OOIR: Observatory of International Research

Papers

(The TQCC of Biomarkers is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Conjunctival microbiome changes in soft contact lens users and contact lens discomfort patients	31
Dexmedetomidine modulates mitochondrial dynamics to protect against endotoxin-induced lung injury via the protein kinase C-ɑ/haem oxygenase-1 signalling pathway	29
Cardiac extracellular matrix modulation in a rat-diabetic model: biochemical and anti-oxidant beneficial effect of pomegranate (Punica granatum) peel extract	26
Association of cardiac biomarkers with long-term cardiovascular events in a community cohort	24
A review ongarcinia kolaheckel: traditional uses, phytochemistry, pharmacological activities, and toxicology	23
Neuroprotective effects of magnesium against stress induced by hydrogen peroxide in Wistar rat	22
Nucleosome assembly protein 1-like 1 (NAP1L1) in gastric cancer patients: a potential biomarker with diagnostic and prognostic utility	20
Serum prealbumin level as a biomarker of survival outcomes in patients with gastric cancer: a meta-analysis	20
CYP450 gene polymorphisms and the risk of taxane-induced neurotoxicity in breast cancer patients: a systematic review and meta-analysis	18
Serum ferritin can serve as a biomarker for the prognosis and increased the prognostic predictive value of ISS/RISS in multiple myeloma patients	16
Assessment of biomarkers of exposure and potential harm, and physiological and subjective health measures in exclusive users of nicotine pouches and current, former and never smokers	15
Free lung desmosine: a potential biomarker for elastic fiber injury in pulmonary emphysema	15
Anti-diabetogenic and in vivo antioxidant activity of ethanol extract of Dryopteris dilatata in alloxan-induced male Wistar rats	14
δ_EPCD: the electrophysiologic coefficient of depressiveness	14
Commentary: statistical analysis of 2 × 2 tables in biomarker studies 3) design, interpretation and guidelines	14
Insight into the role of myokines and myogenic regulatory factors under hypobaric hypoxia induced skeletal muscle loss	13
Alloimperatorin from Ammi majus fruits mitigates Piroxicam-provoked gastric ulcer and hepatorenal toxicity in ratsviasuppressing oxidative stress and apoptosis	13
The predictive role of early CRP values for one-year mortality in the first 2 d after acute myocardial infarction	12
Determination of biomarkers of chlorine exposure from biological samples: a review of analysis techniques	12
Investigation of exosomal tetraspanin profile in sepsis patients as a promising diagnostic biomarker	12
The prognostic utility of galectin-3 in patients undergoing cardiac surgery: a scoping review	12
Commentary: statistical analysis of 2 × 2 tables in biomarker studies 2) study design and statistical tests	12
Hyponatremia in the emergency department: an overview of diagnostic and therapeutic approach	12
The role of pentraxin 3 and cathepsin B levels in pregnancies complicated by preeclampsia	12
Urinary anatalline and nicotelline cut-points to distinguish between exclusive and dual use of tobacco products	11

Evaluation of the role of human neutrophil elastase, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio as predictive markers for severity of acute respiratory toxicity among patients admitted	11
Validation of host cerebrospinal fluid protein biomarkers for early diagnosis of tuberculous meningitis in children: a replication and new biosignature discovery study	11
Programmed death-ligand 1 (PD-L1) expression predicts response to neoadjuvant chemotherapy in triple-negative breast cancer: a systematic review and meta-analysis	11
Pre-treatment systemic immune-inflammation index as a non-invasive biomarker for predicting clinical outcomes in patients with renal cell carcinoma: a meta-analysis of 20 studies	11
Serum and sputum MMP-9/TIMP-1 in winter sports athletes and swimmers: relationships with airway function	11
The significance of CD14 in clear cell renal cell carcinoma progression and survival prognosis	10
Dynamine 3 as a diagnostic and prognostic biomarker in pancreatic cancer: Implications for early detection and targeted therapy	9
Screening of radiation gastrointestinal injury biomarkers in rat plasma by high-coverage targeted lipidomics	9
Investigation of glial fibrillary acidic protein (GFAP) in body fluids as a potential biomarker for glioma: a systematic review and meta-analysis	9
The vasculogenic mimicry, CD146 ⁺ and CD105 ⁺ microvessel density in the prognosis of endometrioid endometrial adenocarcinoma: a s	9
A future blood test for acute traumatic spinal cord injury	9
Perspectives on cardiovascular biomarkers: one fits all biomarkers are out, personalization is in	9
High circulating microRNA-197 levels are associated with an increased risk of incident stroke among elderly survivors of the Great East Japan Earthquake	8
Acute titanium dioxide nanoparticles exposure impaired spatial cognitive performance through neurotoxic and oxidative mechanisms in Wistar rats	8
Topical and oral applications of Aloe vera improve healing of deep second-degree burns in rats via modulation of growth factors	8
Cystatin C and mortality risk in the general population: systematic review and dose response meta-analysis	8
ERH is a prognostic biomarker associated with immune cell infiltration in lung cancer	8
Expression levels of ACE and ACE2 in the placenta and white adipose tissue of lean and obese pregnant women	7
The association between systemic inflammation markers and the risk of incident dilated cardiomyopathy: a prospective study of 351,148 participants	7
Analytical factors and interpretative issues in red blood cell distribution width and their impact on the atrial fibrillation literature	7
MicroRNA profile as potential molecular signature for attention deficit hyperactivity disorder in children	7
Prognostic value of pre-treatment advanced lung cancer inflammation index in non-small cell lung cancer: a meta-analysis	7
Arginase is upregulated in healthy women infected by oncogenic HPV types	7
CD105-microvessel density analysis and its clinical value in urothelial carcinoma of bladder patients	7
Protective effect of thymoquinone in preventing trauma-related damage: an experimental study	7
Localization and characterization of proenkephalin-A as a potential biomarker for kidney disease in murine and human kidneys	7
Phytochemical constituents and protective efficacy ofSchefflera arboricolaL. leaves extract against thioacetamide-induced hepatic encephalopathy in rats	6
Polymorphisms in ERCC1, ERCC4 and ERCC5 genes as biomarkers of susceptibility for pesticide-induced DNA damage in North-West Indian agricu	6
Clinical significance of Talin-1 and HER-2 status in different types of gastric carcinoma	6
Evaluation of the role of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and mean platelet volume (MPV) time series as predictors of diagnosis and prognosis of hemotoxic snak	6
Persistently elevated levels of sST2 after acute coronary syndrome are associated with recurrent cardiac events	6
Downregulation of IRAIN long non-coding RNA predicts unfavourable clinical outcome in acute myeloid leukaemia patients	6
The role of maternal serum ischemia-modified albumin in the prediction of hyperemesis gravidarum: a prospective cohort study	6
Abstracts for the 17 ^th Annual Biomarkers and Personalized Medicine in Cardiovascular Disease Symposium	6
Usability of presepsin, calprotectin, and interleukin 6 in the diagnosis of acute appendicitis	6
Utilizing circulating tumour DNA as a prognostic predictor of gastric cancer: a meta-analysis	6
Probiotics as a targeted intervention in anti-ageing: a review	6
Serum neurofilament light chain in functionally relevant coronary artery disease and adverse cardiovascular outcomes	6
Evaluating cell-free circulatory mitochondrial DNA as a comprehensive biomarker for stress: meta-analysis of psychological and physiological stress responses	6
Exploring the potential of humanin as a biomarker for early breast cancer detection: a study of serum levels and diagnostic performance	6
Bromuconazole fungicide induces cell cycle arrest and apoptotic cell death in cultured human colon carcinoma cells (HCT116) via oxidative stress process	6
Aluminium, lead and manganese mixture exacerbates oxidative stress, neuroinflammation and apoptosis via downregulation of Nrf-2/HO-1/BDNF signalling pathway in rats	6
Apoptotic and anti-angiogenic effects of propolis against human bladder cancer: molecular docking and in vitro screening	6
Identification of ion channel-related genes as diagnostic markers and potential therapeutic targets for osteoarthritis through bioinformatics and machine learning-based approaches	5
Circulating microRNA-27a and -133a are negatively associated with incident hypertension: a five-year longitudinal population-based study	5
A systematic review of first-trimester blood biomarkers associated with preterm prelabor rupture of the fetal membranes	5
Cancer stem cells (CSCs): key player of radiotherapy resistance and its clinical significance	5
Study on the daily Ad Libitum smoking habits of active Korean smokers and their effect on urinary smoking exposure and impact biomarkers	5
Predictors of long-term all-cause mortality after carotid artery stenting: evaluation of the Naples prognostic score	5
The ischaemia-modified albumin test: new tricks for an old dog?	5

Risk factors for Staphylococcus aureus colonization in a general emergency department patient cohort – results of an observational cohort study	5
The diagnostic value of serum YKL-40 in endometrial cancer: a meta-analysis	5
Role of procalcitonin, C-reactive protein and ferritin in cytokine release syndrome after CAR T-cell therapy in children and young adults	5
Commentary: statistical analysis of 2 × 2 tables in biomarker studies 1) the four ‘indices of test validity’	5
A prognostic risk model based on lactate metabolism and transport-related lncRNAs for gastric adenocarcinoma	5
Importance of mannose-binding lectin2 polymorphism (rs1800450) in infections in children	5
Potential biomarkers in endometrial cancer: a narrative review	5
Exosomal therapy mitigates silver nanoparticles-induced neurotoxicity in rats	5
Serum biomarkers for monitoring response to tuberculosis treatment: an assessment of the effect of different covariates among slow and fast treatment responders	5