Human Reproduction Update

(The median citation count of Human Reproduction Update is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis176
Investigation of human trophoblast invasion in vitro150
Endometrial function in women with polycystic ovary syndrome: a comprehensive review150
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries148
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) and their effects on the ovary147
Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence134
Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis130
Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice122
Endometriosis and cancer: a systematic review and meta-analysis115
A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene–disease relationships113
The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain82
Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure78
Progestins for pituitary suppression during ovarian stimulation for ART: a comprehensive and systematic review including meta-analyses72
Endometriosis recurrence following post-operative hormonal suppression: a systematic review and meta-analysis71
Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies68
Mitochondria: their role in spermatozoa and in male infertility68
Adenomyosis pathogenesis: insights from next-generation sequencing62
Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis61
Immunological changes associated with adenomyosis: a systematic review59
Number and function of uterine natural killer cells in recurrent miscarriage and implantation failure: a systematic review and meta-analysis58
IVF and other ART in low- and middle-income countries: a systematic landscape analysis57
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction55
Confined placental mosaicism and the association with pregnancy outcome and fetal growth: a review of the literature54
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions51
Uterine natural killer cells: from foe to friend in reproduction51
The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders51
Plasticity of the human preimplantation embryo: developmental dogmas, variations on themes and self-correction51
Haploid male germ cells—the Grand Central Station of protein transport48
Adipocyte and steroidogenic cell cross-talk in polycystic ovary syndrome47
Mild versus conventional ovarian stimulation for IVF in poor, normal and hyper-responders: a systematic review and meta-analysis46
DNA methylation in human sperm: a systematic review43
Secretory products of the corpus luteum and preeclampsia41
Preconception genome medicine: current state and future perspectives to improve infertility diagnosis and reproductive and health outcomes based on individual genomic data41
Current approaches and developments in transcript profiling of the human placenta40
Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis40
Anti-Müllerian hormone as a marker of ovarian reserve and premature ovarian insufficiency in children and women with cancer: a systematic review40
Nanoparticles in pregnancy: the next frontier in reproductive therapeutics40
Embryo implantation in the laboratory: an update on current techniques40
Autophagy: a multifaceted player in the fate of sperm39
All you need to know about sperm RNAs39
Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation38
Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract38
Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety34
Modelling human embryogenesis: embryo-like structures spark ethical and policy debate34
The dawn of the future: 30 years from the first biopsy of a human embryo. The detailed history of an ongoing revolution34
Does an association exist between menstrual cycle length within the normal range and ovarian reserve biomarkers during the reproductive years? A systematic review and meta-analysis33
SARS-CoV-2, fertility and assisted reproduction32
The effect of paternal exposure to immunosuppressive drugs on sexual function, reproductive hormones, fertility, pregnancy and offspring outcomes: a systematic review31
Studying human reproductive biology through single-cell analysis and in vitro differentiation of stem cells into germ cell-like cells31
Cell dynamics in human villous trophoblast31
Obstetric and neonatal outcomes of pregnancies resulting from preimplantation genetic testing: a systematic review and meta-analysis31
Novel therapeutic targets to improve IVF outcomes in endometriosis patients: a review and future prospects29
Bioengineering trends in female reproduction: a systematic review28
Morphological and morphokinetic associations with aneuploidy: a systematic review and meta-analysis28
Hormone therapy in the postmenopausal years: considering benefits and risks in clinical practice27
Chances of pregnancy and live birth among women undergoing conservative management of early-stage endometrial cancer: a systematic review and meta-analysis27
Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia27
Lipid metabolism and endometrial receptivity26
Clinical application of aromatase inhibitors to treat male infertility26
Is diminished ovarian reserve a risk factor for miscarriage? Results of a systematic review and meta-analysis26
Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development26
Persistent organic pollutants and couple fecundability: a systematic review25
Should women receive luteal support following natural cycle frozen embryo transfer? A systematic review and meta-analysis25
Sperm retrieval rates by micro-TESE versus conventional TESE in men with non-obstructive azoospermia—the assumption of independence in effect sizes might lead to misleading conclusions25
The development of the human uterus: morphogenesis to menarche23
Contribution of epididymal epithelial cell functions to sperm epigenetic changes and the health of progeny23
DNA methylation profiles after ART during human lifespan: a systematic review and meta-analysis23
Effects of different frozen embryo transfer regimens on abnormalities of fetal weight: a systematic review and meta-analysis22
Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine21
Outcomes of pregnancies using donor sperm compared with those using partner sperm: systematic review and meta-analysis20
The effects of bariatric surgery on periconception maternal health: a systematic review and meta-analysis20
The putative roles of FSH and AMH in the regulation of oocyte developmental competence: from fertility prognosis to mechanisms underlying age-related subfertility20
The functions of CAP superfamily proteins in mammalian fertility and disease20
Obstetric and perinatal outcomes of singleton pregnancies after blastocyst-stage embryo transfer compared with those after cleavage-stage embryo transfer: a systematic review and cumulative meta-analy19
Biomechanical forces and signals operating in the ovary during folliculogenesis and their dysregulation: implications for fertility19
A review on the motivations, decision-making factors, attitudes and experiences of couples using pre-implantation genetic testing for inherited conditions18
Anti-Müllerian hormone for the diagnosis and prediction of menopause: a systematic review18
Novel microarchitecture of human endometrial glands: implications in endometrial regeneration and pathologies17
New era of trophoblast research: integrating morphological and molecular approaches17
HLA Class Ib-receptor interactions during embryo implantation and early pregnancy17
Risk of foetal harm with letrozole use in fertility treatment: a systematic review and meta-analysis17
The other face of advanced paternal age: a scoping review of its terminological, social, public health, psychological, ethical and regulatory aspects17
Ovarian stimulation for oocyte donation: a systematic review and meta-analysis17
Impacts of platinum-based chemotherapy on subsequent testicular function and fertility in boys with cancer16
Stanniocalcin-1 in the female reproductive system and pregnancy16
C-reactive protein and ART outcomes: a systematic review16
Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing16
DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies16
Is there an association between paternal age and aneuploidy? Evidence from young donor oocyte-derived embryos: a systematic review and individual patient data meta-analysis15
Epigenomic and enhancer dysregulation in uterine leiomyomas15
The impact of primary ciliary dyskinesia on female and male fertility: a narrative review15
Maternal germline factors associated with aneuploid pregnancy loss: a systematic review15
Will Single-Cell RNAseq decipher stem cells biology in normal and cancerous tissues?14
The LH surge and ovulation re-visited: a systematic review and meta-analysis and implications for true natural cycle frozen thawed embryo transfer14
Beyond apoptosis: evidence of other regulated cell death pathways in the ovary throughout development and life14
Immediate versus postponed frozen embryo transfer after IVF/ICSI: a systematic review and meta-analysis13
Neurophysiology of cognitive behavioural therapy, deep breathing and progressive muscle relaxation used in conjunction with ART treatments: a narrative review13
Prevalence of PCOS and related hyperandrogenic traits in premenopausal women with type 1 diabetes: a systematic review and meta-analysis13
Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women13