OOIR: Observatory of International Research

Papers

(The H4-Index of Cancer Science is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
5‐Fluorouracil resistance mechanisms in colorectal cancer: From classical pathways to promising processes	221
Reactive oxygen species in cancer: Current findings and future directions	197
Tumor microenvironment in gastric cancers	155
Artificial intelligence in oncology	149
Tumor immune microenvironment and immune checkpoint inhibitors in esophageal squamous cell carcinoma	136
Biology and therapeutic potential of mesenchymal stem cell‐derived exosomes	124
Pyroptosis, a new bridge to tumor immunity	106
Cancer‐associated fibroblasts that restrain cancer progression: Hypotheses and perspectives	101
Heterogeneity of cancer‐associated fibroblasts: Opportunities for precision medicine	98
Icariin‐induced inhibition of SIRT6/NF‐κB triggers redox mediated apoptosis and enhances anti‐tumor immunity in triple‐negative breast cancer	88
CAR‐NK cell in cancer immunotherapy; A promising frontier	82
Circular RNA LPAR3 sponges microRNA‐198 to facilitate esophageal cancer migration, invasion, and metastasis	82
Predictive and sensitive biomarkers for thyroid dysfunctions during treatment with immune‐checkpoint inhibitors	82
Ferroptosis at the crossroads of infection, aging and cancer	80
TNF‐α enhances TGF‐β‐induced endothelial‐to‐mesenchymal transition via TGF‐β signal augmentation	76
CIRCULATE‐Japan: Circulating tumor DNA–guided adaptive platform trials to refine adjuvant therapy for colorectal cancer	71
Non–clinical efficacy, safety and stable clinical cell processing of induced pluripotent stem cell‐derived anti–glypican‐3 chimeric antigen receptor‐expressing natural killer/innate lymphoid cells	71
Serum exosomal miR‐638 is a prognostic marker of HCC via downregulation of VE‐cadherin and ZO‐1 of endothelial cells	68
Real‐world data on microsatellite instability status in various unresectable or metastatic solid tumors	68
Interstitial pneumonitis related to trastuzumab deruxtecan, a human epidermal growth factor receptor 2‐targeting Ab–drug conjugate, in monkeys	64
MicroRNA‐375‐3p enhances chemosensitivity to 5‐fluorouracil by targeting thymidylate synthase in colorectal cancer	63
Relationship among DNA double‐strand break (DSB), DSB repair, and transcription prevents genome instability and cancer	60
Cancer‐associated adipocytes promote pancreatic cancer progression through SAA1 expression	59
A multicenter, open‐label, phase II study of tirabrutinib (ONO/GS‐4059) in patients with Waldenström’s macroglobulinemia	58
Tislelizumab in Asian patients with previously treated locally advanced or metastatic urothelial carcinoma	58

Tetrahedral DNA nanostructures as drug delivery and bioimaging platforms in cancer therapy	57
Ferroptosis‐related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma	57
Functional diversity of cancer‐associated fibroblasts in modulating drug resistance	53
Reprograming the tumor immunologic microenvironment using neoadjuvant chemotherapy in osteosarcoma	50
Alectinib for relapsed or refractory anaplastic lymphoma kinase‐positive anaplastic large cell lymphoma: An open‐label phase II trial	49
RNA sequencing of plasma exosomes revealed novel functional long noncoding RNAs in hepatocellular carcinoma	48
Lipid accumulation in macrophages confers protumorigenic polarization and immunity in gastric cancer	47
Gut‐liver axis‐mediated mechanism of liver cancer: A special focus on the role of gut microbiota	46
A ceRNA network and a potential regulatory axis in gastric cancer with different degrees of immune cell infiltration	45
Abemaciclib induces atypical cell death in cancer cells characterized by formation of cytoplasmic vacuoles derived from lysosomes	45
Risk stratification for the prognosis of patients with chemoresistant urothelial cancer treated with pembrolizumab	44
The roles and regulation of the KLF5 transcription factor in cancers	42
Feasibility and utility of transbronchial cryobiopsy in precision medicine for lung cancer: Prospective single‐arm study	42
Nuclear microenvironment in cancer: Control through liquid‐liquid phase separation	42
Synthetic lethality strategies: Beyond BRCA1/2 mutations in pancreatic cancer	42
Corrected human papillomavirus vaccination rates for each birth fiscal year in Japan	42
RNA‐dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID‐19	42