OOIR: Observatory of International Research

Papers

(The median citation count of Progress in Retinal and Eye Research is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Cell identity changes in ocular surface Epithelia	385
The neuroimmune interface in retinal regeneration	280
In vivo application of base and prime editing to treat inherited retinal diseases	217
Posterior capsule opacification: What's in the bag?	217
Non-vasogenic cystoid maculopathies	212
Immunological aspects of RPE cell transplantation	204
Promises and pitfalls of evaluating photoreceptor-based retinal disease with adaptive optics scanning light ophthalmoscopy (AOSLO)	193
Animal models for the evaluation of retinal stem cell therapies	150
Targeting complement components C3 and C5 for the retina: Key concepts and lingering questions	144
Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	128
Editorial Board	124
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	123
Corneal stromal repair and regeneration	123
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas	121
Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration	112
Central serous chorioretinopathy: An evidence-based treatment guideline	111
Editorial Board	103
Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)	100
Homeostatic plasticity in the retina	100
A paradigm shift in retinal detachment repair: The concept of integrity	96
Myocilin misfolding and glaucoma: A 20-year update	90
Risk factors, clinical features and treatment of Behçet's disease uveitis	90
Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors	87
Digital technology, tele-medicine and artificial intelligence in ophthalmology: A global perspective	87
Squishy matters – Corneal mechanobiology in health and disease	84

Photocoagulation for retinal vein occlusion	84
Uncoupling proteins in the mitochondrial defense against oxidative stress	81
Cell fate decisions, transcription factors and signaling during early retinal development	80
Editorial Board	79
Protection against corneal hyperosmolarity with soft-contact-lens wear	79
The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease	79
Patient derived stem cells for discovery and validation of novel pathogenic variants in inherited retinal disease	78
The retinal pigmentation pathway in human albinism: Not so black and white	74
How gut microbiota may impact ocular surface homeostasis and related disorders	73
RNA-targeting strategies as a platform for ocular gene therapy	72
Approaches for corneal endothelium regenerative medicine	70
Photoreceptor cells and RPE contribute to the development of diabetic retinopathy	68
The vital role for nitric oxide in intraocular pressure homeostasis	66
Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration	66
Clinical vision and molecular loss: Integrating visual psychophysics with molecular genetics reveals key details of normal and abnormal visual processing	64
Cellular component transfer between photoreceptor cells of the retina	61
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	61
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	61
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	60
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	60
Optical coherence tomography angiography in diabetic retinopathy	60
Editorial Board	58
Rhodopsin, light-sensor of vision	58
Corneal endothelial dysfunction: Evolving understanding and treatment options	58
Regulation of lens water content: Effects on the physiological optics of the lens	58
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	57
The retinal pigment epithelium: Development, injury responses, and regenerative potential in mammalian and non-mammalian systems	56
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	56
Retinal pigment epithelium 65 kDa protein (RPE65): An update	56
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	56
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	55
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	54
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	54
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	53
Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)	53
Zinn's zonule	53
Bacterial keratitis: identifying the areas of clinical uncertainty	52
VEGFR1 signaling in retinal angiogenesis and microinflammation	51
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	50
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	49
Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases	49
Past, present and future role of retinal imaging in neurodegenerative disease	48
Editorial Board	47
Tilted disc syndrome (TDS): New hypotheses for posterior segment complications and their implications in other retinal diseases	47
Aqueous outflow regulation – 21st century concepts	46
Eye on the horizon: The metabolic landscape of the RPE in aging and disease	46
Optic nerve head anatomy in myopia and glaucoma, including parapapillary zones alpha, beta, gamma and delta: Histology and clinical features	44
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation	44
Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies,	43
Prospects for the application of Müller glia and their derivatives in retinal regenerative therapies	41

Fundus-controlled perimetry (microperimetry): Application as outcome measure in clinical trials	40
The relationship between intraocular pressure and glaucoma: An evolving concept	39
Healing the cornea: Exploring the therapeutic solutions offered by MSCs and MSC-derived EVs	38
Syndromic Retinitis Pigmentosa	38
Value proposition of retinal imaging in Alzheimer's disease screening: A review of eight evolving trends	38
Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy	37
Zebrafish and inherited photoreceptor disease: Models and insights	36
Familial normal tension glaucoma genetics	35
The multifunctional human ocular melanocortin system	35
Dominant optic atrophy: Culprit mitochondria in the optic nerve	35
Potential therapeutic targets for age-related macular degeneration: The nuclear option	34
Müller cells and astrocytes in tractional macular disorders	34
The dark and bright sides of retinal G protein-coupled receptor (RGR) in vision and disease	32
Translation of single-cell transcriptomic analysis of uveal melanomas to clinical oncology	32
Characterizing Bruch's membrane: State-of-the-art imaging, computational segmentation, and biologic models in retinal disease and health	30
Cellular and subcellular optogenetic approaches towards neuroprotection and vision restoration	29
Editorial Board	29
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy	28
A reinterpretation of critical flicker-frequency (CFF) data reveals key details about light adaptation and normal and abnormal visual processing	28
Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms	27
The two-faced effects of nerves and neuropeptides in corneal diseases	26
Latest advances in white spot syndromes: New findings and interpretations	26
The X-linked retinopathies: Physiological insights, pathogenic mechanisms, phenotypic features and novel therapies	26
Editorial Board	24
Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease	24
Ocular manifestations of COVID-19	24
Editorial Board	22
The AI revolution in glaucoma: Bridging challenges with opportunities	22
Editorial Board	22
Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice	22
Müller cells trophism and pathology as the next therapeutic targets for retinal diseases	21
Optical coherence tomography in the management of diabetic macular oedema	21
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation	21
The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: More than cellular clean up	21
Comparative insights into the role of sex hormones in glaucoma among women and men	20
Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications	20
Age and intraocular pressure in murine experimental glaucoma	20
Advances in understanding the molecular structure of retinoschisin while questions remain of biological function	20
Corrigendum to “Splicing mutations in inherited retinal diseases” [Prog. Retin. Eye Res. 80 (2021) 100874]	20
Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration	20
Single-cell RNA sequencing in vision research: Insights into human retinal health and disease	20
In vitro and ex vivo models of microbial keratitis: Present and future	19
Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches	18
Therapy with voretigene neparvovec. How to measure success?	18
Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy	17
Immune responses to retinal gene therapy using adeno-associated viral vectors – Implications for treatment success and safety	17
The role of the gut microbiome in eye diseases	17
AI in the clinical management of GA: A novel therapeutic universe requires novel tools	17
Diabetic macular ischaemia- a new therapeutic target?	17
Artificial intelligence in OCT angiography	17
Inherited retinal diseases: Linking genes, disease-causing variants, and relevant therapeutic modalities	15
Toward an internationally accepted standard for reading charts	15