OOIR: Observatory of International Research

Papers

(The median citation count of Human Reproduction Update is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)

Article	Citations
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries	194
Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis	188
Endometrial function in women with polycystic ovary syndrome: a comprehensive review	167
Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence	150
Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice	143
A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene–disease relationships	135
Endometriosis and cancer: a systematic review and meta-analysis	126
The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain	98
Endometriosis recurrence following post-operative hormonal suppression: a systematic review and meta-analysis	84
Mitochondria: their role in spermatozoa and in male infertility	76
Progestins for pituitary suppression during ovarian stimulation for ART: a comprehensive and systematic review including meta-analyses	75
Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies	72
Adenomyosis pathogenesis: insights from next-generation sequencing	72
Immunological changes associated with adenomyosis: a systematic review	71
Number and function of uterine natural killer cells in recurrent miscarriage and implantation failure: a systematic review and meta-analysis	69
Confined placental mosaicism and the association with pregnancy outcome and fetal growth: a review of the literature	66
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions	66
Plasticity of the human preimplantation embryo: developmental dogmas, variations on themes and self-correction	66
IVF and other ART in low- and middle-income countries: a systematic landscape analysis	64
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction	63
Uterine natural killer cells: from foe to friend in reproduction	58
Mild versus conventional ovarian stimulation for IVF in poor, normal and hyper-responders: a systematic review and meta-analysis	52
Adipocyte and steroidogenic cell cross-talk in polycystic ovary syndrome	49
All you need to know about sperm RNAs	49
Autophagy: a multifaceted player in the fate of sperm	48

Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis	48
Secretory products of the corpus luteum and preeclampsia	46
DNA methylation in human sperm: a systematic review	45
Anti-Müllerian hormone as a marker of ovarian reserve and premature ovarian insufficiency in children and women with cancer: a systematic review	45
Nanoparticles in pregnancy: the next frontier in reproductive therapeutics	45
SARS-CoV-2, fertility and assisted reproduction	44
Preconception genome medicine: current state and future perspectives to improve infertility diagnosis and reproductive and health outcomes based on individual genomic data	43
Embryo implantation in the laboratory: an update on current techniques	43
Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation	41
Current approaches and developments in transcript profiling of the human placenta	41
Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety	39
Modelling human embryogenesis: embryo-like structures spark ethical and policy debate	38
Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development	37
Morphological and morphokinetic associations with aneuploidy: a systematic review and meta-analysis	37
Lipid metabolism and endometrial receptivity	35
Bioengineering trends in female reproduction: a systematic review	35
Cell dynamics in human villous trophoblast	34
Novel therapeutic targets to improve IVF outcomes in endometriosis patients: a review and future prospects	33
Hormone therapy in the postmenopausal years: considering benefits and risks in clinical practice	33
Biomechanical forces and signals operating in the ovary during folliculogenesis and their dysregulation: implications for fertility	33
The effect of paternal exposure to immunosuppressive drugs on sexual function, reproductive hormones, fertility, pregnancy and offspring outcomes: a systematic review	32
Clinical application of aromatase inhibitors to treat male infertility	32
Obstetric and neonatal outcomes of pregnancies resulting from preimplantation genetic testing: a systematic review and meta-analysis	32
Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia	29
Is diminished ovarian reserve a risk factor for miscarriage? Results of a systematic review and meta-analysis	28
Chances of pregnancy and live birth among women undergoing conservative management of early-stage endometrial cancer: a systematic review and meta-analysis	28
Should women receive luteal support following natural cycle frozen embryo transfer? A systematic review and meta-analysis	27
Persistent organic pollutants and couple fecundability: a systematic review	27
Anti-Müllerian hormone for the diagnosis and prediction of menopause: a systematic review	27
The impact of primary ciliary dyskinesia on female and male fertility: a narrative review	26
The development of the human uterus: morphogenesis to menarche	25
Effects of different frozen embryo transfer regimens on abnormalities of fetal weight: a systematic review and meta-analysis	25
Contribution of epididymal epithelial cell functions to sperm epigenetic changes and the health of progeny	25
DNA methylation profiles after ART during human lifespan: a systematic review and meta-analysis	24
DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies	24
The putative roles of FSH and AMH in the regulation of oocyte developmental competence: from fertility prognosis to mechanisms underlying age-related subfertility	23
Contribution of semen to early embryo development: fertilization and beyond	23
Novel microarchitecture of human endometrial glands: implications in endometrial regeneration and pathologies	23
Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine	23
Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing	22
The effects of bariatric surgery on periconception maternal health: a systematic review and meta-analysis	22
Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women	21
Obstetric and perinatal outcomes of singleton pregnancies after blastocyst-stage embryo transfer compared with those after cleavage-stage embryo transfer: a systematic review and cumulative meta-analy	21
The LH surge and ovulation re-visited: a systematic review and meta-analysis and implications for true natural cycle frozen thawed embryo transfer	21
Outcomes of pregnancies using donor sperm compared with those using partner sperm: systematic review and meta-analysis	21
A review on the motivations, decision-making factors, attitudes and experiences of couples using pre-implantation genetic testing for inherited conditions	20
Offspring physiology following the use of IVM, IVF and ICSI: a systematic review and meta-analysis of animal studies	20
Stanniocalcin-1 in the female reproductive system and pregnancy	20
Beyond apoptosis: evidence of other regulated cell death pathways in the ovary throughout development and life	20
The other face of advanced paternal age: a scoping review of its terminological, social, public health, psychological, ethical and regulatory aspects	20

HLA Class Ib-receptor interactions during embryo implantation and early pregnancy	19
Ovarian stimulation for oocyte donation: a systematic review and meta-analysis	19
Epigenomic and enhancer dysregulation in uterine leiomyomas	19
Endometrial receptivity in women of advanced age: an underrated factor in infertility	18
Interventions to optimize embryo transfer in women undergoing assisted conception: a comprehensive systematic review and meta-analyses	18
Risk of foetal harm with letrozole use in fertility treatment: a systematic review and meta-analysis	18
Impacts of platinum-based chemotherapy on subsequent testicular function and fertility in boys with cancer	18
New era of trophoblast research: integrating morphological and molecular approaches	18
Reproductive ability in survivors of childhood, adolescent, and young adult Hodgkin lymphoma: a review	17
Is there an association between paternal age and aneuploidy? Evidence from young donor oocyte-derived embryos: a systematic review and individual patient data meta-analysis	16
Does hormonal therapy improve sperm retrieval rates in men with non-obstructive azoospermia: a systematic review and meta-analysis	16
Maternal germline factors associated with aneuploid pregnancy loss: a systematic review	16
Prenatal and postnatal exposures to endocrine disrupting chemicals and timing of pubertal onset in girls and boys: a systematic review and meta-analysis	16
BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis	16
Immediate versus postponed frozen embryo transfer after IVF/ICSI: a systematic review and meta-analysis	15
Efficacy of psychological interventions for mental health and pregnancy rates among individuals with infertility: a systematic review and meta-analysis	15
Defensins: defenders of human reproductive health	15
Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis	15
Will Single-Cell RNAseq decipher stem cells biology in normal and cancerous tissues?	14
Neurophysiology of cognitive behavioural therapy, deep breathing and progressive muscle relaxation used in conjunction with ART treatments: a narrative review	14
Prevalence of PCOS and related hyperandrogenic traits in premenopausal women with type 1 diabetes: a systematic review and meta-analysis	14
Obstetric and neonatal outcomes after natural versus artificial cycle frozen embryo transfer and the role of luteal phase support: a systematic review and meta-analysis	14
Uterus transplantation: from research, through human trials and into the future	14
The multiple roles of RAB GTPases in female and male meiosis	14
Administration of growth hormone improves endometrial function in women undergoing in vitro fertilization: a systematic review and meta-analysis	14