OOIR: Observatory of International Research

Papers

(The TQCC of Human Reproduction Update is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Maternal and perinatal outcomes in twin pregnancies following assisted reproduction: a systematic review and meta-analysis involving 802 462 pregnancies	580
Building a human pluripotent stem cell-based gonadal niche: improving in vitro systems with in vivo insigh	176
The pathophysiological role of estrogens in the initial stages of pregnancy: molecular mechanisms and clinical implications for pregnancy outcome from the periconceptional period to end of the first t	145
BMI in children aged 1–18 years conceived after ART with fresh and frozen embryo transfer: a systematic review and meta-analyses	141
Iron overload disorders in adults: a comprehensive review of gonadal function, reproductive, and sexual health	118
Ultrasonographic criteria in the diagnosis of polycystic ovary syndrome: a systematic review and diagnostic meta-analysis	117
What do we mean by preconception health and preconception care in research and policy? A systematic review	116
Functional hypothalamic amenorrhoea and polycystic ovarian morphology: a narrative review about an intriguing association	110
The complicated ART of finding consensus on family-building health policy: a comment on the IFFS consensus document	108
Total fertilization failure after ICSI: insights into pathophysiology, diagnosis, and management through artificial oocyte activation	107
What is the optimal GnRH antagonist protocol for ovarian stimulation during ART treatment? A systematic review and network meta-analysis	106
Preconception lifestyle interventions for women—a systematic review and meta-analysis of intervention characteristics and behaviour change techniques	96
Driving factors in treatment decision-making of patients seeking medical assistance for infertility: a systematic review	89
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries	88
Reproductive ability in survivors of childhood, adolescent, and young adult Hodgkin lymphoma: a review	85
Sperm mitochondrial DNA copy number: a marker of male fertility and reproductive success	79
Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing	77
RNA modifications in female reproductive physiology and disease: emerging roles and clinical implications	75
Reply: Artificial cycle frozen embryo transfer and obstetric adverse outcomes: association or causation?	70
Intrauterine human chorionic gonadotropin administration before embryo transfer (IHABT): an individual participant data meta-analysis of randomized controlled trials	65
Assessing the influence of preconception diet on female fertility: a systematic scoping review of observational studies	61
What is the expected live birth rate per thawed oocyte?	58
COVID-19 in pregnant women: a systematic review and meta-analysis on the risk and prevalence of pregnancy loss	56
Infertility treatment and offspring blood pressure—a systematic review and meta-analysis	56
Reply. How much evidence is needed to stop calling endometrial scratching ‘controversial’?	52

Endometrial scratching in women undergoing IVF/ICSI: an individual participant data meta-analysis	51
Advances in non-hormonal male contraception targeting sperm motility	50
Reply: What is the expected live birth rate per thawed oocyte?	50
Molecular insights into sperm head shaping and its role in human male fertility	48
Fertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility	48
Development and validation of a gonadotropin dose selection model for optimized ovarian stimulation in IVF/ICSI: an individual participant data meta-analysis	44
Does the holy grail of the evidence pyramid vindicate the controversial practice of endometrial scratching or is there room for healthy skepticism?	44
Moving toward totipotency: the molecular and cellular features of totipotent and naive pluripotent stem cells	43
Spermatogonia: a unique stem cell orchestrating species-specific transition from pluripotency to sperm production	42
Prevalence of polycystic ovary syndrome: a global and regional systematic review and meta-analysis	41
Harnessing omics data for drug discovery and development in ovarian aging	41