OOIR: Observatory of International Research

Papers

(The H4-Index of Cancer Science is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Reactive oxygen species in cancer: Current findings and future directions	343
Pyroptosis, a new bridge to tumor immunity	123
Icariin‐induced inhibition of SIRT6/NF‐κB triggers redox mediated apoptosis and enhances anti‐tumor immunity in triple‐negative breast cancer	102
CAR‐NK cell in cancer immunotherapy; A promising frontier	89
Real‐world data on microsatellite instability status in various unresectable or metastatic solid tumors	85
Serum exosomal miR‐638 is a prognostic marker of HCC via downregulation of VE‐cadherin and ZO‐1 of endothelial cells	83
CIRCULATE‐Japan: Circulating tumor DNA–guided adaptive platform trials to refine adjuvant therapy for colorectal cancer	82
Interstitial pneumonitis related to trastuzumab deruxtecan, a human epidermal growth factor receptor 2‐targeting Ab–drug conjugate, in monkeys	74
Ferroptosis‐related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma	72
Tislelizumab in Asian patients with previously treated locally advanced or metastatic urothelial carcinoma	70
The roles and regulation of the KLF5 transcription factor in cancers	60
Clonal hematopoiesis and associated diseases: A review of recent findings	57
Alectinib for relapsed or refractory anaplastic lymphoma kinase‐positive anaplastic large cell lymphoma: An open‐label phase II trial	56
Gut‐liver axis‐mediated mechanism of liver cancer: A special focus on the role of gut microbiota	55
Tumor‐homing peptide and its utility for advanced cancer medicine	54
The gut microbiota associated with high‐Gleason prostate cancer	54
Liposomal irinotecan (Onivyde): Exemplifying the benefits of nanotherapeutic drugs	53
The noncanonical role of EZH2 in cancer	51
Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells	51
Amino acid transporters as emerging therapeutic targets in cancer	50
Risk stratification for the prognosis of patients with chemoresistant urothelial cancer treated with pembrolizumab	49
Ferroptosis is induced by lenvatinib through fibroblast growth factor receptor‐4 inhibition in hepatocellular carcinoma	48
IGF2BP2 promotes the progression of colorectal cancer through a YAP‐dependent mechanism	48
H19 promotes aerobic glycolysis, proliferation, and immune escape of gastric cancer cells through the microRNA‐519d‐3p/lactate dehydrogenase A axis	48
SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling	47

Establishment and implementation of Cancer Genomic Medicine in Japan	45
Immune infiltration profiling in gastric cancer and their clinical implications	45
Enhanced anti‐tumor effects of the PD‐1 blockade combined with a highly absorptive form of curcumin targeting STAT3	44
Low‐dose decitabine plus venetoclax is safe and effective as post‐transplant maintenance therapy for high‐risk acute myeloid leukemia and myelodysplastic syndrome	43
Immunosuppressive activity is attenuated by Astragalus polysaccharides through remodeling the gut microenvironment in melanoma mice	43
Proteomic analysis of urinary and tissue‐exudative extracellular vesicles to discover novel bladder cancer biomarkers	42
Clinical characterization and immunosuppressive regulation of CD161 (KLRB1) in glioma through 916 samples	42
PDL1‐positive exosomes suppress antitumor immunity by inducing tumor‐specific CD8⁺ T cell exhaustion during metastasis	42
The heterogeneity of cancer‐associated fibroblast subpopulations: Their origins, biomarkers, and roles in the tumor microenvironment	41
Real‐world data on NGS using the Oncomine DxTT for detecting genetic alterations in non‐small‐cell lung cancer: WJOG13019L	41
Regulation of vascular permeability in cancer metastasis	41
Long noncoding RNA just proximal to X‐inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A‐dependent manner in gli	40
Prognosis of patients with adult T‐cell leukemia/lymphoma in Japan: A nationwide hospital‐based study	39
Concomitant overexpression of mir‐182‐5p and mir‐182‐3p raises the possibility of IL‐17–producing Treg formation in breast cancer by targeting CD3d, ITK, FOXO1, and NFATs: A meta‐analysis and experime	39
Aptamer‐based biosensors and application in tumor theranostics	39