OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Psychiatry is 64. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies	1321
The Amyloid-β Pathway in Alzheimer’s Disease	691
The serotonin theory of depression: a systematic umbrella review of the evidence	329
Diet and depression: exploring the biological mechanisms of action	324
The blood-brain barrier in aging and neurodegeneration	219
A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia	217
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative	203
The impact of quarantine on mental health status among general population in China during the COVID-19 pandemic	200
Prevalence of posttraumatic stress disorder after infectious disease pandemics in the twenty-first century, including COVID-19: a meta-analysis and systematic review	182
Association between antidepressant use and reduced risk of intubation or death in hospitalized patients with COVID-19: results from an observational study	177
Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability	166
Treatment resistance in psychiatry: state of the art and new directions	161
A systematic review and meta-analysis of long term physical and mental sequelae of COVID-19 pandemic: call for research priority and action	156
The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies	155
Polysubstance use in the U.S. opioid crisis	149
The neuroendocrinology of stress: the stress-related continuum of chronic disease development	145
Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications	141
Molecular pathways of major depressive disorder converge on the synapse	141
Association of inflammation with depression and anxiety: evidence for symptom-specificity and potential causality from UK Biobank and NESDA cohorts	137
Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor	137
Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications	136
Gut microbiota modulates the inflammatory response and cognitive impairment induced by sleep deprivation	136
Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment	134
Recognizing the importance of childhood maltreatment as a critical factor in psychiatric diagnoses, treatment, research, prevention, and education	131
Oligodendrocyte lineage cells and depression	126

Disrupted intrinsic functional brain topology in patients with major depressive disorder	109
Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology	107
Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine	103
Toward a neurocircuit-based taxonomy to guide treatment of obsessive–compulsive disorder	102
Efficacy of neurostimulation across mental disorders: systematic review and meta-analysis of 208 randomized controlled trials	97
Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes	96
A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action	95
Mood stabilizers and/or antipsychotics for bipolar disorder in the maintenance phase: a systematic review and network meta-analysis of randomized controlled trials	94
Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis	91
Behavioral, neuroanatomical, and molecular correlates of resilience and susceptibility to maternal immune activation	90
A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials	89
Multi-omics analyses of serum metabolome, gut microbiome and brain function reveal dysregulated microbiota-gut-brain axis in bipolar depression	84
Appropriate exercise level attenuates gut dysbiosis and valeric acid increase to improve neuroplasticity and cognitive function after surgery in mice	83
Mechanisms of action of fluvoxamine for COVID-19: a historical review	83
Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of concept and mechanism study	83
Multivariate relationships between peripheral inflammatory marker subtypes and cognitive and brain structural measures in psychosis	78
Does the human ventromedial prefrontal cortex support fear learning, fear extinction or both? A commentary on subregional contributions	78
Age-related immune alterations and cerebrovascular inflammation	77
Role of phosphodiesterases in the pathophysiology of neurodevelopmental disorders	77
AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia	76
Dysregulation of mitochondrial dynamics, mitophagy and apoptosis in major depressive disorder: Does inflammation play a role?	76
Glutamatergic and GABAergic metabolite levels in schizophrenia-spectrum disorders: a meta-analysis of 1H-magnetic resonance spectroscopy studies	76
Clinical prediction models in psychiatry: a systematic review of two decades of progress and challenges	76
Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts	76
Mitophagy in Alzheimer’s disease: Molecular defects and therapeutic approaches	75
Incidence, prevalence, and global burden of autism spectrum disorder from 1990 to 2019 across 204 countries	75
The acid sphingomyelinase/ceramide system in COVID-19	72
A systematic review and meta-analysis on the prevalence of stigma in infectious diseases, including COVID-19: a call to action	70
Pharmacological treatment for bipolar mania: a systematic review and network meta-analysis of double-blind randomized controlled trials	67
Genetics of glutamate and its receptors in autism spectrum disorder	67
Brain cells derived from Alzheimer’s disease patients have multiple specific innate abnormalities in energy metabolism	66
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?	66
The synapse as a treatment avenue for Alzheimer’s Disease	65
Alzheimer’s disease profiled by fluid and imaging markers: tau PET best predicts cognitive decline	65
Human cerebral organoids establish subcortical projections in the mouse brain after transplantation	65
Associations of family income with cognition and brain structure in USA children: prevention implications	65
The extracellular matrix and perineuronal nets in memory	65
Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis, and expression of longevity gene Klotho	64
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein	64