Cell Death and Differentiation

Papers
(The median citation count of Cell Death and Differentiation is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Regulating GSDMB pore formation: to ignite or inhibit?519
Transglutaminase 2 crosslinks zona pellucida glycoprotein 3 to prevent polyspermy373
PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions339
Bridging tissue repair and epithelial carcinogenesis: epigenetic memory and field cancerization281
The m6A methyltransferase METTL3 drives neuroinflammation and neurotoxicity through stabilizing BATF mRNA in microglia261
AMDHD1 acts as a tumor suppressor and contributes to activation of TGF-β signaling pathway in cholangiocarcinoma214
Age-related p53 SUMOylation accelerates senescence and tau pathology in Alzheimer’s disease203
Lactylation of NAT10 promotes N4‐acetylcytidine modification on tRNASer-CGA-1-1 to boost oncogenic DNA virus KSHV reactivation193
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response179
FBXL4 mutations cause excessive mitophagy via BNIP3/BNIP3L accumulation leading to mitochondrial DNA depletion syndrome163
Past, present, and future perspectives of transcription factor EB (TFEB): mechanisms of regulation and association with disease154
Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a141
Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy140
The Smad4-MYO18A-PP1A complex regulates β-catenin phosphorylation and pemigatinib resistance by inhibiting PAK1 in cholangiocarcinoma131
OPA1 drives macrophage metabolism and functional commitment via p65 signaling130
Targeting adipocytic discoidin domain receptor 2 impedes fat gain while increasing bone mass125
Repression of p53 function by SIRT5-mediated desuccinylation at Lysine 120 in response to DNA damage121
The regulation loop of MARVELD1 interacting with PARP1 in DNA damage response maintains genome stability and promotes therapy resistance of cancer cells117
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease113
MTGR1 is required to maintain small intestinal stem cell populations108
BAP1 shapes the bone marrow niche for lymphopoiesis by fine-tuning epigenetic profiles in endosteal mesenchymal stromal cells106
Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster106
TFEB controls syncytiotrophoblast formation and hormone production in placenta104
Vps34 sustains Treg cell survival and function via regulating intracellular redox homeostasis104
The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy101
Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis98
Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development97
Mechanisms controlling plant proteases and their substrates97
Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis90
Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke86
Ssu72-HNF4α signaling axis classify the transition from steatohepatitis to hepatocellular carcinoma86
Caspase-2 does not play a critical role in cell death induction and bacterial clearance during Salmonella infection86
SCML2 contributes to tumor cell resistance to DNA damage through regulating p53 and CHK1 stability81
The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection80
A CVID-associated variant in the ciliogenesis protein CCDC28B disrupts immune synapse assembly79
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution78
YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer78
E3 ligase RNF99 negatively regulates TLR-mediated inflammatory immune response via K48-linked ubiquitination of TAB277
PARsylated transcription factor EB (TFEB) regulates the expression of a subset of Wnt target genes by forming a complex with β-catenin-TCF/LEF175
Sirt3 mediates the benefits of exercise on bone in aged mice75
A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival72
Role of Fra-2 in cancer71
The scramblases VMP1 and TMEM41B are required for primitive endoderm specification by targeting WNT signaling70
Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state68
Temporal dissection of the roles of Atg4 and ESCRT in autophagosome formation in yeast68
LncRNA NEAT1 controls the lineage fates of BMSCs during skeletal aging by impairing mitochondrial function and pluripotency maintenance67
The osteoprotective role of USP26 in coordinating bone formation and resorption63
Patients with COVID-19: in the dark-NETs of neutrophils62
DCC/netrin-1 regulates cell death in oligodendrocytes after brain injury59
APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy59
JAM-ming miR-2158
Anastasis confers ovarian cancer cells increased malignancy through elevated p38 MAPK activation58
NKAP acts with HDAC3 to prevent R-loop associated genome instability57
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies55
Targeting HDAC3 to overcome the resistance to ATRA or arsenic in acute promyelocytic leukemia through ubiquitination and degradation of PML-RARα54
Long Covid: where we stand and challenges ahead51
RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation51
Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt–β-catenin–STAT3 signaling50
Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation49
Histone H2Bub1 deubiquitylation is essential for mouse development, but does not regulate global RNA polymerase II transcription49
LncRNA LY6E-DT and its encoded metastatic-related protein play oncogenic roles via different pathways and promote breast cancer progression49
DNA-PKcs regulates myogenesis in an Akt-dependent manner independent of induced DNA damage48
Coordination between cell proliferation and apoptosis after DNA damage in Drosophila48
Opposing functions of β-arrestin 1 and 2 in Parkinson’s disease via microglia inflammation and Nprl348
USP2 promotes tumor immune evasion via deubiquitination and stabilization of PD-L147
FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system47
A novel MYC-ZNF706-SLC7A11 regulatory circuit contributes to cancer progression and redox balance in human hepatocellular carcinoma46
Atg7 autophagy-independent role on governing neural stem cell fate could be potentially applied for regenerative medicine46
The biophysical property of the limbal niche maintains stemness through YAP45
Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation44
Sirtuin 4 activates autophagy and inhibits tumorigenesis by upregulating the p53 signaling pathway44
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis43
HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer42
TRIM3 facilitates ferroptosis in non-small cell lung cancer through promoting SLC7A11/xCT K11-linked ubiquitination and degradation42
Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis41
Dying in self-defence: a comparative overview of immunogenic cell death signalling in animals and plants41
Hornerin mediates phosphorylation of the polo-box domain in Plk1 by Chk1 to induce death in mitosis40
Apoptotic cell death in disease—Current understanding of the NCCD 202340
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment39
Should mutant TP53 be targeted for cancer therapy?39
Sensing of mitochondrial DNA by ZBP1 promotes RIPK3-mediated necroptosis and ferroptosis in response to diquat poisoning39
The caspase-6–p62 axis modulates p62 droplets based autophagy in a dominant-negative manner38
Externalized phosphatidylinositides on apoptotic cells are eat-me signals recognized by CD1438
Apoptotic caspase-7 activation inhibits non-canonical pyroptosis by GSDMB cleavage38
Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak38
RhoA signaling increases mitophagy and protects cardiomyocytes against ischemia by stabilizing PINK1 protein and recruiting Parkin to mitochondria37
Unveiling the methionine cycle: a key metabolic signature and NR4A2 as a methionine-responsive oncogene in esophageal squamous cell carcinoma37
A self-amplifying USP14-TAZ loop drives the progression and liver metastasis of pancreatic ductal adenocarcinoma37
Telomerase deficiency and dysfunctional telomeres in the lung tumor microenvironment impair tumor progression in NSCLC mouse models and patient-derived xenografts36
Circadian rhythm modulates endochondral bone formation via MTR1/AMPKβ1/BMAL1 signaling axis35
Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis35
The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson’s disease35
Deubiquitination of MYC by OTUB1 contributes to HK2 mediated glycolysis and breast tumorigenesis34
SNORD88C guided 2′-O-methylation of 28S rRNA regulates SCD1 translation to inhibit autophagy and promote growth and metastasis in non-small cell lung cancer33
Non-coding RNAs and ferroptosis: potential implications for cancer therapy33
Cuproptosis: p53-regulated metabolic cell death?33
NAT10 regulates mitotic cell fate by acetylating Eg5 to control bipolar spindle assembly and chromosome segregation33
O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGγ interaction33
Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis33
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation33
Targeting the miR-34a/LRPPRC/MDR1 axis collapse the chemoresistance in P53 inactive colorectal cancer32
The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF132
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A32
PHGDH/SYK: a hub integrating anti-fungal immunity and serine metabolism32
Correction to: DC-SIGN–LEF1/TCF1–miR-185 feedback loop promotes colorectal cancer invasion and metastasis31
Correction to: LncRNA H19 initiates microglial pyroptosis and neuronal death in retinal ischemia/reperfusion injury31
Correction to: Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection31
Correction: Ubiquitin B: an essential mediator of trichostatin A-induced tumor-selective killing in human cancer cells31
Correction: OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation31
Correction: EGFR inhibits TNF-α-mediated pathway by phosphorylating TNFR1 at tyrosine 360 and 40131
Correction to: The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells30
N6-methyladenosine-modified USP13 induces pro-survival autophagy and imatinib resistance via regulating the stabilization of autophagy-related protein 5 in gastrointestinal stromal tumors29
Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer29
MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF29
OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation29
John F. R. Kerr (1934–2024)29
A novel hypoxia-induced lncRNA, SZT2-AS1, boosts HCC progression by mediating HIF heterodimerization and histone trimethylation under a hypoxic microenvironment29
HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB229
Metabolic adaptation to hypoxia: do worms and cancer cells share common metabolic responses to hypoxic stress?28
Doublecortin-like kinase 1 activates NF-κB to induce inflammatory responses by binding directly to IKKβ28
Correction to: RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development28
Bromodomain protein BRDT directs ΔNp63 function and super-enhancer activity in a subset of esophageal squamous cell carcinomas28
NUMB facilitates autophagy initiation through targeting SCFβ-TrCP2 complex28
Retraction Note to: Glucose-6-phosphate dehydrogenase plays a crucial role in protection from redox-stress-induced apoptosis28
Determinants of p53 DNA binding, gene regulation, and cell fate decisions28
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice28
ABLIM1, a novel ubiquitin E3 ligase, promotes growth and metastasis of colorectal cancer through targeting IĸBα ubiquitination and activating NF-ĸB signaling27
MafG/MYH9-LCN2 axis promotes liver fibrosis through inhibiting ferroptosis of hepatic stellate cells27
Natural selection at the cellular level: insights from male germ cell differentiation27
CD63 acts as a functional marker in maintaining hematopoietic stem cell quiescence through supporting TGFβ signaling in mice27
RNA-interference screen for p53 regulators unveils a role of WDR75 in ribosome biogenesis27
A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy27
Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3tm1Flv mice26
Correction to: Build-UPS and break-downs: metabolism impacts on proteostasis and aging26
Correction to: Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis26
Correction: Global deletion of optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget’s disease26
Correction: PLK1/vimentin signaling facilitates immune escape by recruiting Smad2/3 to PD-L1 promoter in metastatic lung adenocarcinoma26
Correction to: M6A RNA methylation-mediated RMRP stability renders proliferation and progression of non-small cell lung cancer through regulating TGFBR1/SMAD2/SMAD3 pathway26
Zeb1-controlled metabolic plasticity enables remodeling of chromatin accessibility in the development of neuroendocrine prostate cancer26
Mutant p53 reactivation restricts the protumorigenic consequences of wild type p53 loss of heterozygosity in Li-Fraumeni syndrome patient-derived fibroblasts25
Caspase cleavage of RIPK3 after Asp333 is dispensable for mouse embryogenesis25
Disrupting CCDC137-mediated LZTS2 and β-TrCP interaction in the nucleus inhibits hepatocellular carcinoma development via β-catenin and AKT25
SLC15A3 plays a crucial role in pulmonary fibrosis by regulating macrophage oxidative stress25
Activated KRAS, polyamines, iASPP and TME: a multiple liaison in pancreatic cancer25
Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone25
MLKL post-translational modifications: road signs to infection, inflammation and unknown destinations25
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics24
The birth of death, 30 years ago24
Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer24
Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia24
BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells24
Set7/9 aggravates ischemic brain injury via enhancing glutamine metabolism in a blocking Sirt5 manner24
Mechanisms of regulated cell death during plant infection by the rice blast fungus Magnaporthe oryzae24
Upregulation of Wilms’ Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice24
A comprehensive interaction study provides a potential domain interaction network of human death domain superfamily proteins24
OTUD5 promotes the inflammatory immune response by enhancing MyD88 oligomerization and Myddosome formation23
Comorbidity-associated glutamine deficiency is a predisposition to severe COVID-1923
CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14ARF degradation23
Surviving the host–pathogen interaction: Legionella uses its SidE arsenal to mediate phosphoribosyl-linked ubiquitination of Golgi proteins inducing organelle fragmentation23
Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET23
Epithelial de-differentiation triggered by co-ordinate epigenetic inactivation of the EHF and CDX1 transcription factors drives colorectal cancer progression23
The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle23
The BCL2 inhibitor venetoclax mediates anticancer effects through dendritic cell activation23
A BAK subdomain that binds mitochondrial lipids selectively and releases cytochrome C23
The bone–liver interaction modulates immune and hematopoietic function through Pinch-Cxcl12-Mbl2 pathway22
Oxoglutarate dehydrogenase-like inhibits the progression of hepatocellular carcinoma by inducing DNA damage through non-canonical function22
H3K27me3 timely dictates uterine epithelial transcriptome remodeling and thus transformation essential for normal embryo implantation22
The Hippo signaling component LATS2 enhances innate immunity to inhibit HIV-1 infection through PQBP1-cGAS pathway22
Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development22
Ferroptosis-based advanced therapies as treatment approaches for metabolic and cardiovascular diseases21
USP24 promotes drug resistance during cancer therapy21
Myeloid Mir34a suppresses colitis-associated colon cancer: characterization of mediators by single-cell RNA sequencing21
Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence21
Editorial Expression of Concern: The NAD+ salvage pathway modulates cancer cell viability via p7321
MNT suppresses T cell apoptosis via BIM and is critical for T lymphomagenesis21
Fructose: the sweet(er) side of the Warburg effect21
Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent21
The role(s) of NF-Y in development and differentiation20
The AKR1C1–CYP1B1–cAMP signaling axis controls tumorigenicity and ferroptosis susceptibility of extrahepatic cholangiocarcinoma20
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs20
The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein20
Deubiquitinase USP7 stabilizes KDM5B and promotes tumor progression and cisplatin resistance in nasopharyngeal carcinoma through the ZBTB16/TOP2A axis20
The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine20
The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway20
Selective autophagy controls the stability of TBK1 via NEDD4 to balance host defense20
A chromosome-coupled ubiquitin-proteasome pathway is required for meiotic surveillance19
USP42 drives nuclear speckle mRNA splicing via directing dynamic phase separation to promote tumorigenesis19
O-GlcNAcylation of MORC2 at threonine 556 by OGT couples TGF-β signaling to breast cancer progression19
miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin119
SENP2-PLCβ4 signaling regulates neurogenesis through the maintenance of calcium homeostasis19
Correction: Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease19
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer19
CBFβ promotes colorectal cancer progression through transcriptionally activating OPN, FAM129A, and UPP1 in a RUNX2-dependent manner19
Activation of Drp1 promotes fatty acids-induced metabolic reprograming to potentiate Wnt signaling in colon cancer18
Dural Tregs driven by astrocytic IL-33 mitigate depression through the EGFR signals in mPFC neurons18
EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma18
The circRNA CNEACR regulates necroptosis of cardiomyocytes through Foxa2 suppression18
HSP90β promotes osteoclastogenesis by dual-activation of cholesterol synthesis and NF-κB signaling18
Angiopoietin-like protein 8 directs DNA damage responses towards apoptosis by stabilizing PARP1-DNA condensates18
USP11 regulates autophagy-dependent ferroptosis after spinal cord ischemia-reperfusion injury by deubiquitinating Beclin 118
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis18
MS4A15 drives ferroptosis resistance through calcium-restricted lipid remodeling18
Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence18
SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis17
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma17
AMPKα loss promotes KRAS-mediated lung tumorigenesis17
Ubiquitin ligase E3 HUWE1/MULE targets transferrin receptor for degradation and suppresses ferroptosis in acute liver injury17
QSER1 preserves the suppressive status of the pro-apoptotic genes to prevent apoptosis17
MBD2 acts as a repressor to maintain the homeostasis of the Th1 program in type 1 diabetes by regulating the STAT1-IFN-γ axis17
YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect17
PPA1 promotes adipogenesis by regulating the stability of C/EBPs17
Deubiquitinase OTUD6A promotes breast cancer progression by increasing TopBP1 stability and rendering tumor cells resistant to DNA-damaging therapy16
Mapping the hotspots for DNA repair synthesis in human brain organoids16
YTHDC1 as a tumor progression suppressor through modulating FSP1-dependent ferroptosis suppression in lung cancer16
Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species16
Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10−/− model of colitis16
Cold-inducible RNA binding protein alleviates iron overload-induced neural ferroptosis under perinatal hypoxia insult16
LUBAC enables tumor-promoting LTβ receptor signaling by activating canonical NF-κB16
Correction to: HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation16
BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer16
USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer16
Targeting mitochondrial metabolism for precision medicine in cancer16
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis16
The power of an idea: Andrew Wyllie16
Epiblast fragmentation by shedding—a novel mechanism to eliminate cells in post-implantation mouse embryos15
CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma15
Mitochondrial RNA methyltransferase TRMT61B is a new, potential biomarker and therapeutic target for highly aneuploid cancers15
IKBKE phosphorylates and stabilizes Snail to promote breast cancer invasion and metastasis15
Retraction Note: Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 through the increase15
Endogenous BAX and BAK form mosaic rings of variable size and composition on apoptotic mitochondria15
Loss of Fbxo45 in AT2 cells leads to insufficient histone supply and initiates lung adenocarcinoma15
FBXL6 degrades phosphorylated p53 to promote tumor growth15
MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm14
AF9 targets acetyl-modified STAT6 to diminish purine metabolism and accelerate cell apoptosis during metastasis14
BCL-G: 20 years of research on a non-typical protein from the BCL-2 family14
Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress14
Epitranscriptomic modifications in mesenchymal stem cell differentiation: advances, mechanistic insights, and beyond14
Snail/PRMT5/NuRD complex contributes to DNA hypermethylation in cervical cancer by TET1 inhibition14
The OGT–c-Myc–PDK2 axis rewires the TCA cycle and promotes colorectal tumor growth14
Brain-specific Pd1 deficiency leads to cortical neurogenesis defects and depressive-like behaviors in mice14
AMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell death14
Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-114
Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD5114
Inhibition of BAK-mediated apoptosis by the BH3-only protein BNIP513
CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway13
Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment13
B7-1 mediates podocyte injury and glomerulosclerosis through communication with Hsp90ab1-LRP5-β-catenin pathway13
Sustained intracellular calcium rise mediates neuronal mitophagy in models of autosomal dominant optic atrophy13
Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection13
Rewiring cancer cell death: LPCAT1 shapes lipid composition and ferroptosis resistance13
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