OOIR: Observatory of International Research

Papers

(The median citation count of Biomarkers is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Assessment of serum ferritin as a biomarker in COVID-19: bystander or participant? Insights by comparison with other infectious and non-infectious diseases	77
SARS-CoV-2 antigen rapid immunoassay for diagnosis of COVID-19 in the emergency department	66
The receptor for advanced glycation end product (RAGE) pathway in COVID-19	40
Toxicity and biomarkers of micro-plastic in aquatic environment: a review	31
Biomarkers and short-term prognosis in COVID-19	30
Association between cardiac troponin I and mortality in patients with COVID-19	29
Mass mortality in endangered fan musselsPinna nobilis(Linnaeus 1758) caused by co-infection ofHaplosporidium pinnaeand multipleVibrioinfection in Çanakkale Strait, Turkey	28
Polyamine biomarkers as indicators of human disease	26
Serum anion gap at admission predicts all-cause mortality in critically ill patients with cerebral infarction: evidence from the MIMIC-III database	23
High sensitivity Troponin-T for prediction of adverse events in patients with COVID-19	22
Elevated serum ferritin level effectively discriminates severity illness and liver injury of coronavirus disease 2019 pneumonia	21
Environmental biomonitoring by snails	21
A review ongarcinia kolaheckel: traditional uses, phytochemistry, pharmacological activities, and toxicology	21
Cancer stem cells (CSCs): key player of radiotherapy resistance and its clinical significance	20
Gestational diabetes mellitus and inflammatory biomarkers of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio: a systematic review and meta-analysis	18
Insights of rheumatoid arthritis biomarkers	18
Cabbage juice protect against lead-induced liver and kidney damage in male Wistar rat	17
Circulating miR-21 as a potential biomarker in human digestive system carcinoma: a systematic review and diagnostic meta-analysis	17
Role of exosomes and its emerging therapeutic applications in the pathophysiology of non-infectious diseases	16
In vitro evaluation of Annona muricata L. (Soursop) leaf methanol extracts on inhibition of tumorigenicity and metastasis of breast cancer cells	14
Investigation of glial fibrillary acidic protein (GFAP) in body fluids as a potential biomarker for glioma: a systematic review and meta-analysis	13
Comparison of clinical usefulness of serum Ca125 and CA19-9 in pancreatic adenocarcinoma diagnosis: meta-analysis and systematic review of literature	13
MR-proAdrenomedullin as a predictor of renal replacement therapy in a cohort of critically ill patients with COVID-19	13
Apoptotic and anti-angiogenic effects of propolis against human bladder cancer: molecular docking and in vitro screening	13
miR-455-3p alleviates propofol-induced neurotoxicity by reducing EphA4 expression in developing neurons	12

Effects of cinnamaldehyde on glucose-6-phosphate dehydrogenase activity, some biochemical and hematological parameters in diabetic rats	12
Gastro-protective effect ofArtemisia Sieberiessential oil against ethanol-induced ulcer in rats as revealed via biochemical, histopathological and metabolomics analysis	12
Quercetin ameliorates the hepatic apoptosis of foetal rats induced by in utero exposure to fenitrothion via the transcriptional regulation of paraoxonase-1 and apoptosis-related genes	11
Toxicity of gamma aluminium oxide nanoparticles in the Mediterranean mussel (Mytilus galloprovincialis): histopathological alterations and antioxidant responses in the gill and digestive gland	11
Exposure to variable doses of nickel oxide nanoparticles disturbs serum biochemical parameters and oxidative stress biomarkers from vital organs of albino mice in a sex-specific manner	11
Copeptin combined with either non-high sensitivity or high sensitivity cardiac troponin for instant rule-out of suspected non-ST segment elevation myocardial infarction	11
CircRNA CDR1as: a novel diagnostic and prognostic biomarker for gastric cancer	10
Isolation and characterization of flavonoid compounds fromStachytarpheta jamaicensis(L.) Vahl and its role as anti-gastro ulcerative agent in rats	10
Photobiomodulation modulates inflammation and oral microbiome: a pilot study	10
Exposure to pesticides and oxidative stress in Brazilian agricultural communities	10
Diagnostic value of lncRNA HOTAIR as a biomarker for detecting and staging of non-small cell lung cancer	10
The first evidence of microplastic uptake in natural freshwater mussel,Unio stevenianusfrom Karasu River, Turkey	10
Integrated analysis of mRNA–m⁶A–protein profiles reveals novel insights into the mechanisms for cadmium-induced urothelial transformation	9
Chronic exposure to ethanol alters the expression of miR-155, miR-122 and miR-217 in alcoholic liver disease in an adult zebrafish model	9
A biomarker based severity progression indicator for COVID-19: the Kuwait prognosis indicator score	9
Neuroprotective role of medicinal plant extracts evaluated in a scopolamine-induced rat model of Alzheimer's disease	9
Protective effect of rutin and β-cyclodextrin against hepatotoxicity and nephrotoxicity induced by lambda-cyhalothrin in Wistar rats: biochemical, pathological indices and molecular analysis	9
Readily available biomarkers predict poor survival in metastatic pancreatic cancer	9
Bioactive compounds and therapeutic role ofBrassica oleraceaL. seeds in rheumatoid arthritis ratsviaregulating inflammatory signalling pathways and antagonizing interleukin-1 receptor ac	9
Urine soluble urokinase plasminogen activator receptor as a potential biomarker of lupus nephritis activity	9
Exosomal miRNAs and breast cancer: a complex theranostics interlink with clinical significance	9
Automatic text-mining as an unbiased approach to uncover molecular associations between periodontitis and coronary artery disease	9
Antioxidant system biomarkers of freshwater mussel (Unio tigridis) respond to nanoparticle (Al₂O₃, CuO, TiO₂) exposures	8
Chemical compositions of Commiphora opobalsamum stem bark to alleviate liver complications in streptozotocin-induced diabetes in rats: Role of oxidative stress and DNA damage	8
Serum anti-Müllerian hormone levels are associated with low bone mineral density in premenopausal women	8
Assessment of biomarkers of exposure and potential harm, and physiological and subjective health measures in exclusive users of nicotine pouches and current, former and never smokers	8
Pulicaria crispamitigates nephrotoxicity induced by carbon tetrachloride in ratsviaregulation oxidative, inflammatory, tubular and glomerular indices	8
Exposure to 1,3-Butadiene in the U.S. Population: National Health and Nutrition Examination Survey 2011–2016	8
Sex-specific cut-off values for soluble suppression of tumorigenicity 2 (ST2) biomarker increase its cardiovascular prognostic value in the community	8
Au-TiO₂nanoparticles exposure induced oxidative stress and neurotoxicity in rat	8
Metabolomics approach ofSymphyotrichum squamatumethanol extract and its nano-Ag formulation protective effect on gastric ulcerviabio-chemical and pathological analyses	8
Vitamin C and E supplementation can ameliorate NaF mediated testicular and spermatozoal DNA damages in adult Wistar rats	8
MeCP2 attenuates cardiomyocyte hypoxia/reperfusion-induced injury via regulation of the SFRP4/Wnt/β-catenin axis	8
Role of biomarkers CA-125, CA-15.3 and CA-19.9 in the distinction between endometriomas and ovarian neoplasms	8
Evaluation of serum concentrations of hs-CRP and Hb in varying severities of chronic periodontitis	8
Diagnostic and prognostic value of secreted phosphoprotein 1 for idiopathic pulmonary fibrosis: a systematic review and meta-analysis	8
Programmed death-ligand 1 (PD-L1) expression predicts response to neoadjuvant chemotherapy in triple-negative breast cancer: a systematic review and meta-analysis	7
Dopaminergic and glutamatergic biomarkers disruption in addiction and regulation by exercise: a mini review	7
Blood eosinophils as predictor of outcomes in patients hospitalized for COPD exacerbations: a prospective observational study	7
Asymmetric dimethylarginine level as biomarkers of cardiovascular or all-cause mortality in patients with chronic kidney disease: a meta-analysis	7
Salvia hispanica L.seeds extract alleviate encephalopathy in streptozotocin-induced diabetes in rats: role of oxidative stress, neurotransmitters, DNA and histological indices	7
Extracellular vesicles released in blood of COVID-19 patients: mechanism for detection of cardiac troponin after myocardial injury?	7
The diagnostic and clinicopathological value of trefoil factor 3 in patients with gastric cancer: a systematic review and meta-analysis	7
Acute titanium dioxide nanoparticles exposure impaired spatial cognitive performance through neurotoxic and oxidative mechanisms in Wistar rats	6
Antioxidant responses and lipid peroxidation can be used as sensitive indicators for the heavy metals risk assessment of the Wei River: a case study of planarian Dugesia Japonica	6
Anti-diabetogenic and in vivo antioxidant activity of ethanol extract of Dryopteris dilatata in alloxan-induced male Wistar rats	6
MicroRNA profile as potential molecular signature for attention deficit hyperactivity disorder in children	6
Downregulation of fibrosis and inflammatory signalling pathways in rats liverviaPulicaria crispaaerial parts ethanol extract	6
Bicuspid aortopathy – molecular involvement of microRNAs and MMP-TIMP	6
Lower vitamin D levels and VDR FokI variants are associated with susceptibility to sepsis: a hospital-based case-control study	6

NCR3LG1 (B7-H6) is a potential prognostic factor for bladder cancer patients	6
The impact of mitochondria-related POLG and TFAM variants on breast cancer pathomorphological characteristics and patient outcomes	6
Predicting fracture healing with blood biomarkers: the potential to assess patient risk of fracture nonunion	6
Association of CTLA-4 gene polymorphisms and alopecia areata: a systematic review and meta-analysis	6
Plukenetia conophora seed oil ameliorates streptozotocin-induced hyperglycaemia and oxidative stress in rats	6
Fibroblast growth factor-23 as a biomarker of adverse outcomes in patients with coronary artery disease: a meta-analysis	5
The level of S-glutathionylated protein is a predictor for metastasis in colorectal cancer and correlated with those of Nrf2/Keap1 pathway	5
Cissus quadrangularis extract mitigates diabetic cardiomyopathy by inhibiting RAAS activation, inflammation and oxidative stress	5
Alloimperatorin from Ammi majus fruits mitigates Piroxicam-provoked gastric ulcer and hepatorenal toxicity in ratsviasuppressing oxidative stress and apoptosis	5
One fits all hs troponin or more personalized dual markers strategies in the primary diagnostic assessment of patients with suspected acute coronary syndrome?	5
Can serum resistin predict severity of acute pancreatitis?	5
Diagnostic accuracy and prognostic significance of osteopontin in liver cirrhosis and hepatocellular carcinoma: a Meta-analysis	5
Insight into the role of myokines and myogenic regulatory factors under hypobaric hypoxia induced skeletal muscle loss	5
Prognostic value of pre-treatment advanced lung cancer inflammation index in non-small cell lung cancer: a meta-analysis	5
Cystatin C and mortality risk in the general population: systematic review and dose response meta-analysis	5
Shorter (GT)_n repeats in the haem-oxygenase 1 gene promoter are associated with better mid-term survival in subjects with coronary artery disease and abnormal ejection fraction	5
Protective effect of royal jelly on fluoride-induced nephrotoxicity in rats via the some protein biomarkers signalling pathways: a new approach for kidney damage	5
A meta-analysis of the effects of physical exercise on peripheral levels of a brain-derived neurotrophic factor in the elderly	5
Naringenin modulates Cobalt activities on gut motility through mechanosensors and serotonin signalling	4
Dermal exposure to cobalt studiedin vitroin keratinocytes – effects of cobalt exposure on inflammasome activated cytokines, and mRNA response	4
Urinary transferrin and proinflammatory markers predict the earliest diabetic nephropathy onset	4
Sub-acute oral toxicity study of aqueous extract of tobacco leaves (Nicotiana tabacum L.) on lipid profile, the tissue, and serum of the liver and kidney of male Wistar rats	4
Moringa seed-supplemented diets modulate ACE activity but not its gene expression in L-NAME-induced hypertensive rats	4
Potential biomarkers in endometrial cancer: a narrative review	4
A comparison of modelled serum cTnT and cTnI kinetics after 60 min swimming	4
Phytochemical constituents and protective efficacy ofSchefflera arboricolaL. leaves extract against thioacetamide-induced hepatic encephalopathy in rats	4
Comparison of fractional exhaled nitric oxide in asthmatics with and without allergic rhinitis	4
Inflammatory and coagulatory markers and exposure to different size fractions of particle mass, number and surface area air concentrations in the Swedish hard metal industry, in particular to cobalt	4
Protective effect of thymoquinone in preventing trauma-related damage: an experimental study	4
LCK, FOXC1 and hsa-miR-146a-5p as potential immune effector molecules associated with rheumatoid arthritis	4
miR-124-3p combined with miR-506-3p delay hepatic carcinogenesis via modulating sirtuin 1	4
Identification of colorectal neoplasia by using serum bile acid profile	4
Cyclic guanosine monophosphate and 10-year change in left ventricular mass: the Multi-Ethnic Study of Atherosclerosis (MESA)	4
Cardiac extracellular matrix modulation in a rat-diabetic model: biochemical and anti-oxidant beneficial effect of pomegranate (Punica granatum) peel extract	4
Hepatokine levels during the first or early second trimester of pregnancy and the subsequent risk of gestational diabetes mellitus: a systematic review and meta-analysis	4
Wild garlic extract reduces lipid peroxidation in terbuthylazine-treated human erythrocytes	4
Circulating microRNA-27a and -133a are negatively associated with incident hypertension: a five-year longitudinal population-based study	4
Value of miR-21 levels as potential biomarkers in the early diagnosis of hepatocellular carcinoma：a meta-analysis	4
Clinical significance of serum hepcidin in the diagnosis and treatment of patients with anemia of chronic disease: a meta-analysis	4
Persistently elevated levels of sST2 after acute coronary syndrome are associated with recurrent cardiac events	4
Detection and modification of biomarkers of inflammation determining successful rhythm control in patients with atrial fibrillation	4
Effect of milk thistle (Silybum marianum) supplementation on the serum levels of oxidative stress markers in male half marathon athletes	4
In vivo studies on the ameliorative effect of coconut water against carbon tetrachloride induced toxicity in rats	4
Topical and oral applications of Aloe vera improve healing of deep second-degree burns in rats via modulation of growth factors	4
Assessment of the relationship between semaphorin4D level and recurrence after catheter ablation in paroxysmal atrial fibrillation	4
Study on the daily Ad Libitum smoking habits of active Korean smokers and their effect on urinary smoking exposure and impact biomarkers	4
Can treatment response to SGLT2-inhibitors in syndrome of inappropriate antidiuresis be predicted by copeptin, natriuretic peptides and inflammatory markers?	4
Telomere length and signal joint T-cell receptor rearrangement excision circles as biomarkers for chronological age estimation	4
Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer	4
Long noncoding RNA as a potential diagnostic tool for prostate cancer: a systematic review and meta-analysis	4
Association between nutrient intake and telomere length in Japanese female university students	4
Machine learning revealed molecular classification of colorectal cancer with negative lymph node metastasis	4
Free lung desmosine: a potential biomarker for elastic fiber injury in pulmonary emphysema	4
Potential plasma microRNAs signature miR-190b-5p, miR-215-5p and miR-527 as non-invasive biomarkers for prostate cancer	3
Natural inhibitors for acetylcholinesterase and autophagy modulators as effective antagonists for tau and β-amyloid in Alzheimer’s rat model	3
Folate receptor alpha autoantibodies in children with autism spectrum disorder	3
Soluble urokinase plasminogen activator receptor and functionally relevant coronary artery disease: a prospective cohort study	3
Psidium guajava leaf extract improves gastrointestinal functions in rats and rabbits: an implication for ulcer and diarrhoea management	3
Chromosomal aberrations, DNA damage, and biochemical disturbances induced by silver nanoparticles in mice: role of particle size and natural compounds treatment	3
The significance of CD14 in clear cell renal cell carcinoma progression and survival prognosis	3
The association between inflammatory biomarkers and low back disorder: a systematic review and meta-analysis	3
Saponins from Panax japonicus alleviate adipose tissue fibrosis and metabolic dysfunction in high-fat-diet-induced obese mice	3
Cardio-protective effects of terminalia catappa leaves and terminalia chebula fruit extract in doxorubicin-induced cardiomyopathy in rats	3
Neuroprotective properties of solanum leaves in transgenic Drosophila melanogaster model of Alzheimer's disease	3
Association of red blood cell distribution width with post-operative new-onset atrial fibrillation following cardiac valve replacement surgery: a retrospective study	3
Examination of xylene exposure in the U.S. Population through biomonitoring: NHANES 2005–2006, 2011–2016	3
Thymidine kinase activity levels in serum can identify HR+ metastatic breast cancer patients with a low risk of early progression (SWOG S0226)	3
Compromised levels of CD6 and reduced T cell activation in the aged immune system	3
Pre-treatment systemic immune-inflammation index as a non-invasive biomarker for predicting clinical outcomes in patients with renal cell carcinoma: a meta-analysis of 20 studies	3
Downregulation of IRAIN long non-coding RNA predicts unfavourable clinical outcome in acute myeloid leukaemia patients	3
Circulating miRNA and cell-free DNA as a potential diagnostic tool in early detection of biliary tract cancer: a meta-analysis	3
Interpretation of myocardial injury subtypes in COVID-19 disease per fourth version of Universal Definition of Myocardial Infarction	3
Terminalia catappa attenuates phenylhydrazine-induced anaemia and hepato-renal toxicity in male Wistar rat by boosting blood cells, modulation of lipoproteins and up-regulation of in vivo	3
Associations between high-sensitivity C-reactive protein and non-communicable diseases in an Asian population: findings from the IFLS study	3
Admission biomarkers among patients with acute myocardial-infarction related cardiogenic shock with or without out-of-hospital cardiac arrest an exploratory study	3
Mitochondrial subtype MB-G3 contains potential novel biomarkers and therapeutic targets associated with prognosis of medulloblastoma	3
Tissue N-linked glycosylation as potential prognostic biomarker for biochemical recurrence-free survival	3
The clinical approach to diagnosing peri-procedural myocardial infarction after percutaneous coronary interventions according to the fourth universal definition of myocardial infarction – from the stu	3
Characterization of the association between cigarette smoking intensity and urinary concentrations of 2-hydroxyethyl mercapturic acid among exclusive cigarette smokers in the National Health and Nutri	3
Utilizing circulating tumour DNA as a prognostic predictor of gastric cancer: a meta-analysis	3

Protective effect of argan oil on DNA damage in vivo and in vitro