OOIR: Observatory of International Research

Papers

(The TQCC of Human Reproduction Update is 43. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-07-01 to 2026-07-01.)

Article	Citations
BMI in children aged 1–18 years conceived after ART with fresh and frozen embryo transfer: a systematic review and meta-analyses	600
Building a human pluripotent stem cell-based gonadal niche: improving in vitro systems with in vivo insigh	189
The pathophysiological role of estrogens in the initial stages of pregnancy: molecular mechanisms and clinical implications for pregnancy outcome from the periconceptional period to end of the first t	153
Maternal and perinatal outcomes in twin pregnancies following assisted reproduction: a systematic review and meta-analysis involving 802 462 pregnancies	149
Iron overload disorders in adults: a comprehensive review of gonadal function, reproductive, and sexual health	125
Ultrasonographic criteria in the diagnosis of polycystic ovary syndrome: a systematic review and diagnostic meta-analysis	123
Functional hypothalamic amenorrhoea and polycystic ovarian morphology: a narrative review about an intriguing association	120
What do we mean by preconception health and preconception care in research and policy? A systematic review	118
The complicated ART of finding consensus on family-building health policy: a comment on the IFFS consensus document	114
What is the optimal GnRH antagonist protocol for ovarian stimulation during ART treatment? A systematic review and network meta-analysis	114
Total fertilization failure after ICSI: insights into pathophysiology, diagnosis, and management through artificial oocyte activation	113
Preconception lifestyle interventions for women—a systematic review and meta-analysis of intervention characteristics and behaviour change techniques	98
Driving factors in treatment decision-making of patients seeking medical assistance for infertility: a systematic review	94
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries	90
Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing	85
Sperm mitochondrial DNA copy number: a marker of male fertility and reproductive success	81
Reproductive ability in survivors of childhood, adolescent, and young adult Hodgkin lymphoma: a review	78
RNA modifications in female reproductive physiology and disease: emerging roles and clinical implications	73
Reply: Artificial cycle frozen embryo transfer and obstetric adverse outcomes: association or causation?	67
Assessing the influence of preconception diet on female fertility: a systematic scoping review of observational studies	62
Intrauterine human chorionic gonadotropin administration before embryo transfer (IHABT): an individual participant data meta-analysis of randomized controlled trials	62
What is the expected live birth rate per thawed oocyte?	61
Infertility treatment and offspring blood pressure—a systematic review and meta-analysis	59
COVID-19 in pregnant women: a systematic review and meta-analysis on the risk and prevalence of pregnancy loss	59
Reply. How much evidence is needed to stop calling endometrial scratching ‘controversial’?	56

Endometrial scratching in women undergoing IVF/ICSI: an individual participant data meta-analysis	54
Reply: What is the expected live birth rate per thawed oocyte?	54
Development and validation of a gonadotropin dose selection model for optimized ovarian stimulation in IVF/ICSI: an individual participant data meta-analysis	52
Molecular insights into sperm head shaping and its role in human male fertility	51
Fertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility	48
Advances in non-hormonal male contraception targeting sperm motility	47
Does the holy grail of the evidence pyramid vindicate the controversial practice of endometrial scratching or is there room for healthy skepticism?	45
Spermatogonia: a unique stem cell orchestrating species-specific transition from pluripotency to sperm production	45
Moving toward totipotency: the molecular and cellular features of totipotent and naive pluripotent stem cells	44
The epigenetic approach of varicocele: a focus on sperm DNA and m6A-RNA methylation	43
Prevalence of polycystic ovary syndrome: a global and regional systematic review and meta-analysis	43