OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Psychiatry is 74. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Quantitative magnetization transfer and g-ratio imaging of white matter myelin in early psychotic spectrum disorders	670
Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters	603
Activation of β2-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms	440
Psychedelics, psychosis, and the elusive notion of safety	421
Crosstalk between alcohol use disorder and obesity: two sides of the same coin?	282
Mitochondrial health index correlates with plasma circulating cell-free mitochondrial DNA in bipolar disorder	251
Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer’s disease through potentiating the function of extrasynaptic glycine receptors	212
Changes in cerebral connectivity and brain tissue pulsations with the antidepressant response to an equimolar mixture of oxygen and nitrous oxide: an MRI and ultrasound study	203
Neurocognitive effects of stress: a metaparadigm perspective	193
Computational mechanisms of learning and forgetting differentiate affective and substance use disorders	178
Mediating and moderating effects of plasma proteomic biomarkers on the association between poor oral health problems and brain white matter microstructural integrity: the UK Biobank study	176
Hyperactivity of subicular parvalbumin interneurons drives early amyloid pathology and cognitive deficits in Alzheimer’s disease	170
MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention	155
Interrelations between dopaminergic-, gabaergic- and glutamatergic neurotransmitters in antipsychotic-naïve psychosis patients and the association to initial treatment response	155
Microbial infection promotes amyloid pathology in a mouse model of Alzheimer’s disease via modulating γ-secretase	151
Correction: Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pa	148
Crif1 deficiency in dopamine neurons triggers early-onset parkinsonism	143
Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity	140
Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure	139
Disease clusters and their genetic determinants following a diagnosis of depression: analyses based on a novel three-dimensional disease network approach	138
Negative allosteric modulation of mGlu7 disrupts fear memory reconsolidation and glutamatergic signaling in rat and human brain tissue	136
Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health	136
The role of PPAR-γ in memory deficits induced by prenatal and lactation alcohol exposure in mice	133
Aberrant impulse control circuitry in obesity	130
Gene dosage effects of 22q11.2 copy number variants on in-vivo measures of white matter axonal density and dispersion	128

Loss of Necdin causes social deficit and aberrant synaptic function through destabilization of SynGAP	126
The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder	122
Transcriptomic pathology of neocortical microcircuit cell types across psychiatric disorders	119
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome	118
Deciphering the influence of socioeconomic status on brain structure: insights from Mendelian randomization	117
Multivariate patterns linking brain microstructure to temperament and behavior in adolescent eating disorders	117
Integration of valence and conflict processing through cellular-field interactions in human subgenual cingulate during emotional face processing in treatment-resistant depression	116
The alpha7 nicotinic acetylcholine receptor mediates network dysfunction in a mouse model of local amyloid pathology	116
Dynorphin / kappa-opioid receptor regulation of excitation-inhibition balance toggles afferent control of prefrontal cortical circuits in a pathway-specific manner	116
Abatacept inhibits Th17 differentiation and mitigates α-synuclein-induced dopaminergic dysfunction in mice	113
Rare copy number variation in posttraumatic stress disorder	112
Exploring the impact of cognitive profiles on the response to magnetic seizure therapy and electroconvulsive therapy	110
Inactivation of hypocretin receptor-2 signaling in dopaminergic neurons induces hyperarousal and enhanced cognition but impaired inhibitory control	109
Stress-induced dysfunction of neurovascular astrocytes in the prefrontal cortex contributes to sex-dependent deficits in cognition and behavior	107
Sex differences in trajectories of cortical development in autistic children from 2–13 years of age	105
Multi-polygenic score prediction of mathematics, reading, and language abilities independent of general cognitive ability	104
Shared genetic basis between reproductive behaviors and anxiety-related disorders	102
Rare coding variants as risk modifiers of the 22q11.2 deletion implicate postnatal cortical development in syndromic schizophrenia	101
Maternal stressors disrupt mouse placental proteome and fetal brain development in a sex-specific fashion through inflammation and oxidative stress	101
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia	100
NLRP3-mediated trained immunity of microglia is involved in the recurrence-like episode of depressive disorders	100
Associations between mosaic loss and schizophrenia or bipolar disorder of young age	100
5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA	99
Global and local ancestry modulate APOE association with Alzheimer’s neuropathology and cognitive outcomes in an admixed sample	97
CLN5 deficiency impairs glucose uptake and uncovers PHGDH as a potential biomarker in Batten disease	97
The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk	97
Neurophysiological correlates of ketamine-induced dissociative state in bipolar disorder: insights from real-world clinical settings	96
Age-related vulnerability of the human brain connectome	94
Roles of the medial and lateral orbitofrontal cortex in major depression and its treatment	92
Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility	91
Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons	90
A burden of rare copy number variants in obsessive-compulsive disorder	90
Transcriptomic and epigenomic consequences of heterozygous loss-of-function mutations in AKAP11, a shared risk gene for bipolar disorder and schizophrenia	89
Neurobiological subtypes of adolescent depression: a multimodal integration of morphometric similarity network and spatial transcriptomics	88
Tractography-based versus anatomical landmark-based targeting in vALIC deep brain stimulation for refractory obsessive-compulsive disorder	87
Melatonin: A potential nighttime guardian against Alzheimer’s	86
Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders	86
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures	82
Transcriptomic profiles in major depressive disorder: the role of immunometabolic and cell-cycle-related pathways in depression with different levels of inflammation	81
Shared and unique transcriptomic signatures of antidepressant and probiotics action in the mammalian brain	81
Maternal COVID-19 infection associated with offspring neurodevelopmental disorders	81
Evaluation of Nav1.8 as a therapeutic target for Pitt Hopkins Syndrome	78
Replication of a neuroimaging biomarker for striatal dysfunction in psychosis	77
Case-control study of neuropsychiatric symptoms in electronic health records following COVID-19 hospitalization in 2 academic health systems	77
A higher dysregulation burden of brain DNA methylation in female patients implicated in the sex bias of Schizophrenia	76
The oxytocin system mediates behavioral and neurobiological alterations associated with early adversity	75
De novo protein-coding gene variants in developmental stuttering	75
Heavy adolescent drinking makes the adult brain more vulnerable to ethanol by permanently altering the age-dependent interplay between alcohol, GIRK channels and activin	75
11C-UCB-J PET imaging is consistent with lower synaptic density in autistic adults	74
Differential impacts of germline and adult aggrecan knockout in PV+ neurons on perineuronal nets and PV+ neuronal function	74