Cell Stress & Chaperones

Article	Citations
SARS-CoV-2 and Guillain-Barré syndrome: molecular mimicry with human heat shock proteins as potential pathogenic mechanism	99
Human molecular chaperones share with SARS-CoV-2 antigenic epitopes potentially capable of eliciting autoimmunity against endothelial cells: possible role of molecular mimicry in COVID-19	81
The PI3K/Akt signaling axis in Alzheimer’s disease: a valuable target to stimulate or suppress?	73
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia–reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis	58
Small heat shock proteins in neurodegenerative diseases	51
Nrf2/ARE is a key pathway for curcumin-mediated protection of TMJ chondrocytes from oxidative stress and inflammation	47
COVID-19 and heme oxygenase: novel insight into the disease and potential therapies	45
Is COVID-19 a proteiform disease inducing also molecular mimicry phenomena?	44
Central role of 70-kDa heat shock protein in adaptation of plants to drought stress	33
The multifaceted nature of αB-crystallin	33
Crosstalk between endoplasmic reticulum stress and oxidative stress in the progression of diabetic nephropathy	32
Stress and immunity in poultry: light management and nanotechnology as effective immune enhancers to fight stress	30
Small heat-shock proteins and their role in mechanical stress	30
Possible application of H2S-producing compounds in therapy of coronavirus (COVID-19) infection and pneumonia	29
Effect of di(2-ethylhexyl) phthalate on Nrf2-regulated glutathione homeostasis in mouse kidney	29
Structure and function of the co-chaperone protein phosphatase 5 in cancer	28
Human Hsp90 cochaperones: perspectives on tissue-specific expression and identification of cochaperones with similar in vivo functions	28
Psychrophilic Pseudomonas helmanticensis proteome under simulated cold stress	28
Structural aspects of the human small heat shock proteins related to their functional activities	27
COVID-19, acute respiratory distress syndrome (ARDS), and hyperbaric oxygen therapy (HBOT): what is the link?	26
The multiple organs insult and compensation mechanism in mice exposed to hypobaric hypoxia	24
Inhibition of hsa_circ_0002570 suppresses high-glucose–induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-1243/angiomotin axis	23
The interaction of heat shock proteins with cellular membranes: a historical perspective	23
Covid-19, heat shock proteins, and autoimmune bullous diseases: a potential link deserving further attention	22
Diversity in heat shock protein families: functional implications in virus infection with a comprehensive insight of their role in the HIV-1 life cycle	21

Urolithin A induces cell cycle arrest and apoptosis by inhibiting Bcl-2, increasing p53-p21 proteins and reactive oxygen species production in colorectal cancer cells	20
Ebola virus glycoprotein GP1—host cell-surface HSPA5 binding site prediction	19
Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies	19
The mitochondria-targeted antioxidant MitoQ ameliorates myocardial ischemia–reperfusion injury by enhancing PINK1/Parkin-mediated mitophagy in type 2 diabetic rats	19
Peeking from behind the veil of enigma: emerging insights on small heat shock protein structure and function	19
O-GlcNAcylation: the “stress and nutrition receptor” in cell stress response	19
Hydrolyzed camel whey protein alleviated heat stress-induced hepatocyte damage by activated Nrf2/HO-1 signaling pathway and inhibited NF-κB/NLRP3 axis	19
MiR-17-5p-mediated endoplasmic reticulum stress promotes acute myocardial ischemia injury through targeting Tsg101	19
Gambogic acid ameliorates high glucose– and palmitic acid–induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo	18
Lipid chaperones and associated diseases: a group of chaperonopathies defining a new nosological entity with implications for medical research and practice	17
Interaction of HSPA5 (Grp78, BIP) with negatively charged phospholipid membranes via oligomerization involving the N-terminal end domain	17
Exogenous recombinant Hsp70 mediates neuroprotection after photothrombotic stroke	17
Comparative analysis of differential gene expression of HSP40 and HSP70 family isoforms during heat stress and HIV-1 infection in T-cells	17
An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space	16
Human heat shock cognate protein (HSC70/HSPA8) interacts with negatively charged phospholipids by a different mechanism than other HSP70s and brings HSP90 into membranes	15
Mutations in HspB1 and hereditary neuropathies	15
Exported plasmodial J domain protein, PFE0055c, and PfHsp70-x form a specific co-chaperone-chaperone partnership	15
Identification of five small heat shock protein genes in Spodoptera frugiperda and expression analysis in response to different environmental stressors	15
MicroRNA-214-3p aggravates ferroptosis by targeting GPX4 in cisplatin-induced acute kidney injury	15
Structural and functional properties of proteins interacting with small heat shock proteins	15
CIGB-258, a peptide derived from human heat-shock protein 60, decreases hyperinflammation in COVID-19 patients	15
Heat stress promotes lipid accumulation by inhibiting the AMPK-PGC-1α signaling pathway in 3T3-L1 preadipocytes	14
The effect of hyperbaric oxygen on mitochondrial and glycolytic energy metabolism: the caloristasis concept	14
Berberine attenuates mitochondrial dysfunction by inducing autophagic flux in myocardial hypoxia/reoxygenation injury	14
HTR2A promotes the development of cardiac hypertrophy by activating PI3K-PDK1-AKT-mTOR signaling	14
Autologous extracellular Hsp70 exerts a dual role in rheumatoid arthritis	14
Involvement of CDKN1A (p21) in cellular senescence in response to heat and irradiation stress during preimplantation development	13
Direct exposure to mild heat stress stimulates cell viability and heat shock protein expression in primary cultured broiler fibroblasts	13
β-Glucan from Saccharomyces cerevisiae alleviates oxidative stress in LPS-stimulated RAW264.7 cells via Dectin-1/Nrf2/HO-1 signaling pathway	13
Iron depletion with deferoxamine protects bone marrow-derived mesenchymal stem cells against oxidative stress-induced apoptosis	13
Hsp70 affects memory formation and behaviorally relevant gene expression in Drosophila melanogaster	12
Heat shock proteins and the biogenesis of cellular membranes	12
Genome-wide analysis of Hsp70 and Hsp100 gene families in Ziziphus jujuba	12
Inhibition of USP14 induces ER stress–mediated autophagy without apoptosis in lung cancer cell line A549	12
Dynamic changes in blood immune cell composition and function in Holstein and Jersey steers in response to heat stress	12
Chronic heat treatment positively impacts metabolic profile of ovariectomized rats: association with heat shock response pathways	12
Tissue-specific effects of temperature on proteasome function	12
Heat shock protein 90 and NFkB levels in serum and urine in patients with chronic glomerulonephritis	12
Small but mighty: a functional look at bacterial sHSPs	12
Multivalent protein–protein interactions are pivotal regulators of eukaryotic Hsp70 complexes	11
Stress-induced changes in CARF expression determine cell fate to death, survival, or malignant transformation	11
AlphaB-crystallin and breast cancer: role and possible therapeutic strategies	11
Towards an understanding of the role of intrinsic protein disorder on plant adaptation to environmental challenges	11
Elevated seasonal temperature disrupts prooxidant-antioxidant homeostasis and promotes cellular apoptosis in the American oyster, Crassostrea virginica, in the Gulf of Mexico: a field study	11
Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate	11
Increased expression and retention of the secretory chaperone proSAAS following cell stress	10
Neutralizing the free radicals could alleviate the disease severity following an infection by positive strand RNA viruses	10
The role of PSMB5 in sodium arsenite–induced oxidative stress in L-02 cells	10
Elabela blunts doxorubicin-induced oxidative stress and ferroptosis in rat aortic adventitial fibroblasts by activating the KLF15/GPX4 signaling	10
Short-term cold stress and heat shock proteins in the crustacean Artemia franciscana	10

Endoplasmic reticulum-unfolded protein response pathway modulates the cellular response to mitochondrial proteotoxic stress	10
The effects of cold stress on Mytilus species in the natural environment	10
Heat-induced endoplasmic reticulum stress in soleus and gastrocnemius muscles and differential response to UPR pathway in rats	10
Hsp90 chaperone code and the tumor suppressor VHL cooperatively regulate the mitotic checkpoint	9
Gene network analyses support subfunctionalization hypothesis for duplicated hsp70 genes in the Antarctic clam	9
ER stress-related molecules induced by Hantaan virus infection in differentiated THP-1 cells	9
HSP70 as a biomarker of the thin threshold between benefit and injury due to physical exercise when exposed to air pollution	9
Iso-mukaadial acetate and ursolic acid acetate inhibit the chaperone activity of Plasmodium falciparum heat shock protein 70-1	9
Astaxanthin supplementation impacts the cellular HSP expression profile during passive heating	9
Sex differences in COVID-19 mortality: opportunity to develop HSP27 (HSPB1) immunotherapy to treat hyper-inflammation?	8
Cold-inducible RNA-binding protein Cirp, but not Rbm3, may regulate transcript processing and protection in tissues of the hibernating ground squirrel	8
Gambogic acid and gambogenic acid induce a thiol-dependent heat shock response and disrupt the interaction between HSP90 and HSF1 or HSF2	8
HSF-1 displays nuclear stress body formation in multiple tissues in Caenorhabditis elegans upon stress and following the transition to adulthood	8
Effect of Nrf2 signaling pathway on the improvement of intestinal epithelial barrier dysfunction by hyperbaric oxygen treatment after spinal cord injury	8
Transcriptional regulation of small heat shock protein genes by heat shock factor 1 (HSF1) in Liriomyza trifolii under heat stress	8
Circulating heat shock protein 90 (Hsp90) and autoantibodies to Hsp90 are increased in patients with atopic dermatitis	8
The effect of tropisetron on oxidative stress, SIRT1, FOXO3a, and claudin-1 in the renal tissue of STZ-induced diabetic rats	8
The immunopathobiology of T cells in stress condition: a review	8
Tanshinone IIA pretreatment promotes cell survival in human lung epithelial cells under hypoxia via AP-1-Nrf2 transcription factor	8
Coping with harsh heat environments: molecular adaptation of metabolic depression in the intertidal snail Echinolittorina radiata	7
Proteomics study on the protective mechanism of soybean isoflavone against inflammation injury of bovine mammary epithelial cells induced by Streptococcus agalactiae	7
Novel insights into the involvement of mitochondrial fission/fusion in heart failure: From molecular mechanisms to targeted therapies	7
The effect of different atmosphere absolute hyperbaric oxygen on the expression of extracellular histones after traumatic brain injury in rats	7
Autoantibodies to heat shock protein 60, 70, and 90 are not altered in the anti-SARS-CoV-2 IgG-seropositive humans without or with mild symptoms	7
Endoplasmic reticulum stress and unfolded protein accumulation correlate to seizure recurrence in focal cortical dysplasia patients	7
SARS-CoV-2 in patients with cancer: possible role of mimicry of human molecules by viral proteins and the resulting anti-cancer immunity	7
Coronaviruses and stress: from cellular to global	7
Modulation of endoplasmic reticulum stress via sulforaphane-mediated AMPK upregulation against nonalcoholic fatty liver disease in rats	7
Control of stress-induced apoptosis by freezing tolerance-associated wheat proteins during cryopreservation of rat hepatocytes	7
BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes	7
JNK signaling pathway regulates the development of ovaries and synthesis of vitellogenin (Vg) in the swimming crab Portunus trituberculatus	7
Transient receptor potential ankyrin 1 contributes to the lysophosphatidylcholine-induced oxidative stress and cytotoxicity in OLN-93 oligodendrocyte	7
Delineation of temperature-humidity index (THI) as indicator of heat stress in riverine buffaloes (Bubalus bubalis) of a sub-tropical Indian region	6
What artificial intelligence knows about 70 kDa heat shock proteins, and how we will face this ChatGPT era	6
Protein products of nonstop mRNA disrupt nucleolar homeostasis	6
Overexpression of heat shock protein 70 inhibits epithelial-mesenchymal transition and cell migration induced by transforming growth factor-β in A549 cells	6
Kinetic and structural parameters governing Fic-mediated adenylylation/AMPylation of the Hsp70 chaperone, BiP/GRP78	6
Mouse liver is more resistant than skeletal muscle to heat-induced apoptosis	6
Mechanism of miR-455–3 in suppressing epithelial–mesenchymal transition and angiogenesis of non-small cell lung cancer cells	6
Antarctic krill (Euphausia superba) in a warming ocean: thermotolerance and deciphering Hsp70 responses	6
Sequence similarity of HSP65 of Mycobacterium bovis BCG with SARS-CoV-2 spike and nuclear proteins: may it predict an antigen-dependent immune protection of BCG against COVID-19?	6
Heat stress-induced HSP90 expression is dependent on ERK and HSF1 activation in turbot (Scophthalmus maximus) kidney cells	6
Transcription factor Nrf2 as a potential therapeutic target for COVID-19	5
Molecular cloning and characterization of HSP60 gene in domestic pigeons (Columba livia) and differential expression patterns under temperature stress	5
Nutri-stress, mitochondrial dysfunction, and insulin resistance—role of heat shock proteins	5
Molecular characterization and expression patterns of heat shock proteins in Spodoptera littoralis, heat shock or immune response?	5
ACY-1215 suppresses the proliferation and induces apoptosis of chronic myeloid leukemia cells via the ROS/PTEN/Akt pathway	5
Analysis of insect nuclear small heat shock proteins and interacting proteins	5
Studying heat shock proteins through single-molecule mechanical manipulation	5
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury	5
O-GlcNAcylation suppresses TRAP1 activity and promotes mitochondrial respiration	5
Heme oxygenase agonists—fluvoxamine, melatonin—are efficacious therapy for Covid-19	5
Coping with stress in a warming Gulf: the postlarval American lobster’s cellular stress response under future warming scenarios	5
RNA binding motif protein 3 (RBM3) promotes protein kinase B (AKT) activation to enhance glucose metabolism and reduce apoptosis in skeletal muscle of mice under acute cold exposure	5
The effects of β1 and β1+2 adrenergic receptor blockade on the exercise-induced mobilization and ex vivo expansion of virus-specific T cells: implications for cellular therapy and the anti-viral immun	5
The renal antioxidative effect of losartan involves heat shock protein 70 in proximal tubule cells	5
Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability	5
Cloning and expression studies on glutathione S-transferase like-gene in honey bee for its role in oxidative stress	5
Transgenerational transmission of environmental effects in livestock in the age of global warming	5
Comparison between two cryopreservation techniques of human ovarian cortex: morphological aspects and the heat shock response (HSR)	5
The regulation of Akt and FoxO transcription factors during dehydration in the African clawed frog (Xenopus laevis)	5
Antioxidant defense of fish collagen peptides attenuates oxidative stress in gastric mucosa of experimentally ulcer-induced rats	5
Differential expression of nuclear genes encoding mitochondrial proteins from urban and rural populations in Morocco	5
Molecular cloning of heat shock protein 70 and HOP from the freshwater green algae Closterium ehrenbergii and their responses to stress	5
Extracellular Hsp90α stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress	4
The combination of hypoxia and high temperature affects heat shock, anaerobic metabolism, and pentose phosphate pathway key components responses in the white shrimp (Litopenaeus vannamei)	4
Intense immunostaining of heat shock protein 70 within renal interstitium associates with long-term renal survival in an ANCA-associated vasculitis cohort	4
Crosstalk between endoplasmic reticulum and cytosolic unfolded protein response in tomato	4
On barring the vascular gateway against severe COVID-19 disease	4
HSP70 protects H9C2 cells from hypoxia and reoxygenation injury through STIM1/IP3R	4
Correction to: COVID-19 and heme oxygenase: novel insight into the disease and potential therapies	4
Camel whey protein alleviates heat stress-induced liver injury by activating the Nrf2/HO-1 signaling pathway and inhibiting HMGB1 release	4
HSPB5 (αB-crystallin) confers protection against paraquat-induced oxidative stress at the organismal level in a tissue-dependent manner	4
ER-stress-induced secretion of circulating glucose-regulated protein 78kDa (GRP78) ameliorates pulmonary artery smooth muscle cell remodelling	4
Hippo-YAP signaling and SARS-CoV-2 infection: a new mechanistic pathway	4
Mitophagy as a mitochondrial quality control mechanism in myocardial ischemic stress: from bench to bedside	4
Cleavage of HSP90β induced by histone deacetylase inhibitor and proteasome inhibitor modulates cell growth and apoptosis	4
Dynamics of HSPA1A and redox status in the spermatozoa and fluid from different segments of goat epididymis	4
PROGRESS STUDY: Progression of chronic kidney disease in children and heat shock proteins	4
Investigation of inflammation, oxidative stress, and DNA damage in COVID-19 patients	4

CircHSPG2 knockdown attenuates hypoxia-induced apoptosis, inflammation, and oxidative stress in human AC16 cardiomyocytes by regulating the miR-1184/MAP3K2 axis	4
Canine osteosarcoma cells exhibit basal accumulation of multiple chaperone proteins and are sensitive to small molecule inhibitors of GRP78 and heat shock protein function	4
Chaperone proteins: universal roles in surviving environmental stress	4
Novel lncRNA lncRNA001074 participates in the low salinity–induced response in the sea cucumber Apostichopus japonicus by targeting the let-7/NKAα axis	4
G protein–coupled receptor kinase 2 modifies the ability of Caenorhabditis elegans to survive oxidative stress	4
Increased eHSP70-to-iHSP70 ratio in prediabetic and diabetic postmenopausal women: a biomarker of cardiometabolic risk	4
ALDH3B1 protects interfollicular epidermal cells against lipid peroxidation via the NRF2 pathway	4
Coordination of the unfolded protein response during hepatic steatosis identifies CHOP as a specific regulator of hepatocyte ballooning	4
Protective effect of hydrogen sulfide against stress-induced lung injury: involvement of Nrf2, NFκB/iNOS, and HIF-1α signaling pathways	4
Serum levels of anti-heat shock protein 27 antibodies in patients with chronic liver disease	3
Antioxidant effects of bis-indole alkaloid indigo and related signaling pathways in the experimental model of Duchenne muscular dystrophy	3
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells	3
Stress proteins as predictors of COVID-19 outcomes	3
J-domain proteins: From molecular mechanisms to diseases	3
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs	3
Purification and biochemical characterization of Msi3, an essential Hsp110 molecular chaperone in Candida albicans	3
Cyst viability and stress tolerance upon heat shock protein 70 knockdown in the brine shrimp Artemia franciscana	3
The environmental cellular stress response: the intertidal as a multistressor model	3
Molecular characterization of six heat shock protein 70 genes from Arma chinensis and their expression patterns in response to temperature stress	3
Molecular chaperone function of three small heat-shock proteins from a model probiotic species	3
Eukaryotic response to hypothermia in relation to integrated stress responses	3
The Keap1 signaling in the regulation of HSP90 pathway	3
Regulation of the unfolded protein response during dehydration stress in African clawed frogs, Xenopus laevis	3
Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution	3
RETRACTED ARTICLE: Changes in parameters of biochemical and oxidative stress in university students during and after examinations	3
Depletion of eukaryotic initiation factor 5B (eIF5B) reprograms the cellular transcriptome and leads to activation of endoplasmic reticulum (ER) stress and c-Jun N-terminal kinase (JNK)	3
Elevation of major constitutive heat shock proteins is heat shock factor independent and essential for establishment and growth of Lgl loss and Yorkie gain-mediated tumors in Drosophila	3