OOIR: Observatory of International Research

Papers

(The TQCC of Breast Cancer is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Deciphering the nexus between the tumor immune microenvironment and DNA methylation in subgrouping estrogen receptor-positive breast cancer	123
Integrated analysis of cell cycle-related genes in HR+/HER2− breast cancer	49
The hub ten gene-based risk score system using RNA m6A methylation regulator features and tumor immune microenvironment in breast cancer	41
Quality of life improvement in breast cancer survivors affected by upper limb lymphedema through a novel multiperspective physical activity methodology: a monocentric pilot study	39
Incidence of and risk factors for non-hematologic toxicity with combined radiotherapy and CDK4/6 inhibitors in metastatic breast cancer using dose-volume parameters analysis: a multicenter cohort stud	38
Assessment of nuclear grade-based recurrence risk classification in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative, node-positive high-risk early breast can	32
Identification of key tumor stroma-associated transcriptional signatures correlated with survival prognosis and tumor progression in breast cancer	29
Validation of a nuclear grading system for resected stage I–IIIA, high-risk, node-negative invasive breast carcinoma in the N·SAS-BC 01 trial	27
Reply to “Is venous thromboembolism a time-dependent event in breast cancer patients taking tamoxifen?”	25
Number of lines of previous chemotherapy regimen might affect the oucome of sacituzumab govitecan in metastatic triple-negative breast cancer patients	23
Average lifespan shortened due to breast cancer in Australia, 1990–2015	22
New variant of breast-invasive lobular carcinoma with solid and encapsulated papillary carcinoma growth pattern	22
Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients	22
Effect of Apatinib plus melatonin on vasculogenic mimicry formation by cancer stem cells from breast cancer cell line	22
Identifying ductal carcinoma in situ cases not requiring surgery to exclude postoperative upgrade to invasive ductal carcinoma	21
Comparing survival outcomes between neoadjuvant and adjuvant chemotherapy within breast cancer subtypes and stages among older women: a SEER-Medicare analysis	20
Oncoplastic versus conventional breast-conserving surgery in breast cancer: a pooled analysis of 6941 female patients	19
Correction: Clinicopathological significance of androgen receptor expression and tumor infiltrating lymphocytes in triple-negative breast cancer: a retrospective cohort study	19
The Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer, 2022 Edition: changes from the 2018 edition and general statements on breast cancer treatment	19
Community-based outpatient rehabilitation for the treatment of breast cancer-related upper extremity disability: an evaluation of practice-based evidence	18
Factors associated with post acute care utilization after mastectomy for breast cancer patients	17
The role of C1orf50 in breast cancer progression and prognosis	17
Factors associated with non-participation in breast cancer screening: analysis of the 2016 and 2019 comprehensive survey of living conditions in Japan	15
SET-binding protein 1 (SETBP1) suppresses cell proliferation in estrogen receptor-positive breast cancer	14
Survival advantage of locoregional and systemic therapy in oligometastatic breast cancer: an international retrospective cohort study (OLIGO-BC1)	13

Relevance of the MHC region for breast cancer susceptibility in Asians	13
Trastuzumab deruxtecan versus treatment of physician’s choice in previously treated Asian patients with HER2-low unresectable/metastatic breast cancer: subgroup analysis of the DESTINY-Breast04 study	13
Factors affecting prognosis in patients treated with bevacizumab plus paclitaxel as first-line chemotherapy for HER2-negative metastatic breast cancer: an international pooled analysis of individual p	13
ER–/PR+ breast cancer is controlled more effectively with an inflammatory inhibitor than hormonal inhibitor	12
The involvement of axillary reverse mapping nodes in patients with clinically node-negative breast cancer	12
Investigation of recurrence prediction ability of EndoPredict® using microarray data from fresh frozen tissues in ER-positive, HER2-negative breast cancer and indication expansion of EndoPredict® from	12
Prognostic impact of tumor‑associated stroma in triple-negative breast cancer	11
HER2-targeted antibody–drug conjugates for breast cancer: ancestry and dose adjustment for thrombocytopenia	11
Utility of a breast biopsy clip and a point marker system in tailored axillary surgery for patients with breast cancer after neoadjuvant chemotherapy	11
Glutaminase (GLS1) gene expression in primary breast cancer	11
Dynamic tumor microenvironment, molecular heterogeneity, and distinct immunologic portrait of triple-negative breast cancer: an impact on classification and treatment approaches	11
Hepatitis C virus may accelerate breast cancer progression by increasing mutant p53 and c-Myc oncoproteins circulating levels	11
Quercetin: a silent retarder of fatty acid oxidation in breast cancer metastasis through steering of mitochondrial CPT1	10
Resilience’s impact on quality of life and post-traumatic growth in breast cancer patients during treatment	10
Breast cancer screening guidelines: discrepancies raise concerns about validity	10
Impact of exercise interventions on physical fitness in breast cancer patients and survivors: a systematic review	10
21-gene recurrence score predictive of the benefit of postoperative radiotherapy after breast-conserving surgery for elderly patients with T1N0 and luminal breast cancer	10
What do we know about treating breast-cancer-related lymphedema? Review of the current knowledge about therapeutic options	10
Efficacy and safety of surgical energy devices for axillary node dissection: a systematic review and network meta-analysis	10
c-Myc knockdown restores tamoxifen sensitivity in triple-negative breast cancer by reactivating the expression of ERα: the central role of miR-152 and miR-148a	10
Association between chronic pain and quality of life in long-term breast cancer survivors: a prospective analysis	10
Comparison of locoregional recurrence risk among nipple-sparing mastectomy, skin-sparing mastectomy, and simple mastectomy in patients with ductal carcinoma in situ: a single-center study	9
FE65 in breast cancer and its clinicopathological significance	9
Immunohistological analysis of B7-H4, IDO1, and PD-L1 expression and tumor immune microenvironment based on triple-negative breast cancer subtypes	9
Resveratrol exhibits diverse anti-cancer activities through epigenetic regulation of E-cadherin and p21 in triple-negative breast cancer cells	9
6q deletion is frequent but unrelated to patient prognosis in breast cancer	9
Pre-pectoral breast reconstruction: early and long-term safety evaluation of 146 unselected cases of the early pre-pectoral era of a single-institution, including cases with previous breast irradiatio	9
Acute toxicity of hypofractionated radiotherapy for Japanese breast cancer patients after surgery: a single center prospective observational study (HyPORT-BC)	9
Impact of artificial intelligence in breast cancer screening with mammography	9
Concordance of HER2 status between core needle biopsy and surgical resection specimens of breast cancer: an analysis focusing on the HER2-low status	9
Clinicopathological differences and survival benefit in ER+/PR+/HER2+ vs ER+/PR−/HER2+ breast cancer subtypes	9
Targeted therapies in HER2-positive breast cancer with receptor-redirected Arazyme-linker-Herceptin as a novel fusion protein	9
Radiation-induced angiosarcoma of the breast: individual participant meta-analysis of Japanese population	8
Capecitabine with aromatase inhibitors in the front-line therapy for metastatic breast cancer	8
Neoadjuvant nivolumab plus bevacizumab therapy improves the prognosis of triple-negative breast cancer in humanized mouse models	8
Breast cancer statistics for Japan in 2022: annual report of the national clinical database-breast cancer registry—clinical implications including chemosensitivity of breast cancer with low estrogen r	8
The effect of combined risk factors on breast cancer-related lymphedema: a study using decision trees	8
Dynamic changes in quality of life, psychological status, and body image in women who underwent a mastectomy as compared with breast reconstruction: an 8-year follow up	8
Color differences of skin paddles using the free flap for autologous breast reconstruction in Asian patients	8
Association between preoperative grip strength and postoperative upper extremity impairments in patients with breast cancer: a retrospective cohort study	8
Characteristics of female breast cancer in japan: annual report of the National Clinical Database in 2018	8
Clinical outcome of patients with isolated central nervous system progression on first-line pertuzumab and trastuzumab treatment for HER2-positive metastatic breast cancer in a real-life cohort	7
Machine learning applied in patient-reported outcome research—exploring symptoms in adjuvant treatment of breast cancer	7
Case series of Li-Fraumeni syndrome: carcinogenic mechanisms in breast cancer with TP53 pathogenic variant carriers	7
Does axillary lymph node recurrence breast cancer subtype information matter for prognosis estimation?	7
Medical care costs according to the stage and subtype of breast cancer in a municipal setting: a case study of Hachioji City, Japan	7
Prognostic effect of subsequent childbirth after the diagnosis of breast cancer using propensity score matching analysis	7
Single HER2-positive tumor cells are detected in initially HER2-negative breast carcinomas using the DEPArray™–HER2-FISH workflow	7
BAP1-defficient breast cancer in a patient with BAP1 cancer syndrome	6
Global untargeted and individual targeted plasma metabolomics of breast cancer recurrence modified by hormone receptors	6

Impact of oral hygiene on febrile neutropenia during breast cancer chemotherapy	6
Performance analysis of screening mammography in Asian women under 40 years	6
CD1a- and CD83-positive dendritic cells as prognostic markers of metastasis development in early breast cancer patients	6
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants	6
Acute adverse events of ultra-hypofractionated whole-breast irradiation after breast-conserving surgery for early breast cancer in Japan: an interim analysis of the multi-institutional phase II UPBEAT	6
Efficacy and safety of adjuvant therapies in older patients with breast cancer: a systematic review and meta-analysis of real-world data	6
Identification and validation of screening models for breast cancer with 3 serum miRNAs in an 11,349 samples mixed cohort	6
Sensitivity and specificity of screening mammography without clinical breast examination among Japanese women aged 40–49 years: analysis of data from the J-START results	6
A prospective cohort study of abemaciclib-induced interstitial lung disease in metastatic breast cancer after chemotherapy	6
The effectiveness of moisturizer on acute radiation-induced dermatitis in breast cancer patients: a systematic review and meta-analysis	6
Overexpression of MCAM induced by SMYD2-H3K36me2 in breast cancer stem cell properties	6
Delayed breast reconstruction with autologous free flap after radiation therapy: vascular complications and aesthetic outcomes	6
Development of a nomogram to predict recurrence scores obtained using Oncotype DX in Japanese patients with breast cancer	6
The complex role of regulatory cells in breast cancer: implication for immunopathogenesis and immunotherapy	6
Population-level impact of adjuvant trastuzumab emtansine on the incidence of metastatic breast cancer: an epidemiological prediction model of women with HER2-positive early breast cancer and residual	5
Comparing survival outcomes between neoadjuvant and adjuvant chemotherapy within T2N1M0 stage hormone receptor-positive, HER2-negative breast cancer: a retrospective cohort study based on SEER databas	5
Assessment of the cardiorespiratory fitness and the quality of life of patients with breast cancer undergoing chemotherapy: a prospective study	5
Liquid biopsy using non-coding RNAs and extracellular vesicles for breast cancer management	5
Physicians’ perception about the impact of breast reconstruction on patient prognosis: a survey in Japan	5
Specific types of anxiety regarding radiation therapy in patients with breast cancer: a longitudinal study	5
Racial and socioeconomic inequities in breast cancer screening before and during the COVID-19 pandemic: analysis of two cohorts of women 50 years +	5
Patient preferences for features of HER2-targeted treatment of advanced or metastatic breast cancer: a discrete-choice experiment study	5
FOXA1 of regulatory variant associated with risk of breast cancer through allele-specific enhancer in the Chinese population	5
SLC38A5 promotes glutamine metabolism and inhibits cisplatin chemosensitivity in breast cancer	5
An integrated analysis of microRNAs regulating DNA damage response in triple-negative breast cancer	5
Management of nausea and vomiting induced by antibody–drug conjugates	5
Patterns of treatment and their outcomes in primary breast lymphoma; a comprehensive population-based analysis	5
Repeated sentinel lymph node biopsy for local recurrence after breast-conserving surgery	5
Options of locoregional therapy for primary foci of breast cancer influence the rate of nonregional lymph node metastasis in N2–N3 status patients: a SEER database analysis	5
Endoscopic mastectomy followed by immediate breast reconstruction with fat grafting for breast cancer	5
Psychometric evaluation of the Chinese version of the breast cancer perception scale for community women: a translation and validation study	5
Identification of prognostic genes signature and construction of ceRNA network in pirarubicin treatment of triple-negative breast cancer	5
Correction: The Japanese breast cancer society clinical practice guidelines for breast cancer screening and diagnosis, 2022 edition	5
High-risk pathogenic germline variants in blood relatives of BRCA1/2 negative probands	5
Non-irradiated area of intraoperative radiotherapy with electron technique: outcomes and pattern of failure in early-stage breast cancer from a single-center, registry study	5
Impact of serum vitamin D on the response and prognosis in breast cancer patients treated with neoadjuvant chemotherapy	5
Evaluation of quality of life in breast cancer patients who underwent breast-conserving surgery or mastectomy using real-world data	5
A novel system to provide information via online YouTube videos and an evaluation of current online information about hereditary breast cancer	4
LncRNA SNHG5 promotes the glycolysis and proliferation of breast cancer cell through regulating BACH1 via targeting miR-299	4
Programmed death ligand 1-positive immune cells in primary tumor or metastatic axillary lymph nodes can predict prognosis of triple-negative breast cancer even when present at < 1% in the tumor reg	4
Prognosis of isolated locoregional recurrence after early breast cancer with immediate breast reconstruction surgery: a retrospective multi‑institutional study	4
Postoperative cholesterol changes as early predictors of breast cancer-related lymphedema: a retrospective cohort study	4
Development and validation of a symptom illustration scale from the patient-reported outcome common terminology criteria for adverse events for patients with breast cancer	4
Prospective study of once-daily accelerated partial breast irradiation using 3-dimensional conformal external beam radiotherapy for Japanese women: 12-year outcomes, toxicity, and cosmesis	4
Racial differences in predictive value of the 21-gene recurrence score assay: a population-based study using the SEER database	4
Japanese subgroup analysis of the phase 3 MONARCH 3 study of abemaciclib as initial therapy for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced brea	4
Cost-effectiveness of clinical breast examination screening programme among HER2-positive breast cancer patients: a modelling study	4
Evaluation of the ability of the Clinical Treatment Score at 5 years (CTS5) compared to other risk stratification methods to predict the response to an extended endocrine therapy in breast cancer pati	4
Negative impact of the COVID-19 state of emergency on breast cancer screening participation in Japan	4
Does breast-conserving surgery with radiotherapy in BRCA-mutation carriers significantly increase ipsilateral breast tumor recurrence? A systematic review and meta-analysis	4
Breast cancer drugs: FDA approval, development time, efficacy, clinical benefits, innovation, trials, endpoints, quality of life, value, and price	4
IRSN-23 gene diagnosis enhances breast cancer subtype classification and predicts response to neoadjuvant chemotherapy: new validation analyses	4
Breast cancer patient-reported outcome of factors influencing cosmetic satisfaction after breast-conserving therapy	4
Clinical benefits of tomosynthesis-guided vacuum assisted breast biopsy: a comparison with stereotactic vacuum assisted biopsy	4
A novel approach correlating pathologic complete response with digital pathology and radiomics in triple-negative breast cancer	4
Contrast-enhanced mammography in the management of breast architectural distortions and avoidance of unnecessary biopsies	4
Impact of community-based exercise on fatigue in early breast cancer survivors: identifying potential determinants of change	4
Prognosis difference between HER2-low and HER2-zero breast cancer patients: a systematic review and meta-analysis	4
Predictive value of immune genomic signatures from breast cancer cohorts containing data for both response to neoadjuvant chemotherapy and prognosis after surgery	4
Development and validation of a neoadjuvant chemotherapy pathological complete remission model based on Reg IV expression in breast cancer tissues: a clinical retrospective study	4
Is venous thromboembolism a time-dependent event in breast cancer patients taking tamoxifen?	4
BAHD1 serves as a critical regulator of breast cancer cell proliferation and invasion	4
Correlation between postoperative treatment selection and prognosis determined using the Oncotype DX® test data: a retrospective multicenter study in Japan	4
Acknowledgments to reviewers 2023	4
Overall survival in Japanese patients with ER+/HER2− advanced breast cancer treated with first-line palbociclib plus letrozole	4
Breast cancer screening rates and influencing factors among LGBTQ groups in Japan	4
Effect of patient decision aids on decisional conflict and regret associated with breast cancer surgery: a randomized controlled trial	4
Interstitial lung disorders following postoperative radiotherapy with concurrent or sequential hormonal therapy for breast cancer: a nationwide database study in Japan	4
Increasing survivors of anthracycline-related cardiomyopathy with breast cancer in trastuzumab era: thirty-one-year trends in a Japanese Community	4
Correction to: Prevalence of mutations in BRCA and homologous recombination repair genes and real-world standard of care of Asian patients with HER2-negative metastatic breast cancer starting first-li	4
Comparative study of the usefulness of adjunctive tomosynthesis in breast cancer screening by mammography and ultrasound in Japan	4
CHEOPS trial: a GINECO group randomized phase II assessing addition of a non-steroidal aromatase inhibitor to oral vinorelbine in pre-treated metastatic breast cancer patients	4
Simultaneous integrated boost intensity-modulated radiotherapy post breast-conserving surgery: clinical efficacy, adverse effects, and cosmetic outcomes in breast cancer patients	4
Predictive and prognostic significance of BRCAness in HER2-negative breast cancer	4
A prospective comparison study utilizing patient-reported outcomes of taxane-related peripheral neuropathy between nab-paclitaxel and standard paclitaxel in patients with breast cancer	4
Correction to: Effect of Wnt5a on drug resistance in estrogen receptor‑positive breast cancer	4
Editorial: HBOC and high-risk screening: up-to-date	4