OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death and Differentiation is 59. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2	938
Retraction Note to: Glucose-6-phosphate dehydrogenase plays a crucial role in protection from redox-stress-induced apoptosis	530
NAT10 regulates mitotic cell fate by acetylating Eg5 to control bipolar spindle assembly and chromosome segregation	439
Non-pyroptotic caspase-11 activity regulates osteoclastogenesis and pathological bone loss	352
TRIM11 potentiates antitumor immunity via inhibition of the IFN-γ/PD-L1 axis	335
PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions	300
Age-related p53 SUMOylation accelerates senescence and tau pathology in Alzheimer’s disease	292
Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development	283
HERP constrains white adipose expansion and inflammation by STEAP4 stabilization	245
Long Covid: where we stand and challenges ahead	245
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease	238
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response	218
Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis	195
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment	183
The scramblases VMP1 and TMEM41B are required for primitive endoderm specification by targeting WNT signaling	160
A novel hypoxia-induced lncRNA, SZT2-AS1, boosts HCC progression by mediating HIF heterodimerization and histone trimethylation under a hypoxic microenvironment	153
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A	151
USP2 promotes tumor immune evasion via deubiquitination and stabilization of PD-L1	148
NKAP acts with HDAC3 to prevent R-loop associated genome instability	144
The birth of death, 30 years ago	136
Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activato	132
Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent	124
miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1	123
USP38 functions as an oncoprotein by downregulating the p53 pathway through deubiquitination and stabilization of MDM2	122
Disrupting CCDC137-mediated LZTS2 and β-TrCP interaction in the nucleus inhibits hepatocellular carcinoma development via β-catenin and AKT	121

KRAS mutation increases histone H3 lysine 9 lactylation (H3K9la) to promote colorectal cancer progression by facilitating cholesterol transporter GRAMD1A expression	120
The bone–liver interaction modulates immune and hematopoietic function through Pinch-Cxcl12-Mbl2 pathway	117
USP13 depletion sensitizes colorectal cancer cells to necroptosis by destabilizing cIAP2 proteins	116
Uridine 5’-monophosphate (UMP) synthesis connects nucleotide metabolism to programmed cell death in C. elegans	115
Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics	113
Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development	112
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs	107
Targeting MMA-induced USP36 methylmalonylation to suppress macrophage polarization and tumor progression in clear-cell renal cell carcinoma	104
A chromosome-coupled ubiquitin-proteasome pathway is required for meiotic surveillance	103
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer	94
MLKL post-translational modifications: road signs to infection, inflammation and unknown destinations	85
The USP43/RNF2 axis negatively regulates antiviral innate immunity by promoting TBK1 ubiquitination and degradation	83
Daniel Aberdam, the legacy of a mentor	81
Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-1	80
Dying in self-defense: cell death signaling in animals and plants	77
Aberrant activation of p53/p66Shc-mInsc axis increases asymmetric divisions and attenuates proliferation of aged mammary stem cells	75
Correction: NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells	74
Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions	72
Correction: The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis	71
CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity	71
AF9 targets acetyl-modified STAT6 to diminish purine metabolism and accelerate cell apoptosis during metastasis	70
Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor	70
DDHD2, whose mutations cause spastic paraplegia type 54, enhances lipophagy via engaging ATG8 family proteins	70
A viral interferon regulatory factor degrades RNA-binding protein hnRNP Q1 to enhance aerobic glycolysis via recruiting E3 ubiquitin ligase KLHL3 and decaying GDPD1 mRNA	68
TIN2 modulates FOXO1 mitochondrial shuttling to enhance oxidative stress-induced apoptosis in retinal pigment epithelium under hyperglycemia	68
NEDD4L-mediated Gasdermin D and E ubiquitination regulates cell death and tissue injury	67
Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress	66
Targeting N-glycosylation of 4F2hc mediated by glycosyltransferase B3GNT3 sensitizes ferroptosis of pancreatic ductal adenocarcinoma	65
Chromosomal 3p loss and 8q gain drive vasculogenic mimicry via HIF-2α and VE-cadherin activation in uveal melanoma	65
Post-transcriptional dynamics and RNA homeostasis in autophagy and cancer	62
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer	60
Targeting necroptosis prevents viral-induced lung damage	60
SIRT5-mediated ME2 desuccinylation promotes cancer growth by enhancing mitochondrial respiration	59
USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer	59