OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death and Differentiation is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response	674
NKAP acts with HDAC3 to prevent R-loop associated genome instability	462
PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions	409
Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development	367
HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2	338
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution	248
The scramblases VMP1 and TMEM41B are required for primitive endoderm specification by targeting WNT signaling	246
Retraction Note to: Glucose-6-phosphate dehydrogenase plays a crucial role in protection from redox-stress-induced apoptosis	237
Age-related p53 SUMOylation accelerates senescence and tau pathology in Alzheimer’s disease	223
A novel hypoxia-induced lncRNA, SZT2-AS1, boosts HCC progression by mediating HIF heterodimerization and histone trimethylation under a hypoxic microenvironment	203
Long Covid: where we stand and challenges ahead	201
Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt–β-catenin–STAT3 signaling	189
The Smad4-MYO18A-PP1A complex regulates β-catenin phosphorylation and pemigatinib resistance by inhibiting PAK1 in cholangiocarcinoma	186
Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis	169
NAT10 regulates mitotic cell fate by acetylating Eg5 to control bipolar spindle assembly and chromosome segregation	167
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment	155
Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a	143
USP2 promotes tumor immune evasion via deubiquitination and stabilization of PD-L1	138
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A	138
A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival	135
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease	134
Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent	125
The birth of death, 30 years ago	124
Disrupting CCDC137-mediated LZTS2 and β-TrCP interaction in the nucleus inhibits hepatocellular carcinoma development via β-catenin and AKT	119
A chromosome-coupled ubiquitin-proteasome pathway is required for meiotic surveillance	117

Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs	117
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer	115
CD63 acts as a functional marker in maintaining hematopoietic stem cell quiescence through supporting TGFβ signaling in mice	113
USP38 functions as an oncoprotein by downregulating the p53 pathway through deubiquitination and stabilization of MDM2	111
Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development	111
MLKL post-translational modifications: road signs to infection, inflammation and unknown destinations	105
Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics	104
The bone–liver interaction modulates immune and hematopoietic function through Pinch-Cxcl12-Mbl2 pathway	102
YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect	98
miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1	95
USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer	94
Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions	94
Sub-lethal signals in the mitochondrial apoptosis apparatus: pernicious by-product or physiological event?	89
AF9 targets acetyl-modified STAT6 to diminish purine metabolism and accelerate cell apoptosis during metastasis	88
CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity	87
A viral interferon regulatory factor degrades RNA-binding protein hnRNP Q1 to enhance aerobic glycolysis via recruiting E3 ubiquitin ligase KLHL3 and decaying GDPD1 mRNA	87
TIN2 modulates FOXO1 mitochondrial shuttling to enhance oxidative stress-induced apoptosis in retinal pigment epithelium under hyperglycemia	80
Chromosomal 3p loss and 8q gain drive vasculogenic mimicry via HIF-2α and VE-cadherin activation in uveal melanoma	77
Targeting necroptosis prevents viral-induced lung damage	77
Correction: NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells	76
Mapping the hotspots for DNA repair synthesis in human brain organoids	75
Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-1	74
Aberrant activation of p53/p66Shc-mInsc axis increases asymmetric divisions and attenuates proliferation of aged mammary stem cells	71
Dying in self-defense: cell death signaling in animals and plants	69
Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress	69
Correction: The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis	69
Post-transcriptional dynamics and RNA homeostasis in autophagy and cancer	66
The USP43/RNF2 axis negatively regulates antiviral innate immunity by promoting TBK1 ubiquitination and degradation	65
DDHD2, whose mutations cause spastic paraplegia type 54, enhances lipophagy via engaging ATG8 family proteins	64
lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus	63
Molecular mechanisms of cell death in neurological diseases	61
Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection	61
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer	60
Targeting N-glycosylation of 4F2hc mediated by glycosyltransferase B3GNT3 sensitizes ferroptosis of pancreatic ductal adenocarcinoma	58