OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death and Differentiation is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
FAM96A functions as a novel pace controller for iron uptake to maintain iron homeostasis and erythropoiesis	429
Gut-derived hyodeoxycholate reprograms the spleen–eye immunometabolic axis to suppress autoimmune uveitis	390
Non-pyroptotic caspase-11 activity regulates osteoclastogenesis and pathological bone loss	358
Retraction Note to: Glucose-6-phosphate dehydrogenase plays a crucial role in protection from redox-stress-induced apoptosis	277
The scramblases VMP1 and TMEM41B are required for primitive endoderm specification by targeting WNT signaling	265
TRIM11 potentiates antitumor immunity via inhibition of the IFN-γ/PD-L1 axis	249
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response	183
The E3 ubiquitin ligase Itch plays an essential role in kidney fibrosis by inhibiting Dvl2/GSK3β/β-catenin signaling pathway	178
Long Covid: where we stand and challenges ahead	161
HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2	151
PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions	149
SETD7 depletion enhances white adipose browning and ameliorates metabolic disorders in obese mice	147
NKAP acts with HDAC3 to prevent R-loop associated genome instability	128
Correction: Epigenetic restriction of Hippo signaling by MORC2 underlies stemness of hepatocellular carcinoma cells	128
HECT ubiquitin ligases as regulators of inflammatory signalling	127
GPS2 regulates embryonic angiogenesis by enhancing endothelial cell survival through stabilizing HOIP	104
USP2 promotes tumor immune evasion via deubiquitination and stabilization of PD-L1	102
AURKA regulates LGR5 in response to Helicobacter Pylori infection by modulating its deubiquitination	101
Age-related p53 SUMOylation accelerates senescence and tau pathology in Alzheimer’s disease	96
Ribosome stress meets disulfidptosis: HOIL-1 safeguards cell fate during nutrient deprivation	90
A novel hypoxia-induced lncRNA, SZT2-AS1, boosts HCC progression by mediating HIF heterodimerization and histone trimethylation under a hypoxic microenvironment	88
HERP constrains white adipose expansion and inflammation by STEAP4 stabilization	83
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment	82
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A	82
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease	82

Uridine 5’-monophosphate (UMP) synthesis connects nucleotide metabolism to programmed cell death in C. elegans	81
USP38 functions as an oncoprotein by downregulating the p53 pathway through deubiquitination and stabilization of MDM2	80
USP13 depletion sensitizes colorectal cancer cells to necroptosis by destabilizing cIAP2 proteins	74
Targeting MMA-induced USP36 methylmalonylation to suppress macrophage polarization and tumor progression in clear-cell renal cell carcinoma	74
The birth of death, 30 years ago	73
Crotonylation of STXBP1 exacerbates seizure susceptibility by impairing GABAergic synaptic transmission	73
Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activato	72
The bone–liver interaction modulates immune and hematopoietic function through Pinch-Cxcl12-Mbl2 pathway	71
Disrupting CCDC137-mediated LZTS2 and β-TrCP interaction in the nucleus inhibits hepatocellular carcinoma development via β-catenin and AKT	69
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer	69
A chromosome-coupled ubiquitin-proteasome pathway is required for meiotic surveillance	67
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs	67
Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics	66
MLKL post-translational modifications: road signs to infection, inflammation and unknown destinations	66
KRAS mutation increases histone H3 lysine 9 lactylation (H3K9la) to promote colorectal cancer progression by facilitating cholesterol transporter GRAMD1A expression	65
Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent	63
S-phase targeted treatment triggers caspase-dependent lytic immunogenic cell death with pyroptotic features in cancers	61
Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress	59
RAB1A is a novel vulnerability in uveal melanoma revealed by dual inhibition of MNK1/2 and mTOR	59
The USP43/RNF2 axis negatively regulates antiviral innate immunity by promoting TBK1 ubiquitination and degradation	58
Daniel Aberdam, the legacy of a mentor	58
Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor	58
Dying in self-defense: cell death signaling in animals and plants	57
AF9 targets acetyl-modified STAT6 to diminish purine metabolism and accelerate cell apoptosis during metastasis	57
Correction: NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells	56
DPP9 inhibition boosts antitumor immunity by disrupting BRISC-mediated PD-L1 expression in clear cell renal cell carcinoma	55
CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity	54
Endothelial USP2a-METTL16 loop potentiates IL-6 signaling via m6A-mediated IL-6R stabilization in pulmonary vascular remodeling	54
DDHD2, whose mutations cause spastic paraplegia type 54, enhances lipophagy via engaging ATG8 family proteins	53
TRMT112 drives a tumor growth and metastasis-promoting program in triple-negative breast cancer	53