OOIR: Observatory of International Research

Papers

(The median citation count of Progress in Retinal and Eye Research is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Widefield OCT angiography	261
The neuroimmune interface in retinal regeneration	156
In vivo application of base and prime editing to treat inherited retinal diseases	146
Cell identity changes in ocular surface Epithelia	143
Animal models for the evaluation of retinal stem cell therapies	138
Phenotyping and genotyping FEVR: Molecular genetics, clinical and imaging features, and therapeutics	114
International consensuses and controversies on causes, diagnosis and management of diabetic macular edema (DME)	111
Non-vasogenic cystoid maculopathies	110
Editorial Board	108
Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	105
Central serous chorioretinopathy: An evidence-based treatment guideline	100
Unravelling CYP4V2: Clinical features, genetic insights, pathogenic mechanisms and therapeutic strategies in Bietti crystalline corneoretinal dystrophy	99
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	98
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas	97
Corneal stromal repair and regeneration	96
Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration	89
Editorial Board	86
A paradigm shift in retinal detachment repair: The concept of integrity	83
Homeostatic plasticity in the retina	79
Squishy matters – Corneal mechanobiology in health and disease	78
Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)	77
Photocoagulation for retinal vein occlusion	74
Myocilin misfolding and glaucoma: A 20-year update	73
Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors	72
Risk factors, clinical features and treatment of Behçet's disease uveitis	70

Cell fate decisions, transcription factors and signaling during early retinal development	70
The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease	70
RNA-targeting strategies as a platform for ocular gene therapy	69
Editorial Board	69
Protection against corneal hyperosmolarity with soft-contact-lens wear	67
How gut microbiota may impact ocular surface homeostasis and related disorders	66
The retinal pigmentation pathway in human albinism: Not so black and white	66
Genetic architecture of congenital cataracts: correlation of pathogenic variants with morphology and clinical outcomes	66
Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration	64
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	64
Approaches for corneal endothelium regenerative medicine	64
Cellular component transfer between photoreceptor cells of the retina	63
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	62
Optical coherence tomography angiography in diabetic retinopathy	61
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	60
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	59
Editorial Board	58
Rhodopsin, light-sensor of vision	58
Regulation of lens water content: Effects on the physiological optics of the lens	55
Interventions to Reduce Incidence and Progression of Myopia in Children and Adults	54
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	52
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	51
Retinal pigment epithelium 65 kDa protein (RPE65): An update	50
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	49
The retinal pigment epithelium: Development, injury responses, and regenerative potential in mammalian and non-mammalian systems	48
Pentosan polysulfate maculopathy: clinical considerations, pathobiology, and causality	48
Editorial Board	48
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	47
The march to harmonized imaging standards for retinal imaging	46
Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)	45
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	44
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	44
Bacterial keratitis: identifying the areas of clinical uncertainty	43
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	42
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	41
Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases	40
Clinical histopathology and pathogenesis of macular telangiectasia type 2	39
Artificial intelligence in ophthalmology: Progress, challenges, and ethical implications	39
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	38
Prospects for the application of Müller glia and their derivatives in retinal regenerative therapies	37
Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies,	37
Tilted disc syndrome (TDS): New hypotheses for posterior segment complications and their implications in other retinal diseases	36
The relationship between intraocular pressure and glaucoma: An evolving concept	36
Eye on the horizon: The metabolic landscape of the RPE in aging and disease	35
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation	35
Zebrafish and inherited photoreceptor disease: Models and insights	34
Editorial Board	34
The multifunctional human ocular melanocortin system	33
Decoding pediatric inherited retinal dystrophies: Bridging genetic complexity and clinical heterogeneity	32
Familial normal tension glaucoma genetics	31

Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy	30
Potential therapeutic targets for age-related macular degeneration: The nuclear option	29
Value proposition of retinal imaging in Alzheimer's disease screening: A review of eight evolving trends	29
Healing the cornea: Exploring the therapeutic solutions offered by MSCs and MSC-derived EVs	29
The dark and bright sides of retinal G protein-coupled receptor (RGR) in vision and disease	29
Syndromic retinitis pigmentosa	29
Müller cells and astrocytes in tractional macular disorders	28
Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms	27
Characterizing Bruch's membrane: State-of-the-art imaging, computational segmentation, and biologic models in retinal disease and health	27
Corrigendum to “Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease” [Progr. Retin. Eye Res. 106 (2025) 101362]	27
Translation of single-cell transcriptomic analysis of uveal melanomas to clinical oncology	27
A reinterpretation of critical flicker-frequency (CFF) data reveals key details about light adaptation and normal and abnormal visual processing	26
Editorial Board	26
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy	26
Cellular and subcellular optogenetic approaches towards neuroprotection and vision restoration	25
The two-faced effects of nerves and neuropeptides in corneal diseases	24
Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease	23
Imaging of the retinal hypoxia: A journey from oxygen microelectrode to the first hypoxia imaging in the living retina	23
Pericytes in the optic nerve head	22
Latest advances in white spot syndromes: New findings and interpretations	22
The versatile roles of retinal pigment epithelium in the pathophysiology of retinitis pigmentosa	22
Editorial Board	22
The AI revolution in glaucoma: Bridging challenges with opportunities	22
Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice	21
Editorial Board	21
Ocular manifestations of COVID-19	21
Age and intraocular pressure in murine experimental glaucoma	21
The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: More than cellular clean up	20
Müller cells trophism and pathology as the next therapeutic targets for retinal diseases	20
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation	20
Optical coherence tomography in the management of diabetic macular oedema	19
Eyelid dermatitis: Work-up and future diagnostic innovative solutions	19
Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration	19
Advances in understanding the molecular structure of retinoschisin while questions remain of biological function	19
Shining light on CRISPR/Cas9 therapeutics for inherited retinal diseases	19
In vitro and ex vivo models of microbial keratitis: Present and future	18
Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications	17
Corrigendum to “Splicing mutations in inherited retinal diseases” [Prog. Retin. Eye Res. 80 (2021) 100874]	17
Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches	16
The physiology of dark adaptation: Progress and future directions	16
Zinc in eye health, retinal biology and disease	16
Artificial intelligence in OCT angiography	15
Bisretinoid lipofuscin, fundus autofluorescence and retinal disease	15
Comparative insights into the role of sex hormones in glaucoma among women and men	15
Therapy with voretigene neparvovec. How to measure success?	15
Safety and effectiveness of vital dyes for intraocular surgery	15
Eyes shut homolog (EYS): Connecting molecule to disease	15
The role of the gut microbiome in eye diseases	14
Inherited retinal diseases: Linking genes, disease-causing variants, and relevant therapeutic modalities	14
Diabetic macular ischaemia- a new therapeutic target?	14
Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy	14