OOIR: Observatory of International Research

Papers

(The TQCC of Progress in Retinal and Eye Research is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
In vivo application of base and prime editing to treat inherited retinal diseases	267
Widefield OCT angiography	158
Cell identity changes in ocular surface Epithelia	148
The neuroimmune interface in retinal regeneration	145
Phenotyping and genotyping FEVR: Molecular genetics, clinical and imaging features, and therapeutics	143
International consensuses and controversies on causes, diagnosis and management of diabetic macular edema (DME)	121
Non-vasogenic cystoid maculopathies	115
Animal models for the evaluation of retinal stem cell therapies	111
Editorial Board	109
Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	106
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	104
Central serous chorioretinopathy: An evidence-based treatment guideline	101
Corneal stromal repair and regeneration	101
Unravelling CYP4V2: Clinical features, genetic insights, pathogenic mechanisms and therapeutic strategies in Bietti crystalline corneoretinal dystrophy	100
Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration	93
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas	86
Editorial Board	80
A paradigm shift in retinal detachment repair: The concept of integrity	80
Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors	80
Risk factors, clinical features and treatment of Behçet's disease uveitis	76
Squishy matters – Corneal mechanobiology in health and disease	75
Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)	73
Homeostatic plasticity in the retina	73
Myocilin misfolding and glaucoma: A 20-year update	72
Cell fate decisions, transcription factors and signaling during early retinal development	72

Editorial Board	71
The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease	71
Protection against corneal hyperosmolarity with soft-contact-lens wear	71
Approaches for corneal endothelium regenerative medicine	69
How gut microbiota may impact ocular surface homeostasis and related disorders	69
Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration	67
The retinal pigmentation pathway in human albinism: Not so black and white	65
RNA-targeting strategies as a platform for ocular gene therapy	65
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	62
Genetic architecture of congenital cataracts: correlation of pathogenic variants with morphology and clinical outcomes	62
Cellular component transfer between photoreceptor cells of the retina	62
Rhodopsin, light-sensor of vision	60
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	60
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	59
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	55
Optical coherence tomography angiography in diabetic retinopathy	52
Regulation of lens water content: Effects on the physiological optics of the lens	51
Editorial Board	51
Pentosan polysulfate maculopathy: clinical considerations, pathobiology, and causality	50
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	50
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	50
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	49
Interventions to reduce incidence and progression of myopia in children and adults	49
Retinal pigment epithelium 65 kDa protein (RPE65): An update	48
Editorial Board	46
The march to harmonized imaging standards for retinal imaging	45
Bacterial keratitis: identifying the areas of clinical uncertainty	44
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	43
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	42
Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)	41
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	41
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	41
Artificial intelligence in ophthalmology: Progress, challenges, and ethical implications	40
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	40
Clinical histopathology and pathogenesis of macular telangiectasia type 2	40
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	39