OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death and Differentiation is 51. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
FAM96A functions as a novel pace controller for iron uptake to maintain iron homeostasis and erythropoiesis	381
Gut-derived hyodeoxycholate reprograms the spleen–eye immunometabolic axis to suppress autoimmune uveitis	358
HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2	332
PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions	283
Retraction Note to: Glucose-6-phosphate dehydrogenase plays a crucial role in protection from redox-stress-induced apoptosis	267
GPS2 regulates embryonic angiogenesis by enhancing endothelial cell survival through stabilizing HOIP	253
Correction: Epigenetic restriction of Hippo signaling by MORC2 underlies stemness of hepatocellular carcinoma cells	231
A novel hypoxia-induced lncRNA, SZT2-AS1, boosts HCC progression by mediating HIF heterodimerization and histone trimethylation under a hypoxic microenvironment	204
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment	171
The scramblases VMP1 and TMEM41B are required for primitive endoderm specification by targeting WNT signaling	167
TRIM11 potentiates antitumor immunity via inhibition of the IFN-γ/PD-L1 axis	143
NKAP acts with HDAC3 to prevent R-loop associated genome instability	140
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response	139
Age-related p53 SUMOylation accelerates senescence and tau pathology in Alzheimer’s disease	130
Non-pyroptotic caspase-11 activity regulates osteoclastogenesis and pathological bone loss	122
HECT ubiquitin ligases as regulators of inflammatory signalling	116
HERP constrains white adipose expansion and inflammation by STEAP4 stabilization	116
Long Covid: where we stand and challenges ahead	95
The E3 ubiquitin ligase Itch plays an essential role in kidney fibrosis by inhibiting Dvl2/GSK3β/β-catenin signaling pathway	94
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A	91
USP2 promotes tumor immune evasion via deubiquitination and stabilization of PD-L1	90
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease	89
MLKL post-translational modifications: road signs to infection, inflammation and unknown destinations	80
Disrupting CCDC137-mediated LZTS2 and β-TrCP interaction in the nucleus inhibits hepatocellular carcinoma development via β-catenin and AKT	80
Uridine 5’-monophosphate (UMP) synthesis connects nucleotide metabolism to programmed cell death in C. elegans	77

Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activato	76
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer	76
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs	72
A chromosome-coupled ubiquitin-proteasome pathway is required for meiotic surveillance	71
Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent	71
USP13 depletion sensitizes colorectal cancer cells to necroptosis by destabilizing cIAP2 proteins	70
The bone–liver interaction modulates immune and hematopoietic function through Pinch-Cxcl12-Mbl2 pathway	69
Targeting MMA-induced USP36 methylmalonylation to suppress macrophage polarization and tumor progression in clear-cell renal cell carcinoma	68
Crotonylation of STXBP1 exacerbates seizure susceptibility by impairing GABAergic synaptic transmission	67
KRAS mutation increases histone H3 lysine 9 lactylation (H3K9la) to promote colorectal cancer progression by facilitating cholesterol transporter GRAMD1A expression	65
USP38 functions as an oncoprotein by downregulating the p53 pathway through deubiquitination and stabilization of MDM2	64
The birth of death, 30 years ago	64
Daniel Aberdam, the legacy of a mentor	60
Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics	60
DDHD2, whose mutations cause spastic paraplegia type 54, enhances lipophagy via engaging ATG8 family proteins	59
Correction: The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis	59
TRMT112 drives a tumor growth and metastasis-promoting program in triple-negative breast cancer	59
Dying in self-defense: cell death signaling in animals and plants	58
Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor	57
AF9 targets acetyl-modified STAT6 to diminish purine metabolism and accelerate cell apoptosis during metastasis	56
Correction: NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells	55
Aberrant activation of p53/p66Shc-mInsc axis increases asymmetric divisions and attenuates proliferation of aged mammary stem cells	54
DPP9 inhibition boosts antitumor immunity by disrupting BRISC-mediated PD-L1 expression in clear cell renal cell carcinoma	54
TIN2 modulates FOXO1 mitochondrial shuttling to enhance oxidative stress-induced apoptosis in retinal pigment epithelium under hyperglycemia	53
Post-transcriptional dynamics and RNA homeostasis in autophagy and cancer	53
The TP53 gene contains a diversity box that makes it more than a tumor suppressor	52
Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions	51
Targeting N-glycosylation of 4F2hc mediated by glycosyltransferase B3GNT3 sensitizes ferroptosis of pancreatic ductal adenocarcinoma	51