Medical Oncology

Article	Citations
Steps in metastasis: an updated review	130
Activation of the HGF/c-MET axis promotes lenvatinib resistance in hepatocellular carcinoma cells with high c-MET expression	66
Cancer treatment during COVID-19 pandemic	52
Delta-radiomics increases multicentre reproducibility: a phantom study	47
Exosomes and cancer: from molecular mechanisms to clinical applications	47
Combating TKI resistance in CML by inhibiting the PI3K/Akt/mTOR pathway in combination with TKIs: a review	32
Will traditional biopsy be substituted by radiomics and liquid biopsy for breast cancer diagnosis and characterisation?	31
An updated review of epidemiology, risk factors, and management of male breast cancer	31
Strategies for having a more effective and less toxic CAR T-cell therapy for acute lymphoblastic leukemia	30
Myths and facts about artificial intelligence: why machine- and deep-learning will not replace interventional radiologists	29
Artificial Intelligence in radiotherapy: state of the art and future directions	29
Cancer and COVID-19: Why are cancer patients more susceptible to COVID-19?	28
COVID-19 and cancer care: what do international guidelines say?	24
Neuroendocrine breast carcinoma: a rare but challenging entity	24
Targeting of oncogenic signaling pathways by berberine for treatment of colorectal cancer	23
Circular RNAs and their participation in stemness of cancer	23
MicroRNAs and target molecules in bladder cancer	23
The anti-angiogenic agent lenvatinib induces tumor vessel normalization and enhances radiosensitivity in hepatocellular tumors	23
Extracellular vesicle isolation from human renal cancer tissue	22
Associated analysis of PER1/TUBB2B with endometrial cancer development caused by circadian rhythm disorders	19
Cancer stem cells in colorectal cancer and the association with chemotherapy resistance	19
Bexarotene inhibits cell proliferation by inducing oxidative stress, DNA damage and apoptosis via PPARγ/ NF-κB signaling pathway in C6 glioma cells	19
Luteolin and cancer metastasis suppression: focus on the role of epithelial to mesenchymal transition	19
Comparative bioinformatical analysis of pancreatic head cancer and pancreatic body/tail cancer	19
RFA of primary and metastatic lung tumors: long-term results	18

Identification of hub genes associated with obesity-induced hepatocellular carcinoma risk based on integrated bioinformatics analysis	18
Wee1 kinase inhibitor AZD1775 potentiates CD8+ T cell-dependent antitumour activity via dendritic cell activation following a single high dose of irradiation	18
Acute myeloid leukemia sensitivity to metabolic inhibitors: glycolysis showed to be a better therapeutic target	18
Cinnamaldehyde induces endogenous apoptosis of the prostate cancer-associated fibroblasts via interfering the Glutathione-associated mitochondria function	17
De novo neuroendocrine transdifferentiation in primary prostate cancer–a phenotype associated with advanced clinico-pathologic features and aggressive outcome	17
Identification of novel biomarkers, MUC5AC, MUC1, KRT7, GAPDH, CD44 for gastric cancer	17
Vaccination of cancer patients against COVID-19: towards the end of a dilemma	16
Integration of gene expression data identifies key genes and pathways in colorectal cancer	16
Molecular targets and therapeutics in chemoresistance of triple-negative breast cancer	15
Melittin, a honeybee venom derived peptide for the treatment of chemotherapy-induced peripheral neuropathy	15
PARP1-modulated chromatin remodeling is a new target for cancer treatment	15
The role of inflammatory indices in the outcome of COVID-19 cancer patients	14
Cancer induced bone pain: current management and future perspectives	14
Estimating copy number using next-generation sequencing to determine ERBB2 amplification status	14
PSMA: a game changer in the diagnosis and treatment of advanced prostate cancer	14
Treating MCF7 breast cancer cell with proteasome inhibitor Bortezomib restores apoptotic factors and sensitizes cell to Docetaxel	14
Combination of resveratrol and BIBR1532 inhibits proliferation of colon cancer cells by repressing expression of LncRNAs	14
Knockdown of lncRNA HIF1A-AS2 increases drug sensitivity of SCLC cells in association with autophagy	13
Cancer stem cell characteristics and their potential as therapeutic targets	13
High KIFC1 expression is associated with poor prognosis in prostate cancer	13
Organoid culture system for patient-derived lung metastatic osteosarcoma	13
Suppression of PTTG1 inhibits cell angiogenesis, migration and invasion in glioma cells	13
Quality of life, symptoms and dietary habits in oncology outpatients with malnutrition: A cross-sectional study	12
Resveratrol effects in oral cancer cells: a comprehensive review	12
Multidisciplinary total eradication therapy (TET) in men with newly diagnosed oligometastatic prostate cancer	12
SBRT in non-spine bone metastases: a literature review	12
Apigenin increases radiosensitivity of glioma stem cells by attenuating HIF-1α-mediated glycolysis	12
Melittin inhibits the expression of key genes involved in tumor microenvironment formation by suppressing HIF-1α signaling in breast cancer cells	12
Bioymifi, a novel mimetic of TNF-related apoptosis-induced ligand (TRAIL), stimulates eryptosis	12
Impact of preexisting antinuclear antibodies on combined immunotherapy and chemotherapy in advanced non-small cell lung cancer patients	12
Docetaxel plus cisplatin in recurrent and/or metastatic non-squamous-cell head and neck cancer: a multicenter phase II trial	12
Innovation in cancer therapeutics and regulatory perspectives	12
CDK9 inhibitors in multiple myeloma: a review of progress and perspectives	12
MRI-guided vacuum-assisted breast biopsy: experience of a single tertiary referral cancer centre and prospects for the future	11
Lipid droplet evolution gives insight into polyaneuploid cancer cell lipid droplet functions	11
Synergistic effects of multiple myeloma cells and tumor-associated macrophages on vascular endothelial cells in vitro	11
Head and neck radiotherapy amid the COVID-19 pandemic: practice recommendations of the Italian Association of Radiotherapy and Clinical Oncology (AIRO)	11
N-Myc promotes angiogenesis and therapeutic resistance of prostate cancer by TEM8	11
COVID-19 pandemic: a new cause of unplanned interruption of radiotherapy in breast cancer patients	11
ABLATE: a score to predict complications and recurrence rate in percutaneous treatments of renal lesions	11
Effects of SLC31A1 and ATP7B polymorphisms on platinum resistance in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiotherapy	11
Iron overload is related to muscle wasting in patients with cachexia of gastric cancer: using quantitative proteome analysis	11
Influence of ballroom dancing on fatigue, body image, self-efficacy, and endurance of cancer patients and their partners	11
The CXCL12/CXCR7 signalling axis promotes proliferation and metastasis in cervical cancer	11
Live cell molecular analysis of primary prostate cancer organoids identifies persistent androgen receptor signaling	11
Effectiveness and safety in radiofrequency ablation of pulmonary metastases from HCC: a five years study	10
Regulatory mechanisms of heme regulatory protein BACH1: a potential therapeutic target for cancer	10
Clinical characteristics of adrenal insufficiency as an immune-related adverse event in non-small-cell lung cancer	10
Isolation and characterization of a novel GRP78-specific single-chain variable fragment (scFv) using ribosome display method	10
Preliminary results in unresectable cholangiocarcinoma treated by CT percutaneous irreversible electroporation: feasibility, safety and efficacy	10

Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma	10
MYH9 suppresses melanoma tumorigenesis, metastasis and regulates tumor microenvironment	10
Combined crizotinib and endocrine drugs inhibit proliferation, migration, and colony formation of breast cancer cells via downregulation of MET and estrogen receptor	10
Short-term effects of a Paleolithic lifestyle intervention in breast cancer patients undergoing radiotherapy: a pilot and feasibility study	10
A phase I/II study of docetaxel in combination with pegylated liposomal doxorubicin in metastatic castration-resistant prostate cancer	9
Transcription factor YY1 mediates epithelial–mesenchymal transition through the TGFβ signaling pathway in bladder cancer	9
The prostate-specific membrane antigen (PSMA)-targeted radiotracer 18F-DCFPyL detects tumor neovasculature in metastatic, advanced, radioiodine-refractory, differentiated thyroid cancer	9
Upregulation of apoptotic protease activating factor-1 expression correlates with anti-tumor effect of taxane drug	9
The effect of metformin when combined with neoadjuvant chemotherapy in breast cancer patients	9
Prevalence of mutations in BRCA and MMR genes in patients affected with hereditary endometrial cancer	9
nab-Paclitaxel and cisplatin followed by cisplatin and radiation (Arm 1) and nab-paclitaxel followed by cetuximab and radiation (Arm 2) for locally advanced head and neck squamous-cell carcinoma: a mu	9
Laparoscopic thermoablation for hepatocellular carcinoma in patients with liver cirrhosis: an effective procedure for tricky tumors	9
The effect of itraconazole on the clinical outcomes of patients with advanced non-small cell lung cancer receiving platinum-based chemotherapy: a randomized controlled study	9
ceRNA network development and tumor-infiltrating immune cell analysis in hepatocellular carcinoma	9
Trillin prevents proliferation and induces apoptosis through inhibiting STAT3 nuclear translocation in hepatoma carcinoma cells	9
Employing bioinformatics analysis to identify hub genes and microRNAs involved in colorectal cancer	9
Suppressed PLIN3 frequently occurs in prostate cancer, promoting docetaxel resistance via intensified autophagy, an event reversed by chloroquine	9
NUC-1031, use of ProTide technology to circumvent gemcitabine resistance: current status in clinical trials	9
A closer look to the new frontier of artificial intelligence in the percutaneous treatment of primary lesions of the liver	9
SARS-CoV-2 spike protein inhibits growth of prostate cancer: a potential role of the COVID-19 vaccine killing two birds with one stone	8
The apoptotic efficacy of succinic acid on renal cancer cell lines	8
Possible protective effect of pantoprazole against cisplatin-induced nephrotoxicity in head and neck cancer patients: a randomized controlled trial	8
Carboxyl-terminal polypeptide fragment of MUC16 combing stathmin1 promotes gallbladder cancer cell migration and invasion	8
SNRPB is a mediator for cellular response to cisplatin in non-small-cell lung cancer	8
Adoptive cell therapy of patient-derived renal cell carcinoma xenograft model with IL-15-induced γδT cells	8
Combination therapy with miR-34a and doxorubicin synergistically induced apoptosis in T-cell acute lymphoblastic leukemia cell line	8
The effective natural compounds for inhibiting Cervical cancer	8
The texture analysis as a predictive method in the assessment of the cytological specimen of CT-guided FNAC of the lung cancer	8
The function of Cav-1 in MDA-MB-231 breast cancer cell migration and invasion induced by ectopic ATP5B	8
Balstilimab and other immunotherapy for recurrent and metastatic cervical cancer	8
Critical pathways of oral squamous cell carcinoma: molecular biomarker and therapeutic intervention	8
Novel molecules as the emerging trends in cancer treatment: an update	8
Thermal Ablation versus SBRT in liver tumours: pros and cons	8
Identification of candidate biomarkers and therapeutic drugs of colorectal cancer by integrated bioinformatics analysis	8
Forward to a methodological proposal to support cancer patients: the dialogics’ contribution for the precision care	8
Treating metastatic clear-cell renal cell carcinoma: beyond immunotherapy	7
ErbB2 promotes breast cancer metastatic potential via HSF1/LDHA axis-mediated glycolysis	7
Can artificial intelligence overtake human intelligence on the bumpy road towards glioma therapy?	7
SOX2 knockdown with siRNA reverses cisplatin resistance in NSCLC by regulating APE1 signaling	7
The clinical significance of CD49e and CD56 for multiple myeloma in the novel agents era	7
Effects of electroporation on anticancer activity of 5-FU and newly synthesized zinc(II) complex in chemotherapy-resistance human brain tumor cells	7
The DPP-IV inhibitor saxagliptin promotes the migration and invasion of papillary thyroid carcinoma cells via the NRF2/HO1 pathway	7
Potential use of kiwifruit extract for treatment of melanoma	7
Primary pulmonary lymphoepithelioma-like carcinoma	7
Submicron particle docetaxel intratumoral injection in combination with anti-mCTLA-4 into 4T1-Luc orthotopic implants reduces primary tumor and metastatic pulmonary lesions	7
Disease spectrum of gastric cancer susceptibility genes	7
Identification of the dominant angiogenic CXCL class chemokines associated with non-small cell lung cancer via bioinformatics tools	7
Identification of pancreatic cancer type related factors by Weighted Gene Co-Expression Network Analysis	7
Mefenamic acid as a promising therapeutic medicine against colon cancer in tumor-bearing mice	7
Exosome application in tumorigenesis: diagnosis and treatment of melanoma	7
ERVs-TLR3-IRF axis is linked to myelodysplastic syndrome pathogenesis	7
Resveratrol triggers anti-proliferative and apoptotic effects in FLT3-ITD-positive acute myeloid leukemia cells via inhibiting ceramide catabolism enzymes	6
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy	6
DNMT1 and miRNAs: possible epigenetics footprints in electromagnetic fields utilization in oncology	6
Preliminary evaluation on the beneficial effects of pioglitazone in the treatment of endometrial cancer	6
The effects of chemotherapeutic drugs on PD-L1 gene expression in breast cancer cell lines	6
The genomic architecture of metastasis in breast cancer: focus on mechanistic aspects, signalling pathways and therapeutic strategies	6
Percutaneous US-guided MWA of small liver HCC: predictors of outcome and risk factors for complications from a single center experience	6
CDK2-instigates C/EBPα degradation through SKP2 in Acute myeloid leukemia	6
Identification BCL6 and miR-30 family associating with Ibrutinib resistance in activated B-cell-like diffuse large B-cell lymphoma	6
Ablation, consolidation and radiotherapy for the management of metastatic lesions of the spine: impact on the quality of life in a mid-term clinical and diagnostic follow-up in a pilot study	6
The inhibition of Panc1 cancer cells invasion by hAMSCs secretome through suppression of tyrosine phosphorylation of SGK223 (at Y411 site), c-Src (at Y416, Y530 sites), AKT activity, and JAK1/Stat3 si	6
Glioblastoma recurrent cells switch between ATM and ATR pathway as an alternative strategy to survive radiation stress	6
Bioinformatic analysis of dysregulated proteins in prostate cancer patients reveals putative urinary biomarkers and key biological pathways	6
Identification of potential genes associated with ALDH1A1 overexpression and cyclophosphamide resistance in chronic myelogenous leukemia using network analysis	6
Phase II prospective trial “Give Me Five” short-term high precision radiotherapy for early prostate cancer with simultaneous boost to the dominant intraprostatic lesion: the impact of toxicity on qual	6
Knockout of high-mobility group box 1 in B16F10 melanoma cells induced host immunity-mediated suppression of in vivo tumor growth	6
Restraint stress abates the antioxidant potential of melatonin on dimethyl benz (a) anthracene (DMBA) induced carcinogenesis	6
Analyzing the impact of ATF3 in tumorigenesis and immune cell infiltration of ovarian tumor: a bioinformatics study	6
Ablation for hepatocellular carcinoma: beyond the standard indications	6
Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchymal phenotype	6
HR-HPV viral load quality detection provide more accurate prediction for residual lesions after treatment: a prospective cohort study in patients with high-grade squamous lesions or worse	6
Identification of key genes in the tumor microenvironment of lung adenocarcinoma	6
Economic perspective of cancer treatment in India	6
RNA-binding protein Musashi2 regulates Hippo signaling via SAV1 and MOB1 in pancreatic cancer	5
What is the damage? Testicular germ cell tumour survivors deficient in testosterone at risk of metabolic syndrome and a need for medical intervention	5
Effects of metformin on human bone-derived mesenchymal stromal cell—breast cancer cell line interactions	5
ELK1-induced up-regulation of KIF26B promotes cell cycle progression in breast cancer	5
The “collateral damage” of the war on COVID-19: impact of the pandemic on the care of epithelial ovarian cancer	5
Combination of dasatinib and okadaic acid induces apoptosis and cell cycle arrest by targeting protein phosphatase PP2A in chronic myeloid leukemia cells	5

Back to (new) normality—A CODRAL/AIRO-L survey on cancer radiotherapy in Lombardy during Italian COVID-19 phase 2	5
Nicaraven prevents the fast growth of inflamed tumors by an anti-inflammatory mechanism	5
Providing optimal interventional oncology procedures at one of the COVID-19 referral center in Italy	5
Sarcoid-like reaction in cases treated by checkpoint inhibitors	5
Upfront metastasis-directed therapy in oligorecurrent prostate cancer does not decrease the time from initiation of androgen deprivation therapy to castration resistance	5
β-Arrestin inhibition induces autophagy, apoptosis, G0/G1 cell cycle arrest in agonist-activated V2R receptor in breast cancer cells	5
B7-1 and GM-CSF enhance the anti-tumor immune effect of DC-tumor fusion vaccine in the treatment of prostate cancer	5
Follow-up of percutaneous microwave (MW) ablation of hepatic lesion: predictive value of CT at 24-h compared with CT at 1 month	5
HELZ2 promotes K63-linked polyubiquitination of c-Myc to induce retinoblastoma tumorigenesis	5
Biological activity and molecular docking studies of some new quinolines as potent anticancer agents	5
Identification of biomarkers associated with extracellular vesicles based on an integrative pan-cancer bioinformatics analysis	5
c-Met/MAPK pathway promotes the malignant progression of residual hepatocellular carcinoma cells after insufficient radiofrequency ablation	5
Silencing Akt1 enhances the resistance of prostate cancer cells to starvation and inhibits starvation-induced lung metastasis through epithelial–mesenchymal transition in prostate cancer	5
The inhibition effect of natural food supplement active ingredients on TP63 carcinoma cell	5
Immunohistochemical evaluation of microsatellite instability in resected colorectal liver metastases: a preliminary experience	5
Immune microenvironment-related gene mapping predicts immunochemotherapy response and prognosis in diffuse large B-cell lymphoma	5
Diosmetin induces apoptosis in ovarian cancer cells by activating reactive oxygen species and inhibiting the Nrf2 pathway	5
DNA methylation marker to estimate ovarian cancer cell fraction	5
Identification of cell cycle as the critical pathway modulated by exosome-derived microRNAs in gallbladder carcinoma	5
RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression	5
AFP peptide (AFPep) as a potential growth factor for prostate cancer	5
Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer	5
Defining candidate mRNA and protein EV biomarkers to discriminate ccRCC and pRCC from non-malignant renal cells in vitro	5
Percutaneous microwave ablation therapy of renal cancer local relapse after radical nephrectomy: a feasibility and efficacy study	5
Prospective evaluation of 68Ga-PSMA-11 PET/CT in Chinese men with biochemical recurrence after radical prostatectomy for prostate cancer: relationships between location of recurrence, time after prost	5
The investigation of the healing effect of active ingredients in traditional medicinal plants on lung cancer	5