Journal of Pharmacological Sciences

Article	Citations
Glutamate-induced excitotoxicity in Parkinson's disease: The role of glial cells	166
Microglial metabolic disturbances and neuroinflammation in cerebral infarction	72
ABCA1 and ABCG1 as potential therapeutic targets for the prevention of atherosclerosis	63
Chrysophanol attenuates hepatitis B virus X protein-induced hepatic stellate cell fibrosis by regulating endoplasmic reticulum stress and ferroptosis	56
Ellagic acid attenuates liver toxicity induced by valproic acid in rats	54
Potential roles of astrocytes and Müller cells in the pathogenesis of glaucoma	40
Zinc transporters as potential therapeutic targets: An updated review	38
Inhibition of STAT3 phosphorylation attenuates impairments in learning and memory in 5XFAD mice, an animal model of Alzheimer's disease	36
Artesunate induces ferroptosis via modulation of p38 and ERK signaling pathway in glioblastoma cells	31
Alleviation of the doxorubicin-induced nephrotoxicity by fasudil in vivo and in vitro	30
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism	29
The roles of astrocytic phagocytosis in maintaining homeostasis of brains	29
Predictive role of vitamin A serum concentration in psoriatic patients treated with IL-17 inhibitors to prevent skin and systemic fungal infections	28
Tong-fu-li-fei decoction exerts a protective effect on intestinal barrier of sepsis in rats through upregulating ZO-1/occludin/claudin-1 expression	28
CCND1 silencing suppresses liver cancer stem cell differentiation and overcomes 5-Fluorouracil resistance in hepatocellular carcinoma	27
Analysis of binding affinity and docking of novel fatty acid-binding protein (FABP) ligands	25
Computational study of the therapeutic potentials of a new series of imidazole derivatives against SARS-CoV-2	24
Phosphatase-independent functions of SHP2 and its regulation by small molecule compounds	23
Sevoflurane induces inflammation of microglia in hippocampus of neonatal rats by inhibiting Wnt/β-Catenin/CaMKIV pathway	23
Hyperoside ameliorates diabetic nephropathy induced by STZ via targeting the miR-499–5p/APC axis	23
Exosomes derived from human umbilical cord mesenchymal stem cells alleviate acetaminophen-induced acute liver failure through activating ERK and IGF-1R/PI3K/AKT signaling pathway	22
JPH203, a newly developed anti-cancer drug, shows a preincubation inhibitory effect on L-type amino acid transporter 1 function	22
MitoQ protects against high glucose-induced brain microvascular endothelial cells injury via the Nrf2/HO-1 pathway	21
Microglial heterogeneity in aging and Alzheimer's disease: Is sex relevant?	21
TLR4-TAK1-p38 MAPK pathway and HDAC6 regulate the expression of sigma-1 receptors in rat primary cultured microglia	21

Manganese transport in mammals by zinc transporter family proteins, ZNT and ZIP	20
Microglia as therapeutic target in central nervous system disorders	20
Sestrin2 protects against bavachin induced ER stress through AMPK/mTORC1 signaling pathway in HepG2 cells	19
Andrographolide sulfate inhibited NF-κB activation and alleviated pneumonia induced by poly I:C in mice	18
RETRACTED: LncRNA NEAT1 acts as a key regulator of cell apoptosis and inflammatory response by the miR-944/TRIM37 axis in acute lung injury	18
Kaempferol, the melanogenic component of Sanguisorba officinalis, enhances dendricity and melanosome maturation/transport in melanocytes	17
Inflammation in the brain and periphery found in animal models of depression and its behavioral relevance	17
Ginsenoside Rg1 promoted the wound healing in diabetic foot ulcers via miR-489–3p/Sirt1 axis	17
Lymphangiogenesis induced by vascular endothelial growth factor receptor 1 signaling contributes to the progression of endometriosis in mice	17
Safranal, an active constituent of saffron, ameliorates myocardial ischemia via reduction of oxidative stress and regulation of Ca2+ homeostasis	16
Wilforlide A ameliorates the progression of rheumatoid arthritis by inhibiting M1 macrophage polarization	16
L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy	16
Ferulic acid attenuates non-alcoholic steatohepatitis by reducing oxidative stress and inflammation through inhibition of the ROCK/NF-κB signaling pathways	16
Renoprotective effect of isoliquiritigenin on cisplatin-induced acute kidney injury through inhibition of FPR2 in macrophage	16
Liver hydrolysate improves depressive-like behavior in olfactory bulbectomized mice: Involvement of hippocampal neurogenesis through the AMPK/BDNF/CREB pathway	16
Protective effect of Clinopodium chinense (Benth.) O. Kuntze against abnormal uterine bleeding in female rats	15
Piezo 1 is involved in intraocular pressure regulation	15
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora	15
Ursolic acid treatment suppresses cuprizone-induced demyelination and motor dysfunction via upregulation of IGF-1	15
The assessment of mouse spontaneous locomotor activity using motion picture	15
Liquiritigenin reduces osteoclast activity in zebrafish model of glucocorticoid-induced osteoporosis	15
SARS-CoV-2 induces barrier damage and inflammatory responses in the human iPSC-derived intestinal epithelium	15
Comparison of the anti-colitis activities of Qing Dai/Indigo Naturalis constituents in mice	15
Involvement of exchange protein directly activated by cAMP and tumor progression locus 2 in IL-1β production in microglial cells following activation of β-adrenergic receptors	14
Effects of post-renal anemia treatment with the HIF-PHD inhibitor molidustat on adenine-induced renal anemia and kidney disease in mice	14
Dopamine D1 receptor agonist A68930 attenuates acute kidney injury by inhibiting NLRP3 inflammasome activation	14
Pterostilbene alleviates liver ischemia/reperfusion injury via PINK1-mediated mitophagy	14
Centrally administered butyrate improves gut barrier function, visceral sensation and septic lethality in rats	14
Survival motor neuron protein regulates oxidative stress and inflammatory response in microglia of the spinal cord in spinal muscular atrophy	14
Rutaecarpine exhibits anti-diabetic potential in high fat diet–multiple low dose streptozotocin induced type 2 diabetic mice and in vitro by modulating hepatic glucose homeostasis	14
Astrocytic Ca2+ signaling mediated by the endoplasmic reticulum in health and disease	14
Drug repurposing for the treatment of COVID-19	13
Pluripotent anti-inflammatory immunomodulatory effects of papaverine against cerebral ischemic-reperfusion injury	13
Estrogen decline is a risk factor for paclitaxel-induced peripheral neuropathy: Clinical evidence supported by a preclinical study	13
Perisynaptic astrocytes as a potential target for novel antidepressant drugs	13
Hsa_circ_0008225 inhibits tumorigenesis of glioma via sponging miR-890 and promoting ZMYND11 expression	13
Granisetron attenuates liver injury and inflammation in a rat model of cecal ligation and puncture-induced sepsis	13
Resolvins as potential candidates for the treatment of major depressive disorder	13
FoxM1 inhibition ameliorates renal interstitial fibrosis by decreasing extracellular matrix and epithelial–mesenchymal transition	13
Safety and effectiveness of oral blonanserin for schizophrenia: A review of Japanese post-marketing surveillances	13
Prolyl-hydroxylase inhibitors reconstitute tumor blood vessels in mice	13
A machine learning model that emulates experts’ decision making in vancomycin initial dose planning	12
Dihydrocapsaicin-induced angiogenesis and improved functional recovery after cerebral ischemia and reperfusion in a rat model	12
Comparison of cytotoxicity of cigarette smoke extract derived from heat-not-burn and combustion cigarettes in human vascular endothelial cells	12
The ginsenoside metabolite compound K stimulates glucagon-like peptide-1 secretion in NCI–H716 cells by regulating the RhoA/ROCKs/YAP signaling pathway and cytoskeleton formation	12
Ramelteon modulates gamma oscillations in the rat primary motor cortex during non-REM sleep	12
Emodin-induced autophagic cell death hinders epithelial–mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis	12
Metformin suppresses phenylephrine-induced hypertrophic responses by inhibiting p300-HAT activity in cardiomyocytes	12
CP-25 ameliorates methotrexate induced nephrotoxicity via improving renal apoptosis and methotrexate excretion	12
MiR-23b-3p promotes postmenopausal osteoporosis by targeting MRC2 and regulating the Wnt/β-catenin signaling pathway	12

The role of nitric oxide in small intestine differs between a single and a consecutive administration of methotrexate to rats	11
3-Methyladenine prevents energy stress-induced necrotic death of melanoma cells through autophagy-independent mechanisms	11
Juzentaihoto improves adenine-induced chronic renal failure in BALB/c mice via suppression of renal fibrosis and inflammation	11
Calunduloside E inhibits HepG2 cell proliferation and migration via p38/JNK-HMGB1 signalling axis	11
The roles of lipid mediators in type I hypersensitivity	11
Mirogabalin activates the descending noradrenergic system by binding to the α2δ-1 subunit of voltage-gated Ca2+ channels to generate analgesic effects	11
Terrein suppressed lipopolysaccharide-induced neuroinflammation through inhibition of NF-κB pathway by activating Nrf2/HO-1 signaling in BV2 and primary microglial cells	11
Reactive pericytes in early phase are involved in glial activation and late-onset hypersusceptibility to pilocarpine-induced seizures in traumatic brain injury model mice	11
Aqueous extracts of Lindera aggregate (Sims) Kosterm leaves regulate serum/hepatic lipid and liver function in normal and hypercholesterolemic mice	11
Extracellular Ca2+ promotes nitric oxide production via Ca2+-sensing receptor-Gq/11 protein-endothelial nitric oxide synthase signaling in human vascular endothelial cells	10
A potent antiarrhythmic drug N-methyl berbamine extends the action potential through inhibiting both calcium and potassium currents	10
Paeoniflorin elicits the anti-proliferative effects on glioma cell via targeting translocator protein 18 KDa	10
Inhibitory effect of panaxytriol on BV-2 microglial cell activation	10
HDL, cholesterol efflux, and ABCA1: Free from good and evil dualism	10
Capsaicinoid nonivamide improves nonalcoholic fatty liver disease in rats fed a high-fat diet	10
Echinacoside prevents hypoxic pulmonary hypertension by regulating the pulmonary artery function	10
Pentagalloylglucose reduces AGE-induced inflammation by activating Nrf2/HO-1 and inhibiting the JAK2/STAT3 pathway in mesangial cells	10
Effects of anti-osteoporosis drugs against dexamethasone-induced osteoporosis-like phenotype using a zebrafish scale-regeneration model	10
Comparative analysis of age in monocrotaline-induced pulmonary hypertensive rats	9
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux	9
Phloroglucinol attenuates oligomeric amyloid beta peptide1-42-induced astrocytic activation by reducing oxidative stress	9
Microglia modulate the structure and function of the hippocampus after early-life seizures	9
Fructo-oligosaccharides alleviate inflammation-associated apoptosis of GLP-1 secreting L cells via inhibition of iNOS and cleaved caspase-3 expression	9
Metformin regulates the Th17/Treg balance by glycolysis with TIGAR in hepatic ischemia-reperfusion injury	9
Icariin inhibits epithelial mesenchymal transition of renal tubular epithelial cells via regulating the miR-122-5p/FOXP2 axis in diabetic nephropathy rats	9
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway	9
Blueberry anthocyanins extract attenuated diabetic retinopathy by inhibiting endoplasmic reticulum stress via the miR-182/OGG1 axis	9
A Japanese herbal medicine attenuates anxiety-like behavior through GABAA receptor and brain-derived neurotrophic factor expression in a rat model of premenstrual syndrome	9
Dihydroartemisinin regulates apoptosis, migration, and invasion of ovarian cancer cells via mediating RECK	9
An assessment of the spontaneous locomotor activity of BALB/c mice	9
Effects of 17-AAG on the RIP1/RIP3/MLKL pathway during the development of heart failure following myocardial infarction in rats	9
Genetic associations of single nucleotide polymorphisms in the l-DOPA receptor (GPR143) gene with severity of nicotine dependence in Japanese individuals, and attenuation of nicotine reinforcement in	8
Xingnaojing ameliorates synaptic plasticity and memory deficits in an Aβ1–42 induced mouse model of Alzheimer's disease	8
Nicotine enhances object recognition memory through inhibition of voltage-dependent potassium 7 channels in the medial prefrontal cortex of mice	8
Presynaptically silent synapses are modulated by the density of surrounding astrocytes	8
Establishing a high throughput drug screening system for cerebral ischemia using zebrafish larvae	8
Entecavir as a P2X7R antagonist ameliorates platelet activation and thrombus formation	8
Administration of cyclophosphamide to rats induces pica and potentiates 5-hydroxytryptamine synthesis in the intestine without causing severe intestinal injury	8
Pharmacological inhibition of mitochondrial fission attenuates oxidative stress-induced damage of retinal pigmented epithelial cells	8
Deletion of intestinal SIRT1 exacerbated muscle wasting in cirrhotic mice by decreasing the intestinal concentration of short-chain fatty acids and inflammation	8
Dermatophagoides pteronyssinus-induced pro-inflammatory responses mediated via STAT3 and NF-kappaB signaling pathways in human bronchial epithelial cells – Inhibitory effects of Lafoensia pacari and e	8
Activation of the angiotensin II receptor promotes autophagy in renal proximal tubular cells and affords protection from ischemia/reperfusion injury	8
Adipose-specific knockout of ubiquitin-conjugating enzyme E2L6 (Ube2l6) reduces diet-induced obesity, insulin resistance, and hepatic steatosis	8
Mucin 1 regulates the hypoxia response in head and neck cancer cells	8
Novel aspects of sepsis pathophysiology: NETs, plasma glycoproteins, endotheliopathy and COVID-19	8
In vivo comparison of dl-sotalol-induced electrocardiographic responses among halothane anesthesia, isoflurane anesthesia with nitrous oxide, and conscious state	8
Orientin reverses acetaminophen-induced acute liver failure by inhibiting oxidative stress and mitochondrial dysfunction	8
Role of reactive astrocytes in the spinal dorsal horn under chronic itch conditions	8
IL-1β promotes osteoclastogenesis by increasing the expression of IGF2 and chemokines in non-osteoclastic cells	7
Gastrodin - A potential drug used for the treatment of Tourette Syndrome	7
N-linoleyltyrosine exerts neuroprotective effects in APP/PS1 transgenic mice via cannabinoid receptor-mediated autophagy	7
Sustained increased CaMKII phosphorylation is involved in the impaired regression of isoproterenol-induced cardiac hypertrophy in rats	7
Serotonin transporter: Recent progress of in silico ligand prediction methods and structural biology towards structure-guided in silico design of therapeutic agents	7
Impact of fatty acid-binding proteins and dopamine receptors on α-synucleinopathy	7
Linalyl acetate as a potential preventive agent against muscle wasting in rheumatoid arthritis rats chronically exposed to nicotine	7
Electrophysiological responses to seizurogenic compounds dependent on E/I balance in human iPSC-derived cortical neural networks	7
T-type Ca2+ channel enhancer SAK3 administration improves the BPSD-like behaviors in AppNL−G-F/NL−G-F knock-in mice	7
Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages	7
Hypoxia increases the proliferation of brain capillary endothelial cells via upregulation of TMEM16A Ca2+-activated Cl− channels	7
Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice	7
Exposure to methamphetamine exacerbates motor activities and alters circular RNA profile of cerebellum	7
Potential treatments of COVID-19: Drug repurposing and therapeutic interventions	7
Analysis of effects of acute hypovolemia on arterial stiffness in rabbits monitored with cardio-ankle vascular index	6
In vivo analysis of concentration-dependent effects of halothane or isoflurane inhalation on the electrocardiographic and hemodynamic variables in dogs	6
HMGB1 and its membrane receptors as therapeutic targets in an intravesical substance P-induced bladder pain syndrome mouse model	6
Protective effect of SGL5213, a potent intestinal sodium–glucose cotransporter 1 inhibitor, in nonalcoholic fatty liver disease in mice	6
Sesamin promotes apoptosis and pyroptosis via autophagy to enhance antitumour effects on murine T-cell lymphoma	6
Serum stratifin and presepsin as candidate biomarkers for early detection of COVID-19 disease progression	6
LncRNA HOXC-AS1 promotes nasopharyngeal carcinoma (NPC) progression by sponging miR-4651 and subsequently upregulating FOXO6	6
Andrographolide improves PCP-induced schizophrenia-like behaviors through blocking interaction between NRF2 and KEAP1	6
Reduced mitochondrial complex II activity enhances cell death via intracellular reactive oxygen species in STHdhQ111 striatal neurons with mutant huntingtin	6
Finding a resveratrol analogue as potential anticancer agent with apoptosis and cycle arrest	6
The transcription factor Hhex regulates inflammation-related genes in microglia	6
Post-weaning folate deficiency induces a depression-like state via neuronal immaturity of the dentate gyrus in mice	6
Selective histamine H2 receptor agonists alleviate blood-brain barrier disruption by promoting the expression of vascular protective factors following traumatic brain injury in mice	6
Pravastatin alleviates intracellular calcium dysregulation induced by Interleukin-6 via the mitochondrial ROS pathway in adult ventricular myocytes	6
circ_0101802 functions as a sponge of miR-1236-3p to facilitate the proliferation, migration and invasion of colorectal cancer via regulating MACC1	6
Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes	6
Quantitative prediction of pharmacokinetic properties of drugs in humans: Recent advance in in vitro models to predict the impact of efflux transporters in the small intestine and blood–brain barrier	6
Transcutaneous immunization with a highly active form of XCL1 as a vaccine adjuvant using a hydrophilic gel patch elicits long-term CD8+ T cell responses	6

Effect of Piper cubeba total extract and isolated lignans on head and neck cancer cell lines and normal fibroblasts	6
Sigma-1 receptor is involved in modification of ER-mitochondria proximity and Ca2+ homeostasis in cardiomyocytes	6
Characteristics and therapeutic potential of sodium-dependent phosphate cotransporters in relation to idiopathic basal ganglia calcification	6
Effect of nevirapine, efavirenz and lopinavir/ritonavir on the therapeutic concentration and toxicity of lumefantrine in people living with HIV at Lagos University Teaching Hospital, Nigeria	6
The protective effect of Centella asiatica and its constituent, araliadiol on neuronal cell damage and cognitive impairment	6
Insulin-like growth factor 2 promotes osteoclastogenesis increasing inflammatory cytokine levels under hypoxia	5
Vascular sympathetic neurotransmission and its serotonergic regulation are modified by chronic fluoxetine treatment	5
Pentoxifylline treatment alleviates kidney ischemia/reperfusion injury: Novel involvement of galectin-3 and ASK-1/JNK & ERK1/2/NF-κB/HMGB-1 trajectories	5
Involvement of TREK1 channels in the proliferation of human hepatic stellate LX-2 cells	5
A novel JAK/ROCK inhibitor, CPL409116, demonstrates potent efficacy in the mouse model of systemic lupus erythematosus	5
Torsadogenic potential of a novel remyelinating drug clemastine for multiple sclerosis assessed in the rabbit proarrhythmia model	5
Eukaryotic elongation factor 2 kinase inhibitor, A484954 lowered blood pressure in spontaneously hypertensive rats via inducing vasorelaxation	5
Dencichine prevents ovariectomy-induced bone loss and inhibits osteoclastogenesis by inhibiting RANKL-associated NF-κB and MAPK signaling pathways	5
Guanabenz inhibits alveolar bone resorption in a rat model of periodontitis	5
Nafamostat protects against early brain injury after subarachnoid hemorrhage in mice	5
PP2A regulates metastasis and vasculogenic mimicry formation via PI3K/AKT/ZEB1 axis in non-small cell lung cancers	5
Switching opioid-dependent patients in substitution treatment from racemic methadone, levomethadone and buprenorphine to slow-release oral morphine: Analysis of the switching process in routine care	5
Inhibition of α2-adrenoceptor is renoprotective in 5/6 nephrectomy-induced chronic kidney injury rats	5
Pinostrobin inhibits renal CFTR-mediated Cl− secretion and retards cyst growth in cell-derived cyst and polycystic kidney disease rats	5
Impact of genetic polymorphisms on the pharmacokinetics and pharmacodynamics of lenvatinib in patients with hepatocellular carcinoma	5
MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations	5
Probing the chemoprevention potential of the antidepressant fluoxetine combined with epigallocatechin gallate or kaempferol in rats with induced early stage colon carcinogenesis	5
Opposing functions of α- and β-adrenoceptors in the formation of processes by cultured astrocytes	5
Experimental evidence for the involvement of F0/F1 ATPase and subsequent P2Y12 receptor activation in prothymosin alpha-induced protection of retinal ischemic damage	5
Chronic magnesium deficiency causes reversible mitochondrial permeability transition pore opening and impairs hypoxia tolerance in the rat heart	5
Sensitivity of inhalation anesthetics isoflurane and sevoflurane for the drug-induced QT-interval prolongation in guinea pigs	5
Role of neuron-derived ATP in paclitaxel-induced HMGB1 release from macrophages and peripheral neuropathy	5
Negative impact of anesthesia with midazolam, sufentanil, and propofol used in pediatric flexible bronchoscopy on the tracheal ciliary beat frequency in guinea pigs	5
EMA401, an angiotensin II type 2 receptor antagonist blocks visceral hypersensitivity and colonic hyperpermeability in rat model of irritable bowel syndrome	5
Syntaxin 3 interacts with serotonin transporter and regulates its function	5
Calycosin pretreatment enhanced the therapeutic efficacy of mesenchymal stem cells to alleviate unilateral ureteral obstruction-induced renal fibrosis by inhibiting necroptosis	4
Influence of light–dark cycle on delayed recovery from isoflurane anesthesia induced by hypnotics in mice	4
A purine derivative, paraxanthine, promotes cysteine uptake for glutathione synthesis	4
Neuroprotective effects of 5-aminolevulinic acid against neurodegeneration in rat models of Parkinson's disease and stroke	4
Sodium/glucose cotransporter 2 and renoprotection: From the perspective of energy regulation and water conservation	4
Post-transcriptional regulation activity through alternative splicing involved in the effects of Aloe vera on the Wnt/β-catenin and Notch pathways in colorectal cancer cells	4
Development of in vitro three-dimensional drug screening system for obesity-related metabolic syndrome	4
Overview for the study of P2 receptors: From P2 receptor history to neuropathic pain studies	4
Circular RNA circPSAP functions as an efficient miR-331-3p sponge to regulate proliferation, apoptosis and bortezomib sensitivity of human multiple myeloma cells by upregulating HDAC4	4
The emerging roles and therapeutic potential of cyclin M/CorC family of Mg2+ transporters	4
A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats	4
Stathmin expression alters the antiproliferative effect of eribulin in leiomyosarcoma cells	4
Novel FABP3 ligand, HY-11-9, ameliorates neuropathological deficits in MPTP-induced Parkinsonism in mice	4
Efficacy and safety of propranolol cream in infantile hemangioma: A prospective pilot study	4
Polygalaxanthone III downregulates inflammation in the lipopolysaccharide-stimulated RAW264.7 macrophages: A quantibody array analysis	4
The dorsal hippocampal protein targeting to glycogen maintains ionotropic glutamate receptor subunits expression and contributes to working and short-term memories in mice	4
Right ventricular overloading is attenuated in monocrotaline-induced pulmonary hypertension model rats with a disrupted Gpr143 gene, the gene that encodes the 3,4-l-dihydroxyphenyalanine (l-DOPA) rece	4
Yokukansankachimpihange, a traditional Japanese (Kampo) medicine, enhances the adaptation to circadian rhythm disruption by increasing endogenous melatonin levels	4
Lactucin & Lactucopicrin ameliorates FFA-induced steatosis in HepG2 cells via modulating lipid metabolism	4
Analysis of clinically-reported, memantine-induced cardiovascular adverse responses using the halothane-anesthetized dogs: Reverse translational study	4
Mechanism of canagliflozin-induced vasodilation in resistance mesenteric arteries and the regulation of systemic blood pressure	4
Paeoniflorin, ferulic acid, and atractylenolide III improved LPS-induced neuroinflammation of BV2 microglia cells by enhancing autophagy	4
Ibudilast suppresses oxaliplatin-induced mechanical allodynia and neurodegeneration in rats	4
Aronia melanocarpa polysaccharide ameliorates liver fibrosis through TGF-β1-mediated the activation of PI3K/AKT pathway and modulating gut microbiota	4
In vivo analysis of the effects of intravenously as well as orally administered moxifloxacin on the pharmacokinetic and electrocardiographic variables along with its torsadogenic action in the chronic	4
Control of rat bladder neck relaxation with NORD-1, a red light–reactive nitric oxide releaser: In vitro study	4
Clofibrate improves myocardial ischemia-induced damage through regulation of renin-angiotensin system and favours a pro-vasodilator profile in left ventricle	4
KCa3.1 inhibition-induced activation of the JNK/c-Jun signaling pathway enhances IL-10 expression in peripherally-induced regulatory T cells	4
ERK5 inhibitor BIX02189 attenuates methamphetamine-induced hyperactivity by modulating microglial activation in the striatum	4
Peficitinib improves bone fragility by recovering bone turnover imbalance in arthritic mice	4
Role of transient receptor potential vanilloid subtype 2 in lower oesophageal sphincter in rat acid reflux oesophagitis	4
Involvement of endoplasmic reticulum stress in rotenone-induced leber hereditary optic neuropathy model and the discovery of new therapeutic agents	4
Sperm-associated antigen 6 (Spag6) mutation leads to vestibular dysfunction in mice	3
Peficitinib inhibits fibroblast-like synoviocyte activation and angiogenic vascular endothelial tube formation via inhibitory effects on PDGF and VEGF signaling in addition to JAK	3
Histamine promotes angiogenesis through a histamine H1 receptor-PKC-VEGF-mediated pathway in human endothelial cells	3
Functional characteristics and therapeutic potential of SLC41 transporters	3
Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic–polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells	3
Characterization of serotonin as a candidate biomarker of severity and prognosis of COVID-19 using LC/MS analysis	3
Dopamine inhibits the expression of proinflammatory cytokines of microglial cells through the formation of dopamine quinone in the mouse striatum	3
Endoplasmic reticulum stress-regulated high temperature requirement A1 (HTRA1) modulates invasion and angiogenesis-related genes in human trophoblasts	3
Cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial smooth muscle	3
LRRCA8A and ANO1 contribute to serum-induced VRAC in a Ca2+-dependent manners	3
Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10	3
Combination treatment of perifosine and valsartan showed more efficiency in protecting against pressure overload induced mouse heart failure	3
Targeting L-type amino acid transporter 1 in urological malignancy: Current status and future perspective	3
Comparison of the effects of two anesthetics, isoflurane and urethane, on bladder function in rats	3
Anti-inflammatory and antinociceptive effects of the selective cannabinoid CB2 receptor agonist ABK5	3
Characterization of electropharmacological profile of an anti-atrial fibrillatory drug vernakalant along with potential risk toward torsade de pointes: Translational studies using isoflurane-anestheti	3
The adenosine A2A receptor antagonist/inverse agonist, KW-6356 enhances the anti-parkinsonian activity of L-DOPA with a low risk of dyskinesia in MPTP-treated common marmosets	3
Thrombomodulin induces anti-inflammatory effects by inhibiting the rolling adhesion of leukocytes in vivo	3
Effects of islatravir (4′-ethynyl-2-fluoro-2′-deoxyadenosine or EFdA) on renal tubular cells and islatravir's interactions with organic anion transporters	3
Histamine enhances ATP-induced itching and responsiveness to ATP in keratinocytes	3
Ramelteon administration enhances novel object recognition and spatial working memory in mice	3
2,6-DMBQ suppresses cell proliferation and migration via inhibiting mTOR/AKT and p38 MAPK signaling pathways in NSCLC cells	3
Corrigendum to ‘Schaftoside ameliorates oxygen glucose deprivation-induced inflammation associated with the TLR4/Myd88/Drp1-related mitochondrial fission in BV2 microglia cells’ [J Pharmacol Sci 139 (	3
Purinergic regulation of mast cell function: P2X4 receptor-mediated enhancement of allergic responses	3
NOX1/NADPH oxidase is involved in the LPS-induced exacerbation of collagen-induced arthritis	3
The excitatory effect of hydrogen sulfide on rat colonic muscle contraction and the underlying mechanism	3
Crocetin protects against mitochondrial damage induced by UV-A irradiation in corneal epithelial cell line HCE-T cells	3
The change of the electrophysiological parameters using human intestinal tissues from ulcerative colitis and Crohn's disease	3
Simvastatin attenuates the c-Raf/Erk and calcineurin-NFATc2 pathways via inhibition of Hsp90 activity during the development of heart failure	3