OOIR: Observatory of International Research

Papers

(The H4-Index of Cytokine & Growth Factor Reviews is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Editorial Board	140
Unveiling cytokine charge disparity as a potential mechanism for immune regulation	136
Targeting the metabolism and immune system in pancreatic ductal adenocarcinoma: Insights and future directions	116
Macrophage-derived cytokines in pneumonia: Linking cellular immunology and genetics	109
COVID-19 as a mediator of interferon deficiency and hyperinflammation: Rationale for the use of JAK1/2 inhibitors in combination with interferon	105
Potential effects of HMGB1 on viral replication and virus infection-induced inflammatory responses: A promising therapeutic target for virus infection-induced inflammatory diseases	93
Navigating IL-6: From molecular mechanisms to therapeutic breakthroughs	89
COVID-19: From emerging variants to vaccination	77
Editorial Board	72
Editorial Board	71
Editorial Board	68
Proteomics analysis of circulating small extracellular vesicles: Focus on the contribution of EVs to tumor metabolism	65
Insights into IL-6/JAK/STAT3 signaling in the tumor microenvironment: Implications for cancer therapy	64
Participation of interferons in psoriatic inflammation	62
CDK4/6 inhibition in hormone receptor-positive/HER2-negative breast cancer: Biological and clinical aspects	62
Progranulinopathy: A diverse realm of disorders linked to progranulin imbalances	61
Gradients in the in vivo intestinal stem cell compartment and their in vitro recapitulation in mimetic platforms	58
Molecular mechanisms of regulation of IL-1 and its receptors	57
Epithelial-to-mesenchymal transition transcription factors: New strategies for mesenchymal tissue regeneration	54
Immuno-metabolic control of the balance between Th17-polarized and regulatory T-cells during HIV infection	51
The immunosuppressive and pro-tumor functions of CCL18 at the tumor microenvironment	50
Central role of Galectin-3 at the cross-roads of cardiac inflammation and fibrosis: Implications for heart failure and transplantation	49
Novel insights into neuroinflammatory mechanisms in traumatic brain injury: Focus on pattern recognition receptors as therapeutic targets	48
Pro-angiogenic activity and vasculogenic mimicry in the tumor microenvironment by leptin in cancer	47
Asprosin, a novel pleiotropic adipokine implicated in fasting and obesity-related cardio-metabolic disease: Comprehensive review of preclinical and clinical evidence	44

Exogenous drug-induced mouse models of atopic dermatitis	44
TGF-β mediated drug resistance in solid cancer	43
Immunosuppressive tumor microenvironment and uterine fibroids: Role in collagen synthesis	42
Current utilization of interferon alpha for the treatment of coronavirus disease 2019: A comprehensive review	42
Suppressor of cytokine signaling 6 in cancer development and therapy: Deciphering its emerging and suppressive roles	42
Chemokines and chemokine receptors: Insights from human disease and experimental models of helminthiasis	40
Scarless wound healing: Current insights from the perspectives of TGF-β, KGF-1, and KGF-2	37
Principles of the activin receptor signaling pathway and its inhibition	37
The cGAS-STING pathway: Post-translational modifications and functional implications in diseases	36
Exosomes as a modulator of immune resistance in human cancers	35
Neurotrophic factors and their receptors in lung development and implications in lung diseases	35
Tumor microenvironment, histone modifications, and myeloid-derived suppressor cells	35