OOIR: Observatory of International Research

Papers

(The TQCC of Addiction Biology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Nicotine e‐cigarette vapor inhalation and self‐administration in a rodent model: Sex‐ and nicotine delivery‐specific effects on metabolism and behavior	40
Repeated low doses of LSD in healthy adults: A placebo‐controlled, dose–response study	38
Common neurofunctional dysregulations characterize obsessive–compulsive, substance use, and gaming disorders—An activation likelihood meta‐analysis of functional imaging studies	31
Epigenetics of alcohol use disorder—A review of recent advances in DNA methylation profiling	31
Neural correlates of problematic gaming in adolescents: A systematic review of structural and functional magnetic resonance imaging studies	30
Brain imaging of cannabinoid type I (CB₁) receptors in women with cannabis use disorder and male and female healthy controls	29
Mapping cortical and subcortical asymmetries in substance dependence: Findings from the ENIGMA Addiction Working Group	27
Innate gut microbiota predisposes to high alcohol consumption	26
Gut dysbiosis associated with the rats' responses in methamphetamine‐induced conditioned place preference	26
Public perception of laboratory animal testing: Historical, philosophical, and ethical view	25
Addiction Research Unit: Affective and cognitive mechanisms of specific Internet‐use disorders	25
Dorsal and ventral striatum activity in individuals with buying‐shopping disorder during cue‐exposure: A functional magnetic resonance imaging study	24
Resting activity of the hippocampus and amygdala in obese individuals predicts their response to food cues	23
Individual differences in the engagement of habitual control over alcohol seeking predict the development of compulsive alcohol seeking and drinking	23
Associations between alcohol use and accelerated biological ageing	22
Optogenetic brain‐stimulation reward: A new procedure to re‐evaluate the rewarding versus aversive effects of cannabinoids in dopamine transporter‐Cre mice	22
Resting‐state connectome‐based support‐vector‐machine predictive modeling of internet gaming disorder	22
Dopamine neurons gate the intersection of cocaine use, decision making, and impulsivity	22
Reduced frontostriatal functional connectivity and associations with severity of Internet gaming disorder	21
Sex differences in acute cannabis effects revisited: Results from two randomized, controlled trials	21
Alcohol withdrawal symptoms predict corticostriatal dysfunction that is reversed by prazosin treatment in alcohol use disorder	21
Potentiation of glutamatergic synaptic transmission onto lateral habenula neurons following early life stress and intravenous morphine self‐administration in rats	21
Lower prefrontal cortical synaptic vesicle binding in cocaine use disorder: An exploratory ¹¹C‐UCB‐J positron emission tomography study in humans	21
Untargeted metabolomics analysis by gas chromatography/time‐of‐flight mass spectrometry of human serum from methamphetamine abusers	20
Prenatal opioid exposure reprograms the behavioural response to future alcohol reward	19

Sustained brain response to repeated drug cues is associated with poor drug‐use outcomes	19
Behavioral effects of four novel synthetic cathinone analogs in rodents	19
More than just statics: Temporal dynamic changes of intrinsic brain activity in cigarette smoking	19
Multimodal MRI data fusion reveals distinct structural, functional and neurochemical correlates of heavy cannabis use	19
Associations between theCADM2gene, substance use, risky sexual behavior, and self‐control: A phenome‐wide association study	19
Classic psychedelics and alcohol use disorders: A systematic review of human and animal studies	18
Oral oxycodone self‐administration leads to features of opioid misuse in male and female mice	18
Circular RNA expression alteration identifies a novel circulating biomarker in serum exosomal for detection of alcohol dependence	18
A closer look at alcohol‐induced changes in the ghrelin system: novel insights from preclinical and clinical data	18
Effects of cannabidiol in cannabis flower: Implications for harm reduction	18
Baclofen decreases compulsive alcohol drinking in rats characterized by reduced levels of GAT‐3 in the central amygdala	17
Connectome‐based prediction of craving for gaming in internet gaming disorder	16
Extreme phenotypic diversity in operant response to intravenous cocaine or saline infusion in the hybrid mouse diversity panel	16
Glucagon‐like peptide‐1 receptor agonist, liraglutide, reduces heroin self‐administration and drug‐induced reinstatement of heroin‐seeking behaviour in rats	16
Chronic opioid exposure differentially modulates oxycodone self‐administration in male and female rats	16
Increased network centrality of the anterior insula in early abstinence from alcohol	15
Dual methylation and hydroxymethylation study of alcohol use disorder	15
Adolescent social isolation induced alterations in nucleus accumbens glutamate signalling	15
The role of withdrawal in mesocorticolimbic drug cue reactivity in opioid use disorder	15
Brain dysfunction of methamphetamine‐associated psychosis in resting state: Approaching schizophrenia and critical role of right superior temporal deficit	14
Stress‐induced escalation of alcohol self‐administration, anxiety‐like behavior, and elevated amygdala Avp expression in a susceptible subpopulation of rats	14
Shared network‐level functional alterations across substance use disorders: A multi‐level kernel density meta‐analysis of resting‐state functional connectivity studies	14
Machine learning with neuroimaging biomarkers: Application in the diagnosis and prediction of drug addiction	14
Are methamphetamine users compulsive? Faulty reinforcement learning, not inflexibility, underlies decision making in people with methamphetamine use disorder	14
Akt and its phosphorylation in nucleus accumbens mediate heroin‐seeking behavior induced by cues in rats	14
Susceptibility to interference between Pavlovian and instrumental control is associated with early hazardous alcohol use	13
Repetitive transcranial magnetic stimulation modulates coupling among large‐scale brain networks in heroin‐dependent individuals: A randomized resting‐state functional magnetic resonance imaging study	13
Chemogenetic inhibition of corticostriatal circuits reduces cued reinstatement of methamphetamine seeking	13
Gonadal hormones and sex chromosome complement differentially contribute to ethanol intake, preference, and relapse‐like behaviour in four core genotypes mice	13
Changes in brain structure and function following chronic exposure to inhaled vaporised cannabis during periadolescence in female and male mice: A multimodal MRI study	13
Altered neural responses to missed chance contribute to the risk‐taking behaviour in individuals with Internet gaming disorder	13
The glucagon‐like peptide‐1 system is modulated by acute and chronic alcohol exposure: Findings from human laboratory experiments and a post‐mortem brain study	13
Identifying a novel biological mechanism for alcohol addiction associated with circRNA networks acting as potential miRNA sponges	13
Voluntary alcohol binge‐drinking in adolescent C57Bl6 mice induces delayed appearance of behavioural defects in both males and females	13
Cocaine experience induces functional adaptations in astrocytes: Implications for synaptic plasticity in the nucleus accumbens shell	12
Calcium‐permeable AMPA receptor activity and GluA1 trafficking in the basolateral amygdala regulate operant alcohol self‐administration	12
Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial	12
Sex‐specific plasticity in CRF regulation of inhibitory control in central amygdala CRF1 neurons after chronic voluntary alcohol drinking	12
Modulation of dopamine release by ethanol is mediated by atypical GABA_A receptors on cholinergic interneurons in the nucleus accumbens	12
CBD‐mediated regulation of heroin withdrawal‐induced behavioural and molecular changes in mice	12
Impaired cognitive flexibility and heightened urgency are associated with increased alcohol consumption in rodent models of excessive drinking	12
A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue‐induced cocaine craving following prolonged abstinence	12
Acute alcohol intoxication modulates the temporal dynamics of resting electroencephalography networks	11
Bipolar disorder and cannabis use: A bidirectional two‐sample Mendelian randomization study	11
Effects of pituitary adenylate cyclase‐activating polypeptide isoforms in nucleus accumbens subregions on ethanol drinking	11
Exercise craving potentiates excitatory inputs to ventral tegmental area dopaminergic neurons	11
Test–retest reliability of neural alcohol cue‐reactivity: Is there light at the end of the magnetic resonance imaging tube?	11
Changes in the metabolic profile of human male postmortem frontal cortex and cerebrospinal fluid samples associated with heavy alcohol use	11
Persistent dependent behaviour is accompanied by dynamic switching between the ventral and dorsal striatal connections in internet gaming disorder	11
Low‐dose polypharmacology targeting dopamine D1 and D3 receptors reduces cue‐induced relapse to heroin seeking in rats	11

Cannabis use selectively modulates circulating biomarkers in the blood of schizophrenia patients	11
Disentangling craving‐ and valence‐related brain responses to smoking cues in individuals with nicotine use disorder	11
Inhibition of PSD95‐nNOS protein–protein interactions decreases morphine reward and relapse vulnerability in rats	11
Genetic liability for substance use associated with medical comorbidities in electronic health records of African‐ and European‐ancestry individuals	11
Modafinil rescues repeated morphine‐induced synaptic and behavioural impairments via activation of D1R–ERK–CREB pathway in medial prefrontal cortex	11
A randomised, double‐blind study investigating the relationship between early childhood trauma and the rewarding effects of morphine	11
Chronic ethanol exposure induced anxiety‐like behaviour by altering gut microbiota and GABA system	11
Oxytocin prevents cue‐induced reinstatement of oxycodone seeking: Involvement of DNA methylation in the hippocampus	10
Brain volume changes after long‐term injectable opioid treatment: A longitudinal voxel‐based morphometry study	10
Effects of substance use disorder on oxidative and antioxidative stress markers: A systematic review and meta‐analysis	10
Differential brain responses to alcohol‐related and natural rewards are associated with alcohol use and problems: Evidence for reward dysregulation	10
5HT‐2C agonist lorcaserin decreases cannabis self‐administration in daily cannabis smokers	10
Activation of trace amine‐associated receptor 1 attenuates nicotine withdrawal‐related effects	10
Long‐term consequences of alcohol use in early adolescent mice: Focus on neuroadaptations in GR, CRF and BDNF	10
Assessing effect of long‐term abstinence on coupling of three core brain networks in male heroin addicts: A resting‐state functional magnetic resonance imaging study	10
Dysregulated kappa‐opioid receptors in the medial prefrontal cortex contribute to working memory deficits in alcohol dependence	10
Resting state hypothalamic and dorsomedial prefrontal cortical connectivity of the periaqueductal gray in cocaine addiction	10
The serotonin 2C receptor agonist lorcaserin, alone and in combination with the opioid receptor antagonist naltrexone, attenuates binge‐like ethanol drinking	10
Alcohol's effects on the mouse brain are modulated by age and sex	10
Daily and intermittent smoking are associated with low prefrontal volume and low concentrations of prefrontal glutamate, creatine, myo‐inositol, and N‐acetylaspartate	10
GABAergic projections to the ventral tegmental area govern cocaine‐conditioned reward	10
Hyperbolic discounting rates and risk for problematic alcohol use in youth enrolled in the Adolescent Brain and Cognitive Development study	9
Disturbed sensory physiology underlies poor balance and disrupts activities of daily living in alcohol use disorder	9
GluA2‐lacking AMPA receptors in the nucleus accumbens core and shell contribute to the incubation of oxycodone craving in male rats	9
The Toll‐like receptor 7 agonist imiquimod increases ethanol self‐administration and induces expression of Toll‐like receptor related genes	9
Reduced structural connectivity of the amygdala is associated with childhood trauma in adult patients with alcohol use disorder	9
Interactions between impulsivity and MDPV self‐administration in rats	9
Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte‐mediated glutamate clearance in the dCA1	9
How alcohol makes the epigenetic clock tick faster and the clock reversing effect of abstinence	9
MicroRNA‐132 is involved in morphine dependence via modifying the structural plasticity of the dentate gyrus neurons in rats	9
The serotonin 2A receptor agonist TCB‐2 attenuates heavy alcohol drinking and alcohol‐induced midbrain inhibitory plasticity	9
Alcohol use disorder in the COVID‐19 era: Position paper of the Italian Society on Alcohol (SIA)	9
Differential expression of miR‐1249‐3p and miR‐34b‐5p between vulnerable and resilient phenotypes of cocaine addiction	9
Changes in ALFF and ReHo values in methamphetamine abstinent individuals based on the Harvard‐Oxford atlas: A longitudinal resting‐state fMRI study	9
Neural representation of prediction error signals in substance users	9
Repeated blast mild traumatic brain injury and oxycodone self‐administration produce interactive effects on neuroimaging outcomes	9
Effect of chronic ethanol consumption in rhesus macaques on the nucleus accumbens core transcriptome	8
FGF2 is an endogenous regulator of alcohol reward and consumption	8
Paternal alcohol exposure reduces acquisition of operant alcohol self‐administration and affects Bdnf DNA methylation in male and female offspring	8
Combined effects of quetiapine and opioids: A study of autopsy cases, drug users and sedation in rats	8
Low‐dose alcohol: Interoceptive and molecular effects and the role of dentate gyrus in rats	8
The GPR88 agonist RTI‐13951‐33 reduces alcohol drinking and seeking in mice	8
Posterior fronto‐medial atrophy reflects decreased loss aversion, but not executive impairment, in alcohol use disorder	8
Fos‐expressing neuronal ensembles in rat infralimbic cortex encode initial and maintained oxycodone seeking in rats	8
Embryonic ethanol exposure induces ectopic Hcrt and MCH neurons outside hypothalamus in rats and zebrafish: Role in ethanol‐induced behavioural disturbances	8
Alcohol‐induced aggression in Drosophila	8
Cocaine hydrolase blocks cocaine‐induced dopamine transporter trafficking to the plasma membrane	8
Structural correlates of sensorimotor dysfunction in heavy cannabis users	8
Acute nicotine treatment enhances compulsive‐like remifentanil self‐administration that persists despite contextual punishment	8
Neurometabolic alterations in the nucleus accumbens of smokers assessed with ¹H magnetic resonance spectroscopy: The role of glutamate and neuroinflammation	8
Stress induces reinstatement of extinguished cocaine conditioned place preference by a sequential signaling via neuropeptide S, orexin, and endocannabinoid	8
The dopaminergic alterations induced by 4‐F‐PCP and 4‐Keto‐PCP may enhance their drug‐induced rewarding and reinforcing effects: Implications for abuse	8
Similarities and differences between internet gaming disorder and tobacco use disorder: A large‐scale network study	8
Results from a randomized, double‐blind, placebo‐controlled, crossover, multimodal‐MRI pilot study of gabapentin for co‐occurring bipolar and cannabis use disorders	8
"It's a beer!": Brain functional hyperconnectivity during processing of alcohol‐related images in young binge drinkers	8
Heroin‐assisted treatment of heroin‐addicted patients normalizes regulatory T cells but does not restore CD4⁺ T cell proliferation	8
Role of suppressing GLT‐1 and xCT in ceftriaxone‐induced attenuation of relapse‐like alcohol drinking in alcohol‐preferring rats	8
Repeated exposure to cocaine during adolescence enhances the rewarding threshold for cocaine‐conditioned place preference in adulthood	8
Sex difference in the vulnerability to hippocampus plasticity impairment after binge‐like ethanol exposure in adolescent rat: Is estrogen the key?	8
Sex‐specific role for prefrontal cortical protein interacting with C kinase 1 in cue‐induced cocaine seeking	8