OOIR: Observatory of International Research

Papers

(The median citation count of Human Reproduction Update is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries	229
Endometrial function in women with polycystic ovary syndrome: a comprehensive review	182
Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence	167
Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice	155
A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene–disease relationships	151
Endometriosis and cancer: a systematic review and meta-analysis	140
The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain	110
Endometriosis recurrence following post-operative hormonal suppression: a systematic review and meta-analysis	92
Adenomyosis pathogenesis: insights from next-generation sequencing	84
Mitochondria: their role in spermatozoa and in male infertility	80
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions	76
Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies	75
Immunological changes associated with adenomyosis: a systematic review	75
Plasticity of the human preimplantation embryo: developmental dogmas, variations on themes and self-correction	74
Number and function of uterine natural killer cells in recurrent miscarriage and implantation failure: a systematic review and meta-analysis	71
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction	70
Confined placental mosaicism and the association with pregnancy outcome and fetal growth: a review of the literature	69
IVF and other ART in low- and middle-income countries: a systematic landscape analysis	67
Uterine natural killer cells: from foe to friend in reproduction	64
Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis	59
All you need to know about sperm RNAs	56
Adipocyte and steroidogenic cell cross-talk in polycystic ovary syndrome	54
Autophagy: a multifaceted player in the fate of sperm	53
Mild versus conventional ovarian stimulation for IVF in poor, normal and hyper-responders: a systematic review and meta-analysis	52
SARS-CoV-2, fertility and assisted reproduction	51

Anti-Müllerian hormone as a marker of ovarian reserve and premature ovarian insufficiency in children and women with cancer: a systematic review	49
Nanoparticles in pregnancy: the next frontier in reproductive therapeutics	49
Secretory products of the corpus luteum and preeclampsia	49
Embryo implantation in the laboratory: an update on current techniques	48
Preconception genome medicine: current state and future perspectives to improve infertility diagnosis and reproductive and health outcomes based on individual genomic data	46
Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development	45
Morphological and morphokinetic associations with aneuploidy: a systematic review and meta-analysis	45
Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation	43
Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety	43
Current approaches and developments in transcript profiling of the human placenta	42
Bioengineering trends in female reproduction: a systematic review	39
Clinical application of aromatase inhibitors to treat male infertility	39
Lipid metabolism and endometrial receptivity	38
Cell dynamics in human villous trophoblast	38
Biomechanical forces and signals operating in the ovary during folliculogenesis and their dysregulation: implications for fertility	36
Hormone therapy in the postmenopausal years: considering benefits and risks in clinical practice	36
Obstetric and neonatal outcomes of pregnancies resulting from preimplantation genetic testing: a systematic review and meta-analysis	35
Novel therapeutic targets to improve IVF outcomes in endometriosis patients: a review and future prospects	35
Anti-Müllerian hormone for the diagnosis and prediction of menopause: a systematic review	34
Contribution of semen to early embryo development: fertilization and beyond	33
Beyond apoptosis: evidence of other regulated cell death pathways in the ovary throughout development and life	31
The putative roles of FSH and AMH in the regulation of oocyte developmental competence: from fertility prognosis to mechanisms underlying age-related subfertility	31
Chances of pregnancy and live birth among women undergoing conservative management of early-stage endometrial cancer: a systematic review and meta-analysis	30
Should women receive luteal support following natural cycle frozen embryo transfer? A systematic review and meta-analysis	30
The impact of primary ciliary dyskinesia on female and male fertility: a narrative review	29
Is diminished ovarian reserve a risk factor for miscarriage? Results of a systematic review and meta-analysis	29
Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine	29
Persistent organic pollutants and couple fecundability: a systematic review	29
DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies	29
Contribution of epididymal epithelial cell functions to sperm epigenetic changes and the health of progeny	28
The development of the human uterus: morphogenesis to menarche	28
Obstetric and perinatal outcomes of singleton pregnancies after blastocyst-stage embryo transfer compared with those after cleavage-stage embryo transfer: a systematic review and cumulative meta-analy	26
DNA methylation profiles after ART during human lifespan: a systematic review and meta-analysis	26
Effects of different frozen embryo transfer regimens on abnormalities of fetal weight: a systematic review and meta-analysis	26
Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing	26
The LH surge and ovulation re-visited: a systematic review and meta-analysis and implications for true natural cycle frozen thawed embryo transfer	25
A review on the motivations, decision-making factors, attitudes and experiences of couples using pre-implantation genetic testing for inherited conditions	25
Novel microarchitecture of human endometrial glands: implications in endometrial regeneration and pathologies	25
Interventions to optimize embryo transfer in women undergoing assisted conception: a comprehensive systematic review and meta-analyses	24
Risk of foetal harm with letrozole use in fertility treatment: a systematic review and meta-analysis	24
The effects of bariatric surgery on periconception maternal health: a systematic review and meta-analysis	24
The other face of advanced paternal age: a scoping review of its terminological, social, public health, psychological, ethical and regulatory aspects	24
Stanniocalcin-1 in the female reproductive system and pregnancy	24
Offspring physiology following the use of IVM, IVF and ICSI: a systematic review and meta-analysis of animal studies	24
Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women	23
Epigenomic and enhancer dysregulation in uterine leiomyomas	23
Endometrial receptivity in women of advanced age: an underrated factor in infertility	23
Uterus transplantation: from research, through human trials and into the future	23
HLA Class Ib-receptor interactions during embryo implantation and early pregnancy	22
BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis	22

Outcomes of pregnancies using donor sperm compared with those using partner sperm: systematic review and meta-analysis	21
Obstetric and neonatal outcomes after natural versus artificial cycle frozen embryo transfer and the role of luteal phase support: a systematic review and meta-analysis	21
Defensins: defenders of human reproductive health	21
Does hormonal therapy improve sperm retrieval rates in men with non-obstructive azoospermia: a systematic review and meta-analysis	20
Reproductive ability in survivors of childhood, adolescent, and young adult Hodgkin lymphoma: a review	20
Ovarian stimulation for oocyte donation: a systematic review and meta-analysis	20
Efficacy of psychological interventions for mental health and pregnancy rates among individuals with infertility: a systematic review and meta-analysis	19
Neurophysiology of cognitive behavioural therapy, deep breathing and progressive muscle relaxation used in conjunction with ART treatments: a narrative review	18
Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis	18
Prenatal and postnatal exposures to endocrine disrupting chemicals and timing of pubertal onset in girls and boys: a systematic review and meta-analysis	18
Maternal germline factors associated with aneuploid pregnancy loss: a systematic review	17
The pathophysiological role of estrogens in the initial stages of pregnancy: molecular mechanisms and clinical implications for pregnancy outcome from the periconceptional period to end of the first t	17
Is there an association between paternal age and aneuploidy? Evidence from young donor oocyte-derived embryos: a systematic review and individual patient data meta-analysis	17
Administration of growth hormone improves endometrial function in women undergoing in vitro fertilization: a systematic review and meta-analysis	16
Immediate versus postponed frozen embryo transfer after IVF/ICSI: a systematic review and meta-analysis	15
Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities	15
Evaluating interventions and adjuncts to optimize pregnancy outcomes in subfertile women: an overview review	15
Declining global fertility rates and the implications for family planning and family building: an IFFS consensus document based on a narrative review of the literature	15
Recovery of menses after functional hypothalamic amenorrhoea: if, when and why	15