OOIR: Observatory of International Research

Papers

(The median citation count of Medical Oncology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Steps in metastasis: an updated review	160
Exosomes and cancer: from molecular mechanisms to clinical applications	51
An updated review of epidemiology, risk factors, and management of male breast cancer	40
Combating TKI resistance in CML by inhibiting the PI3K/Akt/mTOR pathway in combination with TKIs: a review	35
The anti-angiogenic agent lenvatinib induces tumor vessel normalization and enhances radiosensitivity in hepatocellular tumors	32
Strategies for having a more effective and less toxic CAR T-cell therapy for acute lymphoblastic leukemia	30
Cancer and COVID-19: Why are cancer patients more susceptible to COVID-19?	29
MicroRNAs and target molecules in bladder cancer	26
Luteolin and cancer metastasis suppression: focus on the role of epithelial to mesenchymal transition	25
Cancer stem cells in colorectal cancer and the association with chemotherapy resistance	24
Innovation in cancer therapeutics and regulatory perspectives	24
Bexarotene inhibits cell proliferation by inducing oxidative stress, DNA damage and apoptosis via PPARγ/ NF-κB signaling pathway in C6 glioma cells	21
PARP1-modulated chromatin remodeling is a new target for cancer treatment	21
Cancer induced bone pain: current management and future perspectives	21
Identification of hub genes associated with obesity-induced hepatocellular carcinoma risk based on integrated bioinformatics analysis	21
CDK9 inhibitors in multiple myeloma: a review of progress and perspectives	20
Organoid culture system for patient-derived lung metastatic osteosarcoma	19
Molecular targets and therapeutics in chemoresistance of triple-negative breast cancer	19
De novo neuroendocrine transdifferentiation in primary prostate cancer–a phenotype associated with advanced clinico-pathologic features and aggressive outcome	19
Vaccination of cancer patients against COVID-19: towards the end of a dilemma	19
Cancer stem cell characteristics and their potential as therapeutic targets	18
The role of inflammatory indices in the outcome of COVID-19 cancer patients	18
Apigenin increases radiosensitivity of glioma stem cells by attenuating HIF-1α-mediated glycolysis	17
PSMA: a game changer in the diagnosis and treatment of advanced prostate cancer	17
Resveratrol effects in oral cancer cells: a comprehensive review	16

Melittin, a honeybee venom derived peptide for the treatment of chemotherapy-induced peripheral neuropathy	16
Quality of life, symptoms and dietary habits in oncology outpatients with malnutrition: A cross-sectional study	16
SBRT in non-spine bone metastases: a literature review	16
Knockdown of lncRNA HIF1A-AS2 increases drug sensitivity of SCLC cells in association with autophagy	16
Integration of gene expression data identifies key genes and pathways in colorectal cancer	16
Estimating copy number using next-generation sequencing to determine ERBB2 amplification status	15
Treating MCF7 breast cancer cell with proteasome inhibitor Bortezomib restores apoptotic factors and sensitizes cell to Docetaxel	15
Combination of resveratrol and BIBR1532 inhibits proliferation of colon cancer cells by repressing expression of LncRNAs	15
N-Myc promotes angiogenesis and therapeutic resistance of prostate cancer by TEM8	14
High KIFC1 expression is associated with poor prognosis in prostate cancer	14
The CXCL12/CXCR7 signalling axis promotes proliferation and metastasis in cervical cancer	14
Melittin inhibits the expression of key genes involved in tumor microenvironment formation by suppressing HIF-1α signaling in breast cancer cells	13
Iron overload is related to muscle wasting in patients with cachexia of gastric cancer: using quantitative proteome analysis	13
Live cell molecular analysis of primary prostate cancer organoids identifies persistent androgen receptor signaling	13
The prostate-specific membrane antigen (PSMA)-targeted radiotracer 18F-DCFPyL detects tumor neovasculature in metastatic, advanced, radioiodine-refractory, differentiated thyroid cancer	13
Docetaxel plus cisplatin in recurrent and/or metastatic non-squamous-cell head and neck cancer: a multicenter phase II trial	13
Isolation and characterization of a novel GRP78-specific single-chain variable fragment (scFv) using ribosome display method	13
Impact of preexisting antinuclear antibodies on combined immunotherapy and chemotherapy in advanced non-small cell lung cancer patients	13
Possible protective effect of pantoprazole against cisplatin-induced nephrotoxicity in head and neck cancer patients: a randomized controlled trial	12
Lipid droplet evolution gives insight into polyaneuploid cancer cell lipid droplet functions	12
nab-Paclitaxel and cisplatin followed by cisplatin and radiation (Arm 1) and nab-paclitaxel followed by cetuximab and radiation (Arm 2) for locally advanced head and neck squamous-cell carcinoma: a mu	12
Bioymifi, a novel mimetic of TNF-related apoptosis-induced ligand (TRAIL), stimulates eryptosis	12
Synergistic effects of multiple myeloma cells and tumor-associated macrophages on vascular endothelial cells in vitro	12
Influence of ballroom dancing on fatigue, body image, self-efficacy, and endurance of cancer patients and their partners	12
Combined crizotinib and endocrine drugs inhibit proliferation, migration, and colony formation of breast cancer cells via downregulation of MET and estrogen receptor	12
Prevalence of mutations in BRCA and MMR genes in patients affected with hereditary endometrial cancer	12
Short-term effects of a Paleolithic lifestyle intervention in breast cancer patients undergoing radiotherapy: a pilot and feasibility study	12
Effects of SLC31A1 and ATP7B polymorphisms on platinum resistance in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiotherapy	11
COVID-19 pandemic: a new cause of unplanned interruption of radiotherapy in breast cancer patients	11
Suppressed PLIN3 frequently occurs in prostate cancer, promoting docetaxel resistance via intensified autophagy, an event reversed by chloroquine	11
The apoptotic efficacy of succinic acid on renal cancer cell lines	11
The effect of metformin when combined with neoadjuvant chemotherapy in breast cancer patients	11
Identification of the dominant angiogenic CXCL class chemokines associated with non-small cell lung cancer via bioinformatics tools	11
Regulatory mechanisms of heme regulatory protein BACH1: a potential therapeutic target for cancer	11
Balstilimab and other immunotherapy for recurrent and metastatic cervical cancer	11
Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma	11
Combination therapy with miR-34a and doxorubicin synergistically induced apoptosis in T-cell acute lymphoblastic leukemia cell line	10
Identification BCL6 and miR-30 family associating with Ibrutinib resistance in activated B-cell-like diffuse large B-cell lymphoma	10
Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchymal phenotype	10
Employing bioinformatics analysis to identify hub genes and microRNAs involved in colorectal cancer	10
Critical pathways of oral squamous cell carcinoma: molecular biomarker and therapeutic intervention	10
ceRNA network development and tumor-infiltrating immune cell analysis in hepatocellular carcinoma	10
The inhibition of Panc1 cancer cells invasion by hAMSCs secretome through suppression of tyrosine phosphorylation of SGK223 (at Y411 site), c-Src (at Y416, Y530 sites), AKT activity, and JAK1/Stat3 si	10
The effect of itraconazole on the clinical outcomes of patients with advanced non-small cell lung cancer receiving platinum-based chemotherapy: a randomized controlled study	10
Upregulation of apoptotic protease activating factor-1 expression correlates with anti-tumor effect of taxane drug	10
Novel molecules as the emerging trends in cancer treatment: an update	10
Identification of candidate biomarkers and therapeutic drugs of colorectal cancer by integrated bioinformatics analysis	10
H2O2 enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage	9
Defining candidate mRNA and protein EV biomarkers to discriminate ccRCC and pRCC from non-malignant renal cells in vitro	9
Forward to a methodological proposal to support cancer patients: the dialogics’ contribution for the precision care	9

CDK2-instigates C/EBPα degradation through SKP2 in Acute myeloid leukemia	9
Mefenamic acid as a promising therapeutic medicine against colon cancer in tumor-bearing mice	9
The effects of chemotherapeutic drugs on PD-L1 gene expression in breast cancer cell lines	9
Effects of electroporation on anticancer activity of 5-FU and newly synthesized zinc(II) complex in chemotherapy-resistance human brain tumor cells	9
SARS-CoV-2 spike protein inhibits growth of prostate cancer: a potential role of the COVID-19 vaccine killing two birds with one stone	9
SNRPB is a mediator for cellular response to cisplatin in non-small-cell lung cancer	9
The function of Cav-1 in MDA-MB-231 breast cancer cell migration and invasion induced by ectopic ATP5B	9
Sarcoid-like reaction in cases treated by checkpoint inhibitors	8
A 12-chemokine gene signature is associated with the enhanced immunogram scores and is relevant for precision immunotherapy	8
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy	8
DNMT1 and miRNAs: possible epigenetics footprints in electromagnetic fields utilization in oncology	8
SOX2 knockdown with siRNA reverses cisplatin resistance in NSCLC by regulating APE1 signaling	8
Adoptive cell therapy of patient-derived renal cell carcinoma xenograft model with IL-15-induced γδT cells	8
The DPP-IV inhibitor saxagliptin promotes the migration and invasion of papillary thyroid carcinoma cells via the NRF2/HO1 pathway	8
Potential use of kiwifruit extract for treatment of melanoma	8
Carboxyl-terminal polypeptide fragment of MUC16 combing stathmin1 promotes gallbladder cancer cell migration and invasion	8
Submicron particle docetaxel intratumoral injection in combination with anti-mCTLA-4 into 4T1-Luc orthotopic implants reduces primary tumor and metastatic pulmonary lesions	8
Disease spectrum of gastric cancer susceptibility genes	8
Biological activity and molecular docking studies of some new quinolines as potent anticancer agents	8
ErbB2 promotes breast cancer metastatic potential via HSF1/LDHA axis-mediated glycolysis	8
Exosome application in tumorigenesis: diagnosis and treatment of melanoma	8
ERVs-TLR3-IRF axis is linked to myelodysplastic syndrome pathogenesis	8
Resveratrol triggers anti-proliferative and apoptotic effects in FLT3-ITD-positive acute myeloid leukemia cells via inhibiting ceramide catabolism enzymes	7
AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells	7
Identification of cell cycle as the critical pathway modulated by exosome-derived microRNAs in gallbladder carcinoma	7
Identification of potential genes associated with ALDH1A1 overexpression and cyclophosphamide resistance in chronic myelogenous leukemia using network analysis	7
Targeting Hedgehog signalling in CD133-positive hepatocellular carcinoma: improving Lenvatinib therapeutic efficiency	7
Diosmetin induces apoptosis in ovarian cancer cells by activating reactive oxygen species and inhibiting the Nrf2 pathway	7
Can artificial intelligence overtake human intelligence on the bumpy road towards glioma therapy?	7
The effective natural compounds for inhibiting Cervical cancer	7
Preliminary evaluation on the beneficial effects of pioglitazone in the treatment of endometrial cancer	7
Upfront metastasis-directed therapy in oligorecurrent prostate cancer does not decrease the time from initiation of androgen deprivation therapy to castration resistance	7
Economic perspective of cancer treatment in India	7
ARA-linker-TGFαL3: a novel chimera protein to target breast cancer cells	7
DNA damage induced cellular senescence and it’s PTEN-armed exosomes—the warriors against prostate carcinoma cells	7
Knockout of high-mobility group box 1 in B16F10 melanoma cells induced host immunity-mediated suppression of in vivo tumor growth	7
The clinical significance of CD49e and CD56 for multiple myeloma in the novel agents era	7
The genomic architecture of metastasis in breast cancer: focus on mechanistic aspects, signalling pathways and therapeutic strategies	7
LPA3 is a precise therapeutic target and potential biomarker for ovarian cancer	7
The combination therapy of Everolimus and anti-PD-1 improves the antitumor effect by regulating CD8+ T cells in bladder cancer	7
Combination of dasatinib and okadaic acid induces apoptosis and cell cycle arrest by targeting protein phosphatase PP2A in chronic myeloid leukemia cells	6
The “collateral damage” of the war on COVID-19: impact of the pandemic on the care of epithelial ovarian cancer	6
RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression	6
DNA methylation marker to estimate ovarian cancer cell fraction	6
Interferon regulatory factor-1 regulates cisplatin-induced apoptosis and autophagy in A549 lung cancer cells	6
Bioinformatic analysis of dysregulated proteins in prostate cancer patients reveals putative urinary biomarkers and key biological pathways	6
ELK1-induced up-regulation of KIF26B promotes cell cycle progression in breast cancer	6
β-Arrestin inhibition induces autophagy, apoptosis, G0/G1 cell cycle arrest in agonist-activated V2R receptor in breast cancer cells	6
Glioblastoma recurrent cells switch between ATM and ATR pathway as an alternative strategy to survive radiation stress	6
B7-1 and GM-CSF enhance the anti-tumor immune effect of DC-tumor fusion vaccine in the treatment of prostate cancer	6
Molecular analysis of cell survival and death pathways in the proteasome inhibitor bortezomib-resistant PC3 prostate cancer cell line	6
The analysis of N6-methyladenosine regulators impacting the immune infiltration in clear cell renal cell carcinoma	6
Identification of key genes in the tumor microenvironment of lung adenocarcinoma	6
Identification of the critical genes and miRNAs in hepatocellular carcinoma by integrated bioinformatics analysis	6
Notch signaling in oral pre-cancer and oral cancer	6
HELZ2 promotes K63-linked polyubiquitination of c-Myc to induce retinoblastoma tumorigenesis	6
Analyzing the impact of ATF3 in tumorigenesis and immune cell infiltration of ovarian tumor: a bioinformatics study	6
Nicaraven prevents the fast growth of inflamed tumors by an anti-inflammatory mechanism	6
c-Met/MAPK pathway promotes the malignant progression of residual hepatocellular carcinoma cells after insufficient radiofrequency ablation	6