OOIR: Observatory of International Research

Papers

(The median citation count of Progress in Retinal and Eye Research is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Heparan sulfate proteoglycans (HSPGs) of the ocular lens	340
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	231
Addressing neurodegeneration in glaucoma: Mechanisms, challenges, and treatments	185
Clinical vision and molecular loss: Integrating visual psychophysics with molecular genetics reveals key details of normal and abnormal visual processing	182
In vivo application of base and prime editing to treat inherited retinal diseases	178
Editorial Board	172
Editorial Board	167
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	126
Translation of single-cell transcriptomic analysis of uveal melanomas to clinical oncology	115
Cell identity changes in ocular surface Epithelia	106
The genetics and disease mechanisms of rhegmatogenous retinal detachment	102
Toward an internationally accepted standard for reading charts	100
Editorial Board	96
IOP and glaucoma damage: The essential role of optic nerve head and retinal mechanosensors	95
Posterior capsule opacification: What's in the bag?	95
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	91
Cellular component transfer between photoreceptor cells of the retina	87
Standard automated perimetry for glaucoma and diseases of the retina and visual pathways: Current and future perspectives	82
Role of glia in optic nerve	80
Of men and mice: Human X-linked retinoschisis and fidelity in mouse modeling	78
Early and late stage gene therapy interventions for inherited retinal degenerations	77
Congenital aniridia beyond black eyes: From phenotype and novel genetic mechanisms to innovative therapeutic approaches	77
Pathogenesis of ocular toxoplasmosis	72
Optical coherence tomography angiography in diabetic retinopathy	71
Rhodopsin, light-sensor of vision	71

Inflammation in Glaucoma: From the back to the front of the eye, and beyond	69
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	69
The innate immune system in diabetic retinopathy	69
Crosslinking with UV-A and riboflavin in progressive keratoconus: From laboratory to clinical practice – Developments over 25 years	67
Retinal pigment epithelium 65 kDa protein (RPE65): An update	67
A reinterpretation of critical flicker-frequency (CFF) data reveals key details about light adaptation and normal and abnormal visual processing	64
Alzheimer's disease pathophysiology in the Retina	64
Editorial Board	62
Editorial Board	62
Editorial Board	60
Editorial Board	60
It is time for a moonshot to find “Cures” for diabetic retinal disease	58
Corneal endothelial dysfunction: Evolving understanding and treatment options	58
Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA)	57
Cellular and subcellular optogenetic approaches towards neuroprotection and vision restoration	56
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	53
Modeling complex age-related eye disease	52
Non-vasogenic cystoid maculopathies	51
Editorial Board	50
Corneal cross-linking	49
pH in the vertebrate retina and its naturally occurring and pathological changes	49
Recent understanding of binocular vision in the natural environment with clinical implications	48
Reticular pseudodrusen: A critical phenotype in age-related macular degeneration	47
Extraocular, periocular, and intraocular routes for sustained drug delivery for glaucoma	47
Promises and pitfalls of evaluating photoreceptor-based retinal disease with adaptive optics scanning light ophthalmoscopy (AOSLO)	47
Immunological aspects of RPE cell transplantation	46
Regulation of lens water content: Effects on the physiological optics of the lens	46
Pathobiology of the crystalline lens in Stickler syndrome	45
Shedding light on myopia by studying complete congenital stationary night blindness	45
The retinal pigment epithelium: Development, injury responses, and regenerative potential in mammalian and non-mammalian systems	44
The two-faced effects of nerves and neuropeptides in corneal diseases	44
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	44
The X-linked retinopathies: Physiological insights, pathogenic mechanisms, phenotypic features and novel therapies	43
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	43
Implications of genetic variation in the complement system in age-related macular degeneration	43
Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms	42
Retinal vessel diameters and function in cardiovascular risk and disease	41
Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease	41
Molecular bases of rod and cone differences	40
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	39
Latest advances in white spot syndromes: New findings and interpretations	39
Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis	39
From randomised controlled trials to real-world data: Clinical evidence to guide management of diabetic macular oedema	38
Ocular manifestations of COVID-19	37
Chromatic visual evoked potentials: A review of physiology, methods and clinical applications	36
Editorial Board	36
The novel role of lymphatic vessels in the pathogenesis of ocular diseases	36
Studies of the retinal microcirculation using human donor eyes and high-resolution clinical imaging: Insights gained to guide future research in diabetic retinopathy	36
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	34
Retinal changes in Alzheimer's disease— integrated prospects of imaging, functional and molecular advances	33

Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	32
Personalising surgical treatments for glaucoma patients	32
Endpoints for clinical trials in ophthalmology	30
The pre-Descemet's layer (Dua's layer, also known as the Dua-Fine layer and the pre-posterior limiting lamina layer): Discovery, characterisation, clinical and surgical applications, and the controver	30
Editorial Board	29
Editorial Board	28
Zinn's zonule	28
Editorial Board	28
Paracentral acute middle maculopathy and the organization of the retinal capillary plexuses	26
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas	26
Venous overload choroidopathy: A hypothetical framework for central serous chorioretinopathy and allied disorders	25
Metastatic uveal melanoma: The final frontier	25
Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)	24
The role of dark adaptation in understanding early AMD	24
Detecting retinal cell stress and apoptosis with DARC: Progression from lab to clinic	24
Resilience to diabetic retinopathy	24
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	23
Optical coherence tomography angiography of the retina and choroid in systemic diseases	23
The AI revolution in glaucoma: Bridging challenges with opportunities	23
Central serous chorioretinopathy: An evidence-based treatment guideline	23
Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration	22
Bacterial keratitis: identifying the areas of clinical uncertainty	21
Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice	20
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	20
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	20
Dynamic lipid turnover in photoreceptors and retinal pigment epithelium throughout life	19
VEGFR1 signaling in retinal angiogenesis and microinflammation	19
Role of epigenetics in corneal health and disease	18
Targeting complement components C3 and C5 for the retina: Key concepts and lingering questions	18
Efficacy in myopia control	18
Corneal stromal repair and regeneration	18
Retina in a dish: Cell cultures, retinal explants and animal models for common diseases of the retina	18
Regulation of epigenetic homeostasis in uveal melanoma and retinoblastoma	17
Optogenetics for visual restoration: From proof of principle to translational challenges	17
Retinal capillary basement membrane thickening: Role in the pathogenesis of diabetic retinopathy	17
Mesenchymal stromal cells for the treatment of ocular autoimmune diseases	17
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	17
Myocilin misfolding and glaucoma: A 20-year update	16
Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases	15
Editorial Board	15
Editorial Board	14
Insights into the developing fovea revealed by imaging	14
Editorial Board	14
Editorial Board	14
Non-specific orbital inflammation: Current understanding and unmet needs	13
Targeting RGD-binding integrins as an integrative therapy for diabetic retinopathy and neovascular age-related macular degeneration	13
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	13
Clusterin, other extracellular chaperones, and eye disease	13
The genetic basis for adult onset glaucoma: Recent advances and future directions	13
Past, present and future role of retinal imaging in neurodegenerative disease	13
Amblyopia and the whole child	13