OOIR: Observatory of International Research

Papers

(The TQCC of Human Reproduction Update is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-09-01 to 2023-09-01.)

Article	Citations
Ovarian damage from chemotherapy and current approaches to its protection	239
Diagnosing adenomyosis: an integrated clinical and imaging approach	162
Sperm recovery and ICSI outcomes in men with non-obstructive azoospermia: a systematic review and meta-analysis	154
Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis	124
Endometrial function in women with polycystic ovary syndrome: a comprehensive review	120
Investigation of human trophoblast invasion in vitro	119
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) and their effects on the ovary	115
Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis	109
Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence	95
Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice	88
Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis	88
Chromosomal mosaicism in human blastocysts: the ultimate diagnostic dilemma	86
A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene–disease relationships	85
Non-invasive preimplantation genetic testing (niPGT): the next revolution in reproductive genetics?	80
Endometriosis and cancer: a systematic review and meta-analysis	79
Recurrent pregnancy loss: diagnostic workup after two or three pregnancy losses? A systematic review of the literature and meta-analysis	74
BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging	69
Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure	63
Human sperm ion channel (dys)function: implications for fertilization	58
Endometriosis recurrence following post-operative hormonal suppression: a systematic review and meta-analysis	58
Fertility preservation for transgender adolescents and young adults: a systematic review	57
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries	57
First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis	55
Mitochondria: their role in spermatozoa and in male infertility	54
In-utero stress and mode of conception: impact on regulation of imprinted genes, fetal development and future health	54

Identifying biomarkers for predicting successful embryo implantation: applying single to multi-OMICs to improve reproductive outcomes	54
Role of angiogenesis in adenomyosis-associated abnormal uterine bleeding and subfertility: a systematic review	53
Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies	51
Ovarian stimulation for freeze-all IVF cycles: a systematic review	51
Progestins for pituitary suppression during ovarian stimulation for ART: a comprehensive and systematic review including meta-analyses	49
Cancer-associated mutations in endometriosis: shedding light on the pathogenesis and pathophysiology	49
The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain	49
Immunological changes associated with adenomyosis: a systematic review	48
Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis	47
Disturbed genomic imprinting and its relevance for human reproduction: causes and clinical consequences	45
Adenomyosis pathogenesis: insights from next-generation sequencing	43
Hypothetical roadmap towards endometriosis: prenatal endocrine-disrupting chemical pollutant exposure, anogenital distance, gut-genital microbiota and subclinical infections	42
Confined placental mosaicism and the association with pregnancy outcome and fetal growth: a review of the literature	42
The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders	41
IVF and other ART in low- and middle-income countries: a systematic landscape analysis	41
Cardiometabolic health in offspring of women with PCOS compared to healthy controls: a systematic review and individual participant data meta-analysis	40
Uterine natural killer cells: from foe to friend in reproduction	39
Mild versus conventional ovarian stimulation for IVF in poor, normal and hyper-responders: a systematic review and meta-analysis	38
Do cancer therapies damage the uterus and compromise fertility?	37
Age-related presence of spermatogonia in patients with Klinefelter syndrome: a systematic review and meta-analysis	37
Haploid male germ cells—the Grand Central Station of protein transport	37
Polymorphisms and endometriosis: a systematic review and meta-analyses	36
DNA methylation in human sperm: a systematic review	35
Adipocyte and steroidogenic cell cross-talk in polycystic ovary syndrome	34
Number and function of uterine natural killer cells in recurrent miscarriage and implantation failure: a systematic review and meta-analysis	34
Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract	33
Plasticity of the human preimplantation embryo: developmental dogmas, variations on themes and self-correction	33
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction	33