OOIR: Observatory of International Research

Papers

(The TQCC of Cytokine & Growth Factor Reviews is 23. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system	991
SARS-CoV-2 infection: The role of cytokines in COVID-19 disease	808
Cytokine storm intervention in the early stages of COVID-19 pneumonia	356
COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons	298
IL-6: Relevance for immunopathology of SARS-CoV-2	221
The global impact of the coronavirus pandemic	198
Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes	130
SARS-CoV-2 Mutations and their Viral Variants	104
The relationship between bone marrow adipose tissue and bone metabolism in postmenopausal osteoporosis	95
The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies	89
The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved	82
The potential of JAK/STAT pathway inhibition by ruxolitinib in the treatment of COVID-19	78
SARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders	77
Understanding novel COVID-19: Its impact on organ failure and risk assessment for diabetic and cancer patients	70
Hallmarks of aging and immunosenescence: Connecting the dots	69
The Covid-19 pandemic in Denmark: Big lessons from a small country	64
A critical evaluation of glucocorticoids in the management of severe COVID-19	64
Mechanisms of NLRP3 priming in inflammaging and age related diseases	64
Is Toll-like receptor 4 involved in the severity of COVID-19 pathology in patients with cardiometabolic comorbidities?	60
Crosstalk between glucose metabolism, lactate production and immune response modulation	54
Applications of the regenerative capacity of platelets in modern medicine	52
Insulin as an immunomodulatory hormone	52
Semaphorins in health and disease	47
Receptor binding competition: A paradigm for regulating TGF-β family action	46
ALCAM/CD166: A pleiotropic mediator of cell adhesion, stemness and cancer progression	44

Crosstalk between ferroptosis and the epithelial-mesenchymal transition: Implications for inflammation and cancer therapy	44
SARS-CoV-2: Targeted managements and vaccine development	44
Growth differentiation factor-15 and its role in diabetes and cardiovascular disease	43
Chemokine networks modulating natural killer cell trafficking to solid tumors	43
Functions of FGFR2 corrupted by translocations in intrahepatic cholangiocarcinoma	43
Acute inflammation and pathogenesis of SARS-CoV-2 infection: Cannabidiol as a potential anti-inflammatory treatment?	40
SARS-CoV-2 infection and oxidative stress: Pathophysiological insight into thrombosis and therapeutic opportunities	39
S100A8/A9 in COVID-19 pathogenesis: Impact on clinical outcomes	38
Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia	38
Engineering and combining oncolytic measles virus for cancer therapy	37
Antiphospholipid antibodies and risk of post-COVID-19 vaccination thrombophilia: The straw that breaks the camel's back?	37
Biological functions and therapeutic opportunities of soluble cytokine receptors	36
Senescence in polyploid giant cancer cells: A road that leads to chemoresistance	36
A cytokine super cyclone in COVID-19 patients with risk factors: the therapeutic potential of BCG immunization	36
FGF/FGFR signaling: From lung development to respiratory diseases	35
The RNA binding protein SRSF1 is a master switch of gene expression and regulation in the immune system	35
Correlation between PD-1/PD-L1 expression and polarization in tumor-associated macrophages: A key player in tumor immunotherapy	34
The protective and pathogenic roles of CXCL17 in human health and disease: Potential in respiratory medicine	34
IL-36 in chronic inflammation and cancer	33
The immunosuppressive and pro-tumor functions of CCL18 at the tumor microenvironment	33
Scarless wound healing: Current insights from the perspectives of TGF-β, KGF-1, and KGF-2	33
Biological functions of NLRP3 inflammasome: A therapeutic target in inflammatory bowel disease	33
Selective inhibition of Tumor necrosis factor receptor-1 (TNFR1) for the treatment of autoimmune diseases	32
Cytokines in oncolytic virotherapy	32
Glycogen synthase kinase-3: A putative target to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic	32
IL-15 immunotherapy is a viable strategy for COVID-19	32
Secretory Leukocyte Protease Inhibitor (SLPI) in mucosal tissues: Protects against inflammation, but promotes cancer	31
An evaluation of the effects of probiotics on tumoral necrosis factor (TNF-α) signaling and gene expression	31
The involvement of TH17 cells in the pathogenesis of IBD	30
Granulocyte macrophage colony-stimulating factor has come of age: From a vaccine adjuvant to antiviral immunotherapy	30
Mechanisms of measles virus oncolytic immunotherapy	29
The determinant role of IL-6 in the establishment of inflammation leading to spontaneous preterm birth	29
The Coronavirus pandemic – 2022: Viruses, variants & vaccines	29
Cancer-associated fibroblasts: Vital suppressors of the immune response in the tumor microenvironment	28
Exercise tolls the bell for key mediators of low-grade inflammation in dysmetabolic conditions	27
Revisiting IRF1-mediated antiviral innate immunity	27
The evolving epidemiology of monkeypox virus	27
Principles of the activin receptor signaling pathway and its inhibition	25
Role of SARS-CoV-2 -induced cytokines and growth factors in coagulopathy and thromboembolism	24
Pro-angiogenic activity and vasculogenic mimicry in the tumor microenvironment by leptin in cancer	23
The cytokine interleukin-11 crucially links bone formation, remodeling and resorption	23
Asprosin, a novel pleiotropic adipokine implicated in fasting and obesity-related cardio-metabolic disease: Comprehensive review of preclinical and clinical evidence	23
Development of mRNA vaccines against respiratory syncytial virus (RSV)	23