Experimental Animals

Article	Citations
Symposium 2	22
Administration of lipid emulsion reduced the hypnotic potency of propofol more than that of thiamylal in mice	18
L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model	17
Identification of gene mutations associated with the phenotype of short-limb mice emerging from a foundation colony of severely immunodeficient mice	17
Disruption of testis-enriched cytochrome c oxidase subunit COX6B2 but not COX8C leads to subfertility	13
Dosage and organic acid residue of myelin oligodendrocyte glycoprotein<sub>35–55</sub> peptide influences immunopathology and development of Bacillus Calmette-Guérin induced experimental a	12
Symposium 7	12
Symposium 8	12
D-galactose treatment accumulates AGEs but induces no further detrimental effects in HR-1 mouse skin	12
Treatment of spontaneously hypertensive rats during pregnancy and lactation with the antioxidant tempol lowers blood pressure and reduces oxidative stress	12
Oral Presentation	11
Dual specificity protein phosphatase 5, transcriptionally inhibited by SRY-box transcription factor 11, inhibits T helper 2 differentiation in CD4<sup>+</sup> T cells: a	11
Symposium 1	11
Dual-route administration of balanced anesthesia using medetomidine, midazolam, and butorphanol provides both suitable anesthetic depth and reduced tissue injury in rabbits	11
Effect of gamma-ray exposure on the genome-editing efficiency of improved genome-editing via oviductal nucleic acids delivery (<i>i</i>-GONAD)	11
New murine model of alcoholic hepatitis in obesity-induced metabolic-associated fatty liver disease	11
Plenary Lecture 2	10
Therapeutic potential of omentin-1 in preeclampsia: enhancing fetal outcomes, vascular function, and reducing inflammation	10
Symposium 2	9
Symposium 2	9
Ando-Tajima Award	9
Optimization of culture-preservation methods to maintain developmental competence in porcine metaphase II (MII) oocytes post-<i>in vitro</i> maturation (IVM)	9
Optimization of inhaled anesthesia for <i>Octodon degus</i> using electroencephalography	8
Effect of felodipine on indomethacin-induced gastric ulcers in rats	8
Progranulin deficiency attenuates tubulointerstitial injury in a mouse unilateral ureteral obstruction model	8

Time-dependent changes in retinoids content in liver and adipose tissue after feeding of a vitamin A-deficient diet to mice	7
AltEx-BE: a tool for designing splice-site-targeting gRNAs for base editing-mediated exon skipping with exon-level annotations in diverse experimental animals	7
Loss of TMC7 causes male infertility with disrupted spermiogenesis in mice	7
A novel miniTurbo knock-in mouse reveals a protein interaction network of USP46 in the brain	7
Plenary Lecture 3	7
Diverse Cre recombinase expression pattern in Albumin-Cre driver rats	7
Targeted proteomic analysis reveals that crocodile oil from <i>Crocodylus siamensis</i> may enhance hepatic energy metabolism in rats	6
Resveratrol alleviates endometriosis via restoration of hypoxic milieu and inhibition of autoantibody deposition	6
Carbon monoxide ameliorates lipopolysaccharide-induced acute lung injury via inhibition of alveolar macrophage pyroptosis	6
Birth of offspring derived from cryopreserved rat sperm after shipment in a Styrofoam box at −80°C	6
A survey of the impact of COVID-19 on the management of animal experiments and laboratory animal facilities in Korea	6
Symposium 2	6
Double-decker cage reduces mount frequency and ejaculation latency, resulting in reduced weight loss in male rats after mating behavior	6
Symposium 5	6
LAS Seminar 3	6
Tensin2 deficiency transiently accelerates early-phase regenerative myofiber growth following cardiotoxin-induced injury in mice	6
Circadian and sleep phenotypes in a mouse model of Alzheimer’s disease characterized by intracellular accumulation of amyloid β oligomers	6
Stingless bee propolis promotes hair follicle regeneration and melanocyte function in chemotherapy-induced alopecia mouse model	6
A viral FLIP protein, E8, exogenously-expressed in the mesenchymal lineage of mice leads to bone malformations, lipoatrophy, and muscular atrophy	5
International Award	5
Rescue of oocytes recovered from postmortem mouse ovaries	5
Daphnetin ameliorates diabetic cardiomyopathy by regulating inflammation and endoplasmic reticulum stress-induced apoptosis	5
Loss of non-canonical translation initiation factors impairs perinatal cardiac function in mice	5
Plenary Lecture 2	5
Menstrual cycles, lifespan, and anti-Müllerian hormone in cynomolgus monkeys	4
Poster Presentation	4
Downregulation of High mobility group box 2 relieves spinal cord injury by inhibiting microglia-mediated neuroinflammation	4
Poster Presentation	4
Endothelial GATA3 is involved in coagulofibrinolytic homeostasis during endotoxin sepsis	4
Plenary Lecture 1	4
Apolipoprotein E-depletion accelerates arterial fat deposition in the spontaneously hypertensive rat	4
Symposium 6	4
A novel non-transecting ligation technique for clinically mimetic cholestatic cirrhosis in rats	4
Deletion of <i>Exoc7</i>, but not <i>Exoc3</i>, in male germ cells causes severe spermatogenesis failure with spermatocyte aggregation in mice	4
Inhibition of tumor necrosis factor receptor-associated factor 6 alleviates secondary brain injury by reducing neuronal pyroptosis after intracerebral hemorrhage	4
Systemic autoimmune abnormalities alter the morphology of mucosa-associated lymphoid tissues in the rectum of MRL/MpJ-<i>Fas<sup>lpr/lpr</sup></i> mice	4
Oral Presentation (Best Presentation Award)	4
Annual two-dose tetanus toxoid vaccination induces protective humoral immunity to all age groups of rhesus macaques	4
Positional cloning of rat mutant genes reveals new functions of these genes	4
Symposium 4	4
PacBio long-read amplicon sequencing of dog leukocyte antigen genes at full-length level in beagle dogs	3
The Chinese hamster as an excellent experimental animal model	3
Nucleic acid sensing Toll-like receptors 3 and 9 play complementary roles in the development of bacteremia after nasal colonization associated with influenza co-infection	3
Phosphoglycerate kinase (PGK) 1 succinylation modulates epileptic seizures and the blood-brain barrier	3
Repeated surgical oocyte collection from severe immunodeficient NOG mice after repeated superovulation with inhibin antiserum and eCG	3
DNA repair protein RAD50 is involved in the streptozotocin-induced diabetes susceptibility of mice	3
Biological characteristics of age-related changes in C57BL/6 mice sub-strains in the national center for geriatrics and gerontology aging farm	3
Post stress sensory contact with a male mouse is associated with altered social behavior in a female vicarious social defeat stress model	3
A modified mouse model of perioperative neurocognitive disorders exacerbated by sleep fragmentation	3
Honghe Fujie lotion ameliorates pregnancy-associated vulvovaginal candidiasis in mice by inhibiting the activation of NLRP3 inflammasome	3

Automated scoring of glomerular injury in TNS2-deficient nephropathy	3
Differences in exercise capacity and muscle glycogen metabolism in C57BL/6J and BALB/cA mice	3
Generation of mice expressing liver-specific fluorescent genes and the optimal conditions for signal detection via <i>in vivo</i> imaging	3
Comparative study of renal filtration barrier structure and key gene expression between <i>Lepus yarkandensis</i> and <i>Oryctolagus cuniculus</i>	3
Enhancing the neural differentiation capabilities of genetically asymmetric mouse F1 hybrid embryonic stem cell lines	3
Exposure to xylene early in life induces memory abnormalities of adult male mice	2
The usefulness of HbA1c measurement in diabetic mouse models using various devices	2
Body weight loss without reduction in food consumption observed in cynomolgus monkeys during non-clinical toxicity studies	2
Plenary Lecture 1	2
Integrative network pharmacology and experimental study of Qingda granule in hypertension-induced endothelial dysfunction	2
Oral Presentation (Best Presentation Award)	2
Impaired healing of cutaneous wound in a <i>Trpv1</i> deficient mouse	2
Errata: Middle aged CAMKII-Cre:<i>Cbs<sup>fl/fl</sup></i> mice: a new model for studying perioperative neurocognitive disorders	2
Contrasting effects of PHD finger protein 24 (PHF24) on brain morphology of the spontaneous generalized tonic-clonic seizure model; Noda epileptic rat (NER) and <i>Phf24</i>-null rat	2
Symposium 4	2
Symposium 4	2
Comparison of retinal parameters between rhesus and cynomolgus macaques	2
Reference intervals for hematologic and biochemical values in Cynomolgus monkeys from different breeding populations in China	2
Neu5Ac promotes high-fat diet-induced progression of atherosclerosis in <i>ApoE</i>-deficient mice	2
Symposium 3	2
Morphological analysis of autophagy in axonal degeneration in gracile axonal dystrophy mice	2
Plenary Lecture 1	2
An efficient evaluation system for factors affecting the genome editing efficiency in mouse	2
The rat Downunder (<i>Du</i>) coat color mutation is associated with eye anomalies and embryonic lethality and maps to a 3.9-Mb region on chromosome 3	2
The grimace scale: a useful tool for assessing pain in laboratory animals	1
Null mutation of exocyst complex component 3-like does not affect vascular development in mice	1
Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression	1
Establishment and visual analysis of CBA/J-<i>Pde6b<sup>Y347Y/Y347X</sup></i> and C3H/HeJ-<i>Pde6b<sup>Y347Y/Y347X</sup></i> mice	1
Leucine rich repeat containing 32 accelerates tenogenic differentiation of tendon-derived stem cells and promotes Achilles tendon repair in rats	1
The testis-, epididymis-, or seminal vesicle-enriched genes <i>Aldoart2</i>, <i>Serpina16</i>, <i>Aoc1l3</i>, and <i>Pate14</i> are not essential for ma	1
Oral Presentation (Best Presentation Award)	1
Deficiency of IRG1/ itaconate aggravates endotoxemia-induced acute lung injury by inhibiting autophagy in mice	1
Effects of intravenous infusion, vest wearing and repeated intravenous blood collection on clinical pathology parameters in cynomolgus monkeys (<i>Macaca fascicularis</i>)	1
Symposium 1	1
Encouragement Award	1
Histidine and soy isoflavones co-ingestion induces browning of white adipose tissue and promotes lipolysis in female rats	1
Generation of reporter mice for detecting the transcriptional activity of nuclear factor of activated T cells	1
Royal jelly reduced non-rapid eye movement sleep fragmentation and restored sleep stability in diet-induced obese mice	1
Transient receptor potential vanilloid 1 interacts with Toll-like receptor 4 (TLR4)/cluster of differentiation 14 (CD14) signaling pathway in lipopolysaccharide-mediated inflammation in macrophages	1
Symposium 3	1
Ando-Tajima Award	1
Symposium 1	1
Encouragement Award	1
Special Lecture	1
Electroacupuncture improves cognitive function in high-fat diet/streptozocin-induced type 2 diabetic mice by inhibiting autophagy-related ferroptosis	1
Poster Presentation	1
LAS Seminar 1	1
Dynamics and observations of long-term orthodontic tooth movement and subsequent relapse in C57BL/6 mice	1
Canine regional gastric blood flow measurement using perfusion computed tomography	1
SRY-box transcription factor 9 modulates Müller cell gliosis in diabetic retinopathy by upregulating TXNIP transcription	1
Clodronate liposome treatment contributes to the nerve regeneration in corneal nerve involvement of diabetic mice	0
LAS Seminar 2	0
Ubiquitin-like 4A alleviates the progression of intracerebral hemorrhage by regulating oxidative stress and mitochondrial damage	0
Involvement of CD72 in membranoproliferative glomerulonephritis induced by <i>Plasmodium chabaudi</i> AS infection in NC/Jic mice	0
Establishment of a novel experimental system using single cell-derived pleomorphic rhabdomyosarcoma cell lines expressing K-RasG12V and deficient in p53	0
Symposium 6	0
A fast and simple protocol to anaesthesia in chicken embryos	0
A novel electroencephalographic evaluation of noxious stimulation during isoflurane anesthesia in dogs	0
Keratinocyte-specific STAT3 knockout attenuates imiquimod-induced psoriasiform phenotype in mice	0
Hematologic and biochemical changes associated with age and strain in aged B6 mice breeding in the national center of geriatrics and gerontology	0
Knockdown of histone deacetylase 9 attenuates sepsis-induced myocardial injury and inflammatory response	0
Oral Presentation	0
Young Investigator Award	0
T cell transfer into immunodeficient mice uncovers a paralytic phenotype beyond colitis	0
Lonicerin alleviates ovalbumin-induced asthma of mice <i>via</i> inhibiting enhancer of zeste homolog 2/nuclear factor-kappa B signaling pathway	0
Plenary Lecture 1	0
Intron polymorphism in <i>Camk2d</i> is associated with ventricular arrhythmias in normal adult Sprague-Dawley rats	0
<i>Cyba</i> and <i>Nox2</i> mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner	0
Early-stage therapeutic efficacy of TNAP inhibition using a novel milder murine model of CKD-MBD	0
Mouse NOD/Shi and NSY/Hos strains infected with <i>Plasmodium berghei</i> ANKA are models for experimental cerebral malaria	0
Dehydroepiandrosterone modulates the PTEN/PI3K/AKT signaling pathway to alleviate 4-vinylcyclohexene diepoxide-induced premature ovarian insufficiency in rats	0
FERM domain containing kindlin 1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLR family pyrin domain containing 3/nuclear factor kappa B pathway	0
Autologous transplantation of green tea epigallocatechin-3-gallate pretreated adipose-derived stem cells increases cardiac regenerative capability through C-X-C motif chemokine receptor 4 expression i	0
Effects of sex hormones on the development of diabetes and pancreatic islet gene expression in obese type 2 diabetes model ZFDM rat	0
Effects of aging and reproductive history on bone parameters of common marmoset (<i>Callithrix jacchus</i>) mandibles	0
A novel abdominal aortic aneurysm model produced by periarterial application of hydrochloric acid	0
Ring finger protein 10 is atherosclerosis protective and modulates macrophage polarization	0
Resistance against the development of diethylnitrosamine-induced hepatocellular carcinoma in female C3H mice: an experimental model	0
Dual-route medetomidine-alfaxalone-butorphanol anesthesia: a refined protocol for balanced anesthesia in male rabbits	0
Adriamycin-induced nephropathy models: elucidating CKD pathophysiology and advancing therapeutic strategies	0

Effects of two weeks of food restriction on toxicological parameters in cynomolgus monkeys	0
Melinjo (<i>Gnetum gnemon</i> L.) seed extract for treatment of sleep/wake fragmentation in diet-induced obese mice	0
Suppression of USP2 in mouse skeletal muscle: a model of oxidative stress in muscle tissue	0
Diacerein alleviates endometrial fibrosis in an intrauterine adhesion model via ferroptosis inhibition	0
The compensatory increase of Gli-similar 3 inhibited neuronal apoptosis through regulating Mps one binder kinase activator 1b (MOB1b): a possible strategy for the functional recovery after spinal cord	0
Local administration of amyloid enhancing factor initiates <i>in situ</i> amyloid A deposition followed by systemic lesions in mice	0
Andoh-Tajima Award	0
A nonsense mutation in the <i>Mocos</i> gene induces xanthinuria, obstructive nephropathy, and anemia in rats	0
Oral Presentation (Best Presentation Award)	0
Symposium 6	0
Dominant effect of a single amino acid mutation in the motor domain of myosin VI on hearing in mice	0
Trophectoderm-specific gene manipulation using adeno-associated viral vectors	0
Effects of taxifolin on aspirin-induced gastric damage in rats: macroscopic and biochemical evaluation	0
Symposium 3	0
Symposium 4	0
Comparison of the characteristics of non-alcoholic fatty liver disease in C57BL/6J-<i>Lepr<sup>em1hwl</sup></i>/Korl and C57BLKS/J-<i>Lepr<sup>db</sup></i&	0
Transferrin receptor knockdown attenuates atrial fibrillation by inhibiting cardiomyocyte ferroptosis and atrial fibrosis	0
The Kruppel-like factor 4-signal transducer and activator of transcription 5A axis promotes pancreatic fibrosis in mice with caerulein-induced chronic pancreatitis	0
The past and present of therapeutic strategy for Alzheimer’s diseases: potential for stem cell therapy	0
Symposium 9	0
The <i>peroneal muscular atrophy</i> mouse<i></i>has aberrant projection of spinal motor axons to the gluteal region	0
Functional behavioral profiling of multiple Cre-driver rat lines	0
Poster Presentation	0
Symposium 7	0
Symposium 1	0
Symposium 8	0
Neuroprotective effect of gallic acid in mice with rotenone-induced neurodegeneration	0
Long-term application of MC903 in mice prolongs the characteristic symptoms of atopic dermatitis, such as inflammation, skin barrier dysfunction, and itching	0
Exploring the role of zolpidem in alleviating cognitive and motor impairments in chronic cerebral hypoperfusion: a rat model study with <i>in vivo</i> and <i>in silico</i> insi	0
Time course of histopathology of bleomycin-induced pulmonary fibrosis using an intratracheal sprayer in mice	0
Sirtuin3 confers protection against acute pulmonary embolism through anti-inflammation, and anti-oxidative stress, and anti-apoptosis properties: participation of the AMP-activated protein kinase/mamm	0
Open Public Lecture	0
Disruption of intestinal barrier and dysbiosis of gut microbiota in an experimental rhesus macaque model with 6-year diabetes mellitus	0
Renal transcriptome analysis of uninephrectomized <i>db/db</i> mice identified a mechanism for the transition to severe diabetic nephropathy	0
The Philippines stingless bee propolis promotes hair growth through activation of Wnt/β-catenin signaling pathway	0
Non-invasive individual identification of adult <i>Pleurodeles waltl</i> using Deep Learning	0
Ivabradine ameliorates cardiomyopathy progression in a Duchenne muscular dystrophy model rat	0
RNA-Seq analysis of obese <i>Pdha1<sup>fl/fl</sup></i>Lyz2-Cre mice induced by a high-fat diet	0
Nicardipine co-administered with medetomidine-midazolam-butorphanol anesthesia attenuates post-anesthetic hypothermia in rats	0
Noninvasive monitoring of muscle atrophy and bone metabolic disorders using dual-energy X-ray absorptiometry in diabetic mice	0
Transmembrane p24 trafficking protein 10 (TMED10) inhibits mitochondrial damage and protects neurons in ischemic stroke via the c-Jun N-terminal kinase (JNK) signaling pathway	0
Oral Presentation	0
Relationship between aging and periodontal disease severity in gauge-raised cynomolgus monkeys (<i>Macaca fascicularis</i>)	0
Comparison of protective effects of hesperetin and pectolinarigenin on high-fat diet-induced hyperlipidemia and hepatic steatosis in Golden Syrian hamsters	0
Canine bone marrow peri-adipocyte cells could therapeutically benefit acute spinal cord injury through migration and secretion of hepatocyte growth factor to inflammatory milieu	0
Genetic background strongly influences the transition to chronic kidney disease of adriamycin nephropathy in mice	0
Intraplacental injection of AAV9-CMV-iCre results in the widespread transduction of multiple organs in double-reporter mouse embryos	0
Evaluation of different rat models intrauterine adhesion models and improvement of the technique for their establishment	0
Complement C3 deficient mice show more severe imiquimod-induced psoriasiform dermatitis than wild-type mice regardless of the commensal microbiota	0
Ectodysplasin-A2 receptor (EDA2R) knockdown alleviates myocardial ischemia/reperfusion injury through inhibiting the activation of the NF-κB signaling pathway	0
Symposium 8	0
Topical administration of testosterone ameliorates atopic dermatitis of KFRS4 rats	0
Plenary Lecture 2	0
Loss of N-acetylglucosaminyl transferase V is involved in the impaired osteogenic differentiation of bone marrow mesenchymal stem cells	0
Establishment of a human microbiome- and immune system-reconstituted dual-humanized mouse model	0
Transcriptomics and metabolomics analysis of the pathogenesis of a novel hyperlipidemia-susceptible rat strain	0
Differences in susceptibility to ADR nephropathy among C57BL/6 substrains	0
Luminescent mouse model of endometriosis: three-dimensional morphology of lesions and cytokine profiles	0
Humanized CD36 (hCD36) mouse model supports the preclinical evaluation of therapeutic candidates targeting CD36	0
Functional role of IL-19 in a mouse model of L-arginine-induced pancreatitis and related lung injury	0
Differential regulation of K<sup>+</sup>-Cl<sup>−</sup> cotransporter 2 (KCC2) and Na<sup>+</sup>-K<sup>+</sup>-Cl<sup>−</sup> cotransporter	0
Intestinal epithelial cell-specific restoration of <i>Nrf2</i> gene in whole-body-knockout mice ameliorates acute colitis	0
Rat polyomavirus 2 infection: secondary publication	0
Generation of <i>c-Fos</i> knockout rats, and observation of their phenotype	0
Acyl-CoA thioesterase 1 (ACOT1) overexpression alleviates heart failure by inhibiting oxidative stress and cardiomyocyte apoptosis through the Kelch-like ECH-associated protein1-NF-E2-related factor2	0
Symposium 7	0
Activation of autophagy through Sirt1/AMPK/mTOR mediates the protective effects of fraxin against insulin resistance and steatosis in rats	0
Plenary Lecture 2	0
Sexual activity is predicted by digit ratio in rats	0
Beta-sitosterol mitigates cognitive deficit and hippocampal neurodegeneration in mice with trimethyltin-induced toxicity	0
Construction of a canine model with acute type B aortic dissection using a self-made pressure-driven flow device	0
Artesunate ameliorates experimental colitis by suppressing intestinal inflammation and modulating the gut microbiota	0
Protective effect of 8-Gingerol, a potent constituent of ginger, on acute lung injury following hemorrhagic shock in rats	0
Symposium 5	0
Effects of plant flavonoids and selenium on pancreatic hormones and glucose homeostasis in autoimmune thyroiditis	0
Evaluation of a mixture of medetomidine, alfaxalone and butorphanol as an alternative drug for euthanasia in mice	0
Changes in microbial prevalence in mice within Japanese academic animal facilities between 2011 and 2024	0
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model	0
Soyasaponin I alleviates inflammation and oxidative stress in chronic obstructive pulmonary disease through inhibiting the mitogen-activated protein kinase (MAPK) signaling pathway	0
Symposium 7	0
The analgesic effects of dezocine in rats with chronic constriction injuries	0
Age-related changes in lung function in National Center for Geriatrics and Gerontology Aging Farm C57BL/6N mice	0
A partial deletion of the <i>Tardbp</i> 3’UTR affects TDP-43 regulation and leads to motor dysfunction in mice	0
Young Investigator Award	0
Neuroprotective effect of safflower yellow in mice with cerebral ischemia reperfusion injury	0
Middle aged CAMKII-Cre:<i>Cbs<sup>fl/fl</sup></i> mice: a new model for studying perioperative neurocognitive disorders	0
Symposium 5	0
The protective effects of retinoic acid-induced protein 14 on ischemia/reperfusion-induced myocardial apoptosis involves over-autophagy repression	0
Involvement of gut microbiota recovery and autophagy induction in Youhua Kuijie formula’s protection against experimental ulcerative colitis	0
Moderate hyperglycemia suppresses melanoma metastasis to liver	0
Transmembrane protein modulates seizure in epilepsy: evidence from temporal lobe epilepsy patients and mouse models	0
A novel early onset spinocerebellar ataxia 13 BAC mouse model with cerebellar atrophy, tremor, and ataxic gait	0
Symposium 5	0
Effect of post-weaning diet on hibernation occurrence in Syrian hamsters	0
Neuroprotective effects of betanin in mice with cerebral ischemia-reperfusion injury	0