OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Psychiatry is 75. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Correction: Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pa	530
Electric field distribution models in ECT research	433
Integration of valence and conflict processing through cellular-field interactions in human subgenual cingulate during emotional face processing in treatment-resistant depression	384
Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons	346
Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters	286
Divergent time-varying connectivity of thalamic sub-regions characterizes clinical phenotypes and cognitive status in multiple sclerosis	268
Rare copy number variation in posttraumatic stress disorder	236
Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful extinction of fear	220
Changes in cerebral connectivity and brain tissue pulsations with the antidepressant response to an equimolar mixture of oxygen and nitrous oxide: an MRI and ultrasound study	206
Brain regions susceptible to alpha-synuclein spreading	168
Global and local ancestry modulate APOE association with Alzheimer’s neuropathology and cognitive outcomes in an admixed sample	166
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome	159
Activation of β2-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms	159
Maternal COVID-19 infection associated with offspring neurodevelopmental disorders	158
Abatacept inhibits Th17 differentiation and mitigates α-synuclein-induced dopaminergic dysfunction in mice	140
Sex differences in trajectories of cortical development in autistic children from 2–13 years of age	137
Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders	136
Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity	135
Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer’s disease through potentiating the function of extrasynaptic glycine receptors	129
Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure	127
Multivariate patterns linking brain microstructure to temperament and behavior in adolescent eating disorders	122
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia	122
5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA	118
Quantitative magnetization transfer and g-ratio imaging of white matter myelin in early psychotic spectrum disorders	115
Deciphering the influence of socioeconomic status on brain structure: insights from Mendelian randomization	114

CLN5 deficiency impairs glucose uptake and uncovers PHGDH as a potential biomarker in Batten disease	113
Transcriptomic profiles in major depressive disorder: the role of immunometabolic and cell-cycle-related pathways in depression with different levels of inflammation	112
Transcriptomic pathology of neocortical microcircuit cell types across psychiatric disorders	107
Widespread choroid plexus contamination in sampling and profiling of brain tissue	107
Mitochondrial health index correlates with plasma circulating cell-free mitochondrial DNA in bipolar disorder	106
Anti-depressive-like behaviors of APN KO mice involve Trkb/BDNF signaling related neuroinflammatory changes	105
Rare coding variants as risk modifiers of the 22q11.2 deletion implicate postnatal cortical development in syndromic schizophrenia	105
Disease clusters and their genetic determinants following a diagnosis of depression: analyses based on a novel three-dimensional disease network approach	104
Dynorphin / kappa-opioid receptor regulation of excitation-inhibition balance toggles afferent control of prefrontal cortical circuits in a pathway-specific manner	104
Unconsidered issues of measurement noninvariance in biological psychiatry: A focus on biological phenotypes of psychopathology	103
Aberrant impulse control circuitry in obesity	102
The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders	101
MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention	98
Crif1 deficiency in dopamine neurons triggers early-onset parkinsonism	97
The role of PPAR-γ in memory deficits induced by prenatal and lactation alcohol exposure in mice	97
Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility	96
Multi-polygenic score prediction of mathematics, reading, and language abilities independent of general cognitive ability	95
Inactivation of hypocretin receptor-2 signaling in dopaminergic neurons induces hyperarousal and enhanced cognition but impaired inhibitory control	93
Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear	92
Transcriptomic and epigenomic consequences of heterozygous loss-of-function mutations in AKAP11, a shared risk gene for bipolar disorder and schizophrenia	92
Microbial infection promotes amyloid pathology in a mouse model of Alzheimer’s disease via modulating γ-secretase	92
Stress-induced dysfunction of neurovascular astrocytes in the prefrontal cortex contributes to sex-dependent deficits in cognition and behavior	90
The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder	89
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures	89
Neurobiological subtypes of adolescent depression: a multimodal integration of morphometric similarity network and spatial transcriptomics	89
Neurophysiological correlates of ketamine-induced dissociative state in bipolar disorder: insights from real-world clinical settings	89
Shared genetic basis between reproductive behaviors and anxiety-related disorders	88
Enhancing GluN2A-type NMDA receptors impairs long-term synaptic plasticity and learning and memory	88
A burden of rare copy number variants in obsessive-compulsive disorder	88
Mediating and moderating effects of plasma proteomic biomarkers on the association between poor oral health problems and brain white matter microstructural integrity: the UK Biobank study	86
Tractography-based versus anatomical landmark-based targeting in vALIC deep brain stimulation for refractory obsessive-compulsive disorder	85
Neurocognitive effects of stress: a metaparadigm perspective	85
Structure-function relationships of the disease-linked A218T oxytocin receptor variant	85
Melatonin: A potential nighttime guardian against Alzheimer’s	84
Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons	82
Loss of Necdin causes social deficit and aberrant synaptic function through destabilization of SynGAP	82
Roles of the medial and lateral orbitofrontal cortex in major depression and its treatment	81
Age-related vulnerability of the human brain connectome	81
Structural gray matter differences in Problematic Usage of the Internet: a systematic review and meta-analysis	81
The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk	81
What genes are differentially expressed in individuals with schizophrenia? A systematic review	81
Peripheral inflammation is associated with micro-structural and functional connectivity changes in depression-related brain networks	81
Diverging asymmetry of intrinsic functional organization in autism	80
Maternal stressors disrupt mouse placental proteome and fetal brain development in a sex-specific fashion through inflammation and oxidative stress	80
Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer’s disease	79
Paternal nicotine taking elicits heritable sex-specific phenotypes that are mediated by hippocampal Satb2	79
Melancholia as psychalgia: the integration of psychophysiological theory and psychopathologic observation in the mid-19th century	78
11C-UCB-J PET imaging is consistent with lower synaptic density in autistic adults	76
Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood–brain barrier function	76
Replication of a neuroimaging biomarker for striatal dysfunction in psychosis	75

Shared and unique transcriptomic signatures of antidepressant and probiotics action in the mammalian brain