OOIR: Observatory of International Research

Papers

(The TQCC of International Journal of Biochemistry & Cell Biology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Editorial Board	70
Corrigendum to “Dual blockade of the A1 and A2A adenosine receptor prevents amyloid beta toxicity in neuroblastoma cells exposed to aluminum chloride” [Int. J. Biochem. Cell Biol. 54 (2014) 122–136]	61
Targeting miR-133-3p via Mesenchymal Stem Cells-Derived Exosomes as a Novel Cell-Free Therapy for Testosterone-Induced Benign Prostatic Hyperplasia	46
Hematopoietic stem cell conditioned media induces apoptosis in colorectal cancer stem cells via dysregulation of HSP90 and 26S proteasome system	46
NPM1 promotes cell proliferation by targeting PRDX6 in colorectal cancer	38
The role of α7 nicotinic acetylcholine receptors in post-acute sequelae of covid-19	36
The role of TRP channels in lung fibrosis: Mechanisms and therapeutic potential	32
CENPL accelerates cell proliferation, cell cycle, apoptosis, and glycolysis via the MEK1/2-ERK1/2 pathway in hepatocellular carcinoma	32
Imaging nanoscale axial dynamics at the basal plasma membrane	30
A modified model of PANoptosisto identify prognosis and immunotherapy response in bladder cancer	29
Parsing the effect of co-culture with brain organoids on Diffuse Intrinsic Pontine Glioma (DIPG) using quantitative proteomics	27
SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline	26
CORE at the boundary of stress resistance and longevity	25
CAPRIN1/TYMS/MTHFD2 axis promotes EMT process in nasopharyngeal carcinoma development	25
Dopamine D1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior, and neurophysiology	25
Editorial Board	24
Corrigendum to “GOLGI: cancer cell fate control” [Int. J. Biochem. Cell Biol. 145 (2022) 106174]	23
Wherefore Art Tau? Functional importance of site-specific tau phosphorylation in diverse subcellular domains	23
Retraction notice to “Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer” [Int. J. Biochem. Cell Biol. 116 (2019) 105617]	22
Corrigendum to “Inhibition of M2 macrophage-mediated mesenchymal stem cell migration: Boldine attenuates elbow heterotopic ossification” [Int. J. Biochem. Cell Biol. 185 (2025) 106787]	22
Transcriptional and post-transcriptional mechanisms that regulate the genetic program in Zika virus-infected macrophages	21
Neurotensin contributes to cholestatic liver disease potentially modulating matrix metalloprotease-7	21
Cancer: Phosphodiesterase type 4C (PDE4C), the forgotten subfamily as a therapeutic target	21
From mitochondria to cells to humans: Targeting bioenergetics in aging and disease	20
Editorial Board	20

Editorial Board	20
Functional inhibition of RECQL5 helicase elicits non-homologous end joining response and sensitivity of breast cancers to PARP inhibitor	20
Notum leads to potential pro-survival of OSCC through crosstalk between Shh and Wnt/β-catenin signaling via p-GSK3β	18
Tumor-derived exosomal ICAM1 promotes bone metastasis of triple-negative breast cancer by inducing CD8+ T cell exhaustion	17
The functional significance of circRNA/miRNA/mRNA interactions as a regulatory network in lung cancer biology	16
Cofilin is a key regulator of oxidative stress-induced intercellular tunneling nanotubes formation	16
Microtubules and cardiovascular diseases: insights into pathology and therapeutic strategies	16
27P silk bioactive peptides mediate multifaceted regulation of collagen and support balance in fibroblast subpopulations	16
Editorial Board	16
Advances in the application of fluorescence correlation spectroscopy to study detergent purified and encapsulated membrane proteins	16
Priming human bone marrow-derived mesenchymal stromal cells with signaling modifiers boosts their functionality: Potential application in regenerative therapies	15
Regulatory role of AMPK/Nrf2 signaling pathway in sevoflurane-enhanced intestinal protection against ischemia-reperfusion injury	14
Disulfiram/copper induces BAK-mediated caspase-independent apoptosis in MCF-7 cells	14
Mitochondrial homeostasis and their impact on gastric carcinoma	14
Purinosomes and lysosomes interact to maintain the purine pools	14
2.5D Traction Force Microscopy: Imaging three-dimensional cell forces at interfaces and biological applications	14
The divergent roles of exosomes in kidney diseases: Pathogenesis, diagnostics, prognostics and therapeutics	14
Corrigendum to “ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a Rac1- driven ROS production” [Int. J. Biochem. Mol. Bio. 164 (2023) 106474–106484]	14
The role of autophagy in intervertebral disc degeneration and the regulation mechanism of AP-2α on autophagy	14
The role of neutrophils in antibody-driven autoimmune cytopenias	14
Therapeutic potential of TIM-3 inhibition in cancer, viral infections, and autoimmune disorders	14
Adipose improves muscular atrophy caused by Sirtuin1 deficiency by promoting mitochondria synthesis	13
Retraction notice to “Coordinated involvement of cathepsins S, D and cystatin C in the commitment of hematopoietic stem cells to dendritic cells” [Int. J. Biochem. Cell Biol. 43 (2011) 775–783]	13
The role of nicotinic acetylcholine receptors in the pathophysiology and pharmacotherapy of autism spectrum disorder: Focus on α7 nicotinic receptors	13
UHRF1 poly-auto-ubiquitination induced by the anti-cancer drug, thymoquinone, is involved in the DNA repair machinery recruitment.	13
Trehalose induces B cell autophagy to alleviate myocardial injury via the AMPK/ULK1 signalling pathway in acute viral myocarditis induced by Coxsackie virus B3	13
A platinum(II) complex HY1-Pt overcomes cisplatin-induced resistance and attenuates metastasis of epithelial ovarian cancer by cancer cell stemness inhibition	13
The mechanism underlying the TC-G 1008 rescue of reactive oxygen species (ROS)-induced osteoblast apoptosis by the upregulation of peroxiredoxin 1	13
Immunosenescence and macrophages: From basics to therapeutics	13
Overexpression of PBX1 attenuates oxidative stress and apoptosis in diabetic cardiomyopathy by transcriptionally inhibiting TXNIP	12
Editorial Board	12
Chromobox protein homolog 7 (CBX7) deficiency inhibits osteoblast ferroptosis by activating the Nrf2 function in type 2 diabetic osteoporosis	12
Editorial Board	12
Editorial Board	12
Modulatory effects of exogenous estradiol during endotoxemia	12
SPDYE3 promotes cell cycle and LUSC progression by regulating the CDC25C/CDK1 pathway	12
Common dysmorphic oocytes and embryos in assisted reproductive technology laboratory in association with gene alternations	11
Editorial Board	11
Editorial Board	11
RNA-based logic for selective protein expression in senescent cells	10
YAP upregulates AMPKα1 to induce cancer cell senescence	10
Epigenetic regulation of hepatocellular carcinoma progression: MicroRNAs as therapeutic, diagnostic and prognostic factors	10
Roles of Syndecan-4 in cardiac injury and repair	10
METTL5-mediated m6A modification of SLC7A11 promotes cervical cancer by inhibiting ferroptosis	10
Naringenin nanoparticles targeting cyclin B1 suppress the progression of rheumatoid arthritis-associated lung cancer by inhibiting fibroblast-to-myofibroblast transition	10
Regulator of G protein signaling 2 is inhibited by hypoxia-inducible factor-1α/E1A binding protein P300 complex upon hypoxia in human preeclampsia	9
Epibrassinolide impaired colon tumor progression and induced autophagy in SCID mouse xenograft model via acting on cell cycle progression without affecting endoplasmic reticulum stress observed in vit	9
Mutations in the SLC35C1 gene, contributing to significant differences in fucosylation patterns, may underlie the diverse phenotypic manifestations observed in leukocyte adhesion deficiency type II pa	9
Syndecan-2 positively regulates Wnt/β-catenin signaling in breast cancer cells	9
Pathological implications of cellular stress in cardiovascular diseases	9

PLA inhibits TNF-α-induced PANoptosis of prostate cancer cells through metabolic reprogramming	9
ITCH inhibits alkaliptosis in human pancreatic cancer cells through YAP1-dependent SLC16A1 activation	9
Free radicals: Relationship to Human Diseases and Potential Therapeutic applications	9
Editorial Board	9
PIAS1 S510G variant acts as a genetic modifier of spinocerebellar ataxia type 3 by selectively impairing mutant ataxin-3 proteostasis	9
Melatonin alleviates endoplasmic reticulum stress and its mediated inflammation in adipocytes via the PER1/ATF6 signal	9
Corrigendum to “Diazepam enhances melanogenesis, melanocyte dendricity and melanosome transport via the PBR/cAMP/PKA pathway” [Int. J. Biochem. Cell Biol. 116 (2019) 105620]	9
Tamoxifen upregulates the peroxisomal β-oxidation enzyme Enoyl CoA hydratase and 3-hydroxyacyl CoA hydratase ameliorating hepatic lipid accumulation in mice	9
Role of hypoxia on microRNA-dependant regulation of HGFA – HGF – c-Met signalling pathway in human progenitor and mature endothelial cells	9
Talin mechanotransduction in disease	9
MLN4924 Suppresses head and neck squamous cell carcinoma progression by inactivating the mTOR signaling pathway via the NEDD8/CUL4/TSC2 axis	9
5'tiRNA-33-CysACA-1 promotes septic cardiomyopathy by targeting PGC-1α-mediated mitochondrial biogenesis	9
Abemaciclib-induced epithelial-mesenchymal transition mediated by cyclin-dependent kinase 4/6 independent of cell cycle arrest pathway	9
ALDOC regulated the biological function and immune infiltration of gastric cancer cells	9
Association of long non-coding RNA in lipid metabolism: Implications in leukemia	9
Mn2+ enhances phagocytosis of macrophages against Staphylococcus aureus by regulating autophagy	8
miR-320 regulates myogenesis by targeting growth factor receptor-bound protein-2 and ameliorates myotubes atrophy	8
LARP4A and LARP4B in cancer: The new kids on the block	8
Corrigendum to “ABAT targeted by miR-183-5p regulates cell functions in liver cancer” [Int. J. Biochem. Cell Biol. 141 (2021) 106116]	8
Editorial Board	8
An intact zinc finger motif of the C1B domain is critical for stability and activity of diacylglycerol kinase-ε	8
Editorial Board	8
AKT2 deficiency alleviates doxorubicin-induced cardiac injury via alleviating oxidative stress in cardiomyocytes	8
Inhibition of M2 macrophage-mediated mesenchymal stem cell migration: Boldine attenuates elbow heterotopic ossification	8
Characterizing the role of extracellular domain in GLP-1R biased agonism	8
PARP1 controls the transcription of CD24 by ADP-ribosylating the RNA helicase DDX5 in pancreatic cancer	8
Editorial Board	8
The potential regulation of the miR-17–92a cluster by miR-21	8
Tumor-derived microparticles promoted M2-like macrophages polarization to stimulate osteosarcoma progression	8
Roles of lipid metabolism and its regulatory mechanism in idiopathic pulmonary fibrosis: A review	7
IL-22 relieves hepatic ischemia-reperfusion injury by inhibiting mitochondrial apoptosis based on the activation of STAT3	7
Single-cell sequencing reveals the antifibrotic effects of YAP/TAZ in systemic sclerosis	7
Editorial Board	7
TRPM8 affects relative “cooling and heating” of subcellular organelles in microglia in a context-dependent manner	7
Single-cell transcriptomics and metabolomics reveal the potential role of ASRGL1 in metabolic reprogramming and invasion of nasopharyngeal carcinoma cells	7
Development of a deep learning-based model to diagnose mixed-type gastric cancer accurately	7
The duplexity of unconventional T cells in cancer	7
Adipose tissue macrophages-derived exosomal MiR-500a-5p under high glucose promotes adipocytes inflammation by suppressing Nrf2 expression	7
Function of connexin 43 and RhoA/LIMK2/Cofilin signaling pathway in transient changes of contraction and dilation of human umbilical arterial smooth muscle cells	7
The use of serotonin type 7 receptor antagonists as a pharmacological intervention in chronic stress. Insights from animal studies	7
Melatonin protects Leydig cells from HT-2 toxin-induced ferroptosis and apoptosis via glucose-6-phosphate dehydrogenase/glutathione -dependent pathway	7
Classical psychedelics’ action on brain monoaminergic systems	7
Identify key genes and biological processes participated in obesity-related cancer based on studying 12 cancers	7
Ultrasound-guided Manual Vacuum Aspiration is an optimal method for obtaining products of conception from early pregnancy loss for cytogenetic testing	7
Research and application of direct current in medicine: From cellular and molecular mechanisms to clinical application in ophthalmology	7
Xiaoyou decoction suppresses cervical precancerous lesions through the activation of cellular autophagy and the upregulation of p53 expression	7
The E3 ubiquitin ligase SCF (FBXW10)-mediated LATS2 degradation regulates angiogenesis and liver metastasis in colorectal cancer	7
Visualizing, quantifying and mapping chromatin remodelers at work with single-molecule and single-cell imaging	7
To what extent may aminochrome increase the vulnerability of dopaminergic neurons in the context of Parkinson's disease	7
E2F1-mediated ectopic expression of PP1A promotes breast cancer progression via activation of YAP1	7
Enhancement of wound healing in diabetic mice by topical use of a peptide-ionic liquid conjugate	7
Influence of the ERK/CHGB pathway in breast cancer progression under chronic stress	7