OOIR: Observatory of International Research

Papers

(The median citation count of Biomarkers is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Monitoring of hemostatic parameters for early prediction of first-trimester miscarriage	26
Cardiac extracellular matrix modulation in a rat-diabetic model: biochemical and anti-oxidant beneficial effect of pomegranate (Punica granatum) peel extract	25
Conjunctival microbiome changes in soft contact lens users and contact lens discomfort patients	25
Immunoadsorption for heart failure is associated with normalization of iron metabolism	21
Association of cardiac biomarkers with long-term cardiovascular events in a community cohort	19
Dexmedetomidine modulates mitochondrial dynamics to protect against endotoxin-induced lung injury via the protein kinase C-ɑ/haem oxygenase-1 signalling pathway	19
Neuroprotective effects of magnesium against stress induced by hydrogen peroxide in Wistar rat	17
Anti-diabetogenic and in vivo antioxidant activity of ethanol extract of Dryopteris dilatata in alloxan-induced male Wistar rats	17
Serum ferritin can serve as a biomarker for the prognosis and increased the prognostic predictive value of ISS/RISS in multiple myeloma patients	17
Free lung desmosine: a potential biomarker for elastic fiber injury in pulmonary emphysema	15
Nucleosome assembly protein 1-like 1 (NAP1L1) in gastric cancer patients: a potential biomarker with diagnostic and prognostic utility	14
Assessment of biomarkers of exposure and potential harm, and physiological and subjective health measures in exclusive users of nicotine pouches and current, former and never smokers	14
Serum prealbumin level as a biomarker of survival outcomes in patients with gastric cancer: a meta-analysis	14
A review ongarcinia kolaheckel: traditional uses, phytochemistry, pharmacological activities, and toxicology	13
Commentary: statistical analysis of 2 × 2 tables in biomarker studies 3) design, interpretation and guidelines	13
The predictive role of early CRP values for one-year mortality in the first 2 d after acute myocardial infarction	12
Alloimperatorin from Ammi majus fruits mitigates Piroxicam-provoked gastric ulcer and hepatorenal toxicity in ratsviasuppressing oxidative stress and apoptosis	12
δ_EPCD: the electrophysiologic coefficient of depressiveness	12
Hyponatremia in the emergency department: an overview of diagnostic and therapeutic approach	11
Asymmetric dimethylarginine level as biomarkers of cardiovascular or all-cause mortality in patients with chronic kidney disease: a meta-analysis	11
Insight into the role of myokines and myogenic regulatory factors under hypobaric hypoxia induced skeletal muscle loss	11
Investigation of exosomal tetraspanin profile in sepsis patients as a promising diagnostic biomarker	10
Programmed death-ligand 1 (PD-L1) expression predicts response to neoadjuvant chemotherapy in triple-negative breast cancer: a systematic review and meta-analysis	9
Determination of biomarkers of chlorine exposure from biological samples: a review of analysis techniques	9
The prognostic utility of galectin-3 in patients undergoing cardiac surgery: a scoping review	9

Serum and sputum MMP-9/TIMP-1 in winter sports athletes and swimmers: relationships with airway function	9
The role of pentraxin 3 and cathepsin B levels in pregnancies complicated by preeclampsia	9
Urinary anatalline and nicotelline cut-points to distinguish between exclusive and dual use of tobacco products	9
Commentary: statistical analysis of 2 × 2 tables in biomarker studies 2) study design and statistical tests	9
The significance of CD14 in clear cell renal cell carcinoma progression and survival prognosis	8
Pre-treatment systemic immune-inflammation index as a non-invasive biomarker for predicting clinical outcomes in patients with renal cell carcinoma: a meta-analysis of 20 studies	8
Topical and oral applications of Aloe vera improve healing of deep second-degree burns in rats via modulation of growth factors	8
Screening of radiation gastrointestinal injury biomarkers in rat plasma by high-coverage targeted lipidomics	8
The vasculogenic mimicry, CD146 ⁺ and CD105 ⁺ microvessel density in the prognosis of endometrioid endometrial adenocarcinoma: a s	8
Investigation of glial fibrillary acidic protein (GFAP) in body fluids as a potential biomarker for glioma: a systematic review and meta-analysis	8
Dynamine 3 as a diagnostic and prognostic biomarker in pancreatic cancer: Implications for early detection and targeted therapy	8
Validation of host cerebrospinal fluid protein biomarkers for early diagnosis of tuberculous meningitis in children: a replication and new biosignature discovery study	8
Perspectives on cardiovascular biomarkers: one fits all biomarkers are out, personalization is in	8
A future blood test for acute traumatic spinal cord injury	8
Admission biomarkers among patients with acute myocardial-infarction related cardiogenic shock with or without out-of-hospital cardiac arrest an exploratory study	7
Prognostic value of pre-treatment advanced lung cancer inflammation index in non-small cell lung cancer: a meta-analysis	7
Cystatin C and mortality risk in the general population: systematic review and dose response meta-analysis	7
Acute titanium dioxide nanoparticles exposure impaired spatial cognitive performance through neurotoxic and oxidative mechanisms in Wistar rats	7
High circulating microRNA-197 levels are associated with an increased risk of incident stroke among elderly survivors of the Great East Japan Earthquake	7
Expression levels of ACE and ACE2 in the placenta and white adipose tissue of lean and obese pregnant women	7
ERH is a prognostic biomarker associated with immune cell infiltration in lung cancer	7
The effects of anabolic-androgenic steroids on DNA damage in bodybuilders’ blood lymphocytes	7
MicroRNA profile as potential molecular signature for attention deficit hyperactivity disorder in children	7
Analytical factors and interpretative issues in red blood cell distribution width and their impact on the atrial fibrillation literature	6
Evaluating the activity of salivary enzymes as stress biomarkers under psychological stress and their relationship with rumination and personality traits	6
Arginase is upregulated in healthy women infected by oncogenic HPV types	6
CD105-microvessel density analysis and its clinical value in urothelial carcinoma of bladder patients	6
Protective effect of thymoquinone in preventing trauma-related damage: an experimental study	6
Clinical significance of Talin-1 and HER-2 status in different types of gastric carcinoma	6
The association between systemic inflammation markers and the risk of incident dilated cardiomyopathy: a prospective study of 351,148 participants	6
Localization and characterization of proenkephalin-A as a potential biomarker for kidney disease in murine and human kidneys	6
Bromuconazole fungicide induces cell cycle arrest and apoptotic cell death in cultured human colon carcinoma cells (HCT116) via oxidative stress process	6
Serum neurofilament light chain in functionally relevant coronary artery disease and adverse cardiovascular outcomes	5
Downregulation of IRAIN long non-coding RNA predicts unfavourable clinical outcome in acute myeloid leukaemia patients	5
Usability of presepsin, calprotectin, and interleukin 6 in the diagnosis of acute appendicitis	5
Apoptotic and anti-angiogenic effects of propolis against human bladder cancer: molecular docking and in vitro screening	5
Characterization of the association between cigarette smoking intensity and urinary concentrations of 2-hydroxyethyl mercapturic acid among exclusive cigarette smokers in the National Health and Nutri	5
The role of maternal serum ischemia-modified albumin in the prediction of hyperemesis gravidarum: a prospective cohort study	5
Evaluation of the role of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and mean platelet volume (MPV) time series as predictors of diagnosis and prognosis of hemotoxic snak	5
Utilizing circulating tumour DNA as a prognostic predictor of gastric cancer: a meta-analysis	5
Phytochemical constituents and protective efficacy ofSchefflera arboricolaL. leaves extract against thioacetamide-induced hepatic encephalopathy in rats	5
Polymorphisms in ERCC1, ERCC4 and ERCC5 genes as biomarkers of susceptibility for pesticide-induced DNA damage in North-West Indian agricu	5
Exploring the potential of humanin as a biomarker for early breast cancer detection: a study of serum levels and diagnostic performance	5
Persistently elevated levels of sST2 after acute coronary syndrome are associated with recurrent cardiac events	5
Probiotics as a targeted intervention in anti-ageing: a review	5
Commentary: statistical analysis of 2 × 2 tables in biomarker studies 1) the four ‘indices of test validity’	4
Exposure to pesticides and oxidative stress in Brazilian agricultural communities	4
A prognostic risk model based on lactate metabolism and transport-related lncRNAs for gastric adenocarcinoma	4
The ischaemia-modified albumin test: new tricks for an old dog?	4
Study on the daily Ad Libitum smoking habits of active Korean smokers and their effect on urinary smoking exposure and impact biomarkers	4

Associations between high-sensitivity C-reactive protein and non-communicable diseases in an Asian population: findings from the IFLS study	4
Usefulness of serum procalcitonin and point-of-care multiplex PCR gastro-intestinal panel in acute diarrhoea or colitis in the emergency department	4
Cancer stem cells (CSCs): key player of radiotherapy resistance and its clinical significance	4
Exosomal therapy mitigates silver nanoparticles-induced neurotoxicity in rats	4
The diagnostic value of serum YKL-40 in endometrial cancer: a meta-analysis	4
Risk factors for Staphylococcus aureus colonization in a general emergency department patient cohort – results of an observational cohort study	4
Serum biomarkers for monitoring response to tuberculosis treatment: an assessment of the effect of different covariates among slow and fast treatment responders	4
Abstracts for the 17 ^th Annual Biomarkers and Personalized Medicine in Cardiovascular Disease Symposium	4
Plukenetia conophora seed oil ameliorates streptozotocin-induced hyperglycaemia and oxidative stress in rats	4
Potential biomarkers in endometrial cancer: a narrative review	4
In vivo studies on the ameliorative effect of coconut water against carbon tetrachloride induced toxicity in rats	4
Role of procalcitonin, C-reactive protein and ferritin in cytokine release syndrome after CAR T-cell therapy in children and young adults	4
Integrated bioinformatics approach for the identification and validation of novel biomarkers in ACC progression and prognosis	4
Circulating microRNA-27a and -133a are negatively associated with incident hypertension: a five-year longitudinal population-based study	4
Identification of ion channel-related genes as diagnostic markers and potential therapeutic targets for osteoarthritis through bioinformatics and machine learning-based approaches	4
Predictors of long-term all-cause mortality after carotid artery stenting: evaluation of the Naples prognostic score	4
Importance of mannose-binding lectin2 polymorphism (rs1800450) in infections in children	4
Integrated analysis of mRNA–m⁶A–protein profiles reveals novel insights into the mechanisms for cadmium-induced urothelial transformation	4
Association of red blood cell distribution width with post-operative new-onset atrial fibrillation following cardiac valve replacement surgery: a retrospective study	4
Neuroprotective role of medicinal plant extracts evaluated in a scopolamine-induced rat model of Alzheimer's disease	4
A systematic review of first-trimester blood biomarkers associated with preterm prelabor rupture of the fetal membranes	4
The association of von willebrand factor and its cleaving protease (ADAMTS13) with health behaviours in young black and white adults: the African-PREDICT study	3
Impact of switching from cigarette smoking to tobacco heating system use on biomarkers of potential harm in a randomized trial	3
The role of Matrix Metalloproteinase-2 and Galectin-3 as predictive biomarkers for all-cause mortality in patients undergoing transfemoral transcatheter aortic valve implantation	3
Leaf extract ofAnacardium occidentaleameliorates biomarkers of neuroinflammation, memory loss, and neurobehavioral deficit in N(ω)-nitro-L-arginine methyl ester (L-NAME) treated rats	3
Severity prediction markers in dengue: a prospective cohort study using machine learning approach	3
Toxic effect of carpet dust on the biochemical indices and histological structure of the lung in rats: the potential role of cytochrome P450 2E1 and extracellular signal-regulated kinase/mitogen-activ	3
Diagnostic value of CRP for predicting the severity of acute pancreatitis: a systematic review and meta-analysis	3
Histopathological evaluation of the effects of dexmedetomidine against pituitary damage ınduced by X-ray irradiation	3
The tumour/normal tissue ratio of Keap1 protein is a predictor for lymphovascular invasion in colorectal cancer: a correlation study between the Nrf2 and KRas pathways	3
Effect of waterpipe smoking and its cessation on metabolic biomarkers and a novel biomarker omentin-1	3
Lower vitamin D levels and VDR FokI variants are associated with susceptibility to sepsis: a hospital-based case-control study	3
Predictive biomarkers for colorectal cancer: a state-of-the-art systematic review	3
Cardio-protective effects of terminalia catappa leaves and terminalia chebula fruit extract in doxorubicin-induced cardiomyopathy in rats	3
Gestational diabetes mellitus and inflammatory biomarkers of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio: a systematic review and meta-analysis	3
Expression and clinical significance of miR-421 in prostate cancer	3
Circulating level of serum secreted frizzled-related protein 5 decreases in polycystic ovary syndrome	3
Role of exosomes and its emerging therapeutic applications in the pathophysiology of non-infectious diseases	3
Gastro-protective effect ofArtemisia Sieberiessential oil against ethanol-induced ulcer in rats as revealed via biochemical, histopathological and metabolomics analysis	3
ZNF503 combined with GATA3 is a prognostic factor in triple-negative breast cancer	2
Relationships between Charlson comorbidity index associated biomarkers and outcomes among participants in the Malmö diet and cancer study	2
Interpreting quantitative RNA expression prognostic and predictive results generated from synchronous rather than solitary breast cancers	2
A data mining approach to identify key radioresponsive genes in mouse model of radiation-induced intestinal injury	2
The reversed De Ritis ratio for predicting in-hospital mortality among intensive care patients with organophosphate poisoning	2
The first evidence of microplastic uptake in natural freshwater mussel,Unio stevenianusfrom Karasu River, Turkey	2
The association between inflammatory biomarkers and low back disorder: a systematic review and meta-analysis	2
Analysis of urinary kallikrein-related peptidase 13 for monitoring bladder cancer	2
The role of differentially expressed miR-660 in peripheral blood lymphocytes of patients with pulmonary tuberculosis	2
Interpretation of myocardial injury subtypes in COVID-19 disease per fourth version of Universal Definition of Myocardial Infarction	2
Testing the accuracy of a four serum microRNA panel for the detection of primary bladder cancer: a discovery and validation study	2
Cissus quadrangularis extract mitigates diabetic cardiomyopathy by inhibiting RAAS activation, inflammation and oxidative stress	2
Justicia carnea extracts ameliorated hepatocellular damage in streptozotocin-induced type 1 diabetic male rats via decrease in oxidative stress, inflammation and increasing other risk markers	2
Abstracts for the 18 ^th Annual Biomarkers and Personalized Medicine in Cardiovascular Disease Symposium	2
The safety and efficacy of CAR-T cells in the treatment of prostate cancer: review	2
High-tissue FRMD6 expression predicts better outcomes among colorectal cancer patients	2
Clinical value of prokineticin 2 in the diagnosis of neonatal necrotizing enterocolitis	2
Saponins from Panax japonicus alleviate adipose tissue fibrosis and metabolic dysfunction in high-fat-diet-induced obese mice	2
Construction of a cell cycle-specific lncRNA-miRNA-mRNA network reveals novel key lncRNAs in colorectal cancer	2
In vivo assessment of inflammatory cytokines induced oxidative stress signalling, and troponin I gene dysregulation in cardiac tissue associated with chronic administration of bolde	2
Correction	2
Recovery of systemic hyperinflammation in patients with severe SARS-CoV-2 infection	2
Prognostic prediction of oxidative stress related hematological biomarkers in locally advanced cervical cancer patients undergoing chemoradiotherapy	2
Upregulation of LncRNAs G2E3-AS1 and BACE1-AS as prognostic biomarkers in metastatic colorectal cancer	2
Detection of MET gene somatic mutations in hepatocellular carcinoma of Egyptian patients using next-generation sequencing	2
Longitudinal profile of circulating endothelial cells in post-acute coronary syndrome patients	2
FYB methylation in peripheral blood as a potential marker for the early-stage lung cancer: a case-control study in Chinese population	2
Circulating miRNA and cell-free DNA as a potential diagnostic tool in early detection of biliary tract cancer: a meta-analysis	2