Addiction Biology

Article	Citations
Sex differences in the acute effects of oral and vaporized cannabis among healthy adults	52
Nicotine e‐cigarette vapor inhalation and self‐administration in a rodent model: Sex‐ and nicotine delivery‐specific effects on metabolism and behavior	37
Intermittent self‐administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system	37
Repeated low doses of LSD in healthy adults: A placebo‐controlled, dose–response study	29
Epigenetics of alcohol use disorder—A review of recent advances in DNA methylation profiling	26
Brain imaging of cannabinoid type I (CB1) receptors in women with cannabis use disorder and male and female healthy controls	26
Neural correlates of problematic gaming in adolescents: A systematic review of structural and functional magnetic resonance imaging studies	26
Fos‐expressing neuronal ensemble in rat ventromedial prefrontal cortex encodes cocaine seeking but not food seeking in rats	25
Common neurofunctional dysregulations characterize obsessive–compulsive, substance use, and gaming disorders—An activation likelihood meta‐analysis of functional imaging studies	25
Closing the brain–heart loop: Towards more holistic models of addiction and addiction recovery	24
A neural mechanism of the relationship between impulsivity and emotion dysregulation in patients with Internet gaming disorder	23
Resting activity of the hippocampus and amygdala in obese individuals predicts their response to food cues	22
Role of orbitofrontal cortex in incubation of oxycodone craving in male rats	22
Mapping cortical and subcortical asymmetries in substance dependence: Findings from the ENIGMA Addiction Working Group	22
Gut dysbiosis associated with the rats' responses in methamphetamine‐induced conditioned place preference	21
Dorsal and ventral striatum activity in individuals with buying‐shopping disorder during cue‐exposure: A functional magnetic resonance imaging study	21
Resting‐state connectome‐based support‐vector‐machine predictive modeling of internet gaming disorder	20
Optogenetic brain‐stimulation reward: A new procedure to re‐evaluate the rewarding versus aversive effects of cannabinoids in dopamine transporter‐Cre mice	19
Untargeted metabolomics analysis by gas chromatography/time‐of‐flight mass spectrometry of human serum from methamphetamine abusers	19
No changes in the oxytocin system in alcohol‐dependent female rodents and humans: Towards a sex‐specific psychopharmacology in alcoholism	19
Mu opioid receptors on vGluT2‐expressing glutamatergic neurons modulate opioid reward	19
Reduced frontostriatal functional connectivity and associations with severity of Internet gaming disorder	19
Innate gut microbiota predisposes to high alcohol consumption	18
A meta‐analysis of tract‐based spatial statistics studies examining white matter integrity in cocaine use disorder	18
The future of translational research on alcohol use disorder	18

Addiction Research Unit: Affective and cognitive mechanisms of specific Internet‐use disorders	18
Dopamine neurons gate the intersection of cocaine use, decision making, and impulsivity	18
Public perception of laboratory animal testing: Historical, philosophical, and ethical view	17
Lower prefrontal cortical synaptic vesicle binding in cocaine use disorder: An exploratory 11C‐UCB‐J positron emission tomography study in humans	17
Sex differences in acute cannabis effects revisited: Results from two randomized, controlled trials	17
Sustained brain response to repeated drug cues is associated with poor drug‐use outcomes	17
Individual differences in the engagement of habitual control over alcohol seeking predict the development of compulsive alcohol seeking and drinking	16
Associations between alcohol use and accelerated biological ageing	16
Circular RNA expression alteration identifies a novel circulating biomarker in serum exosomal for detection of alcohol dependence	16
Behavioral effects of four novel synthetic cathinone analogs in rodents	16
Potentiation of glutamatergic synaptic transmission onto lateral habenula neurons following early life stress and intravenous morphine self‐administration in rats	16
Sugar intake and craving during alcohol withdrawal in alcohol use disorder inpatients	16
A closer look at alcohol‐induced changes in the ghrelin system: novel insights from preclinical and clinical data	16
Effects of cannabidiol in cannabis flower: Implications for harm reduction	16
The role of withdrawal in mesocorticolimbic drug cue reactivity in opioid use disorder	15
More than just statics: Temporal dynamic changes of intrinsic brain activity in cigarette smoking	15
Multimodal MRI data fusion reveals distinct structural, functional and neurochemical correlates of heavy cannabis use	15
Chronic opioid exposure differentially modulates oxycodone self‐administration in male and female rats	15
Alcohol withdrawal symptoms predict corticostriatal dysfunction that is reversed by prazosin treatment in alcohol use disorder	15
Extreme phenotypic diversity in operant response to intravenous cocaine or saline infusion in the hybrid mouse diversity panel	15
Role of prefrontal cortex projections to the nucleus accumbens core in mediating the effects of ceftriaxone on cue‐induced cocaine seeking	14
Effects of 5‐HT2A receptor stimulation on economic demand for fentanyl after intermittent and continuous access self‐administration in male rats	14
Associations between the CADM2 gene, substance use, risky sexual behavior, and self‐control: A phenome‐wide association study	14
Glucagon‐like peptide‐1 receptor agonist, liraglutide, reduces heroin self‐administration and drug‐induced reinstatement of heroin‐seeking behaviour in rats	14
Increased network centrality of the anterior insula in early abstinence from alcohol	13
Impaired motor cortical plasticity associated with cannabis use disorder in young adults	13
Oral oxycodone self‐administration leads to features of opioid misuse in male and female mice	13
Maternal separation increases cocaine intake through a mechanism involving plasticity in glutamate signalling	13
Dual methylation and hydroxymethylation study of alcohol use disorder	13
Connectome‐based prediction of craving for gaming in internet gaming disorder	13
Baclofen decreases compulsive alcohol drinking in rats characterized by reduced levels of GAT‐3 in the central amygdala	13
Prenatal opioid exposure reprograms the behavioural response to future alcohol reward	12
Voluntary alcohol binge‐drinking in adolescent C57Bl6 mice induces delayed appearance of behavioural defects in both males and females	12
Akt and its phosphorylation in nucleus accumbens mediate heroin‐seeking behavior induced by cues in rats	12
Deletion of Tlr3 reduces acute tolerance to alcohol and alcohol consumption in the intermittent access procedure in male mice	12
Calcium‐permeable AMPA receptor activity and GluA1 trafficking in the basolateral amygdala regulate operant alcohol self‐administration	12
Stress‐induced escalation of alcohol self‐administration, anxiety‐like behavior, and elevated amygdala Avp expression in a susceptible subpopulation of rats	12
Glutamatergic input from the insula to the ventral bed nucleus of the stria terminalis controls reward‐related behavior	12
Adolescent social isolation induced alterations in nucleus accumbens glutamate signalling	12
Interactions between reinforcement history and drug‐primed reinstatement: Studies with MDPV and mixtures of MDPV and caffeine	11
Convergent cross‐sectional and longitudinal evidence for gaming‐cue specific posterior parietal dysregulations in early stages of internet gaming disorder	11
Low‐dose polypharmacology targeting dopamine D1 and D3 receptors reduces cue‐induced relapse to heroin seeking in rats	11
Altered intrinsic connectivity distribution in internet gaming disorder and its associations with psychotherapy treatment outcomes	11
Sex‐specific plasticity in CRF regulation of inhibitory control in central amygdala CRF1 neurons after chronic voluntary alcohol drinking	11
Effects of a selective long‐acting amylin receptor agonist on alcohol consumption, food intake and body weight in male and female rats	11
Gonadal hormones and sex chromosome complement differentially contribute to ethanol intake, preference, and relapse‐like behaviour in four core genotypes mice	11
Interoceptive signaling in alcohol cognitive biases: Role of family history and alliesthetic components	11
Acute alcohol intoxication modulates the temporal dynamics of resting electroencephalography networks	11
Identifying a novel biological mechanism for alcohol addiction associated with circRNA networks acting as potential miRNA sponges	11
Are methamphetamine users compulsive? Faulty reinforcement learning, not inflexibility, underlies decision making in people with methamphetamine use disorder	11

Machine learning with neuroimaging biomarkers: Application in the diagnosis and prediction of drug addiction	11
Susceptibility to interference between Pavlovian and instrumental control is associated with early hazardous alcohol use	11
Effects of pituitary adenylate cyclase‐activating polypeptide isoforms in nucleus accumbens subregions on ethanol drinking	10
Impaired cognitive flexibility and heightened urgency are associated with increased alcohol consumption in rodent models of excessive drinking	10
Modafinil rescues repeated morphine‐induced synaptic and behavioural impairments via activation of D1R–ERK–CREB pathway in medial prefrontal cortex	10
A randomised, double‐blind study investigating the relationship between early childhood trauma and the rewarding effects of morphine	10
Oxytocin prevents cue‐induced reinstatement of oxycodone seeking: Involvement of DNA methylation in the hippocampus	10
Chemogenetic inhibition of corticostriatal circuits reduces cued reinstatement of methamphetamine seeking	10
Brain dysfunction of methamphetamine‐associated psychosis in resting state: Approaching schizophrenia and critical role of right superior temporal deficit	10
Cerebellar thickness changes associated with heavy cannabis use: A 3‐year longitudinal study	10
Repetitive transcranial magnetic stimulation modulates coupling among large‐scale brain networks in heroin‐dependent individuals: A randomized resting‐state functional magnetic resonance imaging study	10
Adolescent alcohol use disrupts functional neurodevelopment in sensation seeking girls	10
Persistent dependent behaviour is accompanied by dynamic switching between the ventral and dorsal striatal connections in internet gaming disorder	10
Classic psychedelics and alcohol use disorders: A systematic review of human and animal studies	10
CBD‐mediated regulation of heroin withdrawal‐induced behavioural and molecular changes in mice	9
Disruption of relapse to alcohol seeking by aversive counterconditioning following memory retrieval	9
Altered neural responses to missed chance contribute to the risk‐taking behaviour in individuals with Internet gaming disorder	9
Modulation of dopamine release by ethanol is mediated by atypical GABAA receptors on cholinergic interneurons in the nucleus accumbens	9
Dysregulated kappa‐opioid receptors in the medial prefrontal cortex contribute to working memory deficits in alcohol dependence	9
5HT‐2C agonist lorcaserin decreases cannabis self‐administration in daily cannabis smokers	9
Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial	9
Energy sensors in drug addiction: A potential therapeutic target	9
Shared network‐level functional alterations across substance use disorders: A multi‐level kernel density meta‐analysis of resting‐state functional connectivity studies	9
Cannabis use selectively modulates circulating biomarkers in the blood of schizophrenia patients	9
Exercise craving potentiates excitatory inputs to ventral tegmental area dopaminergic neurons	9
The serotonin 2A receptor agonist TCB‐2 attenuates heavy alcohol drinking and alcohol‐induced midbrain inhibitory plasticity	9
The serotonin 2C receptor agonist lorcaserin, alone and in combination with the opioid receptor antagonist naltrexone, attenuates binge‐like ethanol drinking	9
Genetic liability for substance use associated with medical comorbidities in electronic health records of African‐ and European‐ancestry individuals	9
Assessing effect of long‐term abstinence on coupling of three core brain networks in male heroin addicts: A resting‐state functional magnetic resonance imaging study	9
Repeated nicotine exposure increases the intracellular interaction between ERK‐mGluR5 in the nucleus accumbens more in adult than adolescent rats	9
Cocaine memory reactivation induces functional adaptations within parvalbumin interneurons in the rat medial prefrontal cortex	9
A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue‐induced cocaine craving following prolonged abstinence	9
Cannabis use does not impact on type 2 diabetes: A two‐sample Mendelian randomization study	8
Changes in the metabolic profile of human male postmortem frontal cortex and cerebrospinal fluid samples associated with heavy alcohol use	8
Incubation of alcohol craving as it naturally occurs in a developmentally diverse sample of dependent and nondependent drinkers	8
Repeated exposure to cocaine during adolescence enhances the rewarding threshold for cocaine‐conditioned place preference in adulthood	8
Disentangling craving‐ and valence‐related brain responses to smoking cues in individuals with nicotine use disorder	8
Changes in ALFF and ReHo values in methamphetamine abstinent individuals based on the Harvard‐Oxford atlas: A longitudinal resting‐state fMRI study	8
MicroRNA‐132 is involved in morphine dependence via modifying the structural plasticity of the dentate gyrus neurons in rats	8
Neural representation of prediction error signals in substance users	8
Paternal alcohol exposure reduces acquisition of operant alcohol self‐administration and affects Bdnf DNA methylation in male and female offspring	8
Alcohol‐induced aggression in Drosophila	8
Differential expression of miR‐1249‐3p and miR‐34b‐5p between vulnerable and resilient phenotypes of cocaine addiction	8
The glucagon‐like peptide‐1 system is modulated by acute and chronic alcohol exposure: Findings from human laboratory experiments and a post‐mortem brain study	8
Sex difference in the vulnerability to hippocampus plasticity impairment after binge‐like ethanol exposure in adolescent rat: Is estrogen the key?	8
Resting state hypothalamic and dorsomedial prefrontal cortical connectivity of the periaqueductal gray in cocaine addiction	8
Test–retest reliability of neural alcohol cue‐reactivity: Is there light at the end of the magnetic resonance imaging tube?	8
Alcohol use disorder in the COVID‐19 era: Position paper of the Italian Society on Alcohol (SIA)	8
Nalmefene alleviates the neuroimmune response to repeated binge‐like ethanol exposure: A TSPO PET imaging study in adolescent rats	8
The effects of morphine withdrawal and conditioned withdrawal on memory consolidation and c‐Fos expression in the central amygdala	8
Stress induces reinstatement of extinguished cocaine conditioned place preference by a sequential signaling via neuropeptide S, orexin, and endocannabinoid	8
Bidirectional sex‐dependent regulation of α6 and β3 nicotinic acetylcholine receptors by protein kinase Cε	8
Chronic ethanol exposure induced anxiety‐like behaviour by altering gut microbiota and GABA system	8
The GPR88 agonist RTI‐13951‐33 reduces alcohol drinking and seeking in mice	7
How alcohol makes the epigenetic clock tick faster and the clock reversing effect of abstinence	7
Unraveling the role of cigarette use in neural cannabis cue reactivity in heavy cannabis users	7
Repeated blast mild traumatic brain injury and oxycodone self‐administration produce interactive effects on neuroimaging outcomes	7
Activation of trace amine‐associated receptor 1 attenuates nicotine withdrawal‐related effects	7
Locomotor sensitization modulates voluntary self‐administration of methamphetamine in Drosophila melanogaster	7
Translating preclinical models of alcohol seeking and consumption into the human laboratory using intravenous alcohol self‐administration paradigms	7
Cocaine hydrolase blocks cocaine‐induced dopamine transporter trafficking to the plasma membrane	7
Alcohol's effects on the mouse brain are modulated by age and sex	7
Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte‐mediated glutamate clearance in the dCA1	7
Effects of substance use disorder on oxidative and antioxidative stress markers: A systematic review and meta‐analysis	7
Increased striatal functional connectivity is associated with improved smoking cessation outcomes: A preliminary study	7
Increases in endogenous progesterone attenuate smoking in a cohort of nontreatment seeking women: An exploratory prospective study	7
GABAergic projections to the ventral tegmental area govern cocaine‐conditioned reward	7
The impact of levamisole and alcohol on white matter microstructure in adult chronic cocaine users	7
FGF2 is an endogenous regulator of alcohol reward and consumption	7
The Toll‐like receptor 7 agonist imiquimod increases ethanol self‐administration and induces expression of Toll‐like receptor related genes	7
Ethanol produces multiple electrophysiological effects on ventral tegmental area neurons in freely moving rats	7
Sulphated dehydroepiandrosterone serum levels are reduced in women with alcohol use disorder and correlate negatively with craving: A sex‐separated cross‐sectional and longitudinal study	7
Brain volume changes after long‐term injectable opioid treatment: A longitudinal voxel‐based morphometry study	7
Impaired hypothalamic feedback dysregulates brain glucocorticoid signaling in genetically‐selected Marchigian Sardinian alcohol‐preferring rats	7
Sex‐specific metabolic signatures in methamphetamine addicts	7
Heroin‐assisted treatment of heroin‐addicted patients normalizes regulatory T cells but does not restore CD4+ T cell proliferation	7
Neurometabolic alterations in the nucleus accumbens of smokers assessed with 1H magnetic resonance spectroscopy: The role of glutamate and neuroinflammation	7
Bipolar disorder and cannabis use: A bidirectional two‐sample Mendelian randomization study	7
Differential brain responses to alcohol‐related and natural rewards are associated with alcohol use and problems: Evidence for reward dysregulation	7
Sex‐specific role for prefrontal cortical protein interacting with C kinase 1 in cue‐induced cocaine seeking	7

Alcohol dependence activates ventral tegmental area projections to central amygdala in male mice and rats	7
The dopaminergic alterations induced by 4‐F‐PCP and 4‐Keto‐PCP may enhance their drug‐induced rewarding and reinforcing effects: Implications for abuse	7
Nicotine abolishes memory‐related synaptic strengthening and promotes synaptic depression in the neurogenic dentate gyrus of miR‐132/212 knockout mice	7
Compensatory neuroadaptation to binge drinking: Human evidence for allostasis	7
Cocaine experience induces functional adaptations in astrocytes: Implications for synaptic plasticity in the nucleus accumbens shell	7
Long‐term consequences of alcohol use in early adolescent mice: Focus on neuroadaptations in GR, CRF and BDNF	7
Combined effects of quetiapine and opioids: A study of autopsy cases, drug users and sedation in rats	7
Disturbed sensory physiology underlies poor balance and disrupts activities of daily living in alcohol use disorder	7