OOIR: Observatory of International Research

Papers

(The median citation count of Progress in Retinal and Eye Research is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
The neuroimmune interface in retinal regeneration	275
In vivo application of base and prime editing to treat inherited retinal diseases	169
Widefield OCT angiography	150
Cell identity changes in ocular surface Epithelia	149
Phenotyping and genotyping FEVR: Molecular genetics, clinical and imaging features, and therapeutics	148
Animal models for the evaluation of retinal stem cell therapies	126
Non-vasogenic cystoid maculopathies	121
International consensuses and controversies on causes, diagnosis and management of diabetic macular edema (DME)	113
Editorial Board	112
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	110
Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration	108
Central serous chorioretinopathy: An evidence-based treatment guideline	107
Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	106
Unravelling CYP4V2: Clinical features, genetic insights, pathogenic mechanisms and therapeutic strategies in Bietti crystalline corneoretinal dystrophy	101
Corneal stromal repair and regeneration	99
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas	90
Editorial Board	85
Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors	83
Homeostatic plasticity in the retina	83
A paradigm shift in retinal detachment repair: The concept of integrity	82
Squishy matters – Corneal mechanobiology in health and disease	79
Myocilin misfolding and glaucoma: A 20-year update	78
Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)	76
Risk factors, clinical features and treatment of Behçet's disease uveitis	74
Cell fate decisions, transcription factors and signaling during early retinal development	74

The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease	73
Femtosecond lasers in ophthalmology: Mechanisms, clinical breakthroughs, and multidisciplinary frontiers	72
RNA-targeting strategies as a platform for ocular gene therapy	72
Editorial Board	71
Protection against corneal hyperosmolarity with soft-contact-lens wear	71
Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration	68
Genetic architecture of congenital cataracts: correlation of pathogenic variants with morphology and clinical outcomes	68
The retinal pigmentation pathway in human albinism: Not so black and white	66
How gut microbiota may impact ocular surface homeostasis and related disorders	66
Approaches for corneal endothelium regenerative medicine	64
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	63
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	63
Rhodopsin, light-sensor of vision	61
Cellular component transfer between photoreceptor cells of the retina	60
Optical coherence tomography angiography in diabetic retinopathy	58
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	57
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	56
Editorial Board	53
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	52
Pentosan polysulfate maculopathy: clinical considerations, pathobiology, and causality	52
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	51
Interventions to reduce incidence and progression of myopia in children and adults	50
Beyond convolutions and supervised learning with transformers and representation learning for retinal image analysis	50
Retinal pigment epithelium 65 kDa protein (RPE65): An update	50
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	48
Regulation of lens water content: Effects on the physiological optics of the lens	47
Editorial Board	46
The march to harmonized imaging standards for retinal imaging	44
Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)	43
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	43
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	43
Quantitative analysis of conjunctival vascular alterations: Applications in ocular and systemic disease detection	43
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	42
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	42
Bacterial keratitis: identifying the areas of clinical uncertainty	42
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	41
Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases	40
Clinical histopathology and pathogenesis of macular telangiectasia type 2	39
The ocular surface in type 2 diabetes: pathophysiology and impact of anti-diabetic drugs	38
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	38
Tilted disc syndrome (TDS): New hypotheses for posterior segment complications and their implications in other retinal diseases	35
Editorial Board	35
Artificial intelligence in ophthalmology: Progress, challenges, and ethical implications	35
The relationship between intraocular pressure and glaucoma: An evolving concept	34
Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies,	34
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation	33
Potential therapeutic targets for age-related macular degeneration: The nuclear option	32
Eye on the horizon: The metabolic landscape of the RPE in aging and disease	32
The dark and bright sides of retinal G protein-coupled receptor (RGR) in vision and disease	31
Zebrafish and inherited photoreceptor disease: Models and insights	30

Syndromic retinitis pigmentosa	30
Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy	30
Müller cells and astrocytes in tractional macular disorders	29
Decoding pediatric inherited retinal dystrophies: Bridging genetic complexity and clinical heterogeneity	29
Value proposition of retinal imaging in Alzheimer's disease screening: A review of eight evolving trends	28
Glymphatic Transport and Ocular Diseases	27
Healing the cornea: Exploring the therapeutic solutions offered by MSCs and MSC-derived EVs	27
The multifunctional human ocular melanocortin system	26
Familial normal tension glaucoma genetics	26
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy	25
Corrigendum to “Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease” [Progr. Retin. Eye Res. 106 (2025) 101362]	25
Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms	25
Characterizing Bruch's membrane: State-of-the-art imaging, computational segmentation, and biologic models in retinal disease and health	25
Cellular and subcellular optogenetic approaches towards neuroprotection and vision restoration	24
A reinterpretation of critical flicker-frequency (CFF) data reveals key details about light adaptation and normal and abnormal visual processing	24
Imaging of the retinal hypoxia: A journey from oxygen microelectrode to the first hypoxia imaging in the living retina	24
Editorial Board	24
The two-faced effects of nerves and neuropeptides in corneal diseases	24
Latest advances in white spot syndromes: New findings and interpretations	23
Pericytes in the optic nerve head	23
Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease	23
Ocular manifestations of COVID-19	23
Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice	23
The AI revolution in glaucoma: Bridging challenges with opportunities	23
Eyelid dermatitis: Work-up and future diagnostic innovative solutions	22
The versatile roles of retinal pigment epithelium in the pathophysiology of retinitis pigmentosa	22
Editorial Board	21
Age and intraocular pressure in murine experimental glaucoma	21
Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration	21
Shining light on CRISPR/Cas9 therapeutics for inherited retinal diseases	21
Müller cells trophism and pathology as the next therapeutic targets for retinal diseases	20
Optical coherence tomography in the management of diabetic macular oedema	20
The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: More than cellular clean up	19
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation	19
Advances in understanding the molecular structure of retinoschisin while questions remain of biological function	19
Corrigendum to “Splicing mutations in inherited retinal diseases” [Prog. Retin. Eye Res. 80 (2021) 100874]	18
Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications	18
Safety and effectiveness of vital dyes for intraocular surgery	17
Therapy with voretigene neparvovec. How to measure success?	16
The physiology of dark adaptation: Progress and future directions	16
Zinc in eye health, retinal biology and disease	16
In vitro and ex vivo models of microbial keratitis: Present and future	15
Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches	15
Eyes shut homolog (EYS): Connecting molecule to disease	15
The role of the gut microbiome in eye diseases	14
AI in the clinical management of GA: A novel therapeutic universe requires novel tools	14
Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy	14
Bisretinoid lipofuscin, fundus autofluorescence and retinal disease	14
Diabetic macular ischaemia- a new therapeutic target?	14
Comparative insights into the role of sex hormones in glaucoma among women and men	14
Editorial Board	13
Inherited retinal diseases: Linking genes, disease-causing variants, and relevant therapeutic modalities	13
AI explainability in oculomics: How it works, its role in establishing trust, and what still needs to be addressed	13
Editorial Board	13
Corrigendum to “Widefield OCT angiography” [Progress in Retinal and Eye Research. 107 (2025) 101378]	13