Experimental Animals

Article	Citations
Morris water maze: a versatile and pertinent tool for assessing spatial learning and memory	113
Substrains matter in phenotyping of C57BL/6 mice	61
A high-fat diet and high-fat and high-cholesterol diet may affect glucose and lipid metabolism differentially through gut microbiota in mice	39
Infrared thermal imaging associated with pain in laboratory animals	37
Functional analysis of large MAF transcription factors and elucidation of their relationships with human diseases	18
PI3K regulates the activation of NLRP3 inflammasome in atherosclerosis through part-dependent AKT signaling pathway	17
Downregulation of interferon-induced protein with tetratricopeptide repeats 3 relieves the inflammatory response and myocardial fibrosis of mice with myocardial infarction and improves their cardiac f	15
AAV9 transduction mediated by systemic delivery of vector via retro-orbital injection in newborn, neonatal and juvenile mice	13
Protective effects of taxifolin on pazopanib-induced liver toxicity: an experimental rat model	13
The effect of a natural molecule in ovary ischemia reperfusion damage: does lycopene protect ovary?	13
Effects of chitosan oligosaccharides on intestinal oxidative stress and inflammation response in heat stressed rats	13
The status and issues of the Institutional Animal Care and Use Committee of Seoul National University: from its establishment to the present day	13
Tamoxifen feeding method is suitable for efficient conditional knockout	12
Baihui (DU20)-penetrating-Qubin (GB7) acupuncture regulates microglia polarization through miR-34a-5p/<i>Klf4</i> signaling in intracerebral hemorrhage rats	12
Overexpression of miR-224-5p alleviates allergic rhinitis in mice via the TLR4/MyD88/NF-κB pathway	11
Time-restricted feeding prevents high-fat and high-cholesterol diet-induced obesity but fails to ameliorate atherosclerosis in apolipoprotein E-knockout mice	11
miR-145-5p attenuates inflammatory response and apoptosis in myocardial ischemia-reperfusion injury by inhibiting (NADPH) oxidase homolog 1	10
Attenuation of carrageenan-induced hind paw edema and plasma TNF-α level by Philippine stingless bee (<i>Tetragonula biroi</i> Friese) propolis	10
Suppression of ADAM8 attenuates angiotensin II-induced cardiac fibrosis and endothelial-mesenchymal transition via inhibiting TGF-β1/Smad2/Smad3 pathways	9
The potential protective role of folic acid against acetaminophen-induced hepatotoxicity and nephrotoxicity in rats	9
Minocycline attenuates neuronal apoptosis and improves motor function after traumatic brain injury in rats	9
Effect of low-dose ethanol on NLRP3 inflammasome in diabetes-induced lung injury	8
AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment	8
Caffeine: cardiorespiratory effects and tissue protection in animal models	8
Dipeptidyl peptidase-4 inhibition prevents lung injury in mice under chronic stress via the modulation of oxidative stress and inflammation	7

Low maternal licking/grooming stimulation increases pain sensitivity in male mouse offspring	7
Effect of tocilizumab on ischemia-reperfusion-induced oxido-inflammatory renal damage and dysfunction in rats	7
Abietic acid attenuates sepsis-induced lung injury by inhibiting nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway to inhibit M1 macrophage polarization	7
Ultrasonographic study of hemodynamics and contrast-enhanced ultrasound in the rhesus monkey kidney	6
Method for detecting hemodynamic alterations following a single gavage in rats	6
Dementia model mice exhibited improvements of neuropsychiatric symptoms as well as cognitive dysfunction with neural cell transplantation	6
Urinary protein analysis in mice lacking major urinary proteins	6
The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum	6
miR-374 improves cerebral ischemia reperfusion injury by targeting <i>Wnt5a</i>	6
Features of T-cell subset composition in a D-galactose-induced senescence mouse model	6
Tracing location by applying Emerald luciferase in an early phase of murine endometriotic lesion formation	6
Amelioration of oxidative damage parameters by carvacrol on methanol-induced liver injury in rats	5
Suppression of lysosomal-associated protein transmembrane 5 ameliorates cardiac function and inflammatory response by inhibiting the nuclear factor-kappa B (NF-κB) pathway after myocardial infarction	5
A modified mouse model of perioperative neurocognitive disorders exacerbated by sleep fragmentation	5
A novel model mouse for type 2 diabetes mellitus with early onset and persistent hyperglycemia	5
Effect of taxifolin on cyclophosphamide-induced oxidative and inflammatory bladder injury in rats	5
Carbon monoxide ameliorates lipopolysaccharide-induced acute lung injury via inhibition of alveolar macrophage pyroptosis	5
The common marmoset in biomedical research: experimental disease models and veterinary management	5
Female dominance of both spatial cognitive dysfunction and neuropsychiatric symptoms in a mouse model of Alzheimer’s disease	5
Genetic background strongly influences the transition to chronic kidney disease of adriamycin nephropathy in mice	5
Cholinergic- rather than adrenergic-induced sweating play a role in developing and developed rat eccrine sweat glands	5
Intravenous propofol, ketamine (ketofol) and rocuronium after sevoflurane induction provides long lasting anesthesia in ventilated rats	5
Knockdown of histone deacetylase 9 attenuates sepsis-induced myocardial injury and inflammatory response	5
Comparison of survival rates in four inbred mouse strains under different housing conditions: effects of environmental enrichment	4
Novel method for evaluating the health condition of mice in space through a video downlink	4
Influence of high-fat diet on host animal health via bile acid metabolism and benefits of oral-fed <i>Streptococcus thermophilus</i> MN-ZLW-002	4
Generation of a Gal4-dependent gene recombination and illuminating mouse	4
Dexmedetomidine suppresses serum syndecan-1 elevation and improves survival in a rat hemorrhagic shock model	4
A diastolic dysfunction model in non-human primates with transverse aortic constriction	4
Calcium and integrin binding protein 1 (CIB1) induces myocardial fibrosis in myocardial infarction via regulating the PI3K/Akt pathway	4
Calcium carbonate supplementation causes motor dysfunction	4
A reproducible swine model of a surgically created saccular thoracic aortic aneurysm	4
Preventive effect of Ninjin-yoei-to, a Kampo medicine, on amyloid β<sub>1-42</sub>-induced neurodegeneration via intracellular Zn<sup>2+</sup> toxicity in the dentate gyrus	4
Phenotypic and genotypic changes in obesity and type 2 diabetes of male KK mice with aging	4
Comparison of protective effects of hesperetin and pectolinarigenin on high-fat diet-induced hyperlipidemia and hepatic steatosis in Golden Syrian hamsters	4
Inhibition of Kruppel-like factor 7 attenuates cell proliferation and inflammation of fibroblast-like synoviocytes in rheumatoid arthritis through nuclear factor κB and mitogen-activated protein kinas	3
Deficiency of IRG1/ itaconate aggravates endotoxemia-induced acute lung injury by inhibiting autophagy in mice	3
The sirtuin 1 activator SRT1720 alleviated endotoxin-induced fulminant hepatitis in mice	3
Noninvasive monitoring of muscle atrophy and bone metabolic disorders using dual-energy X-ray absorptiometry in diabetic mice	3
Treatment of spontaneously hypertensive rats during pregnancy and lactation with the antioxidant tempol lowers blood pressure and reduces oxidative stress	3
The versatile electric condition in mouse embryos for genome editing using a three-step square-wave pulse electroporator	3
PHF24 is expressed in the inhibitory interneurons in rats	3
MiR-133a-3p inhibits scar formation in scalded mice and suppresses the proliferation and migration of scar derived-fibroblasts by targeting connective tissue growth factor	3
Oroxylin A inhibited autoimmune hepatitis-induced liver injury and shifted Treg/Th17 balance to Treg differentiation	3
Alterations of microRNAs expression profiles in small extracellular vesicle after traumatic brain injury in mice	3
Organoid technology and lung injury mouse models evaluating effects of hydroxychloroquine on lung epithelial regeneration	3
Development of outcome measures according to dystrophic phenotypes in canine X-linked muscular dystrophy in Japan	3
Canine bone marrow peri-adipocyte cells could therapeutically benefit acute spinal cord injury through migration and secretion of hepatocyte growth factor to inflammatory milieu	3
Microbiological survey of Korean mouse facilities from 2014 to 2019	3
Local administration of amyloid enhancing factor initiates <i>in situ</i> amyloid A deposition followed by systemic lesions in mice	3

Possible testosterone redundancy for 5α-dihydrotestosterone in the masculinization of mouse external genitalia	3
Impaired healing of cutaneous wound in a <i>Trpv1</i> deficient mouse	3
Evaluation of different rat models intrauterine adhesion models and improvement of the technique for their establishment	3
Phosphoglycerate kinase (PGK) 1 succinylation modulates epileptic seizures and the blood-brain barrier	3
Dynamics and observations of long-term orthodontic tooth movement and subsequent relapse in C57BL/6 mice	3
Characterization of a bicistronic knock-in reporter mouse model for investigating the role of CABLES2 <i>in vivo</i>	3
Establishment and histopathological study of patient-derived xenograft models and primary cell lines of epithelioid malignant peritoneal mesothelioma	3
Disruption of testis-enriched cytochrome c oxidase subunit COX6B2 but not COX8C leads to subfertility	3
A complete heart regeneration model with inflammation as a key component	3
Impacts of ceftriaxone exposure during pregnancy on maternal gut and placental microbiota and its influence on maternal and offspring immunity in mice	3
Generation of <i>c-Fos</i> knockout rats, and observation of their phenotype	3
MRI metrics at the epicenter of spinal cord injury are correlated with the stepping process in rhesus monkeys	3
Comparison of the wound-healing efficacy of gelatin sponge dressings and that of artificial dermis using atelocollagen in a rat cranial periosteal defect model	2
The past and present of therapeutic strategy for Alzheimer’s diseases: potential for stem cell therapy	2
Neuroprotective effect of gallic acid in mice with rotenone-induced neurodegeneration	2
Establishment of a human microbiome- and immune system-reconstituted dual-humanized mouse model	2
The Kruppel-like factor 4-signal transducer and activator of transcription 5A axis promotes pancreatic fibrosis in mice with caerulein-induced chronic pancreatitis	2
Effects of taxifolin on aspirin-induced gastric damage in rats: macroscopic and biochemical evaluation	2
A novel, simplified, and reproducible porcine model of acute ischemic liver failure with portal vein preservation	2
Mitochondrial DNA deletion-dependent podocyte injuries in Mito-miceΔ, a murine model of mitochondrial disease	2
The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflam	2
Humanized CD36 (hCD36) mouse model supports the preclinical evaluation of therapeutic candidates targeting CD36	2
The testis-, epididymis-, or seminal vesicle-enriched genes <i>Aldoart2</i>, <i>Serpina16</i>, <i>Aoc1l3</i>, and <i>Pate14</i> are not essential for ma	2
Characterization of single nucleotide polymorphisms for a forward genetics approach using genetic crosses in C57BL/6 and BALB/c substrains of mice	2
Retinal Src homology region 2-containing protein tyrosine phosphatase 2 silencing alleviates diabetic retinopathy via suppressing inflammatory response and oxidative stress by regulating Yes-associate	2
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model	2
Generation of avian-derived anti-B7-H4 antibodies exerts a blockade effect on the immunosuppressive response	2
Granulocyte colony-stimulating factor protected against brain injury in a rat cerebral hemorrhage model by modulating inflammation	2
Effects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive rats	2
Estrogen synthesis in the stomach of Sprague-Dawley rats: comparison to Wistar rats	2
Expression of CCDC85C, a causative protein for hydrocephalus, and intermediate filament proteins during lateral ventricle development in rats	2
Sirtuin3 confers protection against acute pulmonary embolism through anti-inflammation, and anti-oxidative stress, and anti-apoptosis properties: participation of the AMP-activated protein kinase/mamm	2
Anti-inflammatory effect of HGF responses to oral traumatic ulcers using an HGF-Tg mouse model	2
Creation of an experimental rearing environment for microbiome animal research using an individually ventilated cage system and bioBUBBLE enclosure	2
A controlled ovarian stimulation procedure suitable for cynomolgus macaques	2
2,4,6-trinitrobenzenesulfonic acid-induced colitis in <i>Rattus norgevicus</i>: a categorization proposal	2
Human disease-associated extracellular matrix orthologs ECM3 and QBRICK regulate primary mesenchymal cell migration in sea urchin embryos	2
An L314Q mutation in <i>Map3k1</i> gene results in failure of eyelid fusion in the N-ethyl-N-nitrosourea-induced mutant line	2
Age-related changes in lung function in National Center for Geriatrics and Gerontology Aging Farm C57BL/6N mice	2
Pathogenesis of murine astrovirus in experimentally infected mice	2
Repair of brain damage size and recovery of neurological dysfunction after ischemic stroke are different between strains in mice: evaluation using a novel ischemic stroke model	2
Establishment and application of a lethal model of an HRSV-long variant strain in BALB/c mice	2
Leucine rich repeat containing 32 accelerates tenogenic differentiation of tendon-derived stem cells and promotes Achilles tendon repair in rats	1
Cardiorenal damages in mice at early phase after intervention induced by angiotensin II, nephrectomy, and salt intake	1
Eriocalyxin B alleviated ischemic cerebral injury by limiting microglia-mediated excessive neuroinflammation in mice	1
Intraplacental injection of AAV9-CMV-iCre results in the widespread transduction of multiple organs in double-reporter mouse embryos	1
The grimace scale: a useful tool for assessing pain in laboratory animals	1
Whole blood transfusion in common marmosets: a clinical evaluation	1
The Philippines stingless bee propolis promotes hair growth through activation of Wnt/β-catenin signaling pathway	1
Effects of two weeks of food restriction on toxicological parameters in cynomolgus monkeys	1
Drastic hypothermia after intraperitoneal injection of okadaic acid, a diarrhetic shellfish poisoning toxin, in mice	1
Effects of oxygen tension and humidity on the preimplantation development of mouse embryos produced by <i>in vitro</i> fertilization: analysis using a non-humidifying incubator with time-l	1
The establishment and application of CD3E humanized mice in immunotherapy	1
The cerebral artery in cynomolgus monkeys (<i>Macaca fascicularis</i>)	1
Tensin 2-deficient nephropathy: mechanosensitive nephropathy, genetic susceptibility	1
Renal transcriptome analysis of uninephrectomized <i>db/db</i> mice identified a mechanism for the transition to severe diabetic nephropathy	1
Retraction: Effect of Treadmill Exercise on Bone Mass in Female Rats	1
Effect of Cetrorelix administration on ovarian stimulation in aged mice	1
Eliminating murine norovirus, <i>Helicobacter hepaticus</i>, and intestinal protozoa by embryo transfer for an entire mouse barrier facility	1
New murine model of alcoholic hepatitis in obesity-induced metabolic-associated fatty liver disease	1
Loss of AKAP12 aggravates rheumatoid arthritis-like symptoms and cardiac damage in collagen-induced arthritis mice	1
Comparison of the anatomical morphology of cervical vertebrae between humans and macaques: related to a spinal cord injury model	1
MicroRNA-363-3p/sphingosine-1-phosphate receptor 1 axis inhibits sepsis-induced acute lung injury via the inactivation of nuclear factor kappa-B ligand signaling	1
L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model	1
Generation of the Y-chromosome linked red fluorescent protein transgenic mouse model and sexing at the preimplantation stage	1
Validation of the anesthetic effect of a mixture of remimazolam, medetomidine, and butorphanol in three mouse strains	1
Construction of a canine model with acute type B aortic dissection using a self-made pressure-driven flow device	1
Anatomy and nomenclature of tree shrew lymphoid tissues	1
Ivabradine ameliorates cardiomyopathy progression in a Duchenne muscular dystrophy model rat	1
Differences in exercise capacity and muscle glycogen metabolism in C57BL/6J and BALB/cA mice	1
A 3-Mbp fragment on rat chromosome 1 affects susceptibility both to stroke and kidney injury under salt loading in the stroke-prone spontaneously hypertensive rat: a genetic approach using multiple co	1
Effect of felodipine on indomethacin-induced gastric ulcers in rats	1
Neuroprotective effects of betanin in mice with cerebral ischemia-reperfusion injury	1
SRY-box transcription factor 9 modulates Müller cell gliosis in diabetic retinopathy by upregulating TXNIP transcription	1
FERM domain containing kindlin 1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLR family pyrin domain containing 3/nuclear factor kappa B pathway	1
Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression	1
A novel ENU-induced <i>Cpox</i> mutation causes microcytic hypochromic anemia in mice	1
JM-1232(−) and propofol, a new combination of hypnotics with short-acting and non-cumulative preferable properties	1
Apolipoprotein E-depletion accelerates arterial fat deposition in the spontaneously hypertensive rat	1
Middle aged CAMKII-Cre:<i>Cbs<sup>fl/fl</sup></i> mice: a new model for studying perioperative neurocognitive disorders	1

Establishment of a novel method for the production of chimeric mouse embryos using water-in-oil droplets	1
Differences in exercise capacity and physiological responses in Wistar rats among breeders	1
Symposium 4	0
Symposium 5	0
Symposium 8	0
Complement C3 deficient mice show more severe imiquimod-induced psoriasiform dermatitis than wild-type mice regardless of the commensal microbiota	0
Breeding and Lineage development	0
Symposium 5	0
Inhibition of TRAF6 alleviates secondary brain injury by reducing neuronal pyroptosis after intracerebral hemorrhage	0
The Chinese hamster as an excellent experimental animal model	0
A novel abdominal aortic aneurysm model produced by periarterial application of hydrochloric acid	0
<i>Cyba</i> and <i>Nox2</i> mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner	0
Poster Presentation	0
LAS Seminar 2	0
Null mutation of exocyst complex component 3-like does not affect vascular development in mice	0
International Award	0
Genetics, Selective Breeding and Gene Function	0
Generation of reporter mice for detecting the transcriptional activity of nuclear factor of activated T cells	0
Effects of Angiotensin II type I receptor shRNA on blood pressure and left ventricular remodeling in spontaneously hypertensive rats	0
Encouragement Award	0
Time-dependent changes in retinoids content in liver and adipose tissue after feeding of a vitamin A-deficient diet to mice	0
Symposium 8	0
Poster Presentation	0
Microorganisms, Infection and Immunity	0
Oral Presentation (Best Presentation Award)	0
Loss of N-acetylglucosaminyl transferase V is involved in the impaired osteogenic differentiation of bone marrow mesenchymal stem cells	0
Positional cloning of rat mutant genes reveals new functions of these genes	0
Brain, Neurology and Behavior	0
Establishment of a novel experimental system using single cell-derived pleomorphic rhabdomyosarcoma cell lines expressing K-RasG12V and deficient in p53	0
Symposium 7	0
Symposium 6	0
LAS Seminar 1	0
Identification of gene mutations associated with the phenotype of short-limb mice emerging from a foundation colony of severely immunodeficient mice	0
A wild-derived inbred mouse strain, MSM/Ms, provides insights into novel skin tumor susceptibility genes	0
Poster Presentation	0
Development of incident severity classification for laboratory animals	0
Symposium 3	0
Moderate hyperglycemia suppresses melanoma metastasis to liver	0
Endothelial GATA3 is involved in coagulofibrinolytic homeostasis during endotoxin sepsis	0
International Award	0
A novel electroencephalographic evaluation of noxious stimulation during isoflurane anesthesia in dogs	0
Ando-Tajima Award	0
Experimental Technique, Substitution, Anesthesia and Analgesia	0
Downregulation of High mobility group box 2 relieves spinal cord injury by inhibiting microglia-mediated neuroinflammation	0
Protective effect of 8-Gingerol, a potent constituent of ginger, on acute lung injury following hemorrhagic shock in rats	0
EDA2R knockdown alleviates myocardial ischemia/reperfusion injury through inhibiting the activation of the NF-κB signaling pathway	0
Functional role of IL-19 in a mouse model of L-arginine-induced pancreatitis and related lung injury	0
Symposium 2	0
Oral Presentation	0
A fast and simple protocol to anaesthesia in chicken embryos	0
Symposium 1	0
Deletion of <i>Exoc7</i>, but not <i>Exoc3</i>, in male germ cells causes severe spermatogenesis failure with spermatocyte aggregation in mice	0
Disease models	0
Symposium 7	0
Aging	0
Symposium 2	0
Transmembrane p24 trafficking protein 10 (TMED10) inhibits mitochondrial damage and protects neurons in ischemic stroke via the c-Jun N-terminal kinase (JNK) signaling pathway	0
Education Seminar	0
Symposium 3	0
Educational Lecture	0
Symposium 8	0
Other Classification	0
LAS Seminar 3	0
Plenary Lecture 2	0
Pharmacology and Safety	0
Systemic autoimmune abnormalities alter the morphology of mucosa-associated lymphoid tissues in the rectum of MRL/MpJ-<i>Fas<sup>lpr/lpr</sup></i> mice	0
Plenary Lecture	0
Symposium 4	0
Melinjo (<i>Gnetum gnemon L.</i>) seed extract for treatment of sleep/wake fragmentation in diet-induced obese mice	0
Optimization of inhaled anesthesia for <i>Octodon degus</i> using electroencephalography	0
Administration of lipid emulsion reduced the hypnotic potency of propofol more than that of thiamylal in mice	0
Effects of intravenous infusion, vest wearing and repeated intravenous blood collection on clinical pathology parameters in cynomolgus monkeys (<i>Macaca fascicularis</i>)	0
Symposium 2	0
Errata: Osthole improves therapy for osteoporosis through increasing autophagy of mesenchymal stem cells	0
Dosage and organic acid residue of MOG<sub>35-55</sub> peptide influences immunopathology and development of BCG induced experimental autoimmune encephalomyelitis (EAE)	0
Symposium 3	0
Annual two-dose tetanus toxoid vaccination induces protective humoral immunity to all age groups of rhesus macaques	0
Automated scoring of glomerular injury in TNS2-deficient nephropathy	0
Nutrition, Physiology and Biochemistry	0
Special Lecture	0
Progranulin deficiency attenuates tubulointerstitial injury in a mouse unilateral ureteral obstruction model	0
Ando-Tajima Award	0
Involvement of gut microbiota recovery and autophagy induction in Youhua Kuijie Formula’s protection against experimental ulcerative colitis	0
UBL4A alleviates the progression of intracerebral hemorrhage by regulating oxidative stress and mitochondrial damage	0
Symposium 1	0
Symposium 7	0
Targeted proteomic analysis reveals that crocodile oil from <i>Crocodylus siamensis</i> may enhance hepatic energy metabolism in rats	0
Management, Facilities, Ethics and Welfare	0
Differences in susceptibility to ADR nephropathy among C57BL/6 substrains	0
Encouragement Award	0
Encouragement Award	0
LAS Seminar 2	0
Errata: Middle aged CAMKII-Cre:<i>Cbs<sup>fl/fl</sup></i> mice: a new model for studying perioperative neurocognitive disorders	0
LAS Seminar 2	0
The acoustic startle reflex as a tool for assessment of odor environment effects on affective states in laboratory mice	0