OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Psychiatry is 63. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)

Article	Citations
Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies	1133
The Amyloid-β Pathway in Alzheimer’s Disease	580
COVID-19 risk and outcomes in patients with substance use disorders: analyses from electronic health records in the United States	412
Diet and depression: exploring the biological mechanisms of action	300
The serotonin theory of depression: a systematic umbrella review of the evidence	283
The impact of quarantine on mental health status among general population in China during the COVID-19 pandemic	195
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative	192
The blood-brain barrier in aging and neurodegeneration	190
Prognostic value of depression and anxiety on breast cancer recurrence and mortality: a systematic review and meta-analysis of 282,203 patients	188
A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia	184
Prevalence of posttraumatic stress disorder after infectious disease pandemics in the twenty-first century, including COVID-19: a meta-analysis and systematic review	177
Association between antidepressant use and reduced risk of intubation or death in hospitalized patients with COVID-19: results from an observational study	174
Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability	153
The longitudinal associations of inflammatory biomarkers and depression revisited: systematic review, meta-analysis, and meta-regression	146
The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies	142
Treatment resistance in psychiatry: state of the art and new directions	140
Polysubstance use in the U.S. opioid crisis	138
Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research	137
Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor	130
A systematic review and meta-analysis of long term physical and mental sequelae of COVID-19 pandemic: call for research priority and action	128
Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications	125
The neuroendocrinology of stress: the stress-related continuum of chronic disease development	124
Gut microbiota modulates the inflammatory response and cognitive impairment induced by sleep deprivation	121
Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications	120
Oligodendrocyte lineage cells and depression	120

Association of inflammation with depression and anxiety: evidence for symptom-specificity and potential causality from UK Biobank and NESDA cohorts	120
Recognizing the importance of childhood maltreatment as a critical factor in psychiatric diagnoses, treatment, research, prevention, and education	117
Molecular pathways of major depressive disorder converge on the synapse	116
Changes in network centrality of psychopathology symptoms between the COVID-19 outbreak and after peak	112
Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology	103
Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine	96
Toward a neurocircuit-based taxonomy to guide treatment of obsessive–compulsive disorder	92
Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment	91
Disrupted intrinsic functional brain topology in patients with major depressive disorder	90
Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis	85
Mood stabilizers and/or antipsychotics for bipolar disorder in the maintenance phase: a systematic review and network meta-analysis of randomized controlled trials	84
A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action	84
Efficacy of neurostimulation across mental disorders: systematic review and meta-analysis of 208 randomized controlled trials	83
Individual deviations from normative models of brain structure in a large cross-sectional schizophrenia cohort	81
Behavioral, neuroanatomical, and molecular correlates of resilience and susceptibility to maternal immune activation	81
Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes	80
Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids	79
A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials	79
Does the human ventromedial prefrontal cortex support fear learning, fear extinction or both? A commentary on subregional contributions	77
Mechanisms of action of fluvoxamine for COVID-19: a historical review	77
Discontinuation of antidepressants after remission with antidepressant medication in major depressive disorder: a systematic review and meta-analysis	76
Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer’s disease: a longitudinal cohort study	74
Putting the “mental” back in “mental disorders”: a perspective from research on fear and anxiety	73
Appropriate exercise level attenuates gut dysbiosis and valeric acid increase to improve neuroplasticity and cognitive function after surgery in mice	72
Multivariate relationships between peripheral inflammatory marker subtypes and cognitive and brain structural measures in psychosis	72
Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of concept and mechanism study	71
The acid sphingomyelinase/ceramide system in COVID-19	70
Age-related immune alterations and cerebrovascular inflammation	70
AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia	69
Multi-omics analyses of serum metabolome, gut microbiome and brain function reveal dysregulated microbiota-gut-brain axis in bipolar depression	69
Glutamatergic and GABAergic metabolite levels in schizophrenia-spectrum disorders: a meta-analysis of 1H-magnetic resonance spectroscopy studies	69
Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids	69
Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts	68
Clinical prediction models in psychiatry: a systematic review of two decades of progress and challenges	67
A systematic review and meta-analysis on the prevalence of stigma in infectious diseases, including COVID-19: a call to action	66
Role of phosphodiesterases in the pathophysiology of neurodevelopmental disorders	65
Dysregulation of mitochondrial dynamics, mitophagy and apoptosis in major depressive disorder: Does inflammation play a role?	63
Incidence, prevalence, and global burden of autism spectrum disorder from 1990 to 2019 across 204 countries	63