Human Reproduction Update

Papers
(The median citation count of Human Reproduction Update is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
False hope for patients with Klinefelter syndrome on cryopreservation of spermatogonia at younger ages326
Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women175
Maternal and perinatal outcomes in twin pregnancies following assisted reproduction: a systematic review and meta-analysis involving 802 462 pregnancies153
The pathophysiological role of estrogens in the initial stages of pregnancy: molecular mechanisms and clinical implications for pregnancy outcome from the periconceptional period to end of the first t115
Plasticity of the human preimplantation embryo: developmental dogmas, variations on themes and self-correction113
Functional hypothalamic amenorrhoea and polycystic ovarian morphology: a narrative review about an intriguing association103
Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis89
Ultrasonographic criteria in the diagnosis of polycystic ovary syndrome: a systematic review and diagnostic meta-analysis84
Correction to: Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis83
Total fertilization failure after ICSI: insights into pathophysiology, diagnosis, and management through artificial oocyte activation80
Obstetric and neonatal outcomes of pregnancies resulting from preimplantation genetic testing: a systematic review and meta-analysis78
What is the optimal GnRH antagonist protocol for ovarian stimulation during ART treatment? A systematic review and network meta-analysis70
Should women receive luteal support following natural cycle frozen embryo transfer? A systematic review and meta-analysis. Critical assessment of a review and meta-analysis69
The complicated ART of finding consensus on family-building health policy: a comment on the IFFS consensus document67
Driving factors in treatment decision-making of patients seeking medical assistance for infertility: a systematic review66
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries63
A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene–disease relationships62
Autophagy: a multifaceted player in the fate of sperm61
Obstetric and perinatal outcomes of singleton pregnancies after blastocyst-stage embryo transfer compared with those after cleavage-stage embryo transfer: a systematic review and cumulative meta-analy60
Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing59
HLA Class Ib-receptor interactions during embryo implantation and early pregnancy57
RNA modifications in female reproductive physiology and disease: emerging roles and clinical implications56
Reproductive ability in survivors of childhood, adolescent, and young adult Hodgkin lymphoma: a review55
Prenatal and postnatal exposures to endocrine disrupting chemicals and timing of pubertal onset in girls and boys: a systematic review and meta-analysis50
Reply: Artificial cycle frozen embryo transfer and obstetric adverse outcomes: association or causation?49
The neglected members of the family: non-BRCAmutations in the Fanconi anemia/BRCA pathway and reproduction48
IVF and human evolution48
Assessing the influence of preconception diet on female fertility: a systematic scoping review of observational studies47
The missing role of diagnosis of confined placental mosaicism in the management of fetal growth restriction46
What is the expected live birth rate per thawed oocyte?45
Cell dynamics in human villous trophoblast44
Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia43
Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine42
The LH surge and ovulation re-visited: a systematic review and meta-analysis and implications for true natural cycle frozen thawed embryo transfer42
Correction to: Evaluating interventions and adjuncts to optimize pregnancy outcomes in subfertile women: an overview review42
Administration of growth hormone improves endometrial function in women undergoing in vitro fertilization: a systematic review and meta-analysis41
COVID-19 in pregnant women: a systematic review and meta-analysis on the risk and prevalence of pregnancy loss41
Infertility treatment and offspring blood pressure—a systematic review and meta-analysis39
Novel microarchitecture of human endometrial glands: implications in endometrial regeneration and pathologies38
The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain38
Reply: The missing role of diagnosis of confined placental mosaicism in the management of fetal growth restriction37
Reply. How much evidence is needed to stop calling endometrial scratching ‘controversial’?36
Reply: What is the expected live birth rate per thawed oocyte?34
Endometrial scratching in women undergoing IVF/ICSI: an individual participant data meta-analysis34
Molecular insights into sperm head shaping and its role in human male fertility33
Advances in non-hormonal male contraception targeting sperm motility32
Fertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility32
Development and validation of a gonadotropin dose selection model for optimized ovarian stimulation in IVF/ICSI: an individual participant data meta-analysis31
The epigenetic approach of varicocele: a focus on sperm DNA and m6A-RNA methylation30
DNA methylation profiles after ART during human lifespan: a systematic review and meta-analysis30
Does the holy grail of the evidence pyramid vindicate the controversial practice of endometrial scratching or is there room for healthy skepticism?30
The effects of bariatric surgery on periconception maternal health: a systematic review and meta-analysis30
Bioengineering trends in female reproduction: a systematic review30
Moving toward totipotency: the molecular and cellular features of totipotent and naive pluripotent stem cells29
Maternal germline factors associated with aneuploid pregnancy loss: a systematic review29
Harnessing omics data for drug discovery and development in ovarian aging29
DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies29
The impact of primary ciliary dyskinesia on female and male fertility: a narrative review28
Correction to: Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women28
Anti-Müllerian hormone as a marker of ovarian reserve and premature ovarian insufficiency in children and women with cancer: a systematic review28
Roles of bone morphogenetic proteins in endometrial remodeling during the human menstrual cycle and pregnancy27
Clinical application of aromatase inhibitors to treat male infertility26
Remembering Professor John Collins25
Indoor and outdoor air pollution and couple fecundability: a systematic review25
Reply. The role of endometrial scratching in IVF/ICSI: a critical appraisal of individual participant data meta-analysis21
Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities19
Prevalence of PCOS and related hyperandrogenic traits in premenopausal women with type 1 diabetes: a systematic review and meta-analysis19
From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns18
Declining global fertility rates and the implications for family planning and family building: an IFFS consensus document based on a narrative review of the literature18
Impact of Bisphenol A and its alternatives on oocyte health: a scoping review17
Reply: Should women receive luteal support following natural cycle frozen embryo transfer? A systematic review and meta-analysis. Critical assessment of a review and meta-analysis17
A systematic review to determine use of the Endometriosis Health Profiles to measure quality of life outcomes in women with endometriosis17
TGFβ signalling: a nexus between inflammation, placental health and preeclampsia throughout pregnancy17
Contribution of epididymal epithelial cell functions to sperm epigenetic changes and the health of progeny17
Anti-Müllerian hormone for the diagnosis and prediction of menopause: a systematic review16
Comparative efficacy of exercise, diet and/or pharmacological interventions on BMI, ovulation, and hormonal profile in reproductive-aged women with overweight or obesity: a systematic review and netwo16
Immunotherapies to optimize pregnancy outcomes in subfertile women15
Reply: Endometrial scratching: the light at the end of the tunnel15
Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis15
Transcriptional control of human gametogenesis15
Navigating fertility dilemmas across the lifespan in girls with Turner syndrome—a scoping review15
Epigenetic clocks provide clues to the mystery of uterine ageing14
Beyond apoptosis: evidence of other regulated cell death pathways in the ovary throughout development and life14
Evaluating interventions and adjuncts to optimize pregnancy outcomes in subfertile women: an overview review14
BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis14
Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies14
Evaluating the diagnostic accuracy of androgen measurement in polycystic ovary syndrome: a systematic review and diagnostic meta-analysis to inform evidence-based guidelines14
Planned oocyte cryopreservation: a systematic review and meta-regression analysis14
Genetic and reproductive strategies to prevent mitochondrial diseases14
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