OOIR: Observatory of International Research

Papers

(The median citation count of Medical Oncology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
The genomic architecture of metastasis in breast cancer: focus on mechanistic aspects, signalling pathways and therapeutic strategies	44
Oncotype DX testing does not affect clinical practice in stage IIa colon cancer	44
The immunomodulatory effects of Candida albicans isolated from the normal gastrointestinal microbiome of the elderly on colorectal cancer	28
The combined therapy of miR-383-5p restoration and paclitaxel for treating MDA-MB-231 breast cancer	27
The role of inflammatory indices in the outcome of COVID-19 cancer patients	27
COVID-19 pandemic: a new cause of unplanned interruption of radiotherapy in breast cancer patients	24
How to ensure uninterrupted treatment of radiotherapy patients during delta variants of SARS-CoV-2 virus epidemic: the latest experience from Xi’an, China	20
Can the host immune response against SARS-CoV2 also cause an anticancer effect?	20
PSMA: a game changer in the diagnosis and treatment of advanced prostate cancer	20
Regulatory mechanisms of heme regulatory protein BACH1: a potential therapeutic target for cancer	20
Identification of the role of mono-ADP-ribosylation in colorectal cancer by integrated transcriptome analysis	19
Detection of mutations in CML patients resistant to tyrosine kinase inhibitor: imatinib mesylate therapy	18
Enhancement of Apo2L/TRAIL signaling pathway receptors by the activation of Klotho gene with CRISPR/Cas9 in Caco-2 colon cancer cells	17
Notch signaling in oral pre-cancer and oral cancer	17
The “collateral damage” of the war on COVID-19: impact of the pandemic on the care of epithelial ovarian cancer	17
DNMT1 and miRNAs: possible epigenetics footprints in electromagnetic fields utilization in oncology	16
The inhibition of Panc1 cancer cells invasion by hAMSCs secretome through suppression of tyrosine phosphorylation of SGK223 (at Y411 site), c-Src (at Y416, Y530 sites), AKT activity, and JAK1/Stat3 si	16
ARA-linker-TGFαL3: a novel chimera protein to target breast cancer cells	15
Innovation in cancer therapeutics and regulatory perspectives	15
sABLATE: a simplified ABLATE score for prediction of complications and outcome in percutaneous thermal ablation of renal lesions	14
Levofloxacin might be safe to use for OSCC patients	14
Mefenamic acid as a promising therapeutic medicine against colon cancer in tumor-bearing mice	14
Combined evaluation of proliferation and apoptosis to calculate IC50 of VPA-induced PANC-1 cells and assessing its effect on the Wnt signaling pathway	13
Impact of intravesical instillation of a novel biological response modifier (P-MAPA) on progress of non-muscle invasive bladder cancer treatment in a rat model	13
PARP1-modulated chromatin remodeling is a new target for cancer treatment	13

Computational study on novel natural inhibitors targeting BCL2	13
Systematic identification of the cancer pathways and molecules related with breast cancer immunogenicity	13
Overcoming resistance to targeted therapy using MET inhibitors in solid cancers: evidence from preclinical and clinical studies	13
A linkage between effectual genes in progression of CRC through canonical and non-canonical TGF-β signaling pathways	13
AFP peptide (AFPep) as a potential growth factor for prostate cancer	13
Defining candidate mRNA and protein EV biomarkers to discriminate ccRCC and pRCC from non-malignant renal cells in vitro	12
Direct oral anticoagulants in cancer patients: which help from the specialist hemostasis and thrombosis laboratory?	12
Submicron particle docetaxel intratumoral injection in combination with anti-mCTLA-4 into 4T1-Luc orthotopic implants reduces primary tumor and metastatic pulmonary lesions	12
In silico bioinformatics analysis for identification of differentially expressed genes and therapeutic drug molecules in Glucocorticoid-resistant Multiple myeloma	12
Interferon regulatory factor-1 regulates cisplatin-induced apoptosis and autophagy in A549 lung cancer cells	12
DNA methylation marker to estimate ovarian cancer cell fraction	12
Critical pathways of oral squamous cell carcinoma: molecular biomarker and therapeutic intervention	11
Silencing Akt1 enhances the resistance of prostate cancer cells to starvation and inhibits starvation-induced lung metastasis through epithelial–mesenchymal transition in prostate cancer	11
Resveratrol triggers anti-proliferative and apoptotic effects in FLT3-ITD-positive acute myeloid leukemia cells via inhibiting ceramide catabolism enzymes	11
Knockdown of lncRNA HIF1A-AS2 increases drug sensitivity of SCLC cells in association with autophagy	11
ELK1-induced up-regulation of KIF26B promotes cell cycle progression in breast cancer	11
ceRNA network development and tumor-infiltrating immune cell analysis in hepatocellular carcinoma	11
Phase II study of neoadjuvant chemotherapy with S-1 plus oxaliplatin for gastric cancer clinical T4 or N2-3	11
Immune microenvironment-related gene mapping predicts immunochemotherapy response and prognosis in diffuse large B-cell lymphoma	11
The combination therapy of Everolimus and anti-PD-1 improves the antitumor effect by regulating CD8+ T cells in bladder cancer	11
Combination of dasatinib and okadaic acid induces apoptosis and cell cycle arrest by targeting protein phosphatase PP2A in chronic myeloid leukemia cells	11
AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells	11
Correction to: Diosmetin induces apoptosis in ovarian cancer cells by activating reactive oxygen species and inhibiting the Nrf2 pathway	10
Who should be treated with pembrolizumab in addition to standard of care in advanced cervical cancer?	10
Bevacizumab in combination with paclitaxel and platinum for previously treated advanced thymic epithelial tumors	9
Transcription factors linked to the molecular signatures in the development of hepatocellular carcinoma on a cirrhotic background	9
The effects of chemotherapeutic drugs on PD-L1 gene expression in breast cancer cell lines	9
HELZ2 promotes K63-linked polyubiquitination of c-Myc to induce retinoblastoma tumorigenesis	8
RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression	8
Live cell molecular analysis of primary prostate cancer organoids identifies persistent androgen receptor signaling	8
ERCC6L is a biomarker and therapeutic target for non–small cell lung adenocarcinoma	8
Bioymifi, a novel mimetic of TNF-related apoptosis-induced ligand (TRAIL), stimulates eryptosis	8
Isolation and characterization of a novel GRP78-specific single-chain variable fragment (scFv) using ribosome display method	8
Novel molecules as the emerging trends in cancer treatment: an update	8
Correction to: SHARPIN overexpression induces tumorigenesis in human prostate cancer LNCaP, DU145 and PC-3 cells via NF-κB/ERK/Akt signaling pathway	8
Biological activity and molecular docking studies of some new quinolines as potent anticancer agents	8
Analyzing the impact of ATF3 in tumorigenesis and immune cell infiltration of ovarian tumor: a bioinformatics study	8
Glioblastoma recurrent cells switch between ATM and ATR pathway as an alternative strategy to survive radiation stress	8
SOX2 knockdown with siRNA reverses cisplatin resistance in NSCLC by regulating APE1 signaling	8
Blue light induces ROS mediated apoptosis and degradation of AML1-ETO oncoprotein in Kasumi-1 cells	8
WAC, a novel GBM tumor suppressor, induces GBM cell apoptosis and promotes autophagy	8
Molecular targets and therapeutics in chemoresistance of triple-negative breast cancer	7
Identification of key genes in the tumor microenvironment of lung adenocarcinoma	7
Cancer induced bone pain: current management and future perspectives	7
Attitudes, practices and perspectives on imaging strategies in prostate cancer: a national cross-sectional survey involving expert radiation oncologists on behalf of AIRO (Italian association of radio	7
Effects of electroporation on anticancer activity of 5-FU and newly synthesized zinc(II) complex in chemotherapy-resistance human brain tumor cells	7
Combination of resveratrol and BIBR1532 inhibits proliferation of colon cancer cells by repressing expression of LncRNAs	7
CDK9 inhibitors in multiple myeloma: a review of progress and perspectives	7
Upfront metastasis‑directed therapy in oligorecurrent prostate cancer does not decrease the time from initiation of androgen deprivation therapy to castration resistance: in regard to Triggiani et al.	7
Detection of human papillomavirus infection in oral cancers reported at dental facility: assessing the utility of FFPE tissues	7