OOIR: Observatory of International Research

Papers

(The TQCC of International Journal of Biochemistry & Cell Biology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Editorial Board	90
Corrigendum to “Dual blockade of the A1 and A2A adenosine receptor prevents amyloid beta toxicity in neuroblastoma cells exposed to aluminum chloride” [Int. J. Biochem. Cell Biol. 54 (2014) 122–136]	74
CENPL accelerates cell proliferation, cell cycle, apoptosis, and glycolysis via the MEK1/2-ERK1/2 pathway in hepatocellular carcinoma	55
The role of α7 nicotinic acetylcholine receptors in post-acute sequelae of covid-19	51
The role of TRP channels in lung fibrosis: Mechanisms and therapeutic potential	42
Time-resolved proteomics reveals five modules of stress granule disassembly and identifies SYNCRIP as a late-phase clearance factor	38
Targeting miR-133-3p via mesenchymal stem cells-derived exosomes as a novel cell-free therapy for testosterone-induced benign prostatic hyperplasia	38
Imaging nanoscale axial dynamics at the basal plasma membrane	34
Hematopoietic stem cell conditioned media induces apoptosis in colorectal cancer stem cells via dysregulation of HSP90 and 26S proteasome system	33
A modified model of PANoptosisto identify prognosis and immunotherapy response in bladder cancer	31
SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline	31
CAPRIN1/TYMS/MTHFD2 axis promotes EMT process in nasopharyngeal carcinoma development	27
Transcriptional and post-transcriptional mechanisms that regulate the genetic program in Zika virus-infected macrophages	27
Wherefore Art Tau? Functional importance of site-specific tau phosphorylation in diverse subcellular domains	26
CORE at the boundary of stress resistance and longevity	25
Editorial Board	24
Corrigendum to “GOLGI: cancer cell fate control” [Int. J. Biochem. Cell Biol. 145 (2022) 106174]	24
Cancer: Phosphodiesterase type 4C (PDE4C), the forgotten subfamily as a therapeutic target	24
Retraction notice to “Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer” [Int. J. Biochem. Cell Biol. 116 (2019) 105617]	23
Parsing the effect of co-culture with brain organoids on Diffuse Intrinsic Pontine Glioma (DIPG) using quantitative proteomics	23
Corrigendum to “Inhibition of M2 macrophage-mediated mesenchymal stem cell migration: Boldine attenuates elbow heterotopic ossification” [Int. J. Biochem. Cell Biol. 185 (2025) 106787]	23
Tumor-derived exosomal ICAM1 promotes bone metastasis of triple-negative breast cancer by inducing CD8+ T cell exhaustion	22
Functional inhibition of RECQL5 helicase elicits non-homologous end joining response and sensitivity of breast cancers to PARP inhibitor	22
Neurotensin contributes to cholestatic liver disease potentially modulating matrix metalloprotease-7	22
Dihydroorotate dehydrogenase: A multifunctional target in cancer, infectious diseases, and immune disorders	22

Editorial Board	22
Editorial Board	20
Ferroptosis and cuproptosis in gastric cancer: Mechanisms, roles, and potential Interplay	18
Notum leads to potential pro-survival of OSCC through crosstalk between Shh and Wnt/β-catenin signaling via p-GSK3β	17
From mitochondria to cells to humans: Targeting bioenergetics in aging and disease	17
Cofilin is a key regulator of oxidative stress-induced intercellular tunneling nanotubes formation	17
27P silk bioactive peptides mediate multifaceted regulation of collagen and support balance in fibroblast subpopulations	16
Microtubules and cardiovascular diseases: insights into pathology and therapeutic strategies	16
The functional significance of circRNA/miRNA/mRNA interactions as a regulatory network in lung cancer biology	16
Priming human bone marrow-derived mesenchymal stromal cells with signaling modifiers boosts their functionality: Potential application in regenerative therapies	15
Purinosomes and lysosomes interact to maintain the purine pools	15
Disulfiram/copper induces BAK-mediated caspase-independent apoptosis in MCF-7 cells	15
Corrigendum to “ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a Rac1- driven ROS production” [Int. J. Biochem. Mol. Bio. 164 (2023) 106474–106484]	15
Regulatory role of AMPK/Nrf2 signaling pathway in sevoflurane-enhanced intestinal protection against ischemia-reperfusion injury	15
The role of autophagy in intervertebral disc degeneration and the regulation mechanism of AP-2α on autophagy	15
2.5D Traction Force Microscopy: Imaging three-dimensional cell forces at interfaces and biological applications	15
Therapeutic potential of TIM-3 inhibition in cancer, viral infections, and autoimmune disorders	15
Mitochondrial homeostasis and their impact on gastric carcinoma	14
Modulatory effects of exogenous estradiol during endotoxemia	14
Single-cell transcriptomic analysis unveils dysregulated macrophage-podocyte crosstalk in membranous nephropathy	14
Chromobox protein homolog 7 (CBX7) deficiency inhibits osteoblast ferroptosis by activating the Nrf2 function in type 2 diabetic osteoporosis	14
The divergent roles of exosomes in kidney diseases: Pathogenesis, diagnostics, prognostics and therapeutics	14
Overexpression of PBX1 attenuates oxidative stress and apoptosis in diabetic cardiomyopathy by transcriptionally inhibiting TXNIP	13
A platinum(II) complex HY1-Pt overcomes cisplatin-induced resistance and attenuates metastasis of epithelial ovarian cancer by cancer cell stemness inhibition	13
UHRF1 poly-auto-ubiquitination induced by the anti-cancer drug, thymoquinone, is involved in the DNA repair machinery recruitment.	13
Adipose improves muscular atrophy caused by Sirtuin1 deficiency by promoting mitochondria synthesis	13
The mechanism underlying the TC-G 1008 rescue of reactive oxygen species (ROS)-induced osteoblast apoptosis by the upregulation of peroxiredoxin 1	13
Editorial Board	12
The role of nicotinic acetylcholine receptors in the pathophysiology and pharmacotherapy of autism spectrum disorder: Focus on α7 nicotinic receptors	12
Editorial Board	12
Editorial Board	12
Immunosenescence and macrophages: From basics to therapeutics	12
Common dysmorphic oocytes and embryos in assisted reproductive technology laboratory in association with gene alternations	12
Editorial Board	12
Editorial Board	12
Epigenetic regulation of hepatocellular carcinoma progression: MicroRNAs as therapeutic, diagnostic and prognostic factors	11
SPDYE3 promotes cell cycle and LUSC progression by regulating the CDC25C/CDK1 pathway	11
Association of long non-coding RNA in lipid metabolism: Implications in leukemia	11
YAP upregulates AMPKα1 to induce cancer cell senescence	11
RNA-based logic for selective protein expression in senescent cells	11
METTL5-mediated m6A modification of SLC7A11 promotes cervical cancer by inhibiting ferroptosis	11
Naringenin nanoparticles targeting cyclin B1 suppress the progression of rheumatoid arthritis-associated lung cancer by inhibiting fibroblast-to-myofibroblast transition	11
PLA inhibits TNF-α-induced PANoptosis of prostate cancer cells through metabolic reprogramming	11
ITCH inhibits alkaliptosis in human pancreatic cancer cells through YAP1-dependent SLC16A1 activation	10
ALDOC regulated the biological function and immune infiltration of gastric cancer cells	10
Tamoxifen upregulates the peroxisomal β-oxidation enzyme Enoyl CoA hydratase and 3-hydroxyacyl CoA hydratase ameliorating hepatic lipid accumulation in mice	10
Corrigendum to “Sodium butyrate down-regulation of indoleamine 2, 3-dioxygenase at the transcriptional and post-transcriptional levels” [Int. J. Biochem. Cell Biol. 42 (2010) 1840–1846]	10
Talin mechanotransduction in disease	10
Role of hypoxia on microRNA-dependant regulation of HGFA – HGF – c-Met signalling pathway in human progenitor and mature endothelial cells	10
Editorial Board	10

Free radicals: Relationship to Human Diseases and Potential Therapeutic applications	10
Abemaciclib-induced epithelial-mesenchymal transition mediated by cyclin-dependent kinase 4/6 independent of cell cycle arrest pathway	9
PIAS1 S510G variant acts as a genetic modifier of spinocerebellar ataxia type 3 by selectively impairing mutant ataxin-3 proteostasis	9
Mutations in the SLC35C1 gene, contributing to significant differences in fucosylation patterns, may underlie the diverse phenotypic manifestations observed in leukocyte adhesion deficiency type II pa	9
Epibrassinolide impaired colon tumor progression and induced autophagy in SCID mouse xenograft model via acting on cell cycle progression without affecting endoplasmic reticulum stress observed in vit	9
Elaiophylin exerts antitumor effects in human breast cancer cells by inducing apoptosis and modulating MAPK signaling: Therapeutic implications	9
Melatonin alleviates endoplasmic reticulum stress and its mediated inflammation in adipocytes via the PER1/ATF6 signal	9
Pathological implications of cellular stress in cardiovascular diseases	9
Syndecan-2 positively regulates Wnt/β-catenin signaling in breast cancer cells	9
Autophagy-mediated regulation of hepatic differentiation of human adipose tissue-derived mesenchymal stem cells	9
Type I and III interferons in asthma and respiratory infections: New insights for potential treatments	9
An intact zinc finger motif of the C1B domain is critical for stability and activity of diacylglycerol kinase-ε	9
Corrigendum to “Diazepam enhances melanogenesis, melanocyte dendricity and melanosome transport via the PBR/cAMP/PKA pathway” [Int. J. Biochem. Cell Biol. 116 (2019) 105620]	9
Mn2+ enhances phagocytosis of macrophages against Staphylococcus aureus by regulating autophagy	9
PARP1 controls the transcription of CD24 by ADP-ribosylating the RNA helicase DDX5 in pancreatic cancer	9
MLN4924 Suppresses head and neck squamous cell carcinoma progression by inactivating the mTOR signaling pathway via the NEDD8/CUL4/TSC2 axis	9
The potential regulation of the miR-17–92a cluster by miR-21	8
Ligustilide alleviates sepsis-associated acute kidney injury by activating Nrf2/HO-1 and PI3K/Akt signaling pathways	8
Estradiol facilitates urate excretion by reducing GLUT9 expression via ERβ/TMEM106B/PI3K/AKT1 pathway in renal tubular epithelial cells	8
Editorial Board	8
LARP4A and LARP4B in cancer: The new kids on the block	8
5'tiRNA-33-CysACA-1 promotes septic cardiomyopathy by targeting PGC-1α-mediated mitochondrial biogenesis	8
Tumor-derived microparticles promoted M2-like macrophages polarization to stimulate osteosarcoma progression	8
Modulation of bovine muscle satellite cells myogenesis by paracrine fibroblast-derived signaling in three-dimensional spinner flask culture system	8
Editorial Board	8
Corrigendum to “ABAT targeted by miR-183-5p regulates cell functions in liver cancer” [Int. J. Biochem. Cell Biol. 141 (2021) 106116]	8
Characterizing the role of extracellular domain in GLP-1R biased agonism	8
Editorial Board	8
AKT2 deficiency alleviates doxorubicin-induced cardiac injury via alleviating oxidative stress in cardiomyocytes	8
Development of a deep learning-based model to diagnose mixed-type gastric cancer accurately	8
Inhibition of M2 macrophage-mediated mesenchymal stem cell migration: Boldine attenuates elbow heterotopic ossification	8
Editorial Board	7
Enhancement of wound healing in diabetic mice by topical use of a peptide-ionic liquid conjugate	7
E2F1-mediated ectopic expression of PP1A promotes breast cancer progression via activation of YAP1	7
TRPM8 affects relative “cooling and heating” of subcellular organelles in microglia in a context-dependent manner	7
Hedgehog signalling in CD4+ T helper cell polarisation	7
Regulatory role of TEX10 gene in proliferation differentiation and apoptosis of bovine myoblasts	7
Research and application of direct current in medicine: From cellular and molecular mechanisms to clinical application in ophthalmology	7
Xiaoyou decoction suppresses cervical precancerous lesions through the activation of cellular autophagy and the upregulation of p53 expression	7
Classical psychedelics’ action on brain monoaminergic systems	7
Single-cell transcriptomics and metabolomics reveal the potential role of ASRGL1 in metabolic reprogramming and invasion of nasopharyngeal carcinoma cells	7
Influence of the ERK/CHGB pathway in breast cancer progression under chronic stress	7
Identify key genes and biological processes participated in obesity-related cancer based on studying 12 cancers	7
IL-22 relieves hepatic ischemia-reperfusion injury by inhibiting mitochondrial apoptosis based on the activation of STAT3	7
Roles of lipid metabolism and its regulatory mechanism in idiopathic pulmonary fibrosis: A review	7
Editorial Board	7
Visualizing, quantifying and mapping chromatin remodelers at work with single-molecule and single-cell imaging	7
Function of connexin 43 and RhoA/LIMK2/Cofilin signaling pathway in transient changes of contraction and dilation of human umbilical arterial smooth muscle cells	7
Serum-assisted metabolic priming enables robust structural maturation of hiPSC-cardiomyocytes in 2D and 3D systems	7
To what extent may aminochrome increase the vulnerability of dopaminergic neurons in the context of Parkinson's disease	7
Melatonin protects Leydig cells from HT-2 toxin-induced ferroptosis and apoptosis via glucose-6-phosphate dehydrogenase/glutathione -dependent pathway	7
The use of serotonin type 7 receptor antagonists as a pharmacological intervention in chronic stress. Insights from animal studies	7
Single-cell sequencing reveals the antifibrotic effects of YAP/TAZ in systemic sclerosis	7
CircTHBS1 aggravates peritoneal fibrosis by sponging miR-18a-5p and interacting with CTGF	7
The E3 ubiquitin ligase SCF (FBXW10)-mediated LATS2 degradation regulates angiogenesis and liver metastasis in colorectal cancer	7
Adipose tissue macrophages-derived exosomal MiR-500a-5p under high glucose promotes adipocytes inflammation by suppressing Nrf2 expression	7