OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Psychiatry is 63. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-01-01 to 2025-01-01.)

Article	Citations
Reply to “Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review”	1502
Activation of β2-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms	798
Electric field distribution models in ECT research	382
Loss of liver X receptor β in astrocytes leads to anxiety-like behaviors via regulating synaptic transmission in the medial prefrontal cortex in mice	267
Are we getting closer to offering deep brain stimulation for treatment-resistant depression in clinical practice?	246
Novel epigenetic molecular therapies for imprinting disorders	206
Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders	186
Although serotonin is not a major player in depression, its precursor is	185
A causal association of ANKRD37 with human hippocampal volume	182
Cross-sectional and longitudinal neuroanatomical profiles of distinct clinical (adaptive) outcomes in autism	177
Perifornical area Urocortin-3 neuronal activation levels in response to foreign pups depends on physiological context	174
How to (not) decide about the motor vs psychomotor origin of psychomotor disturbances in depression	172
Microbial infection promotes amyloid pathology in a mouse model of Alzheimer’s disease via modulating γ-secretase	166
Rare copy number variation in posttraumatic stress disorder	161
Heparin treatment is associated with a delayed diagnosis of Alzheimer’s dementia in electronic health records from two large United States health systems	158
Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors	151
Cortical profiles of numerous psychiatric disorders and normal development share a common pattern	150
Sustained TNF signaling is required for the synaptic and anxiety-like behavioral response to acute stress	146
The acute phase protein lactoferrin is a key feature of Alzheimer’s disease and predictor of Aβ burden through induction of APP amyloidogenic processing	145
Top-down regulation of motivated behaviors via lateral septum sub-circuits	144
LHPP, a risk factor for major depressive disorder, regulates stress-induced depression-like behaviors through its histidine phosphatase activity	120
Cortical morphology in patients with the deficit and non-deficit syndrome of schizophrenia: a worldwide meta- and mega-analyses	109
Sex differences in methylphenidate-induced dopamine increases in ventral striatum	106
Self-management with alcohol over lifespan: psychological mechanisms, neurobiological underpinnings, and risk assessment	105
The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders	103

Aberrant impulse control circuitry in obesity	103
The effects of stimulant dose and dosing strategy on treatment outcomes in attention-deficit/hyperactivity disorder in children and adolescents: a meta-analysis	95
Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport	91
Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure	90
Cognitive performance protects against Alzheimer’s disease independently of educational attainment and intelligence	90
Dopamine transporter blockade during adolescence increases adult dopamine function, impulsivity, and aggression	89
Targeted therapy of cognitive deficits in fragile X syndrome	89
Rare coding variants as risk modifiers of the 22q11.2 deletion implicate postnatal cortical development in syndromic schizophrenia	89
Expanding the heuristic neurocircuit-based taxonomy to guide treatment for OCD: reply to the commentary “Probing the genetic and molecular correlates of connectome alterations in obsessive-compulsive	88
The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment	83
Ca2+-permeable AMPA receptors set the threshold for retrieval of drug memories	83
Microglial type I interferon signaling mediates chronic stress-induced synapse loss and social behavior deficits	83
Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility	83
Trans-ancestry epigenome-wide association meta-analysis of DNA methylation with lifetime cannabis use	82
Implications of parental stress on worsening of behavioral problems in children with autism during COVID-19 pandemic: “the spillover hypothesis”	79
Assessment of early neurocognitive functioning increases the accuracy of predicting chronic PTSD risk	78
Newly identified structures of trace-amine associated receptor-1 (TAAR1) will aid discovery of next generation neuropsychiatric drugs	77
Diversity of mechanism of action of psychotropic drugs in their anti-COVID-19 properties	77
In vivo tractography of human locus coeruleus—relation to 7T resting state fMRI, psychological measures and single subject validity	76
Whole-brain resting-state connectivity underlying impaired inhibitory control during early versus longer-term abstinence in cocaine addiction	76
A new suspect in the unsolved case of neuroinflammation in schizophrenia	76
The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder	75
Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c	72
Neurocognitive profiles of 22q11.2 and 16p11.2 deletions and duplications	72
Development of opioid-induced hyperalgesia depends on reactive astrocytes controlled by Wnt5a signaling	71
Resting mononuclear cell NR3C1 and SKA2 expression levels predict blunted cortisol reactivity to combat training stress among elite army cadets exposed to childhood adversity	70
Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure	69
An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function	67
Transcriptomics analysis of human iPSC-derived dopaminergic neurons reveals a novel model for sporadic Parkinson’s disease	66
Gestational epigenetic age and ADHD symptoms in childhood: a prospective, multi-cohort study	66
Sex dimorphism controls dysbindin-related cognitive dysfunctions in mice and humans with the contribution of COMT	65
Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder	65
Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus	65
Aβ1-6A2V(D) peptide, effective on Aβ aggregation, inhibits tau misfolding and protects the brain after traumatic brain injury	64
A burden of rare copy number variants in obsessive-compulsive disorder	64
Divergent time-varying connectivity of thalamic sub-regions characterizes clinical phenotypes and cognitive status in multiple sclerosis	64
Immunoglobulin genes expressed in lymphoblastoid cell lines discern and predict lithium response in bipolar disorder patients	63
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome	63
Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer’s disease through potentiating the function of extrasynaptic glycine receptors	63
A prediction model for electroconvulsive therapy effectiveness in patients with major depressive disorder from the Dutch ECT Consortium (DEC)	63
Effects of sleep on the glymphatic functioning and multimodal human brain network affecting memory in older adults	63