Journal of Pharmacological Sciences

Article	Citations
Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells	83
Re-evaluation of over-the-counter histamine H1-receptor antagonists based on their effects on murine models of allergen-induced nasal hyperresponsiveness	55
Emodin-induced autophagic cell death hinders epithelial–mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis	46
Cystine transporter SLC7A11 regulates sensitivity to unsaturated carbonyl compounds in mouse macrophage cell lines	46
Determination of single-molecule transport activity of OATP2B1 by measuring the number of transporter molecules using electrophysiological approach	35
Research on the protective effect of Rhizoma of Anemarrhena asphodeloides on TMT induced AD mice model based on network pharmacology combined with in vitro and in vivo experimental validation	35
Inorganic sulfides prevent osimertinib-induced mitochondrial dysfunction in human iPS cell-derived cardiomyocytes	31
Potential effective treatment of shortening continuous erythropoietin receptor activator treatment interval combined with iron supplementation in hemodialysis patients	28
Lactate dehydrogenase A inhibition prevents RANKL-induced osteoclastogenesis by reducing enhanced glycolysis	28
Detrusor underactivity causes neurogenic voiding dysfunction in a rat bilateral accessory nerve-injury model	26
Noradrenaline increases intracellular Ca2+ concentration in epithelial cells via α2-adrenoceptors in isolated mouse ileal crypts	26
Quantitative prediction of pharmacokinetic properties of drugs in humans: Recent advance in in vitro models to predict the impact of efflux transporters in the small intestine and blood–brain barrier	24
Analysis of effects of acute hypovolemia on arterial stiffness in rabbits monitored with cardio-ankle vascular index	23
Effects of galantamine on social interaction impairments in cholecystokinin receptor-2 overexpression mice	22
2,6-DMBQ suppresses cell proliferation and migration via inhibiting mTOR/AKT and p38 MAPK signaling pathways in NSCLC cells	21
Sulfur metabolism as a new therapeutic target of heart failure	21
Ramelteon administration enhances novel object recognition and spatial working memory in mice	21
Stathmin expression alters the antiproliferative effect of eribulin in leiomyosarcoma cells	20
Mucin 1 regulates the hypoxia response in head and neck cancer cells	19
Schwann cell derived-peroxiredoxin protects motor neurons against hydrogen peroxide-induced cell death in mouse motor neuron cell line NSC-34	19
Administration of cyclophosphamide to rats induces pica and potentiates 5-hydroxytryptamine synthesis in the intestine without causing severe intestinal injury	19
Role of cardiac α1-adrenoreceptors for the torsadogenic action of IKr blocker nifekalant in the anesthetized atrioventricular block rabbit	18
Microglial depletion exacerbates axonal damage and motor dysfunction in mice with cuprizone-induced demyelination	18
Ibudilast suppresses oxaliplatin-induced mechanical allodynia and neurodegeneration in rats	18
Effects of TND1128 (a 5-deazaflavin derivative), with self-redox ability, as a mitochondria activator on the mouse brain slice and its comparison with β-NMN	17

Involvement of the L-DOPA receptor GPR143 in acute and chronic actions of methylphenidate	17
The influence of OATP2B1 and atorvastatin on coproporphyrin isomers in rats	17
CYP11A1 silencing suppresses HMGCR expression via cholesterol accumulation and sensitizes CRPC cell line DU-145 to atorvastatin	17
In vivo analysis of concentration-dependent effects of halothane or isoflurane inhalation on the electrocardiographic and hemodynamic variables in dogs	16
Impairment of endothelium-dependent vasodilator function of retinal blood vessels in adult rats with a history of retinopathy of prematurity	16
Inhibitory mechanism of tangeretin, a citrus flavone on the sphingosylphosphorylcholine (SPC)-induced vascular smooth muscle contraction	15
Effects of molidustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, on sodium dynamics in hypertensive subtotally nephrectomized rats	15
Novel FABP3 ligand, HY-11-9, ameliorates neuropathological deficits in MPTP-induced Parkinsonism in mice	15
Ameliorating effects of cystine and theanine in a cancer cachexia mouse model	15
T-type Ca2+ channel enhancer SAK3 administration improves the BPSD-like behaviors in AppNL−G-F/NL−G-F knock-in mice	15
Mirogabalin activates the descending noradrenergic system by binding to the α2δ-1 subunit of voltage-gated Ca2+ channels to generate analgesic effects	15
Impact of genetic polymorphisms on the pharmacokinetics and pharmacodynamics of lenvatinib in patients with hepatocellular carcinoma	14
Quinonoid dihydropteridine reductase, a tetrahydrobiopterin-recycling enzyme, contributes to 5-hydroxytryptamine-associated platelet aggregation in mice	14
Peficitinib inhibits fibroblast-like synoviocyte activation and angiogenic vascular endothelial tube formation via inhibitory effects on PDGF and VEGF signaling in addition to JAK	13
Transient receptor potential vanilloid 4 gene-deficiency attenuates the inhibitory effect of 5,6-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid on vascular permeability in mice	13
Influence of light–dark cycle on delayed recovery from isoflurane anesthesia induced by hypnotics in mice	13
Resveratrol promotes autophagosome elimination via SIRT1 in cardiomyocytes	13
Platelet-activating factor (PAF) enhances guinea pig detrusor smooth muscle contractile activities by stimulating voltage-dependent Ca2+ channels and store-operated Ca2+ channels	13
Estrogen decline is a risk factor for paclitaxel-induced peripheral neuropathy: Clinical evidence supported by a preclinical study	12
Granisetron attenuates liver injury and inflammation in a rat model of cecal ligation and puncture-induced sepsis	12
Adipose-specific knockout of ubiquitin-conjugating enzyme E2L6 (Ube2l6) reduces diet-induced obesity, insulin resistance, and hepatic steatosis	12
Safety and efficacy of using cereal food (Frugra®) to improve blood pressure and bowel health in patients undergoing chronic hemodialysis: A pilot study	12
Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells	12
Actions of remimazolam on inhibitory transmission of rat spinal dorsal horn neurons	12
Dencichine prevents ovariectomy-induced bone loss and inhibits osteoclastogenesis by inhibiting RANKL-associated NF-κB and MAPK signaling pathways	12
Supersulfide prevents cigarette smoke extract-induced mitochondria hyperfission and cardiomyocyte early senescence by inhibiting Drp1-filamin complex formation	11
Potential roles of astrocytes and Müller cells in the pathogenesis of glaucoma	11
Neohesperidin exerts antidepressant-like effect via the mechanistic target of rapamycin complex 1 in the medial prefrontal cortex in male mice	11
Calycosin pretreatment enhanced the therapeutic efficacy of mesenchymal stem cells to alleviate unilateral ureteral obstruction-induced renal fibrosis by inhibiting necroptosis	11
Reduced mitochondrial complex II activity enhances cell death via intracellular reactive oxygen species in STHdhQ111 striatal neurons with mutant huntingtin	10
Effects of 17-AAG on the RIP1/RIP3/MLKL pathway during the development of heart failure following myocardial infarction in rats	10
Development of gene silencer pyrrole-imidazole polyamides targeting GSK3β for treatment of polycystic kidney diseases	10
Emodin alleviates lung injury via the miR-217-5p/Sirt1 axis in rats with severe acute pancreatitis	10
Aldo-keto reductase inhibitors increase the anticancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia	10
Sevoflurane induces inflammation of microglia in hippocampus of neonatal rats by inhibiting Wnt/β-Catenin/CaMKIV pathway	10
Atypical antidepressant mirtazapine inhibits 5-hydroxytryptamine3 receptor currents in NCB-20 cells	10
Usefulness and difficulties with the thiopurine pharmacogenomic NUDT15 genotyping test: Analysis of real-world data in Japan	10
Potential treatments of COVID-19: Drug repurposing and therapeutic interventions	10
Blueberry anthocyanins extract attenuated diabetic retinopathy by inhibiting endoplasmic reticulum stress via the miR-182/OGG1 axis	10
Zinc transporters as potential therapeutic targets: An updated review	10
Corrigendum to ‘Nafamostat protects against early brain injury after subarachnoid hemorrhage in mice’ [Journal of Pharmacological Sciences 148 (2022) 65–72]	9
Aronia melanocarpa polysaccharide ameliorates liver fibrosis through TGF-β1-mediated the activation of PI3K/AKT pathway and modulating gut microbiota	9
In vitro and in vivo pharmacological profile of OPC-61815, a water-soluble phosphate ester pro-drug of tolvaptan	9
Analgesic effect of Keishinieppiittokajutsubu on low barometric pressure-induced pain response in arthritic model rats	9
Gallic acid ameliorates endometrial hyperplasia through the inhibition of the PI3K/AKT pathway and the down-regulation of cyclin D1 expression	9
Drug combination of topical ripasudil and brimonidine enhances neuroprotection in a mouse model of optic nerve injury	9
Characterization of remodeling processes in the atria of atrioventricular block dogs: Utility as an early-stage atrial fibrillation model	9
l-DOPA receptor GPR143 inhibits neurite outgrowth via L-type calcium channels in PC12 cells	9
The role of P2Y6 receptor in the pathogenesis of cardiovascular and inflammatory diseases	9
Editorial Board	8

Role of transient receptor potential vanilloid subtype 2 in lower oesophageal sphincter in rat acid reflux oesophagitis	8
Pterostilbene alleviates liver ischemia/reperfusion injury via PINK1-mediated mitophagy	8
N-linoleyltyrosine exerts neuroprotective effects in APP/PS1 transgenic mice via cannabinoid receptor-mediated autophagy	8
The protective effect of Centella asiatica and its constituent, araliadiol on neuronal cell damage and cognitive impairment	8
Imatinib induces diastolic dysfunction and ventricular early-repolarization delay in the halothane-anesthetized dogs: Class effects of tyrosine kinase inhibitors	8
ABCA1 and ABCG1 as potential therapeutic targets for the prevention of atherosclerosis	8
Intrapopulation analysis of longitudinal lifespan in Caenorhabditis elegans identifies W09D10.4 as a novel AMPK-associated healthspan shortening factor	8
Different voltage dependence of ICaL blockade in nonselective IKr blockers causes their opposite effects on early afterdepolarization in drug-induced arrhythmia	8
Human aortic valve interstitial cells obtained from patients with aortic valve stenosis are vascular endothelial growth factor receptor 2 positive and contribute to ectopic calcification	8
Effects of dapagliflozin on peripheral sympathetic nerve activity in standard chow- and high-fat-fed rats after a glucose load	8
Proteasome inhibitors induce apoptosis by superoxide anion generation via NADPH oxidase 5 in human neuroblastoma SH-SY5Y cells	8
Therapeutic effects of the alkaline extract of leaves of Sasa sp. and elucidation of its mechanism in acute kidney injury	7
2,5-Dimethyl-celecoxib induces early termination of inflammatory responses by transient macrophage accumulation and inhibits the progression of cardiac remodeling in a mouse model of cryoinjury-induce	7
Methotrexate mediates the integrity of intestinal stem cells partly through nitric oxide-dependent Wnt/β-catenin signaling in methotrexate-induced rat ileal mucositis	7
Development of hepatic impairment aggravates chemotherapy-induced peripheral neuropathy following oxaliplatin treatment: Evidence from clinical and preclinical studies	7
Perineural treatment with anti-TNF-α antibody ameliorates persistent allodynia and edema in novel mouse models with complex regional pain syndrome	7
Comparison of cytotoxicity of cigarette smoke extract derived from heat-not-burn and combustion cigarettes in human vascular endothelial cells	7
Involvement of TREK1 channels in the proliferation of human hepatic stellate LX-2 cells	7
Paeoniflorin, ferulic acid, and atractylenolide III improved LPS-induced neuroinflammation of BV2 microglia cells by enhancing autophagy	7
Juzentaihoto improves adenine-induced chronic renal failure in BALB/c mice via suppression of renal fibrosis and inflammation	7
The roles of lipid mediators in type I hypersensitivity	7
Effect of antidepressants and social defeat stress on the activity of dorsal raphe serotonin neurons in free-moving animals	6
Platinum-based anticancer drugs-induced downregulation of myosin heavy chain isoforms in skeletal muscle of mouse	6
Preservation of vascular endothelial glycocalyx and barrier by activation of adenosine A2A receptor (A2AR) improved renal dysfunction in cirrhotic rats	6
Oroxylin-A and its phosphonate derivative potentiate eNOS/NO-mediated relaxation and attenuate vasoconstrictor-induced contraction in the mouse aorta	6
Ferulic acid attenuates non-alcoholic steatohepatitis by reducing oxidative stress and inflammation through inhibition of the ROCK/NF-κB signaling pathways	6
A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats	6
Platelet-activating factor contracts guinea pig esophageal muscularis mucosae by stimulating extracellular Ca2+ influx through diltiazem-insensitive Ca2+ channels	6
Tolvaptan induces body fluid loss and subsequent water conservation in normal rats	6
Imeglimin profoundly affects the circadian clock in mouse embryonic fibroblasts	6
Generation of DNA-aptamers targeting galectin-7 for the identification of cholesteatoma residue	6
Aggravation of lipopolysaccharide-induced depressive-like behavior in CCR4-deficient mice	6
The roles of astrocytic phagocytosis in maintaining homeostasis of brains	6
The emerging roles and therapeutic potential of cyclin M/CorC family of Mg2+ transporters	6
Mechanism of canagliflozin-induced vasodilation in resistance mesenteric arteries and the regulation of systemic blood pressure	6
An assessment of the spontaneous locomotor activity of BALB/c mice	6
Simultaneous XIAP and cIAP1/2 inhibition by a dimeric SMAC mimetic AZD5582 induces apoptosis in multiple myeloma	6
Deficiency of interleukin-19 exacerbates acute lung injury induced by intratracheal treatment of hydrochloric acid	6
Penehyclidine hydrochloride activates PARK2 and modulates ubiquitination of AIFM1 to rescue renal tubular injury in diabetic kidney disease	6
Neurotropin® alleviates nerve damage in a mouse chronic nerve compression model	6
Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10	6
Phloroglucinol attenuates oligomeric amyloid beta peptide1-42-induced astrocytic activation by reducing oxidative stress	6
Involvement of endoplasmic reticulum stress in rotenone-induced leber hereditary optic neuropathy model and the discovery of new therapeutic agents	6
Artesunate induces ferroptosis via modulation of p38 and ERK signaling pathway in glioblastoma cells	5
Therapeutic effect of allicin in a mouse model of intracerebral hemorrhage	5
Caffeic acid protects against atherosclerotic lesions and cognitive decline in ApoE−/− mice	5
Evaluation of intracellular signal molecules that regulate TLR4-stimulated inflammatory mediator expression in cultured rat chondrocytes	5
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway	5
Peptides obtained by enzymatic decomposition of mackerel induce recovery from physical fatigue by enhancing the SIRT1-mediated antioxidant effect in the soleus muscle of mice	5
Metformin suppresses epithelial sodium channel hyperactivation and its associated phenotypes in a mouse model of obstructive lung diseases	5
Activation of the angiotensin II receptor promotes autophagy in renal proximal tubular cells and affords protection from ischemia/reperfusion injury	5
Corrigendum to “Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinicepolycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells” [Journa	5
Wilforlide A ameliorates the progression of rheumatoid arthritis by inhibiting M1 macrophage polarization	5
Establishing a high throughput drug screening system for cerebral ischemia using zebrafish larvae	5
Electrophysiological responses to seizurogenic compounds dependent on E/I balance in human iPSC-derived cortical neural networks	5
Amitriptyline and duloxetine attenuate activities of superficial dorsal horn neurons in a rat reserpine-induced fibromyalgia model	5
Presynaptic inhibition of excitatory synaptic transmission from the calcitonin gene-related peptide-containing parabrachial neurons to the central amygdala in mice – unexpected influence of systemic i	5
Andrographolide improves PCP-induced schizophrenia-like behaviors through blocking interaction between NRF2 and KEAP1	5
Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice	5
Targeting enteric glial CRF-R1/Cx43 attenuates stress-induced accelerated colonic motility	5
Evaluation of inhibitory actions of antidepressants on muscarinic receptors assessed by a binding assay in the mouse cerebral neocortex	5
CU06-1004 alleviates oxidative stress and inflammation on folic acid-induced acute kidney injury in mice	5
PP2A regulates metastasis and vasculogenic mimicry formation via PI3K/AKT/ZEB1 axis in non-small cell lung cancers	5
Pharmacological study on the enhancing effects of U46619 on guinea pig urinary bladder smooth muscle contraction induced by acetylcholine and α,β-methylene ATP and the possible involvement of protein	5
Paclitaxel-induced peripheral neuropathy in male rats attenuated by calmangafodipir, a superoxide dismutase mimetic	5
Farrerol suppresses osteoclast differentiation and postmenopausal osteoporosis by inhibiting the nuclear factor kappa B signaling pathway	4
Piezo 1 is involved in intraocular pressure regulation	4
Allyl isothiocyanate, an activator of TRPA1, increases gastric mucosal blood flow through calcitonin gene-related peptide and adrenomedullin in anesthetized rats	4
Comparative characterization of β-adrenoceptors in the bladder, heart, and lungs of rats: Alterations in spontaneously hypertensive rats	4
Repeated topical paeoniflorin attenuates postoperative pain and accelerates cutaneous fibroblast proliferation in mice	4
Camostat mesilate, a serine protease inhibitor, exerts aquaretic effects and decreases urinary exosomal AQP2 levels	4
KCa3.1 regulates cell cycle progression by modulating Ca2+ signaling in murine preosteoblasts	4
Glucocorticoid-induced acute diuresis in rats in relation to the reduced renal expression of sodium-dependent cotransporter genes	4
Combined antiallodynic effects of Neurotropin®–tramadol and Neurotropin®–mirogabalin in rats with L5-spinal nerve ligation	4
Targeting TMEM16A ion channels suppresses airway hyperreactivity, inflammation, and remodeling in an experimental Guinea pig asthma model	4
Icariin alleviates diabetic renal interstitial fibrosis aggravation by inhibiting miR-320a-3p targeting BMP6	4
Sulconazole induces pyroptosis promoted by interferon-γ in monocyte/macrophage lineage cells	4
TPNA10168, an Nrf-2 activator, attenuates inflammatory responses independently of Nrf2 in microglial BV-2 cells: Involvement of the extracellular-signal-regulated kinase pathway	4
Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation	4
Dasatinib suppresses atherosclerotic lesions by suppressing cholesterol uptake in a mouse model of hypercholesterolemia	4

CSF1R inhibitor PLX3397 depletes microglia in Mongolian gerbil Meriones unguiculatus, but not in syrian hamster Mesocricetus auratus	4
Dihydroartemisinin regulates apoptosis, migration, and invasion of ovarian cancer cells via mediating RECK	4
Neuronal activation of nucleus accumbens by local methamphetamine administration induces cognitive impairment through microglial inflammation in mice	4
Minocycline prevents monocrotaline-induced pulmonary hypertension through the attenuation of endothelial dysfunction and vascular wall thickening	4
Insulin-like growth factor 2 promotes osteoclastogenesis increasing inflammatory cytokine levels under hypoxia	4
Long-term glucocorticoid treatment increases CD204 expression by activating the MAPK pathway and enhances modified LDL uptake in murine macrophages	4
Sperm-associated antigen 6 (Spag6) mutation leads to vestibular dysfunction in mice	4
Role of CD34 in calcification of human aortic valve interstitial cells from patients with aortic valve stenosis	4
Protein kinase Cβ is involved in cigarette smoke gas phase-induced ferroptosis in J774 macrophages	4
Laminar-selective spinal astrocyte population capable of converting tactile information into nociceptive in rats	4
Structure-activity relationship studies of pyrogallol as a calcineurin/NFAT signaling suppressor	4
Sestrin2 protects against bavachin induced ER stress through AMPK/mTORC1 signaling pathway in HepG2 cells	4
Extraction and measurement of urinary tetranor-PGDM in disposable diapers	4
Guanabenz inhibits alveolar bone resorption in a rat model of periodontitis	3
Vascular sympathetic neurotransmission and its serotonergic regulation are modified by chronic fluoxetine treatment	3
P2Y2 receptor mediates dying cell removal via inflammatory activated microglia	3
Nafamostat protects against early brain injury after subarachnoid hemorrhage in mice	3
Mitochondrial toxins potentiate hydroxyl radical production in rat striatum during carbon monoxide poisoning	3
Post-stroke treatment with K-134, a phosphodiesterase 3 inhibitor, improves stroke outcomes in the stroke-prone spontaneously hypertensive rat model–A comparative evaluation of antiplatelet drugs	3
Analysis of clinically-reported, memantine-induced cardiovascular adverse responses using the halothane-anesthetized dogs: Reverse translational study	3
Effects of ceramide kinase knockout on lipopolysaccharide-treated sepsis-model mice: Changes in serum cytokine/chemokine levels and increased lethality	3
Histamine enhances ATP-induced itching and responsiveness to ATP in keratinocytes	3
Effect of ASP8062 on morphine self-administration and morphine-induced respiratory suppression in monkeys	3
Circular RNA circPSAP functions as an efficient miR-331-3p sponge to regulate proliferation, apoptosis and bortezomib sensitivity of human multiple myeloma cells by upregulating HDAC4	3
TND1128, a 5-deazaflavin derivative with auto-redox ability, facilitates polarization of mitochondrial membrane potential (ΔΨm) and on-demand ATP synthesis in mice brain slices	3
Protective effects of tadalafil on damaged podocytes in an adriamycin-induced nephrotic syndrome model	3
SARS-CoV-2 induces barrier damage and inflammatory responses in the human iPSC-derived intestinal epithelium	3
Berberine protects cyclophosphamide and busulfan-induced premature ovarian insufficiency in mouse model	3
Orientin reverses acetaminophen-induced acute liver failure by inhibiting oxidative stress and mitochondrial dysfunction	3
LncRNA HOXC-AS1 promotes nasopharyngeal carcinoma (NPC) progression by sponging miR-4651 and subsequently upregulating FOXO6	3
Icariin inhibits epithelial mesenchymal transition of renal tubular epithelial cells via regulating the miR-122-5p/FOXP2 axis in diabetic nephropathy rats	3
Differentiation-inducing factor 1 activates cofilin through pyridoxal phosphatase and AMP-activated protein kinase, resulting in mitochondrial fission	3
circ_0101802 functions as a sponge of miR-1236-3p to facilitate the proliferation, migration and invasion of colorectal cancer via regulating MACC1	3
Opposing functions of α- and β-adrenoceptors in the formation of processes by cultured astrocytes	3
SMTP-44D alleviates diabetic retinopathy by suppressing inflammation and oxidative stress in in vivo and in vitro models	2
Lactucin & Lactucopicrin ameliorates FFA-induced steatosis in HepG2 cells via modulating lipid metabolism	2
The change of the electrophysiological parameters using human intestinal tissues from ulcerative colitis and Crohn's disease	2
Retraction notice to " LncRNA NEAT1 acts as a key regulator of cell apoptosis and inflammatory response by the miR-944/TRIM37 axis in acute lung injury'" [J. Pharmacol. Sci. 145 (2021) 202–212]	2
Alteration of reactivity in isolated mesenteric artery from Zucker fatty diabetes mellitus rats	2
Alpha-linolenic acid selectively inhibits the contraction of pig coronary arteries mediated through prostanoid TP receptors	2
Therapeutic targets in the brain for overactive bladder: A focus on angiotensin II type 1 receptor	2
Effects of islatravir (4′-ethynyl-2-fluoro-2′-deoxyadenosine or EFdA) on renal tubular cells and islatravir's interactions with organic anion transporters	2
Overview for the study of P2 receptors: From P2 receptor history to neuropathic pain studies	2
Taurine deficiency associated with dilated cardiomyopathy and aging	2
Oral administration of MnCl2 attenuated hyperlipidemia-related cardiac remodeling in ApoE−− mice	2
Linalyl acetate as a potential preventive agent against muscle wasting in rheumatoid arthritis rats chronically exposed to nicotine	2
Regulatory action of PGRMC1 on cyclic AMP-mediated COX2 expression in human endometrial cells	2
Role for μ-opioid receptor in antidepressant effects of δ-opioid receptor agonist KNT-127	2
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux	2
Inflammation in the brain and periphery found in animal models of depression and its behavioral relevance	2
Protective effects of paeonol against cognitive impairment in lung diseases	2
Cav3.2-dependent hyperalgesia/allodynia following intrathecal and intraplantar zinc chelator administration in rodents	2
Requirement of the Ca2+ channel β2 subunit for sympathetic PKA phosphorylation	2
EMA401, an angiotensin II type 2 receptor antagonist blocks visceral hypersensitivity and colonic hyperpermeability in rat model of irritable bowel syndrome	2
Pinostrobin inhibits renal CFTR-mediated Cl− secretion and retards cyst growth in cell-derived cyst and polycystic kidney disease rats	2
Identification of tumor-suppressive miRNAs that target amino acid transporter LAT1 and exhibit anti-proliferative effects on cholangiocarcinoma cells	2
Serum stratifin and presepsin as candidate biomarkers for early detection of COVID-19 disease progression	2
Compensatory role of neuregulin-1 in diabetic cardiomyopathy	2
Effects of 1,5-anhydro-D-glucitol on insulin secretion both in in vitro and ex vivo pancreatic preparations	2
Centrally administered butyrate improves gut barrier function, visceral sensation and septic lethality in rats	2
Diverse intracellular signaling pathways mediate the effects of neurotensin on the excitability of type II neurons in the rat dorsolateral bed nucleus of the stria terminalis	2
Goreisan suppresses cardiac remodeling and dysfunction in a new mouse model with diabetic cardiomyopathy	2
Computational study of the therapeutic potentials of a new series of imidazole derivatives against SARS-CoV-2	2
Peficitinib improves bone fragility by recovering bone turnover imbalance in arthritic mice	2
Behavioral changes of food allergic model mice during light and dark period	2
Microglial heterogeneity in aging and Alzheimer's disease: Is sex relevant?	2
Characterization of spinal microglial activation in a mouse model of imiquimod-induced psoriasis	2
Effects of a lysophosphatidic acid receptor 1 antagonist on hypertensive renal injury in Dahl-Iwai salt-sensitive rats	2
MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations	2
Appraisal of ICH E14/S7B Q&As adopted in February 2022 using thorough QT/QTc study data for α4-integrin antagonist carotegrast methyl in Japanese healthy subjects	2
L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy	2
Analyses of the onset mechanisms of cardio-stimulatory action by aciclovir	2
Chronic stress alters lipid mediator profiles associated with immune-related gene expressions and cell compositions in mouse bone marrow and spleen	2
Syntaxin 3 interacts with serotonin transporter and regulates its function	2
Characteristics and therapeutic potential of sodium-dependent phosphate cotransporters in relation to idiopathic basal ganglia calcification	2