OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death and Differentiation is 54. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Regulating GSDMB pore formation: to ignite or inhibit?	519
Transglutaminase 2 crosslinks zona pellucida glycoprotein 3 to prevent polyspermy	373
PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions	339
Bridging tissue repair and epithelial carcinogenesis: epigenetic memory and field cancerization	281
The m6A methyltransferase METTL3 drives neuroinflammation and neurotoxicity through stabilizing BATF mRNA in microglia	261
AMDHD1 acts as a tumor suppressor and contributes to activation of TGF-β signaling pathway in cholangiocarcinoma	214
Age-related p53 SUMOylation accelerates senescence and tau pathology in Alzheimer’s disease	203
Lactylation of NAT10 promotes N4‐acetylcytidine modification on tRNASer-CGA-1-1 to boost oncogenic DNA virus KSHV reactivation	193
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response	179
FBXL4 mutations cause excessive mitophagy via BNIP3/BNIP3L accumulation leading to mitochondrial DNA depletion syndrome	163
Past, present, and future perspectives of transcription factor EB (TFEB): mechanisms of regulation and association with disease	154
Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a	141
Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy	140
The Smad4-MYO18A-PP1A complex regulates β-catenin phosphorylation and pemigatinib resistance by inhibiting PAK1 in cholangiocarcinoma	131
OPA1 drives macrophage metabolism and functional commitment via p65 signaling	130
Targeting adipocytic discoidin domain receptor 2 impedes fat gain while increasing bone mass	125
Repression of p53 function by SIRT5-mediated desuccinylation at Lysine 120 in response to DNA damage	121
The regulation loop of MARVELD1 interacting with PARP1 in DNA damage response maintains genome stability and promotes therapy resistance of cancer cells	117
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease	113
MTGR1 is required to maintain small intestinal stem cell populations	108
Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster	106
BAP1 shapes the bone marrow niche for lymphopoiesis by fine-tuning epigenetic profiles in endosteal mesenchymal stromal cells	106
TFEB controls syncytiotrophoblast formation and hormone production in placenta	104
Vps34 sustains Treg cell survival and function via regulating intracellular redox homeostasis	104
The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy	101

Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis	98
Mechanisms controlling plant proteases and their substrates	97
Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development	97
Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis	90
Caspase-2 does not play a critical role in cell death induction and bacterial clearance during Salmonella infection	86
Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke	86
Ssu72-HNF4α signaling axis classify the transition from steatohepatitis to hepatocellular carcinoma	86
SCML2 contributes to tumor cell resistance to DNA damage through regulating p53 and CHK1 stability	81
The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection	80
A CVID-associated variant in the ciliogenesis protein CCDC28B disrupts immune synapse assembly	79
YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer	78
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution	78
E3 ligase RNF99 negatively regulates TLR-mediated inflammatory immune response via K48-linked ubiquitination of TAB2	77
PARsylated transcription factor EB (TFEB) regulates the expression of a subset of Wnt target genes by forming a complex with β-catenin-TCF/LEF1	75
Sirt3 mediates the benefits of exercise on bone in aged mice	75
A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival	72
Role of Fra-2 in cancer	71
The scramblases VMP1 and TMEM41B are required for primitive endoderm specification by targeting WNT signaling	70
Temporal dissection of the roles of Atg4 and ESCRT in autophagosome formation in yeast	68
Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state	68
LncRNA NEAT1 controls the lineage fates of BMSCs during skeletal aging by impairing mitochondrial function and pluripotency maintenance	67
The osteoprotective role of USP26 in coordinating bone formation and resorption	63
Patients with COVID-19: in the dark-NETs of neutrophils	62
DCC/netrin-1 regulates cell death in oligodendrocytes after brain injury	59
APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy	59
Anastasis confers ovarian cancer cells increased malignancy through elevated p38 MAPK activation	58
JAM-ming miR-21	58
NKAP acts with HDAC3 to prevent R-loop associated genome instability	57
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies	55
Targeting HDAC3 to overcome the resistance to ATRA or arsenic in acute promyelocytic leukemia through ubiquitination and degradation of PML-RARα	54