OOIR: Observatory of International Research

Papers

(The median citation count of Progress in Retinal and Eye Research is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
The neuroimmune interface in retinal regeneration	196
In vivo application of base and prime editing to treat inherited retinal diseases	179
Widefield OCT angiography	178
Cell identity changes in ocular surface Epithelia	159
Vogt-Koyanagi-Harada disease under the lens: Insights from multimodal ocular imaging	145
Non-vasogenic cystoid maculopathies	145
International consensuses and controversies on causes, diagnosis and management of diabetic macular edema (DME)	136
Phenotyping and genotyping FEVR: Molecular genetics, clinical and imaging features, and therapeutics	121
Animal models for the evaluation of retinal stem cell therapies	118
Editorial Board	110
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas	109
Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation	108
Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	101
Unravelling CYP4V2: Clinical features, genetic insights, pathogenic mechanisms and therapeutic strategies in Bietti crystalline corneoretinal dystrophy	95
Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration	92
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	91
Central serous chorioretinopathy: An evidence-based treatment guideline	89
Corneal stromal repair and regeneration	87
Editorial Board	84
A paradigm shift in retinal detachment repair: The concept of integrity	84
Myocilin misfolding and glaucoma: A 20-year update	84
Squishy matters – Corneal mechanobiology in health and disease	82
Homeostatic plasticity in the retina	80
Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)	78
Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors	78

Quantification of retinal microvascular imaging features from fundus photos in ocular and systemic disease: a framework for standardization	75
Risk factors, clinical features and treatment of Behçet's disease uveitis	74
Are Müller glial cells gatekeepers of neuroprotection and regeneration in age-related macular degeneration? Unraveling their roles in pathophysiology and therapeutic innovation	71
The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease	71
Cell fate decisions, transcription factors and signaling during early retinal development	70
How gut microbiota may impact ocular surface homeostasis and related disorders	69
Femtosecond lasers in ophthalmology: Mechanisms, clinical breakthroughs, and multidisciplinary frontiers	69
The retinal pigmentation pathway in human albinism: Not so black and white	65
Eye care adherence in pediatric and elderly: Understanding and addressing the challenges	64
RNA-targeting strategies as a platform for ocular gene therapy	63
Genetic architecture of congenital cataracts: correlation of pathogenic variants with morphology and clinical outcomes	60
Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration	59
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	57
Cellular component transfer between photoreceptor cells of the retina	57
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	56
Rhodopsin, light-sensor of vision	56
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	52
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	50
Editorial Board	49
Optical coherence tomography angiography in diabetic retinopathy	49
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	47
Regulation of lens water content: Effects on the physiological optics of the lens	47
Pentosan polysulfate maculopathy: clinical considerations, pathobiology, and causality	47
Outer retinal tubulation associated with photoreceptor degeneration	46
Beyond convolutions and supervised learning with transformers and representation learning for retinal image analysis	45
Interventions to reduce incidence and progression of myopia in children and adults	44
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	42
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	42
Quantitative analysis of conjunctival vascular alterations: Applications in ocular and systemic disease detection	41
Editorial Board	41
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	40
The march to harmonized imaging standards for retinal imaging	39
Bacterial keratitis: identifying the areas of clinical uncertainty	38
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	37
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	37
Editorial Board	37
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	36
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	36
The ocular surface in type 2 diabetes: pathophysiology and impact of anti-diabetic drugs	35
Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases	35
Artificial intelligence in ophthalmology: Progress, challenges, and ethical implications	34
Clinical histopathology and pathogenesis of macular telangiectasia type 2	33
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	33
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation	32
Minimally invasive glaucoma surgery in the surgical landscape of primary angle closure glaucoma: Current innovations and future trends	32
The relationship between intraocular pressure and glaucoma: An evolving concept	32
Eye on the horizon: The metabolic landscape of the RPE in aging and disease	31
Potential therapeutic targets for age-related macular degeneration: The nuclear option	30
Decoding pediatric inherited retinal dystrophies: Bridging genetic complexity and clinical heterogeneity	30
Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies,	30

Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy	29
The multifunctional human ocular melanocortin system	28
Value proposition of retinal imaging in Alzheimer's disease screening: A review of eight evolving trends	28
Familial normal tension glaucoma genetics	27
The dark and bright sides of retinal G protein-coupled receptor (RGR) in vision and disease	27
Glymphatic transport and ocular diseases	26
Polygenic risk scores for glaucoma: Impact on diagnosis and disease course	26
Healing the cornea: Exploring the therapeutic solutions offered by MSCs and MSC-derived EVs	26
Aging, oxidative stress, and cataracts: Therapeutic prospects and translational insights into peroxiredoxin 6	25
Characterizing Bruch's membrane: State-of-the-art imaging, computational segmentation, and biologic models in retinal disease and health	25
Zebrafish and inherited photoreceptor disease: Models and insights	25
Corrigendum to “Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease” [Progr. Retin. Eye Res. 106 (2025) 101362]	25
Syndromic retinitis pigmentosa	25
Imaging of the retinal hypoxia: A journey from oxygen microelectrode to the first hypoxia imaging in the living retina	24
Structural photoreceptor evaluation in age-related macular degeneration. A comprehensive review of methods and clinical significance	23
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy	23
Eye–brain axis: Ocular and visual pathophysiology as driver and therapeutic target across the mood disorder trajectory	23
Cellular and subcellular optogenetic approaches towards neuroprotection and vision restoration	23
Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms	23
Editorial Board	23
The AI revolution in glaucoma: Bridging challenges with opportunities	22
Latest advances in white spot syndromes: New findings and interpretations	22
The versatile roles of retinal pigment epithelium in the pathophysiology of retinitis pigmentosa	20
Ocular gene therapy mediated by AAV vectors: an overview of immunosuppressive treatments and immunomonitoring of patients involved in clinical trials	20
Pericytes in the optic nerve head	19
Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice	18
Retinal vessel imaging in inflammatory disease: From endothelial dysfunction to clinical evidence and translation	18
Editorial Board	18
Ocular manifestations of COVID-19	18
Eyelid dermatitis: Work-up and future diagnostic innovative solutions	18
Advances in understanding the molecular structure of retinoschisin while questions remain of biological function	17
The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: More than cellular clean up	17
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation	17
Shining light on CRISPR/Cas9 therapeutics for inherited retinal diseases	17
Müller cells trophism and pathology as the next therapeutic targets for retinal diseases	17
Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration	16
In vitro and ex vivo models of microbial keratitis: Present and future	16
Optical coherence tomography in the management of diabetic macular oedema	16
Safety and effectiveness of vital dyes for intraocular surgery	15
Eyes shut homolog (EYS): Connecting molecule to disease	15
Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications	15
Comparative insights into the role of sex hormones in glaucoma among women and men	14
The physiology of dark adaptation: Progress and future directions	14
Zinc in eye health, retinal biology and disease	13
Bisretinoid lipofuscin, fundus autofluorescence and retinal disease	13
Therapy with voretigene neparvovec. How to measure success?	13
Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy	12
Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches	12
Unsolved retinal questions	11
AI in the clinical management of GA: A novel therapeutic universe requires novel tools	11
Corrigendum to “Widefield OCT angiography” [Progress in Retinal and Eye Research. 107 (2025) 101378]	11
IOP and glaucoma damage: The essential role of optic nerve head and retinal mechanosensors	11
Diabetic macular ischaemia- a new therapeutic target?	11
Editorial Board	11
Editorial Board	11
Inherited retinal diseases: Linking genes, disease-causing variants, and relevant therapeutic modalities	11
The role of the gut microbiome in eye diseases	11
Toward an internationally accepted standard for reading charts	11