OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Psychiatry is 74. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Quantitative magnetization transfer and g-ratio imaging of white matter myelin in early psychotic spectrum disorders	684
Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters	622
Activation of β2-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms	456
Psychedelics, psychosis, and the elusive notion of safety	434
Changes in cerebral connectivity and brain tissue pulsations with the antidepressant response to an equimolar mixture of oxygen and nitrous oxide: an MRI and ultrasound study	290
Mediating and moderating effects of plasma proteomic biomarkers on the association between poor oral health problems and brain white matter microstructural integrity: the UK Biobank study	260
Hyperactivity of subicular parvalbumin interneurons drives early amyloid pathology and cognitive deficits in Alzheimer’s disease	221
Interrelations between dopaminergic-, gabaergic- and glutamatergic neurotransmitters in antipsychotic-naïve psychosis patients and the association to initial treatment response	210
Microbial infection promotes amyloid pathology in a mouse model of Alzheimer’s disease via modulating γ-secretase	195
Correction: Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pa	184
Crif1 deficiency in dopamine neurons triggers early-onset parkinsonism	178
Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure	177
Disease clusters and their genetic determinants following a diagnosis of depression: analyses based on a novel three-dimensional disease network approach	161
Negative allosteric modulation of mGlu7 disrupts fear memory reconsolidation and glutamatergic signaling in rat and human brain tissue	159
Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health	157
The role of PPAR-γ in memory deficits induced by prenatal and lactation alcohol exposure in mice	156
Gene dosage effects of 22q11.2 copy number variants on in-vivo measures of white matter axonal density and dispersion	147
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome	146
The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder	146
Deciphering the influence of socioeconomic status on brain structure: insights from Mendelian randomization	140
Multivariate patterns linking brain microstructure to temperament and behavior in adolescent eating disorders	138
Dynorphin / kappa-opioid receptor regulation of excitation-inhibition balance toggles afferent control of prefrontal cortical circuits in a pathway-specific manner	135
Integration of valence and conflict processing through cellular-field interactions in human subgenual cingulate during emotional face processing in treatment-resistant depression	132
The alpha7 nicotinic acetylcholine receptor mediates network dysfunction in a mouse model of local amyloid pathology	132
Abatacept inhibits Th17 differentiation and mitigates α-synuclein-induced dopaminergic dysfunction in mice	128

Rare copy number variation in posttraumatic stress disorder	124
Sex differences in trajectories of cortical development in autistic children from 2–13 years of age	123
Exploring the impact of cognitive profiles on the response to magnetic seizure therapy and electroconvulsive therapy	123
Transcriptomic pathology of neocortical microcircuit cell types across psychiatric disorders	122
Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer’s disease through potentiating the function of extrasynaptic glycine receptors	122
Transcriptomic profiles in major depressive disorder: the role of immunometabolic and cell-cycle-related pathways in depression with different levels of inflammation	121
Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity	120
The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk	117
Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons	117
Mitochondrial health index correlates with plasma circulating cell-free mitochondrial DNA in bipolar disorder	116
MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention	112
Computational mechanisms of learning and forgetting differentiate affective and substance use disorders	112
A burden of rare copy number variants in obsessive-compulsive disorder	110
Neurophysiological correlates of ketamine-induced dissociative state in bipolar disorder: insights from real-world clinical settings	108
ASD mutations in the ciliary gene CEP41 impact development of projection neurons and interneurons in a human cortical organoid model	107
Multi-polygenic score prediction of mathematics, reading, and language abilities independent of general cognitive ability	106
Loss of Necdin causes social deficit and aberrant synaptic function through destabilization of SynGAP	104
Neurocognitive effects of stress: a metaparadigm perspective	104
Roles of the medial and lateral orbitofrontal cortex in major depression and its treatment	104
Tractography-based versus anatomical landmark-based targeting in vALIC deep brain stimulation for refractory obsessive-compulsive disorder	103
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures	103
Inactivation of hypocretin receptor-2 signaling in dopaminergic neurons induces hyperarousal and enhanced cognition but impaired inhibitory control	103
Maternal COVID-19 infection associated with offspring neurodevelopmental disorders	102
Associations between mosaic loss and schizophrenia or bipolar disorder of young age	101
NLRP3-mediated trained immunity of microglia is involved in the recurrence-like episode of depressive disorders	99
5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA	97
CLN5 deficiency impairs glucose uptake and uncovers PHGDH as a potential biomarker in Batten disease	96
Maternal stressors disrupt mouse placental proteome and fetal brain development in a sex-specific fashion through inflammation and oxidative stress	94
Shared genetic basis between reproductive behaviors and anxiety-related disorders	94
Age-related vulnerability of the human brain connectome	94
Rare coding variants as risk modifiers of the 22q11.2 deletion implicate postnatal cortical development in syndromic schizophrenia	93
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia	92
Transcriptomic and epigenomic consequences of heterozygous loss-of-function mutations in AKAP11, a shared risk gene for bipolar disorder and schizophrenia	91
Crosstalk between alcohol use disorder and obesity: two sides of the same coin?	89
Aberrant impulse control circuitry in obesity	88
Neurobiological subtypes of adolescent depression: a multimodal integration of morphometric similarity network and spatial transcriptomics	87
Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders	85
Stress-induced dysfunction of neurovascular astrocytes in the prefrontal cortex contributes to sex-dependent deficits in cognition and behavior	84
Global and local ancestry modulate APOE association with Alzheimer’s neuropathology and cognitive outcomes in an admixed sample	83
Melatonin: A potential nighttime guardian against Alzheimer’s	82
A higher dysregulation burden of brain DNA methylation in female patients implicated in the sex bias of Schizophrenia	80
Evaluation of Nav1.8 as a therapeutic target for Pitt Hopkins Syndrome	80
Heavy adolescent drinking makes the adult brain more vulnerable to ethanol by permanently altering the age-dependent interplay between alcohol, GIRK channels and activin	78
Differential impacts of germline and adult aggrecan knockout in PV+ neurons on perineuronal nets and PV+ neuronal function	77
De novo protein-coding gene variants in developmental stuttering	77
Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood–brain barrier function	76
A meta-analysis of genome-wide studies of resilience in the German population	75
Early-life microbiota dysbiosis as a link between Autism Spectrum Disorder and Parkinson’s Disease	74
Robust and replicable functional brain signatures of 22q11.2 deletion syndrome and associated psychosis: a deep neural network-based multi-cohort study	74
Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer’s disease	74