OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death and Differentiation is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Non-pyroptotic caspase-11 activity regulates osteoclastogenesis and pathological bone loss	374
TRIM11 potentiates antitumor immunity via inhibition of the IFN-γ/PD-L1 axis	360
HERP constrains white adipose expansion and inflammation by STEAP4 stabilization	351
Long Covid: where we stand and challenges ahead	329
HECT ubiquitin ligases as regulators of inflammatory signalling	275
FAM96A functions as a novel pace controller for iron uptake to maintain iron homeostasis and erythropoiesis	264
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment	246
The scramblases VMP1 and TMEM41B are required for primitive endoderm specification by targeting WNT signaling	224
Age-related p53 SUMOylation accelerates senescence and tau pathology in Alzheimer’s disease	198
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A	172
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease	159
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response	137
Retraction Note to: Glucose-6-phosphate dehydrogenase plays a crucial role in protection from redox-stress-induced apoptosis	136
NKAP acts with HDAC3 to prevent R-loop associated genome instability	133
A novel hypoxia-induced lncRNA, SZT2-AS1, boosts HCC progression by mediating HIF heterodimerization and histone trimethylation under a hypoxic microenvironment	125
PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions	119
HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2	119
GPS2 regulates embryonic angiogenesis by enhancing endothelial cell survival through stabilizing HOIP	113
Correction: Epigenetic restriction of Hippo signaling by MORC2 underlies stemness of hepatocellular carcinoma cells	108
Gut-derived hyodeoxycholate reprograms the spleen–eye immunometabolic axis to suppress autoimmune uveitis	92
USP2 promotes tumor immune evasion via deubiquitination and stabilization of PD-L1	90
The birth of death, 30 years ago	89
Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent	86
Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activato	83
USP13 depletion sensitizes colorectal cancer cells to necroptosis by destabilizing cIAP2 proteins	78

The bone–liver interaction modulates immune and hematopoietic function through Pinch-Cxcl12-Mbl2 pathway	77
Uridine 5’-monophosphate (UMP) synthesis connects nucleotide metabolism to programmed cell death in C. elegans	77
Crotonylation of STXBP1 exacerbates seizure susceptibility by impairing GABAergic synaptic transmission	74
Disrupting CCDC137-mediated LZTS2 and β-TrCP interaction in the nucleus inhibits hepatocellular carcinoma development via β-catenin and AKT	72
Targeting MMA-induced USP36 methylmalonylation to suppress macrophage polarization and tumor progression in clear-cell renal cell carcinoma	72
MLKL post-translational modifications: road signs to infection, inflammation and unknown destinations	71
A chromosome-coupled ubiquitin-proteasome pathway is required for meiotic surveillance	70
USP38 functions as an oncoprotein by downregulating the p53 pathway through deubiquitination and stabilization of MDM2	70
KRAS mutation increases histone H3 lysine 9 lactylation (H3K9la) to promote colorectal cancer progression by facilitating cholesterol transporter GRAMD1A expression	68
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs	66
Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics	64
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer	63
Daniel Aberdam, the legacy of a mentor	63
A viral interferon regulatory factor degrades RNA-binding protein hnRNP Q1 to enhance aerobic glycolysis via recruiting E3 ubiquitin ligase KLHL3 and decaying GDPD1 mRNA	62
The TP53 gene contains a diversity box that makes it more than a tumor suppressor	62
USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer	61
Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress	60
DDHD2, whose mutations cause spastic paraplegia type 54, enhances lipophagy via engaging ATG8 family proteins	58
Correction: The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis	57
TRMT112 drives a tumor growth and metastasis-promoting program in triple-negative breast cancer	57
Dying in self-defense: cell death signaling in animals and plants	57
Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor	56
AF9 targets acetyl-modified STAT6 to diminish purine metabolism and accelerate cell apoptosis during metastasis	55
Correction: NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells	55
Aberrant activation of p53/p66Shc-mInsc axis increases asymmetric divisions and attenuates proliferation of aged mammary stem cells	54
DPP9 inhibition boosts antitumor immunity by disrupting BRISC-mediated PD-L1 expression in clear cell renal cell carcinoma	54
Targeting necroptosis prevents viral-induced lung damage	53