppressor cells	47
Exosomes as a modulator of immune resistance in human cancers	46
Exosomes: Another intercellular lipometabolic communication mediators in digestive system neoplasms?	46
Decoding the roles of heat shock proteins in liver cancer	45
Multifaceted role of CD14 in innate immunity and tissue homeostasis	45
Editorial Board	44
Post COVID-19 pandemic Inflammatory Insights into Cancer: Consequences for immunotherapy	43
Modulation of IL-33/ST2 signaling as a potential new therapeutic target for cardiovascular diseases	42
The roles of cell-cell and organ-organ crosstalk in the type 2 diabetes mellitus associated inflammatory microenvironment	42
The role of neurotransmitter signaling in colorectal cancer progression: Opportunities for drug repurposing	42
Exploring inflammatory and fibrotic mechanisms driving diabetic nephropathy progression	41
Quantitative and qualitative differences in the activation of a fibroblast growth factor receptor by different FGF ligands	41
Targeting the NLRP3 inflammasome in sepsis: Molecular mechanisms and therapeutic strategies	40
Forgetting COVID-19 – Introduction to the special issue	40
The impact of adipokines on vascular networks in adipose tissue	39
From senescence to scarring: Exploring TGF-β signaling in cellular aging, fibrotic remodeling, and pulmonary fibrosis	39
Nuclear translocation of RON receptor tyrosine kinase. New mechanistic and functional insights	39
Extracellular vesicles: Emerging mediators of cell communication in gastrointestinal cancers exhibiting metabolic abnormalities	37
Exosomal noncoding RNA-mediated spatiotemporal regulation of lipid metabolism: Implications in immune evasion and chronic inflammation	35
The role of Extracellular Vesicles in glycolytic and lipid metabolic reprogramming of cancer cells: Consequences for drug resistance	34
Fibroblast growth factor homologous factors in neural signaling: Molecular mechanisms and disease-relevant dysregulation	34
Liquid biopsy analysis of lipometabolic exosomes in pancreatic cancer	34
Role of exosomes in transferring chemoresistance through modulation of cancer glycolytic cell metabolism	33
mTOR in programmed cell death and its therapeutic implications	33
Therapeutic inhibition of the JAK-STAT pathway in the treatment of inflammatory bowel disease	32
Cholecystokinin and gastrin as immune modulating hormones: Implications and applications	32
Ferroptosis in immune cells: Implications for tumor immunity and cancer therapy	32
Glioblastoma-associated macrophages: A key target in overcoming glioblastoma therapeutic resistance	32
Interleukin-17: A pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders	32
Exosomes-regulated lipid metabolism in tumorigenesis and cancer progression	32
Nefarious NTRK oncogenic fusions in pediatric sarcomas: Too many to Trk	32
Could IL-25 be a potential therapeutic target for intestinal inflammatory diseases?	30
Uncovering key mechanisms and intervention therapies in aging skin	30
Spatiotemporal dynamic regulation of the CX3CL1-CX3CR1 axis: A double-edged sword in the tumor immune microenvironment and new strategies for precision therapy	30
cPLA2 in musculoskeletal and autoimmune diseases: Molecular mechanisms and therapeutic insights	29
The intricate relationship between cytokines and galectins in immune modulation	29